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558 results on '"Tai, Ming-Hong"'

3. Slow skeletal muscle troponin T acts as a potential prognostic biomarker and therapeutic target for hepatocellular carcinoma

Author

Huang, Shih-Chung, Huang, Chao-Cheng, Ko, Chou-Yuan, Huang, Cheng-Yi, Liu, Ching-Han, Lee, Yung-Kuo, Chen, Tung-Yuan, Hsueh, Chao-Wen, Tzou, Shiow-Jyu, Tai, Ming-Hong, Hu, Tsung-Hui, Tsai, Ming-Chao, Lee, Wen-Chin, Ho, Yu-Cheng, Wu, Cheng-Chun, Chang, Yi-Chen, Chang, Jung-Jui, Liu, Kai-Hsi, Li, Chiao-Ching, Wen, Zhi-Hong, Chang, Chen-Lin, and Chu, Tian-Huei

Published
2023
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4. Comparison of serum WFA+‐M2BP, FIB‐4, and APRI for cirrhosis and esophageal varices prediction in hepatoma patients

Author

Lin, Ming‐Tsung, primary, Chang, Kuo‐Chin, additional, Wang, Chih‐Chi, additional, Chiu, Sherry Yueh‐Hsia, additional, Yong, Chee‐Chien, additional, Liu, Yueh‐Wei, additional, Li, Wei‐Feng, additional, Wang, Jing‐Houng, additional, Huang, Chao‐Cheng, additional, Hsiao, Chang‐Chun, additional, Tai, Ming‐Hong, additional, and Hu, Tsung‐Hui, additional

Published
2024
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6. Iodinated gadolinium-gold nanomaterial as a multimodal contrast agent for cartilage tissue imaging.

Author

Lu, Cheng-Hsiu, Lian, Wei-Shiung, Wu, Re-Wen, Lin, Yu-Han, Su, Chia-Hao, Chen, Chuan-Lin, Tai, Ming-Hong, Chen, Yu-Shan, Wang, Shao-Yu, Chen, Chao-Cheng, and Wang, Feng-Sheng

Subjects
COMPUTED tomography, CONTRAST media, DRUG carriers, ATOMIC number, PATHOLOGICAL physiology
Abstract

Cartilage damage, a common cause of osteoarthritis, requires medical imaging for accurate diagnosis of pathological changes. However, current instruments can acquire limited imaging information due to sensitivity and resolution issues. Therefore, multimodal imaging is considered an alternative strategy to provide valuable images and analyzes from different perspectives. Among all biomaterials, gold nanomaterials not only exhibit outstanding benefits as drug carriers, in vitro diagnostics, and radiosensitizers, but are also widely used as contrast agents, particularly for tumors. However, their potential for imaging cartilage damage is rarely discussed. In this study, we developed a versatile iodinated gadolinium-gold nanomaterial, AuNC@BSA-Gd-I, and its radiolabeled derivative, AuNC@BSA-Gd-131I, for cartilage detection. With its small size, negative charge, and multimodal capacities, the probe can penetrate damaged cartilage and be detected or visualized by computed tomography, MRI, IVIS, and gamma counter. Additionally, the multimodal imaging potential of AuNC@BSA-Gd-I was compared to current multifunctional gold nanomaterials containing similar components, including anionic AuNC@BSA, AuNC@BSA-I, and AuNC@BSA-Gd as well as cationic AuNC@CBSA. Due to their high atomic numbers and fluorescent emission, AuNC@BSA nanomaterials could provide fundamental multifunctionality for imaging. By further modifying AuNC@BSA with additional imaging materials, their application could be extended to various types of medical imaging instruments. Nonetheless, our findings showed that each of the current nanomaterials exhibited excellent abilities for imaging cartilage with their predominant imaging modalities, but their versatility was not comparable to that of AuNC@BSA-Gd-I. Thus, AuNC@BSA-Gd-I could be served as a valuable tool in multimodal imaging strategies for cartilage assessment. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Comparison of serum WFA+‐M2BP, FIB‐4, and APRIfor cirrhosis and esophageal varices prediction in hepatoma patients

Author

Lin, Ming‐Tsung, Chang, Kuo‐Chin, Wang, Chih‐Chi, Chiu, Sherry Yueh‐Hsia, Yong, Chee‐Chien, Liu, Yueh‐Wei, Li, Wei‐Feng, Wang, Jing‐Houng, Huang, Chao‐Cheng, Hsiao, Chang‐Chun, Tai, Ming‐Hong, and Hu, Tsung‐Hui

Abstract

Wisteria floribunda agglutinin‐positive Mac‐2 binding protein (WFA+‐M2BP) is a novel biomarker for evaluating hepatic fibrosis and hepatocellular carcinoma (HCC) development. However, no previous study has compared its diagnostic accuracy with that of FIB‐4 or APRI nor explored its clinical application for predicting esophageal varices bleeding in HCC patients. In this study, we explored these biomarkers and compared their clinical roles. Total 459 HCC patients who underwent curative operation were enrolled in this study. WFA+‐M2BP level was evaluated using stored blood samples that were collected during surgery, and liver fibrosis was diagnosed based on findings of surgical specimen analysis. Esophageal or gastric varices were evaluated in 207 patients who underwent esophagogastroduodenoscopy (EGD). The correlation between the markers was also determined. Our study showed WFA+‐M2BP level, FIB‐4, and APRI had a similar high accuracy of approximately 73% for liver cirrhosis diagnosis. Their levels were significantly correlated with the liver fibrosis stage (p< .0001). WFA+‐M2BP level, FIB‐4, and APRI also had high diagnostic accuracy for varices formation (accuracy, 76.8%–80.2%) and high predictive accuracy for variceal bleeding (accuracy, 73.9%–76.3%). The correlation between WFA+‐M2BP level and FIB‐4 or between WFA+‐M2BP level and APRI was weak (Pearson r< 0.5, p< .0001) but that between FIB‐4 and APRI was very strong (Pearson r> 0.9, p< .0001). Our study demonstrated WFA+‐M2BP level, FIB‐4, and APRI have all shown to be very useful noninvasive methods for evaluating liver fibrosis and predicting esophageal varices bleeding to avoid risky liver biopsy and EGD examination.

Published
2024
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20. Supplementary Figure 2 from Downregulation of Hepatoma-Derived Growth Factor Contributes to Retarded Lung Metastasis via Inhibition of Epithelial–Mesenchymal Transition by Systemic POMC Gene Delivery in Melanoma

Author

Tsai, Han-En, primary, Liu, Guei-Sheung, primary, Kung, Mei-Lang, primary, Liu, Li-Feng, primary, Wu, Jian-Ching, primary, Tang, Chia-Hua, primary, Huang, Ching-Hui, primary, Chen, San-Cher, primary, Lam, Hing-Chung, primary, Wu, Chieh-Shan, primary, and Tai, Ming-Hong, primary

Published
2023
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21. Supplementary Figure 1 from Downregulation of Hepatoma-Derived Growth Factor Contributes to Retarded Lung Metastasis via Inhibition of Epithelial–Mesenchymal Transition by Systemic POMC Gene Delivery in Melanoma

Author

Tsai, Han-En, primary, Liu, Guei-Sheung, primary, Kung, Mei-Lang, primary, Liu, Li-Feng, primary, Wu, Jian-Ching, primary, Tang, Chia-Hua, primary, Huang, Ching-Hui, primary, Chen, San-Cher, primary, Lam, Hing-Chung, primary, Wu, Chieh-Shan, primary, and Tai, Ming-Hong, primary

Published
2023
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22. Supplementary Figure Legend from Downregulation of Hepatoma-Derived Growth Factor Contributes to Retarded Lung Metastasis via Inhibition of Epithelial–Mesenchymal Transition by Systemic POMC Gene Delivery in Melanoma

Author

Tsai, Han-En, primary, Liu, Guei-Sheung, primary, Kung, Mei-Lang, primary, Liu, Li-Feng, primary, Wu, Jian-Ching, primary, Tang, Chia-Hua, primary, Huang, Ching-Hui, primary, Chen, San-Cher, primary, Lam, Hing-Chung, primary, Wu, Chieh-Shan, primary, and Tai, Ming-Hong, primary

Published
2023
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23. Supplementary Figure 3 from Downregulation of Hepatoma-Derived Growth Factor Contributes to Retarded Lung Metastasis via Inhibition of Epithelial–Mesenchymal Transition by Systemic POMC Gene Delivery in Melanoma

Author

Tsai, Han-En, primary, Liu, Guei-Sheung, primary, Kung, Mei-Lang, primary, Liu, Li-Feng, primary, Wu, Jian-Ching, primary, Tang, Chia-Hua, primary, Huang, Ching-Hui, primary, Chen, San-Cher, primary, Lam, Hing-Chung, primary, Wu, Chieh-Shan, primary, and Tai, Ming-Hong, primary

Published
2023
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24. Supplementary Figure 3 from Extracellular Visfatin-Promoted Malignant Behavior in Breast Cancer Is Mediated Through c-Abl and STAT3 Activation

Author

Hung, Amos C., primary, Lo, Steven, primary, Hou, Ming-Feng, primary, Lee, Yi-Chen, primary, Tsai, Chun-Hao, primary, Chen, Yuan-Yin, primary, Liu, Wangta, primary, Su, Yu-Han, primary, Lo, Yi-Hsuan, primary, Wang, Chie-Hong, primary, Wu, Shiou-Chen, primary, Hsieh, Ya-Ching, primary, Hu, Stephen Chu-Sung, primary, Tai, Ming-Hong, primary, Wang, Yun-Ming, primary, and Yuan, Shyng-Shiou F., primary

Published
2023
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25. supplemental figure legend from Extracellular Visfatin-Promoted Malignant Behavior in Breast Cancer Is Mediated Through c-Abl and STAT3 Activation

Author

Hung, Amos C., primary, Lo, Steven, primary, Hou, Ming-Feng, primary, Lee, Yi-Chen, primary, Tsai, Chun-Hao, primary, Chen, Yuan-Yin, primary, Liu, Wangta, primary, Su, Yu-Han, primary, Lo, Yi-Hsuan, primary, Wang, Chie-Hong, primary, Wu, Shiou-Chen, primary, Hsieh, Ya-Ching, primary, Hu, Stephen Chu-Sung, primary, Tai, Ming-Hong, primary, Wang, Yun-Ming, primary, and Yuan, Shyng-Shiou F., primary

Published
2023
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26. Supplemental Tables from Extracellular Visfatin-Promoted Malignant Behavior in Breast Cancer Is Mediated Through c-Abl and STAT3 Activation

Author

Hung, Amos C., primary, Lo, Steven, primary, Hou, Ming-Feng, primary, Lee, Yi-Chen, primary, Tsai, Chun-Hao, primary, Chen, Yuan-Yin, primary, Liu, Wangta, primary, Su, Yu-Han, primary, Lo, Yi-Hsuan, primary, Wang, Chie-Hong, primary, Wu, Shiou-Chen, primary, Hsieh, Ya-Ching, primary, Hu, Stephen Chu-Sung, primary, Tai, Ming-Hong, primary, Wang, Yun-Ming, primary, and Yuan, Shyng-Shiou F., primary

Published
2023
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27. Supplementary Figure 6 from Extracellular Visfatin-Promoted Malignant Behavior in Breast Cancer Is Mediated Through c-Abl and STAT3 Activation

Author

Hung, Amos C., primary, Lo, Steven, primary, Hou, Ming-Feng, primary, Lee, Yi-Chen, primary, Tsai, Chun-Hao, primary, Chen, Yuan-Yin, primary, Liu, Wangta, primary, Su, Yu-Han, primary, Lo, Yi-Hsuan, primary, Wang, Chie-Hong, primary, Wu, Shiou-Chen, primary, Hsieh, Ya-Ching, primary, Hu, Stephen Chu-Sung, primary, Tai, Ming-Hong, primary, Wang, Yun-Ming, primary, and Yuan, Shyng-Shiou F., primary

Published
2023
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28. Supplementary Figure 2 from Extracellular Visfatin-Promoted Malignant Behavior in Breast Cancer Is Mediated Through c-Abl and STAT3 Activation

Author

Hung, Amos C., primary, Lo, Steven, primary, Hou, Ming-Feng, primary, Lee, Yi-Chen, primary, Tsai, Chun-Hao, primary, Chen, Yuan-Yin, primary, Liu, Wangta, primary, Su, Yu-Han, primary, Lo, Yi-Hsuan, primary, Wang, Chie-Hong, primary, Wu, Shiou-Chen, primary, Hsieh, Ya-Ching, primary, Hu, Stephen Chu-Sung, primary, Tai, Ming-Hong, primary, Wang, Yun-Ming, primary, and Yuan, Shyng-Shiou F., primary

Published
2023
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29. Supplementary Figure 5 from Extracellular Visfatin-Promoted Malignant Behavior in Breast Cancer Is Mediated Through c-Abl and STAT3 Activation

Author

Hung, Amos C., primary, Lo, Steven, primary, Hou, Ming-Feng, primary, Lee, Yi-Chen, primary, Tsai, Chun-Hao, primary, Chen, Yuan-Yin, primary, Liu, Wangta, primary, Su, Yu-Han, primary, Lo, Yi-Hsuan, primary, Wang, Chie-Hong, primary, Wu, Shiou-Chen, primary, Hsieh, Ya-Ching, primary, Hu, Stephen Chu-Sung, primary, Tai, Ming-Hong, primary, Wang, Yun-Ming, primary, and Yuan, Shyng-Shiou F., primary

Published
2023
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30. Supplementary Figure 1 from Extracellular Visfatin-Promoted Malignant Behavior in Breast Cancer Is Mediated Through c-Abl and STAT3 Activation

Author

Hung, Amos C., primary, Lo, Steven, primary, Hou, Ming-Feng, primary, Lee, Yi-Chen, primary, Tsai, Chun-Hao, primary, Chen, Yuan-Yin, primary, Liu, Wangta, primary, Su, Yu-Han, primary, Lo, Yi-Hsuan, primary, Wang, Chie-Hong, primary, Wu, Shiou-Chen, primary, Hsieh, Ya-Ching, primary, Hu, Stephen Chu-Sung, primary, Tai, Ming-Hong, primary, Wang, Yun-Ming, primary, and Yuan, Shyng-Shiou F., primary

Published
2023
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31. Supplementary Figure 4 from Extracellular Visfatin-Promoted Malignant Behavior in Breast Cancer Is Mediated Through c-Abl and STAT3 Activation

Author

Hung, Amos C., primary, Lo, Steven, primary, Hou, Ming-Feng, primary, Lee, Yi-Chen, primary, Tsai, Chun-Hao, primary, Chen, Yuan-Yin, primary, Liu, Wangta, primary, Su, Yu-Han, primary, Lo, Yi-Hsuan, primary, Wang, Chie-Hong, primary, Wu, Shiou-Chen, primary, Hsieh, Ya-Ching, primary, Hu, Stephen Chu-Sung, primary, Tai, Ming-Hong, primary, Wang, Yun-Ming, primary, and Yuan, Shyng-Shiou F., primary

Published
2023
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32. Independent Signaling of Hepatoma Derived Growth Factor and Tumor Necrosis Factor-Alpha in Human Gastric Cancer Organoids Infected by Helicobacter pylori

Author

Wuputra, Kenly, primary, Ku, Chia-Chen, additional, Pan, Jia-Bin, additional, Liu, Chung-Jung, additional, Kato, Kohsuke, additional, Lin, Ying-Chu, additional, Liu, Yi-Chang, additional, Lin, Chang-Shen, additional, Hsiao, Michael, additional, Tai, Ming-Hong, additional, Chong, Inn-Wen, additional, Hu, Huang-Ming, additional, Kuo, Chao-Hung, additional, Wu, Deng-Chyang, additional, and Yokoyama, Kazunari K., additional

Published
2023
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40. Leukocyte cell-derived chemotaxin 2 regulates epithelial-mesenchymal transition and cancer stemness in hepatocellular carcinoma

Author

Chu, Tian-Huei, primary, Ko, Chou-Yuan, additional, Tai, Po-Han, additional, Chang, Yi-Chen, additional, Huang, Chao-Cheng, additional, Wu, Tung-Yang, additional, Chan, Hoi-Hung, additional, Wu, Ping-Hsuan, additional, Weng, Chien-Hui, additional, Lin, Yu-Wei, additional, Kung, Mei-Lang, additional, Fang, Cheng-Chieh, additional, Wu, Jian-Ching, additional, Wen, Zhi-Hong, additional, Lee, Yung-Kuo, additional, Hu, Tsung-Hui, additional, and Tai, Ming-Hong, additional

Published
2022
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47. DLK2 Acts as a Potential Prognostic Biomarker for Clear Cell Renal Cell Carcinoma Based on Bioinformatics Analysis

Author

Lee, Man-Gang, primary, Lee, Yung-Kuo, additional, Huang, Shih-Chung, additional, Chang, Chen-Lin, additional, Ko, Chou-Yuan, additional, Lee, Wen-Chin, additional, Chen, Tung-Yuan, additional, Tzou, Shiow-Jyu, additional, Huang, Cheng-Yi, additional, Tai, Ming-Hong, additional, Lin, Yu-Wei, additional, Kung, Mei-Lang, additional, Tsai, Ming-Chao, additional, Chen, Yung-Lung, additional, Chang, Yi-Chen, additional, Wen, Zhi-Hong, additional, Huang, Chao-Cheng, additional, and Chu, Tian-Huei, additional

Published
2022
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