640 results on '"Sasson S"'
Search Results
2. Identification of neutralising pembrolizumab anti-drug antibodies in patients with melanoma
- Author
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Sasson, S. C., Wilkins, L. E., Watson, R. A., Jolly, C., Brain, O., Klenerman, P., Olsson-Brown, A., and Fairfax, B. P.
- Published
- 2021
- Full Text
- View/download PDF
3. Local heroes or villains: tissue-resident memory T cells in human health and disease
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Sasson, S. C., Gordon, C. L., Christo, S. N., Klenerman, P., and Mackay, L. K.
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- 2020
- Full Text
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4. Secondary spread of Clavibacter michiganensis subsp. michiganensis in nurseries and the conditions leading to infection of tomato seedlings
- Author
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Frenkel, O., Bornestein, M., Shulhani, R., Sharabani, G., Sofer, M., Abo-Moch, F., Lofthouse, M., Manulis-Sasson, S., and Shtienberg, D.
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- 2016
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5. PB2087: EFFICACY OF A 3RD COVID VACCINE, INCLUDING DURING A BTKI PAUSE, IN INDIVIDUALS WITH WALDENSTRÖM MACROGLOBULINEMIA AND FOLLICULAR LYMPHOMA
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Rankin, K., primary, Beaton, B., additional, Sasson, S., additional, Raedemaecker, J., additional, Wong, A., additional, Hastak, P., additional, Phetsouphanh, C., additional, Warden, A., additional, Patel, M., additional, Klemm, V., additional, Munier, C. M. L., additional, Carey Hoppe, A., additional, Tea, F., additional, Pillay, A., additional, Ospina, A., additional, Aggarwal, A., additional, Lavee, O., additional, Caterson, I. D., additional, Turville, S., additional, Kelleher, A. D., additional, Brilot, F., additional, and Trotman, J., additional
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- 2022
- Full Text
- View/download PDF
6. Generation and Characterization of Memory Cd4 T Cells
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Ben-Sasson, S. Z., Zukovsky, Irena, Biton, Aliza, Vogel, Ron, Foucras, Gilles, Hayashi, Nobuki, Paul, William E., Gupta, Sudhir, editor, Butcher, Eugene, editor, and Paul, William, editor
- Published
- 2002
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7. IL-4 is a Major Determinant of T Cell Lymphokine-Producing Phenotype
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Paul, William E., Seder, Robert A., Hu-Ii, Jane, Tanaka, Toshio, Ben-Sasson, S. Z., Gergely, János, editor, Benczúr, M., editor, Erdei, Anna, editor, Falus, A., editor, Füst, Gy., editor, Medgyesi, G., editor, Petrányi, Gy., editor, and Rajnavölgyi, Éva, editor
- Published
- 1993
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- View/download PDF
8. Effect of Plant Systemic Resistance Elicited by Biological and Chemical Inducers on the Colonization of the Lettuce and Basil Leaf Apoplast by Salmonella enterica
- Author
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Chalupowicz, L., primary, Manulis-Sasson, S., additional, Barash, I., additional, Elad, Y., additional, Rav-David, D., additional, and Brandl, M. T., additional
- Published
- 2021
- Full Text
- View/download PDF
9. Comparison of the Freelite serum free light chain (SFLC) assay with serum and urine electrophoresis/immunofixation and the N Latex FLC assay
- Author
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Sasson, S. C., McGill, K., Wienholt, L., Carr, A., Brown, D. A., Kelleher, A. D., Breit, S. N., and Sewell, W. A.
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- 2015
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10. Monoclonal precursor T-cell infiltrate in recurrent thymoma: a case report
- Author
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Sasson, S. C., Smith, S. A., Qiu, M. R., Stone, E. C. A., and Sewell, W. A.
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- 2015
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11. Cotyledons are the main source of secondary spread of Acidovorax citrulli in melon nurseries
- Author
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Chalupowicz, L., Dror, O., Reuven, M., Burdman, S., and Manulis-Sasson, S.
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- 2015
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12. Investigation of the membrane fluidity regulation of fatty acid intracellular distribution by fluorescence lifetime imaging of novel polarity sensitive fluorescent derivatives
- Author
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Bianchetti, Giada, Azoulay-Ginsburg, S., Keshet-Levy, N. Y., Malka, A., Zilber, S., Korshin, E. E., Sasson, S., De Spirito, Marco, Gruzman, A., Maulucci, Giuseppe, Bianchetti G., De Spirito M. (ORCID:0000-0003-4260-5107), Maulucci G. (ORCID:0000-0002-2154-319X), Bianchetti, Giada, Azoulay-Ginsburg, S., Keshet-Levy, N. Y., Malka, A., Zilber, S., Korshin, E. E., Sasson, S., De Spirito, Marco, Gruzman, A., Maulucci, Giuseppe, Bianchetti G., De Spirito M. (ORCID:0000-0003-4260-5107), and Maulucci G. (ORCID:0000-0002-2154-319X)
- Abstract
Free fatty acids are essential structural components of the cell, and their intracellular distribution and effects on membrane organelles have crucial roles in regulating the metabolism, development, and cell cycle of most cell types. Here we engineered novel fluorescent, polarity-sensitive fatty acid derivatives, with the fatty acid aliphatic chain of increasing length (from 12 to 18 carbons). As in the laurdan probe, the lipophilic acyl tail is connected to the environmentally sensitive dimethylaminonaphthalene moiety. The fluorescence lifetime imaging analysis allowed us to monitor the intracellular distribution of the free fatty acids within the cell, and to simultaneously examine how the fluidity and the microviscosity of the membrane environment influence their localization. Each of these probes can thus be used to investigate the membrane fluidity regulation of the correspondent fatty acid intracellular distribution. We observed that, in PC-12 cells, fluorescent sensitive fatty acid derivatives with increased chain length compartmentalize more preferentially in the fluid regions, characterized by a low microviscosity. Moreover, fatty acid derivatives with the longest chain compartmentalize in lipid droplets and lysosomes with characteristic lifetimes, thus making these probes a promising tool for monitoring lipophagy and related events.
- Published
- 2021
13. Cyclooxygenase-2 (PTGS2) inhibitors augment the rate of hexose transport in L6 myotubes in an insulin- and AMPKα-independent manner
- Author
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Alpert, E., Gruzman, A., Lardi-Studler, B., Cohen, G., Reich, R., and Sasson, S.
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- 2006
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14. Delayed autoregulation of glucose transport in vascular endothelial cells
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Alpert, E., Gruzman, A., Riahi, Y., Blejter, R., Aharoni, P., Weisinger, G., Eckel, J., Kaiser, N., and Sasson, S.
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- 2005
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15. Antidiabetic effect of novel modulating peptides of G-protein-coupled kinase in experimental models of diabetes
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Anis, Y., Leshem, O., Reuveni, H., Wexler, I., Ben Sasson, R., Yahalom, B., Laster, M., Raz, I., Ben Sasson, S., Shafrir, E., and Ziv, E.
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- 2004
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16. Effects of plant age on disease development and virulence of Clavibacter michiganensis subsp. michiganensis on tomato
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Sharabani, G., Shtienberg, D., Borenstein, M., Shulhani, R., Lofthouse, M., Sofer, M., Chalupowicz, L., Barel, V., and Manulis-Sasson, S.
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- 2013
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17. Characterization of Dickeya strains isolated from potato grown under hot-climate conditions
- Author
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(Lahkim), Tsror L., Ben-Daniel, B., Chalupowicz, L., van der Wolf, J., Lebiush, S., Erlich, O., Dror, O., Barel, V., Nijhuis, E., and Manulis-Sasson, S.
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- 2013
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18. Metabolic aging in diabetes: The glucoliptoxic connection
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Cohen, G., Kaiser, N., and Sasson, S.
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- 2013
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19. The significance of guttation in the secondary spread of Clavibacter michiganensis subsp. michiganensis in tomato greenhouses
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Sharabani, G., Manulis-Sasson, S., Borenstein, M., Shulhani, R., Lofthouse, M., Chalupowicz, L., and Shtienberg, D.
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- 2013
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20. Amelioration of TNBS-induced colon inflammation in rats by phospholipase [A.sub.2] inhibitor
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Krimsky, M., Yedgar, S., Aptekar, L., Schwob, O, Goshen, G., Gruzman, A., Sasson, S., and Ligumsky, M.
- Subjects
Colitis -- Research ,Biological sciences - Abstract
The pathophysiology of infiammatory bowel disease (IBD) involves the production of diverse lipid mediators, namely eicosanoids, lysophospholipids, and platelet-activating factor, in which phospholipase [A.sub.2] (PL[A.sub.2]) is the key enzyme. Accordingly, it has been postulated that control of lipid mediator production by inhibition of PL[A.sub.2] would be useful for the treatment of IBD. This hypothesis was tested in the present study by examining the therapeutic effect of a novel extracellular PL[A.sub.2] inhibitor (ExPLI), composed of carboxymethylcellulose-linked phosphatidylethanolamine (CMPE), on trinitrobenzenesulfonic acid-induced colitis. Intraperitoneal administration of CMPE suppressed the colitis as measured by mortality rate, intestinal permeability, plasma PL[A.sub.2] activity, intestinal myeloperoxidase activity, and histological morphometry. Current therapeutic approaches for inflammatory conditions focus on the selective control of a lipid mediator(s) (e.g., prostaglandins or leukotrienes). The present study supports the concept that inclusive control of lipid mediator production by PL[A.sub.2] inhibition is a plausible approach to the treatment of colitis and introduces the ExPLIs as a prototype of a novel NSAID for the treatment of intestinal inflammation. inflammatory bowel disease; colitis; nonsteroidal anti-inflammatory drugs
- Published
- 2003
21. IL-1 acts on T cells to enhance the magnitude of in vivo immune responses
- Author
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Ben-Sasson, S. Z., Caucheteux, Stephane, Crank, Michelle, Hu-Li, Jane, and Paul, William E.
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- 2011
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22. Mucosal-associated invariant T (MAIT) cells are activated in the gastrointestinal tissue of patients with combination ipilimumab and nivolumab therapy-related colitis in a pathology distinct from ulcerative colitis
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Sasson, S C, primary, Zaunders, J J, additional, Nahar, K, additional, Munier, C M L, additional, Fairfax, B P, additional, Olsson-Brown, A, additional, Jolly, C, additional, Read, S A, additional, Ahlenstiel, G, additional, Palendira, U, additional, Scolyer, R A, additional, Carlino, M S, additional, Payne, M J, additional, Cheung, V T F, additional, Gupta, T, additional, Klenerman, P, additional, Long, G V, additional, Brain, O, additional, Menzies, A M, additional, and Kelleher, A D, additional
- Published
- 2020
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23. First Report of Pectobacterium parmentieri, One of the Causal Agents of Potato Blackleg and Tuber Soft Rot Diseases, in Israel
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Tsror (Lahkim), L., primary, Erlich, O., additional, Lebiush, S., additional, Galilov, I., additional, Hazanovsky, M., additional, Chalupowicz, L., additional, Reuven, M., additional, Dror, O., additional, and Manulis-Sasson, S., additional
- Published
- 2020
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24. P272 Immune checkpoint inhibitor-related colitis assessment and prognosis: can inflammatory bowel disease scoring point the way?
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Cheung, V T F, primary, Gupta, T, additional, Olsson-Brown, A, additional, Subramanian, S, additional, Sasson, S C, additional, Heseltine, J, additional, Fryer, E, additional, Collantes, E, additional, Sacco, J J, additional, Pirmohamed, M, additional, Simmons, A, additional, Klenerman, P, additional, Fairfax, B P, additional, Payne, M J, additional, Middleton, M R, additional, and Brain, O, additional
- Published
- 2020
- Full Text
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25. Laparoscopic hysteropexy: the initial results of a uterine suspension procedure for uterovaginal prolapse
- Author
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Sasson, S, Busby, G, and Broome, J
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- 2010
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26. Complications and failure of uterine artery embolisation for intractable postpartum haemorrhage
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Katakam, N, Vitthala, S, Sasson, S, and Williams, A
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- 2009
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27. Substrate autoregulation of glucose transport: hexose 6-phosphate mediates the cellular distribution of glucose transporters
- Author
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Sasson, S., Kaiser, N., Dan-Goor, M., Oron, R., Koren, S., Wertheimer, E., Unluhizarci, K., and Cerasi, E.
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- 1997
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28. Primary lobular carcinoma of the vulva: a case report
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Gopinath, D., Sasson, S., and Nuttall, I. D.
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- 2006
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29. A STUDY OF THE OUTCOME OF FUTURE PREGNANCIES IN WOMEN WITH MASSIVE POSTPARTUM HAEMORRHAGE IN A PREVIOUS PREGNANCY
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Sasson, S, Joshi, S, and Mulik, V
- Published
- 2007
30. Catalyzing transcriptomics research in cardiovascular disease:the CardioRNA COST Action CA17129
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Gomes, C. P. (Clarissa Pedrosa da Costa), Agg, B. (Bence), Andova, A. (Andrejaana), Arslan, S. (Serdal), Baker, A. (Andrew), Bartekova, M. (Monika), Beis, D. (Dimitris), Betsou, F. (Fay), Wettinger, S. B. (Stephanie Bezzina), Bugarski, B. (Branko), Condorelli, G. (Gianluigi), da Silva, G. J. (Gustavo Jose Justo), Danilin, S. (Sabrina), de Gonzalo-Calvo, D. (David), Buil, A. (Alfonso), Carmo-Fonseca, M. (Maria), Enguita, F. J. (Francisco J.), Felekkis, K. (Kyriacos), Ferdinandy, P. (Peter), Gyoengyoesi, M. (Mariann), Hackl, M. (Matthias), Karaduzovic-Hadziabdic, K. (Kanita), Hellemans, J. (Jan), Heymans, S. (Stephane), Hlavackova, M. (Marketa), Hoydal, M. A. (Morten Andre), Jankovic, A. (Aleksandra), Jusic, A. (Amela), Kardassis, D. (Dimitris), Kerkela, R. (Risto), Kuster, G. M. (Gabriela M.), Lakkisto, P. (Paivi), Leszek, P. (Przemyslaw), Lustrek, M. (Mitja), Maegdefessel, L. (Lars), Martelli, F. (Fabio), Novella, S. (Susana), O'Brien, T. (Timothy), Papaneophytou, C. (Christos), Pedrazzini, T. (Thierry), Pinet, F. (Florence), Popescu, O. (Octavian), Potocnjak, I. (Ines), Robinson, E. (Emma), Sasson, S. (Shlomo), Scholz, M. (Markus), Simionescu, M. (Maya), Stoll, M. (Monika), Varga, Z. V. (Zoltan V.), Vinciguerra, M. (Manlio), Xuereb, A. (Angela), Yilmaz, M. B. (Mehmet Birhan), Emanueli, C. (Costanza), Devaux, Y. (Yvan), Gomes, C. P. (Clarissa Pedrosa da Costa), Agg, B. (Bence), Andova, A. (Andrejaana), Arslan, S. (Serdal), Baker, A. (Andrew), Bartekova, M. (Monika), Beis, D. (Dimitris), Betsou, F. (Fay), Wettinger, S. B. (Stephanie Bezzina), Bugarski, B. (Branko), Condorelli, G. (Gianluigi), da Silva, G. J. (Gustavo Jose Justo), Danilin, S. (Sabrina), de Gonzalo-Calvo, D. (David), Buil, A. (Alfonso), Carmo-Fonseca, M. (Maria), Enguita, F. J. (Francisco J.), Felekkis, K. (Kyriacos), Ferdinandy, P. (Peter), Gyoengyoesi, M. (Mariann), Hackl, M. (Matthias), Karaduzovic-Hadziabdic, K. (Kanita), Hellemans, J. (Jan), Heymans, S. (Stephane), Hlavackova, M. (Marketa), Hoydal, M. A. (Morten Andre), Jankovic, A. (Aleksandra), Jusic, A. (Amela), Kardassis, D. (Dimitris), Kerkela, R. (Risto), Kuster, G. M. (Gabriela M.), Lakkisto, P. (Paivi), Leszek, P. (Przemyslaw), Lustrek, M. (Mitja), Maegdefessel, L. (Lars), Martelli, F. (Fabio), Novella, S. (Susana), O'Brien, T. (Timothy), Papaneophytou, C. (Christos), Pedrazzini, T. (Thierry), Pinet, F. (Florence), Popescu, O. (Octavian), Potocnjak, I. (Ines), Robinson, E. (Emma), Sasson, S. (Shlomo), Scholz, M. (Markus), Simionescu, M. (Maya), Stoll, M. (Monika), Varga, Z. V. (Zoltan V.), Vinciguerra, M. (Manlio), Xuereb, A. (Angela), Yilmaz, M. B. (Mehmet Birhan), Emanueli, C. (Costanza), and Devaux, Y. (Yvan)
- Abstract
Cardiovascular disease (CVD) remains the leading cause of death worldwide and, despite continuous advances, better diagnostic and prognostic tools, as well as therapy, are needed. The human transcriptome, which is the set of all RNA produced in a cell, is much more complex than previously thought and the lack of dialogue between researchers and industrials and consensus on guidelines to generate data make it harder to compare and reproduce results. This European Cooperation in Science and Technology (COST) Action aims to accelerate the understanding of transcriptomics in CVD and further the translation of experimental data into usable applications to improve personalized medicine in this field by creating an interdisciplinary network. It aims to provide opportunities for collaboration between stakeholders from complementary backgrounds, allowing the functions of different RNAs and their interactions to be more rapidly deciphered in the cardiovascular context for translation into the clinic, thus fostering personalized medicine and meeting a current public health challenge. Thus, this Action will advance studies on cardiovascular transcriptomics, generate innovative projects, and consolidate the leadership of European research groups in the field. COST (European Cooperation in Science and Technology) is a funding organization for research and innovation networks (www.cost.eu).
- Published
- 2019
31. The combination of whole cell lipidomics analysis and single cell confocal imaging of fluidity and micropolarity provides insight into stress-induced lipid turnover in subcellular organelles of pancreatic beta cells
- Author
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Maulucci, Giuseppe, Cohen, O., Daniel, B., Ferreri, C., Sasson, S., Maulucci G. (ORCID:0000-0002-2154-319X), Maulucci, Giuseppe, Cohen, O., Daniel, B., Ferreri, C., Sasson, S., and Maulucci G. (ORCID:0000-0002-2154-319X)
- Abstract
Modern omics techniques reveal molecular structures and cellular networks of tissues and cells in unprecedented detail. Recent advances in single cell analysis have further revolutionized all disciplines in cellular and molecular biology. These methods have also been employed in current investigations on the structure and function of insulin secreting beta cells under normal and pathological conditions that lead to an impaired glucose tolerance and type 2 diabetes. Proteomic and transcriptomic analyses have pointed to significant alterations in protein expression and function in beta cells exposed to diabetes like conditions (e.g., high glucose and/or saturated fatty acids levels). These nutritional overload stressful conditions are often defined as glucolipotoxic due to the progressive damage they cause to the cells. Our recent studies on the rat insulinoma-derived INS-1E beta cell line point to differential effects of such conditions in the phospholipid bilayers in beta cells. This review focuses on confocal microscopy-based detection of these profound alterations in the plasma membrane and membranes of insulin granules and lipid droplets in single beta cells under such nutritional load conditions.
- Published
- 2019
32. Natural history of fetal hydronephrosis diagnosed on mid-trimester ultrasound
- Author
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SAIRAM, S., AL-HABIB, A., SASSON, S., and THILAGANATHAN, B.
- Published
- 2001
33. Corrigendum to 'European contribution to the study of ROS:A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)' [Redox Biol. 13 (2017) 94-162]
- Author
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Egea, J., Fabregat, I., Frapart, Y. M., Ghezzi, P., Görlach, A., Kietzmann, T., Kubaichuk, K., Knaus, U. G., Lopez, M. G., Olaso-Gonzalez, G., Petry, A., Schulz, R., Vina, J., Winyard, P., Abbas, K., Ademowo, O. S., Afonso, C. B., Andreadou, I., Antelmann, H., Antunes, F., Aslan, M., Bachschmid, M. M., Barbosa, R. M., Belousov, V., Berndt, C., Bernlohr, D., Bertrán, E., Bindoli, A., Bottari, S. P., Brito, P. M., Carrara, G., Casas, A. I., Chatzi, A., Chondrogianni, N., Conrad, M., Cooke, M. S., Costa, J. G., Cuadrado, A., My-Chan Dang, P., De Smet, B., Debelec-Butuner, B., Dias, I. H.K., Dunn, J. D., Edson, A. J., El Assar, M., El-Benna, J., Ferdinandy, P., Fernandes, A. S., Fladmark, K. E., Förstermann, U., Giniatullin, R., Giricz, Z., Görbe, A., Griffiths, H., Hampl, V., Hanf, A., Herget, J., Hernansanz-Agustín, P., Hillion, M., Huang, J., Ilikay, S., Jansen-Dürr, P., Jaquet, V., Joles, J. A., Kalyanaraman, B., Kaminskyy, D., Karbaschi, M., Kleanthous, M., Klotz, L. O., Korac, B., Korkmaz, K. S., Koziel, R., Kračun, D., Krause, K. H., Křen, V., Krieg, T., Laranjinha, J., Lazou, A., Li, H., Martínez-Ruiz, A., Matsui, R., McBean, G. J., Meredith, S. P., Messens, J., Miguel, V., Mikhed, Y., Milisav, I., Milković, L., Miranda-Vizuete, A., Mojović, M., Monsalve, M., Mouthuy, P. A., Mulvey, J., Münzel, T., Muzykantov, V., Nguyen, I. T.N., Oelze, M., Oliveira, N. G., Palmeira, C. M., Papaevgeniou, N., Pavićević, A., Pedre, B., Peyrot, F., Phylactides, M., Pircalabioru, G. G., Pitt, A. R., Poulsen, H. E., Prieto, I., Rigobello, M. P., Robledinos-Antón, N., Rodríguez-Mañas, L., Rolo, A. P., Rousset, F., Ruskovska, T., Saraiva, N., Sasson, S., Schröder, K., Semen, K., Seredenina, T., Shakirzyanova, A., Smith, G. L., Soldati, T., Sousa, B. C., Spickett, C. M., Stancic, A., Stasia, M. J., Steinbrenner, H., Stepanić, V., Steven, S., Tokatlidis, K., Tuncay, E., Turan, B., Ursini, F., Vacek, J., Vajnerova, O., Valentová, K., Van Breusegem, F., Varisli, L., Veal, E. A., Yalçin, A. S., Yelisyeyeva, O., Žarković, N., Zatloukalová, M., Zielonka, J., Touyz, R. M., Papapetropoulos, A., Grune, T., Lamas, S., Schmidt, H. H.H.W., Di Lisa, F., and Daiber, A.
- Published
- 2018
34. Corrigendum to 'European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)' (Redox Biol. (2017) 13 (94–162)(S2213231717303373)(10.1016/j.redox.2017.05.007))
- Author
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Egea, J. Fabregat, I. Frapart, Y.M. Ghezzi, P. Görlach, A. Kietzmann, T. Kubaichuk, K. Knaus, U.G. Lopez, M.G. Olaso-Gonzalez, G. Petry, A. Schulz, R. Vina, J. Winyard, P. Abbas, K. Ademowo, O.S. Afonso, C.B. Andreadou, I. Antelmann, H. Antunes, F. Aslan, M. Bachschmid, M.M. Barbosa, R.M. Belousov, V. Berndt, C. Bernlohr, D. Bertrán, E. Bindoli, A. Bottari, S.P. Brito, P.M. Carrara, G. Casas, A.I. Chatzi, A. Chondrogianni, N. Conrad, M. Cooke, M.S. Costa, J.G. Cuadrado, A. My-Chan Dang, P. De Smet, B. Debelec-Butuner, B. Dias, I.H.K. Dunn, J.D. Edson, A.J. El Assar, M. El-Benna, J. Ferdinandy, P. Fernandes, A.S. Fladmark, K.E. Förstermann, U. Giniatullin, R. Giricz, Z. Görbe, A. Griffiths, H. Hampl, V. Hanf, A. Herget, J. Hernansanz-Agustín, P. Hillion, M. Huang, J. Ilikay, S. Jansen-Dürr, P. Jaquet, V. Joles, J.A. Kalyanaraman, B. Kaminskyy, D. Karbaschi, M. Kleanthous, M. Klotz, L.O. Korac, B. Korkmaz, K.S. Koziel, R. Kračun, D. Krause, K.H. Křen, V. Krieg, T. Laranjinha, J. Lazou, A. Li, H. Martínez-Ruiz, A. Matsui, R. McBean, G.J. Meredith, S.P. Messens, J. Miguel, V. Mikhed, Y. Milisav, I. Milković, L. Miranda-Vizuete, A. Mojović, M. Monsalve, M. Mouthuy, P.A. Mulvey, J. Münzel, T. Muzykantov, V. Nguyen, I.T.N. Oelze, M. Oliveira, N.G. Palmeira, C.M. Papaevgeniou, N. Pavićević, A. Pedre, B. Peyrot, F. Phylactides, M. Pircalabioru, G.G. Pitt, A.R. Poulsen, H.E. Prieto, I. Rigobello, M.P. Robledinos-Antón, N. Rodríguez-Mañas, L. Rolo, A.P. Rousset, F. Ruskovska, T. Saraiva, N. Sasson, S. Schröder, K. Semen, K. Seredenina, T. Shakirzyanova, A. Smith, G.L. Soldati, T. Sousa, B.C. Spickett, C.M. Stancic, A. Stasia, M.J. Steinbrenner, H. Stepanić, V. Steven, S. Tokatlidis, K. Tuncay, E. Turan, B. Ursini, F. Vacek, J. Vajnerova, O. Valentová, K. Van Breusegem, F. Varisli, L. Veal, E.A. Yalçın, A.S. Yelisyeyeva, O. Žarković, N. Zatloukalová, M. Zielonka, J. Touyz, R.M. Papapetropoulos, A. Grune, T. Lamas, S. Schmidt, H.H.H.W. Di Lisa, F. Daiber, A.
- Abstract
The authors regret that they have to correct the acknowledgement of the above mentioned publication as follows: This article/publication is based upon work from COST Action BM1203 (EU-ROS), supported by COST (European Cooperation in Science and Technology) which is funded by the Horizon 2020 Framework Programme of the European Union. COST (European Cooperation in Science and Technology) is a funding agency for research and innovation networks. Our Actions help connect research initiatives across Europe and enable scientists to grow their ideas by sharing them with their peers. This boosts their research, career and innovation. For further information see www.cost.eu. The authors would like to apologise for any inconvenience caused. © 2017 The Author(s)
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- 2018
35. Impact Of Apolipoprotein A1- Or Lecithin:Cholesterol Acyltransferase-Deficiency On White Adipose Tissue Metabolic Activity And Glucose Homeostasis In Mice
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Xepapadaki, E., primary, Maulucci, G., additional, Constantinou, C., additional, Karavia, E.A., additional, Zvintzou, E., additional, Daniel, B., additional, Sasson, S., additional, and Kypreos, K.E., additional
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- 2019
- Full Text
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36. Letters to the Editor
- Author
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Gubbay, Sasson S.
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- 1998
37. Corrigendum to 'European contribution to the study of ROS : A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)' [Redox Biol. 13 (2017) 94-162]
- Author
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Egea, J, Fabregat, I, Frapart, Y M, Ghezzi, P, Görlach, A, Kietzmann, T, Kubaichuk, K, Knaus, U G, Lopez, M G, Olaso-Gonzalez, G, Petry, A, Schulz, R., Vina, J, Winyard, P.J., Abbas, K, Ademowo, O S, Afonso, C B, Andreadou, I, Antelmann, H, Antunes, F, Aslan, M, Bachschmid, M M, Barbosa, M.R.V., Belousov, V, Berndt, C, Bernlohr, D, Bertrán, E, Bindoli, A, Bottari, S P, Brito, P M, Carrara, G, Casas, A I, Chatzi, A, Chondrogianni, N, Conrad, M., Cooke, M S, Gil-da-Costa, Maria J, Cuadrado, A, My-Chan Dang, P, de Smet, M.B.M, Debelec-Butuner, B, Dias, I H K, Dunn, J D, Edson, A J, El Assar, M, El-Benna, J, Ferdinandy, Pter, Fernandes, A S, Fladmark, K E, Förstermann, U, Giniatullin, R, Giricz, Zoltán, Görbe, Anikó, Griffiths, Helen L, Hampl, V, Hanf, A, Herget, J, Hernansanz-Agustín, P, Hillion, M, Huang, J, Ilikay, S, Jansen-Dürr, P, Jaquet, V, Joles, J A, Kalyanaraman, B, Kaminskyy, D, Karbaschi, M, Kleanthous, M, Klotz, L O, Korac, B, Korkmaz, K. S., Koziel, R, Kračun, D, Krause, K H, Křen, V, Krieg, T., Laranjinha, J, Lazou, A, Li, H., Martínez-Ruiz, A, Matsui, R, McBean, G J, Meredith, S P, Messens, J, Miguel, V, Mikhed, Y, Milisav, I, Milković, L, Miranda-Vizuete, A, Mojović, M, Monsalve, M, Mouthuy, P A, Mulvey, J, Münzel, Thomas, Muzykantov, V, Nguyen, I T N, Oelze, M, Oliveira, Nelson Gomes, Palmeira, C M, Papaevgeniou, N, Pavićević, A, Pedre, B, Peyrot, F, Phylactides, M, Pircalabioru, G G, Pitt, A R, Poulsen, H E, Prieto, I, Rigobello, M P, Robledinos-Antón, N, Rodríguez-Mañas, L, Rolo, A P, Rousset, F, Ruskovska, T, Saraiva, N, Sasson, S, Schröder, K, Semen, K, Seredenina, T., Shakirzyanova, A, Smith, Godfrey L, Soldati, T, Sousa, B C, Spickett, C M, Stancic, A, Stasia, M.J., Steinbrenner, H, Stepanić, V, Steven, S, Tokatlidis, K, Tuncay, E, Turan, B, Ursini, F, Vacek, J, Vajnerova, O, Valentová, K, Van Breusegem, F, Varisli, L, Veal, E A, Yalçın, A S, Yelisyeyeva, O, Žarković, N, Zatloukalová, M, Zielonka, J, Touyz, R M, Papapetropoulos, A, Grune, T, Lamas, S, Schmidt, H H H W, Di Lisa, F, Daiber, A, Egea, J, Fabregat, I, Frapart, Y M, Ghezzi, P, Görlach, A, Kietzmann, T, Kubaichuk, K, Knaus, U G, Lopez, M G, Olaso-Gonzalez, G, Petry, A, Schulz, R., Vina, J, Winyard, P.J., Abbas, K, Ademowo, O S, Afonso, C B, Andreadou, I, Antelmann, H, Antunes, F, Aslan, M, Bachschmid, M M, Barbosa, M.R.V., Belousov, V, Berndt, C, Bernlohr, D, Bertrán, E, Bindoli, A, Bottari, S P, Brito, P M, Carrara, G, Casas, A I, Chatzi, A, Chondrogianni, N, Conrad, M., Cooke, M S, Gil-da-Costa, Maria J, Cuadrado, A, My-Chan Dang, P, de Smet, M.B.M, Debelec-Butuner, B, Dias, I H K, Dunn, J D, Edson, A J, El Assar, M, El-Benna, J, Ferdinandy, Pter, Fernandes, A S, Fladmark, K E, Förstermann, U, Giniatullin, R, Giricz, Zoltán, Görbe, Anikó, Griffiths, Helen L, Hampl, V, Hanf, A, Herget, J, Hernansanz-Agustín, P, Hillion, M, Huang, J, Ilikay, S, Jansen-Dürr, P, Jaquet, V, Joles, J A, Kalyanaraman, B, Kaminskyy, D, Karbaschi, M, Kleanthous, M, Klotz, L O, Korac, B, Korkmaz, K. S., Koziel, R, Kračun, D, Krause, K H, Křen, V, Krieg, T., Laranjinha, J, Lazou, A, Li, H., Martínez-Ruiz, A, Matsui, R, McBean, G J, Meredith, S P, Messens, J, Miguel, V, Mikhed, Y, Milisav, I, Milković, L, Miranda-Vizuete, A, Mojović, M, Monsalve, M, Mouthuy, P A, Mulvey, J, Münzel, Thomas, Muzykantov, V, Nguyen, I T N, Oelze, M, Oliveira, Nelson Gomes, Palmeira, C M, Papaevgeniou, N, Pavićević, A, Pedre, B, Peyrot, F, Phylactides, M, Pircalabioru, G G, Pitt, A R, Poulsen, H E, Prieto, I, Rigobello, M P, Robledinos-Antón, N, Rodríguez-Mañas, L, Rolo, A P, Rousset, F, Ruskovska, T, Saraiva, N, Sasson, S, Schröder, K, Semen, K, Seredenina, T., Shakirzyanova, A, Smith, Godfrey L, Soldati, T, Sousa, B C, Spickett, C M, Stancic, A, Stasia, M.J., Steinbrenner, H, Stepanić, V, Steven, S, Tokatlidis, K, Tuncay, E, Turan, B, Ursini, F, Vacek, J, Vajnerova, O, Valentová, K, Van Breusegem, F, Varisli, L, Veal, E A, Yalçın, A S, Yelisyeyeva, O, Žarković, N, Zatloukalová, M, Zielonka, J, Touyz, R M, Papapetropoulos, A, Grune, T, Lamas, S, Schmidt, H H H W, Di Lisa, F, and Daiber, A
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- 2018
38. Corrigendum to 'European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)' [Redox Biol. 13 (2017) 94-162]
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CMM Groep Burgering, MS Nefrologie, Regenerative Medicine and Stem Cells, Circulatory Health, Nefro Vasculaire Geneeskunde, Other research (not in main researchprogram), Egea, J, Fabregat, I, Frapart, Y M, Ghezzi, P, Görlach, A, Kietzmann, T, Kubaichuk, K, Knaus, U G, Lopez, M G, Olaso-Gonzalez, G, Petry, A, Schulz, R., Vina, J, Winyard, P.J., Abbas, K, Ademowo, O S, Afonso, C B, Andreadou, I, Antelmann, H, Antunes, F, Aslan, M, Bachschmid, M M, Barbosa, M.R.V., Belousov, V, Berndt, C, Bernlohr, D, Bertrán, E, Bindoli, A, Bottari, S P, Brito, P M, Carrara, G, Casas, A I, Chatzi, A, Chondrogianni, N, Conrad, M., Cooke, M S, Gil-da-Costa, Maria J, Cuadrado, A, My-Chan Dang, P, de Smet, M.B.M, Debelec-Butuner, B, Dias, I H K, Dunn, J D, Edson, A J, El Assar, M, El-Benna, J, Ferdinandy, Pter, Fernandes, A S, Fladmark, K E, Förstermann, U, Giniatullin, R, Giricz, Zoltán, Görbe, Anikó, Griffiths, Helen L, Hampl, V, Hanf, A, Herget, J, Hernansanz-Agustín, P, Hillion, M, Huang, J, Ilikay, S, Jansen-Dürr, P, Jaquet, V, Joles, J A, Kalyanaraman, B, Kaminskyy, D, Karbaschi, M, Kleanthous, M, Klotz, L O, Korac, B, Korkmaz, K. S., Koziel, R, Kračun, D, Krause, K H, Křen, V, Krieg, T., Laranjinha, J, Lazou, A, Li, H., Martínez-Ruiz, A, Matsui, R, McBean, G J, Meredith, S P, Messens, J, Miguel, V, Mikhed, Y, Milisav, I, Milković, L, Miranda-Vizuete, A, Mojović, M, Monsalve, M, Mouthuy, P A, Mulvey, J, Münzel, Thomas, Muzykantov, V, Nguyen, I T N, Oelze, M, Oliveira, Nelson Gomes, Palmeira, C M, Papaevgeniou, N, Pavićević, A, Pedre, B, Peyrot, F, Phylactides, M, Pircalabioru, G G, Pitt, A R, Poulsen, H E, Prieto, I, Rigobello, M P, Robledinos-Antón, N, Rodríguez-Mañas, L, Rolo, A P, Rousset, F, Ruskovska, T, Saraiva, N, Sasson, S, Schröder, K, Semen, K, Seredenina, T., Shakirzyanova, A, Smith, Godfrey L, Soldati, T, Sousa, B C, Spickett, C M, Stancic, A, Stasia, M.J., Steinbrenner, H, Stepanić, V, Steven, S, Tokatlidis, K, Tuncay, E, Turan, B, Ursini, F, Vacek, J, Vajnerova, O, Valentová, K, Van Breusegem, F, Varisli, L, Veal, E A, Yalçın, A S, Yelisyeyeva, O, Žarković, N, Zatloukalová, M, Zielonka, J, Touyz, R M, Papapetropoulos, A, Grune, T, Lamas, S, Schmidt, H H H W, Di Lisa, F, Daiber, A, CMM Groep Burgering, MS Nefrologie, Regenerative Medicine and Stem Cells, Circulatory Health, Nefro Vasculaire Geneeskunde, Other research (not in main researchprogram), Egea, J, Fabregat, I, Frapart, Y M, Ghezzi, P, Görlach, A, Kietzmann, T, Kubaichuk, K, Knaus, U G, Lopez, M G, Olaso-Gonzalez, G, Petry, A, Schulz, R., Vina, J, Winyard, P.J., Abbas, K, Ademowo, O S, Afonso, C B, Andreadou, I, Antelmann, H, Antunes, F, Aslan, M, Bachschmid, M M, Barbosa, M.R.V., Belousov, V, Berndt, C, Bernlohr, D, Bertrán, E, Bindoli, A, Bottari, S P, Brito, P M, Carrara, G, Casas, A I, Chatzi, A, Chondrogianni, N, Conrad, M., Cooke, M S, Gil-da-Costa, Maria J, Cuadrado, A, My-Chan Dang, P, de Smet, M.B.M, Debelec-Butuner, B, Dias, I H K, Dunn, J D, Edson, A J, El Assar, M, El-Benna, J, Ferdinandy, Pter, Fernandes, A S, Fladmark, K E, Förstermann, U, Giniatullin, R, Giricz, Zoltán, Görbe, Anikó, Griffiths, Helen L, Hampl, V, Hanf, A, Herget, J, Hernansanz-Agustín, P, Hillion, M, Huang, J, Ilikay, S, Jansen-Dürr, P, Jaquet, V, Joles, J A, Kalyanaraman, B, Kaminskyy, D, Karbaschi, M, Kleanthous, M, Klotz, L O, Korac, B, Korkmaz, K. S., Koziel, R, Kračun, D, Krause, K H, Křen, V, Krieg, T., Laranjinha, J, Lazou, A, Li, H., Martínez-Ruiz, A, Matsui, R, McBean, G J, Meredith, S P, Messens, J, Miguel, V, Mikhed, Y, Milisav, I, Milković, L, Miranda-Vizuete, A, Mojović, M, Monsalve, M, Mouthuy, P A, Mulvey, J, Münzel, Thomas, Muzykantov, V, Nguyen, I T N, Oelze, M, Oliveira, Nelson Gomes, Palmeira, C M, Papaevgeniou, N, Pavićević, A, Pedre, B, Peyrot, F, Phylactides, M, Pircalabioru, G G, Pitt, A R, Poulsen, H E, Prieto, I, Rigobello, M P, Robledinos-Antón, N, Rodríguez-Mañas, L, Rolo, A P, Rousset, F, Ruskovska, T, Saraiva, N, Sasson, S, Schröder, K, Semen, K, Seredenina, T., Shakirzyanova, A, Smith, Godfrey L, Soldati, T, Sousa, B C, Spickett, C M, Stancic, A, Stasia, M.J., Steinbrenner, H, Stepanić, V, Steven, S, Tokatlidis, K, Tuncay, E, Turan, B, Ursini, F, Vacek, J, Vajnerova, O, Valentová, K, Van Breusegem, F, Varisli, L, Veal, E A, Yalçın, A S, Yelisyeyeva, O, Žarković, N, Zatloukalová, M, Zielonka, J, Touyz, R M, Papapetropoulos, A, Grune, T, Lamas, S, Schmidt, H H H W, Di Lisa, F, and Daiber, A
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- 2018
39. Impact of allogeneic hematopoietic stem cell transplantation on the HIV reservoir and immune response in three HIV infected individuals
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Koelsch, Kersten K, Rasmussen, T A, Hey-Nguyen, W J, Pearson, C. P., Xu, Y, Bailey, M, Marks, K H, Sasson, S C, Taylor, Martin S., Tantau, R, Obeid, S, Milner, B, Morrissey, C O, Pinto, A N, Suzuki, K, Busch, M P, Keating, S M, Kaiser, P., Yukl, S, Wong, J K, Hiener, B M, Palmer, S, Zaunders, J, Post, Jan Andries, Chan, D J, Avery, S, Milliken, S T, Kelleher, Anthony D, Lewin, Sharon R, and Cooper, D A
- Subjects
surgical procedures, operative ,Journal Article - Abstract
BACKGROUND: Allogeneic hematopoietic stem cell transplantation (HSCT) can lead to significant changes to the HIV reservoir and HIV immune responses, indicating that further characterisation of HIV infected patients undergoing HSCT is warranted.METHODS: We studied three patients who underwent HSCT after either reduced intensity conditioning or myeloablative conditioning regimen. We measured HIV antigens and antibodies (Ag/Ab), HIV specific CD4+ T cell responses, HIV RNA and DNA in plasma, peripheral blood mononuclear cells (PBMCs), isolated CD4+ T cells from peripheral blood and lymph node cells. The patients remained on ART throughout the follow up period.RESULTS: All patients have been in continued remission for 4-6 years post-HSCT. Analyses of HIV RNA and DNA levels showed substantial reductions in HIV reservoir related measurements in all three patients, changes in immune response varied with pronounced reductions in two patients and a less dramatic reduction in one patient. One patient experienced unexpected viral rebound 4 years after HSCT.CONCLUSION: These three cases highlight the substantial changes to the HIV reservoir and the HIV immune response in patients undergoing allogeneic HSCT. The viral rebound observed in one patient indicates that replication competent HIV can re-emerge several years following HSCT despite these marked changes.
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- 2017
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40. Cardiovascular Efficacy and Safety of Bococizumab in High-Risk Patients
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Ridker, P. M., Revkin, J., Amarenco, P., Brunell, R., Civeira, F., Flather, M., Glynn, R. J., Gregoire, J., Jukema, J. W., Karpov, Y., Kastelein, J. J. P., Koenig, W., Lorenzatti, A., Manga, P., Masiukiewicz, U., Miller, M., Mosterd, A., Murin, J., Nicolau, J. C., Nissen, S., Ponikowski, P., Santos, R. D., Schwartz, P. F., Soran, H., White, H., Wright, R. S., Vrablik, M., Yunis, C., Shear, C. L., Tardif, Conde D, J. -C., Colquhoun, D, Missault, L, Grégoire, J, Gao, R, Urina, M, Solar, M, Jensen, Hk, Grobbee, D, Savolainen, M, Schiele, Fn, Montalescot, G, Edes, I, Blake, G, Lotan, C, Maggioni, A, Savonitto, S, Lee, Cw, Leiva Pons JL, Dan, Ga, Cortada, Jb, Mellbin, L, Kahan, T, Noble, S, Hwang, Jj, Sritara, P, Tökgozoğlu, L, Tarasenko, L, Borer, Js, Black, H, Carmena, R, Furie, Kl, Mcmurray, J, Neaton, J, Zannad, F, O’Neill, B, Welty, F, Mcnamara, R, Chun, H, Abbott, Jd, Jacoby, D, Mcpherson, C, Jadbabaie, F, Pinto, D, Mccullough, L, Silverman, Ie, Sansing, Lh, Dearborn-Tomazos, J, Foody, J, Schindler, J, Piazza, G, Chakrabarti, A, Pride, Y, Gelfand, E, Baultrukonis, D, Chaudhuri, S, Frederich, R, Johnson, M, Mridha, K, Powell, C, Wang, E, Wei, C, Anderson, P, Buonanno, M, Epsley, C, Evans, B, Frolova, M, Goetsch, M, Hessinger, D, Ikehara, E, Ivanac, K, Kizko, J, Le, K, McNally-Dufort, C, Morocco, T, Nadkarni, S, Nissen, T, Nye, R, Pak, R, Pence, D, Redifer, P, Schwartz, W, Sattler, C, Schade, R, Sullivan, B, Wegner, J, Alvarez, Ca, Budassi, N, Vogel, Dr, Avaca, H, Conde, Dg, Estol, Cc, Gelersztein, E, Glenny, Ja, Hershson, Ar, Bruno, Rl, Maffei, Le, Soler, Jm, Zaidman, Cj, Carnero, Gs, Colombo, Hr, Jure, Ho, Luquez, Ha, Ramos, Hr, Resk, Jh, Rusculleda, Mm, Ulla, Mr, Caccavo, A, Farias, Ef, Wenetz, Lm, Cabella, Pr, Cuadrado, Ja, Chahin, M, Mackinnon, Ij, Zarandon, Rb, Schmidberg, J, Fernandez, Aa, Montana, O, Codutti, Or, Gorosito, Vm, Maldonado, N, Sala, J, De La Fuente RA, Casabella, Te, Di Gennaro JP, Guerrero, Ra, Alvarez, Ms, Berli, M, Botta, Ce, Montenegro, Ee, Vico, Ml, Begg, A, Lehman, R, Gilfillan, Cp, D'Emden, M, Markovic, Tp, Sullivan, D, Aroney, C, Stranks, Sn, Crimmins, Ds, Arstall, M, Van Gaal, W, Davis, T, Aylward, Pe, Amerena, J, William, M, Proietto, J, Purnell, Pw, Singh, B, Arya, Kw, Dart, Am, Thompson, P, Davis, Sm, Carroll, Pa, De Looze, F, Jayasinghe, R, Bhindi, R, Buysschaert, I, Sarens, T, van de Borne, P, Scott, Bp, Roosen, J, 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Gillespie, E, Bybee, Ka, Moriarty, Pm, Savin, V, Agaiby, Jm, Melucci, Mb, Jantzi, Cm, Davidson, E, Smith, Wb, Treasure, Cb, Wakefield, Ph, Deck, K, Edris, Ma, Gilmore, Rm, Seep, Mk, Andersen, Jl, Detweiler, Ro, Rosenfeld, Jc, Strobl, Dj, Steinhoff, Jp, Adams, A, Estevez, R, Molin, Cj, Kim, Cy, Dy, J, Fox, Ke, Farris, Nr, Wayne, Jd, Whitney, Rt, Randhawa, Pm, Mego, Dm, Macdolnald, L, Caputo, Rp, Rigolosi, R, Vannatta, B, Pacheco, Tr, El-Shahawy, M, Gonzalez, Ej, Guice, Mj, Cherlin, Rs, Bays, He, Shoukfeh, M, Morris, Fh, Loy, J, Vora, Sk, Staab, Pk, Frisoli, A, Kimmel, Ma, Cohen, Aj, Green, Cb, Whitlock, L, Butuk, Dj, Mccartney, Mj, Ables, Lr, Acosta, R, Alvarez, Jg, Barrera, Cm, Benitez, O, Berenguer, Ra, Breton, Cf, Chiong, R, Delgado, Mi, Dufreny, A, Fialkow, Ja, Franczek, S, Frias, Jj, Iglesias, C, Landron-Garcia, L, Llerena, Sn, Martinez, Rf, Miranda, Aa, Morytko, Ja, Rodriguez, Ij, Sotolongo, R, Suarez-Sarmiento, A, Terrelonge, Ae, Vaca, Ce, Venereo, Jm, Verdeza, C, Zeno, Ml, Chilka, S, Felten, Wr, Hartman, An, Shayani, Ss, Duprez, D, Knickelbine, T, Chambers, Jd, Cone, Cl, Broughton, R, Napoli, Mc, Seaton, Bl, Smith, Sk, Reedy, Ma, Kesani, Mk, Nicol, Pr, Stringam, So, Talano, Jv, Barnum, O, Desai, V, Montero, M, Jacks, Rk, Kostis, Jb, Owen, Jg, Makam, Sk, Grosman, I, Underberg, Ja, Masri, Be, Peters, Ss, Serje, J, Lenhard, Mj, Glover, R, Paraboschi, Cf, Lim, Eh, Connery, L, Kipgen, W, Bravo, P, Digiovanna, Mj, Tayoum, H, Gabriel, Jd, Ariani, Mk, Robinson, Mf, Clemens, Pc, Corder, Cn, Schifferdecker, B, Tahirkheli, Nk, Hurling, Rt, Rendell, Ms, Shivaswamy, V, Madu, Ij, Dahl, Cf, Ayesu, K, Kim, C, Barettella, Mb, Jamidar, Ha, Bloom, Sa, Vora, Kn, Ong, St, Aggarwala, G, Sack, G, Blaze, K, Krichmar, P, Murcia, A, Teltser, M, Villaman-Bencosme, Y, Fahdi, Ie, Williams, Dg, Lain, El, Garcia, Hl, Karim, Sn, Francyk, Dm, Gordon, Mb, Palchick, Ba, Mckenzie, Me, Gimness, Mp, Greiff, J, Ruiz-R, L, Vazquez-Tanus, Jb, Schlager, D, Connelly, T, Soroka, E, Hastings, Wl, O’Dea, Dj, Purdy, Da, Jackson, B, Arcanese, Ml, Strain, Je, Schmedtje JF Jr, Jrdavis, Mg, A, A, Prasada, S, Scott, Dl, Vukotic, G, Akhtar, N, Larsen, Dc, Rhudy, Jm, Zebrack, Js, Bailey, Sr, Grant, Dc, Mora, A, Perez, Ja, Reyes, Rg, Sutton, Jc, Brandon, Dm, First, Bp, Risser, Ja, Claudio, J, Figueroa-Cruz, Wl, Sosa-Padilla, Ma, Tan, Ae, Traboulssi, Ma, Morcos, Nc, Glaser, La, Bredlau, Ce, El Shahawy, M, Ramos, Mj, Kandath, Dd, Kaluski, E, Akright, L, Rictor, Kw, Pluto, Tm, Hermany, Pr, Bellingar, B, Clark, Gb, Herrod, Jn, Goisse, M, Hook, M, Barrington, P, Lentz, Jd, Singal, Dk, Gleason, Gp, Lipetz, Rs, Schuchard, Tn, Bonner, Jh, Forgosh, Lb, Lefebvre, Gc, Pierpoint, Be, Radin, Dm, Stoller, Sr, Segall, N, Shah, Sa, Ramstad, Ds, Nisnisan, Jm, Trippett, Jm, Benjamin, Sa, Labissiere, Jc, Nashed, An, Maaieh, M, Aslam, Aa, Mandviwala, M, Budoff, Mj, French, Wj, Vlach, Jj, Destefano, P, Bayron, Cj, Fraser, Nj, Sandberg, Jh, Fagan, Tc, Peart, Bc, Suryanarayana, Pg, Gupta, Dk, Lee, Mw, Bertolet, Bd, Hartley, Pa, Kelberman, M, Behmanesh, B, Buynak, Rj, Chochinov, Rh, Steinberg, Aa, Chandna, H, Bjasker, Kr, Perlman, Rl, Ball, Em, Pock, J, Singh, S, Baldari, D, Kaster, S, Lovell, Jp, Horowitz, Bs, Gorman, Ta, Pham, Dn, Landzberg, Js, Mootoo, Ki, Moon, E, Krawczyk, J, Alfieri, Ad, Janik, Mj, Herrington, Dm, Koilpillai, Rn, Waxler, Ar, Hoffman, Da, Sahul, Zh, Gumbiner, B, Cropp, A, Fujita, K, Garzone, P, Imai, K, Levisetti, M, Plowchalk, D, Sasson, S, Skaggs, J, Sweeney, K, Vincent, J., Curto, M, Ridker, P., Revkin, J., Amarenco, P., Brunell, R., Curto, M., Civeira, F., Flather, M., Glynn, R., Gregoire, J., Jukema, J., Karpov, Y., Kastelein, J., Koenig, W., Lorenzatti, A., Manga, P., Masiukiewicz, U., Miller, M., Mosterd, A., Murin, J., Nicolau, J., Nissen, S., Ponikowski, P., Santos, R., Schwartz, P., Soran, H., White, H., Wright, R., Vrablik, M., Yunis, C., Shear, C., Tardif, J., SPIRE Cardiovascular Outcome Investigators, Averna, M., Brigham and Women's Hospital [Boston], Université Paris Diderot - Paris 7 (UPD7), Université Sorbonne Paris Cité (USPC), RS: CARIM - R3.02 - Hypertension and target organ damage, MUMC+: MA Alg Interne Geneeskunde (9), Interne Geneeskunde, Ridker, P. M., Glynn, R. J., Jukema, J. W., Kastelein, J. J. P., Nicolau, J. C., Santos, R. D., Schwartz, P. F., Wright, R. S., Shear, C. L., Tardif, J. -C., SPIRE Cardiovascular Outcome Investigator, Perrone, Filardi, P, Vascular Medicine, ACS - Amsterdam Cardiovascular Sciences, ACS - Pulmonary hypertension & thrombosis, and ACS - Atherosclerosis & ischemic syndromes
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Male ,STATIN THERAPY ,Anticholesteremic Agents/adverse effects ,Antibodie ,Vascular damage Radboud Institute for Health Sciences [Radboudumc 16] ,Injections, Subcutaneous/adverse effects ,030204 cardiovascular system & hematology ,Bococizumab ,law.invention ,PCSK9 ,0302 clinical medicine ,Randomized controlled trial ,law ,Risk Factors ,GENETIC-VARIANTS ,Cardiovascular Disease ,Monoclonal ,Anticholesteremic Agent ,030212 general & internal medicine ,Myocardial infarction ,Treatment Failure ,Humanized ,Proprotein Convertase 9/antagonists & inhibitors ,Medicine(all) ,Antibodies ,Antibodies, Monoclonal, Humanized ,Anticholesteremic Agents ,Cardiovascular Diseases ,Cholesterol, LDL ,Double-Blind Method ,Female ,Follow-Up Studies ,Humans ,Hypercholesterolemia ,Injections, Subcutaneous ,Lipids ,Middle Aged ,Proprotein Convertase 9 ,Medicine (all) ,PCSK9 Inhibitors ,antibodies monoclonal humanized ,anticholesteremic agents ,cardiovascular diseases ,cholesterol, LDL ,double-blind method ,female ,follow-up studies ,humans ,hypercholesterolemia ,injections, subcutaneous ,lipids ,male ,middle aged ,proprotein convertase 9 ,risk factors ,treatment failure ,medicine (all) ,Vascular damage Radboud Institute for Molecular Life Sciences [Radboudumc 16] ,General Medicine ,Lipid ,3. Good health ,LDL/blood ,Multicenter Study ,Cholesterol ,TRIALS ,Cholesterol, LDL/blood ,Antibodies, Monoclonal, Humanized/adverse effects ,Randomized Controlled Trial ,subcutaneous ,lipids (amino acids, peptides, and proteins) ,Cardiovascular Diseases/prevention & control ,REDUCING LIPIDS ,Human ,medicine.medical_specialty ,animal structures ,Hypercholesterolemia/drug therapy ,Placebo ,Injections, Subcutaneou ,LDL ,Injections ,Follow-Up Studie ,EVENTS ,03 medical and health sciences ,Internal medicine ,medicine ,Journal Article ,Comparative Study ,METAANALYSIS ,Alirocumab ,business.industry ,Unstable angina ,Lipids/blood ,Risk Factor ,fungi ,Antibodies/blood ,ta3121 ,medicine.disease ,Surgery ,Evolocumab ,REDUCTION ,Humanized/adverse effects ,Subcutaneous/adverse effects ,business ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology - Abstract
Item does not contain fulltext BACKGROUND: Bococizumab is a humanized monoclonal antibody that inhibits proprotein convertase subtilisin-kexin type 9 (PCSK9) and reduces levels of low-density lipoprotein (LDL) cholesterol. We sought to evaluate the efficacy of bococizumab in patients at high cardiovascular risk. METHODS: In two parallel, multinational trials with different entry criteria for LDL cholesterol levels, we randomly assigned the 27,438 patients in the combined trials to receive bococizumab (at a dose of 150 mg) subcutaneously every 2 weeks or placebo. The primary end point was nonfatal myocardial infarction, nonfatal stroke, hospitalization for unstable angina requiring urgent revascularization, or cardiovascular death; 93% of the patients were receiving statin therapy at baseline. The trials were stopped early after the sponsor elected to discontinue the development of bococizumab owing in part to the development of high rates of antidrug antibodies, as seen in data from other studies in the program. The median follow-up was 10 months. RESULTS: At 14 weeks, patients in the combined trials had a mean change from baseline in LDL cholesterol levels of -56.0% in the bococizumab group and +2.9% in the placebo group, for a between-group difference of -59.0 percentage points (P/=70 mg per deciliter [1.8 mmol per liter] and the median follow-up was 7 months), major cardiovascular events occurred in 173 patients each in the bococizumab group and the placebo group (hazard ratio, 0.99; 95% confidence interval [CI], 0.80 to 1.22; P=0.94). In the higher-risk, longer-duration trial (in which the patients had a baseline LDL cholesterol level of >/=100 mg per deciliter [2.6 mmol per liter] and the median follow-up was 12 months), major cardiovascular events occurred in 179 and 224 patients, respectively (hazard ratio, 0.79; 95% CI, 0.65 to 0.97; P=0.02). The hazard ratio for the primary end point in the combined trials was 0.88 (95% CI, 0.76 to 1.02; P=0.08). Injection-site reactions were more common in the bococizumab group than in the placebo group (10.4% vs. 1.3%, P
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41. Diagnosis of plant diseases using the Nanopore sequencing platform
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Chalupowicz, L., primary, Dombrovsky, A., additional, Gaba, V., additional, Luria, N., additional, Reuven, M., additional, Beerman, A., additional, Lachman, O., additional, Dror, O., additional, Nissan, G., additional, and Manulis‐Sasson, S., additional
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- 2018
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42. Bacterial canker severity during the nursery stage is affected by fertigation
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Frenkel, O., primary, Chalupowicz, L., additional, Shulhani, R., additional, Bornstein, M., additional, Abu-Moch, F., additional, Sofer, M., additional, Manulis‑Sasson, S., additional, and Shtienberg, D., additional
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- 2018
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43. The prevalence, aggressiveness and survival of Clavibacter michiganensis subsp. michiganensis strains associated with different genetic groups in Israel
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Shtienberg, D., primary, Frenkel, O., additional, Rekah, Y., additional, Dror, O., additional, Abu-Moch, F., additional, and Manulis-Sasson, S., additional
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- 2018
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44. Differences between the olive fruit and leaf abscission zones enable development of a selective abscission compound
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Cohen, S., primary, Burstein, C., additional, Biton, I., additional, Ben Sasson, S., additional, Sade, A., additional, Mani, Y., additional, Doron-Faigenboim, A., additional, Zemach, H., additional, Mugira, Y., additional, Schneider, D., additional, Birger, R., additional, Meir, S., additional, Philosoph-Hadas, S., additional, Irihomovitch, V., additional, Lavee, S., additional, Avidan, B., additional, and Ben-Ari, G., additional
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- 2018
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45. Corrigendum to “European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)” [Redox Biol. 13 (2017) 94–162]
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Egea, J., primary, Fabregat, I., additional, Frapart, Y.M., additional, Ghezzi, P., additional, Görlach, A., additional, Kietzmann, T., additional, Kubaichuk, K., additional, Knaus, U.G., additional, Lopez, M.G., additional, Olaso-Gonzalez, G., additional, Petry, A., additional, Schulz, R., additional, Vina, J., additional, Winyard, P., additional, Abbas, K., additional, Ademowo, O.S., additional, Afonso, C.B., additional, Andreadou, I., additional, Antelmann, H., additional, Antunes, F., additional, Aslan, M., additional, Bachschmid, M.M., additional, Barbosa, R.M., additional, Belousov, V., additional, Berndt, C., additional, Bernlohr, D., additional, Bertrán, E., additional, Bindoli, A., additional, Bottari, S.P., additional, Brito, P.M., additional, Carrara, G., additional, Casas, A.I., additional, Chatzi, A., additional, Chondrogianni, N., additional, Conrad, M., additional, Cooke, M.S., additional, Costa, J.G., additional, Cuadrado, A., additional, My-Chan Dang, P., additional, De Smet, B., additional, Debelec-Butuner, B., additional, Dias, I.H.K., additional, Dunn, J.D., additional, Edson, A.J., additional, El Assar, M., additional, El-Benna, J., additional, Ferdinandy, P., additional, Fernandes, A.S., additional, Fladmark, K.E., additional, Förstermann, U., additional, Giniatullin, R., additional, Giricz, Z., additional, Görbe, A., additional, Griffiths, H., additional, Hampl, V., additional, Hanf, A., additional, Herget, J., additional, Hernansanz-Agustín, P., additional, Hillion, M., additional, Huang, J., additional, Ilikay, S., additional, Jansen-Dürr, P., additional, Jaquet, V., additional, Joles, J.A., additional, Kalyanaraman, B., additional, Kaminskyy, D., additional, Karbaschi, M., additional, Kleanthous, M., additional, Klotz, L.O., additional, Korac, B., additional, Korkmaz, K.S., additional, Koziel, R., additional, Kračun, D., additional, Krause, K.H., additional, Křen, V., additional, Krieg, T., additional, Laranjinha, J., additional, Lazou, A., additional, Li, H., additional, Martínez-Ruiz, A., additional, Matsui, R., additional, McBean, G.J., additional, Meredith, S.P., additional, Messens, J., additional, Miguel, V., additional, Mikhed, Y., additional, Milisav, I., additional, Milković, L., additional, Miranda-Vizuete, A., additional, Mojović, M., additional, Monsalve, M., additional, Mouthuy, P.A., additional, Mulvey, J., additional, Münzel, T., additional, Muzykantov, V., additional, Nguyen, I.T.N., additional, Oelze, M., additional, Oliveira, N.G., additional, Palmeira, C.M., additional, Papaevgeniou, N., additional, Pavićević, A., additional, Pedre, B., additional, Peyrot, F., additional, Phylactides, M., additional, Pircalabioru, G.G., additional, Pitt, A.R., additional, Poulsen, H.E., additional, Prieto, I., additional, Rigobello, M.P., additional, Robledinos-Antón, N., additional, Rodríguez-Mañas, L., additional, Rolo, A.P., additional, Rousset, F., additional, Ruskovska, T., additional, Saraiva, N., additional, Sasson, S., additional, Schröder, K., additional, Semen, K., additional, Seredenina, T., additional, Shakirzyanova, A., additional, Smith, G.L., additional, Soldati, T., additional, Sousa, B.C., additional, Spickett, C.M., additional, Stancic, A., additional, Stasia, M.J., additional, Steinbrenner, H., additional, Stepanić, V., additional, Steven, S., additional, Tokatlidis, K., additional, Tuncay, E., additional, Turan, B., additional, Ursini, F., additional, Vacek, J., additional, Vajnerova, O., additional, Valentová, K., additional, Van Breusegem, F., additional, Varisli, L., additional, Veal, E.A., additional, Yalçın, A.S., additional, Yelisyeyeva, O., additional, Žarković, N., additional, Zatloukalová, M., additional, Zielonka, J., additional, Touyz, R.M., additional, Papapetropoulos, A., additional, Grune, T., additional, Lamas, S., additional, Schmidt, H.H.H.W., additional, Di Lisa, F., additional, and Daiber, A., additional
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- 2018
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46. Tetracycline And Benign Intracranial Hypertension: Report Of Five Cases
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Walters, Barry N. J. and Gubbay, Sasson S.
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- 1981
47. European contribution to the study of ROS:a summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)
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Egea, J. (Javier), Fabregat, I. (Isabel), Frapart, Y. M. (Yves M.), Ghezzi, P. (Pietro), Görlach, A. (Agnes), Kietzmann, T. (Thomas), Kubaichuk, K. (Kateryna), Knaus, U. G. (Ulla G.), Lopez, M. G. (Manuela G.), Olaso-Gonzalez, G. (Gloria), Petry, A. (Andreas), Schulz, R. (Rainer), Vina, J. (Jose), Winyard, P. (Paul), Abbas, K. (Kahina), Ademowo, O. S. (Opeyemi S.), Afonso, C. B. (Catarina B.), Andreadou, I. (Ioanna), Antelmann, H. (Haike), Antunes, F. (Fernando), Aslan, M. (Mutay), Bachschmid, M. M. (Markus M.), Barbosa, R. M. (Rui M.), Belousov, V. (Vsevolod), Berndt, C. (Carsten), Bernlohr, D. (David), Bertrán, E. (Esther), Bindoli, A. (Alberto), Bottari, S. P. (Serge P.), Brito, P. M. (Paula M.), Carrara, G. (Guia), Casas, A. I. (Ana I.), Chatzi, A. (Afroditi), Chondrogianni, N. (Niki), Conrad, M. (Marcus), Cooke, M. S. (Marcus S.), Costa, J. G. (João G.), Cuadrado, A. (Antonio), My-Chan Dang, P. (Pham), De Smet, B. (Barbara), Debelec-Butuner, B. (Bilge), Dias, I. H. (Irundika H. K.), Dunn, J. D. (Joe D.an), Edson, A. J. (Amanda J.), El Assar, M. (Mariam), El-Benna, J. (Jamel), Ferdinandy, P. (Péter), Fernandes, A. S. (Ana S.), Fladmark, K. E. (Kari E.), Förstermann, U. (Ulrich), Giniatullin, R. (Rashid), Giricz, Z. (Zoltán), Görbe, A. (Anikó), Griffiths, H. (Helen), Hampl, V. (Vaclav), Hanf, A. (Alina), Herget, J. (Jan), Hernansanz-Agustín, P. (Pablo), Hillion, M. (Melanie), Huang, J. (Jingjing), Ilikay, S. (Serap), Jansen-Dürr, P. (Pidder), Jaquet, V. (Vincent), Joles, J. A. (Jaap A.), Kalyanaraman, B. (Balaraman), Kaminskyy, D. (Danylo), Karbaschi, M. (Mahsa), Kleanthous, M. (Marina), Klotz, L.-O. (Lars-Oliver), Korac, B. (Bato), Korkmaz, K. S. (Kemal S.ami), Koziel, R. (Rafal), Kračun, D. (Damir), Krause, K.-H. (Karl-Heinz), Křen, V. (Vladimír), Krieg, T. (Thomas), Laranjinha, J. (João), Lazou, A. (Antigone), Li, H. (Huige), Martínez-Ruiz, A. (Antonio), Matsui, R. (Reiko), McBean, G. J. (Gethin J.), Meredith, S. P. (Stuart P.), Messens, J. (Joris), Miguel, V. (Verónica), Mikhed, Y. (Yuliya), Milisav, I. (Irina), Milković, L. (Lidija), Miranda-Vizuete, A. (Antonio), Mojović, M. (Miloš), Monsalve, M. (María), Mouthuy, P.-A. (Pierre-Alexis), Mulvey, J. (John), Münzel, T. (Thomas), Muzykantov, V. (Vladimir), Nguyen, I. T. (Isabel T. N.), Oelze, M. (Matthias), Oliveira, N. G. (Nuno G.), Palmeira, C. M. (Carlos M.), Papaevgeniou, N. (Nikoletta), Pavićević, A. (Aleksandra), Pedre, B. (Brandán), Peyrot, F. (Fabienne), Phylactides, M. (Marios), Pircalabioru, G. G. (Gratiela G.), Pitt, A. R. (Andrew R.), Poulsen, H. E. (Henrik E.), Prieto, I. (Ignacio), Rigobello, M. P. (Maria P.ia), Robledinos-Antón, N. (Natalia), Rodríguez-Mañas, L. (Leocadio), Rolo, A. P. (Anabela P.), Rousset, F. (Francis), Ruskovska, T. (Tatjana), Saraiva, N. (Nuno), Sasson, S. (Shlomo), Schröder, K. (Katrin), Semen, K. (Khrystyna), Seredenina, T. (Tamara), Shakirzyanova, A. (Anastasia), Smith, G. L. (Geoffrey L.), Soldati, T. (Thierry), Sousa, B. C. (Bebiana C.), Spickett, C. M. (Corinne M.), Stancic, A. (Ana), Stasia, M. J. (Marie J.osé), Steinbrenner, H. (Holger), Stepanić, V. (Višnja), Steven, S. (Sebastian), Tokatlidis, K. (Kostas), Tuncay, E. (Erkan), Turan, B. (Belma), Ursini, F. (Fulvio), Vacek, J. (Jan), Vajnerova, O. (Olga), Valentová, K. (Kateřina), Van Breusegem, F. (Frank), Varisli, L. (Lokman), Veal, E. A. (Elizabeth A.), Yalçın, A. S. (A S.uha), Yelisyeyeva, O. (Olha), Žarković, N. (Neven), Zatloukalová, M. (Martina), Zielonka, J. (Jacek), Touyz, R. M. (Rhian M.), Papapetropoulos, A. (Andreas), Grune, T. (Tilman), Lamas, S. (Santiago), Schmidt, H. H. (Harald H. H. W.), Di Lisa, F. (Fabio), Daiber, A. (Andreas), Egea, J. (Javier), Fabregat, I. (Isabel), Frapart, Y. M. (Yves M.), Ghezzi, P. (Pietro), Görlach, A. (Agnes), Kietzmann, T. (Thomas), Kubaichuk, K. (Kateryna), Knaus, U. G. (Ulla G.), Lopez, M. G. (Manuela G.), Olaso-Gonzalez, G. (Gloria), Petry, A. (Andreas), Schulz, R. (Rainer), Vina, J. (Jose), Winyard, P. (Paul), Abbas, K. (Kahina), Ademowo, O. S. (Opeyemi S.), Afonso, C. B. (Catarina B.), Andreadou, I. (Ioanna), Antelmann, H. (Haike), Antunes, F. (Fernando), Aslan, M. (Mutay), Bachschmid, M. M. (Markus M.), Barbosa, R. M. (Rui M.), Belousov, V. (Vsevolod), Berndt, C. (Carsten), Bernlohr, D. (David), Bertrán, E. (Esther), Bindoli, A. (Alberto), Bottari, S. P. (Serge P.), Brito, P. M. (Paula M.), Carrara, G. (Guia), Casas, A. I. (Ana I.), Chatzi, A. (Afroditi), Chondrogianni, N. (Niki), Conrad, M. (Marcus), Cooke, M. S. (Marcus S.), Costa, J. G. (João G.), Cuadrado, A. (Antonio), My-Chan Dang, P. (Pham), De Smet, B. (Barbara), Debelec-Butuner, B. (Bilge), Dias, I. H. (Irundika H. K.), Dunn, J. D. (Joe D.an), Edson, A. J. (Amanda J.), El Assar, M. (Mariam), El-Benna, J. (Jamel), Ferdinandy, P. (Péter), Fernandes, A. S. (Ana S.), Fladmark, K. E. (Kari E.), Förstermann, U. (Ulrich), Giniatullin, R. (Rashid), Giricz, Z. (Zoltán), Görbe, A. (Anikó), Griffiths, H. (Helen), Hampl, V. (Vaclav), Hanf, A. (Alina), Herget, J. (Jan), Hernansanz-Agustín, P. (Pablo), Hillion, M. (Melanie), Huang, J. (Jingjing), Ilikay, S. (Serap), Jansen-Dürr, P. (Pidder), Jaquet, V. (Vincent), Joles, J. A. (Jaap A.), Kalyanaraman, B. (Balaraman), Kaminskyy, D. (Danylo), Karbaschi, M. (Mahsa), Kleanthous, M. (Marina), Klotz, L.-O. (Lars-Oliver), Korac, B. (Bato), Korkmaz, K. S. (Kemal S.ami), Koziel, R. (Rafal), Kračun, D. (Damir), Krause, K.-H. (Karl-Heinz), Křen, V. (Vladimír), Krieg, T. (Thomas), Laranjinha, J. (João), Lazou, A. (Antigone), Li, H. (Huige), Martínez-Ruiz, A. (Antonio), Matsui, R. (Reiko), McBean, G. J. (Gethin J.), Meredith, S. P. (Stuart P.), Messens, J. (Joris), Miguel, V. (Verónica), Mikhed, Y. (Yuliya), Milisav, I. (Irina), Milković, L. (Lidija), Miranda-Vizuete, A. (Antonio), Mojović, M. (Miloš), Monsalve, M. (María), Mouthuy, P.-A. (Pierre-Alexis), Mulvey, J. (John), Münzel, T. (Thomas), Muzykantov, V. (Vladimir), Nguyen, I. T. (Isabel T. N.), Oelze, M. (Matthias), Oliveira, N. G. (Nuno G.), Palmeira, C. M. (Carlos M.), Papaevgeniou, N. (Nikoletta), Pavićević, A. (Aleksandra), Pedre, B. (Brandán), Peyrot, F. (Fabienne), Phylactides, M. (Marios), Pircalabioru, G. G. (Gratiela G.), Pitt, A. R. (Andrew R.), Poulsen, H. E. (Henrik E.), Prieto, I. (Ignacio), Rigobello, M. P. (Maria P.ia), Robledinos-Antón, N. (Natalia), Rodríguez-Mañas, L. (Leocadio), Rolo, A. P. (Anabela P.), Rousset, F. (Francis), Ruskovska, T. (Tatjana), Saraiva, N. (Nuno), Sasson, S. (Shlomo), Schröder, K. (Katrin), Semen, K. (Khrystyna), Seredenina, T. (Tamara), Shakirzyanova, A. (Anastasia), Smith, G. L. (Geoffrey L.), Soldati, T. (Thierry), Sousa, B. C. (Bebiana C.), Spickett, C. M. (Corinne M.), Stancic, A. (Ana), Stasia, M. J. (Marie J.osé), Steinbrenner, H. (Holger), Stepanić, V. (Višnja), Steven, S. (Sebastian), Tokatlidis, K. (Kostas), Tuncay, E. (Erkan), Turan, B. (Belma), Ursini, F. (Fulvio), Vacek, J. (Jan), Vajnerova, O. (Olga), Valentová, K. (Kateřina), Van Breusegem, F. (Frank), Varisli, L. (Lokman), Veal, E. A. (Elizabeth A.), Yalçın, A. S. (A S.uha), Yelisyeyeva, O. (Olha), Žarković, N. (Neven), Zatloukalová, M. (Martina), Zielonka, J. (Jacek), Touyz, R. M. (Rhian M.), Papapetropoulos, A. (Andreas), Grune, T. (Tilman), Lamas, S. (Santiago), Schmidt, H. H. (Harald H. H. W.), Di Lisa, F. (Fabio), and Daiber, A. (Andreas)
- Abstract
The European Cooperation in Science and Technology (COST) provides an ideal framework to establish multi-disciplinary research networks. COST Action BM1203 (EU-ROS) represents a consortium of researchers from different disciplines who are dedicated to providing new insights and tools for better understanding redox biology and medicine and, in the long run, to finding new therapeutic strategies to target dysregulated redox processes in various diseases. This report highlights the major achievements of EU-ROS as well as research updates and new perspectives arising from its members. The EU-ROS consortium comprised more than 140 active members who worked together for four years on the topics briefly described below. The formation of reactive oxygen and nitrogen species (RONS) is an established hallmark of our aerobic environment and metabolism but RONS also act as messengers via redox regulation of essential cellular processes. The fact that many diseases have been found to be associated with oxidative stress established the theory of oxidative stress as a trigger of diseases that can be corrected by antioxidant therapy. However, while experimental studies support this thesis, clinical studies still generate controversial results, due to complex pathophysiology of oxidative stress in humans. For future improvement of antioxidant therapy and better understanding of redox-associated disease progression detailed knowledge on the sources and targets of RONS formation and discrimination of their detrimental or beneficial roles is required. In order to advance this important area of biology and medicine, highly synergistic approaches combining a variety of diverse and contrasting disciplines are needed.
- Published
- 2017
48. Electrical Sizing of Cells in Suspension
- Author
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Grover, N. B., Ben-Sasson, S. A., Naaman, J., and Catsimpoolas, Nicholas, editor
- Published
- 1982
- Full Text
- View/download PDF
49. Cardiac magnetic resonance imaging-indeterminate/negative cardiac sarcoidosis revealed by 18F-fluorodeoxyglucose-positron emission tomography: two case reports and a review of the literature
- Author
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Sasson, S. C., primary, Russo, R., additional, Chung, T., additional, Chu, G., additional, Hunyor, I., additional, Williamson, J., additional, Murad, A., additional, Kane, A., additional, Riminton, S., additional, and Limaye, S., additional
- Published
- 2017
- Full Text
- View/download PDF
50. Ethephon induced oxidative stress in the olive leaf abscission zone enables development of a selective abscission compound
- Author
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Goldental-Cohen, S., primary, Burstein, C., additional, Biton, I., additional, Ben Sasson, S., additional, Sadeh, A., additional, Many, Y., additional, Doron-Faigenboim, A., additional, Zemach, H., additional, Mugira, Y., additional, Schneider, D., additional, Birger, R., additional, Meir, S., additional, Philosoph-Hadas, S., additional, Irihomovitch, V., additional, Lavee, S., additional, Avidan, B., additional, and Ben-Ari, G., additional
- Published
- 2017
- Full Text
- View/download PDF
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