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The skin reactivity of guinea-pigs sensitized with heat-killed mycobacteria of six different species was studied. Animals sensitized with Mycobacterium ulcerans showed strong reactivity to suspensions of the homologous organism and some cross-reactivity with other mycobacteria, especially mammalian tubercle bacilli. They also reacted strongly to the inoculation of mammalian but not avian P.P.D. tuberculin. Animals sensitized with mammalian tubercle baccili (BCG) reacted to Mycobacterium ulcerans, but to a lesser degree than the reverse relationships. [ABSTRACT FROM AUTHOR]

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