361 results on '"Witztum, J L"'
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2. Role of Apolipoprotein E in the Lipolytic Conversion of β -Very Low Density Lipoproteins to Low Density Lipoproteins in Type III Hyperlipoproteinemia
3. Oxidation-specific epitopes are important targets of innate immunity
4. Complement C1q plays a bidirectional role in early atherosclerotic lesions in LDL receptor knock-out mice
5. Neo-self Antigens and the Expansion of B-1 Cells: Lessons from Atherosclerosis-prone Mice
6. Immune responses to oxidative neoepitopes on LDL and phospholipids modulate the development of atherosclerosis
7. Apolipoprotein C-III inhibition with volanesorsen in patients with hypertriglyceridemia (COMPASS): A randomized, double-blind, placebo-controlled trial
8. Treatment With Volanesorsen (VLN) Reduced Triglycerides and Pancreatitis in Patients With Familial Chylomicronemia Syndrome (FCS) and Severe Hypertriglyceridemia (sHTG) vs Placebo: Results of the Approach and Compass Studies
9. Stoffwechsel I
10. The secretion of lipoprotein lipase by mononuclear phagocytes
11. Volanesorsen and Triglyceride Levels in Familial Chylomicronemia Syndrome.
12. PREVALENCE OF LPA SINGLE NUCLEOTIDE POLYMORPHISMS AND ISOFORMS IN PATIENTS ENROLLED IN A PHASE 2 IONIS-APO(A)(RX) CLINICAL TRIAL
13. Autotaxin interacts with lipoprotein(a) and oxidized phospholipids in predicting the risk of calcific aortic valve stenosis in patients with coronary artery disease
14. Interaction of human endothelial cells with elevated glucose concentrations and native and glycosylated low density lipoproteins
15. Expression of the peroxisome proliferator-activated receptor gamma (PPARgamma) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein
16. High plasma leptin levels confer increased risk of atherosclerosis in women with systemic lupus erythematosus, and are associated with inflammatory oxidised lipids
17. Oxidative damage in multiple sclerosis lesions
18. Lipoprotein-associated phospholipase A2 activity, ferritin levels, metabolic syndrome, and 10-year cardiovascular and non-cardiovascular mortality: results from the Bruneck study
19. You are right too!
20. Cardiac valvular abnormalities are frequent in systemic lupus erythematosus patients with manifest arterial disease
21. Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy.
22. Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation precede monocyte recruitment into early atherosclerotic lesions.
23. Pathogenic antibodies inhibit the binding of apolipoproteins to megalin/gp330 in passive Heymann nephritis.
24. Excess iron induces hepatic oxidative stress and transforming growth factor ?1 in genetic hemochromatosis
25. Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma.
26. Antiphospholipid antibodies are directed against epitopes of oxidized phospholipids. Recognition of cardiolipin by monoclonal antibodies to epitopes of oxidized low density lipoprotein.
27. The 94- to 97-kDa mouse macrophage membrane protein that recognizes oxidized low density lipoprotein and phosphatidylserine-rich liposomes is identical to macrosialin, the mouse homologue of human CD68.
28. Lipoperoxides in LDL incubated with fibroblasts that overexpress 15-lipoxygenase.
29. T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein.
30. Immunization of low density lipoprotein (LDL) receptor-deficient rabbits with homologous malondialdehyde-modified LDL reduces atherogenesis.
31. Proteinuria in passive Heymann nephritis is associated with lipid peroxidation and formation of adducts on type IV collagen.
32. Altered apolipoprotein B metabolism in very low density lipoprotein from lovastatin-treated guinea pigs.
33. ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum.
34. Rabbit and human atherosclerotic lesions contain IgG that recognizes epitopes of oxidized LDL.
35. Abundant expression of apoprotein E by macrophages in human and rabbit atherosclerotic lesions.
36. Murine models for study of lipoprotein metabolism and atherosclerosis.
37. Effect of dietary antioxidant combinations in humans. Protection of LDL by vitamin E but not by beta-carotene.
38. Comparison of supplementation of RRR-alpha-tocopherol and racemic alpha-tocopherol in humans. Effects on lipid levels and lipoprotein susceptibility to oxidation.
39. Effects of oleate-rich and linoleate-rich diets on the susceptibility of low density lipoprotein to oxidative modification in mildly hypercholesterolemic subjects.
40. Role of oxidised low density lipoprotein in atherogenesis
41. Monoclonal antibodies against LDL further enhance macrophage uptake of LDL aggregates.
42. Aminoguanidine inhibits oxidative modification of low density lipoprotein protein and the subsequent increase in uptake by macrophage scavenger receptors.
43. Effect of probucol dosage on plasma lipid and lipoprotein levels and on protection of low density lipoprotein against in vitro oxidation in humans.
44. The Role of Oxidized Low-Density Lipoproteins in the Pathogenesis of Atherosclerosis
45. Role of oxidized low density lipoprotein in atherogenesis.
46. Macrophages and smooth muscle cells express lipoprotein lipase in human and rabbit atherosclerotic lesions.
47. Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions.
48. Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts.
49. Macrophage-derived foam cells freshly isolated from rabbit atherosclerotic lesions degrade modified lipoproteins, promote oxidation of low-density lipoproteins, and contain oxidation-specific lipid-protein adducts.
50. Malondialdehyde and 4-hydroxynonenal protein adducts in plasma and liver of rats with iron overload.
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