Search

Your search keyword '"Weber-Levine, Carly"' showing total 43 results
Start Over Author "Weber-Levine, Carly" Publication Year Range Last 50 years
43 results on '"Weber-Levine, Carly"'

5. Early versus late surgical decompression for patients with acute traumatic central cord syndrome: a systematic review and meta-analysis

Author

Sattari, Shahab Aldin, Antar, Albert, Theodore, John N., Hersh, Andrew M., Al-Mistarehi, Abdel-Hameed, Davidar, A. Daniel, Weber-Levine, Carly, Azad, Tej D., Yang, Wuyang, Feghali, James, Xu, Risheng, Manbachi, Amir, Lubelski, Daniel, Bettegowda, Chetan, Chang, Louis, Witham, Timothy, Belzberg, Allan, and Theodore, Nicholas

Published
2024
Full Text
View/download PDF

8. 1237 The Mutational Landscape of Molecularly Defined Oligodendrogliomas

Author

Weber-Levine, Carly, primary, Rakovec, Maureen, additional, Jiang, Kelly, additional, Kalluri, Anita, additional, Raj, Divyaansh, additional, Parker, Megan, additional, Materi, Joshua, additional, Sepehri, Sadra, additional, Ferres, Abel, additional, Schreck, Karisa C., additional, Aldecoa, Iban, additional, Lucas, Calixto-Hope, additional, Redmond, Kristin, additional, Holdhoff, Matthias, additional, Sair, Haris, additional, and Brem, Henry, additional

Published
2024
Full Text
View/download PDF

9. 380 2021 WHO Grading Scheme Provides Minimal Incremental Improvement in Prognostic Stratification of a Retrospective IDH-Mutant Astrocytoma Cohort Compared to 2016 WHO Grading Scheme

Author

Kalluri, Anita, primary, Myneni, Saket, additional, Parker, Megan, additional, Weber-Levine, Carly, additional, Arshad, Umar, additional, Shaw, Jacob, additional, Sarlin, Samantha, additional, Rempert, Ashley, additional, Dunseath, Chloe, additional, Materi, Joshua, additional, Raj, Divyaansh, additional, Rincon Torroella, Jordina N., additional, Ye, Xiaobu, additional, Lucas, Calixto-Hope, additional, and Bettegowda, Chetan, additional

Published
2024
Full Text
View/download PDF

10. 462 Stem Cell-Loaded Implantable Intrathecal Bioreactors for the Treatment of Spinal Cord Injury: A Porcine Model Pilot Study

Author

Jiang, Kelly, primary, Saberi, Amir, additional, Weber-Levine, Carly, additional, Bhimreddy, Meghana, additional, Menta, Arjun, additional, Routkevich, Denis, additional, Davidar, Daniel, additional, Quiroz, Victor, additional, Hersh, Andrew, additional, Luksik, Andrew, additional, Khalsa, Siri, additional, Liu, Ann, additional, Judy, Brendan F., additional, Manbachi, Amir, additional, Doloff, Joshua, additional, and Theodore, Nicholas, additional

Published
2024
Full Text
View/download PDF

18. Exoscope use in spine surgery: a systematic review of applications, benefits, and limitations

Author

Vattipally, Vikas N., primary, Jiang, Kelly, additional, Weber-Levine, Carly, additional, Rosin, Richard, additional, Davidar, A. Daniel, additional, Hersh, Andrew M., additional, Khalifeh, Jawad, additional, Ahmed, A. Karim, additional, Azad, Tej D., additional, Ashayeri, Kimberly, additional, Lubelski, Daniel, additional, Mukherjee, Debraj, additional, Huang, Judy, additional, and Theodore, Nicholas, additional

Published
2023
Full Text
View/download PDF

21. Spinal Cord Injury

Author

Hersh, Andrew M., primary, Weber-Levine, Carly, additional, Jiang, Kelly, additional, and Theodore, Nicholas, additional

Published
2023
Full Text
View/download PDF

23. Early vs late surgical decompression for patients with acute traumatic central cord syndrome: a systematic review and meta-analysis

Author

Sattari, Shahab Aldin, primary, Antar, Albert, additional, Theodore, John N., additional, Hersh, Andrew M., additional, Al-Mistarehi, Abdel-Hameed, additional, Davidar, A. Daniel, additional, Weber-Levine, Carly, additional, Azad, Tej D., additional, Yang, Wuyang, additional, Feghali, James, additional, Xu, Risheng, additional, Manbachi, Amir, additional, Lubelski, Daniel, additional, Bettegowda, Chetan, additional, Chang, Louis, additional, Witham, Timothy, additional, Belzberg, Allan, additional, and Theodore, Nicholas, additional

Published
2023
Full Text
View/download PDF

24. Quantification of Spinal Cord Microvascular Perfusion utilizing Ultrasound

Author

Leadingham, Kelley M. Kempski, primary, Routkevitch, Denis, additional, Hersh, Andrew M., additional, Kerensky, Max, additional, Abramson, Haley G., additional, Weber-Levine, Carly, additional, Robinson, Kayla, additional, Jiang, Kelly, additional, Judy, Brendan, additional, Perdomo-Pantoja, Alexander, additional, Theodore, Nicholas, additional, and Manbachi, Amir, additional

Published
2023
Full Text
View/download PDF

25. ASXL1 inactivation and reduced H3K27me3 across central nervous system tumors.

Author

Zhang, Kevin Y., Parker, Megan, Weber-Levine, Carly, Kalluri, Anita, Gonzalez-Gomez, Ignacio, Raabe, Eric, Dudley, Jonathan C., Gocke, Christopher, Lin, Ming-Tseh, Zou, Ying, Sherief, Mohamed, Kamson, David O., Holdhoff, Matthias, Mukherjee, Debraj, Croog, Victoria, Schreck, Karisa C., Rincon-Torroella, Jordina, Bettegowda, Chetan, Eberhart, Charles G., and Bale, Tejus

Published
2024
Full Text
View/download PDF

27. Robot-assisted screw fixation in a cadaver utilizing magnetic resonance imaging–based synthetic computed tomography: toward radiation-free spine surgery. Illustrative case

Author

Davidar, A. Daniel, primary, Judy, Brendan F., additional, Hersh, Andrew M., additional, Weber-Levine, Carly, additional, Alomari, Safwan, additional, Menta, Arjun K., additional, Jiang, Kelly, additional, Bhimreddy, Meghana, additional, Hussain, Mir, additional, Crawford, Neil R., additional, Khan, Majid, additional, Gong, Gary, additional, and Theodore, Nicholas, additional

Published
2023
Full Text
View/download PDF

28. Low-Intensity Pulsed Ultrasound Neuromodulation of a Rodent's Spinal Cord Suppresses Motor Evoked Potentials

Author

Tsehay, Yohannes, primary, Zeng, Yinuo, additional, Weber-Levine, Carly, additional, Awosika, Tolulope, additional, Kerensky, Max, additional, Hersh, Andrew M., additional, Ou, Ze, additional, Jiang, Kelly, additional, Bhimreddy, Meghana, additional, Bauer, Stuart J., additional, Theodore, John N., additional, Quiroz, Victor M., additional, Suk, Ian, additional, Alomari, Safwan, additional, Sun, Junfeng, additional, Tong, Shanbao, additional, Thakor, Nitish, additional, Doloff, Joshua C., additional, Theodore, Nicholas, additional, and Manbachi, Amir, additional

Published
2023
Full Text
View/download PDF

31. Disruption of the Blood-Spinal Cord Barrier using Low-Intensity Focused Ultrasound in a Rat Model

Author

Bhimreddy, Meghana, primary, Routkevitch, Denis, primary, Hersh, Andrew M., primary, Mohammadabadi, Ali, primary, Menta, Arjun K., primary, Jiang, Kelly, primary, Weber-Levine, Carly, primary, Davidar, A. Daniel, primary, Punnoose, Joshua, primary, Kempski Leadingham, Kelley M., primary, Doloff, Joshua C., primary, Tyler, Betty, primary, Theodore, Nicholas, primary, and Manbachi, Amir, primary

Published
2023
Full Text
View/download PDF

35. Porcine Model of Spinal Cord Injury: A Systematic Review

Author

Weber-Levine, Carly, primary, Hersh, Andrew M., additional, Jiang, Kelly, additional, Routkevitch, Denis, additional, Tsehay, Yohannes, additional, Perdomo-Pantoja, Alexander, additional, Judy, Brendan F., additional, Kerensky, Max, additional, Liu, Ann, additional, Adams, Melanie, additional, Izzi, Jessica, additional, Doloff, Joshua C., additional, Manbachi, Amir, additional, and Theodore, Nicholas, additional

Published
2022
Full Text
View/download PDF

39. Automated prediction of the Thoracolumbar Injury Classification and Severity Score from CT using a novel deep learning algorithm

Author

Doerr, Sophia A., primary, Weber-Levine, Carly, additional, Hersh, Andrew M., additional, Awosika, Tolulope, additional, Judy, Brendan, additional, Jin, Yike, additional, Raj, Divyaansh, additional, Liu, Ann, additional, Lubelski, Daniel, additional, Jones, Craig K., additional, Sair, Haris I., additional, and Theodore, Nicholas, additional

Published
2022
Full Text
View/download PDF

40. Augmented Reality in Spine Surgery: A Narrative Review

Author

Hersh, Andrew, primary, Mahapatra, Smruti, additional, Weber-Levine, Carly, additional, Awosika, Tolulope, additional, Theodore, John N., additional, Zakaria, Hesham M., additional, Liu, Ann, additional, Witham, Timothy F., additional, and Theodore, Nicholas, additional

Published
2021
Full Text
View/download PDF

41. Genomic Alterations in Molecularly Defined Oligodendrogliomas.

Author

Weber-Levine C, Rakovec M, Jiang K, Kalluri A, Raj D, Parker M, Materi J, Sepehri S, Ferrés A, Schreck KC, Aldecoa I, Lucas CG, Redmond KJ, Holdhoff M, Sair HI, Weingart JD, Brem H, González Sánchez J, Ye X, Bettegowda C, and Rincon-Torroella J

Abstract

Background and Objectives: Oligodendrogliomas are defined by IDH1/2 mutation and codeletion of chromosome arms 1p/19q. Although previous studies identified CIC, FUBP1, and TERTp as frequently altered in oligodendrogliomas, the clinical relevance of these molecular signatures is unclear. Moreover, previous studies predominantly used research panels that are not readily available to providers and patients. Accordingly, we explore genomic alterations in molecularly defined oligodendrogliomas using clinically standardized next-generation sequencing (NGS) panels., Methods: A retrospective single-center study evaluated adults with pathologically confirmed IDH-mutant, 1p/19q-codeleted oligodendrogliomas diagnosed between 2005 and 2021. Genetic data from formalin-fixed, paraffin-embedded specimens were analyzed with the NGS Solid Tumor Panel at the Johns Hopkins Medical Laboratories, which tests more than 400 cancer-related genes. Kaplan-Meier plots and log-rank tests compared progression-free survival (PFS) and overall survival by variant status. χ2 tests, t-tests, and Wilcoxon rank-sum tests were used to compare clinical characteristics between genomic variant status in the 10 most frequently altered genes., Results: Two hundred and seventy-seven patients with molecularly defined oligodendrogliomas were identified, of which 95 patients had available NGS reports. Ten genes had 9 or more patients with a genomic alteration, with CIC, FUBP1, and TERTp being the most frequently altered genes (n = 60, 23, and 22, respectively). Kaplan-Meier curves showed that most genes were not associated with differences in PFS or overall survival. At earlier time points (PFS <100 months), CIC alterations conferred a reduction in PFS in patients (P = .038)., Conclusion: Our study confirms the elevated frequency of CIC, FUBP1, and TERTp alterations in molecularly defined oligodendrogliomas and suggests a potential relationship of CIC alteration to PFS at earlier time points. Understanding these genomic variants may inform prognosis or therapeutic recommendations as NGS becomes routine., (Copyright © Congress of Neurological Surgeons 2024. All rights reserved.)

Published
2024
Full Text
View/download PDF

42. Comparison of accuracy, revision, and perioperative outcomes in robot-assisted spine surgeries: systematic review and meta-analysis.

Author

MacLean L, Hersh AM, Bhimreddy M, Jiang K, Davidar AD, Weber-Levine C, Alomari S, Judy BF, Lubelski D, and Theodore N

Abstract

Objective: Pedicle screw placement guidance is critical in spinal fusions, and spinal surgery robots aim to improve accuracy and reduce complications. Current literature has yet to compare the relative merits of available robotic systems. In this review, the authors aimed to 1) assess the current state of spinal robotics literature; 2) conduct a meta-analysis of robotic performance based on accuracy, speed, and safety; and 3) offer recommendations for robotic system selection., Methods: Following PRISMA guidelines, the authors conducted a systematic literature review across PubMed, Embase, Cochrane Library, Web of Science, and Scopus as of April 28, 2022, for studies on approved robots for placing lumbar pedicle screws. Three reviewers screened and extracted data relating to the study characteristics, accuracy rate, intraoperative revisions, and reoperations. Secondary performance metrics included operative time, blood loss, and radiation exposure. The authors statistically compared the performance of the robots using a random-effects model to account for variation within and between the studies. Each robot was also compared with performance benchmarks of traditional techniques including freehand, fluoroscopic, and CT-navigated insertion. Finally, we performed a Duval and Tweedie trim-and-fill test to assess for the presence of publication bias., Results: The authors identified 46 studies, describing 4670 patients and 25,054 screws, that evaluated 4 different robotic systems: Mazor X, ROSA, ExcelsiusGPS, and Cirq. The weighted accuracy rates of Gertzbein-Robbins classification grade A or B screws were as follows: ExcelsiusGPS, 98.0%; ROSA, 98.0%; Mazor, 98.2%; and Cirq, 94.2%. No robot was significantly more accurate than the others. However, the accuracy of the ExcelsiusGPS was significantly higher than that of traditional methods, and the accuracies of the Mazor and ROSA were significantly higher than that of fluoroscopy. The intraoperative revision rates were Cirq, 0.55%; ROSA, 0.91%; Mazor, 0.98%; and ExcelsiusGPS, 1.08%. The reoperation rates were Cirq, 0.28%; ExcelsiusGPS, 0.32%; and Mazor, 0.76% (no reoperations were reported for ROSA). Operative times were similar for all robots. Both the ExcelsiusGPS and Mazor were associated with significantly less blood loss than the ROSA. The Cirq had the lowest radiation exposure. Robots tended to be more accurate and generally their use was associated with fewer reoperations and less blood loss than freehand, fluoroscopic, or CT-navigated techniques., Conclusions: Robotic platforms perform comparably based on key metrics, with high accuracy rates and low intraoperative revision and reoperation rates. The spinal robotics publication rate will continue to accelerate, and choosing a robot will depend on the context of the practice.

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results