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The article focuses on the initiation and development of schizophrenia. It has been stated in a recent theory that the disorder is confined to people with a genetic predisposition. It also stemmed from a specific breakdown in the central part of the system responsible for growth control. Initiation of schizophrenia is a form of spontaneous somatic gene mutation in growth-control stem cells. During development, lymphocytes increase rapidly and attack target cells that transport recognition molecules complementary to those borne by the mutant lymphocytes. According to research, the most probable initiation of the disorder is 20 years. A study of pairs of monozygotic twins living together and for pairs living apart at the time of onset in the first twin is also presented.