41 results on '"Schlesinger, David J"'
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2. Leksell Gamma Knife Radiosurgery
- Author
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Dayawansa, Sam, Cordeiro, Diogo P., Schlesinger, David J., Trifiletti, Daniel M., editor, Chao, Samuel T., editor, Sahgal, Arjun, editor, and Sheehan, Jason P., editor
- Published
- 2024
- Full Text
- View/download PDF
3. Physics and Radiobiology
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Trifiletti, Daniel M., Zaorsky, Nicholas G., Schlesinger, David J., Trifiletti, Daniel M., editor, and Zaorsky, Nicholas G., editor
- Published
- 2019
- Full Text
- View/download PDF
4. Leksell Gamma Knife Radiosurgery
- Author
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Cordeiro, Diogo P., Schlesinger, David J., Trifiletti, Daniel M., editor, Chao, Samuel T., editor, Sahgal, Arjun, editor, and Sheehan, Jason P., editor
- Published
- 2019
- Full Text
- View/download PDF
5. Physics of Radiosurgery
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Lee, Yongsook C., Goetsch, Steven J., Schlesinger, David J., Benedict, Stanley H., Trifiletti, Daniel M., editor, Chao, Samuel T., editor, Sahgal, Arjun, editor, and Sheehan, Jason P., editor
- Published
- 2019
- Full Text
- View/download PDF
6. Safety and feasibility of STAT RAD: Improvement of a novel rapid tomotherapy-based radiation therapy workflow by failure mode and effects analysis
- Author
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Jones, Ryan T., Handsfield, Lydia, Read, Paul W., Wilson, David D., Van Ausdal, Ray, Schlesinger, David J., Siebers, Jeffrey V., and Chen, Quan
- Published
- 2015
- Full Text
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7. 293 - Radiosurgery Technique
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Trifiletti, Daniel M., Lee, Cheng-Chia, Schlesinger, David J., and Sheehan, Jason P.
- Published
- 2023
- Full Text
- View/download PDF
8. 8+ Year Performance of the Gamma Knife Perfexion/Icon Patient Positioning System and Possibilities for Preemptive Fault Detection Using Statistical Process Control
- Author
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Schlesinger, David J., primary, Sanders, Jason C., additional, Muller, Donald A., additional, Nordström, Håkan, additional, and Sheehan, Jason P., additional
- Published
- 2021
- Full Text
- View/download PDF
9. Gamma knife radiosurgery for brain metastasis of nonsmall cell lung cancer: Is there a difference in outcome between morning and afternoon treatment?
- Author
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Rahn, Douglas A., III, Ray, Dibyendu K., Schlesinger, David J., Steiner, Ladislau, Sheehan, Jason P., OʼQuigley, John M., and Rich, Tyvin
- Published
- 2011
- Full Text
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10. Advanced group treament for developmentally disabled adults with social skill deficits
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Hall, James A., Dineen, John P., Schlesinger, David J., and Stanton, Roger
- Subjects
Developmentally disabled -- Care and treatment ,Social skills -- Study and teaching ,Sociology and social work - Abstract
Developmentally disabled adults can be taught social skills in a group setting, although the program used for this study showed mixed results. Posttreatment followup 1 year later showed maintenance for most skills.
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- 2000
11. Survey on human papillomavirus/p16 screening use in oropharyngeal carcinoma patients in the United States
- Author
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Shoushtari, Asal N., Rahimi, Nina P., Schlesinger, David J., and Read, Paul W.
- Published
- 2010
- Full Text
- View/download PDF
12. Contributors
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Aarabi, Bizhan, Abbott, Rick, Abd-El-Barr, Muhammad M., Abel, Taylor J., Abou-Al-Shaar, Hussam, Acar, Feridun, Achey, Rebecca L., Ackerman, Laurie L., Adappa, Nithin D., Adelson, P. David, Agarwal, Nitin, Aguirre-Padilla, David H., Ahluwalia, Manmeet S., Ahmad, Shahjehan, Ahmed, A. Karim, Ahmed, Raheel, Aisiku, Imoigele P., Akbar, Muhammad A., Akram, Harith, Alaraj, Ali, Albrecht, Jennifer S., Albuquerque, Felipe C., Alexander, Michael J., Alexandrov, Andrei V., Alexopoulos, Andreas V., Ali, Zarina S., Al-Khalili, Kenan, Al-Mefty, Ossama, Al-Mefty, Rami O., Alnahhas, Iyad, Alrobaian, Malek, Al-Saiegh, Fadi, Alterman, Ron L., Altshuler, David B., Amenta, Peter S., Ames, Christopher P., Amin-Hanjani, Sepideh, Ammirati, Mario, Andaluz, Norberto, Anderson, Richard C.E., Andrade, Pablo, Ares, William J., Arle, Jeffrey E., Arnaout, Omar, Arnold, Paul M., Assina, Rachid, Aszmann, Oskar C., Attenello, Frank J., III, Attia, Albert, Avellino, Anthony M., Awad, Issam A., Ayantayo, Temitayo O., Bader, Edward R., Badhiwala, Jetan H., Baehring, Joachim M., Bagic´, Anto I., Bagley, Stephen J., Bai, Michael Y., Bailes, Julian E., Bain, Mark, Baker, Turner, Ball, Perry A., Ballester, Leomar Y., Balu, Ramani, Ban, Vin Shen, Barak, Tanyeri, Baranoski, Jacob F., Barbaro, Nicholas M., Barber, Sean M., Barker, Frederick G., II, Barnett, Gene H., Barone, Constance M., Barrow, Daniel Louis, Basma, Jaafar, Batchelor, Tracy T., Batjer, H. Hunt, Beattie, Michael S., Beaumont, Andrew, Beaumont, Thomas L., Bederson, Joshua B., Belani, Puneet, Belzberg, Allan J., Benet, Arnau, Ben-Haim, Sharona, Berenstein, Alejandro, Berga, Sarah L., Berger, Mitchel S., Bergsneider, Marvin, Bernstock, Joshua D., Bhatia, Sanjay, Bi, Wenya Linda, Bigder, Mark G., Bijlenga, Philippe, Bingaman, William, Birk, Harjus S., Bishop, Allen T., Blakeley, Jaishri O., Blomstedt, Patric, Blue, Rachel, Blumenthal, Scott, Boaro, Alessandro, Boddu, James V., Bohnen, Angela, Bok, Arnold P., Boone, Myles D., Boop, Frederick A., Boszczyk, Bronek M., Bowyer, Susan M., Brahimaj, Bledi C., Brem, Henry, Brem, Steven, Bresnahan, Jacqueline C., Brinjikji, Waleed, Brinkmann, Benjamin H., Brînzeu, Andrei, Britz, Gavin W., Brockmeyer, Douglas L., Brown, Desmond A., Brown, Justin M., Brown, Matthew T., Brown, Robert D., Jr., Bruce, Jeffrey N., Bruckman, Karl C., Bruhat, Alexis, Brunstrom-Hernandez, Janice E., Brunswick, Andrew, Bruzek, Amy K., Buchanan, Ian A., Budohoski, Karol P., Buell, Thomas J., Büki, András, Bunevicius, Adomas, Burchiel, Kim J., Bydon, Mohamad, Byrne, Richard W., Cabrejo, Raysa, Cabrilo, Ivan, Cahill, Daniel P., Caplan, Justin M., Carlson, Andrew P., Carrión-Penagos, Julián, Carroll, Benjamin W., Cascino, Gregory D., Castaneyra-Ruiz, Leandro, Castinetti, Frederic, Cavalcanti, Daniel D., Cawley, C. Michael, Cernak, Ibolja, Cetas, Justin S., Chan, Michael D., Ka-Ying Chan, Vivien, Chang, Chih-Chang, Chang, Louis, Chang, Steven D., Charbel, Fady T., Charest-Morin, Raphaële, Chari, Aswin, Chaudhary, Navjot, Chauvel, Patrick, Chen, Kevin S., Chen, Liang, Cheng, Joseph, Cherian, Jacob, Cheung, Kenneth M.C., Cheyuo, Cletus, Chiang, Veronica L., Chiarelli, Peter A., Chiocca, E. Antonio, Chitale, Rohan V., Cho, Catherine, Choi, Heejung, Chou, Dean, Christian, Cindy W., Christiansen, Peter A., Church, Ephraim W., Clarke, Jennifer L., Cleary, Daniel R., Clune, James E., Cohen, Justin D., Cohen-Inbar, Or, Colasanti, Roberto, Collins, John M., Comair, Youssef G., Conner, Andrew K.P., Connolly, E. Sander, Jr., Cooper, Jared B., Corcos, Daniel Montie, Coric, Domagoj, Costa, Anthony B., Couldwell, William T., Crino, Peter B., Crofton, Andrew R., Cullen, D. Kacy, Curt, Armin, Dacey, Ralph G., Jr., Daci, Rrita, Dailey, Andrew T., D’Alessandris, Quintino Giorgio, Damisah, Eyiyemisi C., Daniels, David J., Das, Sunit, Davanzo, Justin R., David, Carlos A., David, David J., Davidson, Benjamin, Davis, Gavin A., Day, Arthur L., Dea, Nicolas, De Donato, Giuseppe, Deiner, Stacie, De la Garza, Carlos, Delavari, Nader, Del Brutto, Oscar H., Delman, Bradley N., DeLong, Mahlon R., DeMonte, Franco, de Oliveira, Evandro, Derman, Peter B., Desai, Arati, Deshpande, Krutika, Diaz, Michele, Diaz-Arrastia, Ramon R., DiGiorgio, Anthony M., DiLuna, Michael L., DiMeco, Francesco, Dlouhy, Brian J., Doğruel, Yücel, Donahue, Joseph H., Donoho, Daniel A., Doshi, Amish H., Dreier, Jens P., Driver, Joseph, Drofa, Alexander, Ducruet, Andrew F., Duffau, Hugues, Duhaime, Ann-Christine, Dumont, Aaron S., Duncan, John S., Dunn, Gavin P., Dunn, Ian F., Eberwine, James H., Eckardt, Gerald W., Edem, Idara J., Edwards, Michael S.B., Egemen, Emrah, Eisenbarth, Rachel, Eisenberg, Howard, Elder, J. Bradley, Elhammady, Mohamed Samy, Elias, W. Jeffrey, Ellingson, Benjamin M., Ellis, Jason A., Elswick, Clay M., Emch, Todd M., Emerson, Samuel, Ene, Chibawanye I., Englot, Dario J., Erdman, John H., III, Eskandari, Ramin, Essayed, Walid Ibn, Everson, Richard G., Fadul, Camilo E., Fan, Yi, Farina, Dario, Farrell, Christopher J., Feghali, James, Fehlings, Michael G., Fehnel, Katie Pricola, Feigin, Valery L., Feldman, Eva L., Feldman, Michael J., Feldstein, Neil, Fenno, Lief E., Ferguson, Adam R., Feroze, Abdullah H., Fessler, Richard G., Filler, Aaron G., Findlay, J. Max, Finn, Michael A., Finnell, Richard H., Fisher, Charles G., Flamm, Eugene S., Flanders, Tracy M., Flemming, Kelly D., Flores-Sarnat, Laura, Follett, Kenneth A., Fontes, Ricardo B.V., Ford, Paul J., Foreman, Brandon P., Foreman, Paul M., Fornoff, Linden E., Fouda, Mohammed A., Foyouzi, Nastaran, Franco, Daniel, Franzini, Andrea, Fridley, Jared S., Friedlander, Robert M., Frisoli, Fabio A., Fry, Donald E., Gregory Fu, Kai-Ming, Fujita, Naohide, Fulbright, Robert K., Fulkerson, Daniel H., Fuller, Gregory N., Fusco, Matthew R., Galanopoulou, Aristea S., Gallagher, Gary W., Galvan, Adriana, Gander, Phillip E., Gandhi, Chirag D., Gao, Guoyi, Garcia, Hector H., García, Paul S., Gardner, Paul A., Gardner, Raquel C., Garzon-Muvdi, Tomas, Gavin, Cormac G., Gea-Banacloche, Juan C., George, Timothy M., Georgoulis, George D., Gerard, Carter S., Gerety, Patrick A., Gerszten, Kristina, Gerszten, Peter C., Ghaith, Abdul Karim, Ghatan, Saadi, Ghobrial, George M., Ghogawala, Zoher, Ghosh, Chaitali, Giacino, Joseph T., Giacobbe, Peter, Gianaris, Thomas J., Giannotta, Steven L., Giglio, Pierre, Gilad, Ronit, Gill, Brian J.A., Gillick, John L., Gilmer, Holly S., Gjedde, Albert H., Glenn, Chad A., Godil, Saniya S., Goel, Atul, Gokaslan, Ziya L., Goldberg, Jacob L., Goldstein, Hannah E., Golub, Danielle, Gonzalez, Glenn A., Gonzalez-Martinez, Jorge Á., Goodden, John R., Goodman, J. Clay, Goodrich, James Tait, Goodwin, C. Rory, Gordon, David S., Gottfried, Oren N., Goumnerova, Liliana C., Goyal, Anshit, Grady, M. Sean, Graffeo, Christopher S., Grafman, Jordan H., Gragnaniello, Cristian, Grande, Andrew W., Grant, Gerald A., Grebenciucova, Elena, Greenfield, Jeffrey, Grimaudo, Heather C., Groff, Michael W., Gross, Robert E., Grossman, Rachel, Groves, Mari L., Gstoettner, Clemens, Guenette, Jeffrey P., Günel, Murat, Gupta, Nalin, Gutman, Matthew J., Guyer, Richard D., Hachem, Laureen D., Haddad, Georges F., Hadjipanayis, Constantinos G., Hafez, Daniel M., Hagan, John P., Haglund, Michael M., Haines, Stephen J., Haldeman, Clayton L., Halvorson, Kyle G., Hamberger, Marla J., Hamdi, Hussein, Hamilton, D. Kojo, Hamilton, Kimberly M., Hamilton, Mark G., Hankinson, Todd C., Haq, Ihtsham ul, Harbaugh, Robert E., Hardesty, Douglas A., Hardigan, Trevor, Hariz, Marwan, Harrigan, Mark R., Harrop, James S., Hartings, Jed A., Härtl, Roger, Harward, Stephen C., II, Hasbun, Rodrigo, Hawryluk, Gregory W.J., Hayman, Erik, Hayward, Richard D., He, Lucy, Healy, Andrew T., Heary, Robert F., Heiden, Petra, Heinricher, Mary M., Heller, Robert S., Retel Helmrich, Isabel R.A., Helmy, Adel, Heman-Ackah, Sabrina M., Hendricks, Benjamin K., Herendeen, John S., Heros, Roberto C., Herrup, Karl, Hervey-Jumper, Shawn L., Heuer, Gregory G., Heyer, Eric J., Higuchi, Yoshinori, Hillary, Frank G., Ho, Winson S., Hoang, Nguyen, Hoang, Stanley, Hoelscher, Christian, Hoffer, S. Alan, Hofstetter, Christoph, Holland, Eric C., Holland, Ryan M., Holste, Katherine, Hongo, Kazuhiro, Horisawa, Shiro, Horner, Philip J., Howard, Matthew A., III, Hsueh, Brian, Huang, Judy, Huang, Kevin T., Huang, Michael C., Huang, Raymond Y., Hudgins, Eric, Huguenard, Anna, Hunt, Matthew A., Hurlbert, R. John, Hussein, Ahmed E., Hutchinson, Peter J., Huttner, Anita, Huys, Daniel, Hwang, Steven W., Iaccarino, Mary A., Ibrahim, Mohab, Iliff, Jeffrey J., Ilyas, Adeel, Ingram, Susan L., Isaacs, Albert M., Isaias, Ioannis U., Iskandar, Bermans J., Iyer, Aditya K., Jabbour, Pascal, Jackson, Christopher M., Jadhav, Ashutosh P., Jakobs, Martin, Jallo, George I., Jane, John A., Jr., Janigro, Damir, Jankowitz, Brian T., Jea, Andrew, Jehi, Lara, Jellinger, Kurt A., Jenson, Amanda V., Jho, Diana, Jiang, Bowen, Jiang, Fan, Jimenez, David F., Jimenez, Lincoln, Jin, Haiyan, Jo, Jasmin T., Johanson, Conrad E., Johnson, Luke A., Johnson, Mark D., Johnson, Nathaniel, Jones, Adrian C., Jones, Kristen E., Jones, Tuckerman, Joseph, Jacob R., Joshi, Krishna C., Joshi, Rushikesh S., Jovin, Tudor G., Julian, Alex, Juraschka, Kyle, Abdo do Seixo Kadri, Paulo, Kalani, M. Yashar S., Kalanithi, Paul S.A., Kalfas, Iain H., Kalnins, Aleksandrs Uldis, Kamath, Ashwin A., Kanev, Paul M., Kang, Daniel G., Kang, James D., Kanter, Adam S., Kaplitt, Michael G., Kappel, Ari D., Karikari, Isaac, Karsy, Michael, Kasliwal, Manish K., Kaufmann, Anthony M., Kawasaki, Hiroto, Kellner, Christopher P., Kelly, Alexander P., Kemeny, Andras A., Kestle, John R.W., Khalsa, Siri S., Khan, Imad S., Khan, Nadia, Khan, Tariq, Khanna, Omaditya, Khanna, Ryan, Kigerl, Kristina A., Kim, Dong H., Kim, Louis J., Kim, Paul K., Kim, Thomas A., Kim, Won, Kirnaz, Sertaç, Kirsch, Wolff, Kitchen, Neil D., Klein, Joshua P., Kliot, Michel, Knightly, John J., Knisely, Jonathan, Knopman, Jared, Ko, Andrew L., Kobayashi, Katsuya, Kobets, Andrew J., Koch, Matthew J., Kocharian, Gary, Koerner, John D., Kohara, Kotaro, Kohn, Max, Kolias, Angelos G., Koo, Clara S., Kosztowski, Thomas, Kotecha, Rupesh R., Kovach, Christopher K., Kraemer, Mark R., Krauss, Joachim K., Krieg, Sandro M., Krieger, Mark D., Krishnaney, Ajit A., Ksendzovsky, Alexander, Kulkarni, Abhaya V., Vijay Kumar, Gomatam R., Kumar, Sachin A., Kung, David K., Kuo, Jeffrey V., Kvint, Svetlana, Kwan, Kenny, Issa Laack, Nadia N., Ladner, Travis R., Lafage, Renaud, Lafage, Virginie, Lam, Arthur M., Lamm, Adam G., Landazuri, Patrick, Lanzino, Giuseppe, Larson, Paul, Lau, Catherine Y., Lau, Darryl, Lavine, Sean D., Lawler, Sean E., Laws, Edward R., Jr., Lawton, Michael T., Laxpati, Nealen G., Lebed, Brett D., Lee, Cheng-Chia, Lee, Jonathan J., Lee, Ryan P., Lee, Sangmi, Lehman, Ronald A., Jr., Lenke, Lawrence G., Le Roux, Peter D., Leuthardt, Eric C., Levin, Emily, Levy, Elad I., Lewis, Evan M., Lhatoo, Samden, Li, Dianyou, Li, Yingda, Ching Ng, Angela Li, Liau, Linda M., Liebenow, Brittany, Lieberman, Isador H., Limbrick, David D., Jr., Lin, Emily, Lin, Kant Y., Lin, Zhengyu, Lingsma, Hester F., Linskey, Mark E., Lipsman, Nir, Litvack, Zachary N., Liu, James K.C., Liu, Kenneth C., Liu, Wei, Lober, Robert M., Lohkamp, Laura-Nanna, Lonser, Russell R., Louvi, Angeliki, Lozano, Andres M., Lu, Victor M., Luciano, Mark G., Lukas, Rimas V., Luo, Lan, Ma, Lijun, Maas, Andrew I.R., Macdonald, R. Loch, Mack, William J., Mackey, Kimberly A., Macki, Mohamed, MacLachlan, Lara S., Madarash, Holly Oemke, Madsen, Peter J., Maegele, Marc, Magistretti, Pierre J., Mahan, Mark A., Maher, Cormac O., Mahtabfar, Aria, Majeed, Kashif, Makarenko, Serge, Makley, Amy T., Malessy, Martijn J.A., Malik, Athar N., Mallucci, Conor, Mambelli, Dorian D., Mammi, Marco, Mangano, Francesco T., Maniker, Allen H., Manley, Geoffrey T., Manolidis, Spiros, Maroon, Joseph C., Martin, Alastair, Martin, Neil A., Martirosian, Vahan, Martirosyan, Nikolay L., Maslink, Colin, Massie, Lara, Mathur, Amit M., Matias, Caio M., Mauer, Kimberly M., Maulucci, Christopher M., Maurer, Robert K., Mazur, Marcus D., Mazwi, Nicole, McAllister, James P., II, McClain, Craig D., McCormack, Ryan M., McCrea, Michael A., McCutcheon, Ian E., McDermott, Michael W., McDougall, Cameron G., McDougall, Cameron M., McEvoy, Andrew W., McGrath, Hari, McGrath, Lynn, Jr., McKhann, Guy M., McMahon, J. Tanner, McPheeters, Matthew J., Meaney, David F., Medel, Ricky, Medress, Zachary, Mehta, Minesh P., Menacho, Sarah T., Menezes, Arnold H., Menon, David K., Mergeche, Joanna L., Meyer, Fredric B., Meyer, Jenna, Meyer, Scott A., Meyers, Philip M., Midha, Rajiv, Miller, Charles A., Miller, Jonathan P., Miller, Neil R., Mirza, Farhan A., Mirzadeh, Zaman, Miserocchi, Anna, Misra, Basant K., Missios, Symeon, Miyagishima, Danielle F., Miyashiro, Kevin Y., Mizuno, Junichi, Mizuno, Shuichi, Mocco, J., Mohyeldin, Ahmed, Mokin, Maxim, Molinaro, Annette M., Moliterno, Jennifer, Monteith, Stephen J., Montenegro, Thiago S., Mooney, Michael A., Moosa, Shayan, Morales, Diego M., Morgan, Clinton D., Morgan, Isabella, Morgan, Michael Kerin, Mortimer, Vance R., Moss, Nelson, Moss, S. David, Mukherjee, Pratik, Mummaneni, Praveen V., Munich, Stephan A., Muraszko, Karin, Murthy, Saikiran G., Mushlin, Harry, Mussi, Antônio C.M., Nagel, Sean J., Nagy, Gábor, Nair, Dileep R., Najm, Imad M., Nakaji, Peter, Nakajima, Takeshi, Nasser, Rani, Nater, Anick, Navarro, Jovany Cruz, Nayak, Lakshmi, Neira, Justin A., Nelson, Lindsay D., Neman, Josh, Newell, David W., Nguyen, James H., Ngwenya, Laura Benjamin, Nicolato, Antonio, Nimjee, Shahid M., Nishimura, Sayoko, Niu, Tianyi, Norris, Scott A., Noureldine, Mohammad Hassan A., Nurmikko, Turo J., Nuwer, Marc R., Oberheim-Bush, Nancy Ann, Ochiai, Taku, Oh, Nathan, Oh, Taemin, Okonkwo, David O., Okun, Michael S., Oldfield, Edward H., Brigid O’Leary, Joanna Shawn, Olivi, Alessandro, O’Neill, Francis, Oppenlander, Mark E., Osbun, Joshua W., O’Toole, John E., Özduman, Koray, Ozpinar, Alp, Pain, Margaret, Palacios, Eva M., Palmer, James N., Pamir, M. Necmettin, Pamoukian, Vicken, Panesar, Sandip S., Panov, Fedor E., Paramasivam, Srinivasan, Park, Christine, Park, Jon, Park, Paul, Park, T.S., Parker, Whitney E., Parsa, Andrew T., Partington, Michael D., Patel, Aman B., Patel, Bhuvic, Patel, Smruti K., Patel, Vaibhav M., Patil, Parag G., Payne, Russell, Peeters, Sophie M., Pekmezci, Melike, Pendharkar, Arjun V., Penn, Richard Deren, Pennicooke, Brenton H., Pennington, Zach, Della Pepa, Giuseppe Maria, Perin, Alessandro, Perlmutter, Joel S., Persing, J. Scott, Persing, John A., Persing, Sarah M., Peters, Matthew E., Petersen, Erika A., Petrov, Dmitriy, Pham, Martin, Picht, Thomas, Piepmeier, Joseph M., Pikis, Stylianos, Pilcher, Webster H., Pinckard-Dover, Heather N., Pineda, José A., Pinter, Joseph D., Pisculli, Mary L., Pittman, Thomas, Plesnila, Nikolaus, Pollack, Ian F., Pollock, Bruce E., Polly, David W., Jr., Polster, Sean P., Popovich, Phillip G., Post, Kalmon D., Potts, Matthew B., Pouratian, Nader, Powers, Alexander K., Prager, Briana C., Prashant, Giyarpuram N., Prestigiacomo, Charles J., Prevedello, Daniel M., Proctor, Mark R., Prolo, Laura M., Prost, Robert W., Puduvalli, Vinay K., Purger, David A., Qualmann, Krista J., Quiñones-Hinojosa, Alfredo, Raffa, Scott J., Raghavan, Prashant, Rahal, Jason Pierce, Rajappa, Prajwal, Ram, Zvi, Ranjan, Manish, Rao, Ganesh, M.S. Raper, Daniel, Rapoport, Benjamin I., Raskin, Jeffrey S., Raslan, Ahmed M., Rasmussen, Peter, Rasouli, Jonathan J., Ravindra, Vijay M., Ray, Dibyendu K., Ray, Wilson Z., Raz, Eytan, Raza, Shaan M., Régis, Jean, Reilly, Peter L., Reith, Florence C.M., Rennert, Robert C., Resnick, Daniel K., Reynolds, Renée, Rezai, Ali R., Rhines, Laurence D., Rhoton, Albert L., Jr., Ribalta, Teresa, Richardson, R. Mark, Riggins, Gregory J., Riina, Howard A., Rinaldo, Lorenzo, Rincon-Torroella, Jordina, Ringer, Andrew J., Riva-Cambrin, Jay, Rizk, Elias, Robert, Stephanie M., Robertson, Claudia, Robertson, Jon H., Robinson, Leslie C., Robinson, Michael W., Robinson, Shenandoah, Roche, Aidan D., Roche, Pierre-Hugues, Rogg, Jeffrey M., Roguski, Marie, Roland, Jarod L., Rolston, John D., Rosenberg, William S., Rosenow, Joshua M., Rosenthal, Guy, Rosenwasser, Robert H., Roser, Florian, Rosner, Michael K., Rosseau, Gail, Rossi, Vincent J., Rovner, Eric S., Rubiano, Andres M., Rubio, Roberto Rodriguez, Rucker, Janet C., Rui, Yanning, Russin, Jonathan J., Rutka, James T., Saadeh, Yamaan S., Saatian, Behnaz, Sack, Kenneth D., Sader, Nicholas, Safaee, Michael M., Safain, Mina G., Sagher, Oren, Sahgal, Arjun, Saigal, Rajiv, Saito, Nobuhito, Saleh, Mohamed, Salinas, Ryan D., Salminger, Stefan, Samarage, H. Milan, Samdani, Amer F., Sand, Lauren A., Sani, Sepehr, Sankaran, Sujatha, Sansur, Charles A., Santarius, Thomas, Santiago, Paul, Santiago-Dieppa, David R., Santiago-Sim, Teresa, Sarkiss, Christopher A., Sarnat, Harvey B., Sarris, Christina E., Sather, Michael, Savastano, Luis E., Sawaya, Raymond, Schaller, Karl, Schiff, Nicholas D., Schipmann, Stephanie, Schlachter, Leslie, Schlesinger, David J., Schmidt, Franziska A., Schmidt, Meic H., Schneider, Lonnie, Schramm, Johannes, Schuele, Stephan U., Schulder, Michael, Schupper, Alexander J., Schwab, Frank J., Schwartz, Theodore H., Sciubba, Daniel M., Scott, R. Michael, Scullen, Tyler A., Selden, Nathan R., Sellin, Jonathan N., Selman, Warren R., Sen, Chandranath, Serizawa, Toru, Serrone, Joseph C., Sgubin, Donatella, Shaffrey, Christopher I., Shah, Kushal J., Shah, Lubdha M., Shah, Manish N., Shahlaie, Kiarash, Shapiro, Maksim, Sharan, Ashwini, Sharma, Deepak, Sharma, Mohan R., Sheehan, Jason P., Sheehan, Jonas M., Sheikhi, Lila, Shiflett, James M., Shigamatsu, Tomoyoshi, Shilpakar, Sushil Krishna, Shils, Jay L., Shimony, Nir, Shin, Alexander Y., Siddiqui, Adnan H., Sidhu, Meneka K., Silveira, Luke A., Silver, Jerry, Sindou, Marc, Singh, Jeffrey M., Singh, Manish K., Sizdahkhani, Saman, Skirboll, Stephen, Slavin, Justin, Smith, Brandon W., Smith, Edward R., Smith, Justin S., Smith, Kris A., Smith, Luke G.F., Smith, Timothy R., Smith, Yoland, Solomon, David A., Solomon, Robert A., Soltys, Scott G., Somji, Mohamed, Sorenson, Jeffrey M., Soriano, Sulpicio G., Sorscher, Michelle, Souweidane, Mark M., Spencer, Dennis D., Spetzler, Robert F., Spinazzi, Eleonora F., Spinner, Robert J., Sribnick, Eric A., Srinivasan, Visish M., Stabingas, Kristen, Stapleton, Christopher J., Starke, Robert M., Starr, Philip, St. Clair, Eric G., Stedelin, Brittany, Stefko, S. Tonya, Steinberg, Gary K., Stern, Matthew A., Steyerberg, Ewout W., Stieg, Philip E., Stone, Scellig S.D., Stoodley, Marcus, Strahle, Jennifer M., Stricsek, Geoffrey, Strong, Anthony, Strowd, Roy E., III, Stummer, Walter, Su, YouRong S., Sughrue, Michael E., Suh, John H., Sulaiman, Wale A.R., Sun, Bomin, Sun, Matthew Z., Sun, Xiaonan Richard, Sundaram, Vikram K., Sweid, Ahmad, Syed, Hasan R., Tagliati, Michele, Taira, Takaomi, Tajsic, Tamara, Takagi, Yasushi, Takeoka, Yoshiki, Tamargo, Rafael J., Tanaka, Shota, Tandon, Nitin, Tang, Daniel D., Tanweer, Omar, Tate, Matthew C., Tatsui, Claudio E., Taylor, Jennie W., Taylor, Jesse A., Taylor, Michael D., Templer, Jessica W., Teo, Charles, Tessier, Jeffrey M., Theadom, Alice, Theodore, Nicholas, Thinwa, Josephine W., Thompson, B. Gregory, Jr., Thompson, Eric M., Thompson, Stephen A., Thon, Niklas, Thurtell, Matthew J., Tilton, Ann H., Timmons, Shelly D., Tonn, Jörg-Christian, Toth, Gabor, Toussaint, Charles P., Tran, Minh H., Trapp, Bruce D., Traylor, Jeffrey I., Trifiletti, Daniel M., Tse, Kai-Hei, Tubbs, R. Shane, Tuleasca, Constantin, Tunkel, Allan R., Türe, Ugur, Umansky, Daniel, Unda, Santiago R., Ung, Timothy H., Upadhyayula, Pavan S., Uribe, Juan S., Uy, Benjamin R., Vaccaro, Alexander R., Vakharia, Kunal, Vakharia, Vejay N., Valvassori, Luca, van den Bent, Martin J., Van Gompel, Jamie J., Vasquez, Carlos M., Vasudeva, Viren S., Vasudevan, Kumar, Vellimana, Ananth K., Verlicchi, Angela, Vervoordt, Samantha M., Viapiano, Mariano S., Vide, Sérgio, Villa, Genaro R., Virk, Michael S., Visser-Vandewalle, Veerle, Vitek, Jerrold L., Vivas-Buitrago, Tito, Vo, Chau D., Vogelbaum, Michael A., Vollmer, Dennis G., Wackym, P. Ashley, Wainwright, Mark S., Wali, Arvin R., Walker, Corey T., Walters, Beverly C., Wang, Anthony C., Wang, Arthur, Wang, Huan, Wang, Joshua L., Wang, Kevin K.W., Wang, Michael Y., Wang, Minghao, Wang, Shelly, Wang, Tao, Wang, Tony R., Wang, Vincent Y., Waqas, Muhammad, Warf, Benjamin C., Weiner, Howard L., Weingart, Jon D., Weinstein, Lawrence, Weiss, Martin H., Weiss, Nirit, Welch, Babu G., Wellons, John C., III, Wen, Hung Tzu, Wen, Patrick Y., West, G. Alexander, Wewel, Joshua T., Whitehead, William E., Whiting, Alexander C., Whiting, Donald M., Wichmann, Thomas, Wilkinson, D. Andrew, Williams, Michael A., Williams-Medina, Alberto R., Williamson, Theresa, Wilson, Lindsay, Winer, Jesse L., Winfree, Christopher J., Winkler, Ethan A., Winn, H. Richard, Wintermark, Max, Wipplinger, Christoph, Witiw, Christopher D., Wolfla, Christopher E., Wolinsky, Jean-Paul, Wong, Eric T., Worrell, Gregory A., Wrensch, Margaret R., Wright, Christina H., Wu, Jau-Ching, Wu, Jenny, Wu, Kyle C., Wu, Pang Hung, Xu, David S., Xu, Linda Wei, Xu, Yifan, Xu, Zhen, Xu, Zhiyuan, Yaeger, Kurt A., Yahanda, Alexander T., Yan, Rachel E., Yan, Yuanqing, Yang, George L., Yasuno, Katsuhito, Yen, Chun-Po, Yokota, Kazuya, Yolcu, Yagiz Ugur, Young, Timothy P., Yu, Jennifer S., Yue, John K., Yuh, Esther L., Zabramski, Joseph M., Zacest, Andrew, Zacko, J. Christopher, Zada, Gabriel, Zafonte, Ross D., Zager, Eric L., Zakare-Fagbamila, Rasheedat T., Zakeri, Amanda, Zanotti, Bruno, Zawar, Ifrah, Zeineddine, Hussein A., Zellner, Elizabeth G., Zhan, Shikun, Zhang, Chencheng, Zhang, Michael, Zhang, Yingying, Zibly, Zion, Zigler, Jack E., Zipfel, Gregory J., Zipser, Carl Moritz, Zrinzo, Ludvic, and Zumofen, Daniel W.
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- 2023
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13. 264 - Radiosurgery Technique
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Lee, Cheng-Chia, Schlesinger, David J., and Sheehan, Jason P.
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- 2017
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14. Spatial shifts in frame-based Gamma Knife radiosurgery: A case for cone beam CT imaging as quality assurance using the Gamma Knife® Icon™
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Peach, M. Sean, Trifiletti, Daniel M., Dutta, Sunil W., Larner, James M., Schlesinger, David J., and Sheehan, Jason P.
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Physics Investigation - Abstract
Cone beam CT (CBCT) imaging has been integrated into the most recent version of the Leksell Gamma Knife for the primary purpose to facilitate fractionated therapy.This case study presents three patients where the CBCT system of the Gamma Knife Icon discovered potentially clinically significant frame shifts. In each case, patients were imaged with volumetric MR prior to stereotactic frame placement. Immediately following frame placement, diagnostic stereotactic CT imaging was acquired with a stereotactic indicator box attached to the frame. Following treatment planning and immediately before radiosurgery, a CBCT was acquired using the on-board imaging functionality of the Gamma Knife Icon, which provides a registration of the patient's anatomy to stereotactic space independent of that provided by the stereotactic frame/fiducials. Co-registration of the CT and CBCT provides an estimate of the difference between these two estimates of stereotactic coordinates. The vector magnitudes of the differences measured at the center of stereotactic space were 0.93mm, 2.64mm and 2.18 mm for Case 1, Case 2 and Case 3 respectively.Use of the CBCT functionality of the Gamma Knife Icon to verify the consistency of frame placement can prevent clinically significant targeting errors due to frame slippage or frame adapter mounting errors, and allows any required adjustments to be made without interrupting the overall treatment workflow.
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- 2018
15. Variability in spine radiosurgery treatment planning - results of an international multi-institutional study
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Toussaint, André, Richter, Anne, Mantel, Frederick, Flickinger, John C, Grills, Inga Siiner, Tyagi, Neelam, Sahgal, Arjun, Letourneau, Daniel, Sheehan, Jason P, Schlesinger, David J, Gerszten, Peter Carlos, Guckenberger, Matthias, Toussaint, André, Richter, Anne, Mantel, Frederick, Flickinger, John C, Grills, Inga Siiner, Tyagi, Neelam, Sahgal, Arjun, Letourneau, Daniel, Sheehan, Jason P, Schlesinger, David J, Gerszten, Peter Carlos, and Guckenberger, Matthias
- Abstract
BACKGROUND The aim of this study was to quantify the variability in spinal radiosurgery (SRS) planning practices between five international institutions, all member of the Elekta Spine Radiosurgery Research Consortium. METHODS Four institutions provided one representative patient case each consisting of the medical history, CT and MR imaging. A step-wise planning approach was used where, after each planning step a consensus was generated that formed the basis for the next planning step. This allowed independent analysis of all planning steps of CT-MR image registration, GTV definition, CTV definition, PTV definition and SRS treatment planning. In addition, each institution generated one additional SRS plan for each case based on intra-institutional image registration and contouring, independent of consensus results. RESULTS Averaged over the four cases, image registration variability ranged between translational 1.1 mm and 2.4 mm and rotational 1.1° and 2.0° in all three directions. GTV delineation variability was 1.5 mm in axial and 1.6 mm in longitudinal direction averaged for the four cases. CTV delineation variability was 0.8 mm in axial and 1.2 mm in longitudinal direction. CTV-to-PTV margins ranged between 0 mm and 2 mm according to institutional protocol. Delineation variability was 1 mm in axial directions for the spinal cord. Average PTV coverage for a single fraction18 Gy prescription was 87 ± 5 %; Dmin to the PTV was 7.5 ± 1.8 Gy averaged over all cases and institutions. Average Dmax to the PRV_SC (spinal cord + 1 mm) was 10.5 ± 1.6 Gy and the average Paddick conformity index was 0.69 ± 0.06. CONCLUSIONS Results of this study reflect the variability in current practice of spine radiosurgery in large and highly experienced academic centers. Despite close methodical agreement in the daily workflow, clinically significant variability in all steps of the treatment planning process was demonstrated. This may translate into differences in patient clinical outco
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- 2016
16. Dosimetric effects of Onyx embolization on Gamma Knife arteriovenous malformation dose distributions
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Schlesinger, David J., primary, Nordström, Håkan, additional, Lundin, Anders, additional, Xu, Zhiyuan, additional, and Sheehan, Jason P., additional
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- 2016
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17. Variability in spine radiosurgery treatment planning – results of an international multi-institutional study
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Toussaint, André, primary, Richter, Anne, additional, Mantel, Frederick, additional, Flickinger, John C., additional, Grills, Inga Siiner, additional, Tyagi, Neelam, additional, Sahgal, Arjun, additional, Letourneau, Daniel, additional, Sheehan, Jason P., additional, Schlesinger, David J., additional, Gerszten, Peter Carlos, additional, and Guckenberger, Matthias, additional
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- 2016
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18. Spatial shifts in frame-based Gamma Knife radiosurgery: A case for cone beam CT imaging as quality assurance using the Gamma Knife® Icon™.
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Peach, M. Sean, Trifiletti, Daniel M., Dutta, Sunil W., Larner, James M., Schlesinger, David J., and Sheehan, Jason P.
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RADIOSURGERY ,CONE beam computed tomography ,COMPUTED tomography ,RADIOTHERAPY ,STEREOTACTIC radiotherapy - Abstract
Background: Cone beam CT (CBCT) imaging has been integrated into the most recent version of the Leksell Gamma Knife for the primary purpose to facilitate fractionated therapy. Case description: This case study presents three patients where the CBCT system of the Gamma Knife Icon discovered potentially clinically significant frame shifts. In each case, patients were imaged with volumetric MR prior to stereotactic frame placement. Immediately following frame placement, diagnostic stereotactic CT imaging was acquired with a stereotactic indicator box attached to the frame. Following treatment planning and immediately before radiosurgery, a CBCT was acquired using the on-board imaging functionality of the Gamma Knife Icon, which provides a registration of the patient's anatomy to stereotactic space independent of that provided by the stereotactic frame/fiducials. Co-registration of the CT and CBCT provides an estimate of the difference between these two estimates of stereotactic coordinates. The vector magnitudes of the differences measured at the center of stereotactic space were 0.93mm, 2.64mm and 2.18 mm for Case 1, Case 2 and Case 3 respectively. Conclusions: Use of the CBCT functionality of the Gamma Knife Icon to verify the consistency of frame placement can prevent clinically significant targeting errors due to frame slippage or frame adapter mounting errors, and allows any required adjustments to be made without interrupting the overall treatment workflow. [ABSTRACT FROM AUTHOR]
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- 2018
19. Tracking brain motion during the cardiac cycle using spiral cine-DENSE MRI
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Zhong, Xiaodong, Meyer, Craig H., Schlesinger, David J., Sheehan, Jason P., Epstein, Frederick H., Larner, James M., Benedict, Stanley H., Read, Paul W., Sheng, Ke, and Cai, Jing
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Adult ,Male ,Time Factors ,Radiation Imaging Physics ,Movement ,cardiovascular system ,Image Processing, Computer-Assisted ,Brain ,Feasibility Studies ,Humans ,Magnetic Resonance Imaging, Cine ,Heart ,Algorithms - Abstract
Cardiac-synchronized brain motion is well documented, but the accurate measurement of such motion on the pixel-by-pixel basis has been hampered by the lack of proper imaging technique. In this article, the authors present the implementation of an autotracking spiral cine displacement-encoded stimulation echo (DENSE) magnetic resonance imaging (MRI) technique for the measurement of pulsatile brain motion during the cardiac cycle. Displacement-encoded dynamic MR images of three healthy volunteers were acquired throughout the cardiac cycle using the spiral cine-DENSE pulse sequence gated to the R wave of an electrocardiogram. Pixelwise Lagrangian displacement maps were computed, and 2D displacement as a function of time was determined for selected regions of interests. Different intracranial structures exhibited characteristic motion amplitude, direction, and pattern throughout the cardiac cycle. Time-resolved displacement curves revealed the pathway of pulsatile motion from brain stem to peripheral brain lobes. These preliminary results demonstrated that the spiral cine-DENSE MRI technique can be used to measure cardiac-synchronized pulsatile brain motion on the pixel-by-pixel basis with high temporal/spatial resolution and sensitivity.
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- 2009
20. Contributors
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Aarabi, Bizhan, Abbott, Rick, Abd-El-Barr, Muhammad M., Abel, Taylor J., Abruzzo, Todd A., Acar, Feridun, Achey, Rebecca L., Ackerman, Paul D., Adams, Hadie, Adappa, Nithin D., Adelson, P. David, Aguirre-Padilla, David H., Ahmed, Raheel, Ahn, Edward S., Ailon, Tamir T., Ain, Michael C., Aisiku, Imoigele P., Alaraj, Ali, AlBakry, Amr, Albuquerque, Felipe C., Alexander, Brian M., Alexander, Michael J., Alexandrov, Andrei V., Ali, Zarina S., Al-Khalili, Kenan, Al-Mefty, Ossama, Almefty, Kaith K., Almefty, Rami, Alterman, Ron L., Amenta, Peter S., Ames, Christopher P., Amin-Hanjani, Sepideh, Ammirati, Mario, Andaluz, Norberto, Anderson, Richard C.E., Andrade, Pablo, Angevine, Peter D., Ansari, Shaheryar F., Ares, William J., Arle, Jeffrey E., Armonda, Rocco A., Arnaout, Omar, Arnaud, Eric, Arnold, Paul M., Assina, Rachid, Aszmann, Oskar C., Attenello, Frank J., III, Badhiwala, Jetan H., Baehring, Joachim M., Baggott, Christopher D., Bagić, Anto, Bahgat, Diaa, Bailes, Julian E., Bain, Mark, Ball, Perry A., Baltuch, Gordon H., Baraban, Scott C., Barak, Tanyeri, Barani, Igor J., Barbagallo, Giuseppe M.V., Barbaro, Nicholas M., Barker, Frederick G., II, Barnett, Gene H., Barone, Constance M., Barrow, Daniel Louis, Bassani, Luigi, Batchelor, Tracy T., Batista, Nuno, Batjer, H. Hunt, Baum, Griffin R., Beattie, Michael S., Beaumont, Andrew, Becker, Danielle A., Beckman, Joshua M., Becske, Tibor, Bederson, Joshua B., Beisse, Rudolf W., Bekelis, Kimon, Bell, Randy S., Belzberg, Allan J., Benarroch, Eduardo E., Bendok, Bernard R., Benet, Arnau, Berenstein, Alejandro, Berger, Mitchel S., Bergsneider, Marvin, Bertalanffy, Helmut, Bhatnagar, Saurabha, Bi, Wenya Linda, Birk, Harjus Singh, Bishop, Allen T., Blakeley, Jaishri O., Blomstedt, Patric, Bolinger, Bryan D., Bonney, Phillip A., Boomsaad, Zackary E., Boop, Frederick A., Borg, Nicholas, Boszczyk, Bronek M., Botelho, Ricardo Vieira, Bou-Haidar, Pascal, Bowyer, Susan M., Bragg, Taryn McFadden, Brem, Henry, Brem, Steven, Bresnahan, Jacqueline C., Brinkmann, Benjamin H., Brînzeu, Andrei, Britz, Gavin W., Brockmeyer, Douglas L., Browd, Samuel R., Brown, Desmond A., Brown, Martin, Brown, Matthew T., Brown, Robert D., Jr., Bruce, Jeffrey N., Brunstrom-Hernandez, Janice E., Brunswick, Andrew, Buell, Thomas J., Bullock, M. Ross, Burchiel, Kim J., Burrows, Anthony M., Bydon, Mohamad, Byrne, Richard W., Cahill, Daniel P., Cahill, Kevin S., Calcagnotto, Maria Elisa, Caplan, Justin M., Cascino, Gregory D., Castinetti, Frederic, Cawley, C. Michael, Cernak, Ibolja, Certo, Francesco, Cetas, Justin S., Chan, Michael D., Chanda, Amitabha, Chang, Edward F., Chang, Steven D., Charbel, Fady T., Chari, Aswin, Chaudhary, Navjot, Chauvel, Patrick, Chen, Kevin S., Chen, Liang, Cheng, Joseph S., Cheng, Yuwei, Cheung, Kenneth M.C., Chiocca, E. Antonio, Cho, Catherine, Chou, Dean, Choudhri, Omar, Christian, Cindy W., Claassen, Jan, Claus, Elizabeth B., Cleary, Daniel R., Cohen, Alan R., Collins, John, Connolly, E. Sander, Jr., Cooke, Jonathon, Coppens, Jeroen R., Corcos, Daniel M., Coric, Domagoj, Cornips, Erwin M.J., Cosgrove, G. Rees, Couldwell, William T., Crino, Peter B., Crofton, Andrew, Cullen, D. Kacy, Curry, Brian P., da Silva, Erasmo Barros, Jr., Dailey, Andrew T., Dallapiazza, Robert F., Dalyai, Richard Tyler, Danan, Deepa, Daniels, David J., Darsaut, Tim E., Dash, Alexander, Dashnaw, Matthew L., David, Carlos A., David, David J., Day, Arthur L., De la Garza-Ramos, Rafael, De Salles, Antonio A.F., Dea, Nicolas, Decker, Matthew, Del Brutto, Oscar H., Delman, Bradley N., DeLong, Mahlon R., DeMonte, Franco, Deogaonkar, Milind, Desai, Arati, Desai, Virendra R., Di Rocco, Federico, Diebo, Bassel G., DiLuna, Michael L., DiMeco, Francesco, Dirks, Peter, Dlouhy, Brian J., Doshi, Amish H., Drake, James M., Drofa, Alexander, Ducruet, Andrew F., Duffau, Hugues, Duhaime, Ann-Christine, Dumont, Aaron S., Dunn, Gavin P., Dunn, Ian F., Dusick, Joshua R., Eberwine, James H., Eboli, Paula, Eckardt, Gerald W., Edwards, Michael S.B., Edwards, Richard J., Elder, J. Bradley, Elhammady, Mohamed Samy A., Elias, W. Jeffrey, Ellis, Jason A., Elmadhoun, Tarek M.I., Emch, Todd M., Emerson, Samuel, Ene, Chibawanye, Englot, Dario J., Eskandari, Ramin, Ewend, Matthew G., Fakurnejad, Shayan, Falavigna, Asdrubal, Fan, Yi, Farina, Dario, Farrell, Christopher J., Fehlings, Michael G., Feigin, Valery, Feldman, Eva L., Feldstein, Neil, Feng, James E., Fenno, Lief E., Ferguson, Sherise D., de Oliveira, Matheus Fernandes, Figueroa, Javier M., Figueroa, Juan J., Filler, Aaron G., Findlay, J. Max, Finn, Michael A., Finnell, Richard H., Fisher, Charles G., Flamm, Eugene S., Flemming, Kelly D., Flores-Sarnat, Laura, Follett, Kenneth A., Foreman, Paul M., Foster, Kimberly A., Freeze, Benjamin S., Fried, Itzhak, Friedlander, Robert M., Fry, Donald E., Fu, Kai-Ming Gregory, Fulkerson, Daniel H., Fuller, Gregory N., Fusco, Matthew R., Galvan, Adriana, Gandhoke, Gurpreet S., Garcia, Hector H., Gardner, Paul A., Garton, Hugh, Gavin, Cormac G., Gaynor, Brandon G., George, Timothy M., Georgoulis, George, Gerard, Carter S., Gerke, Luke, Gerosa, Massimo, Gerszten, Kristina, Gerszten, Peter C., Ghatan, Saadi, Ghobrial, George M., Ghosh, Chaitali, Giacobbe, Peter, Gianaris, Thomas J., Giglio, Pierre, Gilad, Ronit, Gjedde, Albert H., Göçmen, Selçuk, Godzik, Jakub, Goel, Atul, Gogela, Steven L., Gokaslan, Ziya L., Goldstein, Hannah E., Golfinos, John G., Gologorsky, Yakov, Golshani, Kiarash, Gonzalez, Nestor R., Gonzalez-Martinez, Jorge, Goodden, John, Goodman, J. Clay, Goodrich, James Tait, Goodwin, C. Rory, Gordon, David S., Gorgulho, Alessandra, Goumnerova, Liliana C., Goyal, Anshit, Grady, M. Sean, Grafman, Jordan H., Gragnaniello, Cristian, Grande, Andrew W., Grant, Gerald A., Grant, Ryan A., Griessenauer, Christoph J., Groff, Michael W., Gross, Robert E., Grossberg, Jonathan A., Grossman, Aaron W., Grossman, Rachel, Groves, Mari L., Gruenberg, Marcelo Fernando, Gunel, Jennifer Moliterno, Günel, Murat, Gupta, Nalin, Haddad, Georges F., Haglund, Michael M., Haines, Stephen J., Haldeman, Clayton L., Halvorson, Kyle G., Hamberger, Marla J., Haq, Ihtsham U., Haranhalli, Neil, Harbaugh, Robert E., Hariz, Marwan, Harrigan, Mark R., Harrop, James S., Härtl, Roger, Harwell, Daniel M., Hasan, David M., Hashemiyoon, Rowshanak, Hassaneen, Wael, Hawryluk, Gregory W.J., Hayward, Richard David, He, Lucy, Healy, Andrew T., Heary, Robert F., Heimberger, Amy B., Prof. Dr. med., Heini, Heinricher, Mary M., Henrikson, Karl J., Heros, Roberto C., Herrup, Karl, Hervey-Jumper, Shawn, Heuer, Gregory G., Higuchi, Yoshinori, Gilmer, Holly S., Hirsch, Lawrence J., Hoffer, S. Alan, Holland, Eric, Holland, Ryan, Hongo, Kazuhiro, Horisawa, Shiro, Horner, Philip J., Houseman, Clifford M., Howard, Matthew A., III, Hsueh, Brian, Huang, Judy, Huang, Michael C., Huang, Raymond Y., Hudgins, Eric, Hunt, Matthew A., Hurlbert, R. John, Hutchinson, Peter J., Huttner, Anita, Hwang, Steven W., Iliff, Jeffrey J., Ingram, Susan L., Isaias, Ioannis U., Iskandar, Bermans J., Iyer, Aditya K., Jacob, R. Patrick, Jada, Ajit, Jadhav, Ashutosh P., Jaffer, Hayder, Jakacki, Regina I., Jallo, George I., Jallo, Jack I., Jamil, Osama, Jane, John A., Jr., Jane, John A., Sr., Janigro, Damir, Jankowitz, Brian T., Jea, Andrew H., Jeelani, Owase, Jehi, Lara, Jellinger, Kurt A., Jho, Diana, Jimenez, David F., Jo, Jasmin T., Johanson, Conrad E., Johnson, Luke A., Jones, Adrian C., Jones, Kristen E., Joseph, Jacob R., Jovin, Tudor G., Kalani, M. Yashar S., Kalanithi, Paul S.A., Kalfas, Iain H., Kalnins, Aleksandrs Uldis, Kalra, Ricky Raj Singh, Kamath, Ashwin A., Kang, Daniel G., Kang, James D., Kanter, Adam S., Kaplitt, Michael G., Karimi, Reza J., Kasliwal, Manish K., Kawasaki, Hiroto, Kelleher, John Paul, Kellner, Christopher P., Kemeny, Andras A., Kennedy, Benjamin C., Kestle, John R.W., Khan, Imad Saeed, Khan, Nadia, Khurana, Vini G., Kim, Dong Gyu, Kim, Dong H., Kim, Irene, Kim, Jin Wook, Kim, Louis J., Kim, Paul K., Kim, Thomas Aquinas, Kirsch, Wolff, Kitchen, Neil D., Klaas, James P., Klein, Joshua P., Kliot, Michel, Knightly, John J., Knopman, Jared, Ko, Andrew L., Koerner, John D., Kokoszka, Malgosia A., Kolias, Angelos G., Korja, Miikka, Kosztowski, Thomas, Krauss, Joachim K., Krishna, Chandan, Krishna, Vibhor, Krishnaney, Ajit A., Kubben, Pieter L., Kuhn, Jens, Kulkarni, Abhaya V., Kumar, Gomatam R. Vijay, Kuntz, Charles, IV, Kuo, Jeffrey V., Kwan, Kenny, La Marca, Frank, Laack, Nadia N. Issa, Ladha, Alim M., Lafage, Virginie, Lam, Arthur M., Lamki, Tariq, Lang, Frederick F., Lanzino, Giuseppe, Larson, Paul, Lau, Catherine Y., Lau, Darryl, Lavine, Sean D., Lawler, Sean E., Laws, Edward R., Jr., Lawton, Michael T., Laxpati, Nealen G., Lazarus, Joash T., Le, Peter D., Lebed, Brett D., Lee, Cheng-Chia, Lee, Sangmi, Lee, Young M., Lehman, Ronald A., Jr., Lenke, Lawrence G., Leuthardt, Eric C., Levin, Emily Lehmann, Levitt, Michael R., Lewis, Evan M., Li, Dianyou, Liang, Lydia J., Liauw, Jason, Lichtenbaum, Roger, Limbrick, David D., Jr., Lin, Kant Y., Lingsma, Hester F., Linskey, Mark E., Lipsman, Nir, Litvak, Zachary N., Liu, James K., Liu, Kenneth C., Liu, Wei, Lizarraga, Karlo J., Lober, Robert M., Loftus, Christopher M., Lonser, Russell R., Louvi, Angeliki, Lozano, Andres M., Luciano, Mark G., Lukas, Rimas V., Lund, Teija, Ma, Lijun, Ma, Tracy S., Maas, Andrew I.R., Macdonald, R. Loch, Mack, Stephen C., MacLachlan, Lara S., Macyszyn, Luke, Magarik, Jordan A., Maggio, Dominic, Magistretti, Pierre J., Mahaney, Kelly B., Maher, Cormac O., Mahmoodi, Ramin, Mahmoudi, Babak, Malessy, Martijn J.A., Mallucci, Conor, Mangano, Francesco T., Maniker, Allen H., Manley, Geoffrey T., Manolidis, Spiros, Marchac, Daniel, Marchione, Joseph, Marcus, Joshua, Maroon, Joseph C., Martin, Alastair, Martin, Neil A., Mascitelli, Justin R., Mathur, Amit, Maulucci, Christopher M., Mazur, Marcus D., Mazwi, Nicole, McAllister, James P., II, McClain, Craig D., McCutcheon, Ian E., McDougall, Cameron G., McEvoy, Andrew W., McGoldrick, Patricia E., McGovern, Robert A., III, McKhann, Guy M., II, Meaney, David F., Medel, Ricky, Mehta, Minesh P., Melega, William P., Menezes, Arnold H., Mertens, Patrick, Meyer, Fredric B., Meyer, R. Michael, IV, Meyer, Scott A., Meyers, Emma, Meyers, Philip M., Midha, Rajiv, Milano, Jerônimo Buzetti, Miller, Catherine, Miller, Charles A., Miller, Jonathan P., Miller, Neil R., Mirza, Farhan A., Miserocchi, Anna, Misra, Basant K., Missios, Symeon, Miyashiro, Kevin Y., Mizuno, Junichi, Mocco, J., Modic, Michael T., Moeller, Jeremy J., Mokin, Maxim, Monteith, Stephen J., Moon, Karam, Morales-Valero, Saul F., Morcos, Jacques J., Morgan, Michael Kerin, Moses, Ziev B., Moss, S. David, Moussazadeh, Nelson, Muizelaar, J. Paul, Mukherjee, Pratik, Mukundan, Srinivasan, Jr., Mummaneni, Praveen V., Munich, Stephan A., Muraszko, Karin, Murray-Ortiz, Gisela, Mussi, Antônio C.M., Nagel, Sean J., Nagy, Gábor, Najm, Imad M., Nakaji, Peter, Nakajima, Takeshi, Nakashima, Hiroaki, Nater, Anick, Navarro-Ramirez, Rodrigo, Nduom, Edjah K., Nelp, Taylor B., Nerva, John D., Nery, Breno, Newell, David W., Ng, Angela Li Ching, Nicholas, M. Kelly, Niimi, Yasunari, Nimjee, Shahid M., North, Richard B., Nowell, Mark, Nurmikko, Turo J., Nuwer, Marc R., Oakes, W. Jerry, Ochiai, Taku, Ogilvy, Christopher S., Oh, Michael Y., Oh, Nathan, Okonkwo, David O., Okun, Michael S., Oldfield, Edward H., Olivi, Alessandro, O'Neill, Francis, Orgill, Dennis P., Osbun, Joshua W., Özduman, Koray, Pacia, Steven V., Pai, Nikhil S., Pain, Margaret, Palacios, Eva M., Palmer, James N., Pamir, M. Necmettin, Pan, Edward, Panczykowski, David M., Panov, Fedor E., Parajón, Avelino, Paramasivam, Srinivasan, Parent, Andrew D., Park, Michael S., Park, Min S., Park, Paul, Park, T.S., Parsa, Andrew T., Partington, Michael D., Patel, Akash J., Patel, Aman B., Patel, Vimal, Patil, Parag G., Payne, Russell, Penn, Richard Deren, Pennicooke, Brenton H., Perez, Augustus J., Perin, Alessandro, Perlmutter, Joel S., Persing, John A., Petersen, Erika A., Peterson, Eric C., Petraglia, Anthony L., Pham, Martin, Piazza, Matthew A., Piepmeier, Joseph M., Pilcher, Webster H., Pinckard-Dover, Heather N., Pineda, José A., Pinter, Joseph D., Pisapia, Jared M., Pisculli, Mary L., Pittman, Thomas, Pohl, Pedro H.I., Pollack, Ian F., Pollock, Bruce E., Post, Kalmon D., Potter, Wyatt, Potts, Matthew B., Pouratian, Nader, Pradilla, Gustavo, Prager, Briana C., Prestigiacomo, Charles J., Proctor, Mark R., Prolo, Laura M., Prost, Robert W., Puduvalli, Vinay K., Purger, David, Quiñones-Hinojosa, Alfredo, Rahal, Jason Pierce, Ram, Zvi, Ranalli, Nathan J., Rangel-Castilla, Leonardo, Raper, Daniel M.S., Rapoport, Benjamin I., Raskin, Jeffrey S., Raslan, Ahmed M., Rasmussen, Peter, Rasouli, Jonathan, Ravanpay, Ali C., Ravindra, Vijay M., Ray, Wilson Z., Raz, Eytan, Raza, Shaan M., Régis, Jean, Reilly, Peter L., Reith, Florence C.M., Renier, Dominique, Resnick, Daniel K., Reynolds, Renée, Rezai, Ali, Rhines, Laurence D., Rhoton, Albert L., Jr., Ribalta, Teresa, Ricci, Joseph A., Richardson, R. Mark, Riggins, Callen J., Riggins, Gregory J., Riina, Howard A., Rincon-Torroella, Jordina, Ringer, Andrew J., Riva-Cambrin, Jay, Roark, Christopher D., Roberts, David W., Robertson, Claudia S., Robertson, Jon H., Robinson, Shenandoah, Roche, Aidan D., Roche, Pierre-Hugues, Rodríguez-Hernández, Ana, Roguski, Marie, Roland, Jarod L., Rolston, John D., Root, Brandon K., Rosenberg, William S., Rosenow, Joshua M., Rosenthal, Guy, Rosenwasser, Robert H., Rosner, Michael K., Rovner, Eric S., Rucker, Janet C., Russell, Stephen M., Russin, Jonathan J., Rutka, James T., Safain, Mina G., Sagher, Oren, Sahgal, Arjun, Saigal, Rajiv, Saito, Nobuhito, Salminger, Stefan, Samdani, Amer F., Sammartino, Francesco, Sanai, Nader, Sanborn, Matthew R., Sandler, Adam L., Sansur, Charles A., Santarius, Thomas, Santiago, Paul, Santiago-Sim, Teresa, José Santos de Moraes, Osmar, Sarkiss, Christopher A., Sarnat, Harvey B., Sarris, Christina, Sawaya, Raymond, Scheer, Justin K., Scheld, W. Michael, Schiff, Nicholas D., Schlesinger, David J., Schmidt, Meic H., Schmitt, Paul J., Schramm, Johannes, Schwab, Frank J., Sciubba, Daniel M., Scott, R. Michael, Scranton, Robert A., Seifert, Volker, Selden, Nathan R., Sellin, Jonathan N., Selman, Warren R., Serafini, Sandra, Serizawa, Toru, Shaffrey, Christopher I., Sr., Shah, Kushal J., Shah, Lubdha M., Shah, Manish N., Shahlaie, Kiarash, Shapira, Yuval, Shapiro, Maksim, Sharma, Deepak, Sharma, Mayur, Sharma, Mohan Raj, Shaw, Andrew, Sheehan, Jason P., Sheehan, Jonas M., Shiflett, James M., Shilpakar, Sushil Krishna, Shils, Jay L., Shin, Alexander Y., Shin, Samuel S., Siddiqui, Adnan H., Siddiqui, Mustafa S., Silvestri, David M., Sindou, Marc, Singer, Robert J., Singh, Jeffrey M., Singh, Manish K., Sivakumar, Walavan, Slavin, Justin, Smith, Edward R., Smith, Justin S., Smith, Timothy R., Smith, Yoland, Solomon, Robert A., Sonabend, Adam M., Sonntag, Volker K.H., Sorenson, Jeffrey M., Soriano, Sulpicio G., Soriano-Baron, Hector, Souweidane, Mark M., Sowa, Gwendolyn A., Spatola, Giorgio, Spears, Julian, Spencer, Dennis D., Spetzler, Robert F., Spinner, Robert J., St. Clair, Eric G., Starke, Robert M., Starr, Philip, Stefko, S. Tonya, Stein, Sherman C., Steinberg, Gary K., Stephens, Bradley H., Stephens, Frederick L., Stern, Matthew A., Steyerberg, Ewout W., Stieg, Philip E., Stone, Scellig S.D., Strom, Russell G., Strowd, Roy E., III, Sughrue, Michael E., Suh, John H., Suki, Dima, Sulaiman, Wale A.R., Sun, Bomin, Tagliati, Michele, Taira, Takaomi, Takagi, Yasushi, Tamargo, Rafael J., Tanaka, Shota, Tandon, Nitin, Tanweer, Omar, Tate, Jessica A., Tate, Matthew C., Tatsui, Claudio E., Taylor, Blake E.S., Taylor, Michael D., Telian, Steven A., Tempel, Zachary J., Teo, Charles, Tessier, Jeffrey M., Than, Khoi D., Theadom, Alice, Theodore, Nicholas, Thompson, B. Gregory, Jr., Tilton, Ann H., Timmons, Shelly D., Tomycz, Nestor D., Torres-Reveron, Juan, Toth, Gabor, Toussaint, Charles P., Tran, Duc A., Trapp, Bruce D., Tubbs, R. Shane, Tunkel, Allan R., Türe, Ugur, Hassoun Turkmani, Ali, Uribe, Juan S., Ushe, Mwiza, Vaccaro, Alexander R., van den Bent, Martin J., Van Gompel, Jamie J., van Overbeeke, J.J., van Santbrink, Henk, Vasquez, Ciro, Vasudeva, Viren S., Vellimana, Ananth K., Verlicchi, Angela, Vialle, Emiliano, Viapiano, Mariano S., Vira, Shaleen, Virk, Michael S., Visser-Vandewalle, Veerle, Vitek, Jerrold L., Vo, Nam, Vogelbaum, Michael A., Volpini, Matthew, Wackym, P. Ashley, Wadhwa, Rishi, Wainwright, Mark S., Waldau, Ben, Walker, Marion L., Wallace, M. Christopher, Wallace, Scott A., Walsh, Kyle M., Wang, Huan, Wang, Michael Y., Wang, Shelly, Wang, Tony R., Wang, Vincent Y., Wang, Xin, Warnick, Ronald E., Weil, Robert J., Weiner, Howard L., Weingart, Jon D., Weiss, Martin H., Weiss, Nirit, Weller, Michael, Wellons, John C., III, Wen, Hung Tzu, Wen, Patrick Y., West, G. Alexander, White, Jonathan, Whiting, Alexander C., Whiting, Donald M., Wichmann, Thomas, Wildrick, David M., Wilkinson, D. Andrew, Winer, Jesse L., Winfree, Christopher J., Winkler, Ethan A., Winn, H. Richard, Wisoff, Jeffrey H., Witsch, Jens, Wolf, Steven M., Wolfla, Christopher E., Wolinsky, Jean-Paul, Wong, Cyrus C., Wong, Eric T., Wrensch, Margaret R., Wu, Jau-Ching, Xu, Linda Wei, Xu, Zhiyuan, Yan, Carol H., Yap, Edward, Yarbrough, Chester K., Yasuno, Katsuhito, Yavin, Daniel, Yener, Ulaş, Yonekawa, Yasuhiro, Young, Timothy P., Youngblood, Mark W., Youngerman, Brett E., Yu, Jennifer S., Yue, John K., Yuh, Esther L., Zabramski, Joseph M., Zacest, Andrew C., Zacko, J. Christopher, Zada, Gabriel, Zadicario, Eyal, Zadnik, Patricia Leigh, Zafonte, Ross D., Zager, Eric L., Zanotti, Bruno, Zellner, Elizabeth G., Zhan, Shikun, Zhang, Chencheng, Zhang, Xiaoxiao, Zhang, Y. Jonathan, Zisakis, Athanasios K., Zuckerman, Scott L., Zumofen, Daniel W., and Zwienenberg-Lee, Marike
- Published
- 2017
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21. Cranial nerve dysfunction following Gamma Knife surgery for pituitary adenomas: long-term incidence and risk factors
- Author
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Cifarelli, Christopher P., primary, Schlesinger, David J., additional, and Sheehan, Jason P., additional
- Published
- 2012
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22. Initial Experience with the eXtend System: A Relocatable Frame System for Multiple-Session Gamma Knife Radiosurgery
- Author
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Sayer, Faisal T., primary, Sherman, Jonathan H., additional, Yen, Chun-Po, additional, Schlesinger, David J., additional, Kersh, Ronald, additional, and Sheehan, Jason P., additional
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- 2011
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23. Timing and risk factors for new brain metastasis formation in patients initially treated only with Gamma Knife surgery
- Author
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Sheehan, Jason P., primary, Yen, Chun-Po, additional, Nguyen, James, additional, Rainey, Jessica A., additional, Dassoulas, Kasandra, additional, and Schlesinger, David J., additional
- Published
- 2011
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24. Leksell GammaPlan version 10.0 preview: performance of the new inverse treatment planning algorithm applied to Gamma Knife surgery for pituitary adenoma
- Author
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Schlesinger, David J., primary, Sayer, Faisal T., additional, Yen, Chun-Po, additional, and Sheehan, Jason P., additional
- Published
- 2010
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- View/download PDF
25. Gamma Knife surgery for arteriovenous malformations in children
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Yen, Chun Po, primary, Monteith, Stephen J., additional, Nguyen, James H., additional, Rainey, Jessica, additional, Schlesinger, David J., additional, and Sheehan, Jason P., additional
- Published
- 2010
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26. Gamma knife radiosurgery for brain metastasis of nonsmall cell lung cancer: Is there a difference in outcome between morning and afternoon treatment?
- Author
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Rahn, Douglas A., primary, Ray, Dibyendu K., additional, Schlesinger, David J., additional, Steiner, Ladislau, additional, Sheehan, Jason P., additional, O'Quigley, John M., additional, and Rich, Tyvin, additional
- Published
- 2010
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27. Stereotactic body radiation therapy: The report of AAPM Task Group 101
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Benedict, Stanley H., primary, Yenice, Kamil M., additional, Followill, David, additional, Galvin, James M., additional, Hinson, William, additional, Kavanagh, Brian, additional, Keall, Paul, additional, Lovelock, Michael, additional, Meeks, Sanford, additional, Papiez, Lech, additional, Purdie, Thomas, additional, Sadagopan, Ramaswamy, additional, Schell, Michael C., additional, Salter, Bill, additional, Schlesinger, David J., additional, Shiu, Almon S., additional, Solberg, Timothy, additional, Song, Danny Y., additional, Stieber, Volker, additional, Timmerman, Robert, additional, Tomé, Wolfgang A., additional, Verellen, Dirk, additional, Wang, Lu, additional, and Yin, Fang-Fang, additional
- Published
- 2010
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- View/download PDF
28. Tracking brain motion during the cardiac cycle using spiral cine-DENSE MRI
- Author
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Zhong, Xiaodong, primary, Meyer, Craig H., additional, Schlesinger, David J., additional, Sheehan, Jason P., additional, Epstein, Frederick H., additional, Larner, James M., additional, Benedict, Stanley H., additional, Read, Paul W., additional, Sheng, Ke, additional, and Cai, Jing, additional
- Published
- 2009
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- View/download PDF
29. The role of medical physicists in developing stereotactic radiosurgery
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Benedict, Stanley H., primary, Bova, Frank J., additional, Clark, Brenda, additional, Goetsch, Steven J., additional, Hinson, William H., additional, Leavitt, Dennis D., additional, Schlesinger, David J., additional, and Yenice, Kamil M., additional
- Published
- 2008
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30. Role of RecA in DNA damage repair inDeinococcus radiodurans
- Author
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Schlesinger, David J., primary
- Published
- 2007
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31. Possible Origins of CTnBST, a Conjugative Transposon Found Recently in a Human Colonic Bacteroides Strain
- Author
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Schlesinger, David J., primary, Shoemaker, Nadja B., additional, and Salyers, Abigail A., additional
- Published
- 2007
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32. Social Skills Training in Groups with Developmentally Disabled Adults
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Hall, James A., primary, Schlesinger, David J., additional, and Dineen, John P., additional
- Published
- 1997
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33. Segmentation of volumetric medical imagery using multiple geodesic-based active surfaces
- Author
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Schlesinger, David J., primary, Snell, John W., additional, Mansfield, Lois E., additional, Brookeman, James R., additional, Ortega, James M., additional, and Kassell, Neal F., additional
- Published
- 1996
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34. Segmentation of cortical surface and interior brain structures using active-surface/active-volume templates.
- Author
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Schlesinger, David J., Snell, John W., Mansfield, Lois E., Brookeman, James R., Downs III, J. H., Ortega, James M., and Kassell, Neal F.
- Published
- 1997
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- View/download PDF
35. Segmentation of volumetric medical imagery using multiple geodesic-based active surfaces.
- Author
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Schlesinger, David J., Snell, John W., Mansfield, Lois E., Brookeman, James R., Ortega, James M., and Kassell, Neal F.
- Published
- 1996
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- View/download PDF
36. Tracking brain motion during the cardiac cycle using spiral cine-DENSE MRI.
- Author
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Xiaodong Zhong, Meyer, Craig H., Schlesinger, David J., Sheehan, Jason P., Epstein, Frederick H., Larner, James M., Benedict, Stanley H., Read, Paul W., Ke Sheng, and Jing Cai
- Subjects
BRAIN ,DIAGNOSTIC imaging ,HEART beat ,OPTICAL resolution ,MEDICAL physics - Abstract
Cardiac-synchronized brain motion is well documented, but the accurate measurement of such motion on the pixel-by-pixel basis has been hampered by the lack of proper imaging technique. In this article, the authors present the implementation of an autotracking spiral cine displacement-encoded stimulation echo (DENSE) magnetic resonance imaging (MRI) technique for the measurement of pulsatile brain motion during the cardiac cycle. Displacement-encoded dynamic MR images of three healthy volunteers were acquired throughout the cardiac cycle using the spiral cine-DENSE pulse sequence gated to the R wave of an electrocardiogram. Pixelwise Lagrangian displacement maps were computed, and 2D displacement as a function of time was determined for selected regions of interests. Different intracranial structures exhibited characteristic motion amplitude, direction, and pattern throughout the cardiac cycle. Time-resolved displacement curves revealed the pathway of pulsatile motion from brain stem to peripheral brain lobes. These preliminary results demonstrated that the spiral cine-DENSE MRI technique can be used to measure cardiac-synchronized pulsatile brain motion on the pixel-by-pixel basis with high temporal/spatial resolution and sensitivity. [ABSTRACT FROM AUTHOR]
- Published
- 2009
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- View/download PDF
37. Anniversary Paper: The role of medical physicists in developing stereotactic radiosurgery.
- Author
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Benedict, Stanley H., Bova, Frank J., Clark, Brenda, Goetsch, Steven J., Hinson, William H., Leavitt, Dennis D., Schlesinger, David J., and Yenice, Kamil M.
- Subjects
PHYSICISTS ,RADIOSURGERY ,RADIOTHERAPY ,STEREOTAXIC techniques ,RESEARCH & development ,COMMERCIALIZATION ,MEDICAL radiology ,MEDICAL physics - Abstract
This article is a tribute to the pioneering medical physicists over the last 50 years who have participated in the research, development, and commercialization of stereotactic radiosurgery (SRS) and stereotactic radiotherapy utilizing a wide range of technology. The authors have described the evolution of SRS through the eyes of physicists from its beginnings with the Gamma Knife™ in 1951 to proton and charged particle therapy; modification of commercial linacs to accommodate high precision SRS setups; the multitude of accessories that have enabled fine tuning patients for relocalization, immobilization, and repositioning with submillimeter accuracy; and finally the emerging technology of SBRT. A major theme of the article is the expanding role of the medical physicist from that of advisor to the neurosurgeon to the current role as a primary driver of new technology that has already led to an adaptation of cranial SRS to other sites in the body, including, spine, liver, and lung. SRS continues to be at the forefront of the impetus to provide technological precision for radiation therapy and has demonstrated a host of downstream benefits in improving delivery strategies for conventional therapy as well. While this is not intended to be a comprehensive history, and the authors could not delineate every contribution by all of those working in the pursuit of SRS development, including physicians, engineers, radiobiologists, and the rest of the therapy and dosimetry staff in this important and dynamic radiation therapy modality, it is clear that physicists have had a substantial role in the development of SRS and theyincreasingly play a leading role in furthering SRS technology. [ABSTRACT FROM AUTHOR]
- Published
- 2008
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- View/download PDF
38. Role of RecA in DNA damage repair in Deinococcus radiodurans.
- Author
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Schlesinger, David J.
- Subjects
- *
DEINOCOCCUS , *GRAM-positive bacteria , *DNA repair , *BIOCHEMICAL genetics , *DNA damage , *AMINO acids , *ESCHERICHIA coli , *MICROBIOLOGY , *BIOLOGY - Abstract
It has been shown previously that the RecA protein of Deinococcus radiodurans plays a unique role in the repair of DNA damage in this highly DNA damage-resistant organism. Despite the high level of amino-acid identity, previous work has shown that Escherichia coli RecA does not complement D. radiodurans RecA mutants, further suggesting the uniqueness of D. radiodurans RecA. The work presented here shows that E. coli RecA does in fact provide partial complementation to a D. radiodurans RecA null mutant, suggesting that the RecA protein from D. radiodurans may not be as unique as believed previously. [ABSTRACT FROM AUTHOR]
- Published
- 2007
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39. Spatial shifts in frame-based Gamma Knife radiosurgery: A case for cone beam CT imaging as quality assurance using the Gamma Knife® Icon™.
- Author
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Peach, M. Sean, Trifiletti, Daniel M., Dutta, Sunil W., Larner, James M., Schlesinger, David J., and Sheehan, Jason P.
- Subjects
- *
RADIOSURGERY , *CONE beam computed tomography , *COMPUTED tomography , *RADIOTHERAPY , *STEREOTACTIC radiotherapy - Abstract
Background: Cone beam CT (CBCT) imaging has been integrated into the most recent version of the Leksell Gamma Knife for the primary purpose to facilitate fractionated therapy. Case description: This case study presents three patients where the CBCT system of the Gamma Knife Icon discovered potentially clinically significant frame shifts. In each case, patients were imaged with volumetric MR prior to stereotactic frame placement. Immediately following frame placement, diagnostic stereotactic CT imaging was acquired with a stereotactic indicator box attached to the frame. Following treatment planning and immediately before radiosurgery, a CBCT was acquired using the on-board imaging functionality of the Gamma Knife Icon, which provides a registration of the patient's anatomy to stereotactic space independent of that provided by the stereotactic frame/fiducials. Co-registration of the CT and CBCT provides an estimate of the difference between these two estimates of stereotactic coordinates. The vector magnitudes of the differences measured at the center of stereotactic space were 0.93mm, 2.64mm and 2.18 mm for Case 1, Case 2 and Case 3 respectively. Conclusions: Use of the CBCT functionality of the Gamma Knife Icon to verify the consistency of frame placement can prevent clinically significant targeting errors due to frame slippage or frame adapter mounting errors, and allows any required adjustments to be made without interrupting the overall treatment workflow. [ABSTRACT FROM AUTHOR]
- Published
- 2018
40. Spatial shifts in frame-based Gamma Knife radiosurgery: A case for cone beam CT imaging as quality assurance using the Gamma Knife® Icon™.
- Author
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Peach MS, Trifiletti DM, Dutta SW, Larner JM, Schlesinger DJ, and Sheehan JP
- Abstract
Background: Cone beam CT (CBCT) imaging has been integrated into the most recent version of the Leksell Gamma Knife for the primary purpose to facilitate fractionated therapy., Case Description: This case study presents three patients where the CBCT system of the Gamma Knife Icon discovered potentially clinically significant frame shifts. In each case, patients were imaged with volumetric MR prior to stereotactic frame placement. Immediately following frame placement, diagnostic stereotactic CT imaging was acquired with a stereotactic indicator box attached to the frame. Following treatment planning and immediately before radiosurgery, a CBCT was acquired using the on-board imaging functionality of the Gamma Knife Icon, which provides a registration of the patient's anatomy to stereotactic space independent of that provided by the stereotactic frame/fiducials. Co-registration of the CT and CBCT provides an estimate of the difference between these two estimates of stereotactic coordinates. The vector magnitudes of the differences measured at the center of stereotactic space were 0.93mm, 2.64mm and 2.18 mm for Case 1, Case 2 and Case 3 respectively., Conclusions: Use of the CBCT functionality of the Gamma Knife Icon to verify the consistency of frame placement can prevent clinically significant targeting errors due to frame slippage or frame adapter mounting errors, and allows any required adjustments to be made without interrupting the overall treatment workflow., Competing Interests: Authors’ disclosure of potential conflicts of interest Dr. Schlesinger reports grant from Elekta Instrument, AB, outside the submitted work. Dr. Trifiletti reports other support from Novocure, outside the submitted work. Drs. Dutta, Larner, Peach and Sheehan have nothing to disclose.
- Published
- 2018
41. Gamma Knife surgery for brain metastases from gastrointestinal cancer.
- Author
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Da Silva AN, Nagayama K, Schlesinger DJ, and Sheehan JP
- Subjects
- Adult, Aged, Brain Neoplasms mortality, Colonic Neoplasms pathology, Esophageal Neoplasms pathology, Female, Humans, Male, Middle Aged, Pancreatic Neoplasms pathology, Rectal Neoplasms pathology, Retrospective Studies, Stomach Neoplasms pathology, Brain Neoplasms secondary, Brain Neoplasms surgery, Gastrointestinal Neoplasms pathology, Radiosurgery
- Abstract
Object: Brain metastases from gastrointestinal cancers are rare. However, the incidence is increasing because patients with gastrointestinal carcinoma tend to live longer due to earlier diagnosis and more effective treatment of systemic disease. The purpose of this study was to evaluate the efficacy of Gamma Knife surgery (GKS) for the treatment of brain metastases from gastrointestinal cancers., Methods: The authors performed a retrospective review of 40 patients (18 women and 22 men) who had undergone GKS to treat a total of 118 metastases from gastrointestinal cancers between January 1996 and December 2006. The mean patient age was 58.7 years, and the mean Karnofsky Performance Scale (KPS) score was 70. There were 7 patients with esophageal cancer, 25 with colon cancer, 5 with rectal cancer, 2 with pancreatic cancer, and 1 with gastric cancer. Nineteen patients were treated with whole-brain radiotherapy and/or local brain radiotherapy before GKS. Twenty-four patients had extracranial metastases, and 3 had an additional primary cancer. The mean metastatic brain tumor volume was 4.3 cm3, and the mean maximum tumor dose varied from 17.1 to 76.7 Gy (mean 41.8 Gy)., Results: Follow-up imaging studies were available in 25 patients with a total of 90 treated metastases. The results demonstrate a tumor control rate of 91%. The median survival time was 6.7 months, and the 6-month and 1-year survival rates were 55 and 25%, respectively. A univariate analysis revealed that the KPS score (
or=80) was significant (p=0.018) for improved survival., Conclusions: Results in this series suggest that GKS can be an effective tool for the treatment of brain metastases from gastrointestinal cancer. - Published
- 2009
- Full Text
- View/download PDF
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