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474 results on '"Stankovic, I"'

1. Photoproduction of $K^+K^-$ meson pairs on the proton

Author

Lombardo, S., Battaglieri, M., Celentano, A., D'Angelo, A., De Vita, R., Filippi, A., Glazier, D., Hughes, S. M., Mathieu, V., Rizzo, A., Santopinto, E., Stankovic, I., Szczepaniak, A. P., Watts, D., Zana, L., and Collaboration, the CLAS

Subjects
High Energy Physics - Experiment, Nuclear Experiment
Abstract

The exclusive reaction $\gamma p \to p K^+ K^-$ was studied in the photon energy range $3.0 - 3.8 \mbox{ GeV}$ and momentum transfer range $0.6<-t<1.3 \mbox{ GeV}^2$. Data were collected with the CLAS detector at the Thomas Jefferson National Accelerator Facility. In this kinematic range the integrated luminosity was approximately 20 pb$^{-1}$. The reaction was isolated by detecting the $K^+$ and the proton in CLAS, and reconstructing the $K^-$ via the missing-mass technique. Moments of the di-kaon decay angular distributions were extracted from the experimental data. Besides the dominant contribution of the $\phi$ meson in the $P$-wave, evidence for $S-P$ interference was found. The differential production cross sections $d\sigma/dt$ for individual waves in the mass range of the $\phi$ resonance were extracted and compared to predictions of a Regge-inspired model. This is the first time the $t$-dependent cross section of the $S$-wave contribution to the elastic $K^+K^-$ photoproduction has been measured., Comment: arXiv admin note: text overlap with arXiv:0907.1021

Published
2018
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2. Semi-Inclusive $\pi_0$ target and beam-target asymmetries from 6 GeV electron scattering with CLAS

Author

Jawalkar, S., Koirala, S., Avakian, H., Bosted, P., Griffioen, K. A., Keith, C., Kuhn, S. E., Adhikari, K. P., Adhikari, S., Adikaram, D., Akbar, Z., Amaryan, M. J., Pereira, S. Anefalos, Ball, J., Baltzell, N. A., Battaglieri, M., Batourine, V., Bedlinskiy, I., Biselli, A. S., Boiarinov, S., Briscoe, W. J., Brock, J., Brooks, W. K., Bultmann, S., Burkert, V. D., Cao, Frank Thanh, Carlin, C., Carman, D. S., Celentano, A., Charles, G., Chetry, T., Ciullo, G., Clark, L., Colaneri, L., Cole, P. L., Contalbrigo, M., Cortes, O., Crede, V., D'Angelo, A., Dashyan, N., De Vita, R., De Sanctis, E., Defurne, M., Deur, A., Djalali, C., Ddoge, G., Dupre, R., Egiyan, H., Alaoui, A. El, Fassi, L. El, Elouadrhiri, L., Eugenio, P., Fedotov, G., Fegan, S., Fersch, R., Filippi, A., Fleming, J. A., Forest, T. A., Fradi, A., Garcon, M., Ghandilyan, Y., Gilfoyle, G. P., Giovanetti, K. L., Girod, F. X., Gleason, C., Gohn, W., Golovatch, E., Gothe, R. W., Guidal, M., Guler, N., Guo, L., Hakobyan, H., Hanretty, C., Harrison, N., Hattawy, M., Heddle, D., Hicks, K., Hollis, G., Holtrop, M., Hughes, S. M., Ilieva, Y., Ireland, D. G., Ishkhanov, B. S., Isupov, E. L., Jenkins, D., Jiang, H., Joo, K., Joosten, S., Keller, D., Khachatryan, G., Khachatryan, M., Khandaker, M., Kim, A., Kim, W., Klein, A., Klein, F. J., Kubarovsky, V., Kuleshov, S. V., Lanza, L., Lenisa, P., Livingston, K., Lu, H. Y., MacGregor, I . J . D., Markov, N., Mayer, M., McCracken, M. E., McKinnon, B., Meyer, C. A., Mineeva, T., Mirazita, M., Mokeev, V., Montgomery, R. A., Movsisyan, A, Camacho, C. Munoz, Nadel-Turonski, P., Net, L. A., Niccolai, S., Niculescu, G., Niculescu, I., Osipenko, M., Ostrovidov, A. I., Paremuzyan, R., Park, K., Pasyuk, E., Phelps, E., Phelps, W., Pierce, J., Pisano, S., Pogorelko, O., Price, J. W., Prok, Y., Protopopescu, D., Raue, B. A., Ripani, M., Riser, D., Rizzo, A., Rosner, G., Rossi, P., Sabatie, F., Salgado, C., Schumacher, R. A., Seder, E., Sharabian, Y. G., Simonyan, A., Skorodumina, Iu., Smith, G. D., Sober, D. I., Sokhan, D., Sparveris, N., Stankovic, I., Strauch, S., Taiuti, M., Ungaro, M., Voskanyan, H., Voutier, E., Walford, N. K., Watts, D. P., Wei, X., Weinstein, L. B., Wood, M. H., Zachariou, N., Zhang, J., and Zhao, Z. W.

Subjects
Nuclear Experiment, High Energy Physics - Phenomenology
Abstract

We present precision measurements of the target and beam-target spin asymmetries from neutral pion electroproduction in deep-inelastic scattering (DIS) using the CEBAF Large Acceptance Spectrometer (CLAS) at Jefferson Lab. We scattered 6-GeV, longitudinally polarized electrons off longitudinally polarized protons in a cryogenic $^{14}$NH$_3$ target, and extracted double and single target spin asymmetries for $ep\rightarrow e^\prime\pi^0X$ in multidimensional bins in four-momentum transfer ($1.0

Published
2017
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3. Photon beam asymmetry $\Sigma$ in the reaction $\vec{\gamma} p \to p \omega$ for $E_\gamma$ = 1.152 to 1.876 GeV

Author

CLAS Collaboration, Collins, P., Ritchie, B. G., Dugger, M., Klein, F. J., Anisovich, A. V., Klempt, E., Nikonov, V. A., Sarantsev, A., Adhikari, K. P., Adhikari, S., Adikaram, D., Akbar, Z., Pereira, S. Anefalos, Avakian, H., Ball, J., Baltzell, N. A., Bashkanov, M., Battaglieri, M., Batourine, V., Bedlinskiy, I., Biselli, A. S., Boiarinov, S., Briscoe, W. J., Brooks, W. K., Burkert, V. D., Cao, Frank Thanh, Cao, T., Carman, D. S., Celentano, A., Charles, G., Chetry, T., Ciullo, G., Clark, L., Cole, P. L., Contalbrigo, M., Cortes, O., Crede, V., Dashyan, N., De Vita, R., De Sanctis, E., Defurne, M., Deur, A., Djalali, C., Dupre, R., Egiyan, H., Alaoui, A. El, Fassi, L. El, Eugenio, P., Fedotov, G., Filippi, A., Fleming, J. A., Ghandilyan, Y., Gilfoyle, G. P., Giovanetti, K. L., Girod, F. X., Glazier, D. I., Gleason, C., Golovatch, E., Gothe, R. W., Griffioen, K. A., Guidal, M., Hafidi, K., Hakobyan, H., Hanretty, C., Harrison, N., Hattawy, M., Heddle, D., Hicks, K., Hollis, G., Holtrop, M., Hughes, S. M., Ilieva, Y., Ireland, D. G., Ishkhanov, B. S., Isupov, E. L., Jenkins, D., Jiang, H., Jo, H. S., Joosten, S., Keller, D., Khachatryan, G., Khachatryan, M., Khandaker, M., Kim, A., Kim, W., Klein, A., Kubarovsky, V., Kuleshov, S. V., Lanza, L., Lenisa, P., Livingston, K., MacGregor, I. J. D., Markov, N., McKinnon, B., Meyer, C. A., Meziani, Z. E., Mineeva, T., Mokeev, V., Montgomery, R. A., Movsisyan, A., Munevar, E., Camacho, C. Munoz, Nadel-Turonski, P., Net, L. A., Niccolai, S., Niculescu, G., Niculescu, I., Osipenko, M., Ostrovidov, A. I., Paolone, M., Paremuzyan, R., Park, K., Pasyuk, E., Phelps, W., Pisano, S., Pogorelko, O., Price, J. W., Procureur, S., Prok, Y., Protopopescu, D., Raue, B. A., Ripani, M., Rizzo, A., Rosner, G., Sabatie, F., Salgado, C., Schumacher, R. A., Sharabian, Y. G., Simonyan, A., Skorodumina, Iu., Smith, G. D., Sober, D. I., Sokhan, D., Sparveris, N., Stankovic, I., Stepanyan, S., Strakovsky, I. I., Strauch, S., Taiuti, M., Ungaro, M., Voskanyan, H., Voutier, E., Walford, N. K., Watts, D. P., Wei, X., Wood, M. H., Zachariou, N., Zhang, J., and Zhao, Z. W.

Subjects
Nuclear Experiment
Abstract

Photon beam asymmetry $\Sigma$ measurements for $\omega$ photoproduction in the reaction $\vec{\gamma} p \to \omega p$ are reported for photon energies from 1.152 to 1.876 GeV. Data were taken using a linearly-polarized tagged photon beam, a cryogenic hydrogen target, and the CLAS spectrometer in Hall B at Jefferson Lab. The measurements obtained markedly increase the size of the database for this observable, extend coverage to higher energies, and resolve discrepancies in previously published data. Comparisons of these new results with predictions from a chiral-quark-based model and from a dynamical coupled-channels model indicate the importance of interferences between $t$-channel meson exchange and $s$- and $u$-channel contributions, underscoring sensitivity to the nucleon resonances included in those descriptions. Comparisons with the Bonn-Gatchina partial-wave analysis indicate the $\Sigma$ data reported here help to fix the magnitudes of the interference terms between the leading amplitudes in that calculation (Pomeron exchange and the resonant portion of the $J^P=3/2^+$ partial wave), as well as the resonant portions of the smaller partial waves with $J^P$= $1/2^-$, $3/2^-$, and $5/2^+$., Comment: 10 pages, 3 figures

Published
2017
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4. Differential Cross Section Measurements for $\gamma n\to\pi^-p$ Above the First Nucleon Resonance Region

Author

Mattione, P. T., Carman, D. S., Strakovsky, I. I., Workman, R. L., Kudryavtsev, A. E., Svarc, A., Tarasov, V. E., Adhikari, K. P., Adhikari, S., Adikaram, D., Akbar, Z., Pereira, S. Anefalos, Ball, J., Baltzell, N. A., Bashkanov, M., Battaglieri, M., Batourine, V., Bedlinskiy, I., Biselli, A. S., Boiarinov, S., Briscoe, W. J., Burkert, V. D., Cao, T., Celentano, A., Charles, G., Chetry, T., Ciullo, G., Clark, L., Cole, P. L., Contalbrigo, M., Cortes, O., Crede, V., D'Angelo, A., Dashyan, N., De Vita, R., De Sanctis, E., Defurne, M., Deur, A., Djalali, C., Dugger, M., Dupre, R., Egiyan, H., Alaoui, A. El, Fassi, L. El, Eugenio, P., Fedotov, G., Fersch, R., Filippi, A., Fleming, J. A., Fradi, A., Ghandilyan, Y., Gilfoyle, G. P., Giovanetti, K. L., Girod, F. X., Gleason, C., Golovatch, E., Gothe, R. W., Griffioen, K. A., Guidal, M., Hafidi, K., Hakobyan, H., Hanretty, C., Harrison, N., Hattawy, M., Heddle, D., Hicks, K., Hollis, G., Holtrop, M., Hughes, S. M., Ilieva, Y., Ireland, D. G., Ishkhanov, B. S., Isupov, E. L., Jenkins, D., Jiang, H., Jo, H. S., Joo, K., Joosten, S., Keller, D., Khachatryan, G., Khachatryan, M., Khandaker, M., Kim, A., Kim, W., Klein, A., Klein, F. J., Kubarovsky, V., Kuleshov, S. V., Lanza, L., Lenisa, P., Livingston, K., MacGregor, I. J. D., Markov, N., McKinnon, B., Meyer, C. A., Meziani, Z. E., Mineeva, T., Mokeev, V., Montgomery, R. A., Movsisyan, A, Camacho, C. Munoz, Murdoch, G., Nadel-Turonski, P., Net, L. A., Niccolai, S., Niculescu, G., Niculescu, I., Osipenko, M., Ostrovidov, A. I., Paolone, M., Paremuzyan, R., Park, K., Pasyuk, E., Phelps, W., Pisano, S., Pogorelko, O., Price, J. W., Procureur, S., Prok, Y., Protopopescu, D., Raue, B. A., Ripani, M., Ritchie, B. G., Rizzo, A., Rosner, G., Sabatié, F., Salgado, C., Schumacher, R. A., Sharabian, Y. G., Simonyan, A., Skorodumina, Iu., Smith, G. D., Sokhan, D., Sparveris, N., Stankovic, I., Stepanyan, S., Strauch, S., Taiuti, M., Ungaro, M., Voskanyan, H., Voutier, E., Walford, N. K., Watts, D, Wei, X., Wood, M. H., Zachariou, N., Zhang, J., and Zhao, Z. W.

Subjects
Nuclear Experiment
Abstract

The quasi-free $\gamma d\to\pi^{-}p(p)$ differential cross section has been measured with CLAS at photon beam energies $E_\gamma$ from 0.445 GeV to 2.510 GeV (corresponding to $W$ from 1.311 GeV to 2.366 GeV) for pion center-of-mass angles $\cos\theta_\pi^{c.m.}$ from -0.72 to 0.92. A correction for final state interactions has been applied to this data to extract the $\gamma n\to\pi^-p$ differential cross sections. These cross sections are quoted in 8428 $(E_\gamma,\cos\theta_\pi^{c.m.})$ bins, a factor of nearly three increase in the world statistics for this channel in this kinematic range. These new data help to constrain coupled-channel analysis fits used to disentangle the spectrum of $N^*$ resonances and extract their properties. Selected photon decay amplitudes $N^* \to \gamma n$ at the resonance poles are determined for the first time and are reported here.

Published
2017
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5. Target and beam-target spin asymmetries in exclusive pion electroproduction for $Q^2>1$ GeV$^2$. II. $e p \rightarrow e \pi^0 p$

Author

Bosted, P. E., Kim, A., Adhikari, K. P., Adikaram, D., Akbar, Z., Amaryan, M. J., Pereira, S. Anefalos, Avakian, H., Badui, R. A., Ball, J., Balossino, I., Battaglieri, M., Bedlinskiy, I., Biselli, A. S., Boiarinov, S., Briscoe, W. J., Brooks, W. K., Bültmann, S., Burkert, V. D., Cao, T., Carman, D. S., Celentano, A., Chandavar, S., Charles, G., Chetry, T., Ciullo, G., Clark, L., Colaneri, L., Cole, P. L., Contalbrigo, M., Cortes, O., Crede, V., D'Angelo, A., Dashyan, N., De Vita, R., De Sanctis, E., Deur, A., Djalali, C., Dupre, R., Egiyan, H., Alaoui, A. El, Fassi, L. El, Elouadrhiri, L., Eugenio, P., Fanchini, E., Fedotov, G., Fegan, S., Fersch, R., Filippi, A., Fleming, J. A., Forest, T. A., Fradi, A., Ghandilyan, Y., Gilfoyle, G. P., Girod, F. X., Glazier, D. I., Gohn, W., Golovatch, E., Gothe, R. W., Griffioen, K. A., Guidal, M., Guler, N., Hakobyan, H., Guo, L., Hafidi, K., Hanretty, C., Harrison, N., Hattawy, M., Heddle, D., Hicks, K., Hollis, G., Holtrop, M., Hughes, S. M., Ireland, D. G., Isupov, E. L., Jenkins, D., Jiang, H., Jo, H. S., Joo, K., Keller, D., Khachatryan, G., Khandaker, M., Kim, W., Klei, A., Klein, F. J., Koirala, S., Kubarovsky, V., Kuhn, S. E., Lanza, L., Lenisa, P., Livingston, K., Lu, H. Y., MacGregor, I. J. D., Markov, N., Mayer, M., McCracken, M. E., McKinnon, B., Mineeva, T., Mirazita, M., Mokeev, V. I., Montgomery, R. A., Movsisyan, A, Camacho, C. Munoz, Murdoch, G., Nadel-Turonski, P., Ni, A., Niccolai, S., Niculescu, G., Osipenko, M., Ostrovidov, A. I., Paolone, M., Paremuzyan, R., Park, K., Pasyuk, E., Phelps, W., Pisano, S., Pogorelko, O., Price, J. W., Prok, Y., Protopopescu, D., Puckett, A. J. R., Raue, B. A., Ripani, M., Rizzo, A., Rosner, G., Rossi, P., Roy, P., Sabatié, F., Saini, M. S., Schumacher, R. A., Seder, E., Sharabian, Y. G., Skorodumina, Iu., Smith, G. D., Sokhan, D., Sparveris, N., Stankovic, I., Stepanyan, S., Stoler, P., Strakovsky, I. I., Strauch, S., Taiuti, M., Tian, Ye, Torayev, B., Ungaro, M., Voskanyan, H., Voutier, E., Walford, N. K., Watts, D. P., Wei, X., Weinstein, L. B., Zachariou, N., Zhang, J., Zhao, Z. W., and Zonta, I.

Subjects
Nuclear Experiment
Abstract

Beam-target double-spin asymmetries and target single-spin asymmetries were measured for the exclusive $\pi^0$ electroproduction reaction $\gamma^* p \to p \pi^0$, expanding an analysis of the $\gamma^* p \to n \pi^+$ reaction from the same experiment. The results were obtained from scattering of 6 GeV longitudinally polarized electrons off longitudinally polarized protons using the CEBAF Large Acceptance Spectrometer at Jefferson Lab. The kinematic range covered is $1.1

Published
2016
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6. Target and Beam-Target Spin Asymmetries in Exclusive Pion Electroproduction for $Q^2>1$ GeV$^2$. I. $e p \rightarrow e \pi^+ n$

Author

Bosted, P. E., Amaryan, M. J., Pereira, S. Anefalos, Avakian, H., Badui, R. A., Ball, J., Baltzell, N. A., Battaglieri, M., Batourine, V., Bedlinskiy, I., Biselli, A. S., Briscoe, W. J., Bültmann, S., Burkert, V. D., Carman, D. S., Celentano, A., Chandavar, S., Charles, G., Clark, L., Colaneri, L., Cole, P. L., Contalbrigo, M., Crede, V., D'Angelo, A., De Vita, R., Deur, A., De Sanctis, E., Djalali, C., Dupre, R., Egiyan, H., Alaoui, A. El, Fassi, L. El, Elouadrhiri, L., Eugenio, P., Fanchini, E., Fedotov, G., Filippi, A., Fleming, J. A., Forest, T., Fradi, A., Gevorgyan, N., Gilfoyle, G. P., Girod, F. X., Gleason, C., Gohn, W., Golovatch, E., Gothe, R. W., Griffioen, K. A., Guidal, M., Hakobyan, H., Hattawy, M., Hicks, K., Holtrop, M., Hughes, S. M., Ilieva, Y., Ireland, D. G., Ishkhanov, B. S., Isupov, E. L., Jiang, H., Jo, H. S., Joo, K., Joosten, S., Khachatryan, G., Khandaker, M., Kim, A., Kim, W., Klein, F. J., Koirala, S., Kubarovsky, V., Kuhn, S. E., Lanza, L., Net, L. A., Lenisa, P., Livingston, K., MacGregor, I. J. D., McCracken, M. E., McKinnon, B., Meyer, C. A., Mirazita, M., Mokeev, V. I., Montgomery, R. A., Munevar, E., Camacho, C. Munoz, Murdoch, G., Nadel-Turonski, P., Niccolai, S., Osipenko, M., Ostrovidov, A. I., Park, K., Pasyuk, E., Peng, P., Phelps, W., Pisano, S., Pogorelko, O., Price, J. W., Prok, Y., Protopopescu, D., Raue, B. A., Ripani, M., Rosner, G., Rossi, P., Schumacher, R. A., Skorodumina, Iu., Smith, G. D., Sokhan, D., Sparveris, N., Stankovic, I., Strakovsky, I. I., Strauch, S., Taiuti, M., Torayev, B., Ungaro, M., Voskanyan, H., Voutier, E., Wei, X., Weinstein, L. B., Zhang, J., and Zonta, I.

Subjects
Nuclear Experiment
Abstract

Beam-target double-spin asymmetries and target single-spin asymmetries were measured for the exclusive $\pi^+$ electroproduction reaction $\gamma^* p \to n \pi^+$. The results were obtained from scattering of 6 GeV longitudinally polarized electrons off longitudinally polarized protons using the CEBAF Large Acceptance Spectrometer at Jefferson Lab. The kinematic range covered is $1.1

Published
2016
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7. Measurement of Target and Double-spin Asymmetries for the $\vec e\vec p\to e\pi^+ (n)$ Reaction in the Nucleon Resonance Region at Low $Q^2$

Author

Zheng, X., Adhikari, K. P., Bosted, P., Deur, A., Drozdov, V., Fassi, L. El, Kang, Hyekoo, Kovacs, K., Kuhn, S., Long, E., Phillips, S. K., Ripani, M., Slifer, K., Smith, L. C., Adikaram, D., Akbar, Z., Amaryan, M. J., Pereira, S. Anefalos, Asryan, G., Avakian, H., Badui, R. A., Ball, J., Baltzell, N. A., Battaglieri, M., Batourine, V., Bedlinskiy, I., Biselli, A. S., Briscoe, W. J., Bültmann, S., Burkert, V. D., Carman, D. S., Celentano, A., Chandavar, S., Charles, G., Chen, J. -P., Chetry, T., Choi, Seonho, Ciullo, G., Clark, L., Colaneri, L., Cole, P. L., Compton, N., Contalbrigo, M., Crede, V., D'Angelo, A., Dashyan, N., De Vita, R., De Sanctis, E., Djalali, C., Dodge, G. E., Dupre, R., Egiyan, H., Alaoui, A. El, Elouadrhiri, L., Eugenio, P., Fanchini, E., Fedotov, G., Fersch, R., Filippi, A., Fleming, J. A., Gevorgyan, N., Ghandilyan, Y., Gilfoyle, G. P., Giovanetti, K. L., Girod, F. X., Gleason, C., Golovach, E., Gothe, R. W., Griffioen, K. A., Guidal, M., Guler, N., Guo, L., Hanretty, C., Harrison, N., Hattawy, M., Hicks, K., Holtrop, M., Hughes, S. M., Ilieva, Y., Ireland, D. G., Ishkhanov, B. S., Isupov, E. L., Jenkins, D., Jiang, H., Jo, H. S., Joosten, S., Keller, D., Khachatryan, G., Khandaker, M., Kim, A., Kim, W., Klein, F. J., Kubarovsky, V., Lanza, L., Lenisa, P., Livingston, K., MacGregor, I . J . D., Markov, N., McKinnon, B., Mirazita, M., Mokeev, V., Movsisyan, A., Munevar, E., Camacho, C. Munoz, Murdoch, G., Nadel-Turonski, P., Net, L. A., Ni, A., Niccolai, S., Niculescu, G., Niculescu, I., Osipenko, M., Ostrovidov, A. I., Paolone, M., Paremuzyan, R., Park, K., Pasyuk, E., Peng, P., Pisano, S., Pogorelko, O., Price, J. W., Puckett, A. J. R., Raue, B. A., Rizzo, A., Rosner, G., Rossi, P., Roy, P., Sabatié, F., Salgado, C., Schumacher, R. A., Sharabian, Y. G., Skorodumina, Iu., Smith, G. D., Sokhan, D., Sparveris, N., Stankovic, I., Strakovsky, I. I., Strauch, S., Taiuti, M., Tian, Ye, Ungaro, M., Voskanyan, H., Voutier, E., Walford, N. K., Watts, D. P., Wei, X., Weinstein, L. B., Wood, M. H., Zachariou, N., and Zhang, J.

Subjects
Nuclear Experiment
Abstract

We report measurements of target- and double-spin asymmetries for the exclusive channel $\vec e\vec p\to e\pi^+ (n)$ in the nucleon resonance region at Jefferson Lab using the CEBAF Large Acceptance Spectrometer (CLAS). These asymmetries were extracted from data obtained using a longitudinally polarized NH$_3$ target and a longitudinally polarized electron beam with energies 1.1, 1.3, 2.0, 2.3 and 3.0 GeV. The new results are consistent with previous CLAS publications but are extended to a low $Q^2$ range from $0.0065$ to $0.35$ (GeV$/c$)$^2$. The $Q^2$ access was made possible by a custom-built Cherenkov detector that allowed the detection of electrons for scattering angles as low as $6^\circ$. These results are compared with the unitary isobar models JANR and MAID, the partial-wave analysis prediction from SAID and the dynamic model DMT. In many kinematic regions our results, in particular results on the target asymmetry, help to constrain the polarization-dependent components of these models., Comment: 20 pages, 15 figures, to appear in Phys. Rev. C

Published
2016
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8. Mechanical dyssynchrony as a selection criterion for cardiac resynchronization therapy: Design of the AMEND-CRT trial.

Author

Puvrez, A, Duchenne, J, Donal, E, Gorcsan, J, Patel, HC, Marwick, TH, Smiseth, OA, Søgaard, P, Stankovic, I, Diogo, PG, Vörös, G, Voigt, J-U, Puvrez, A, Duchenne, J, Donal, E, Gorcsan, J, Patel, HC, Marwick, TH, Smiseth, OA, Søgaard, P, Stankovic, I, Diogo, PG, Vörös, G, and Voigt, J-U

Abstract

AIMS: One third of patients do not improve after cardiac resynchronization therapy (CRT). Septal flash (SF) and apical rocking (ApRock) are deformation patterns observed on echocardiography in most patients eligible for CRT. These markers of mechanical dyssynchrony have been associated to improved outcome after CRT in observational studies and may be useful to better select patients. The aim of this trial is to investigate whether the current guideline criteria for selecting patients for CRT should be modified and include SF and ApRock to improve therapy success rate, reduce excessive costs and prevent exposure to device-related complications in patients who would not benefit from CRT. METHODS: The AMEND-CRT trial is a multicentre, randomized, parallel-group, double-blind, sham-controlled trial with a non-inferiority design. The trial will include 578 patients scheduled for CRT according to the 2021 ESC guidelines who satisfy all inclusion criteria. The randomization is performed 1:1 to an active control arm ('guideline arm') or an experimental arm ('echo arm'). All participants receive a device, but in the echo arm, CRT is activated only when SF or ApRock or both are present. The outcome of both arms will be compared after 1 year. The primary outcome measures are the average change in left ventricular end-systolic volume and patient outcome assessed using a modified Packer Clinical Composite Score. CONCLUSIONS: The findings of this trial will redefine the role of echocardiography in CRT and potentially determine which patients with heart failure and a prolonged QRS duration should receive CRT, especially in patients who currently have a class IIa or class IIb recommendation.

Published
2024

9. Characteristics of COPD Phenotypes in Serbia

Author

Lazic Z, Stankovic I, Milenkovic B, Zvezdin B, Hromis S, Jankovic S, and Cupurdija V

Subjects
chronic obstructive pulmonary disease, patient registry, phenotypes, Diseases of the respiratory system, RC705-779
Abstract

Zorica Lazic,1 Ivana Stankovic,2 Branislava Milenkovic,3 Biljana Zvezdin,4 Sanja Hromis,4 Slobodan Jankovic,5 Vojislav Cupurdija1 1Faculty of Medical Sciences, University of Kragujevac, and Clinic for Pulmonology, Clinical Centre, Kragujevac, Serbia; 2Faculty of Medicine, University of Niš, and Clinic for Lung Diseases, Clinical Centre, Niš, Serbia; 3Faculty of Medicine, University of Belgrade, and Clinic for Pulmonology, Clinical Centre of Serbia, Belgrade, Serbia; 4Faculty of Medicine, University of Novi Sad, and the Institute for Pulmonary Diseases of Vojvodina, Novi Sad, Serbia; 5Faculty of Medical Sciences, University of Kragujevac, and Clinical Pharmacology Department, Clinical Centre, Kragujevac, SerbiaCorrespondence: Slobodan JankovicFaculty of Medical Sciences, University of Kragujevac, Svetozara Markovića Street, 69, Kragujevac, 34000, SerbiaEmail slobnera@gmail.comBackground: Establishing a regional/national/international registry of patients suffering from chronic obstructive pulmonary disease (COPD) is essential for both research and healthcare, because it enables collection of comprehensive real-life data from a large number of individuals.Objective: The aim of this study was to describe characteristics of COPD patients from the Serbian patient registry, and to investigate actual differences of those characteristics among the COPD phenotypes.Methods: The Serbian registry of patients with COPD was established in 2018 at University of Kragujevac, Faculty of Medical Sciences, based on an online platform. Entry in the Registry was allowed for patients who were diagnosed with COPD according to the following criteria: symptoms of dyspnea, chronic cough or sputum production, history of risk factors for COPD and any degree of persistent airflow limitation diagnosed at spirometry.Results: In the Serbian COPD registry B and D GOLD group were dominant, while among the COPD phenotypes, the most prevalent were non-exacerbators (49.4%) and then frequent exacerbators without chronic bronchitis (29.6%). The frequent exacerbator with chronic bronchitis phenotype was associated with low levels of bronchopulmonary function and absolute predominance of GOLD D group. Anxiety, depression, insomnia, hypertension and chronic heart failure were the most prevalent in the frequent exacerbator with chronic bronchitis phenotype; patients with this phenotype were also treated more frequently than other patients with a triple combination of the most effective inhaled anti-obstructive drugs: long-acting muscarinic antagonists, long-acting beta 2 agonists and corticosteroids.Conclusion: In conclusion, the data from the Serbian registry are in line with those from other national registries, showing that frequent exacerbators with chronic bronchitis have worse bronchopulmonary function, more severe signs and symptoms, and more comorbidities (especially anxiety and depression) than other phenotypes. Other studies also confirmed worse quality of life and worse prognosis of the AE-CB phenotype, stressing importance of both preventive and appropriate therapeutic measures against chronic bronchitis.Keywords: chronic obstructive pulmonary disease, patient registry, phenotypes

Published
2021

10. Analysis Tools for Next-Generation Hadron Spectroscopy Experiments

Author

Battaglieri, M., Briscoe, B. J., Celentano, A., Chung, S. -U., D'Angelo, A., De Vita, R., Döring, M., Dudek, J., Eidelman, S., Fegan, S., Ferretti, J., Filippi, A., Fox, G., Galata, G., Garcia-Tecocoatzi, H., Glazier, D. I., Grube, B., Hanhart, C., Hoferichter, M., Hughes, S. M., Ireland, D. G., Ketzer, B., Klein, F. J., Kubis, B., Liu, B., Masjuan, P., Mathieu, V., McKinnon, B., Mitchell, R., Nerling, F., Paul, S., Pelaez, J. R., Rademacker, J., Rizzo, A., Salgado, C., Santopinto, E., Sarantsev, A. V., Sato, T., Schlüter, T., da Silva, M. L. L., Stankovic, I., Strakovsky, I., Szczepaniak, A., Vassallo, A., Walford, N. K., Watts, D. P., and Zana, L.

Subjects
High Energy Physics - Phenomenology
Abstract

The series of workshops on New Partial-Wave Analysis Tools for Next-Generation Hadron Spectroscopy Experiments was initiated with the ATHOS 2012 meeting, which took place in Camogli, Italy, June 20-22, 2012. It was followed by ATHOS 2013 in Kloster Seeon near Munich, Germany, May 21-24, 2013. The third, ATHOS3, meeting is planned for April 13-17, 2015 at The George Washington University Virginia Science and Technology Campus, USA. The workshops focus on the development of amplitude analysis tools for meson and baryon spectroscopy, and complement other programs in hadron spectroscopy organized in the recent past including the INT-JLab Workshop on Hadron Spectroscopy in Seattle in 2009, the International Workshop on Amplitude Analysis in Hadron Spectroscopy at the ECT*-Trento in 2011, the School on Amplitude Analysis in Modern Physics in Bad Honnef in 2011, the Jefferson Lab Advanced Study Institute Summer School in 2012, and the School on Concepts of Modern Amplitude Analysis Techniques in Flecken-Zechlin near Berlin in September 2013. The aim of this document is to summarize the discussions that took place at the ATHOS 2012 and ATHOS 2013 meetings. We do not attempt a comprehensive review of the field of amplitude analysis, but offer a collection of thoughts that we hope may lay the ground for such a document., Comment: 28 pages, 11 figures, proceedings of the ATHOS 2012 and ATHOS 2013 meetings

Published
2014
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11. EACVI survey on radiation exposure in interventional echocardiography.

Author

Galli, E, Soliman-Aboumarie, H, Gargani, L, Szymański, P, Gimelli, A, Petersen, S E, Sade, L E, Stankovic, I, Donal, E, Cosyns, B, Agricola, E, Dweck, M R, Marsan, N Ajmone, Delgado, V, and Muraru, D

Subjects
HEALTH literacy, RISK assessment, RADIATION protection, CARDIOVASCULAR diseases, PERSONAL protective equipment, ACADEMIC medical centers, CERTIFICATION, TERTIARY care, SURVEYS, WORLD health, OCCUPATIONAL exposure, NATIONAL competency-based educational tests, RADIATION doses, RADIATION-protective agents, ECHOCARDIOGRAPHY, TIME
Abstract

Aims The European Association of Cardiovascular Imaging (EACVI) Scientific Initiatives Committee performed a global survey on radiation exposure in interventional echocardiography. The survey aimed to collect data on local practices for radioprotection in interventional echocardiography and to assess the awareness of echocardiography operators about radiation-related risks. Methods and results A total of 258 interventional echocardiographers from 52 different countries (48% European) responded to the survey. One hundred twenty-two (47%) participants were women. Two-thirds (76%) of interventional echocardiographers worked in tertiary care/university hospitals. Interventional echocardiography was the main clinical activity for 34% of the survey participants. The median time spent in the cath-lab for the echocardiographic monitoring of structural heart procedures was 10 (5–20) hours/month. Despite this, only 28% of interventional echocardiographers received periodic training and certification in radioprotection and 72% of them did not know their annual radiation dose. The main adopted personal protection devices were lead aprons and thyroid collars (95% and 92% of use, respectively). Dedicated architectural protective shielding was not available for 33% of interventional echocardiographers. Nearly two-thirds of responders thought that the radiation exposure of interventional echocardiographers was higher than that of interventional cardiologists and 72% claimed for an improvement in the radioprotection measures. Conclusion Radioprotection measures for interventional echocardiographers are widely variable across centres. Radioprotection devices are often underused by interventional echocardiographers, portending an increased radiation-related risk. International scientific societies working in the field should collaborate to endorse radioprotection training, promote reliable radiation dose assessment, and support the adoption of radioprotection shielding dedicated to interventional echocardiographers. [ABSTRACT FROM AUTHOR]

Published
2024
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14. The CLAS12 Forward Tagger

Author

Acker, A., Attié, D., Aune, S., Ball, J., Baron, P., Bashkanov, M., Battaglieri, M., Behary, R., Benmokhtar, F., Bersani, A., Bertrand, Q., Besin, D., Bey, T., Black, P., Bonneau, P., Bossù, F., Boudouin, R., Boyer, M., Campero Rojas, P., Casale, A., Celentano, A., Cereseto, R., Ciarma, A., Cipro, F., Charles, G., Christiaens, G., Contrepois, P., Cook, M., D’Angelo, A., De Vita, R., Defurne, M., Delagnes, E., Fanchini, E., Fegan, S., Fleming, J., Filippi, A., Garçon, M., Georges, F., Giovanetti, K.L., Glazier, D.I., Granelli, R., Grouas, N., Hicks, K., Hoebel, A., Hughes, S.M., Lahonde, C., Lanza, L., Leffel, M., Lerch, T., Lemon, T., Livingston, K., Manco, A., Mandjavidze, I., Mann, H.S., McKinnon, B., Meunier, O., Miller, R., Miní, G., Mouden, Y., Musico, P., Osipenko, M., Ottonello, G., Parodi, F., Pasyuk, E., Pollovio, P., Pratolongo, F., Procureur, S., Puppo, R., Rossi, C., Riallot, M., Ripani, M., Rizzo, A., Sabatié, F., Salgado, C., Smith, G.D., Sokhan, D., Stankovic, I., Taiuti, M., Trovato, A., Vandenbroucke, M., Vigo, V., Virique, E., Watts, D., Wiggins, C., Zachariou, N., and Zana, L.

Published
2020
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17. Diagnosis and management of chronic obstructive pulmonary disease in Serbia: an expert group position statement

Author

Vukoja M, Kopitovic I, Lazic Z, Milenkovic B, Stankovic I, Zvezdin B, Dudvarski Ilic A, Cekerevac I, Vukcevic M, Zugic V, and Hromis S

Subjects
COPD, treatment, guidelines, Diseases of the respiratory system, RC705-779
Abstract

Marija Vukoja,1,2 Ivan Kopitovic,1,2 Zorica Lazic,3,4 Branislava Milenkovic,5,6 Ivana Stankovic,7,8 Biljana Zvezdin,1,2 Aleksandra Dudvarski Ilic,5,6 Ivan Cekerevac,3,4 Miodrag Vukcevic,6,9 Vladimir Zugic,5,6 Sanja Hromis1,21The Institute for Pulmonary Diseases of Vojvodina, Sremska Kamenica, Serbia; 2Faculty of Medicine, University of Novi Sad, Novi Sad, Serbia; 3Clinic for Pulmonology, Clinical Centre Kragujevac, Kragujevac, Serbia; 4Faculty of Medicine, University of Kragujevac, Kragujevac, Serbia; 5Clinic for Pulmonology, Clinical Centre of Serbia, Belgrade, Serbia; 6Faculty of Medicine, University of Belgrade, Belgrade, Serbia; 7Clinic for Lung Diseases, Clinical Centre of Nis, Nis, Serbia; 8Faculty of Medicine, University of Nis, Nis, Serbia; 9Clinical Hospital Centre Zemun, Belgrade, SerbiaCorrespondence: Marija VukojaCentre for Pathophysiology of Breathing and Sleep Medicine, The Institute for Pulmonary Diseases of Vojvodina, Put dr Goldmana 4 Street Sremska Kamenica 21204, SerbiaTel +381 21 480 5205Email marija.vukoja@mf.uns.ac.rsAbstract: In recent years, several national chronic obstructive pulmonary disease (COPD) guidelines have been issued. In Serbia, the burden of COPD is high and most of the patients are diagnosed at late stages. Global Initiative for Chronic Obstructive Lung Disease (GOLD) strategy is poorly implemented in real-life practice, as many patients are still prescribed inhaled corticosteroids (ICS)-containing regimens and slow-release theophylline. In this document, we propose an algorithm for treating COPD patients in Serbia based on national experts’ opinion, taking into account global recommendations and recent findings from clinical trials that are tailored according to local needs. We identified four major components of COPD treatment based on country specifics: active case finding and early diagnosis in high-risk population, therapeutic algorithm for initiation and escalation of therapy that is simple and easy to use in real-life practice, de-escalation of ICS in low-risk non-exacerbators, and individual choice of inhaler device based on patients’ ability and preferences. With this approach we aim to facilitate implementation of the recommendation, initiate the treatment in early stages, improve cost-effectiveness, reduce possible side effects, and ensure efficient treatment.Keywords: COPD, treatment, guidelines

Published
2019

19. Right ventricular longitudinal strain in the clinical routine: a state-of-the-art review

Author

Muraru, D, Haugaa, K, Donal, E, Stankovic, I, Voigt, J, Petersen, S, Popescu, B, Marwick, T, Muraru D., Haugaa K., Donal E., Stankovic I., Voigt J. U., Petersen S. E., Popescu B. A., Marwick T., Muraru, D, Haugaa, K, Donal, E, Stankovic, I, Voigt, J, Petersen, S, Popescu, B, Marwick, T, Muraru D., Haugaa K., Donal E., Stankovic I., Voigt J. U., Petersen S. E., Popescu B. A., and Marwick T.

Abstract

Myocardial deformation imaging is a very attractive clinical tool for the assessment of right ventricular (RV) systolic performance, providing incremental diagnostic and prognostic information over the traditional indices of RV function. Among various imaging modalities, echocardiography is currently the method of choice for clinical assessment of RV longitudinal strain (RVLS). The methodology of 2D speckle-tracking echocardiography to obtain RVLS has been recently standardized and demonstrated to be feasible, accurate, and robust for clinical use. Inter-technique and inter-vendor comparability and reliability of RVLS are improving. RVLS is advantageous because it is more sensitive to subtle changes in myocardial function than conventional parameters used to assess RV function (i.e. tricuspid annular plane systolic excursion, tissue Doppler systolic velocity, fractional area change, or RV ejection fraction) representing a sensitive tool for the long-term follow-up of patients. Proper interpretation of measurements requires a deep understanding of RV mechanics and pathologic tissue characteristics in different cardiovascular conditions, as well as the influence of loading conditions, image properties, and tracking algorithms on RVLS measurements.

Published
2022

20. How to assess severe tricuspid regurgitation by echocardiography?

Author

Sade, L, Muraru, D, Marsan, N, Agricola, E, Stankovic, I, Donal, E, Sade L. E., Muraru D., Marsan N. A., Agricola E., Stankovic I., Donal E., Sade, L, Muraru, D, Marsan, N, Agricola, E, Stankovic, I, Donal, E, Sade L. E., Muraru D., Marsan N. A., Agricola E., Stankovic I., and Donal E.

Published
2022

21. EACVI SIMULATOR-online study: evaluation of transoesophageal echocardiography knowledge and skills of young cardiologists

Author

Pezel, T., Coisne, A., Michalski, B., Soliman, H., Ajmone, N., Nijveldt, R., Stankovic, I., Donal, E., Maaten, J. Van Der, Papadopoulos, Constantinos, Edvardsen, T., Muraru, D., Petersen, Steffen E., Cosyns, B., Bäck, M., Bertrand, P.B., Haugaa, K.H., Keenen, Niall, Pezel, T., Coisne, A., Michalski, B., Soliman, H., Ajmone, N., Nijveldt, R., Stankovic, I., Donal, E., Maaten, J. Van Der, Papadopoulos, Constantinos, Edvardsen, T., Muraru, D., Petersen, Steffen E., Cosyns, B., Bäck, M., Bertrand, P.B., Haugaa, K.H., and Keenen, Niall

Abstract

Item does not contain fulltext

Published
2023

22. EACVI SIMULATOR-online study: evaluation of transoesophageal echocardiography knowledge and skills of young cardiologists

Author

Pezel, T, Coisne, A, Michalski, B, Soliman, H, Ajmone, N, Nijveldt, R, Stankovic, I, Donal, E, van der Maaten, J, Papadopoulos, C, Edvardsen, T, Muraru, D, Petersen, S, Cosyns, B, Pezel, Théo, Coisne, Augustin, Michalski, Błażej, Soliman, Hatem, Ajmone, Nina, Nijveldt, Robin, Stankovic, Ivan, Donal, Erwan, van der Maaten, Joost, Papadopoulos, Constantinos, Edvardsen, Thor, Muraru, Denisa, Petersen, Steffen E, Cosyns, Bernard, Pezel, T, Coisne, A, Michalski, B, Soliman, H, Ajmone, N, Nijveldt, R, Stankovic, I, Donal, E, van der Maaten, J, Papadopoulos, C, Edvardsen, T, Muraru, D, Petersen, S, Cosyns, B, Pezel, Théo, Coisne, Augustin, Michalski, Błażej, Soliman, Hatem, Ajmone, Nina, Nijveldt, Robin, Stankovic, Ivan, Donal, Erwan, van der Maaten, Joost, Papadopoulos, Constantinos, Edvardsen, Thor, Muraru, Denisa, Petersen, Steffen E, and Cosyns, Bernard

Abstract

AIMS: To assess the level of transesophageal echocardiography (TOE) knowledge and skills of young cardiologists. METHODS AND RESULTS: A European Association of Cardiovascular Imaging (EACVI) online study using the first fully virtual simulation-based software was conducted in two periods (9-12 December 2021 and 10-13 April 2022). All young cardiologists eligible to participate (<40 years) across the world were invited to participate. After a short survey, each participant completed two tests: a theoretical test to assess TOE knowledge and a practical test using an online TOE simulator to investigate TOE skills. Among 716 young cardiologists from 81 countries, the mean theoretical test score was 56.8 ± 20.9 points, and the mean practical test score was 47.4 ± 7.2 points (/100 points max each), including 18.4 ± 8.7 points for the acquisition test score and 29.0 ± 6.7 points for the anatomy test score (/50 points max each). Acquisition test scores were higher for four-chamber (2.3 ± 1.5 points), two-chamber (2.2 ± 1.4 points) and three-chamber views (2.3 ± 1.4 points) than for other views (all P < 0.001). Prior participation to a TOE simulation-based training session, a higher number of TOE exams performed per week, and EACVI certification for TOE were independently associated with a higher global score (all P < 0.001). CONCLUSION: Online evaluation of young cardiologists around the world showed a relatively low level of TOE skills and knowledge. Prior participation to a TOE simulation-based training session, a higher number of TOE exams performed per week, and the EACVI certification for TOE were independently associated with a higher global score.

Published
2023

23. Infographic. Oxford consensus on primary cam morphology and femoroacetabular impingement syndrome-natural history of primary cam morphology to inform clinical practice and research priorities on conditions affecting the young person's hip

Author

Dijkstra, HP, Mc Auliffe, S, Ardern, CL, Kemp, JL, Mosler, AB, Price, A, Blazey, P, Richards, D, Farooq, A, Serner, A, McNally, E, Mascarenhas, V, Willy, RW, Stankovic, I, Oke, JL, Khan, KM, Glyn-Jones, S, Clarke, M, Greenhalgh, T, and Collaborative, Young Athlete’s Hip Research (YAHiR)

Subjects
Consensus, Hip, Research, Osteoarthritis, Physical Therapy, Sports Therapy and Rehabilitation, Orthopedics and Sports Medicine, General Medicine, Groin
Published
2023

24. Changes in respiratory function impairment following the treatment of severe pulmonary tuberculosis – limitations for the underlying COPD detection

Author

Radovic M, Ristic L, Ciric Z, Dinic-Radovic V, Stankovic I, Pejcic T, Rancic M, and Bogdanovic D

Subjects
tuberculosis, pulmonary, respiratory function tests, lung diseases, obstructive., Diseases of the respiratory system, RC705-779
Abstract

Milan Radovic,1,2 Lidija Ristic,1,2 Zorica Ciric,1,2 Violeta Dinic-Radovic,3 Ivana Stankovic,1,2 Tatjana Pejcic,1,2 Milan Rancic,1,2 Dragan Bogdanovic4 1Department of Internal Medicine, Faculty of Medicine, University of Nis, 2Clinic for Lung Diseases, 3Clinic for Gastroenterology and Hepatology, Clinical Centre of Nis, 4Public Health Institute Nis, Nis, Republic of Serbia Background: During the treatment phase of active pulmonary tuberculosis (PTB), respiratory function impairment is usually restrictive. This may become obstructive, as a PTB-associated airflow obstruction (AFO) or as a later manifestation of underlying COPD.Purpose: The aim of the study was to examine the potential causes and risks for AFO development in PTB by exploring the aspects of spirometry limitations and clinical implications for the underlying COPD detection, taking into account various confounding factors.Patients and methods: Prospective, nest case–control study on 40 new cases of PTB with initial restrictive respiratory function impairment, diagnosed and treated according to the directly observed treatment short course (DOTS) strategy.Results: From all observed patients, 37.5% of them developed AFO upon the completion of PTB treatment, with significantly increased average of forced vital capacity (%) (P

Published
2016

25. Level 1 of Entrustable Professional Activities in adult echocardiography: A position statement from the EACVI regarding the training and competence requirements for selecting and interpreting echocardiographic examinations

Author

Stankovic, I, Muraru, D, Fox, K, Di Salvo, G, Hasselberg, N, Breithardt, O, Hansen, T, Neskovic, A, Gargani, L, Cosyns, B, Edvardsen, T, Stankovic I., Muraru D., Fox K., Di Salvo G., Hasselberg N. E., Breithardt O. -A., Hansen T. B., Neskovic A. N., Gargani L., Cosyns B., Edvardsen T., Stankovic, I, Muraru, D, Fox, K, Di Salvo, G, Hasselberg, N, Breithardt, O, Hansen, T, Neskovic, A, Gargani, L, Cosyns, B, Edvardsen, T, Stankovic I., Muraru D., Fox K., Di Salvo G., Hasselberg N. E., Breithardt O. -A., Hansen T. B., Neskovic A. N., Gargani L., Cosyns B., and Edvardsen T.

Abstract

The goal of Level 1 training in echocardiography is to enable the trainee to select echocardiography appropriately for the evaluation of a specific clinical question, and then to interpret the report. It is not the goal of Level 1 training to teach how to perform the examination itself - that is the goal of higher levels of training. However, understanding the principles, indications, and findings of this crucial technique is valuable to many medical professionals including outside cardiology. This should be seen as part of a general understanding of cardiac imaging modalities. The purpose of this position statement is to define the scope and outline the general requirements for Level 1 training and competence in echocardiography. Moreover, the document aims to make a clear distinction between Level 1 competence in echocardiography and focus cardiac ultrasound (FoCUS).

Published
2021

30. The Movement Disorder Society Criteria for the Diagnosis of Multiple System Atrophy

Author

Wenning, G.K. Stankovic, I. Vignatelli, L. Fanciulli, A. Calandra-Buonaura, G. Seppi, K. Palma, J.-A. Meissner, W.G. Krismer, F. Berg, D. Cortelli, P. Freeman, R. Halliday, G. Höglinger, G. Lang, A. Ling, H. Litvan, I. Low, P. Miki, Y. Panicker, J. Pellecchia, M.T. Quinn, N. Sakakibara, R. Stamelou, M. Tolosa, E. Tsuji, S. Warner, T. Poewe, W. Kaufmann, H.

Subjects
nervous system, stomatognathic system, parasitic diseases, mental disorders, nervous system diseases
Abstract

Background: The second consensus criteria for the diagnosis of multiple system atrophy (MSA) are widely recognized as the reference standard for clinical research, but lack sensitivity to diagnose the disease at early stages. Objective: To develop novel Movement Disorder Society (MDS) criteria for MSA diagnosis using an evidence-based and consensus-based methodology. Methods: We identified shortcomings of the second consensus criteria for MSA diagnosis and conducted a systematic literature review to answer predefined questions on clinical presentation and diagnostic tools relevant for MSA diagnosis. The criteria were developed and later optimized using two Delphi rounds within the MSA Criteria Revision Task Force, a survey for MDS membership, and a virtual Consensus Conference. Results: The criteria for neuropathologically established MSA remain unchanged. For a clinical MSA diagnosis a new category of clinically established MSA is introduced, aiming for maximum specificity with acceptable sensitivity. A category of clinically probable MSA is defined to enhance sensitivity while maintaining specificity. A research category of possible prodromal MSA is designed to capture patients in the earliest stages when symptoms and signs are present, but do not meet the threshold for clinically established or clinically probable MSA. Brain magnetic resonance imaging markers suggestive of MSA are required for the diagnosis of clinically established MSA. The number of research biomarkers that support all clinical diagnostic categories will likely grow. Conclusions: This set of MDS MSA diagnostic criteria aims at improving the diagnostic accuracy, particularly in early disease stages. It requires validation in a prospective clinical and a clinicopathological study. © 2022 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society. © 2022 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.

Published
2022

34. Rethinking neurological attitudes towards vasovagal syncope: The European Federation of Autonomic Societies (EFAS) recommendations regarding tilt table testing

Author

van Dijk, J.G., Thijs, R., Brignole, M., Falup‐Pecurariu, C., Fanciulli, A., Freeman, R., Guaraldi, P., Jordan, J., Habek, M., Hilz, M.J., Pavy‐Le Traon, A., Stankovic, I., Struhal, W., Sutton, R., and Wenning, G.K.

Subjects
medicine.medical_specialty, MEDLINE, Autonomic Nervous System, Physical medicine and rehabilitation, Heart Rate, Tilt-Table Test, medicine, Syncope, Vasovagal, Humans, European Federation of Autonomic Societies (EFAS) Task Force on Tilt Table Testing, Vasovagal syncope, neurological, Neurology & Neurosurgery, business.industry, tilt table testing, 1103 Clinical Sciences, medicine.disease, EFAS, vasovagal syncope, Tilt (optics), Neurology, Attitude, Table (database), Neurology (clinical), 1109 Neurosciences, business
Published
2021

36. Laboratory‐Supported Multiple System Atrophy beyond Autonomic Function Testing and Imaging: A Systematic Review by the MoDiMSA Study Group

Author

Stankovic, I., Fanciulli, A., Kostic, V. S., Krismer, F., Meissner, W. G., Palma, J. A., Panicker, J. N., Seppi, K., Pellecchia, M. T., and Wenning, G. K.

Subjects
0301 basic medicine, medicine.medical_specialty, Movement disorders, multiple system atrophy, Reviews, 030105 genetics & heredity, REM sleep behavior disorder, diagnostic tests, 03 medical and health sciences, 0302 clinical medicine, Physical medicine and rehabilitation, Atrophy, Neuroimaging, stomatognathic system, mental disorders, medicine, Dementia, Pure autonomic failure, business.industry, Neuropsychology, medicine.disease, 3. Good health, nervous system diseases, Neurology, nervous system, Spinocerebellar ataxia, Neurology (clinical), medicine.symptom, business, 030217 neurology & neurosurgery
Abstract

Author(s): Stankovic, Iva; Fanciulli, Alessandra; Kostic, Vladimir S; Krismer, Florian; Meissner, Wassilios G; Palma, Jose Alberto; Panicker, Jalesh N; Seppi, Klaus; Wenning, Gregor K; MoDiMSA Study Group | Abstract: Background: Neuroimaging has been used to support a diagnosis of possible multiple system atrophy (MSA). Only blood pressure changes upon standing are included in the second consensus criteria but other autonomic function tests (AFT) are also useful to diagnose widespread and progressive autonomic failure typical of MSA. Additional diagnostic tools are of interest to improve accuracy of MSA diagnosis. Objectives: To assess the utility of diagnostic tools beyond brain imaging and AFT in enhancing a laboratory-supported diagnosis of MSA to support the upcoming revision of the consensus criteria. Methods: The International Parkinson and Movement Disorders Society MSA Study Group (MoDiMSA) performed a systematic review of original papers on biomarkers, sleep studies, genetic, neuroendocrine, neurophysiological, neuropsychological and other tests including olfactory testing and acute levodopa challenge test published before August 2019. Results: Evaluation of history of levodopa responsiveness and olfaction is useful in patients in whom MSA-parkinsonian subtype is suspected. Neuropsychological testing is useful to exclude dementia at time of diagnosis. Applicability of sphincter EMG is limited. When MSA-cerebellar subtype is suspected, a screening for the common causes of adult-onset progressive ataxia is useful, including spinocerebellar ataxias in selected patients. Diagnosing stridor and REM sleep behavior disorder is useful in both MSA subtypes. However, none of these tools are validated in large longitudinal cohorts of postmortem confirmed MSA cases. Conclusions: Despite limited evidence, additional laboratory work-up of patients with possible MSA beyond imaging and AFT should be considered to optimize the clinical diagnostic accuracy.

Published
2021

45. Apathy in early Parkinson’s disease: EP4223

Author

Stojkovic, T., Stankovic, I., Tomic, A., Jecmenica, M., Kresojevic, N., Mandic, G., Markovic, V., Stefanova, E., Svetel, M., Miskovic, N., Petrovic, I., and Kostic, V. S.

Published
2014

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