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Your search keyword '"Xu, Ling-Ling"' showing total 289 results
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289 results on '"Xu, Ling-Ling"'

7. Characterization and pathogenicity of Alternaria species associated with leaf spot on Plantago lanceolata in Sichuan Province, China.

Author

Xu, Zhi‐Ting, Long, Jia‐Hui, Liu, Jia‐Qi, Zhang, Rui‐Zhen, Xu, Ling‐Ling, Wang, Jian‐Jun, Wei, Xue‐Kai, White, James F., Kamran, Malik, Cui, Hua‐Wei, Xue, Long‐Hai, Li, Chun‐Jie, and Yue, Shang‐Kun

Subjects
ALTERNARIA, FEED quality, DATABASES, PLANTAGO, PHYLOGENY, LEAF spots
Abstract

Plantago lanceolata has been increasingly cultivated in recent years as a forage crop due to its high feeding quality, good adaptability and medicinal benefits. Between 2015 and 2023, Alternaria leaf spot (ALS), appearing as reddish‐brown necrotic spots with a greyish white to pale brown centre, was commonly observed in two forage germplasm nurseries of P. lanceolata of Sichuan Province, China. Initially, 139 Alternaria strains were isolated from leaf lesions, and then identified using the identity of rDNA internal transcribed spacer (ITS) sequences in the NCBI database and the similarity of morphological characteristics. By pure culture technique, six representative isolates were finally obtained for the present study. Based on both multilocus phylogeny (SSU, LSU, ITS, gapdh, rpb2, tef1, endoPG, OPA10‐2, alt a 1, KOG1058 and KOG1077) and morphology, four Alternaria species were identified: three new records of A. alternata, A. arborescens species complex and A. gossypina on this host in China, belonging to section Alternaria, and a new species of section Porri, namely, A. lanceolatae sp. nov. Pathogenicity tests by inoculation on both detached leaves and whole plants revealed that A. lanceolatae was the most important causal agent of ALS, while the other three species were nonpathogenic to P. lanceolata. This study characterized a novel pathogenic Alternaria species of section Porri from P. lanceolata in China and could contribute as useful research for possible ALS management. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Crohn’s disease as the intestinal manifestation of pan-lymphatic dysfunction: An exploratory proposal based on basic and clinical data

Author

Zhou, Yu-Wei, primary, Ren, Yue, additional, Lu, Miao-Miao, additional, Xu, Ling-Ling, additional, Cheng, Wei-Xin, additional, Zhang, Meng-Meng, additional, Ding, Lin-Ping, additional, Chen, Dong, additional, Gao, Jian-Guo, additional, Du, Juan, additional, Jin, Ci-Liang, additional, Chen, Chun-Xiao, additional, Li, Yun-Fei, additional, Cheng, Tao, additional, Jiang, Peng-Lei, additional, Yang, Yi-Da, additional, Qian, Peng-Xu, additional, Xu, Peng-Fei, additional, and Jin, Xi, additional

Published
2024
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13. Common key ingredient concluded in Baitouweng decoction, Gegen Qinlian decoction and Shaoyao decoction prevents radiation enteritis by regulating gut microbial network

Author

Liu, Tian-hao, primary, Sheng, Ying-yue, additional, Zhang, Chen-yang, additional, Zhang, Hang, additional, Li, Xue, additional, Yu, Li-hua, additional, Xu, Ling-ling, additional, Zhao, Lin, additional, Wei, Hong, additional, Zhou, Ya-hong, additional, and Xue, Yu-zheng, additional

Published
2024
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16. TRPV1 and GABAB1 in the Cerebrospinal Fluid-Contacting Nucleus are Jointly Involved in Chronic Inflammatory Pain in Rats

Author

Xu,Ling-Ling, Yan,Yao, Yuan,Yu-Min, Li,Ying, Jiang,Jun, and Zhang,Li-Cai

Subjects
Anesthesiology and Pain Medicine, Journal of Pain Research
Abstract

Ling-Ling Xu,1– 4,* Yao Yan,1– 3,* Yu-Min Yuan,1– 3 Ying Li,1– 3 Jun Jiang,1– 3 Li-Cai Zhang1– 3 1Jiangsu Province Key Laboratory of Anesthesiology, Xuzhou Medical University, Xuzhou, People’s Republic of China; 2Jiangsu Province Key Laboratory of Anesthesia and Analgesia Application Technology, Xuzhou Medical University, Xuzhou, People’s Republic of China; 3NMPA Key Laboratory for Research and Evaluation of Narcotic and Psychotropic Drugs, Xuzhou, People’s Republic of China; 4Department of Anesthesiology, Nanjing Gaochun People’s Hospital, Nanjing, People’s Republic of China*These authors contributed equally to this workCorrespondence: Li-Cai Zhang, Email licaizhang001@163.comObjective: To assess the receptors of TRPV1 and GABAB1 receptors that were colocalized in cerebrospinal fluid contacting nucleus (CSF-contact nucleus) of chronic inflammatory pain (CIP) rats bringing inspiration for reducing chronic pain.Methods: A rat model of CIP was constructed by plantar injection of complete Freund’s adjuvant (CFA), and the paw withdrawal mechanical threshold (PWMT) and paw withdrawal thermal latency (PWTL) were measured 1, 3, 5, 7, 10, and 14 days after plantar injection. In the first part of the experiment, rats with CIP were divided into the immunofluorescence group and the coimmunoprecipitation (Co-IP) group (n = 6). Rats in the immunofluorescence group were injected with the retrograde tracer CB conjugated with Alexa Fluor 594 into the lateral ventricle two days before the injection of CFA into the plantar surface of the left paw. Three days later, rats that exhibited hyperalgesia were perfused, and their brains were extracted and used for double immunofluorescence staining of the CSF-contacting nucleus. Rats in the Co-IP group were anesthetized and dissected 3 days after CFA injection, and fresh brain segments containing the CSF-contacting nucleus were collected for Co-IP to assess the colocalization of TRPV1 and GABAB1 in the CSF-contacting nucleus (n = 6). In the second part of the experiment, SD rats were divided into the normal saline group (control group) and the CFA group. Fresh CSF-contacting nucleus-containing tissues were collected for Western blot analysis 3 days after plantar injection to observe the changes in TRPV1 and GABAB1 expression in the CSF-contacting nucleus.Results: TRPV1 and GABAB1 were co-expressed in the CSF-contacting nucleus in rats with CIP, and their expression was upregulated.Conclusion: TRPV1 and GABAB1 in the CSF-contacting nucleus are jointly involved in CIP in rats, and there is a direct or indirect link between TRPV1 and GABAB1.Keywords: cerebrospinal fluid-contacting nucleus, TRPV1 receptor, GABAB1 receptor, chronic inflammatory pain

Published
2022

19. Research Trends of the Research and Development of Acupuncture and Moxibustion Therapy on Lumbar Disc Herniation: A Bibliometric Analysis

Author

Li,Yu-Xin, Xiong,Jun, Zhang,Zheng, Liao,Kai, Zhou,Xiao-Hong, Li,Jun, Xiang,Jie, Xu,Ling-Ling, Li,Yu-Xin, Xiong,Jun, Zhang,Zheng, Liao,Kai, Zhou,Xiao-Hong, Li,Jun, Xiang,Jie, and Xu,Ling-Ling

Abstract

Yu-Xin Li,1 Jun Xiong,2 Zheng Zhang,2 Kai Liao,2 Xiao-Hong Zhou,2 Jun Li,2 Jie Xiang,2 Ling-Ling Xu2 1Graduate School, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, People’s Republic of China; 2College of Acupuncture and Massage, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, People’s Republic of ChinaCorrespondence: Jun Xiong, College of Acupuncture and Massage, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, 330004, People’s Republic of China, Email xiongjun196071@163.comBackground: Acupuncture and moxibustion has been applied worldwide in the treatment of various pain diseases including lumbar disc herniation (LDH) and other pain, However, there has been no bibliometric analysis on this aspect in the past five years. Therefore, this study was carried out for finding research trends and fronts in this field using Citespace and VOSviewer.Methods: Publications about acupuncture therapy for LDH were extracted from the Web of Science database and PubMed with an unlimited time frame. A bibliometric analysis and visualization of results was conducted using CiteSpace 6.1.R3 and VOSviewer 1.6.18 on the information of the annual publication, countries, journals, institutions, authors, references, and keywords.Results: A total of 127 publications were included, and the number of publications had increased noticeably over the past 30 years and reached a peak in the past 3 years. The most productive country with the most publications was China, whose Medical University was the institution with the highest volume of publications. The most productive author was Chen Rixin, while the most-cited author was Kreiner DS. Chinese Acupuncture and Moxibustion was the journal with the most publications, and Spine Journal was the most frequently cited journal. In cited references, an article published in The New England Journal of Medicine by Deyo RA had the most citations and the highest centrality. Of the keywords, the five most frequently used

Published
2023

23. High-fat diet aggravates colitis via mesenteric adipose tissue derived exosome metastasis-associated lung adenocarcinoma transcript 1

Author

Chen, Dong, primary, Lu, Miao-Miao, additional, Wang, Jin-Hai, additional, Ren, Yue, additional, Xu, Ling-Ling, additional, Cheng, Wei-Xin, additional, Wang, Sai-Sai, additional, Li, Xiao-Lin, additional, Cheng, Xiao-Fei, additional, Gao, Jian-Guo, additional, Kalyani, Farhin Shaheed, additional, and Jin, Xi, additional

Published
2022
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24. Gut microbiota mediates methamphetamine-induced hepatic inflammation via the impairment of bile acid homeostasis

Author

Zhang, Kai-Kai, primary, Liu, Jia-Li, additional, Chen, Li-Jian, additional, Li, Jia-Hao, additional, Yang, Jian-Zheng, additional, Xu, Ling-Ling, additional, Chen, Yu-Kui, additional, Zhang, Qin-Yao, additional, Li, Xiu-Wen, additional, Liu, Yi, additional, Zhao, Dong, additional, Xie, Xiao-Li, additional, and Wang, Qi, additional

Published
2022
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36. Antibiotics Attenuate Methamphetamine-Induced Hepatotoxicity by Regulating Oxidative Stress and TLR4/MyD88/Traf6 Axis

Author

Chen, Li-Jian, primary, He, Jie-Tao, additional, Pan, Ming, additional, Liu, Jia-Li, additional, Zhang, Kai-Kai, additional, Li, Jia-Hao, additional, Wang, Li-Bin, additional, Xu, Ling-Ling, additional, Chen, Yu-Kui, additional, Zhang, Qin-Yao, additional, Li, Dong-Ri, additional, Xu, Jing-Tao, additional, and Xie, Xiao-Li, additional

Published
2021
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43. Luteolin Alleviates Methamphetamine-Induced Hepatotoxicity by Suppressing the p53 Pathway-Mediated Apoptosis, Autophagy, and Inflammation in Rats

Author

Zhang, Kai-Kai, primary, Wang, Hui, additional, Qu, Dong, additional, Chen, Li-Jian, additional, Wang, Li-Bin, additional, Li, Jia-Hao, additional, Liu, Jia-Li, additional, Xu, Ling-Ling, additional, Yoshida, Jamie Still, additional, Xu, Jing-Tao, additional, Xie, Xiao-Li, additional, and Li, Dong-Ri, additional

Published
2021
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45. Additional file 1 of SGLT2 inhibitors and atrial fibrillation in type 2 diabetes: a systematic review with meta-analysis of 16 randomized controlled trials

Author

Li, Wen-Jie, Xing-Qing Chen, Xu, Ling-Ling, Li, Yuan-Qing, and Luo, Bi-Hui

Abstract

Additional file 1: Figure S1: Forest plot and subgroup meta-analysis of atrial fibrillation/atrial flutter events. Weights are from the fixed-effect analysis. The solid line across the square represents the 95% confidence interval (CI). Figure S2. Forest plot and meta-analysis of heart failure. Weights are from the fixed-effect analysis. The solid line across the square represents the 95% confidence interval (CI). Figure S3. Forest plot and meta-analysis of cerebrovascular events. Weights are from the fixed-effect analysis. The solid line across the square represents the 95% confidence interval (CI). Figure S4. Forest plot and meta-analysis of myocardial infarction. Weights are from the fixed-effect analysis. The solid line across the square represents the 95% confidence interval (CI). Figure S5. Forest plot and meta-analysis of urinary tract infection rate. Weights are from the fixed-effect analysis. The solid line across the square represents the 95% confidence interval (CI). Figure S6: Forest plot and meta-analysis of adjusted mean HbA1c change from baseline for low dosage. Weights are from the random-effect analysis. The solid line across the square represents the 95% confidence interval (CI). Figure S7. Forest plot and meta-analysis of adjusted mean HbA1c change from baseline for high dosage. Weights are from the random-effect analysis. The solid line across the square represents the 95% confidence interval (CI). Figure S8. Forest plot and meta-analysis of adjusted mean body weight loss change from baseline for low dosage. Weights are from the random-effect analysis. The solid line across the square represents the 95% confidence interval (CI). Figure S9. Forest plot and meta-analysis of adjusted mean body weight loss change from baseline for low dosage. Weights are from the random-effect analysis. The solid line across the square represents the 95% confidence interval (CI). Figure S10. Forest plot and meta-analysis of adjusted mean SBP change from baseline for high dosage. Weights are from the fixed-effect analysis. The solid line across the square represents the 95% confidence interval (CI). SBP: systolic blood pressure. Figure S11. Forest plot and meta-analysis of adjusted SBP change from baseline for high dosage. Weights are from the fixed-effect analysis. The solid line across the square represents the 95% confidence interval (CI). SBP: systolic blood pressure. Figure S12. Forest plot and meta-analysis of adjusted DBP change from baseline for low dosage. Weights are from the fixed-effect analysis. The solid line across the square represents the 95% confidence interval (CI). DBP: diastolic blood pressure. Figure S13. Forest plot and meta-analysis of adjusted DBP change from baseline for high dosage. Weights are from the fixed-effect analysis. The solid line across the square represents the 95% confidence interval (CI). DBP: diastolic blood pressure. Figure S14. Random effect meta-regression for adjusted mean HbA1c (%) change from baseline with the following covariates: (A) female proportion (%) (B) duration of follow-ups (year), and (C) sample sizes.

Published
2020
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46. Advances in research on microbial leaching of uranium

Author

Wen Xu-Xiang, Liu Shun-Liang, Sun Zhan-Xue, Xu Ling-Ling, Zhou Yi-Peng, Wen Xu-Xiang, Liu Shun-Liang, Sun Zhan-Xue, Xu Ling-Ling, and Zhou Yi-Peng

Abstract

With the increasing demand of natural uranium, the exploitation of low-grade or complex uranium ores has been attracting more and more attention. Biological leaching is one of the important techniques for exploitation of such uranium resources. At present, heap leaching and in-situ leaching are the main processes for uranium recovery. A number of laboratory experiments and field trials show that the microbial leaching is a feasible technique for industrial production of uranium from low-grade or refractory ores. The tolerance of microorganisms which have been mutated and acclimatised can be improved obviously and it can be adapted to high fluorine uranium ores, low temperature and high acidity environments. For example, the acclimatised bacteria can grow well in mining tailings with fluorine content of 2-3.98 g/l, under the conditions of a low temperature of 8 degrees C and in a solution with pH 1.2-2.0 or even in a higher acidity solution (pH 0.6). Acclimatisation and induction are common technical ways to improve the adaptability of bacteria species to a leaching environment and indigenous bacteria often have better adaptability to native mining areas. The results also show that there is a synergistic effect between mixed strains and the leaching effect is better than that of a single strain. The indirect action of microbial leaching on uranium ore is clear, but the view on direct action of microorganisms on uranium ore is still controversial. The mechanism of uranium leaching by microorganism, the study of tolerance, the breeding of bacteria and research on the practical application of microbial leaching uranium technology were reviewed, especially in the past 20 years. The development of bioleaching of uranium, especially in-situ leaching, was investigated., With the increasing demand of natural uranium, the exploitation of low-grade or complex uranium ores has been attracting more and more attention. Biological leaching is one of the important techniques for exploitation of such uranium resources. At present, heap leaching and in-situ leaching are the main processes for uranium recovery. A number of laboratory experiments and field trials show that the microbial leaching is a feasible technique for industrial production of uranium from low-grade or refractory ores. The tolerance of microorganisms which have been mutated and acclimatised can be improved obviously and it can be adapted to high fluorine uranium ores, low temperature and high acidity environments. For example, the acclimatised bacteria can grow well in mining tailings with fluorine content of 2-3.98 g/l, under the conditions of a low temperature of 8 degrees C and in a solution with pH 1.2-2.0 or even in a higher acidity solution (pH 0.6). Acclimatisation and induction are common technical ways to improve the adaptability of bacteria species to a leaching environment and indigenous bacteria often have better adaptability to native mining areas. The results also show that there is a synergistic effect between mixed strains and the leaching effect is better than that of a single strain. The indirect action of microbial leaching on uranium ore is clear, but the view on direct action of microorganisms on uranium ore is still controversial. The mechanism of uranium leaching by microorganism, the study of tolerance, the breeding of bacteria and research on the practical application of microbial leaching uranium technology were reviewed, especially in the past 20 years. The development of bioleaching of uranium, especially in-situ leaching, was investigated.

Published
2020

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