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1,894 results on '"Schmitt, Fernando"'

1. Standardization through education of molecular pathology: a spotlight on the European Masters in Molecular Pathology

Author

Ilié, Marius, Lake, Vivien, de Alava, Enrique, Bonin, Serena, Chlebowski, Sandra, Delort, Aurélie, Dequeker, Elisabeth, Al-Dieri, Raed, Diepstra, Arjan, Carpén, Olli, Eloy, Catarina, Fassina, Ambrogio, Fend, Falko, Fernandez, Pedro L., Gorkiewicz, Gregor, Heeke, Simon, Henrique, Rui, Hoefler, Gerald, Huertas, Pablo, Hummel, Michael, Kashofer, Karl, van der Laak, Jeroen, de Pablos, Rocio Martinez, Schmitt, Fernando, Schuuring, Ed, Stanta, Giorgio, Timens, Wim, Westphalen, Benedikt, and Hofman, Paul

Published
2024
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3. The current state of digital cytology and artificial intelligence (AI): global survey results from the American Society of Cytopathology Digital Cytology Task Force

Author

Kim, David, Thrall, Michael J., Michelow, Pamela, Schmitt, Fernando C., Vielh, Philippe R., Siddiqui, Momin T., Sundling, Kaitlin E., Virk, Renu, Alperstein, Susan, Bui, Marilyn M., Chen-Yost, Heather, Donnelly, Amber D., Lin, Oscar, Liu, Xiaoying, Madrigal, Emilio, Zakowski, Maureen F., Parwani, Anil V., Jenkins, Elizabeth, Pantanowitz, Liron, and Li, Zaibo

Published
2024
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5. Fibroadenoma

Author

Gudi, Mihir, Tse, Gary, Tan, Puay-Hoon, Schmitt, Fernando, Tse, Gary, editor, Tan, Puay-Hoon, editor, and Schmitt, Fernando, editor

Published
2023
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8. Aspiration Techniques

Author

Pinto, Daniel Gomes, Tse, Gary, Tan, Puay-Hoon, Schmitt, Fernando, Tse, Gary, editor, Tan, Puay-Hoon, editor, and Schmitt, Fernando, editor

Published
2023
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15. Future Directions

Author

Tse, Gary, Tan, Puay-Hoon, Schmitt, Fernando, Tse, Gary, editor, Tan, Puay-Hoon, editor, and Schmitt, Fernando, editor

Published
2023
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17. Mucinous Lesions

Author

Callé, Catarina, Schmitt, Fernando, Tse, Gary, Tan, Puay-Hoon, Tse, Gary, editor, Tan, Puay-Hoon, editor, and Schmitt, Fernando, editor

Published
2023
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18. Other Uncommon Lesions

Author

Ni, Yunbi, Tse, Gary, Tan, Puay-Hoon, Schmitt, Fernando, Tse, Gary, editor, Tan, Puay-Hoon, editor, and Schmitt, Fernando, editor

Published
2023
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20. Carcinoma and Variants

Author

Tse, Gary, Tan, Puay-Hoon, Schmitt, Fernando, Gudi, Mihir, Tse, Gary, editor, Tan, Puay-Hoon, editor, and Schmitt, Fernando, editor

Published
2023
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21. Assessment of Axillary Nodes

Author

Wong, Jill Su Lin, Ho, Gay Hui, Tse, Gary, Tan, Puay-Hoon, Schmitt, Fernando, Tse, Gary, editor, Tan, Puay-Hoon, editor, and Schmitt, Fernando, editor

Published
2023
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24. Digital cytology part 1: digital cytology implementation for practice: a concept paper with review and recommendations from the American Society of Cytopathology Digital Cytology Task Force

Author

Kim, David, Sundling, Kaitlin E., Virk, Renu, Thrall, Michael J., Alperstein, Susan, Bui, Marilyn M., Chen-Yost, Heather, Donnelly, Amber D., Lin, Oscar, Liu, Xiaoying, Madrigal, Emilio, Michelow, Pamela, Schmitt, Fernando C., Vielh, Philippe R., Zakowski, Maureen F., Parwani, Anil V., Jenkins, Elizabeth, Siddiqui, Momin T., Pantanowitz, Liron, and Li, Zaibo

Published
2024
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25. Digital cytology part 2: artificial intelligence in cytology: a concept paper with review and recommendations from the American Society of Cytopathology Digital Cytology Task Force

Author

Kim, David, Sundling, Kaitlin E., Virk, Renu, Thrall, Michael J., Alperstein, Susan, Bui, Marilyn M., Chen-Yost, Heather, Donnelly, Amber D., Lin, Oscar, Liu, Xiaoying, Madrigal, Emilio, Michelow, Pamela, Schmitt, Fernando C., Vielh, Philippe R., Zakowski, Maureen F., Parwani, Anil V., Jenkins, Elizabeth, Siddiqui, Momin T., Pantanowitz, Liron, and Li, Zaibo

Published
2024
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28. A brief review of the WHO reporting system for lung cytopathology

Author

Canberk, Sule, Field, Andrew, Bubendorf, Lukas, Chandra, Ashish, Cree, Ian A., Engels, Marianne, Hiroshima, Kenzo, Jain, Deepali, Kholová, Ivana, Layfield, Lester, Mehrotra, Ravi, Michael, Claire, Osamura, Robert, Pitman, Martha B., Roy-Chowdhuri, Sinchita, Satoh, Yukitoshi, VanderLaan, Paul, Zakowski, Maureen, and Schmitt, Fernando C.

Published
2023
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30. Reporting of Surgically Removed Lymph Nodes for Breast Tumors: Recommendations From the International Collaboration on Cancer Reporting

Author

Cserni, Gabor, Brogi, Edi, Cody, Hiram S., III, Deb, Rahul, Farshid, Gelareh, O'Toole, Sandra, Provenzano, Elena, Quinn, Cecily M., Sahin, Aysegul A., Schmitt, Fernando, Weaver, Donald L., Yamaguchi, Rin, Webster, Fleur, and Tan, Puay Hoon

Subjects
Clinical pathology -- Standards, Lymph nodes -- Surgery, Practice guidelines (Medicine), Lymphatic metastasis -- Diagnosis, Data entry -- Methods, Breast cancer -- Diagnosis, Health
Abstract

* Context.--The International Collaboration on Cancer Reporting (ICCR), supported by major pathology and cancer organizations, aims at the standardization of evidence-based pathology reporting of different types of cancers, with the inclusion of all parameters deemed to be relevant for best patient care and future data collection. Lymph node metastasis is one of the most important prognostic factors in breast cancer. Objective.--To produce a histopathology reporting guide by a panel of recognized experts from the fields of pathology and surgery with elements deemed to be core (required) and noncore (recommended) to report when assessing regional lymph nodes of patients with breast cancer. Data Sources.--Published literature, previous guidelines/recommendations, and current cancer staging principles were the basis of the data set drafted by the expert panel. This was discussed in a series of teleconferences and email communications. The draft data set was then made available for public consultation through the ICCR Web site. After this consultation and ICCR ratification, the data set was finalized. Conclusions.--The ICCR has published a data set for the reporting of surgically removed lymph nodes (including sentinel lymph node biopsy, axillary lymph node dissection, targeted axillary surgery, and lymph node sampling specimens) for breast tumors. This is part of a series of 4 ICCR breast cancer-related data sets. It includes 10 core elements along with 2 noncore elements. This should allow for synoptic reporting, which is more precise, uniform, and complete than nonsynoptic reporting, and leads to improved patient outcomes. doi: 10.5858/arpa.2022-0060-RA, The International Collaboration on Cancer Reporting (ICCR) stems from an unprecedented effort to provide standards for evidence-based reporting of the pathologic diagnosis of different types of cancers, including all parameters [...]

Published
2022
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31. Combination of Biochemical and Cytological Findings for Better Diagnosis in Pleural Effusions

Author

Elmas, Hatice, Biancosino, Christian, Önal, Binnur, Schmitt, Fernando, Buyucek, Seyma, Nordholt, Gerhard, Sauter, Guido, Welker, Lutz, Crusio, Wim E., Series Editor, Dong, Haidong, Series Editor, Radeke, Heinfried H., Series Editor, Rezaei, Nima, Series Editor, Steinlein, Ortrud, Series Editor, Xiao, Junjie, Series Editor, and Pokorski, Mieczyslaw, editor

Published
2022
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32. Ancillary Studies in Urinary Cytology

Author

Bubendorf, Lukas, Caraway, Nancy P., Fischer, Andrew H., Katz, Ruth L., Schmitt, Fernando, Fležar, Margareta Strojan, Van der Kwast, Theodorus H., Vielh, Philippe, Wojcik, Eva M., editor, Kurtycz, Daniel F.I., editor, and Rosenthal, Dorothy L., editor

Published
2022
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37. Suspicious of Malignancy

Author

Field, Andrew S., Sauer, Torill, Ljung, Britt-Marie, Lee, Andrew H. S., Raymond, Wendy A., Geddie, William R., Schmitt, Fernando, Field, Andrew S., editor, Raymond, Wendy A., editor, and Schmitt, Fernando, editor

Published
2020
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38. Insufficient/Inadequate

Author

Raymond, Wendy A., Field, Andrew S., Lee, Andrew H. S., Schmitt, Fernando, Field, Andrew S., editor, Raymond, Wendy A., editor, and Schmitt, Fernando, editor

Published
2020
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39. Malignant

Author

Brachtel, Elena F., Field, Andrew S., Rickard, Mary T., Raymond, Wendy A., Lee, Andrew H. S., Chong, P. Y., Chen, Lan, Chaiwun, Benjaporn, Arnold, Lauren, Geddie, William R., Schmitt, Fernando, Field, Andrew S., editor, Raymond, Wendy A., editor, and Schmitt, Fernando, editor

Published
2020
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40. The International Academy of Cytology Yokohama System for Reporting Breast Fine Needle Aspiration Biopsy Cytopathology: Introduction and Overview

Author

Field, Andrew S., Raymond, Wendy A., Rickard, Mary T., Arnold, Lauren, Brachtel, Elena F., Chaiwun, Benjaporn, Chen, Lan, Chong, P. Y., Di Bonito, Luigi, Hoda, Rana S., Kurtycz, Daniel F. I., Lee, Andrew H. S., Lim, Elgene, Ljung, Britt-Marie, Michelow, Pamela, Osamura, Robert Y., Pinamonti, Maurizio, Sauer, Torill, Segara, Davendra, Tse, Gary M., Vielh, Philippe, Schmitt, Fernando, Field, Andrew S., editor, Raymond, Wendy A., editor, and Schmitt, Fernando, editor

Published
2020
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41. Clinical Management

Author

Cohen-Hallaleh, Ruben, Rickard, Mary T., Lim, Elgene, Raymond, Wendy A., Segara, Davendra, Arnold, Lauren, Lee, Andrew H. S., Schmitt, Fernando, Field, Andrew S., Field, Andrew S., editor, Raymond, Wendy A., editor, and Schmitt, Fernando, editor

Published
2020
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42. Benign

Author

Field, Andrew S., Di Bonito, Luigi, Pinamonti, Maurizio, Michelow, Pamela, Raymond, Wendy A., Sauer, Torill, Lee, Andrew H. S., Rickard, Mary T., Arnold, Lauren, Geddie, William R., Schmitt, Fernando, Field, Andrew S., editor, Raymond, Wendy A., editor, and Schmitt, Fernando, editor

Published
2020
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44. Atypical

Author

Field, Andrew S., Ljung, Britt-Marie, Rickard, Mary T., Tse, Gary M., Sauer, Torill, Lee, Andrew H. S., Schmitt, Fernando, Geddie, William R., Raymond, Wendy A., Field, Andrew S., editor, Raymond, Wendy A., editor, and Schmitt, Fernando, editor

Published
2020
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47. Nerve growth factor inducible (VGF) is a secreted mediator for metastatic breast cancer tropism to the brain.

Author

Carvalho, Rita, Santos, Liliana, Conde, Inês, Leitão, Ricardo, Ferreira, Hugo RS, Gomes, Célia, Silva, Ana Paula, Schmitt, Fernando, Carvalho‐Maia, Carina, Lobo, João, Jerónimo, Carmen, Paredes, Joana, and Ribeiro, Ana Sofia

Subjects
METASTATIC breast cancer, EPIDERMAL growth factor receptors, NERVE growth factor, BRAIN metastasis, PROGNOSTIC models
Abstract

Brain metastases are one of the most serious clinical problems in breast cancer (BC) progression, associated with lower survival rates and a lack of effective therapies. Thus, to dissect the early stages of the brain metastatic process, we studied the impact of brain organotropic BC cells' secretomes on the establishment of the brain pre‐metastatic niche (PMN). We found that BC cells with specific tropism to the brain caused significant blood–brain barrier (BBB) disruption, as well as microglial activation, in both in vitro and in vivo models. Further, we searched for a brain‐organotropic metastatic signature, as a promising source for the discovery of new biomarkers involved in brain metastatic progression. Of relevance, we identified VGF (nerve growth factor inducible) as a key mediator in this process, also impacting the BBB and microglial functions both in vitro and in vivo. In a series of human breast tumors, VGF was found to be expressed in both cancer cells and the adjacent stroma. Importantly, VGF‐positive tumors showed a significantly worse prognosis and were associated with HER2 (human epidermal growth factor receptor 2) overexpression and triple‐negative molecular signatures. Further clinical validation in primary tumors from metastatic BC cases showed a significant association between VGF and the brain metastatic location, clearly and significantly impacting on the prognosis of BC patients with brain metastasis. In conclusion, our study reveals a unique secretome signature for BC with a tropism for the brain, highlighting VGF as a crucial mediator in this process. Furthermore, its specific impact as a poor prognostic predictor for BC patients with brain metastasis opens new avenues to target VGF to control the progression of brain metastatic disease. © 2024 The Pathological Society of Great Britain and Ireland. [ABSTRACT FROM AUTHOR]

Published
2024
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