In 2010, 7.6 million children under five died globally – largely due to preventable diseases including pneumonia (14%), diarrhea (10%), and malaria (7%) [1]. Ninety–nine percent of these deaths occurred in low–resource settings and nearly half (47%) in Sub–Saharan Africa in communities where people have limited or no access to life saving interventions and medical supplies. Integrated Community Case Management (iCCM) is a strategy designed to bring care and treatment for childhood pneumonia, diarrhea, and malaria closer home by training community health workers (CHW) in the identification and treatment of common childhood illnesses [2,3]. iCCM involves training CHWs on essential health packages and ensuring that they have the medicines needed to manage and treat illnesses among children under five years of age. Continuous access to these medicines by CHWs requires a well–functioning supply chain across all levels of the health care system. However, the supply chain systems of many resource–constrained countries function poorly and face a myriad of challenges [4], including but not limited to shortage of human resources, weak inventory management, low supply chain skills among health workers, and a lack of data visibility and utilization for sound decision making. In 2008, the Government of Malawi (GoM) initiated iCCM as a strategy to reduce child mortality. The program entailed training an existing cadre of CHWs, known as Health Surveillance Assistants (HSAs) to treat children in the community. HSAs are posted nationwide to serve communities at a ratio of 1:1000 population. By September 2011, 3296 HSAs had been trained in integrated management of childhood illness (IMCI) [5]. With the implementation of the iCCM strategy in Malawi, mortality among children under five years decreased from 225 deaths per 1000 live births in 1990 to 71 per 1000 live births in 2012 [6], and the country is considered on track to achieve Millennium Development Goal (MDG) 4, to reduce child–mortality by two–thirds, by 2015. Despite the gains made towards MDG 4, the health care infrastructure in Malawi still faces challenges, among them weak supply chain systems. This affects continuous health product availability at the community level, consequently undermining the full effectiveness of the iCCM strategy. In order to identify the constraints associated with maintaining regular product availability, Supply Chains for Community Case Management (SC4CCM) in collaboration with the Ministry of Health (MOH), conducted a formative assessment across 10 districts in Malawi (Nkhatabay, Nkhotakota, Mulanje, Kasungu, Nsanje, Machinga, Mzimba North, Zomba, Nchitsi, and Salima) in 2010 [7]. The assessment identified poor availability and limited use of logistics data (ie, low data visibility) across all levels of the health system, low motivation among HSAs and transport challenges such as difficult terrain and long travel time for HSAs to collect products as key barriers to continuous product availability. This assessment identified additional opportunities of using mobile phones to promote data visibility as 89% of the HSAs surveyed had mobile phones, 80% of HSAs and health facility (HF) staff had continuous network coverage at their place of work and all districts surveyed had computers and access to the Internet. The survey also found high levels (80%) of bicycle ownership among the HSAs [7]. To address the identified constraints related to data visibility, motivation and transport, SC4CCM designed and piloted cStock, a mHealth tool for community–level reporting of stock on hand data and resupply of 19 health products managed by HSAs. cStock was nested within two broader interventions, namely, Enhanced Management (EM) and Efficient Product Transport (EPT), to address challenges in motivation of HSAs and transport to the health facilities, respectively. The primary objective of this paper is to assess the feasibility, acceptability, and effectiveness of cStock as a mHealth strategy for improving data visibility and reducing stockouts of health products used at the community level. Additionally, the study will explore the added effects of the team approach deployed through EM in improving supply chain performance. Program description cStock is an SMS and web–based reporting and resupply system that is used by HSAs to report stock data via SMS through their personal mobile phones. cStock calculates HSA resupply quantities and sends this information to HF staff to use to pick and pack products for HSAs and notify them about a collection time. cStock was designed using a consultative, user–centered and iterative process. Potential users at all levels of the health system provided inputs based on their experience with the existing manual reporting and resupply system. Information on the existing flow of data across levels of the health system was combined with inputs from supply chain specialists to ensure the system was based on supply chain best practices. In designing the workflows and dashboard for cStock, an important criterion was to ensure the health care workers and managers at each level would have access to data most relevant to them, at the right time and in a format that could be easily accessed, interpreted and used for decision making. HSAs and HF staff would interact with cStock using SMS messages on their own phones, while district and central level staff would receive alert messages from cStock on their own phones. District and central level staff would use computers to access the web–based dashboard for reports. The dashboard was redesigned six months after implementation so that district and central level users could incorporate their experience interacting with the system into the redesign and prioritize metrics and visuals most useful for their day–to–day operations. cStock is a key component of both the EM and EPT intervention packages. The EM intervention addresses challenges related to data availability and visibility, as well as low motivation among HSAs while the EPT intervention addresses challenges of transport in addition to data visibility. The additional component of the EM intervention was District Product Availability Teams (DPATs). These are multilevel quality improvement teams that use data supplied by cStock to monitor performance of the supply chain and make informed supply chain decisions. In contrast, the additional component of the EPT intervention consisted of training all HSAs on bicycle maintenance, provision of a basic tool kit, and the use of a continuous review inventory control system. HSAs and HF staff in six districts where the project was piloted were trained on the use of cStock for reporting and resupply and used their own phones to register with cStock. Training was conducted using a cascade approach. The project trained a group of trainers consisting of central and district level staff from pilot districts as TOTs and they in turn trained the HSAs, HF and district staff. Both intervention groups were trained over a 2–day period, with one day dedicated to training users on how to register and use cStock. HSAs in the EM group were trained to send reports to cStock using a fixed monthly reporting schedule between the last day of the month and second day of the next month, while those in the EPT group were trained to send reports to cStock at any time during the month when they planned to travel to the HF giving them the flexibility to report and receive product. Once trained, HSAs were provided with job aids to carry back to their facilities and expected to start using cStock immediately. Implementation support for cStock was provided through group messages sent by the system administrator to users to correct common errors, automated messages sent directly by the system to users in response to formatting errors, and field visits made by Ministry and project staff to monitor and reinforce good practices. In designing the interventions, the project identified feasibility and acceptability of cStock as critical components to enhancing uptake and laying the foundation for country ownership and scalability. See Figure 1 for a visual representation of the intervention design. Figure 1 Components of the two intervention groups (EM – Enhanced Management and EPT – Efficient Product Transport). DPAT – district product availability teams.