12 results on '"Soussana, M."'
Search Results
2. Social skills improvement in children with high-functioning autism: a pilot randomized controlled trial
- Author
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Baghdadli, A., Brisot, J., Henry, V., Michelon, C., Soussana, M., Rattaz, C., and Picot, M. C.
- Published
- 2013
- Full Text
- View/download PDF
3. Impact des troubles anxieux sur la qualité de vie des adolescents avec un trouble du spectre autistique sans déficience intellectuelle
- Author
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Broquere, M., primary, Soussana, M., additional, Michelon, C., additional, Rattaz, C., additional, Brisot, J., additional, and Baghdadli, A., additional
- Published
- 2016
- Full Text
- View/download PDF
4. Olive Consumption and Health
- Author
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Savalas, Constantinos A., Nicolau, Soussana M., Savalas, Constantinos A., and Nicolau, Soussana M.
- Subjects
- Unsaturated fatty acids in human nutrition, Antioxidants, Vegetable oils in human nutrition, Olive oil--Health aspects, Vegetable oils
- Abstract
Olive oil, which has been part of the human diet for more than 5,000 years, is almost unique among oils in that it can be consumed in the crude form without refining. This has the effect of conserving all its vitamins, essential fatty acids, and other nutrients. In addition to the fatty acid profile of olive oil, which is high in the monounsaturated oleic acid and appears to be beneficial in reducing several risk factors for coronary heart disease and certain cancers, extra virgin olive oil contains powerful antioxidants. In this book, the authors present topical research on the health benefits of olive consumption. Some of the topics discussed include dynamic rheology and sensory properties determined by inulin/extra virgin olive oil and virgin olive oil antioxidants; olive oil and postprandial lipemia.
- Published
- 2012
5. Troubles anxieux dans les troubles envahissants du développement sans retard mental : état des lieux chez les enfants et les adolescents au travers d’une revue de la littérature
- Author
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Soussana, M., primary, Sunyer, B., additional, Pry, R., additional, and Baghdadli, A., additional
- Published
- 2012
- Full Text
- View/download PDF
6. Double-blind, placebo-controlled immunotherapy with mixed grass-pollen allergoids
- Author
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Bousquet, J., primary, Hejjaoui, A., additional, Soussana, M., additional, and Michel, F-B., additional
- Published
- 1990
- Full Text
- View/download PDF
7. Olive oil phenolics and oxidative stress
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Colin, Veronica Leticia, Savalas, Constantinos A., and Nicolau, Soussana M.
- Subjects
Nutrición, Dietética ,CIENCIAS MÉDICAS Y DE LA SALUD ,Ciencias de la Salud ,OLIVE OIL ,OXIDATIVE STRESS ,PHENOLIC COMPOUNDS - Abstract
Olive oil, which has been part of the human diet for more than 5000 years, is almost unique among oils in that it can be consumed in the crude form without refining. This has the effect of conserving all its vitamins, essential fatty acids, and other nutrients. In addition to the fatty acid profile of olive oil, which is high in the monounsaturated oleic acid and appears to be beneficial in reducing several risk factors for coronary heart disease and certain cancers, extra virgin olive oil contains powerful antioxidants. In this connection, the incidence of degenerative pathologies, including those in which the excessive free radical formation has been suggested, is very low in the Mediterranean area, where the diet is rich in antioxidant compounds. Among such antioxidants, the contribution of olive oil phenolics is currently under active investigation, since they affords considerable protection against cancer (colon, breast, and skin), coronary heart disease, and ageing by inhibiting oxidative stress. This chapter focuses on antioxidant role and additional biological actions of olive oil phenolics. Fil: Colin, Veronica Leticia. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Tucumán. Planta Piloto de Procesos Industriales Microbiológicos; Argentina
- Published
- 2012
8. [Impact of anxiety disorders on quality of life of adolescents with autism spectrum disorder without intellectual disability].
- Author
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Broquere M, Soussana M, Michelon C, Rattaz C, Brisot J, and Baghdadli A
- Subjects
- Adolescent, Anxiety Disorders complications, Anxiety Disorders epidemiology, Asperger Syndrome complications, Asperger Syndrome psychology, Autism Spectrum Disorder complications, Autism Spectrum Disorder epidemiology, Child, Female, Humans, Intellectual Disability, Intelligence, Male, Parents, Prevalence, Prognosis, Risk Factors, Anxiety Disorders psychology, Autism Spectrum Disorder psychology, Quality of Life
- Abstract
Introduction: The prevalence of anxiety disorders has been recently estimated at 42 % in a population of adolescents with autism spectrum disorder without intellectual disability. This rate is more than two times higher than in adolescents without developmental disorders (around 20 %). Besides, according to recent studies, the quality of life of adolescents with ASD without mental retardation seems to be lower than adolescents with typical development. We guess that anxiety disorders may be responsible for a low quality of life in adolescents with ASD., Objectives: The aim of this study was to describe the relationship between quality of life and anxiety disorders. The first objective was to determine if anxiety disorders are a risk factor for having a low quality of life in adolescents with ASD. The second objective was to confirm this link with another comparison using a control group of adolescents with an anxiety disorder but without ASD. Our hypothesis was that anxiety disorder is a risk factor to decrease the quality of life of adolescents with ASD., Methods: This research was a transversal descriptive and comparative study. Sixty-six adolescents aged between 11 and 18years old were included: 46 with ASD without mental retardation and 20 controls (with anxiety disorders without ASD). Among the ASD group, 20 patients were identified as having an anxiety disorder according to international classifications of mental diseases, and 26 adolescents had no psychiatric comorbidity. Quality of Life (QoL) was reported in five domains with the KIDSCREEN-27, for each patient in the three different groups. Diagnosis of anxiety disorders was assessed using the Kiddie-SADS-PL. The level of anxiety was measured with a self-report questionnaire (RC-MAS). We compared the anxiety rates and the QoL levels between the two groups of adolescents with ASD, one with anxiety disorders, the other without anxiety disorder. Comparisons were also made with QoL data from the general population., Results: Quality of life in the two different groups of adolescents with ASD without mental retardation (with and without anxiety disorders) was significantly lower than in adolescents in the general population. Those rates were significantly lower in the group with ASD and anxiety disorders than in the group with ASD without anxiety disorders for the domain of "physical well-being" only. There was no significant difference between the groups regarding the four other domains of the Kidscreen-27. Moreover, there was no difference between adolescents with ASD and adolescents without ASD regarding the perceived level of anxiety., Conclusion: This study shows that anxiety disorders could be a risk factor for impairment of the "physical well-being" dimension of QoL in adolescents with ASD without intellectual disability. Results highlight the interest of a self-evaluation of anxiety level in a population of adolescents with ASD. Findings about self-report of QoL might be temper probably due to the insight difficulties that meet patients with ASD reported in literature review. Further research need to be done with larger samples of patients using self-evaluation coupled with hetero-evaluation such as parents' reports and clinicians' reports., (Copyright © 2016. Published by Elsevier Masson SAS.)
- Published
- 2016
- Full Text
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9. Connective tissue problems and attention deficit and hyperactivity.
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Baeza-Velasco C, Soussana M, and Baghdadli A
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- Child, Humans, Male, Attention Deficit Disorder with Hyperactivity complications, Connective Tissue Diseases complications, Genetic Diseases, Inborn complications
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- 2015
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10. [Implementation of a French cohort of children or adolescents with autism spectrum disorders: ELENA cohort].
- Author
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Baghdadli A, Loubersac J, Soussana M, Rattaz C, and Michelon C
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- Adolescent, Child, Child, Preschool, Cohort Studies, Family Health, Female, France, Humans, Longitudinal Studies, Male, Prospective Studies, Quality of Life, Research Design, Autism Spectrum Disorder complications, Autism Spectrum Disorder therapy
- Abstract
Background: Multidisciplinary cohort studies of children with autism spectrum disorders (ASD) followed from childhood to adulthood exist abroad but not in France. The objective of the ELENA French cohort is to study the developmental trajectories of children and adolescents with ASD and their risk or protective associated factors., Methods: This is an open, prospective and multicenter cohort study, including children and adolescents under 16 years of age with ASD recruited from services specialized in the assessment of developmental disorders. The patients will be monitored every 18 months for at least 36 months and during a maximum of 10 years. Clinical, social, environmental, and genetic data, as well as data relating to the parental quality of life will be collected. The primary endpoint will be the adaptive level in three domains of the Vineland II (communication, socialization and daily living skills). The secondary endpoints will be parental quality of life, comorbidities, interventions and severity of ASD., Expected Results and Perspectives: The inclusion of 1600 patients over a 10-year period is expected. This cohort should contribute to a better knowledge of the child developing an ASD, taking into account the physical, social and familial environment, the type of interventions and some genetic components. It should also lay the foundations for a national network of professionals working in the field of autism research by offering them a common tool for promoting translational studies., (Copyright © 2014 Elsevier Masson SAS. All rights reserved.)
- Published
- 2014
- Full Text
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11. [Anxiety in children and adolescents with pervasive developmental disorder without mental retardation: review of literature].
- Author
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Soussana M, Sunyer B, Pry R, and Baghdadli A
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- Adolescent, Age Factors, Anti-Anxiety Agents therapeutic use, Anxiety Disorders therapy, Child, Child Development Disorders, Pervasive therapy, Cognitive Behavioral Therapy, Comorbidity, Cross-Sectional Studies, Female, Humans, Intellectual Disability therapy, Intelligence, Interview, Psychological, Male, Personality Assessment, Anxiety Disorders diagnosis, Anxiety Disorders epidemiology, Child Development Disorders, Pervasive diagnosis, Child Development Disorders, Pervasive epidemiology, Intellectual Disability diagnosis, Intellectual Disability epidemiology
- Abstract
Objective: Anxiety is highly prevalent in Pervasive Developmental Disorder (PDD) without mental retardation but is too often misdiagnosed. The authors suggest a critical review of current data of the PDD without mental retardation in children and adolescents, in order to summarize research published in this field. After describing specific features, this article tackles the issue of prevalence of anxiety among this population, then deals with present-time assessment and treatments of comorbid anxiety., Methods: This review was based on a systematic search of the main online databases (Science Direct, PsychInfo, Medline and Pubmed) in order to compile surveys published on Asperger syndrome and high-functioning autism-related anxiety among children and adolescents. This study focuses on papers published between 1995 and 2010, using strict diagnostic criteria for anxiety and PDD, and a controlled group, with the exception of pharmacological studies because none are controlled. We found seven studies assessing the prevalence of anxiety among children and adolescents with PDD, four assessment tools and 12 treatments., Results: Anxiety disorders were shown in 42% of children and adolescents with PDD without mental retardation. This disorder is related to age and level of cognitive functioning and is likely to affect PDD without mental retardation as children and adolescents with anxiety disorder without PDD. This review highlights a major problem: assessment of anxiety in PDD without mental retardation. Actually, only two PDD adapted instruments have been found: the Autism Co-Morbidity Interview Present and Lifetime Version (ACI-PI) and the Stress Survey Schedule (SSS) for persons with autism. Such tools being methodologically limited, the diagnosis of anxiety disorder is all the more difficult to establish. Consequently, considering suitable treatment is not always proposed. Recent surveys show how profitable pharmacological treatment and behavioral intervention like Cognitive-Behavior Therapy (CBT) or psychosocial treatments are. However, important methodological limitations are evoked: there is no control study assessing the efficiency of a pharmacological treatment in Asperger syndrome and high-functioning autism. Besides, the research on how profitable cognitive and behavioral treatment is, gives heterogeneous results. Finally, social skills' training does not treat anxiety disorder directly, but skills abilities that are the most important disabilities in PDD without mental retardation. Therefore, authors advocate adapting treatment in order to treat anxiety disorder., Conclusion: The research revealed an important need to create new assessment instruments suitable to PDD without mental retardation in order to facilitate the co-morbidity diagnosis. This survey also underlines the necessity to develop controlled research testing the efficiency of such treatments as pharmacological ones, cognitive and behavioral therapies as well as social skills training., (Copyright © 2011 L’Encéphale, Paris. Published by Elsevier Masson SAS. All rights reserved.)
- Published
- 2012
- Full Text
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12. Double-blind, placebo-controlled immunotherapy with a high-molecular-weight, formalinized allergoid in grass pollen allergy.
- Author
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Bousquet J, Frank E, Soussana M, Hejjaoui A, Maasch HJ, and Michel FB
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- Adolescent, Adult, Allergoids, Clinical Trials as Topic, Double-Blind Method, Humans, Nasal Provocation Tests, Poaceae, Pollen, Random Allocation, Desensitization, Immunologic, Plant Extracts therapeutic use, Rhinitis, Allergic, Seasonal therapy
- Abstract
Specific immunotherapy is effective in grass pollen allergy with standardized extracts and formalinized allergoids; but systemic reactions are not uncommon. A high-molecular-weight (greater than 85,000 daltons), formalinized allergoid was investigated in a double-blind, placebo-controlled study to assess its safety and efficacy. Twenty patients received a placebo and 39 the allergoid using a rather aggressive protocol. Five patients developed a mild and transient systemic reaction with high doses of allergoid and one had a more severe reaction requiring treatment. Nasal challenges performed with orchard grass pollen grains showed that the threshold number of grains eliciting nasal symptoms was significantly (p less than 0.01) greater in the treated group. This group had significantly (p less than 0.01) less nasal symptoms during the season and specific IgG levels were significantly (p less than 0.01) elevated. There was a significant (p less than 0.01) correlation between nasal challenges and nasal symptoms during the season but no correlation between IgG and symptoms. There was no dose-dependent effect of allergoids.
- Published
- 1987
- Full Text
- View/download PDF
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