4,504 results on '"Shu, Jiang"'
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2. Micromechanical characteristics and controlling mechanism of deep shale: a case study of well JYA in Pingqiao block, Fuling area
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Lingyun KONG, Guangpeng SONG, Shu JIANG, Zihang WANG, Jiqing LI, and Xian SHI
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micromechanical characteristics ,brittleness characteristics ,fracturing ,deep shale ,fuling area ,Geophysics. Cosmic physics ,QC801-809 ,Geology ,QE1-996.5 - Abstract
The deep shale gas in the Fuling area is characterized by complex structures, high crustal stress, significant stress differences, high formation temperatures, high compaction levels, low porosity, low permeability, and complex porosity-permeability variation patterns. One reason for the significant production differences between wells is the insufficient understanding of the geomechanical features and controlling mechanisms of deep shale gas reservoirs, and the inaccurate identification of sweet spots for hydraulic fracturing. This study focuses on the marine shale of the Wufeng-Longmaxi formations in the Fuling area, investigating the micromechanical characteristics and controlling mechanisms of deep shale gas reservoirs through five series of experiments: micro rock mechanics experiments, digital speckle experiments, X-ray diffraction, total organic carbon content measurement, and scanning electron microscopy (SEM). Coupled with digital image processing technology, the changes in stress field and displacement field, and microcrack propagation processes in the Longmaxi shale under loading conditions were meticulously depicted. The deformation and fracture characteristics of the Longmaxi shale were analyzed. Experimental results indicated that the total organic carbon content in the deep shale is approximately 4.2%, with quartz content at 55.4% and clay mineral at 26.9%. The study identified five stages of microdamage evolution in deep shale: compaction, elasticity, uniform crack propagation, crack propagation failure, and brittle failure. Under the influence of brittle minerals such as quartz, and soft components such as organic matter, the microcracks in deep shale exhibit various propagation modes, including transgranular, intergranular, and laminated layer cracks. Additionally, the fracture toughness indices of the deep shale samples were calculated, with Mode Ⅰ index being 8.279 $\mathrm{MPa} \cdot \sqrt{\mathrm{m}}$ and Mode Ⅱ index being 1.243 $\mathrm{MPa} \cdot \sqrt{\mathrm{m}}$. These experimentally obtained fracture toughness indices can be applied to evaluate the brittleness of deep shale, providing guidance for deep shale fracturing modification.
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- 2024
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3. Isolation and Identification of the Main Fungal Pathogens of Peach Fruit and the Antifungal Effect of Cinnamon Essential Oil on These Pathogens
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Mingxia YU, Yingying WEI, Zhengzheng HUANG, Yi CHEN, Shu JIANG, Feng XU, Hongfei WANG, and Xingfeng SHAO
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peach ,fungal pathogen ,cinnamon essential oil ,antifungal ,disease control ,Food processing and manufacture ,TP368-456 - Abstract
In 2020 and 2021, peach fruit with natural disease and decay were collected from orchards in Zhejiang Province. Then the fungal pathogens were isolated from the diseased spots and identified by morphological characteristics, molecular biological identification (rDNA-ITS sequence analysis) and pathogenicity detection. The antifungal effect of cinnamon essential oil on the fungal pathogens in vitro and in vivo were also investigated. The results showed that two fungal pathogens with strong pathogenicity were isolated, and identified as Monilinia fructicola and Rhizopus stolonifer, which caused brown rot and soft rot, respectively. Cinnamon essential oil inhibited the growth of M. fructicola and R. stolonifer, and the minimum inhibitory concentrations were 0.4 and 0.8 mL/L, respectively. M. fructicola was more sensitive to cinnamon essential oil. Cinnamon essential oil fumigation could reduce the disease incidence and lesion diameter of brown rot and soft rot of peach fruit caused by these two fungal pathogens. Therefore, cinnamon essential oil could be used as a natural fungicide to control fungal diseases of peach fruit.
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- 2024
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4. TPM4 acts as a potential predictor for the response to PD-1/PD-L1-inhibitor therapy in patients with glioblastoma
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Lirui Dai, Mahbub E Touhid, Peizhi Zhou, and Shu Jiang
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TPM4 ,Glioblastoma ,Immunotherapy ,Biomarker ,Surgery ,RD1-811 - Published
- 2024
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5. Development and Application of an Online Detection Device for Well Testing Steel Wire
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Tan, Jian, Li, Guo, Yang, Jian, Wang, Ke, Tang, Guang-hua, Wen, Shu-jiang, Wu, Wei, Series Editor, and Lin, Jia'en, editor
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- 2024
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6. Study on Key Technologies of Geosteering for Shale Gas Horizontal Wells in the Complex Structural Area of Block H in Western Hubei-Eastern Chongqing
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Wenrui Shi, Yijiang Feng, Hongyan Zhao, Zisang Huang, Meiyu Guo, Shu Jiang, Yawen Li, Hua Huang, and Yuanhui Shi
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Chemistry ,QD1-999 - Published
- 2024
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7. FMDNN: A Fuzzy-Guided Multigranular Deep Neural Network for Histopathological Image Classification.
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Weiping Ding 0001, Tianyi Zhou 0001, Jiashuang Huang, Shu Jiang, Tao Hou, and Chin-Teng Lin
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- 2024
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8. Entity-Relation Extraction as Full Shallow Semantic Dependency Parsing.
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Shu Jiang, Zuchao Li, Hai Zhao 0001, and Weiping Ding 0001
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- 2024
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9. Causal associations of COVID‐19 on neurosurgical diseases risk: a Mendelian randomization study
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Lirui Dai, Liang Lyu, Peizhi Zhou, and Shu Jiang
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Neurosurgical disorders ,COVID‐19 ,Genetic variants ,Genome‐wide association study ,Mendelian randomization ,Medicine ,Genetics ,QH426-470 - Abstract
Abstract Many researchers have explored the potential association between one neurosurgical disease and coronavirus disease 2019 (COVID-19), but few systematically analyzed the association and causality between COVID-19 and various neurosurgical diseases. A Mendelian randomization analysis was conducted to evaluate the causal association between COVID-19 (including critically ill COVID‐19, hospitalized COVID‐19, and respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection) and 30 neurosurgical diseases within European populations. The consequences of inverse variance weighted models suggest that genetic susceptibility of critically ill COVID-19 may increase the risk of cerebral infarction (odds ratio [OR] = 1.02; p‐value = 0.006), genetic susceptibility of SARS-CoV-2 infection may increase the risk of stroke (OR = 1.02; p‐value = 0.047), and conversely, genetic susceptibility of hospitalized COVID-19 may reduce the risk of pituitary adenoma and craniopharyngioma (OR = 0.90; p‐value = 0.032). In addition, evidences revealed potential associations between genetic susceptibility of COVID-19 and spinal stenosis (OR = 1.03; p‐value = 0.028), diffuse brain injury (OR = 1.21; p‐value = 0.040) and focal brain injury (OR = 1.12; p‐value = 0.040). By testing for heterogeneity and pleiotropy, the above causal conclusions are robust. In summary, our analysis shows that COVID-19 has an independent and powerful causal influence on multiple neurosurgical disorders.
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- 2024
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10. Identification and evaluation of shale oil micro-migration and its petroleum geological significance
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Tao HU, Fujie JIANG, Xiongqi PANG, Yuan LIU, Guanyun WU, Kuo ZHOU, Huiyi XIAO, Zhenxue JIANG, Maowen LI, Shu JIANG, Liliang HUANG, Dongxia CHEN, and Qingyang MENG
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shale oil ,micro-migration identification ,micro-migration evaluation ,Junggar Basin ,Mahu Sag ,Lower Permian ,Petroleum refining. Petroleum products ,TP690-692.5 - Abstract
Taking the Lower Permian Fengcheng Formation shale in Mahu Sag of Junggar Basin, NW China, as an example, core observation, test analysis, geological analysis and numerical simulation were applied to identify the shale oil micro-migration phenomenon. The hydrocarbon micro-migration in shale oil was quantitatively evaluated and verified by a self-created hydrocarbon expulsion potential method, and the petroleum geological significance of shale oil micro-migration evaluation was determined. Results show that significant micro-migration can be recognized between the organic-rich lamina and organic-poor lamina. The organic-rich lamina has strong hydrocarbon generation ability. The heavy components of hydrocarbon preferentially retained by kerogen swelling or adsorption, while the light components of hydrocarbon were migrated and accumulated to the interbedded felsic or carbonate organic-poor laminae as free oil. About 69% of the Fengcheng Formation shale samples in Well MY1 exhibit hydrocarbon charging phenomenon, while 31% of those exhibit hydrocarbon expulsion phenomenon. The reliability of the micro-migration evaluation results was verified by combining the group components based on the geochromatography effect, two-dimension nuclear magnetic resonance analysis, and the geochemical behavior of inorganic manganese elements in the process of hydrocarbon migration. Micro-migration is a bridge connecting the hydrocarbon accumulation elements in shale formations, which reflects the whole process of shale oil generation, expulsion and accumulation, and controls the content and composition of shale oil. The identification and evaluation of shale oil micro-migration will provide new perspectives for dynamically differential enrichment mechanism of shale oil and establishing a “multi-peak model in oil generation” of shale.
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- 2024
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11. Utilization of carbon catabolite repression for efficiently biotransformation of anthraquinone O-glucuronides by Streptomyces coeruleorubidus DM
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Chen Tao, Quyi Wang, Junyang Ji, Ziyue Zhou, Bingjie Yue, Ran Zhang, Shu Jiang, and Tianjie Yuan
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anthraquinone ,glucuronidation ,Streptomyces ,biotransformation ,carbon catabolite repression ,Microbiology ,QR1-502 - Abstract
Carbon catabolite repression (CCR) is a highly conserved mechanism that regulates carbon source utilization in Streptomyces. CCR has a negative impact on secondary metabolite fermentation, both in industrial and research settings. In this study, CCR was observed in the daunorubicin (DNR)-producing strain Streptomyces coeruleorubidus DM, which was cultivated in high concentration of carbohydrates. Unexpectedly, DM exhibited a high ability for anthraquinone glucuronidation biotransformation under CCR conditions with a maximum bioconversion rate of 95% achieved at pH 6, 30°C for 24 h. The co-utilization of glucose and sucrose resulted in the highest biotransformation rate compared to other carbon source combinations. Three novel anthraquinone glucuronides were obtained, with purpurin-O-glucuronide showing significantly improved water solubility, antioxidant activity, and antibacterial bioactivity. Comparative transcript analysis revealed that glucose and sucrose utilization were significantly upregulated as DM cultivated under CCR condition, which strongly enhance the biosynthetic pathway of the precursors Uridine diphosphate glucuronic acid (UDPGA). Meanwhile, the carbon metabolic flux has significantly enhanced the fatty acid biosynthesis, the exhaust of acetyl coenzyme A may lead to the complete repression of the biosynthesis of DNR, Additionally, the efflux transporter genes were simultaneously downregulated, which may contribute to the anthraquinones intracellular glucuronidation. Overall, our findings demonstrate that utilizing CCR can be a valuable strategy for enhancing the biotransformation efficiency of anthraquinone O-glucuronides by DM. This approach has the potential to improve the bioavailability and therapeutic potential of these compounds, opening up new possibilities for their pharmaceutical applications.
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- 2024
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12. Pd(II)/N,N′-Disulfonyl bisimidazoline-catalyzed asymmetric arylation of isoquinoline-1,3,4-trione-derived ketimines
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Miao, An-Qi, Wang, Yu-Xin, Xu, Lin-Lin, Hao, Wen-Juan, Tu, Shu-Jiang, Zhang, Jin-Peng, and Jiang, Bo
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- 2024
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13. Systematic analysis based on the cuproptosis-related genes identifies ferredoxin 1 as an immune regulator and therapeutic target for glioblastoma
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Lirui Dai, Peizhi Zhou, Liang Lyu, and Shu Jiang
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Glioblastoma ,Cuproptosis ,Prognostic model ,Drug ,FDX1 ,Immune infiltration ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Glioblastoma multiforme (GBM) is recognized as the prevailing malignant and aggressive primary brain tumor, characterized by an exceedingly unfavorable prognosis. Cuproptosis, a recently identified form of programmed cell death, exhibits a strong association with cancer progression, therapeutic response, and prognostic outcomes. However, the specific impact of cuproptosis on GBM remains uncertain. To address this knowledge gap, we obtained transcriptional and clinical data pertaining to GBM tissues and their corresponding normal samples from various datasets, including TCGA, CGGA, GEO, and GTEx. R software was utilized for the analysis of various statistical techniques, including survival analysis, cluster analysis, Cox regression, Lasso regression, gene enrichment analysis, drug sensitivity analysis, and immune microenvironment analysis. Multiple assays were conducted to investigate the expression of genes related to cuproptosis and their impact on the proliferation, invasion, and migration of glioblastoma multiforme (GBM) cells. The datasets were obtained and prognostic risk score models were constructed and validated using differentially expressed genes (DEGs) associated with cuproptosis. To enhance the practicality of these models, a nomogram was developed.Patients with glioblastoma multiforme (GBM) who were classified as high risk exhibited a more unfavorable prognosis and shorter overall survival compared to those in the low risk group. Additionally, we specifically chose FDX1 from the differentially expressed genes (DEGs) within the high risk group to assess its expression, prognostic value, biological functionality, drug responsiveness, and immune cell infiltration. The findings demonstrated that FDX1 was significantly upregulated and associated with a poorer prognosis in GBM. Furthermore, its elevated expression appeared to be linked to various metabolic processes and the susceptibility to chemotherapy drugs. Moreover, FDX1 was found to be involved in immune cell infiltration and exhibited correlations with multiple immunosuppressive genes, including TGFBR1 and PDCD1LG2. The aforementioned studies offer substantial assistance in informing the chemotherapy and immunotherapy approaches for GBM. In summary, these findings contribute to a deeper comprehension of cuproptosis and offer novel perspectives on the involvement of cuproptosis-related genes in GBM, thereby presenting a promising therapeutic strategy for GBM patients.
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- 2023
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14. Pore structure and pore size change for tight sandstone treated with supercritical CO2 fluid
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Xian Shi, Caiyun Xiao, Hongjian Ni, Qi Gao, Lei Han, Dianshi Xiao, and Shu Jiang
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Supercritical CO2 ,Tight sandstone ,Pore structure ,NMR ,HPMI ,Electrical engineering. Electronics. Nuclear engineering ,TK1-9971 - Abstract
The effects of ScCO2 on pore structure should be investigated in order to properly apply supercritical carbon dioxide (ScCO2) fracturing on tight sandstone. ScCO2 treatment was applied to three sets of tight sandstone samples. The pore structure was characterized using a combination of high-pressure mercury intrusion porosimetry and nuclear magnetic resonance. Furthermore, the pore size distribution’s multi-fractal dimensions were estimated. After SCCO2 treatment, the number of transitional pores decreased significantly, while the number of mesopores and macropores increased. At all scales, the fractal dimension characteristics indicate that pore structure gets more complicated and heterogeneous. Furthermore, due to their larger contact area, large pores have a higher fractal dimension than small pores. The accumulative pore volume of the calcite-rich group increases and a decreasing trend occurs for the calcite-rare group. The content of calcite sharply decreased while clay, feldspar, and plagioclase content have a slight drop after ScCO2 treatment, which affects the alternation of pore structure. Thus, the accumulative porosity volume and pore connectivity do not always increase after ScCO2 exposure because re-precipitation and fine migration can potentially clog pores and channels.
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- 2023
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15. FMDNN: A Fuzzy-guided Multi-granular Deep Neural Network for Histopathological Image Classification.
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Weiping Ding 0001, Tianyi Zhou 0001, Jiashuang Huang, Shu Jiang, Tao Hou, and Chin-Teng Lin
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- 2024
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16. Editorial for Special Issue: 'Stem Cell-Derived Organoids'
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Yujing Li, Xuekun Li, Yunhee Kang, and Shu Jiang
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Internal medicine ,RC31-1245 - Published
- 2024
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17. Effect of Soybean Meal Proteins on Gel Properties of Silver Carp Surimi
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Fang WU, Shu JIANG, Manzi HU, Bei LIU, Haiying LUO, and Ting HU
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soybean meal protein ,surimi ,gel characteristics ,chemical forces ,secondary structure ,Food processing and manufacture ,TP368-456 - Abstract
The influence of soybean meal protein addition to the gel properties of silver carp surimi was studied, and the potential causes were further analyzed from the perspective of chemical forces and protein secondary structures. The surimi gels were prepared by the addition of 0%, 0.5%, 1.0%, 1.5% and 2.0% of soybean meal protein, respectively, to the frozen surimi samples of silver carp. The water-holding capacity, cooking loss rate, whiteness value, texture characteristics, sensory quality, chemical strength, total sulfhydryl content and protein secondary structure of surimi gel were measured by a texture analyzer and Fourier transform infrared spectrometer. The results showed that when the amount of soybean meal protein accounted for 1.5% of the frozen silver carp surimi, the water holding capacity, hardness, springiness, cohesiveness and chewiness of the surimi gel increased to the maximum values of 87.59%±1.44%, 381.70±7.64 g, 12.41±0.67 mm, 0.89±0.02 and 38.60±0.14 mJ, respectively, while the cooking loss rate decreased to the minimum value of 10.20%±0.52%, the sensory quality reached the best, and the whiteness value decreased slightly. This could be explained that the addition of 1.5% soybean meal protein led to a maximum hydrophobic interaction and total sulfhydryl content of surimi gel, and a tight gel three-dimensional network structure was formed. Moreover, the addition of soybean meal protein had little effect on the secondary structure of surimi protein. Therefore, the addition of 1.5% soybean meal protein effectively improved the gelation properties of surimi products.
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- 2023
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18. Endovascular treatment in bilateral cavernous sinus dural arteriovenous fistulas: a systematic review and meta-analysis
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Pang-Shuo Perng, Yu Chang, Yuan-Ting Sun, Hao-Kuang Wang, Yu-Shu Jiang, Jung-Shun Lee, Liang-Chao Wang, and Chih-Yuan Huang
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Medicine ,Science - Abstract
Abstract Few studies have discussed the disease nature and treatment outcomes for bilateral cavernous sinus dural arteriovenous fistula (CSDAVF). This study aimed to investigate the clinical features and treatment outcomes of bilateral CSDAVF. Embase, Medline, and Cochrane library were searched for studies that specified the outcomes of bilateral CSDAVF from inception to April 2022. The classification, clinical presentation, angiographic feature, surgical approach, and treatment outcomes were collected. Meta-analysis was performed using the random effects model. Eight studies reporting 97 patients were included. The clinical presentation was mainly orbital (n = 80), cavernous (n = 52) and cerebral (n = 5) symptoms. The most approached surgical route was inferior petrosal sinus (n = 80), followed by superior orbital vein (n = 10), and alternative approach (n = 7). Clinical symptoms of 88% of the patients (95% CI 80–93%, I2 = 0%) were cured, and 82% (95% CI 70–90%, I2 = 7%) had angiographic complete obliteration of fistulas during follow up. The overall complication rate was 18% (95% CI 11–27%, I2 = 0%). Therefore, endovascular treatment is an effective treatment for bilateral CSDAVF regarding clinical or angiographic outcomes. However, detailed evaluation of preoperative images and comprehensive surgical planning of the approach route are mandatory owing to complexity of the lesions.
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- 2023
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19. Adherence to healthy diet and risk of cardiovascular disease in adult survivors of childhood cancer in the St. Jude Lifetime Cohort: a cross-sectional study
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Tuo Lan, Mei Wang, Matthew J. Ehrhardt, Shu Jiang, Jennifer Q. Lanctot, Gregory T. Armstrong, Melissa M. Hudson, Graham A. Colditz, Leslie L. Robison, and Yikyung Park
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Dietary patterns ,Cardiovascular disease ,Childhood cancer survivor ,Health Eating Index ,DASH ,Mediterranean diet ,Medicine - Abstract
Abstract Background Whether diet has beneficial effects on cardiovascular disease (CVD) in childhood cancer survivors as in the general population is unknown. Therefore, we examined associations between dietary patterns and risk of CVD in adult survivors of childhood cancer. Methods Childhood cancer survivors, 18–65 years old in the St Jude Lifetime Cohort (1882 men and 1634 women) were included in the analysis. Dietary patterns were defined by the adherence to the Healthy Eating Index (HEI)–2015, Dietary Approaches to Stop Hypertension (DASH), and alternate Mediterranean diet (aMED) based on a food frequency questionnaire at study entry. CVD cases (323 in men and 213 in women) were defined as participants with at least one grade 2 or higher CVD-related diagnosis at baseline. Multivariable logistic regression adjusted for confounders was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs) of CVD. Results Greater adherence to HEI-2015 (OR=0.88, 95% CI: 0.75–1.03, per 10 score increment), DASH (OR=0.85, 95% CI: 0.71–1.01, per 10 score increment), and aMED (OR=0.92, 95% CI: 0.84–1.00, each score increment) were, albeit trending towards significance, associated with a lower risk of CVD in women. HEI-2015 was associated with a non-significantly lower risk of CVD in men (ORQ5 vs. Q1=0.80, 95% CI: 0.50–1.28). These dietary patterns were also associated with a lower risk of CVD in survivors with high underlying CVD risk. Conclusions As recommended to the general population, a diet rich in plant foods and moderate in animal foods needs to be a part of CVD management and prevention in childhood cancer survivors.
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- 2023
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20. Paleoenvironment and Hydrocarbon Potential of Salinized Lacustrine Shale with High Terrigenous Input in the Paleogene Biyang Depression (East China): Evidence from Organic Petrography and Geochemistry
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Yu Song, Paerzhana Paerhati, Shilin Xu, Shu Jiang, Bo Gao, Shuifu Li, Qiang Cao, Zhonghui Li, Li Wan, and Chuang Li
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lacustrine organic-rich shale ,paleo-saline lake ,biomarkers ,elemental geochemistry ,deep resource exploration ,Technology - Abstract
Salinized lacustrine shale (SLS) represents a frontier in the global quest for unconventional hydrocarbon resources. The impact of terrigenous input, which includes terrigenous organic matter (OM) and detrital matter, on the deposition and hydrocarbon potential of SLS is still controversial. Here, we examine this issue using the newly discovered SLS within the Paleogene Biyang Depression, employing a combination of organic petrographic and geochemical analyses. A high influx of terrigenous input (terrigenous OM and detrital matter) promotes the formation of SLS. On the one hand, terrigenous higher plants emerge as the primary source of OM in the SLS, as indicated by the dominance of terrigenous macerals (e.g., terrigenous liptinite) and the abundance of plant-derived biomarkers (e.g., tricyclic terpanes). Additionally, a portion of the OM may originate from bacteria. On the other hand, the rapid input of detrital matter improves the preservation of OM, resulting in the deposition of SLS with high total organic carbon (TOC) contents and low hydrogen index (HI) values. The findings of this study contribute to a deeper understanding of SLS deposition and provide guidance for regional hydrocarbon exploration.
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- 2024
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21. Study on the Identification, Failure Mode, and Spatial Distribution of Bank Collapses after the Initial Impoundment in the Head Section of Baihetan Reservoir in Jinsha River, China
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Chuangchuang Yao, Lingjing Li, Xin Yao, Renjiang Li, Kaiyu Ren, Shu Jiang, Ximing Chen, and Li Ma
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Baihetan Reservoir ,bank collapse ,bank collapse identification ,bank failure mode ,distribution laws ,Science - Abstract
After the initial impoundment of the Baihetan Reservoir in April 2021, the water level in front of the dam rose about 200 m. The mechanical properties and effects of the bank slopes in the reservoir area changed significantly, resulting in many bank collapses. This study systematically analyzed the bank slope of the head section of the reservoir, spanning 30 km from the dam to Baihetan Bridge, through a comprehensive investigation conducted after the initial impoundment. The analysis utilized UAV flights and ground surveys to interpret the bank slope’s distribution characteristics and failure patterns. A total of 276 bank collapses were recorded, with a geohazard development density of 4.6/km. The slope gradient of 26% of the collapsed banks experienced an increase ranging from 5 to 20° after impoundment, whereas the remaining sites’ inclines remained unchanged. According to the combination of lithology and movement mode, the bank failure mode is divided into six types, which are the surface erosion type, surface collapse type, surface slide type, bedding slip type of clastic rock, toppling type of clastic rock, and cavity corrosion type of carbonate rock. It was found that the collapsed banks in the reservoir area of 85% developed in the reactivation of old landslide deposits, while 15% in the clastic and carbonate rock. This study offers guidance for the next phase of bank collapse regulations and future geohazards prevention strategies in the Baihetan Reservoir area.
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- 2024
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22. Abandonment and Recovery Operation of Steel Lazy-Wave Riser in Deep-water by Controlled Vessel and Cable Velocity Rate
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Gu, Ji-jun, Huang, Jun, Gao, Lei, Chen, Lei-lei, Jia, Ji-chuan, and Wang, Shu-jiang
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- 2023
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23. Deformation response and mechanical analysis of the Wangjiashan landslide in Baihetan Hydropower Station, China, during initial impoundment
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Xiaoting, Chen, Renjiang, Li, Bin, Hu, Yueping, Yin, Jianyuan, Yang, Shu, Jiang, Panpan, Qin, and Bolin, Huang
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- 2023
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24. Lessons learned from hydrothermal to hot dry rock exploration and production
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Shu Jiang, Kai Zhang, Joseph Moore, and John McLennan
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Geothermal lessons ,Hydrothermal system ,Hot dry rock ,Hydraulic fracturing ,Enhanced geothermal recovery ,Closed-loop ,Production of electric energy or power. Powerplants. Central stations ,TK1001-1841 - Abstract
In this paper, we investigate geothermal exploration and production in 189 hydrothermal projects and 42 hot dry rock projects around the world. The hydrothermal fields for a working hydrothermal system to generate electricity should have the elements of heat source, water-saturated porous or fractured reservoir, caprock, heat transfer pathway, and good heat preservation condition and geothermal power energy intensity of 10–20 MW per km2 within at least 5 km2 area in tectonically active region. The hot water or steam flow rate in this hydrothermal system is normally larger than 40 L/s with temperature of 150 °C or above. The power generated from enhanced geothermal system (EGS) in hot dry rock projects are generally less than 2 MW because the flow rate in most cases is much less than 40 L/s even with the hydraulic fractures using the modern stimulation technology learned from the oil and gas industry. The natural fracture in the subsurface is generally beneficial to the hydraulic fracturing and heat recovery in the hot dry rock. Moreover, the hydraulic fracture parameters, injection rate and well spacing, drilling strategy should be properly designed to avoid the short-circuit between injector and producer and low heat productivity. In the future, CO2 enhanced geothermal recovery associated with CO2 sequestration in the high temperature oil, gas, and geothermal fields maybe a good choice. On the other hand, both near-real-time seismic monitoring to limit the pumping rate and the closed-loop of the Eavor-Loop style system without hydraulic fracture can contribute greatly to heat recovery of hot dry rocks and mitigate the risks of the hydraulic fracturing induced earthquake. Furthermore, the hybrid solar and geothermal system performs better than the stand-alone geothermal system.
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- 2023
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25. Advances in geothermal exploration and production: Introduction
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Zhiliang He, Shu Jiang, Haibing Shao, and Bo Feng
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Production of electric energy or power. Powerplants. Central stations ,TK1001-1841 - Published
- 2023
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26. Palladium-catalyzed annulative allylic alkylation for regioselective construction of indole-fused medium-sized cyclic ethers
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Chen, Ling-Qi, Zhu, Chi-Fan, Zhang, Su, Liu, Bao-Yang, Tu, Shu-Jiang, Hao, Wen-Juan, and Jiang, Bo
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- 2023
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27. Millimeter Wave Planar Wideband Circularly Polarized Antenna Loaded Triangular Patch for End-Fire Radiation.
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Hengfei Xu, Boyu Sima, Pu Wei, Lei Tang, Shu Jiang, and Chuanqing Liu
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- 2023
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28. An infrared and visible image fusion using knowledge measures for intuitionistic fuzzy sets and Swin Transformer.
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Muhammad Jabir Khan, Shu Jiang, Weiping Ding 0001, Jiashuang Huang, and Haipeng Wang
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- 2024
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29. Pheromone-guided parallel rough hypercuboid attribute reduction algorithm.
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Weiping Ding 0001, Hongcheng Yao, Hengrong Ju, Jiashuang Huang, Shu Jiang, and Yuepeng Chen
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- 2024
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30. Establishing a high-efficiency in vitro regeneration system for Agrobacterium-mediated transformation in Fragaria nilgerrensis
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Shu Jiang, Yi Ji, Mingqian Wang, Li Xue, Jun Zhao, Yang Zheng, Hanping Dai, and Jiajun Lei
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regeneration ,genetic transformation ,fragaria nilgerrensis ,strawberry ,Plant culture ,SB1-1110 - Abstract
Fragaria nilgerrensis Schlechtendal ex J. Gay, a diploid wild strawberry, has many excellent characteristics such as fruit with white color and peach fragrance, and strong disease resistance. However, the lack of an efficient and stable regeneration and genetic transformation system for F. nilgerrensis has largely limited the functional studies of related genes governing excellent traits. In this study, a regeneration system for F. nilgerrensis leaf discs was developed by optimizing factors such as different hormone combinations, dark culture times and casein hydrolysate (CH) concentrations, with an average regeneration rate of 97.3% at 45 d of culture. By paraffin section observation of callus with different colors induced from the leaf disc regeneration, light yellow callus was determined to be embryogenic and the regenerative pathway was identified as indirect organogenesis. Based on this, an average transformation percentage of 8.67% was achieved by screening kanamycin concentration and referring to transformation procedures described by predecessors. PCR-positive transformants were obtained within 4−5 months by confirmation of PCR and histochemical GUS, and transgene integration was identified by transformants regeneration. The establishment of an efficient regeneration system provided a feasible platform for genetic transformation, which provided the foundation for further gene functional studies in F. nilgerrensis.
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- 2023
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31. Which surgery is better for obese patients with lumbar degenerative diseases: open TLIF or Endo-LIF? A retrospective matched case–control study
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Shen, Xu, Zhang, Pei, Gao, Yu-cheng, Xuan, Wen-bin, Wang, Feng, Song, Peng, Wang, Shu-jiang, and Gao, Zeng-xin
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- 2023
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32. Inetetamab in combination with rapamycin and chemotherapy for trastuzumab‐treated metastatic human epidermal growth factor receptor 2‐positive breast cancer with abnormal activation of PI3K/Akt/mTOR pathway
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Aijuan Wang, Chenghui Li, Qi'an Jiang, and Shu Jiang
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anti‐HER‐2 therapy ,breast cancer ,human epidermal growth factor receptor 2 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Human epidermal growth factor receptor 2 (HER2) overexpression is an independent prognostic factor of poor prognosis and a predictor of efficacy of anti‐HER2 therapy. A limited number of patients can receive standard second‐line therapy (DS‐8201 or T‐DM1) for metastatic HER2‐positive in some parts of the world, including China, due to many factors, such as cost–benefit ratios. Case A 51‐year‐old premenopausal woman was diagnosed with HER2‐positive breast cancer. The pathological stage was ypT3N2M0 and stage IIIA. Trastuzumab targeted therapy combined with goserelin depot was started along with letrozole endocrine therapy. After eight courses of treatment, magnetic resonance imaging (MRI) examination revealed new multiple metastases in the liver, and progression disease (PD) was evaluated. Due to abnormal activation of the phosphatidylinositol 3‐kinase/protein kinase B/mammalian target of rapamycin (PI3K/AKT/mTOR) pathway in the patient, treatment was changed to the mammalian target of rapamycin (mTOR) inhibitor combined with the anti‐HER‐2 agents inetetamab and paclitaxel, while partial response (PR) was evaluated after 6 cycles of treatment. As the patient was hormone receptor (HR) positive, treatment was changed to the inetetamab + rapamycin + exemestane regimen. The lesion continued to shrink and PR was evaluated for 8 cycles. The original regimen was continued, PR was evaluated after 12 courses of treatment. The abdominal MRI performed showed an increase in the volume of intrahepatic multiple metastatic tumor lesion. Efficacy was used to assess for PD and the progression‐free survival (PFS) was 317 days. Conclusion A phosphatidylinositol‐4, 5‐bisphosphate 3‐kinase catalytic subunit alpha (PIK3CA) mutation in trastuzumab‐treated metastatic HER2‐positive breast cancer female had a long PFS by treating with the mammalian target of rapamycin inhibitor in combination with the anti‐HER‐2 agent inetetamab.
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- 2023
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33. Insights into cryptic speciation of quillworts in China
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Gu, Yu-Feng, Shu, Jiang-Ping, Lu, Yi-Jun, Shen, Hui, Shao, Wen, Zhou, Yan, Sun, Qi-Meng, Chen, Jian-Bing, Liu, Bao-Dong, and Yan, Yue-Hong
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- 2023
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34. Deep Learning Based Algae Detection Method.
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Ziye Fang, Shu Jiang, Xiaoyu Du, and Zechao Li
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- 2022
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35. Psychological Health and Self-management During Epidemic Control
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Luo, Yu, Shu, Jiang, Liu, Qian, Li, Mengxi, Yao, Xuechen, Angrisani, Leopoldo, Series Editor, Arteaga, Marco, Series Editor, Panigrahi, Bijaya Ketan, Series Editor, Chakraborty, Samarjit, Series Editor, Chen, Jiming, Series Editor, Chen, Shanben, Series Editor, Chen, Tan Kay, Series Editor, Dillmann, Rüdiger, Series Editor, Duan, Haibin, Series Editor, Ferrari, Gianluigi, Series Editor, Ferre, Manuel, Series Editor, Hirche, Sandra, Series Editor, Jabbari, Faryar, Series Editor, Jia, Limin, Series Editor, Kacprzyk, Janusz, Series Editor, Khamis, Alaa, Series Editor, Kroeger, Torsten, Series Editor, Li, Yong, Series Editor, Liang, Qilian, Series Editor, Martín, Ferran, Series Editor, Ming, Tan Cher, Series Editor, Minker, Wolfgang, Series Editor, Misra, Pradeep, Series Editor, Möller, Sebastian, Series Editor, Mukhopadhyay, Subhas, Series Editor, Ning, Cun-Zheng, Series Editor, Nishida, Toyoaki, Series Editor, Pascucci, Federica, Series Editor, Qin, Yong, Series Editor, Seng, Gan Woon, Series Editor, Speidel, Joachim, Series Editor, Veiga, Germano, Series Editor, Wu, Haitao, Series Editor, Zamboni, Walter, Series Editor, Zhang, Junjie James, Series Editor, Long, Shengzhao, editor, and Dhillon, Balbir S., editor
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- 2022
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36. Studies of parenchymal texture added to mammographic breast density and risk of breast cancer: a systematic review of the methods used in the literature
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Akila Anandarajah, Yongzhen Chen, Graham A. Colditz, Angela Hardi, Carolyn Stoll, and Shu Jiang
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Breast density ,Mammography ,Parenchymal patterns ,Risk prediction ,Texture ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract This systematic review aimed to assess the methods used to classify mammographic breast parenchymal features in relation to the prediction of future breast cancer. The databases including Medline (Ovid) 1946-, Embase.com 1947-, CINAHL Plus 1937-, Scopus 1823-, Cochrane Library (including CENTRAL), and Clinicaltrials.gov were searched through October 2021 to extract published articles in English describing the relationship of parenchymal texture features with the risk of breast cancer. Twenty-eight articles published since 2016 were included in the final review. The identification of parenchymal texture features varied from using a predefined list to machine-driven identification. A reduction in the number of features chosen for subsequent analysis in relation to cancer incidence then varied across statistical approaches and machine learning methods. The variation in approach and number of features identified for inclusion in analysis precluded generating a quantitative summary or meta-analysis of the value of these features to improve predicting risk of future breast cancers. This updated overview of the state of the art revealed research gaps; based on these, we provide recommendations for future studies using parenchymal features for mammogram images to make use of accumulating image data, and external validation of prediction models that extend to 5 and 10 years to guide clinical risk management. Following these recommendations could enhance the applicability of models, helping improve risk classification and risk prediction for women to tailor screening and prevention strategies to the level of risk.
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- 2022
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37. Azoarene activation for Schmidt-type reaction and mechanistic insights
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Fan-Tao Meng, Ya-Nan Wang, Xiao-Yan Qin, Shi-Jun Li, Jing Li, Wen-Juan Hao, Shu-Jiang Tu, Yu Lan, and Bo Jiang
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Science - Abstract
The Schmidt reaction enables nitrogen insertion across an aldehyde or ketone substrate by frequently using azide reagents. Here, the authors show a Schmidt reaction of aryldiazonium salts as a replacement of azide reagents to access skeletally diverse cyclic lactams.
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- 2022
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38. The associations of serum valine with mild cognitive impairment and Alzheimer’s disease
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Xiong, Yong-lan, Therriault, Joseph, Ren, Shu-jiang, Jing, Xiao-jun, and Zhang, Hua
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- 2022
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39. Seismic attribute characteristics of an ultradeep fractured-reservoir in the northern section of Shunbei No.5 strike-slip fault zone in Tarim Basin
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Jun Liu, Wei Gong, Chao Huang, Wei Li, Hongyan Li, Xiaobin Dong, and Shu Jiang
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faults and fracture ,ultradeep carbonatite reservoir ,fracture density ,seismic attribute ,strike-slip fault zone ,tarim basin ,Geology ,QE1-996.5 ,Engineering geology. Rock mechanics. Soil mechanics. Underground construction ,TA703-712 - Abstract
The Shunbei No. 5 strike-slip fault and its associated fractures in Tarim Basin control the formation of reservoirs and impact the migration and accumulation of oil and gas. Selecting appropriate seismic attributes to characterize and describe the spatial distribution of fractured reservoirs plays an important role in fractured reservoir prediction. Due to the seismic resolution of faults and fractures at different scales, it is necessary to use different methods and their combinations to identify fractures at different scales. To further characterize the fractures that associated with strike-slip faults in the Shunbei area in Tarim Basin, this paper compares the capability characterizing faults and fractures of individual seismic attributes and their combined attributes.The seismic attribute comparison shows that the high-precision coherent volume that constrained by dip angle and plane feature attribute can characterize the large-scale faults with fault distances over 40 m.The multi-coherent merge and strain-energy attributes can represent mesoscale fractures with a fault distance of 40-15 m. In addition, fracture-gave gain and thin likelihood enhancer can characterize small-scale fractures with a fault distance less than 15 m.The results of correlation fitting of typical seismic attributes to actual fracture data and fracture density curves that interpreted from EMI imaging logging were ranked.Finally, four seismic attributes including chaos, planes, third component of structural tensor, and frequency division coherence fusion are optimized for fracture density calculation.The calculated results show that the potential reservoirs that associated with the high-density fracture zone is mainly located within 1.5 km of the transpression section of the fault in the upper section of the lower to middle Ordovician Yingshan Formation.
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- 2022
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40. Multimode tunable terahertz absorber based on a quarter graphene disk structure
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Zhibin Ye, Pinghui Wu, Hailun Wang, Shu Jiang, Meng Huang, Dongge Lei, and Fei Wu
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Graphene ,Tunable ,Perfect absorption ,FDTD solution ,Terahertz ,Physics ,QC1-999 - Abstract
In this research work, in order to solve the unadjustability of traditional noble metal absorbers to meet the complex application requirements in the actual electromagnetic environment, we designed a simple tunable absorber based on graphene with tunable Fermi level. The performance of the proposed absorber is theoretically simulated by the finite difference time domain (FDTD) method. The proposed absorber has two perfect absorption peaks with high efficiency of 99.51% and 99.548% in its working band (90–155 μm). We have performed an in-depth analysis of the causes of perfect absorption and focused on the tunability of the absorber. The absorption frequency can be adjusted by controlling the relaxation time and Fermi level of graphene, and the same purpose can be achieved by changing the refractive index (relative dielectric constant) of the medium. In addition, we also explored the influence of the change of the top structure parameters on the absorption performance. The proposed absorber has the ability to adapt to different electromagnetic environments. In general, it can be flexibly regulated in practical applications, which will provide new possibilities for the development of many fields such as detection and communication.
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- 2023
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41. How About Vanadium‐Based Compounds as Cathode Materials for Aqueous Zinc Ion Batteries?
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Tingting Lv, Yi Peng, Guangxun Zhang, Shu Jiang, Zilin Yang, Shengyang Yang, and Huan Pang
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aqueous zinc‐ion batteries ,cathode materials ,vanadium‐based compounds ,Science - Abstract
Abstract Aqueous zinc‐ion batteries (AZIBs) stand out among many monovalent/multivalent metal‐ion batteries as promising new energy storage devices because of their good safety, low cost, and environmental friendliness. Nevertheless, there are still many great challenges to exploring new‐type cathode materials that are suitable for Zn2+ intercalation. Vanadium‐based compounds with various structures, large layer spacing, and different oxidation states are considered suitable cathode candidates for AZIBs. Herein, the research advances in vanadium‐based compounds in recent years are systematically reviewed. The preparation methods, crystal structures, electrochemical performances, and energy storage mechanisms of vanadium‐based compounds (e.g., vanadium phosphates, vanadium oxides, vanadates, vanadium sulfides, and vanadium nitrides) are mainly introduced. Finally, the limitations and development prospects of vanadium‐based compounds are pointed out. Vanadium‐based compounds as cathode materials for AZIBs are hoped to flourish in the coming years and attract more and more researchers' attention.
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- 2023
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42. MOFs Containing Solid‐State Electrolytes for Batteries
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Shu Jiang, Tingting Lv, Yi Peng, and Huan Pang
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composites ,metal–organic frameworks ,solid‐state batteries ,solid‐state electrolytes ,Science - Abstract
Abstract The use of metal–organic frameworks (MOFs) in solid‐state electrolytes (SSEs) has been a very attractive research area that has received widespread attention in the modern world. SSEs can be divided into different types, some of which can be combined with MOFs to improve the electrochemical performance of the batteries by taking advantage of the high surface area and high porosity of MOFs. However, it also faces many serious problems and challenges. In this review, different types of SSEs are classified and the changes in these electrolytes after the addition of MOFs are described. Afterward, these SSEs with MOFs attached are introduced for different types of battery applications and the effects of these SSEs combined with MOFs on the electrochemical performance of the cells are described. Finally, some challenges faced by MOFs materials in batteries applications are presented, then some solutions to the problems and development expectations of MOFs are given.
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- 2023
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43. Toward a dynamic approach of person perception at zero acquaintance: Applying recurrence quantification analysis to thin slices
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Shu Jiang, Alexandra Paxton, Nairán Ramírez-Esparza, and Adrián García-Sierra
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Person perception ,Dynamical systems theory ,Thin-slice methodology ,Behavioral personality ,LENA ,Psychology ,BF1-990 - Abstract
Thin-slice methodology has provided us with abundant behavioral streams that self-reported measures would fail to capture, but traditional analytical paradigms in social and personality psychology cannot fully capture the temporal trajectories of person perception at zero acquaintance. At the same time, empirical investigations into how persons and situations jointly predict behavior enacted in situ are scarce, despite the importance of examining real-world behavior to understand any phenomenon of interest. To complement existing theoretical models and analyses, we propose the dynamic latent state-trait model blending dynamical systems theory and person perception. We present a data-driven case study using thin-slice methodology to demonstrate the model. This study provides direct empirical support for the proposed theoretical model on person perception at zero acquaintance highlighting the target, the perceiver, the situation, and time. The results of the study demonstrate that dynamical systems theory approaches can be leveraged to provide information about person perception at zero acquaintance above and beyond that of more traditional approaches. Classification code: 3040 (Social Perception & Cognition)
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- 2023
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44. Poetry in the Time of Pandemic: On My Favorite Novel Love in the Time of Cholera
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Lu, Shu-Jiang
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- 2021
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45. Vertical heterogeneity and the main controlling factors of the Upper Ordovician-Lower Silurian Wufeng-Longmaxi shales in the Middle Yangtze region
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Chuan Wang, Tian Dong, Shu Jiang, Yuying Zhang, Liuqing Yang, Xing Liang, and Gaocheng Wang
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wufeng-longmaxi shales ,heterogeneity ,shale lithofacies ,sedimentary paleoenvironment ,organic matter enrichment ,Geology ,QE1-996.5 ,Engineering geology. Rock mechanics. Soil mechanics. Underground construction ,TA703-712 - Abstract
The Upper Ordovician-Lower Silurian Wufeng-Longmaxi shales in the Middle Yangtze area have strong vertical heterogeneity, affecting the gas-bearing capacity of shale reservoirs and the fracturing ability.This study integrates wire-line logs, drilling cores, thin section observations, total organic carbon content, X-ray diffraction mineralogy measurement, and major, trace elements measurement.Under the stratigraphic sequence framework in the study area, the vertical variation of TOC content, mineralogical composition and shale lithofacies were studied.Combined with geochemical proxies for paleoclimate and paleoenvironmental conditions, the main factors controlling vertical heterogeneity were discussed.The results show that the Wufeng-Longmaxi shales have two 3rd-order sequences.The Wufeng Formation is divided into the transgressive systems tract(TST1) and high stand systems tract(HST), and the Longmaxi Formation is divided into the transgressive systems tract(TST2) and the early high stand systems tract(EHST).During the transgression period, the shale has high silica content, low clay content, and high organic carbon content, and mainly developed siliceous shale facies and clay-bearing siliceous shale facies.In the early high-stand systems tract period, shale developed silty bands and lenticular bedding, with high clay content, and low organic carbon content, and mainly developed siliceous-clay mixed shale lithofacies.The vertical changes of paleoclimate indicators(CIA, Rb/Sr), paleo-productivity indicators(Cu/Al, P/Al), redox environmental indicators(MoEF, UEF), and terrestrial input(Ti, Zr) indicators indicate a high productivity, anoxic sedimentary environment, low terrestrial input and relatively dry and cold climate conditions for the transgression period, while during the high-stand systems tract deposition, the study area has low productivity, oxic-dysoxic environment, high terrestrial input and relatively warm and humid climateconditions.The paleo climate, paleo productivity, redox conditions, volcanic activity, terrestrial input and bottom currents are the main factors controlling the stratigraphic heterogeneity of the Wufeng-Longmaxi shales in the study area.Finally, by comparing with some parameters of the shale in the Upper Yangtze region, it is found that the study area shows the differences in deeper burial depth, thinner organic shale, lower gas content and more brittle mineral content.
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- 2022
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46. Clinical outcomes in central nervous system solitary-fibrous tumor/hemangiopericytoma: a STROBE-compliant single-center analysis
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Yang Yu, Yu Hu, Liang Lv, Cheng Chen, Senlin Yin, Shu Jiang, and Peizhi Zhou
- Subjects
Solitary fibrous tumor ,Hemangiopericytoma ,Quality of life ,Prognosis ,Central nervous system ,Surgery ,RD1-811 ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Abstract Background Solitary fibrous tumor (SFT) and hemangiopericytoma (HPC) are rare mesenchymal tumors in the central nervous system with a high tendency to relapse, having a significant impact on quality of life (QoL). Due to the rarity of intracranial SFT/HPC, the prognostic factors and optimal treatment remain to be elucidated. Meanwhile, quality of life in patients with intracranial SFT/HPC is seldomly concerned. Thus, we aim to survey about the quality of life and underline some aspects demanding concern in intracranial SFT/HPC treatment through summarizing our case series in recent ten years. Methods Patients with intracranial SFT/HPC who underwent surgical resection from January 2009 to June 2019 were included in the study. Clinical features, such as age, gender, and resection extent, were collected. The EuroQol Five Dimensions Questionnaire (EQ-5D) was used to assess the patients’ quality of life (QoL). Prognosis factors related to progression-free survival (PFS) and overall survival (OS) were also evaluated. Results Thirty-six patients with a mean follow-up period of 61.6 months (range 13–123 months) were included in this study. Sixteen (44.4%) patients achieved gross total resection (GTR). Fourteen patients (38.9%) with tumor progression experienced adjuvant radiotherapy (11.1%) or Gamma Knife surgery (GKS, 27.8%). According to the 2016 WHO classification, there were 6 (16.7%) grade I SFT/HPC, 11 (30.5%) grade II SFT/HPC, and 19 (52.8%) grade III SFT/HPC. The PFS and OS were 29 months (range 4–96 months) and 38 months (range 4–125 months). The median EQ5D-3 L tariff with or without progression was 0.617 (95% CI 0.470–0.756) and 0.939 (95% CI 0.772–0.977) respectively. Gross total resection (GTR, p = 0.024) and grade I SFT/HPC (p = 0.017) were significantly associated with longer PFS. In multivariate analysis, GTR (HR 0.378, 95% CI 0.154–0.927) and adjuvant therapy (HR 0.336, 95% CI 0.118–0.956) result in significantly longer PFS in patients with SFT/HPC. Conclusions Patients underwent GTR and adjuvant therapy had longer PFS. Similarly, patients with lower WHO grade had relatively longer PFS. Therefore, GTR is advocated for the treatment of SFT/HPC. And adjuvant therapy such as GKS could be an alternative treatment for patients who underwent STR or with tumor progression. Further, the QoL decreased in patients with tumor progression and metastasis, and more attention is demanded to the QoL of intracranial SFT/HPC patients.
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- 2022
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47. A three dimensional visualized physical simulation for natural gas charging in the micro-nano pore system
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Juncheng QIAO, Jianhui ZENG, Yuxuan XIA, Jianchao CAI, Dongxia CHEN, Shu JIANG, Guomeng HAN, Zhe CAO, Xiao FENG, and Sen FENG
- Subjects
low permeability (tight) sandstone ,gas charging ,three-dimensional visualization ,physical simulation ,micro- nanometer pore network ,gas and water flow and distribution ,Petroleum refining. Petroleum products ,TP690-692.5 - Abstract
A micro-nano pore three-dimensional visualized real-time physical simulation of natural gas charging, in-situ pore-scale computation, pore network modelling, and apparent permeability evaluation theory were used to investigate laws of gas and water flow and their distribution, and controlling factors during the gas charging process in low-permeability (tight) sandstone reservoir. By describing features of gas-water flow and distribution and their variations in the micro-nano pore system, it is found that the gas charging in the low permeability (tight) sandstone can be divided into two stages, expansion stage and stable stage. In the expansion stage, the gas flows continuously first into large-sized pores then small-sized pores, and first into centers of the pores then edges of pores; pore-throats greater than 20 μm in radius make up the major pathway for gas charging. With the increase of charging pressure, movable water in the edges of large-sized pores and in the centers of small pores is displaced out successively. Pore-throats of 20–50 μm in radius and pore-throats less than 20 μm in radius dominate the expansion of gas charging channels at different stages of charging in turn, leading to reductions in pore-throat radius, throat length and coordination number of the pathway, which is the main increase stage of gas permeability and gas saturation. Among which, pore-throats 30–50 μm in radius control the increase pattern of gas saturation. In the stable stage, gas charging pathways have expanded to the maximum, so the pathways keep stable in pore-throat radius, throat length, and coordination number, and irreducible water remains in the pore system, the gas phase is in concentrated clusters, while the water phase is in the form of dispersed thin film, and the gas saturation and gas permeability tend stable. Connected pore-throats less than 20 μm in radius control the expansion limit of the charging pathways, the formation of stable gas-water distribution, and the maximum gas saturation. The heterogeneity of connected pore-throats affects the dynamic variations of gas phase charging and gas-water distribution. It can be concluded that the pore-throat configuration and heterogeneity of the micro-nanometer pore system control the dynamic variations of the low-permeability (tight) sandstone gas charging process and gas-water distribution features.
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- 2022
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48. Review on A big data-based innovative knowledge teaching evaluation system in universities
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Xin, Xu, Shu-Jiang, Yu, Nan, Pang, ChenXu, Dou, and Dan, Li
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- 2022
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49. Tri-training for Dependency Parsing Domain Adaptation.
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Shu Jiang, Zuchao Li, Hai Zhao 0001, Bao-Liang Lu, and Rui Wang 0015
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- 2022
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50. Bioactive graphene oxide-functionalized self-expandable hydrophilic and osteogenic nanocomposite for orthopaedic applications
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Quan-Chang Tan, Xia-Shu Jiang, Lei Chen, Jin-Feng Huang, Qiu-Xia Zhou, Jing Wang, Yan Zhao, Bo Zhang, Ya-Ni Sun, Min Wei, Xiong Zhao, Zhao Yang, Wei Lei, Yu-Fei Tang, and Zi-Xiang Wu
- Subjects
Expandable material ,Graphene oxide ,Water absorption ,Biomechanics ,Osteointegration ,Medicine (General) ,R5-920 ,Biology (General) ,QH301-705.5 - Abstract
Polymethyl methacrylate (PMMA) bone cement (PBC) is commonly used in orthopaedic surgery. However, polymerization volumetric shrinkage, exothermic injury, and low bioactivity prevent PBC from being an ideal material. The developed expandable P(MMA-AA-St) well overcomes the volumetric shrinkage of PBC. However, its biomechanical properties are unsatisfactory. Herein, graphene oxide (GO), a hydrophilic material with favourable biomechanics and osteogenic capability, was added to P(MMA-AA-St) to optimize its biomechanics and bioactivity. The GO-modified self-expandable P(MMA-AA-St)-GO nanocomposite (PGBCs) exhibited outstanding compressive strength (>70 MPa), water absorption, and volume expansion, as well as a longer handling time and a reduced setting temperature. The cytocompatibility of PGBCs was superior to that of PBC, as demonstrated by CCK-8 assay, live-dead cell staining, and flow cytometry. In addition, better osteoblast attachment was observed, which could be attributed to the effects of GO. The improved level of osteogenic gene and protein expression further illustrated the improved cell-material interactions between osteoblasts and PGBCs. The results of an in vivo study performed by filling bone defects in the femoral condyles of rabbits with PGBCs demonstrated promising intraoperative handling properties and convenient implantation. Blood testing and histological staining demonstrated satisfactory in vivo biosafety. Furthermore, bone morphological and microarchitecture analyses using bone tissue staining and micro-CT scanning revealed better bone-PGBCs contact and osteogenic capability. The results of this study indicate that GO modification improved the physiochemical properties, cytocompatibility, and osteogenic capability of P(MMA-AA-St) and overcame the drawbacks of PBC, allowing its material derivatives to serve as effective implantable biomaterials.
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- 2023
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