88 results on '"Salvatori FM"'
Search Results
2. Superior mesenteric artery ischemia: endovascular approach
- Author
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Redler A, Venturini L, Giordano R, Frezzotti F, Pelle F, Giannotti D, Di Rocco G, Fiengo L, Fazi M, Patrizi G, and Salvatori FM
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Geriatrics ,RC952-954.6 - Published
- 2011
- Full Text
- View/download PDF
3. Transplantation of human fetal biliary tree stem/progenitor cells into two patients with advanced liver cirrhosis
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Cardinale, V, Carpino, G, Gentile, R, Napoletano, C, Rahimi, H, Franchitto, Antonio, Semeraro, R, Nuti, M, Onori, Paolo, Berloco, Pasquale Bartolomeo, Rossi, M, Bosco, D, Brunelli, R, Fraveto, A, Napoli, C, Torrice, A, Gatto, M, Venere, R, Bastianelli, C, Aliberti, C, Salvatori, Fm, Attili, Af, Reid, Lm, Gaudio, Eugenio, and Alvaro, D.
- Published
- 2014
4. Chirurgia delle vene cave
- Author
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Irace, Luigi, Laurito, Antonella, Giannoni, Maria Fabrizia, Castiglione, A, Gattuso, Roberto, Venosi, Salvatore, Martinelli, Ombretta, Gossetti, Bruno, Salvatori, Fm, and BENEDETTI VALENTINI, Fabrizio
- Published
- 2008
5. Complete recanalization of a completely obstructed cervical esophagus with an endoscopic-radiologic rendez-vous and self-expanding stent
- Author
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DE VINCENTIIS, M, Fiocca, Fausto, Salvatori, Fm, Ceci, V, Donatelli, G, Corona, M, Boatta, E, and Gallo, A.
- Published
- 2007
6. COMPLETE RECANALIZATION OF A COMPLETELY OSTRUCTED CERVICAL ESOPHAGUS WITH AN ENDOSCOPIC-RADIOLOGIC RENDEZ-VOUS AND SELF EXPANDING STENT
- Author
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DE VINCENTIIS, Marco, Fiocca, F, Salvatori, Fm, Ceci, V, Donatelli, G, Corona, M, Boatta, E, and Gallo, Andrea
- Published
- 2007
7. Retroperitoneal fibrosis and periaortitis: unusual complication after EVAR
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Giannoni, Maria Fabrizia, Irace, L, Salvatori, Fm, and Gossetti, Bruno
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Abdominal Aortic Aneurysm ,EVAR ,Retroperitoneal fibrosis ,periaortitis ,Contrast Enhanced Ultrasonography - Published
- 2007
8. THE IMPACT OF TIPSS ON LIVER TRANSPLANTATION
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Cortesini, Raffaello, Alfani, D, Rossi, Massimo, DE SIMONE, P, Casciaro, Giovanni Enrico, Iappelli, Massimo, Novelli, Gilnardo, Urbano, D, Trentino, P, Rossi, P, Salvatori, Fm, Antonini, M, and DELLA ROCCA, G.
- Published
- 1997
9. Superior mesenteric artery ischemia: endovascular approach
- Author
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Patrizi, G, primary, Fazi, M, additional, Fiengo, L, additional, Di Rocco, G, additional, Giannotti, D, additional, Pelle, F, additional, Frezzotti, F, additional, Giordano, R, additional, Venturini, L, additional, Redler, A, additional, and Salvatori, FM, additional
- Published
- 2011
- Full Text
- View/download PDF
10. Right colon angiodysplasia and lower limb chronic obstructive arteropathy: simultaneous endovascular treatment
- Author
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Patrizi, G, primary, Fazi, M, additional, Fiengo, L, additional, Di Rocco, G, additional, Pelle, F, additional, Giannotti, D, additional, Venturini, L, additional, Frezzotti, F, additional, Giordano, R, additional, Redler, A, additional, and Salvatori, FM, additional
- Published
- 2011
- Full Text
- View/download PDF
11. Radiologia interventistica nella terapia palliativa e nel trattamento delle lesioni iatrogene
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Rossi, P, Ricci, Paolo, Salvatori, Fm, Bezzi, Mario, Rossi, Michele, and Orsi, F.
- Published
- 1993
12. Percutaneous treatment of symptomatic renal cysts with ethaa\ nol cysts with eahanol and fibrin tissue adhesive
- Author
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Drudi, Francesco Maria, Bezzi, M., and Salvatori, Fm
- Published
- 1991
13. Management strategies for thoracic stent-graft repair of distal aortic arch lesions: is intentional subclavian artery occlusion a safe procedure?
- Author
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Fanelli F, Dake MD, Salvatori FM, Pucci A, Mazzesi G, Lucatelli P, Rossi P, Passariello R, Fanelli, Fabrizio, Dake, Michael D, Salvatori, Filippo Maria, Pucci, Armando, Mazzesi, Giuseppe, Lucatelli, Pierleone, Rossi, Plinio, and Passariello, Roberto
- Abstract
The aim of this retrospective analysis was to assess the clinical consequences after intentional left subclavian artery (LSA) occlusion. Thirty-seven patients, 27 type B dissection and 10 thoracic aneurysm, with short proximal neck (less than 2 cm) underwent endovascular treatment with intentional exclusion of LSA origin. No immediate complications occurred. Mean arterial pressure gradient, between right and left arms, ranged from 15 to 45 mmHg. After a mean follow-up of 43.70 + or - 24.01 months, mild left arm symptoms secondary to flow reduction occurred in eight cases (21.6%) but only one required LSA transposition, after 8 months, for visual impairment. Type II endoleaks from excluded LSA occurred in 10 cases (27.0%): in seven patients, leaks were treated with coils and/or glue embolization; in one case, leak sealed spontaneously; one patient died before leak embolization could occur; one patient refused any further treatment. Intentional exclusion of the LSA may be justified when a longer proximal landing zone in the aortic arch is required. [ABSTRACT FROM AUTHOR]
- Published
- 2009
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14. Low-dose contrast-enhanced time-resolved MR angiography at 3T: Diagnostic accuracy for treatment planning and follow-up of vascular malformations.
- Author
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Anzidei M, Cavallo Marincola B, Napoli A, Saba L, Zaccagna F, Lucatelli P, Fanelli F, Bassetti E, Salvatori FM, Catalano C, and Passariello R
- Abstract
AIM: To assess the accuracy of low-dose contrast-enhanced time-resolved 3T magnetic resonance angiography (MRA) for the morphological and functional assessment of vascular malformations (VM), and to evaluate its diagnostic potential for the depiction of treatment-induced changes. MATERIALS AND METHODS: Twenty-five patients with known VM underwent MRA to evaluate the location and extent of lesions and their haemodynamic characteristics. Three-dimensional (3D) T1-weighted time-resolved sequences were acquired following the administration of 0.05mmol/kg of gadobenate dimeglumine. VM were classified according to their morphology and haemodynamic characteristics. All patients thereafter underwent conventional angiography to confirm the diagnosis and to treat the lesions (embolization or sclerotherapy). Follow-up MRA was performed 30 days after treatment to assess morphological and functional changes. A visual analogue scale (VAS) was used to clinically assess the severity of symptoms before and after therapy. RESULTS: Based on haemodynamic characteristics, VM were classified as predominantly arterial [4 (16%)], artero-venous [19 (76%)] or venous [2 (8%)]. Twenty-three (92%) lesions were classified as high-flow VM and two (8%) as low-flow VM. Intralesional thrombosis was present in 17 (68%) lesions before therapy and in 10 lesions (40%) after therapy. The median VAS scores were 5±1 before treatment and 4±2 after treatment. Very good correlation (Spearman's correlation coefficient: rho=0.87; p=0.000) was noted between the reduction of lesion size on follow-up MRA and pain relief as assessed by VAS. CONCLUSION: Low-dose contrast-enhanced time-resolved 3T MRA can be used to define morphological and functional aspects of VM accurately during treatment planning and follow-up, and can identify post-therapy changes that positively correlate with treatment outcome. [ABSTRACT FROM AUTHOR]
- Published
- 2011
15. Complete transection of the main bile duct: minimally invasive treatment with an endoscopic-radiologic rendezvous
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Antonio Bruni, Gianfranco Donatelli, V. Ceci, Filippo Maria Salvatori, Mario Corona, Fabrizio Fanelli, Fausto Fiocca, Fiocca, F, Salvatori, Fm, Fanelli, F, Bruni, A, Ceci, V, Corona, M, and Donatelli, G
- Subjects
Male ,Reoperation ,medicine.medical_specialty ,Percutaneous ,medicine.medical_treatment ,Population ,Asymptomatic ,Diagnosis, Differential ,Postoperative Complications ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Cholecystectomy ,education ,Retrospective Studies ,Cholangiopancreatography, Endoscopic Retrograde ,Common Bile Duct ,education.field_of_study ,Common bile duct ,business.industry ,Bile duct ,Gastroenterology ,Retrospective cohort study ,Jaundice ,Middle Aged ,Plastic Surgery Procedures ,Surgery ,surgical procedures, operative ,medicine.anatomical_structure ,Treatment Outcome ,Female ,medicine.symptom ,business - Abstract
Background Complete transection of the common bile duct (CBD) is a dramatic and often extremely difficult-to-repair event after surgery. Abdominal biliary fluid collection or jaundice is the initial symptom, and ERCP is the determinant for diagnosis. Objective To evaluate the safety and efficacy of a combined endoscopic-radiologic technique for the reconstruction of the CBD. Design Single-center retrospective study. Setting Tertiary-care center for biliary surgery. Patients This study involved 22 patients with complete transection of the CBD after cholecystectomy. Intervention A guidewire is passed in the subhepatic space through the endoscopic approach. A snare loop is advanced from the percutaneous entry site to catch the free end of the wire and then pulled outside the body: a percutaneous biliary-duodenal (PTBD) drainage is put in place. After a new contralateral PTBD, 4 plastic stents are inserted. The stents are removed endoscopically after 8 to 12 months. Main Outcome Measurements Success of the rendezvous maneuver, patient recovery, and patient mortality. Results After a mean follow-up period of 4 years, 16 patients are asymptomatic. Two patients are still under treatment, and 4 patients underwent surgery, as was the surgeon's choice. Limitations Single-center, retrospective study with a small population. Conclusion Interruption of the biliary tree does not represent an indication for an often-difficult surgical treatment, because the CBD is often thin in the presence of biliary peritonitis. However, the condition can be treated with a rendezvous technique. Surgery can be performed in elective conditions or completely avoided when conservative therapy is selected.
- Published
- 2011
16. Minimally Invasive Treatment of Benign Complete Stenosis of Colorectal Anastomosis
- Author
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V. Ceci, Fabrizio Cereatti, A. Bruni, Fausto Fiocca, Gianfranco Donatelli, S. Minervini, F. M. Salvatori, Donatelli, G, Ceci, V, Cereatti, F, Bruni, A, Salvatori, Fm, Minervini, S, and Fiocca, F.
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Adult ,Male ,medicine.medical_specialty ,Colon ,medicine.medical_treatment ,Rectum ,Constriction, Pathologic ,Anastomosis ,Balloon ,Catheterization ,Ileostomy ,Colon surgery ,medicine ,Humans ,Colectomy ,Aged ,business.industry ,Anastomosis, Surgical ,Gastroenterology ,Stent ,Colonoscopy ,medicine.disease ,Surgery ,Stenosis ,medicine.anatomical_structure ,Female ,Stents ,business ,Transjugular intrahepatic portosystemic shunt - Abstract
rectal surgery are leaks and stenosis, which occur with a frequency of 0.3%± 30% [1,2]. Strictures are commonly treated with conservative treatments such as balloon dilatation, endoscopic incision, and placement of self-expanding metal stent (SEMS) [3±5]. Two patients with complete colorectal anastomotic closure were successfully treated with an endoscopic±radiologic rendezvous procedure. A 27-year-old woman who had undergone low anterior resection due to cancer of the rectum, and a 69-year-old man who had undergone left colonic resection because of acute diverticulitis were referred to our department. Both patients had a loop ileostomy. Endoscopic and radiologic follow-up before recanalization showed complete anastomotic stricture (l" Fig. 1) at 8 cm and 16 cm from the anal verge, respectively. In both patients malignancy was excluded by means of multiple biopsies. Both patients were treated as follows. An incision of the fibrotic stenosis of the anastomosis was made through the rectum using a needle normally used for transjugular intrahepatic portosystemic shunt (TIPS). Direct vision of the puncture place was assured by an anterograde colonoscopy from the ileostomy (l" Fig. 2). A guide wire was passed through and a drainage catheter was placed. The drainage catheter was kept in place for 3 days (l" Fig. 3). Following two balloon dilatations, a fully covered and removable stent was placed (l" Fig. 4). After 60 days, the stent was removed (l" Fig. 5). In one patient the stent gave mild tenesmus, which was alleviated by analgesic drugs. In both patients the neo-anastomosis (l" Fig. 6) was still wide open and functioning well after 24 months. Even in such difficult cases, in which the use of surgery seemed inevitable and furthermore not free of risks, the cooperation between endoscopist and radiologist made conservative treatment possible. The placement of removable SEMS in order to maintain an adequate lumen and to eliminate any possible leak was demonstrated to be a safe and efficient technique.
- Published
- 2008
17. ATOM Classification of Bile Duct Injuries During Laparoscopic Cholecystectomy: Analysis of a Single Institution Experience.
- Author
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Balla A, Quaresima S, Corona M, Lucatelli P, Fiocca F, Rossi M, Bezzi M, Catalano C, Salvatori FM, Fingerhut A, and Paganini AM
- Subjects
- Abdominal Injuries diagnostic imaging, Abdominal Injuries surgery, Adult, Aged, Aged, 80 and over, Cholangiography, Cholangiopancreatography, Endoscopic Retrograde, Female, Humans, Male, Middle Aged, Time Factors, Abdominal Injuries classification, Abdominal Injuries etiology, Blood Vessels injuries, Cholecystectomy, Laparoscopic adverse effects, Common Bile Duct injuries
- Abstract
Purpose: Bile duct injuries (BDIs) are more frequent during laparoscopic cholecystectomy (LC). Several BDI classifications are reported, but none encompasses anatomy of damage and vascular injury (A), timing of detection (To), and mechanism of damage (M). Aim was to apply the ATOM classification to a series of patients referred for BDI management after LC., Methods: From 2008 to 2016, 26 patients (16 males and 10 females, median age 63 years, range 34-82 years) with BDIs were observed. Fifteen patients were managed by percutaneous transhepatic cholangiography (PTC)+endoscopic retrograde cholangiopancreatography (ERCP); five and six underwent PTC and ERCP alone, respectively. Median overall follow-up duration was 34 months. Three patients died from sepsis., Results: Out of 26 patients, 20 presented with main bile duct and six with nonmain bile duct injuries. Using the ATOM classification, every aspect of the BDI in every case was included, unlike with other classifications (Neuhaus, Lau, Strasberg, Bergman, and Hanover)., Conclusions: The all-inclusive European Association for Endoscopic Surgery (EAES) classification contains objective data and emphasizes the underlying mechanisms of damage, which is relevant for prevention. It also integrates vascular injury, necessary for ultimate management, and timing of discovery, which has diagnostic implications. The management complexity of these patients requires specialized referral centers.
- Published
- 2019
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18. Angioseal VIP® vs. StarClose SE® closure devices: a comparative analysis in non-cardiological procedures.
- Author
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Lucatelli P, Fanelli F, Cannavale A, Corona M, Cirelli C, D'Adamo A, Salvatori FM, and Catalano C
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- Adult, Aged, Aged, 80 and over, Equipment Design, Equipment Failure, Female, Hemorrhage etiology, Hemostatic Techniques adverse effects, Humans, Male, Middle Aged, Punctures, Recurrence, Retrospective Studies, Risk Factors, Time Factors, Treatment Outcome, Young Adult, Endovascular Procedures adverse effects, Femoral Artery injuries, Hemorrhage prevention & control, Hemostatic Techniques instrumentation, Vascular Closure Devices
- Abstract
Background: The aim of this paper was to compare the use of two different commercially available vascular closure devices (VCD), Angioseal VIP® (St. Jude Medical, St. Paul, MN, USA) and StarClose SE (Abbott Laboratories, Abbott Park, IL, USA)., Methods: From January 2010 to January 2012, 347 patient underwent retrograde femoral arterial puncture for different interventional procedures (angioplasty, stenting, embolization for bleeding, fibrinolysis for ischemia and chemoembolization). Hemostasis was achieved by deployment of an Angioseal VIP® (N.=184) or StarClose SE® (N.=163). In 94 cases, the retrograde femoral access was bilateral and managed with two StarClose SE devices (N.=53) or an Angioseal VIP® plus a StarClose SE® (N.=41)., Results: Technical success was obtained in 95.1% (330/347) of patients. Overall time to hemostasis (TTH) and time to ambulation (TTA) were 5,5±1,5 min (range 3-8 min) and 6±2.5 hr (range 2-9 hours) respectively. No statistical significative difference (P>0.05) were appreciable between to groups for both TTH and TTA: Angioseal VIP® TTH was 5.3±1.4 min and StarClose SE® TTH was 5.6±1.6 min; Angioseal VIP® TTA was 5.9±1.8 hr and StarClose SE® TTA was 6.1±1.9 hr. VAS scores result underline a mild difference between two devices. Angioseal VIP® patients experience a mild to moderate pain within the first 3 minutes from the deployment. Whereas StarClose SE® patients still experience pain at 5 minutes from deployment. The device failure rate was 4.9% (17 cases) and included 13 minor complications and 4 major complications. Minor complications (3.75%) occurred during the initial phase and consisted in recurrent wound bleeding (N.=5 StarClose SE®; N.=4 Angioseal VIP®) treated with manual compression, and hematoma (N.=2 StarClose SE®; N.=2 Angioseal VIP®) that solved spontaneously. The 4 major complications (1,15%) were: 1 Angioseal-related common femoral artery (CFA) obstruction treated with surgical bypass from the CFA to the superficial femoral artery; 1 Angioseal-related CFA dissection solved with surgery; 1 Angioseal-related embolization of the deep femoral artery partially treated with localized fibrinolysis; 1 StarClose-related pseudoaneurysm treated with manual compression., Conclusions: Both Angioseal VIP® and StarClose SE® systems can be considered safe and effective in providing hemostasis following a variety of interventional vascular procedures.
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- 2017
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19. No effect of albumin infusion on the prevention of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt.
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Riggio O, Nardelli S, Pasquale C, Pentassuglio I, Gioia S, Onori E, Frieri C, Salvatori FM, and Merli M
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- Adult, Aged, Female, Follow-Up Studies, Hepatic Encephalopathy blood, Humans, Infusions, Intravenous, Male, Middle Aged, Pilot Projects, Portasystemic Shunt, Transjugular Intrahepatic trends, Postoperative Complications blood, Postoperative Complications etiology, Postoperative Complications prevention & control, Treatment Outcome, Hepatic Encephalopathy etiology, Hepatic Encephalopathy prevention & control, Portasystemic Shunt, Transjugular Intrahepatic adverse effects, Serum Albumin, Human administration & dosage
- Abstract
Hepatic encephalopathy (HE) is a major problem in patients submitted to TIPS. Previous studies identified low albumin as a factor associated to post-TIPS HE. In cirrhotics with diuretic-induced HE and hypovolemia, albumin infusion reduced plasma ammonia and improved HE. Our aim was to evaluate if the incidence of overt HE (grade II or more according to WH) and the modifications of venous blood ammonia and psychometric tests during the first month after TIPS can be prevented by albumin infusion. Twenty-three patients consecutively submitted to TIPS were enrolled and treated with 1 g/Kg BW of albumin for the first 2 days after TIPS followed by 0,5 g/Kg BW at day 4th and 7th and then once a week for 3 weeks. Forty-five patients included in a previous RCT (Riggio et al. 2010) followed with the same protocol and submitted to no pharmacological treatment for the prevention of HE, were used as historical controls. No differences in the incidence of overt HE were observed between the group of patients treated with albumin and historical controls during the first month (34 vs 31 %) or during the follow-up (39 vs 48 %). Two patients in the albumin group and three in historical controls needed the reduction of the stent diameter for persistent HE. Venous blood ammonia levels and psychometric tests were also similarly modified in the two groups. Survival was also similar. Albumin infusion has not a role in the prevention of post-TIPS HE.
- Published
- 2016
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20. Cognitive Impairment Predicts The Occurrence Of Hepatic Encephalopathy After Transjugular Intrahepatic Portosystemic Shunt.
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Nardelli S, Gioia S, Pasquale C, Pentassuglio I, Farcomeni A, Merli M, Salvatori FM, Nikolli L, Torrisi S, Greco F, Nicoletti V, and Riggio O
- Subjects
- Adult, Aged, Female, Humans, Liver Cirrhosis therapy, Male, Middle Aged, Psychometrics, Risk Factors, Cognitive Dysfunction etiology, Hepatic Encephalopathy etiology, Portasystemic Shunt, Transjugular Intrahepatic adverse effects
- Abstract
Objectives: Hepatic encephalopathy (HE) is a major problem in patients treated with TIPS. The aim of the study was to establish whether pre-TIPS covert HE is an independent risk factor for the development of HE after TIPS., Methods: Eighty-two consecutive cirrhotic patients submitted to TIPS were included. All patients underwent the PHES to identify those affected by covert HE before a TIPS. The incidence of the first episode of HE was estimated, taking into account the nature of the competing risks in the data (death or liver transplantation)., Results: Thirty-five (43%) patients developed overt HE. The difference of post-TIPS HE was highly significant (P=0.0003) among patients with or without covert HE before a TIPS. Seventy-seven percent of patients with post-TIPS HE were classified as affected by covert HE before TIPS. Age: (sHR 1.05, CI 1.02-1.08, P=0.002); Child-Pugh score: (sHR 1.29, CI 1.06-1.56, P=0.01); and covert HE: (sHR 3.16, CI: 1.43-6.99 P=0.004) were associated with post-TIPS HE. Taking into consideration only the results of PHES evaluation, the negative predicting value was 0.80 for all patients and 0.88 for the patients submitted to TIPS because of refractory ascites. Thus, a patient with refractory ascites, without covert HE before a TIPS, has almost 90% probability of being free of HE after TIPS., Conclusions: Psychometric evaluation before TIPS is able to identify most of the patients who will develop HE after a TIPS and can be used to select patients in order to have the lowest incidence of this important complication.
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- 2016
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21. Non-vascular interventional procedures: effective dose to patient and equivalent dose to abdominal organs by means of DICOM images and Monte Carlo simulation.
- Author
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Longo M, Marchioni C, Insero T, Donnarumma R, D'Adamo A, Lucatelli P, Fanelli F, Salvatori FM, Cannavale A, and Di Castro E
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- Aged, Anthropometry, Female, Humans, Male, Middle Aged, Radiation Dosage, Radiometry methods, X-Rays, Abdomen diagnostic imaging, Monte Carlo Method, Phantoms, Imaging, Radiology, Interventional methods
- Abstract
This study evaluates X-ray exposure in patient undergoing abdominal extra-vascular interventional procedures by means of Digital Imaging and COmmunications in Medicine (DICOM) image headers and Monte Carlo simulation. The main aim was to assess the effective and equivalent doses, under the hypothesis of their correlation with the dose area product (DAP) measured during each examination. This allows to collect dosimetric information about each patient and to evaluate associated risks without resorting to in vivo dosimetry. The dose calculation was performed in 79 procedures through the Monte Carlo simulator PCXMC (A PC-based Monte Carlo program for calculating patient doses in medical X-ray examinations), by using the real geometrical and dosimetric irradiation conditions, automatically extracted from DICOM headers. The DAP measurements were also validated by using thermoluminescent dosemeters on an anthropomorphic phantom. The expected linear correlation between effective doses and DAP was confirmed with an R(2) of 0.974. Moreover, in order to easily calculate patient doses, conversion coefficients that relate equivalent doses to measurable quantities, such as DAP, were obtained., (© The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)
- Published
- 2016
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22. Combined radiological-endoscopic management of difficult bile duct stones: 18-year single center experience.
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Cannavale A, Bezzi M, Cereatti F, Lucatelli P, Fanello G, Salvatori FM, Fanelli F, Fiocca F, and Donatelli G
- Abstract
Objectives: Clinical evidence regarding radiological-endoscopic management of intrahepatic bile duct stones is currently lacking. Our aim is to report our 18-year experience in combined radiological-endoscopic management of intrahepatic difficult bile duct stones., Methods: From June 1994 to June 2012, 299 symptomatic patients with difficult bile duct stones were admitted to our institution. Percutaneous transhepatic cholangiography (PTC)/biliary drainage/s was performed, dilating the PTC track to 10 or 16 French within 3-7 days. Afterward we carried out percutaneous transhepatic cholangioscopy (PTCS) with electrohydraulic lithotripsy (EHL) and/or interventional radiology techniques. Follow up was made with clinical/laboratory tests and ultrasound (US). We retrospectively analyzed our radiological-endoscopic approach and reported our technical and clinical outcomes., Results: Complete stone clearance was achieved in 298 patients after a maximum of 4 consecutive sessions. Most patients (64.6%) were treated with PTCS/EHL alone, while the remaining with radiological techniques alone (26%) or a combination of both techniques (13.3%). Recurrence of stones occurred in 45 cases (15%, Tsunoda class III and class IV) within 2 years and were successfully retreated. Major adverse events were: 5 (1.6%) cases of massive bleeding that required embolisation, 2 (0.66%) perforations of the common bile duct and 31 cases (10.3%) of acute cholangitis managed with medical therapy or intervention., Conclusion: After 18 years of experience we demonstrated that our combined radiological-endoscopic approach to 'difficult bile duct stones' may result in both immediate and long-term clearance of stones with a low rate of adverse events.
- Published
- 2015
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23. Aortic pseudoaneurysm rupture secondary to pancreatitis: An endovascular approach.
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Corona M, Boatta E, Lucatelli P, Ricœur A, Salvatori FM, and Zini C
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- Female, Humans, Middle Aged, Aneurysm, False etiology, Aneurysm, False surgery, Aortic Aneurysm, Abdominal etiology, Aortic Aneurysm, Abdominal surgery, Aortic Rupture etiology, Aortic Rupture surgery, Endovascular Procedures, Pancreatitis complications
- Published
- 2015
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24. Use of ultrasound in the insertion of a vascular closure device: a comparative retrospective study with the standard blind technique.
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Lucatelli P, Cannavale A, Cirelli C, d'Adamo A, Salvatori FM, and Fanelli F
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- Adult, Aged, Aneurysm, False etiology, Female, Follow-Up Studies, Hematoma etiology, Hemorrhage etiology, Humans, Male, Middle Aged, Punctures, Reproducibility of Results, Retrospective Studies, Risk Factors, Time Factors, Femoral Artery surgery, Hemorrhage prevention & control, Hemostasis, Ultrasonography, Interventional adverse effects, Vascular Closure Devices adverse effects
- Abstract
Purpose: To evaluate whether ultrasound (US) assistance can decrease the rate of complications related to the use of vascular closure devices (VCDs)., Materials and Methods: A retrospective comparative study was done on 150 consecutive patients who had a VCD inserted under US guidance after retrograde common-femoral-artery (CFA) puncture. This group was compared to a historical control group of 150 consecutive patients who had the same VCDs inserted with the standard blind technique. After the procedures, patients were placed at bedrest for at least 6 h. Technical success, defined as correct deployment without adjunctive manual compression, blood count and US evaluation of the arterial puncture site was done at 24 h and at 3 months. Differences in terms of efficacy and safety were statistically evaluated using US guidance as a predictor for a lower complication rate., Results: Technical success was achieved in 147/150 patients (98 %) in the study group vs. 141/150 cases (94 %) of the control group (p = 0.038). In three cases (2 %) adjunctive manual compression (≤5 min) was required. One pseudoaneurysm (0.65 %) occurred after 24 h, solved with manual compression. Six minor complications (4 %)--haematoma (n = 5; 3.35 %), recurrent wound bleeding (n = 1; 0.65 %)--were reported. In the control group four (2.65 %) major complications occurred: CFA occlusion managed with surgical bypass, CFA dissection solved by surgical bypass, two pseudoaneurysms solved with manual compression. Thirteen (8.65 %) minor complications were observed with haematoma (n = 10; 6.65 %), and recurrent wound bleeding (n = 3; 2.0 %). The comparative analysis of the total complication rate and major complication rate between the study group and the control group was statistically significant (p = 0.016 and p = 0.049, respectively). A 24-h evaluation showed a triphasic flow within the CFA in 150/150 patients (100 %) of the study group and in 146/150 cases (97.35 %) of the control group., Conclusion: VCD inserted under US guidance increases the success rate reducing the number of complications.
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- 2015
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25. Transplantation of human fetal biliary tree stem/progenitor cells into two patients with advanced liver cirrhosis.
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Cardinale V, Carpino G, Gentile R, Napoletano C, Rahimi H, Franchitto A, Semeraro R, Nuti M, Onori P, Berloco PB, Rossi M, Bosco D, Brunelli R, Fraveto A, Napoli C, Torrice A, Gatto M, Venere R, Bastianelli C, Aliberti C, Salvatori FM, Bresadola L, Bezzi M, Attili AF, Reid L, Gaudio E, and Alvaro D
- Subjects
- Aged, Antigens, Neoplasm metabolism, Biliary Tract cytology, Cell Adhesion Molecules metabolism, Epithelial Cell Adhesion Molecule, Female, Hepatic Artery, Humans, Male, Fetal Tissue Transplantation methods, Liver Cirrhosis therapy, Stem Cell Transplantation methods
- Abstract
Background: Efforts to identify cell sources and approaches for cell therapy of liver diseases are ongoing, taking into consideration the limits recognized for adult liver tissue and for other forms of stem cells. In the present study, we described the first procedure of via hepatic artery transplantation of human fetal biliary tree stem cells in patients with advanced cirrhosis., Methods: The cells were immune-sorted from human fetal biliary tree by protocols in accordance with current good manufacturing practice (cGMP) and extensively characterized. Two patients with advanced liver cirrhosis (Child-Pugh C) have been submitted to the procedure and observed through a 12 months follow-up., Results: The resulting procedure was found absolutely safe. Immuno-suppressants were not required, and the patients did not display any adverse effects correlated with cell transplantation or suggestive of immunological complications. From a clinical point of view, both patients showed biochemical and clinical improvement during the 6 month follow-up and the second patient maintained a stable improvement for 12 months., Conclusion: This report represents proof of the concept that the human fetal biliary tree stem cells are a suitable and large source for cell therapy of liver cirrhosis. The isolation procedure can be carried out under cGMP conditions and, finally, the infusion procedure is easy and safe for the patients. This represents the basis for forthcoming controlled clinical trials.
- Published
- 2014
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26. Percutaneous vertebroplasty with the rotational fluoroscopy imaging technique.
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Cannavale A, Salvatori FM, Wlderk A, Cirelli C, d'Adamo A, and Fanelli F
- Subjects
- Equipment Design, Equipment Failure Analysis, Female, Fluoroscopy instrumentation, Humans, Male, Middle Aged, Multimodal Imaging instrumentation, Multimodal Imaging methods, Radiography, Interventional instrumentation, Retrospective Studies, Rotation, Tomography, X-Ray Computed instrumentation, Treatment Outcome, X-Ray Intensifying Screens, Bone Cements therapeutic use, Fluoroscopy methods, Radiography, Interventional methods, Spinal Fractures diagnostic imaging, Spinal Fractures therapy, Tomography, X-Ray Computed methods, Vertebroplasty methods
- Abstract
Objective: To evaluate the feasibility of the rotational angiography unit (RAU) as a single technique to guide percutaneous vertebroplasty (PVP)., Materials and Methods: Twenty-five consecutive patients (35 vertebral bodies, 20 lumbar and 15 thoracic) were treated using RA fluoroscopy. Using a state-of-the-art flat-panel angiographer (Artis zee, Siemens, Erlangen, Germany), rotational acquisitions were obtained in all patients for immediate post-procedure 2D/3D reconstructions. Pre- and postoperative back pain was assessed with the visual analog scale (VAS). Fluoroscopy time, patient radiation dose exposure, technical success, mean procedure time, mean number of rotational acquisitions and procedural complications were recorded. All features were compared with a historical cohort of patients (N = 25) who underwent PVP under CT and mobile C-arm fluoroscopy guidance., Results: In all cases, safe and accurate control of the needle insertion and bone-cement injection was successfully obtained with high-quality fluoroscopy images. One cement leakage was detected in the RAU group, and two leakages were detected in the CT and C-arm fluoroscopy group. Technical features were significantly different between the two groups (RAU vs. CT): mean procedure time: 38.2 min vs. 60.2 min (p = 0.02); median fluoroscopy time: 14.58 and 4.58 min (p = 0.02); median number of rotational acquisitions: 5 vs. 10 (p = 0.02); mean patient dose: 6 ± 1.3 mSv vs. 23 ± 1.3 mSv (p = 0.02). There were minor complications (pain, small hematoma) in two patients (8%) in the study group and three cases (12%) in the control group., Conclusion: RAU guidance is an effective and safe technique for performing PVP because it reduces the procedural time and radiation exposure.
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- 2014
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27. Calcium burden assessment and impact on drug-eluting balloons in peripheral arterial disease.
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Fanelli F, Cannavale A, Gazzetti M, Lucatelli P, Wlderk A, Cirelli C, d'Adamo A, and Salvatori FM
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- Aged, Angiography, Arterial Occlusive Diseases diagnostic imaging, Female, Humans, Limb Salvage, Lower Extremity blood supply, Lower Extremity diagnostic imaging, Male, Middle Aged, Peripheral Vascular Diseases diagnostic imaging, Stents, Treatment Outcome, Ultrasonography, Angioplasty, Balloon instrumentation, Arterial Occlusive Diseases blood, Arterial Occlusive Diseases therapy, Calcium blood, Drug Carriers, Endovascular Procedures, Femoral Artery, Peripheral Vascular Diseases blood, Peripheral Vascular Diseases therapy
- Abstract
Purpose: This study was designed to assess the effect of calcium on the efficacy of DEB during revascularization of steno-obstructive SFA lesions., Methods: Sixty patients with de novo lesions of the superficial femoral artery underwent endovascular treatment with drug eluting balloons (DEB). DEB was selected according to vessel reference diameter (1:1). In case of residual stenosis > 50 % or flow-limiting dissection, postdilatation with conventional balloon or provisional stenting was done. Patients were classified into eight groups according to circumferential distribution of calcium on CT-angiography axial images (from 0° to 360°) and to its length (length < or > 3 cm) evaluated with digital-subtraction-angiography. Ankle-brachial index (ABI), late lumen loss (LLL), target lesion revascularization (TLR), primary (PP) and secondary (SP) patency, major adverse events (MAE), and Rutherford shift were evaluated at 1-year follow-up and correlated with the amount of calcium., Results: Revascularization was successful in all cases. Flow-limiting dissection occurred in five cases (8.3 %) with a higher circumferential degree of calcium and solved in three cases with postdilatation and in the other two with provisional stenting. DEB effect was lower in patients with higher degree of calcium (>270° vs. <90°): ABI 0.71 ± 0.07 versus 0.92 ± 0.07; LLL 0.75 ± 0.21 versus 0.45 ± 0.1; PP 50 versus 100 %; SP 50 versus 100 %; TLR 25 versus 0 %; MAE 25 versus 0 %., Conclusions: Calcium represents a barrier to optimal drug absorption. Circumferential distribution seems to be the most influencing factor with the worst effect noticed in 360° calcium presence.
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- 2014
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28. Hepatocellular carcinoma in cirrhotic patients with transjugular intrahepatic portosystemic shunt: a retrospective case-control study.
- Author
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De Santis A, Iegri C, Kondili L, Riggio O, Salvatori FM, Catalano C, Di Martino M, Bassanelli C, Lupo M, Lucatelli P, and Attili AF
- Subjects
- Aged, Carcinoma, Hepatocellular diagnostic imaging, Case-Control Studies, Female, Follow-Up Studies, Humans, Hypertension, Portal etiology, Hypertension, Portal therapy, Incidence, Liver Neoplasms diagnostic imaging, Male, Middle Aged, Retrospective Studies, Severity of Illness Index, Survival Rate, Ultrasonography, Carcinoma, Hepatocellular epidemiology, Liver Cirrhosis complications, Liver Neoplasms epidemiology, Population Surveillance, Portasystemic Shunt, Transjugular Intrahepatic mortality
- Abstract
Background: An association between Transjugular Intrahepatic Porto-Systemic Shunt (TIPS) and the development of hepatocellular carcinoma in patients with cirrhosis has been suggested, but not confirmed., Aim: To evaluate the potential role of TIPS in hepatocellular carcinoma development., Methods: We performed a retrospective case-control study among patients with cirrhosis; all cases had undergone TIPS placement. Cases and controls were followed as outpatients at a single liver care centre in the same timeframe., Results: Overall, 101 patients with cirrhosis (mean age 58 ± 9 years, 64.3% male) were included in each group. Median duration of follow-up was 56.7 months (range 8.2-174.5) for TIPS patients and 67.8 months (range 8.3-183.1) for controls (p=0.08). In both groups 94% of patients had Child-Pugh Class A or B cirrhosis. The cumulative incidence of hepatocellular carcinoma at 1, 3, 5, and 10 years was 2%, 7%, 18%, and 46% among TIPS patients, and 3%, 10%, 19%, and 39% among controls (log rank test p=0.19). Compared to controls, hepatocellular carcinoma nodules in TIPS patients were more frequently situated in the right lobe (p<0.05)., Conclusions: TIPS does not seem to increase the risk of hepatocellular carcinoma in patients with Child-Pugh Class A or B cirrhosis; for these patients ultrasound surveillance should not be modified., (Copyright © 2014 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.)
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- 2014
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29. The "DEBELLUM"--lower limb multilevel treatment with drug eluting balloon--randomized trial: 1-year results.
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Fanelli F, Cannavale A, Corona M, Lucatelli P, Wlderk A, and Salvatori FM
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- Aged, Aged, 80 and over, Amputation, Surgical, Angioplasty, Balloon adverse effects, Ankle Brachial Index, Critical Illness, Equipment Design, Female, Hemodynamics, Humans, Intermittent Claudication diagnosis, Intermittent Claudication physiopathology, Ischemia diagnosis, Kaplan-Meier Estimate, Limb Salvage, Male, Middle Aged, Peripheral Arterial Disease diagnosis, Peripheral Arterial Disease physiopathology, Risk Factors, Rome, Thrombosis etiology, Time Factors, Treatment Outcome, Vascular Patency, Angioplasty, Balloon instrumentation, Cardiovascular Agents administration & dosage, Drug Carriers, Femoral Artery physiopathology, Intermittent Claudication therapy, Ischemia therapy, Lower Extremity blood supply, Peripheral Arterial Disease therapy, Popliteal Artery physiopathology, Vascular Access Devices
- Abstract
Aim: The aim of the present paper was to make a report of the 12-month clinical outcomes of the DEBELLUM (Drug-Eluting-Balloon-Evaluation-for-Lower-Limb- mUltilevel-treatMent) randomized trial., Methods: From September 2010 to March 2011, 50 patients were randomized between drug eluting balloon (DEB, N.=25) and conventional angioplasty balloon (PTA, N.=25). Patients were symptomatic for claudication and critical limb ischemia, with de novo stenosis or occlusion in the femoropopliteal (SFA) and infrapopliteal (BTK) region. Only in the SFA primary stenting was allowed and postdilatation performed with DEB or PTA depending on the assigned group., Results: One hundred and twenty-two lesions were treated: 92 (75.4%) SFA, 30 (24.6%) BTK. Twenty (40%) patients presented multilevel concomitant femoropopliteal and infra-popliteal lesions. Late lumen loss (LLL) was 0.64±0.9 mm in DEB group vs. 1.81±0.1 mm in the control group (P=0.01). In non-stented segment LLL was 0.63±0.9 mm (DEB) vs. 1.70±0.6 mm (PTA), P<0.01. In the stent subgroup was LLL 0.65±0.2 mm (DEB) vs. 1.91±0.3 mm (PTA), P<0.01. In the femoropopliteal region the overall LLL was 0.61±0.8 mm for DEB vs. 1.84±0.3 mm for PTA (P=0.02). BTK the overall LLL was 0.66±0.9 mm (DEB) vs. 1.69±0.5 mm (PTA) (P=0.03). The overall TLR was 12.2% for DEB and 35.3% for PTA (P<0.05). Amputation rate was 4% (DEB) vs. 12% (PTA), P=0.36. Thrombosis was 4% (DEB) vs. 8% (PTA), P≥0.05. Major adverse events 24% (DEB) vs. 60% (PTA), P<0.05. ABI improved more in the DEB group: 0.81±0.3 vs. 0.68±0.13 (P=0.02). Fontaine stage increased (from II b to I) 80% DEB vs. 56% PTA (P<0.05)., Conclusion: Results confirm and reinforce initial 6-month outcomes. In.Pact DEB balloons can be considered efficient to reduce restenosis rate.
- Published
- 2014
30. Re-TEVAR for complications after blunt aortic traumatic injury stenting.
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Marino M, Kasemi H, Martinelli O, Bresadola L, Salvatori FM, and Irace L
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- Adult, Endovascular Procedures methods, Follow-Up Studies, Graft Occlusion, Vascular diagnostic imaging, Humans, Male, Risk Assessment, Sampling Studies, Stents adverse effects, Thoracic Injuries diagnostic imaging, Thoracic Injuries surgery, Tomography, X-Ray Computed methods, Treatment Outcome, Wounds, Nonpenetrating diagnostic imaging, Blood Vessel Prosthesis, Blood Vessel Prosthesis Implantation methods, Graft Occlusion, Vascular surgery, Prosthesis Failure, Wounds, Nonpenetrating surgery
- Abstract
We report an endovascular approach that was used to treat two patients with previous thoracic aortic repair or endovascular repair (TEVAR) for blunt thoracic aortic injury. The first patient was a 38-year-old man who presented with distal intragraft thrombosis 24 months after TEVAR. The second patient, a 32-year-old man, developed a symptomatic distal device collapse at 39th month follow-up, associated with buttock claudication. Both patients were offered an endograft relining, complicated in the first case by distal embolization.
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- 2014
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31. Selective splenic artery embolization for the treatment of thrombocytopenia and hypersplenism in paroxysmal nocturnal hemoglobinuria.
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Araten DJ, Iori AP, Brown K, Torelli GF, Barberi W, Natalino F, De Propris MS, Girmenia C, Salvatori FM, Zelig O, Foà R, and Luzzatto L
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- Adolescent, Adult, Female, Humans, Male, Young Adult, Embolization, Therapeutic methods, Hemoglobinuria, Paroxysmal therapy, Hypersplenism therapy, Splenic Artery, Thrombocytopenia therapy
- Abstract
Background: PNH is associated with abdominal vein thrombosis, which can cause splenomegaly and hypersplenism. The combination of thrombosis, splenomegaly, and thrombocytopenia (TST) is challenging because anticoagulants are indicated but thrombocytopenia may increase the bleeding risk. Splenectomy could alleviate thrombocytopenia and reduce portal pressure, but it can cause post-operative thromboses and opportunistic infections. We therefore sought to determine whether selective splenic artery embolization (SSAE) is a safe and effective alternative to splenectomy for TST in patients with PNH., Methods: Four patients with PNH and TST received successive rounds of SSAE. By targeting distal vessels for occlusion, we aimed to infarct approximately 1/3 of the spleen with each procedure., Results: Three of 4 patients had an improvement in their platelet count, and 3 of 3 had major improvement in abdominal pain/discomfort. The one patient whose platelet count did not respond had developed marrow failure, and she did well with an allo-SCT. Post-procedure pain and fever were common and manageable; only one patient developed a loculated pleural effusion requiring drainage. One patient, who had had only a partial response to eculizumab, responded to SSAE not only with an improved platelet count, but also with an increase in hemoglobin level and decreased transfusion requirement., Conclusions: These data indicate that SSAE can decrease spleen size and reverse hypersplenism, without exposing the patient to the complications of splenectomy. In addition, SSAE probably reduces the uptake of opsonised red cells in patients who have had a limited response to eculizumab, resulting in an improved quality of life for selected patients.
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- 2014
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32. Transjugular intrahepatic portosystemic shunt for a wait list patient is not a contraindication for orthotopic liver transplant outcomes.
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Levi Sandri GB, Lai Q, Lucatelli P, Melandro F, Guglielmo N, Mennini G, Berloco PB, Fanelli F, Salvatori FM, and Rossi M
- Subjects
- Contraindications, Graft Survival, Humans, Kaplan-Meier Estimate, Patient Selection, Postoperative Complications etiology, Retrospective Studies, Risk Factors, Time Factors, Treatment Outcome, Liver Transplantation mortality, Portasystemic Shunt, Transjugular Intrahepatic mortality, Waiting Lists mortality
- Abstract
Objectives: A transjugular intrahepatic portosystemic shunt for treating recurrent variceal bleeding or refractory ascites can be used as bridge therapy in patients awaiting a liver transplant. However, incorrect placement of the transjugular intrahepatic portosystemic shunt may complicate surgery during a liver transplant. This study sought to analyze a cohort of transplanted recipients to underscore whether transjugular intrahepatic portosystemic shunts can negatively affect liver transplant outcomes., Materials and Methods: We retrospectively analyzed 207 patients who had undergone a liver transplant between January 2001 and December 2009 in the Rome "La Sapienza" center. Transjugular intrahepatic portosystemic shunt was performed before the liver transplant in 36 cases (17%). The analyzed population was stratified into 2 groups (no transjugular intrahepatic portosystemic shunt [n=171 ] and transjugular intrahepatic portosystemic shunt [n=36 ]), and patient survival outcomes were compared., Results: In the no-transjugular intrahepatic portosystemic shunt group, 60 of 171 deaths (35%) were reported, 20 of which were seen in the first 3 months after the liver transplant. In the same group, 61 graft losses (36%) were observed, with 19 of which were seen in the first 3 months after the liver transplant. In transjugular intrahepatic portosystemic shunt group, 12 of the 36 deaths (33%) were seen; 5 patients died within 3 months of the liver transplant. In this latter group, 12 grafts (33%) were lost, 4 of which were reported during the first 3 months after surgery. The median patient survival was 64 months and 69 months in the 2 groups. On survival analysis, no significant differences were found between the 2 groups., Conclusions: Transjugular intrahepatic portosystemic shunt does not seem to affect outcomes after a liver transplant. We suggest that clinicians recognized the location of the stent to prevent any difficulty during surgery.
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- 2013
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33. Minimally invasive treatment of gastric leak after sleeve gastrectomy.
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Corona M, Zini C, Allegritti M, Boatta E, Lucatelli P, Cannavale A, Wlderk A, Cirelli C, Fiocca F, Salvatori FM, and Fanelli F
- Subjects
- Adult, Contrast Media, Diatrizoate Meglumine, Drainage, Female, Humans, Male, Radiography, Interventional, Retrospective Studies, Treatment Outcome, Anastomotic Leak diagnostic imaging, Anastomotic Leak surgery, Gastrectomy methods, Minimally Invasive Surgical Procedures, Obesity, Morbid surgery, Tomography, X-Ray Computed
- Abstract
Purpose: Obesity is a leading problem in Western countries, and laparoscopic sleeve gastrectomy (SG) is the most commonly used procedure for the surgical management of morbid obesity. SG is recognised as one of the safest and most effective bariatric procedures but it is limited by a rate of gastric leaks (GL) ranging from 1.4% to 20%. No international consensus exists about the treatment of GL. This paper reports our experience with the noninvasive management of GL., Materials and Methods: From July 2004 to December 2010, 16 patients with GL after SG were referred to our unit. All patients underwent contrast radiography (Gastrografin) and computed tomography (CT) examination. On the basis of the radiographic findings, patients were divided into those eligible for drainage and those not eligible., Results: Twelve patients (75%) were eligible for percutaneous drainage. Of these, seven patients (44%) were successfully treated with percutaneous drainage alone, whereas five patients (31%) required placement of a covered stent due to incomplete resolution of the collection. After 1009.8±456.7 days of follow-up, one patient died from a cardiovascular event and two patients required a bilio-pancreatic-digestive bypass (BPD-BP). Twelve patients (75%) were in an excellent state of health with significant reduction of their body mass index (BMI)., Conclusions: Our experience confirms the value of an algorithm based on patient eligibility for percutaneous drainage in the treatment of GL. The patient's general condition and in particular the presence of sepsis supports the value of this approach in preference to the conventional surgical approach.
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- 2013
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34. Endovascular treatment of false-aneurysm ten years after dacron patch aortoplasty for coarctation of the aortic isthmus. Report of a case.
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Illuminati G, Pacilè MA, Palumbo P, Salvatori FM, and Vietri F
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- Adult, Female, Humans, Time Factors, Aneurysm, False surgery, Aorta, Thoracic surgery, Aortic Coarctation surgery, Endovascular Procedures, Polyethylene Terephthalates
- Abstract
False aneurysm degeneration is a known complication of patch aortoplasty for coarctation of the aortic isthmus. Open surgical treatment consists of prosthetic graft repair of the involved aorta, often requires circulatory arrest to achieve a safe proximal aortic control and perform proximal anastomosis, and finally is associated with substantial perioperative morbidity. Endografting of the diseased aorta is a valuable alternative to open repair, when feasible, with good short and long term results. We now report one more case of false aneurysm ten years after Dacron patch aortoplasty for isthmic coarctation in a 26-year-old woman, successfully treated by endovascular repair via the left common iliac artery, and a complete exclusion of the aneurysm at two year follow-up.
- Published
- 2013
35. Celiac injury due to arcuate ligament: an endovascular approach.
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Zini C, Corona M, Boatta E, Wlderk A, Salvatori FM, and Fanelli F
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- Accidents, Traffic, Adult, Angiography, Digital Subtraction, Blood Vessel Prosthesis, Catheterization methods, Celiac Artery diagnostic imaging, Contrast Media, Extravasation of Diagnostic and Therapeutic Materials, Hemorrhage diagnostic imaging, Hepatic Artery, Humans, Ligaments diagnostic imaging, Male, Stents, Tomography, X-Ray Computed, Whole Body Imaging, Celiac Artery injuries, Endovascular Procedures, Hemorrhage etiology, Hemorrhage therapy, Ligaments injuries
- Abstract
Celiac trunk injures are rare events, with high mortality rates and difficult management. Endovascular treatment may be considered to avoid bleeding. We report a case of severe bleeding in a 37-year-old man resulting from celiac trunk stretching after a motorcycle crash. Because direct celiac trunk catheterization was not possible, a retrograde catheterization of the common hepatic artery was performed via the superior mesenteric artery. Two vascular plugs (type IV) were released, and the exclusion of the celiac trunk origin was completed with the deployment of an aortic cuff. The patient's clinical condition immediately improved, and after 6 months' follow-up, imaging confirmed the complete exclusion of the celiac trunk.
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- 2013
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36. Carotid artery stenting: analysis of a 12-year single-center experience.
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Fanelli F, Boatta E, Cannavale A, Corona M, Lucatelli P, Wlderk A, Cirelli C, and Salvatori FM
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- Aged, Aged, 80 and over, Angioplasty, Balloon adverse effects, Carotid Artery Diseases complications, Carotid Artery Diseases diagnosis, Carotid Artery Diseases physiopathology, Embolic Protection Devices, Female, Humans, Ischemic Attack, Transient etiology, Magnetic Resonance Angiography, Male, Middle Aged, Prosthesis Design, Recurrence, Retrospective Studies, Risk Factors, Rome, Stroke etiology, Time Factors, Tomography, X-Ray Computed, Treatment Outcome, Ultrasonography, Doppler, Duplex, Vascular Patency, Angioplasty, Balloon instrumentation, Carotid Artery Diseases therapy, Stents
- Abstract
Purpose: To analyze a 12-year experience performing carotid artery stenting (CAS) with cerebral protection., Methods: In accord with NASCET criteria, 672 patients underwent CAS at our hospital between November 1999 and September 2011 for de novo or postsurgical restenosis; among these, 636 patients (474 men; mean age 68 ± 6.8 years, range 63-85) had a minimum 6-month follow-up, which qualified them for this analysis. The majority of patients (381, 59.9%) were symptomatic; 47 patients had staged bilateral CAS procedures (total of 683 procedures). A cerebral protection device was used in 94.7%. Patients underwent duplex ultrasound and clinical evaluation during follow-up. Neurological adverse events were correlated with plaque morphology, patient age >80 years, learning curve, and spasm., Results: Technical success was achieved in all cases. Neurological events [3 (0.4%) major strokes, 8 (1.2%) minor strokes, and 11 (1.6%) transient ischemia attacks] occurred in 22 (3.2%) of the 683 cases within 30 days of the procedure (no events in follow-up). These involved 5 (2.0%) of the 255 asymptomatic patients and 17 (4.5%) of the 381 symptomatic patients (p=0.001). Neurological events proved to be higher in patients >80 years (6.4% vs. 2.7% of patients <80 years, p<0.05) and in those with complex plaque morphology (6.1% vs. 1.0% in stable plaques, p<0.001). After a mean follow-up of 76 ± 32.4 months, 478 (70%) patients were alive, with a 30-day mortality of 1.9% (none due to stroke). In-stent stenosis occurred in 9 (1.3%) stents and was resolved with angioplasty or re-stenting. The primary patency rate was 98.7%., Conclusion: CAS is a valid technique for the treatment of carotid occlusive disease, with a very low rate of in-stent stenosis. Neurological complications were correlated with complex plaque morphology, which makes accurate pretreatment evaluation of the lesion mandatory if good CAS outcomes are to be achieved.
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- 2012
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37. Lower limb multilevel treatment with drug-eluting balloons: 6-month results from the DEBELLUM randomized trial.
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Fanelli F, Cannavale A, Boatta E, Corona M, Lucatelli P, Wlderk A, Cirelli C, and Salvatori FM
- Subjects
- Aged, Aged, 80 and over, Amputation, Surgical, Angioplasty, Balloon adverse effects, Arterial Occlusive Diseases diagnostic imaging, Constriction, Pathologic, Equipment Design, Female, Humans, Limb Salvage, Male, Middle Aged, Prospective Studies, Radiography, Recurrence, Rome, Severity of Illness Index, Stents, Thrombosis etiology, Thrombosis therapy, Time Factors, Treatment Outcome, Angioplasty, Balloon instrumentation, Arterial Occlusive Diseases therapy, Cardiovascular Agents administration & dosage, Drug Carriers, Femoral Artery diagnostic imaging, Lower Extremity blood supply, Paclitaxel administration & dosage, Popliteal Artery diagnostic imaging, Vascular Access Devices
- Abstract
Purpose: To report 6-month results of the DEBELLUM (Drug-Eluting Balloon Evaluation for Lower Limb MUltilevel TreatMent) randomized trial to evaluate the efficacy of a drug-eluting balloon (DEB) to reduce restenosis after treatment of multilevel lower limb occlusive disease vs. a conventional angioplasty balloon (AB)., Methods: Between September 2010 and March 2011, 50 consecutive patients (37 men; mean age 66±4 years) with 122 lesions (96 stenoses and 26 occlusions) of the femoropopliteal (92, 75.4%) or below-the-knee (BTK) arteries (30, 24.6%) were enrolled and randomly assigned to the DEB (25 patients with 57 lesions) or AB (25 patients with 65 lesions) group. Twenty patients presented multilevel lesions. Mean lesion length was 7.5±3.5 cm. Thirty-one (62%) of the patients were Fontaine stage IIb, while 19 (38%) were stage III or IV. DEBs or ABs were used for dilation of de novo lesions or for postdilation after primary stenting (superficial femoral artery only). Patients requiring provisional stenting after angioplasty secondary to flow-limiting dissection or residual stenosis >50% were ineligible. Primary endpoint was late lumen loss at 6 months. Secondary endpoints were target lesion revascularization (TLR), amputation, and thrombosis., Results: Late lumen loss was lower in the DEB group (0.5±1.4 vs. 1.6±1.7 mm, p<0.01). TLR was necessary in 6.1% of the DEB group vs. 23.6% of the AB group (p=0.02). Comparing the DEB to AB groups, the thrombosis rates were 3.0% vs. 5.2% (p=0.6), and the amputation rates were 3.0% vs. 7.9% (p=0.36). The binary restenosis rates were 9.1% (3/33 limbs) in the DEB group vs. 28.9% (11/38 limbs) in the control group (p=0.03). The ankle-brachial index improved to a greater degree in the DEB group: 0.87±0.22 vs. 0.70±0.13 (p<0.05). The Fontaine stage improved in both groups but more so in patients treated with DEBs (p=0.04)., Conclusion: The DEBELLUM trial confirmed the ability of paclitaxel-eluting balloons to reduce restenosis vs. conventional balloons at 6 months after treatment of multilevel (femoropopliteal and BTK) arterial disease in patients affected by claudication and CLI. A lower TLR rate and better clinical outcomes appear to be associated with the use of DEBs regardless of stent placement.
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- 2012
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38. Case report: Percutaneous treatment of multiple honeycomb-like liver hydatid cysts (type III CE2, according to WHO classification).
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Corona M, Cannavale A, Bruni A, Boatta E, Allegritti M, Lucatelli P, Fanelli F, Pucci A, Paciotti C, and Salvatori FM
- Abstract
Percutaneous treatment has been developing as a reliable and effective alternative to surgery in the treatment of liver hydatid cysts. However, percutaneous treatment is strongly recommended only for some types of hydatid cysts (types I and II). We report a patient with type III (CE2, according to the WHO classification) multiple liver hydatid cysts treated with the PAIR (puncture-aspiration-injection-reaspiration) technique. The patient developed a secondary biliary fistula, which ultimately healed.
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- 2012
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39. Complete transection of the main bile duct: minimally invasive treatment with an endoscopic-radiologic rendezvous.
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Fiocca F, Salvatori FM, Fanelli F, Bruni A, Ceci V, Corona M, and Donatelli G
- Subjects
- Common Bile Duct diagnostic imaging, Common Bile Duct surgery, Diagnosis, Differential, Female, Humans, Male, Middle Aged, Postoperative Complications diagnostic imaging, Postoperative Complications etiology, Reoperation, Retrospective Studies, Treatment Outcome, Cholangiopancreatography, Endoscopic Retrograde methods, Cholecystectomy adverse effects, Common Bile Duct injuries, Postoperative Complications surgery, Plastic Surgery Procedures methods
- Abstract
Background: Complete transection of the common bile duct (CBD) is a dramatic and often extremely difficult-to-repair event after surgery. Abdominal biliary fluid collection or jaundice is the initial symptom, and ERCP is the determinant for diagnosis., Objective: To evaluate the safety and efficacy of a combined endoscopic-radiologic technique for the reconstruction of the CBD., Design: Single-center retrospective study., Setting: Tertiary-care center for biliary surgery., Patients: This study involved 22 patients with complete transection of the CBD after cholecystectomy., Intervention: A guidewire is passed in the subhepatic space through the endoscopic approach. A snare loop is advanced from the percutaneous entry site to catch the free end of the wire and then pulled outside the body: a percutaneous biliary-duodenal (PTBD) drainage is put in place. After a new contralateral PTBD, 4 plastic stents are inserted. The stents are removed endoscopically after 8 to 12 months., Main Outcome Measurements: Success of the rendezvous maneuver, patient recovery, and patient mortality., Results: After a mean follow-up period of 4 years, 16 patients are asymptomatic. Two patients are still under treatment, and 4 patients underwent surgery, as was the surgeon's choice., Limitations: Single-center, retrospective study with a small population., Conclusion: Interruption of the biliary tree does not represent an indication for an often-difficult surgical treatment, because the CBD is often thin in the presence of biliary peritonitis. However, the condition can be treated with a rendezvous technique. Surgery can be performed in elective conditions or completely avoided when conservative therapy is selected., (Copyright © 2011 American Society for Gastrointestinal Endoscopy. Published by Mosby, Inc. All rights reserved.)
- Published
- 2011
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40. Selective embolization of thyroid arteries for preresection or palliative treatment of large cervicomediastinal goiters.
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Tartaglia F, Salvatori FM, Russo G, Blasi S, Sgueglia M, Tromba L, and Berni A
- Subjects
- Aged, Female, Goiter diagnostic imaging, Goiter pathology, Humans, Radiography, Embolization, Therapeutic, Goiter therapy, Palliative Care, Thyroid Gland blood supply
- Abstract
Background: The authors have applied the selective embolization of thyroid arteries in the treatment of voluminous cervicomediastinal goiters, especially in patients at high surgical risk or reluctant to undergo surgical intervention and radioiodine therapy., Method: Selective arteriography was used to embolize the thyroid arteries in 2 patients with voluminous hyperfunctioning cervicomediastinal goiters and mediastinal compressive symptoms. The first patient had already undergone unsuccessful radioiodine metabolic therapy and had severe left ventricular insufficiency contraindicating surgery. The second patient, despite having no contraindications, declined surgery and radioiodine metabolic therapy., Results: Radiological embolization markedly reduced the goiters in volume, resolved the compressive symptoms, and also normalized thyroid hyperfunction. The second patient needed a second embolization procedure because the embolized arterial branches had partly recanalized., Conclusion: Selective embolization of thyroid arteries can be successfully used to treat selected patients as a preoperative procedure and as an alternative to thyroid resection. Embolization can be repeated to achieve the required therapeutic aims.
- Published
- 2011
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41. Transjugular intrahepatic portosystemic shunt with expanded-polytetrafuoroethylene-covered stents in non-cirrhotic patients with portal cavernoma.
- Author
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Fanelli F, Angeloni S, Salvatori FM, Marzano C, Boatta E, Merli M, Rossi P, Attili AF, Ridola L, Cerini F, and Riggio O
- Subjects
- Adult, Female, Hemangioma, Cavernous complications, Hemangioma, Cavernous surgery, Humans, Hypertension, Portal etiology, Liver Neoplasms complications, Liver Neoplasms surgery, Male, Middle Aged, Polytetrafluoroethylene, Stents, Thrombosis, Treatment Outcome, Hypertension, Portal surgery, Portal Vein surgery, Portasystemic Shunt, Transjugular Intrahepatic instrumentation, Portasystemic Shunt, Transjugular Intrahepatic methods, Venous Thrombosis surgery
- Abstract
Aims: To evaluate the feasibility and efficacy of Transjugular intrahepatic portosystemic shunt (TIPS) in non-cirrhotic patients with symptomatic portal hypertension secondary to portal cavernoma., Methods: Our cohort includes 13 consecutive patients. Eleven were considered for Transjugular intrahepatic portosystemic shunt placement for complications not manageable by medical/endoscopic treatment and two because of the need of oral anticoagulation in presence of high-risk varices. Expanded-polytetrafluoroethylene-covered stents were used in all., Results: One of the 13 patients was excluded because of a thrombosis of the superior cava and jugular veins. In 10 patients, Transjugular intrahepatic portosystemic shunt was successfully implanted [83.3%; 95% confidence interval: 52-98%]. One patient had an early shunt dysfunction with recurrence of variceal bleeding which required an emergency surgical shunt. Late shunt dysfunction occurred in two patients, successfully treated with angioplasty and re-stenting. Two patients experienced an episode of encephalopathy., Conclusions: Transjugular intrahepatic portosystemic shunt is feasible in most of the patients with portal cavernoma and should be considered in those with severe complications uncontrolled by conventional therapy. The use of Transjugular intrahepatic portosystemic shunt to achieve a lifelong anticoagulation therapy in selected patients with high-risk varices may be another possible indication. These patients should be referred to selected Units with large experience in Transjugular intrahepatic portosystemic shunt placement., (Copyright © 2010 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.)
- Published
- 2011
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42. Chlamydophila pneumoniae infection in patients undergoing carotid artery stent.
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Mancini F, Boatta E, Vescio MF, Fanelli F, Salvatori FM, Passariello R, Cassone A, and Ciervo A
- Subjects
- Aged, Antibodies, Bacterial blood, C-Reactive Protein analysis, Chaperonin 60 immunology, DNA, Bacterial analysis, Female, Humans, Male, Middle Aged, Plaque, Atherosclerotic microbiology, Risk Factors, Carotid Stenosis therapy, Chlamydophila Infections etiology, Chlamydophila pneumoniae, Stents microbiology
- Abstract
Although several reports have correlated Chlamydophila pneumoniae (CP) infection with carotid endarterectomy and coronary stent, no data have been reported on the potential relationship between this pathogen and carotid artery stenting (CAS). Hence, we evaluated 47 subjects, 27 symptomatic and 20 asymptomatic, before CAS intervention and during the follow up, for the presence of CP DNA and anti-CP antibodies, including chlamydial HSP60 (Cp-HSP60). Before stent placement, CP DNA was detected exclusively in symptomatic patients, all of whom were also positive for CP IgG and IgA and 85.7 percent of them also had CP-HSP60 antibodies. At the follow-up, all CP DNA positive and 11 out of the 13 symptomatic patients with Cp-HSP60 antibodies became negatives. In contrast, no change was observed for CP- IgA antibodies. Despite the small number of patients, the present study advocates an important role of CP infection in symptomatic patients with carotid artery disease. Our findings also suggest that stent placement and/or therapy might have a role in favouring resolution of inflammation, though not affecting persistence of CP infection.
- Published
- 2010
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43. Clinical efficacy of transjugular intrahepatic portosystemic shunt created with covered stents with different diameters: results of a randomized controlled trial.
- Author
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Riggio O, Ridola L, Angeloni S, Cerini F, Pasquale C, Attili AF, Fanelli F, Merli M, and Salvatori FM
- Subjects
- Adult, Aged, Ascites etiology, Ascites therapy, Female, Hepatic Encephalopathy epidemiology, Hepatic Encephalopathy etiology, Humans, Hypertension, Portal complications, Hypertension, Portal mortality, Incidence, Liver Cirrhosis complications, Liver Cirrhosis mortality, Male, Middle Aged, Paracentesis, Portasystemic Shunt, Transjugular Intrahepatic methods, Psychometrics, Survival Rate, Treatment Outcome, Hepatic Encephalopathy prevention & control, Hypertension, Portal surgery, Liver Cirrhosis surgery, Portasystemic Shunt, Transjugular Intrahepatic adverse effects, Portasystemic Shunt, Transjugular Intrahepatic instrumentation, Stents
- Abstract
Background & Aims: The incidence of post-TIPS hepatic encephalopathy (HE) could be reduced by using stents with a small diameter. The aim of this study was to compare the incidence of HE and the clinical efficacy of TIPS created with 8- or 10-mm PTFE-covered stents., Methods: Consecutive cirrhotics submitted to TIPS for variceal bleeding or refractory ascites were randomized to receive a 8- or 10-mm covered stent. As recommended by our Ethical Committee, the trial was stopped after the inclusion of 45 patients., Results: The two groups were comparable for age, sex, etiology, and psychometric performance. After TIPS, the portosystemic pressure gradient was significantly higher in the 8-mm stent group (8.9+/-2.7 versus 6.5+/-2.7 mmHg; p=0.007). Consequently, the probability of remaining free of complications due to portal hypertension was significantly higher in the 10-mm than in the 8-mm stent group: 82.9% versus 41.9% at one year; log-rank test, p=0.002. In particular, the persistence of ascites with the need for repeated paracentesis was significantly more frequent in the patients treated with 8-mm stent diameter for refractory ascites (log-rank test, p=0.008). The probability of remaining free of HE was similar in both groups. Cumulative survival rate was similar in both groups., Conclusions: The use of 8-mm diameter stents for TIPS leads to a significantly less efficient control of complications of portal hypertension. HE remains an unsolved major problem after TIPS., (Copyright 2010 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.)
- Published
- 2010
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44. Peripheral and splanchnic indole and oxindole levels in cirrhotic patients: a study on the pathophysiology of hepatic encephalopathy.
- Author
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Riggio O, Mannaioni G, Ridola L, Angeloni S, Merli M, Carlà V, Salvatori FM, and Moroni F
- Subjects
- Aged, Ammonia blood, Female, Hepatic Encephalopathy blood, Hepatic Encephalopathy metabolism, Humans, Indoles metabolism, Liver metabolism, Liver Circulation, Liver Cirrhosis metabolism, Male, Middle Aged, Oxindoles, Portasystemic Shunt, Transjugular Intrahepatic adverse effects, Psychomotor Performance, Splanchnic Circulation, Hepatic Encephalopathy physiopathology, Indoles blood, Liver Cirrhosis blood
- Abstract
Objectives: Intestinal bacteria metabolize tryptophan into indole, which is then further metabolized into oxindole, a sedative compound putatively involved in the pathophysiology of hepatic encephalopathy (HE). The aim of this study was to measure indole and oxindole levels in patients with cirrhosis with or without HE and to establish whether an intestinal production and a hepatic metabolism of these substances exist., Methods: We studied 10 healthy subjects (controls) and 51 cirrhotic patients: 17 without HE, 14 with a minimal HE, 8 with overt HE, and 12 who had undergone a transjugular intrahepatic portosystemic shunt (TIPS) procedure. In the last group, blood was collected from the artery, and the portal and hepatic veins during TIPS construction and from the peripheral veins before, immediately after, and at weekly intervals during the first month after TIPS., Results: Plasma indole levels were significantly higher in patients with overt HE. Oxindole levels were higher in cirrhotics than in controls. Indole and ammonia were significantly correlated (r=0.66). Peripheral and splanchnic determinations showed that indole was produced in the intestine and cleared by the liver, similar to ammonia. TIPS implantation increased both indole and ammonia levels. After TIPS, the psychometric performance worsened in 4 of the 12 patients. The increase in indole plasma concentrations in these four patients was higher than in those who remained stable after undergoing TIPS., Conclusions: Indole correlates with HE and has a significant intestinal production and hepatic extraction; its level increases after TIPS and is related to psychometric performance. These data suggest that indole may be involved in the pathophysiology of HE.
- Published
- 2010
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45. Management of refractory hepatic encephalopathy after insertion of TIPS: long-term results of shunt reduction with hourglass-shaped balloon-expandable stent-graft.
- Author
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Fanelli F, Salvatori FM, Rabuffi P, Boatta E, Riggio O, Lucatelli P, and Passariello R
- Subjects
- Aged, Female, Hepatic Encephalopathy classification, Hepatic Encephalopathy diagnostic imaging, Humans, Male, Middle Aged, Polytetrafluoroethylene, Retrospective Studies, Treatment Outcome, Hepatic Encephalopathy surgery, Portasystemic Shunt, Transjugular Intrahepatic, Radiography, Interventional, Stents
- Abstract
Objective: The purpose of this study was to review the use of an hourglass-shaped expanded polytetrafluoroethylene (ePTFE) stent-graft to reduce transjugular intrahepatic portosystemic shunts in patients with hepatic encephalopathy refractory to conventional medical therapy., Materials and Methods: From January 2000 through December 2008, 189 transjugular intrahepatic portosystemic shunt procedures were performed with self-expanding stent-grafts. After a mean period of 43.4 +/- 57 weeks, hepatic encephalopathy developed in 12 patients and did not respond to conventional medical therapy with lactulose, nonabsorbable antibiotics, and a protein-restricted diet. In all cases, shunt reduction was performed with an hourglass-shaped balloon-expandable ePTFE stent-graft inserted into the original shunt., Results: Technically successful shunt reduction with an immediate increase in portosystemic gradient was achieved in all patients. Symptoms of hepatic encephalopathy disappeared a mean of 22.3 hours (range, 18-26 hours) after the procedure. After a mean follow-up period of 73.9 +/- 61.88 weeks, no recurrence of hepatic encephalopathy was found. One patient (8.3%) needed dilation of the hourglass-shaped stent-graft after 37 weeks because of recurrence of ascites. At the end of the study, five patients (41.6%) were alive in good clinical condition. Four patients (33.3%) died of cardiovascular failure 1, 2, 24, and 96 weeks after the corrective procedure. Eight months after the reduction procedure, one patient (8.3%) underwent orthotopic liver transplantation, which resulted in clinical improvement. Two patients (16.6%) were lost to follow-up 15.6 and 46.8 weeks after the procedure., Conclusion: Shunt reduction with an hourglass-shaped ePTFE balloon-expandable stent-graft seems effective in reducing shunt flow and rapidly improving the patient's clinical condition. With this technique, shunt diameter can be modified on the basis of the patient's clinical condition.
- Published
- 2009
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46. Nonsurgical treatment of staple line leaks after laparoscopic sleeve gastrectomy.
- Author
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Casella G, Soricelli E, Rizzello M, Trentino P, Fiocca F, Fantini A, Salvatori FM, and Basso N
- Subjects
- Adult, Body Mass Index, Clinical Protocols, Esophagogastric Junction, Female, Fibrin Tissue Adhesive, Humans, Male, Middle Aged, Radiography, Surgical Wound Dehiscence diagnostic imaging, Surgical Wound Dehiscence epidemiology, Weight Loss, Gastrectomy methods, Laparoscopy methods, Obesity, Morbid surgery, Surgical Stapling, Surgical Wound Dehiscence therapy
- Abstract
Background: Laparoscopic sleeve gastrectomy (LSG) is gaining popularity as a "per se" bariatric procedure due to its effectiveness on weight loss and comorbidity resolution. The most feared and life-threatening complication after LSG is the staple line leak and its management is still a debated issue. Aim of this paper is to analyze the incidence of leak and the treatment solutions adopted in a consecutive series of 200 LSG., Methods: From October 2002 to November 2008, 200 patients underwent LSG. Nineteen patients (9.5%) had a body mass index (BMI) of >60 kg/m(2). A 48-Fr bougie is used to obtain an 80-120-ml gastric pouch. An oversewing running suture to reinforce the staple line was performed in the last 100 cases. The technique adopted to reinforce the staple line is a running suture taken through and through the complete stomach wall., Results: Staple line leaks occurred in six patients (mean BMI 52.5; mean age 41.6 years). Leak presentation was early in three cases (first, second, and third postoperative (PO) day), late in the remaining three cases (11th, 22nd, and 30th PO day). The most common leak location was at the esophagogastric junction (five cases). Mortality was nihil. Nonoperative management (total parenteral nutrition, proton pump inhibitor, and antibiotics) was adopted in all cases. Percutaneous abdominal drainage was placed in five patients. In one case, a small fistula was successfully treated by endoscopic injection of fibrin glue only. Self-expandable covered stent was used in three cases. Complete healing of leaks was obtained in all patients (mean healing time 71 days)., Conclusion: Nonoperative treatment (percutaneous drainage, endoscopy, stent) is feasible, safe, and effective for staple line leaks in patients undergoing LSG; furthermore, it may avoid more mutilating procedures such as total gastrectomy.
- Published
- 2009
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47. Injection of the iliopsoas muscle with botulinum toxin in camptocormia.
- Author
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Colosimo C and Salvatori FM
- Subjects
- Anti-Dyskinesia Agents administration & dosage, Botulinum Toxins, Type A administration & dosage, Humans, Injections, Intramuscular, Parkinson Disease complications, Posture, Psoas Muscles drug effects, Anti-Dyskinesia Agents therapeutic use, Botulinum Toxins, Type A therapeutic use, Parkinson Disease drug therapy
- Published
- 2009
- Full Text
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48. Anomalous origin and aneurysm of the suprascapular artery: the first case observed.
- Author
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Zardi EM, Bucci F, Zardi DM, Capoano R, Salvatori FM, Tromba L, and Amoroso A
- Abstract
A 45-year-old woman was referred to our department having suddenly developed, 9 months earlier, a pulsating mass on the right supraclavicular fossa and torticollis. Colour Doppler sonography and computed tomographic angiography showed the presence of an aneurysm (21 mm in diameter) of the suprascapular artery that had an anomalous origin from the subclavian artery. Thoracic outlet syndrome was excluded. After selective arteriography, the aneurysm of the suprascapular artery was successfully treated with ethylene-vinyl alcohol polymer (Onyx, MicroTherapeutics, Irvine, California, USA), a liquid embolic agent. The patient was discharged on the first postoperative day in good condition. Control colour Doppler sonography at 1 year confirmed the complete thrombosis of the aneurysm sac.
- Published
- 2009
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49. Incidence, natural history, and risk factors of hepatic encephalopathy after transjugular intrahepatic portosystemic shunt with polytetrafluoroethylene-covered stent grafts.
- Author
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Riggio O, Angeloni S, Salvatori FM, De Santis A, Cerini F, Farcomeni A, Attili AF, and Merli M
- Subjects
- Disease Progression, Female, Humans, Incidence, Male, Middle Aged, Risk Factors, Hepatic Encephalopathy epidemiology, Hepatic Encephalopathy etiology, Liver Cirrhosis complications, Polytetrafluoroethylene adverse effects, Portasystemic Shunt, Transjugular Intrahepatic adverse effects, Stents adverse effects
- Abstract
Background and Aims: The aim of this study was to assess the incidence, natural history, and risk factors of hepatic encephalopathy (HE) after transjugular intrahepatic portosystemic shunt (TIPS) with the new polytetrafluoroethylene (PTFE)-covered stent grafts in cirrhotic patients., Patients and Methods: Seventy-eight cirrhotic patients treated by TIPS with PTFE-covered stent grafts and followed by the same medical team--according to a prospective protocol for diagnostic workup and surveillance strategy--were reviewed. The follow-up was 19.9 +/- 20.6 months., Results: At least one episode of HE occurred in 35 of 78 (44.8%) patients. The probability of remaining free of HE was 53.8% (95% confidence interval [CI] 41.4-66.2] at 1 yr and 50.9% at 2 yr (95% CI 38.2-63.8%). The total number of HE episodes was 89. Fifty-five percent of the episodes were grades III-IV. The occurrence of HE tended to be constant during the follow-up, probably because of the very low incidence of shunt dysfunction (13.6% at 2 yr). Moreover, in six patients, a refractory HE required the reduction of the shunt diameter. One patient died due to variceal bleeding after this procedure. At a multivariate analysis, an older age, high creatinine levels, and low serum sodium and low albumin values were shown to be independent factors for the occurrence of HE. Serum creatinine level was the only variable related to the development of refractory HE at the logistic multivariate analysis., Conclusions: HE after TIPS with PTFE-covered stent grafts is frequent; its incidence is not confined to the first post-TIPS period, but it has the tendency to be frequent over time. Refractory HE occurred in 8% of patients and may be successfully managed by reducing the stent diameter. The selection of patients undergoing TIPS placement should be very accurate, especially for those subjects with abnormal creatinine level.
- Published
- 2008
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50. Minimally invasive treatment of benign complete stenosis of colorectal anastomosis.
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Donatelli G, Ceci V, Cereatti F, Bruni A, Salvatori FM, Minervini S, and Fiocca F
- Subjects
- Adult, Aged, Colonoscopy, Constriction, Pathologic therapy, Female, Humans, Male, Anastomosis, Surgical adverse effects, Catheterization, Colectomy adverse effects, Colon surgery, Rectum surgery, Stents
- Published
- 2008
- Full Text
- View/download PDF
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