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A roll-to-roll (R2R) manufacturing system has been considered the most suitable candidate for commercializing flexible electronic devices owing to its large-area and mass-production characteristics. A high-precision register control should be ensured when fabricating devices using the R2R system. Contrary to conventional manufacturing systems that are applied to rigid materials, the control target in an R2R system is a flexible film that can lead to a substantial time delay in the control response and degrade the register control performance. This paper proposes a novel control scheme, namely response acceleration input, to provide a rapid response in the register control of flexible substrates. Mathematical models to achieve the proposed scheme were developed. A register control system based on the developed models was designed, followed by experimental verifications using an industrial-scale R2R system. The results show that the register error is successively controlled below 10 m with a high yield of over 80% for 1800 s. We believe that the proposed control strategy can realize a high-precision register control below 10 m in industrial-scale R2R manufacturing systems, thus enabling the commercialization of multilayered, flexible electronic devices.

Первинні імунодефіцити (ПІД) являють собою групу рідкісних вроджених захворювань системи імунітету. Виявлення ПІД, підрахунок їх кількості й ідентифікація нозологічних форм є надзвичайно актуальною проблемою педіатрії, оскільки це важливо для розробки заходів щодо діагностики та лікування. Метою роботи було вивчення частоти ПІД в Україні та їх нозологічних форм шляхом створення реєстру пацієнтів. У 27 адміністративних центрах України була зібрана інформація про всіх пацієнтів із ПІД, діагностованих протягом 1995–2014 рр. На початок 2015 р. у реєстр включено 814 пацієнтів, із них 684 — живі, серед яких 561 дітина та 123 пацієнти віком понад 18 років. Мінімальна частота ПІД становить 1,23 живого пацієнта на 100 тис. населення, мінімальна частота народження дитини із ПІД — 9,94 на 100 тис. народжених живими. Структура ПІД за ланкою ураження імунної системи в Україні близька до структури у світі, основні групи ПІД представлені 39 нозологічними формами. Отримані дані свідчать про недостатнє виявлення ПІД в Україні, тому залишається актуальним питання підвищення настороженості лікарів різних спеціальностей стосовно ПІД і своєчасного направлення пацієнтів на консультацію до дитячого імунолога.

Background This study developed, calibrated and evaluated a machine learning (ML) classifier designed to reduce study identification workload in maintaining the Cochrane COVID-19 Study Register (CCSR), a continuously updated register of COVID-19 research studies. Methods A ML classifier for retrieving COVID-19 research studies (the ‘Cochrane COVID-19 Study Classifier’) was developed using a data set of title-abstract records ‘included’ in, or ‘excluded’ from, the CCSR up to 18th October 2020, manually labelled by information and data curation specialists or the Cochrane Crowd. The classifier was then calibrated using a second data set of similar records ‘included’ in, or ‘excluded’ from, the CCSR between October 19 and December 2, 2020, aiming for 99% recall. Finally, the calibrated classifier was evaluated using a third data set of similar records ‘included’ in, or ‘excluded’ from, the CCSR between the 4th and 19th of January 2021. Results The Cochrane COVID-19 Study Classifier was trained using 59,513 records (20,878 of which were ‘included’ in the CCSR). A classification threshold was set using 16,123 calibration records (6005 of which were ‘included’ in the CCSR) and the classifier had a precision of 0.52 in this data set at the target threshold recall >0.99. The final, calibrated COVID-19 classifier correctly retrieved 2285 (98.9%) of 2310 eligible records but missed 25 (1%), with a precision of 0.638 and a net screening workload reduction of 24.1% (1113 records correctly excluded). Conclusions The Cochrane COVID-19 Study Classifier reduces manual screening workload for identifying COVID-19 research studies, with a very low and acceptable risk of missing eligible studies. It is now deployed in the live study identification workflow for the Cochrane COVID-19 Study Register.

In recent years, interpreting has becoming increasingly important due to the expanded cooperation and globalization between different countries. Interpretation applies register and varies with it. Thus, the author intends to explore the relationship between source and target language’s register in interpreting and compares different interpretations into the target language according to the changes of register. The author reclassifies three categories of interpreting cases and analyzes them case by case, which show different relationships between source and target language’s register. Thus, the relationship between register in the source and target language should be analyzed from the overall style of the interpretation case and the three parameters: field, tenor and mode.

This study applies additive Multi-Dimensional Analysis (MDA) (Biber 1988) to explore the linguistic characteristics of ‘school English’ or ‘textbook English’. It seeks to find out how text registers commonly featured in English as a Foreign Language (EFL) textbooks differ from comparable registers found outside the EFL classroom. To this end, a Textbook English Corpus (TEC) of 43 coursebooks used in European schools is mobilised. The texts from six textbook register subcorpora and three target language corpora are mapped onto Biber’s (1998) ‘Involved vs. Informational’ dimension of General English. Register accounts for 63% of the variance in these dimension scores in the TEC. Additional factors such as textbook level, series and country of publication/use only play a marginal role in mediating textbook register variation. Textbook dialogues score considerably lower than the Spoken BNC2014, whereas Textbook Fiction scores closest to its corresponding reference Youth Fiction Corpus. Pedagogical and methodological implications are discussed.

Актуальность. Проведение сравнительного анализа репрезентативных региональных данных по уровню диагностики на госпитальном этапе ведения инсульта за определенный период времени и между различными лечебными учреждениями позволяет корректно сформировать комплекс лечебно-профилактических мероприятий и разработать последовательные рекомендации по их улучшению. Цель исследования: оценить динамику показателей качества клинико-аппаратной диагностики инсульта за период 2017–2019 гг. и провести их сравнительный анализ между исследуемыми лечебно-профилактическими учреждениями. Материалы и методы. По данным историй болезни выполнен сравнительный анализ уровня организации клинико-аппаратной диагностики в коммунальном некоммерческом предприятии «Винницкая областная клиническая психоневрологическая больница им. акад. А.И. Ющенко Винницкого областного совета» (ВОКПНБ) и Винницкой городской клинической больнице скорой медицинской помощи (ВГКБСМП) в 2017–2019 гг. Статистическая обработка результатов выполнена с помощью статистического пакета «Statistica 5.5». Результаты. Установлены достоверные различия в процентной доле пациентов ВОКПНБ и ВГКБСМП, которым на госпитальном этапе проведены оценка степени тяжести инсульта по Шкале инсульта Национальных институтов здравоохранения США, нейровизуализация в первые часы заболевания, ультразвуковое исследование сосудов шеи, скрининг на предмет фибрилляции предсердий и дисфагии, консультация логопеда и физиотерапевта. В каждом медицинском учреждении отмечена положительная динамика за три года по факту проведения всех диагностических мероприятий и процедур. Выводы. Результаты исследования подтвердили адекватность изученных индикаторов качества и целесообразности дальнейшего внедрения метода госпитального регистра в других регионах Украины для оценки и контроля качества медицинской помощи, включая анализ эффективности новых технологий.

The overall aim of this study was to examine the different self-reported students’ socioeconomic status (SES) measures in the Trends in Mathematics and Science Study (TIMSS) in comparison to national SES measures obtained from Swedish official registers. A further aim was to determine if the same conclusions could be drawn if different student measures were used to define SES when modelling the students’ TIMSS mathematics achievement. The overall results showed that the choice of SES measures matters. The home educational resource index and books at home from the TIMSS data base were good indicators of SES. We conclude that when one has access to SES information from official registers it is recommended to use it because these measures have less missing information compared with the TIMSS variables.

The paper analyzes the system of state authorities that register civil status acts. The purpose of this research is to study the powers of public authorities in the field of state registration of civil status acts and to identify some problems of legislation and law enforcement in this area. In the course of the research, general and special methods of scientific cognition are used: historical, comparative, formal-legal, dialectical, etc. Results: it is concluded the system of authorities that register civil status acts are included in the state information system of civil status records as one of its components, and it is also shown that it is inappropriate to expand the scope of authorities whose powers include state registration of civil status acts.

Background and Purpose: Previous studies of stroke management and outcome in Sweden have revealed differences between men and women. We aimed to analyze if differences in stroke incidence, care, and outcome have altered over time. Methods: All stroke events registered in the Swedish Stroke Register 2005 to 2018 were included. Background variables and treatment were collected during the acute hospital stay. Survival data were obtained from the national cause of death register by individual linkage. We used unadjusted proportions and estimated age-adjusted marginal means, using a generalized linear model, to present outcome. Results: We identified 335 183 stroke events and a decreasing incidence in men and women 2005 to 2018. Men were on average younger than women (73.3 versus 78.1 years) at stroke onset. The age-adjusted proportion of reperfusion therapy 2005 to 2018 increased more rapidly in women than in men (2.3%–15.1% in men versus 1.4%–16.9% in women), but in 2018, women still had a lower probability of receiving thrombolysis within 30 minutes. Among patients with atrial fibrillation, oral anticoagulants at discharge increased more rapidly in women (31.2%–78.6% in men versus 26.7%–81.9% in women). Statins remained higher in men (36.9%–83.7% in men versus 32.3%–81.2% in women). Men had better functional outcome and survival after stroke. After adjustment for women’s higher age, more severe strokes, and background characteristics, the absolute difference in functional outcome was Conclusions: Stroke incidence, care, and outcome show continuous improvements in Sweden, and previously reported differences between men and women become less evident. More severe strokes and older age in women at stroke onset are explanations to persisting differences.

The data on the assessment of the dynamics of forested lands of the Republic of Belarus are presented. The characteristics of the forest fund for the period 1994–2019 are presented. Based on the materials of the provisions of international treaties, documents adopted within the framework of the implementation of the UN Framework Convention on Climate Change at the international and national levels, including the Paris Agreement, the provisions of regulatory legal acts of the Republic of Belarus, the results of scientific research, information from the Ministry of Forestry, according to the data of the State Forest Cadastre, an assessment of greenhouse gases in the forest fund of the Republic of Belarus was carried out. CO2 emissions and sinks from forestry have been calculated in accordance with the IPCC Guidelines for National Greenhouse Gas Inventories using the stock-difference method. It was found that as a result of purposeful work on reforestation and reforestation over a 26-year period, a positive dynamics of the forest fund was achieved in the Republic of Belarus: the forested area increased by 919,6 thousand ha from 7360,7 thousand ha to 8280,3 thousand ha; the forest cover of the territory of the republic increased by 4,3 % and reached 39,9 %; the total standing timber stock increased by 739,5 million m3 from 1092,3 to 1831,8 million m3 (including in mature and over-mature stands — by 300,3 million m3 and amounted to 348,8 million m3); the reserve per hectare of forested land increased by 72,8 m3 and amounted to 221,2 m3/ha; the stock of mature and over-mature stands increased by an average of 52,6 m3 and reached 273,9 m3/ha.

Roll-to-roll (R2R) printing systems provide a continuous process of thin, flexible material (called web) through printing cylinders, where the required patterns are printed on the web. Tension fluctuation caused by the upstream register control quantity may lead to the downstream register errors. Thus, it is a challenge to develop a register control algorithm to remove the couplings among the angular velocity, tension fluctuation, and register error. In this article, the register error is defined as the marks position misalignment between the first and the current printing unit. Based on the definition, a mathematical model of registration is derived. Based on the model, a fully decoupled proportional-derivative (FDPD) control algorithm is proposed to completely remove the coupling between the upstream register control quantity and the downstream register error. Simulations and experiments are carried out to demonstrate the effectiveness of the proposed control algorithm. Compared with the other compensation control methods, FDPD is a complete decoupling control method, which can control the register errors of all downstream printing units (more than seven printing units) within $\pm 0.05$ mm, even if the upstream printing unit has a 3 mm register error. Decoupling formula included in the FDPD control is a first-order compensation formula, which is easy to implement in the actual industry. Furthermore, the proposed FDPD can deal with the situation where two adjacent gravure cylinders have different web lengths, which is not taken into account by other control methods.

The comparative analysis of the regulatory framework of the rules of the Russian river register (PRR) and the Russian maritime register of shipping (PMR) on the design and strength of ships on underwater wings (SEC) showed a significant difference between the methodologies of these rules. In this regard, a comparative analysis of the rules is possible only by performing numerical calculations for specific vessels. This paper presents the results of calculations for three SEC models. It is shown that with some extrapolation of the dependences given in the PRR, the values ​​of the calculated values ​​of bending moments for SEC, intended for operation on the excitement of h3%> 2.0 m, can be obtained from the PMR. For more weak wave modes Settlements. The existing approach to the pro-willer of the strength of the SEC wing devices should be recognized obsolete. It is necessary to either upgrade the PRR, taking into account modern advances in the field of hydrodynami, or allow the use of modern software complexes for computers based on numerical methods for solving hydrodynamic problems.

Aim. To study the features of clinical and anamnestic characteristics and treatment of patients with hypertriglyceridemia (HTG) using the data of the lipid control center of Kemerovo.Methods. The single-center retrospective study is based on the data of patients dynamic observation (n = 100) in the Dyslipidemia Registry of Kuzbass in 2019. A comparative analysis of clinical and anamnestic characteristics, lipidogram parameters and therapy was performed at the time when the patients were included in the study and after 6–12 months in patients with HTG (the criterion was the level of triglycerides (TG) above 1.69 mmol/L) and in patients without it. Indications for consulting a lipidologist were high cholesterol (levels of total cholesterol (TC) ˃7.5 mmol/L or low-density lipoprotein cholesterol ˃4.9 mmol/L or TG˃5 mmol/L), requirement of the high dose and/or combination therapy of lipid-lowering drugs; medical history of cardiovascular diseases and/or revascularization of vascular bed in patients under 55 years of age; suspected intolerance to lipid-lowering therapy due to the developed side effects; the issue of lipid-lowering therapy in complex clinical situations.Results. Among the patients who visited a lipidologist in 2019, mixed hypertriglyceridemia was noted in 56 (56%) of cases, while 44 (44%) patients had other lipid metabolism disorders without increased levels of TG. A distinctive feature of patients with mixed hypertriglyceridemia is the lower incidence of myocardial infarctions (p = 0.029) and lower number of coronary stents (p = 0.018) in the medical history, despite the initially higher levels of TC (p = 0.005) and TG (p = 0.000). According to the results of 6–12 months observation, a significant decrease in TC (p = 0.001) and TG (p = 0.044) levels during the lipid-lowering therapy was revealed due to the addition of fenofibrate (p = 0.000) to all groups of patients who were monitored by a lipidologist.Conclusion. The patients with dyslipidemia and HTG are a complex category of patients who require combined lipid-lowering therapy, which can only be prescribed by a lipidologist.

Antônio Madureira é um compositor e violonista brasileiro. Embora tenha obras musicais dos mais diversos estilos, seu nome é frequentemente associado ao Movimento Armorial. Este foi um movimento liderado por Ariano Suassuna. O objetivo do Movimento Armorial foi criar uma arte erudita autenticamente brasileira, baseada nas culturas populares do Nordeste do Brasil. Na música, o grupo mais significativo do Movimento Armorial foi o Quinteto Armorial, que nasceu do encontro entre Ariano Suassuna e Antônio Madureira. Por conta da importância do Antônio Madureira para a música armorial, em 2017 eu o entrevistei, para uma pesquisa sobre as influências armoriais na música de Pernambuco. Nesse texto apresentamos esta entrevista, como um meio de registrá-la e também para que outros/as/es pesquisadores/as possam utilizá-la.

Quality, exegetical writing can be constrained when students marginalize poetic ways of thinking and replace them with carefully edited accounts that reshape the role and nature of emotional response. In the pursuit of rational, theoretically groomed accounts of practice, they can sometimes end up misrepresenting the embodied nature of their inquiries. Considering burgeoning research into poetic inquiry (PI) in the social sciences, this article employs a case study of five doctoral graduates in art and design who have articulated the role of poetic thinking in their creative practice theses. In addition to offering illustrations of how practice-led researchers use PI, the examples demonstrate ways in which poetic approaches can be employed to enhance communicative clarity beyond the constraints of conventional academic writing. Specifically, the examples demonstrate how poetic writing is used to process and articulate indigenous knowledge, enhance embodied thinking and inquiry and deepen levels of reflection and understanding. Such uses can cause a researcher to view the world differently and by extension, expand the nature of what it means to conduct research. In discussing the nature of poetic writing, the article considers three distinct profiles: exegetical writing employed when the nature of the practice is poetic; poetic writing that draws on indigenous approaches to scholarship and poetic writing used as a method for reflection.

Online commerce websites often request users to register in the online shopping process. Recognizing the challenges of user registration, many websites opt to delay their registration request until the end of the conversion funnel (i.e., ex post registration request). A new study in Information Systems Research explores an alternative approach by asking users to register with the website at the beginning of their shopping journey (i.e., ex ante registration request). The authors of the study, Ni Huang (University of Houston), Probal Mojumder (University of Southern California), Tianshu Sun (University of Southern California), Jinchi Lv (University of Southern California), and Joseph M. Golden (Collage.com), show that the ex ante request leads to an increased probability of user registration. Furthermore, the ex ante request leads to considerable increases in customer purchases in the long run and does not significantly influence sales in the short run. Further investigation into the long-term and short-term effects provides suggestive evidence on several potential mechanisms, such as firm-initiated interaction (e.g., email marketing campaigns) and screening of low-interest users (i.e., users with low initial valuations of the website and in a potentially disengaged state). This study provides managerial implications on the design of user-registration systems in e-commerce websites.

Classical singers use nasal consonants as “resonance exercises,” and experimental results have shown that singers may use some velopharyngeal opening (VPO), most often in [a:] and more seldom in [i:] or [u:]. In particular, male singers have been found to increase VPO as pitch rises toward register change frequencies (passaggi). Laryngoscopic findings have shown that some VPO stabilizes vocal fold vibration; the effect is related to positive reactance. This study investigates the effects of VPO on vocal tract (VT) reactance over the range of fundamental frequencies (f0) used in singing using a computerized tomography-based finite element model of the VT and nose of a female. According to the results, by raising the lowest VT resonances, the VPO increased the VT reactance in the frequency ranges 207–359 Hz for [i:], 265–411 Hz for [u:], and 500–611 Hz for [a:], depending on the VPO size (full or half VPO). These frequency ranges are close to the first and second passaggio of a female singer. The change may have an especially practical stabilizing effect for [a:], which is otherwise characterized by very large changes in VT reactance and negative reactance at the second passaggio.

Legislation on industrial safety in the Republic of Uzbekistan appeared with the adoption of the Law «On industrial safety of hazardous production facilities». This law formulates the industrial safety requirements that must be met at all stages of the operation of a hazardous production facility, from its design, location and ending with decommissioning. In accordance with Article 5 of this Law, hazardous production facilities are subject to mandatory registration in the state register by a specially authorized state body in the field of industrial safety. To meet the requirements for the implementation of the law, the State Committee for Industrial Safety adopted the relevant orders on organizing the maintenance of the state register. The article deals with the actual problem of improving the system of the Unified State Register of hazardous production facilities of the Republic of Uzbekistan. The program was developed that contains the information about hazardous production facilities, the registration, and the further maintenance of the system of the Unified State Register of hazardous production facilities are conducted. The program is implemented in the modern unified electronic register State Register of Hazardous production facilities of the Republic of Uzbekistan. The specified electronic register is introduced into the electronic document management program PEGAS of the State Committee for Industrial Safety. Maintaining the Unified State Register and accounting of hazardous production facilities, as well as the accumulation, analysis, and storage of the systematized information about operating facilities, organizations and individual entrepreneurs operating these facilities, provide efficient management and control over hazardous production facilities.

The aim of this study was to evaluate chronic pain 1 year after surgery, and risk factors for chronic pain after groin hernia repair in women.Groin hernia surgery in women is less frequently studied than in men. Chronic pain is common after groin hernia surgery and remains an important area with room for improvement. Previous studies are small or inconclusive. Guidelines recommend timely repair of all female groin hernias.From the Swedish Hernia Register 4021 female and 37,542 male patients operated between September 1, 2012 and August 30, 2017 responded to a patient-reported outcome questionnaire (response rate 70.0%) 1 year after primary groin hernia surgery. Multivariable analysis was performed to compare chronic postoperative pain in women with men as a control group, and to evaluate risk factors for chronic pain in women.Among women operated for groin hernia, 18% suffered chronic postoperative pain. The risk for chronic pain was significantly higher for women [odds ratio 1.3 (95% confidence interval 1.16-1.46). Three risk factors for chronic pain in women were found: high body mass index, high American Society of Anesthesiologists classification, and femoral hernia. No differences in chronic pain in women were seen when comparing surgical methods or emergency versus elective surgery.Almost one-fifth of women suffered of chronic pain affecting daily activity after groin hernia repair. Chronic pain was more common for women than men. In view of the high-rate chronic postoperative pain, further research on management strategies in female groin hernia is warranted.

In this work we have concentrated our attention to a High Speed 4-bit Bidirectional Register with Parallel Loading counting on the principle of threshold logic gates (TLG). After determining the number of logic gates and other circuits needed to complete the desired circuit for our work, we implement some gates and circuits made up of tunnel junctions and capacitances. Some multi-inputs (greater than two) are designed or implemented with the assistance of modified version of the generic multi-input TLG. The types of gates suitable for the implementing the bidirectional Register are 3-input AND, 3-input NAND and 4-input OR gates, in addition an inverter and a more complex circuits like 4:1 Multiplexer are the part and parcel of the desired device. With the help of a 3-input AND gate and a 4-input OR gate, a 4:1 Multiplexer is built. By using the 3-input NAND gate a memory element – D Flip-flop is constructed. At last 4 number of 4:1 Multiplexers and another four number of D Flip-flops are combined in a parallel pattern to implement a 4-bit Bidirectional Register with Parallel Loading. Each component is made after analyzing their corresponding threshold linear equations. After constructing the threshold circuits, again they are formed by using the parameters as capacitors, tunnel junctions with their internal resistances. All the circuit, which are constructed, are verified by simulation with the help of SIMON and the result obtained are investigated and found that they are matched with the theoretical results. For comparing the fastness of our circuit with the CMOS-based or single electron transistor (SET) based circuit, the processing delays of all gates/ circuits are determined. How much power they consume are measured as well. Comparing the delays of CMOS-based and SET based circuit with the TLG based circuit we have decided that our 4-bit Bidirectional Register with Parallel Loading is speedier.

Examination questions need to be sufficiently novel if they are to be effective as measurement instruments. Novelty, however, presupposes creativity, suggesting that question writing is, or should ...

Background. To reduce the number of osteoporotic fractures in the world in recent years, — Fracture Liaison Service has been created. Since 2019, the development of a register of patients included in the Secondary Fracture Prevention named «Prometheus» has begun in Russia.Materials and methods. An information system for storing, searching and processing information has been created, and a registration card has been developed. Six FLS participate in the register management. As of 10.03.2021, data on 387 patients were introduced in the register.Results. Among the included patients, 46.25% received a fracture of the proximal femur, 20.41% — of the vertebral bodies and 16.80% of the proximal humerus, the rest had fractures of other localizations. The risk of fractures was assessed in all patients. A high risk of major osteoporotic fractures according to FRAX was determined in 160 (43.24%) people. Two-energy X-ray absorptiometry (DXA) was performed in 152 (39.28%) patients, and osteoporosis was detected in 103 (67.76%), osteopenia — in 42 (27.63%) patients. The risk of falls was assessed in 100% of the included patients, and the risk of falls was determined to be high in 343 (88.63%) patients. Evaluation of various laboratory parameters to find the causes of secondary osteoporosis was performed in most patients. After consultation with the FLS doctor, anti-osteoporotic drugs were prescribed to 241 (64.27%) people. Among the rest, 70 (52.24%) patients had contra-indications and 31 (23.13%) people needed further examination.Conclusions. Thus, the use of the register allows you to evaluate all the main sections of the organization of assistance within the FLS and compare them with international standards to identify «gaps» and improve the work of the service.

This study presents a register analysis of pop lyrics. To this end, it applies multi-dimensional register analysis to empirically test claims regarding the allegedly conversational nature of pop lyrics. It thus follows broader calls for the linguistic exploration of performed language as represented in non-canonical pop culture registers. This text-linguistic investigation relies on a corpus of contemporary pop lyrics and uses the Multidimensional Analysis Tagger ( Nini, 2018 ), software that replicates Biber's (1988) tagger, to identify register features to contrast lyrics with other varieties of text. In addition, the n-gram and keyword functionalities of a concordancer are used for establishing register markers and style features to identify characteristic properties of pop lyrics. In line with earlier claims, it becomes apparent that pop lyrics indeed carry some conversational force despite situational factors being indicative of planned and performed production. Furthermore, this analysis identifies additional features that are highly distinctive of pop lyrics ( versus general conversation), and is suggestive of the special status of this register on the speech-writing continuum.

Introduction The Cochrane COVID‐19 Study Register (CCSR) is a public, continually updated database of COVID‐19 study references. The aim of this study‐based register is to support rapid and living evidence synthesis, including an evidence ecosystem of COVID‐19 research (CEOsys). In November and December 2020 we conducted an evaluation of the CCSR for CEOsys, measured its performance and identified areas for improvement. Methods For the evaluation we generated a purposive sample of 286 studies from 20 reviews to calculate the CCSR's comprehensiveness (sensitivity), accuracy (correctly classified and linked studies) and currency (time to publish and process references). Results Our sample showed that the CCSR had an overall comprehensiveness of 77.2%, with the highest coverage for interventional studies (94.4%). The study register had 100% coverage for trial registry records, 86.5% for journal articles and 52.4% for preprints. 98.3% of references were correctly classified with regard to study type, and 93.4% with regard to study aim. 89% of studies were correctly linked. 81.4% of references were published to the register in under 30 days, with 0.5 day (median) for trial registry records, 2 days for journal articles and 56 days for preprints. Conclusion The CCSR had high comprehensiveness, accurate study classifications and short publishing times for journal articles and trial registry records in the sample. We identified that coverage and publishing time for preprints needed improvement. Finally, the evaluation illustrated the value of a study‐based register for identifying additional study references for analysis in evidence synthesis.

PurposeThe purpose of this study is to consider how a local government authority may present a tree asset register of street trees for the decision-making of the authority's stakeholders.Design/methodology/approachUsing the tenets of population density theory, urban form theory and social stratification theory, the approach of the study is to develop a tree asset register in a local government authority's setting that could be modelled using many different attributes to derive important information for decision-making purposes.FindingsTree asset registers represent a critical tool in managing street trees across local government authorities.Research limitations/implicationsAlthough the efficacy of an asset tree register may be curtailed by lack of internal audit or yearly updates, the practical consequence of an asset tree register is that local administrators may use the register to gather summarised, organised and parsimonious measures of a wide range of environmental, historical, cultural, aesthetic and scientific values of street trees.Practical implicationsTree asset registers affords ratepayers, developers, tree managers and valuers a technology to plan, coordinate and manage street trees to support ecosystem services.Social implicationsAsset tree registers offer planners a means to bring about sustainable change management.Originality/valueThe originality of the study rests in introducing tree registers as a means to meet diverse strategies for street tree management by interested stakeholders.

The article examines the emerging trends in the transition to the digital format of the domestic education system, shows the importance of the digital model of education for Russian society. The author identifies the role of the register as an information and digital tool, a technical and legal means of ensuring the process of creating and implementing a digital educational environment, and identifies positive opportunities for using distributed registry technology (blockchain) for the Russian education system.

Purpose: To evaluate the proportion and reasons for ineligibility to re-register for extended health insurance at 5 years in patients diagnosed with neovascular age-related macular degeneration (AMD) and registered for extended health insurance. Methods: This retrospective study was performed in patients diagnosed with neovascular AMD and registered for extended health insurance with follow-up for at least 5 years. The criteria for re-registration for extended health insurance were determined along with the ineligibility for re-registration. Results: In total, 263 patients were included in the analysis. Of these, 148 (56.3%) did not satisfy the criteria for re-registration. No active treatment was performed in 98 patients during the last 6 months of the study period (no recurrence, 51 patients; additional treatment was not considered beneficial due to retinal damage even without disciform scar formation, 44 patients). Macular disciform scar formation was noted in 50 patients (33.8%). Older age (p = 0.013), poor visual acuity (p = 0.004), and retinal angiomatous proliferation (p < 0.001) were associated with ineligibility for re-registration due to severe retinal damage. Conclusions: Among the patients who were initially registered for extended health insurance, 56.3% failed to satisfy the re-registration criteria. The primary reason was advanced retinal damage. The results of this study provide useful information for patient education and to establish long-term treatment strategies.

This paper presents an assessment of the criteria for setting the maximum amount of compensation given to a property developer when a buyer breaches their contractual obligations according to the law of the Interim Real Property Register in the Emirate of Dubai. The register gives the developer the power to deduct a certain percentage of the amount paid to them by the buyer, without the need to resort to justice or arbitration. Such a power is one of certain exceptional powers granted to the developer under this law to encourage property investment in Dubai. This research aims to define the type of compensation that the property developer deserves, as well as present the criteria for the maximum amount of compensation and an evaluation of them. This was achieved by analyzing Article 11 of the mentioned law for accuracy and fairness on this issue, and its success in balancing the conflicting interests of both parties. One key result found was that the legislator had not succeeded in balancing the two parties of the off-plan sale. It is strongly recommended that the legislator abolish the three criteria on the maximum amount of compensation and adopt alternative criteria.

It would be natural to suppose that once a trade mark has been expunged from the trade marks register it would cease to have legal force or effect. For many years this was indeed the position in British Commonwealth countries. However, the New Zealand Supreme Court has recently held that a trade mark whose registration has been revoked can still block a subsequent application for registration in certain circumstances. In so doing the New Zealand Supreme Court followed an earlier decision of the Singapore Court of Appeal that was to much the same effect. This article argues that these decisions are problematic on policy grounds and rest on faulty doctrinal premises. It is important to recognise these issues now, not least because there is a danger that this approach may spread to other jurisdictions, including the EU, Hong Kong, and the UK.

Revised edition of an Arsinoite tax register of the second/third century.

Rational and long-term planning and sustainable mineral resources management is of strategic importance in Europe’s efforts to secure the self-supply of mineral raw materials. European mineral data is organized and accessible within the pan-European Minerals Intelligence Network. Most EU countries are part of this network, while the West Balkan region presents a gap in this regard. A common West Balkan mineral register needs to be established in order to close the gap and bring the area closer to the EU market. Including the region into the network would provide new opportunities to local industry and improve mineral management at the national and regional level. In this context, the Geological Survey of Slovenia is working in cooperation with numerous partners and stakeholders in different projects within the framework of European initiatives and programs. We collected and properly organized relevant data on minerals in the region according to the INSPIRE Directive. This paper describes the creation of the West Balkan Mineral Register of primary raw materials, and its content.

Penelitian ini bertujuan untuk mendeskripsikan fenomena pemakaian bahasa di masa pandemi Covid-19 dalam variasi register berbagai bidang media masa online. Penelitian ini menggunakan metodepenelitian deskriptif kualitatif dengan tinjauan sosiolinguistik. Data berupa kata dan kalimat yang terdapatdi berbagai teks media masa online. Sumber data diperoleh dari media masa online baik media masalokal dan nasional. Validitas data atau uji keabsahan data dilakukan dengan menggunakan triangulasiteori, terkait teori register. Teknik yang digunakan yaitu simak, catat dan tangkapan layar. Teknikanalisis data yang digunakan menggunakan metode padan intralingual dan ekstralingual. Berdasarkan hasil analisis yang telah dilakukan maka ditemukan data berupa bentuk dan fungsi register di mediamassa online saat pandemi Covid-19. Bentuk tersebut meliputi, 1) register bentuk satuan lingual; 2)register selingkung terbuka; 3) register selingkung tertutup; 4) register berdasarkan varian medsos;dan 5) perubahan istilah. Serta fungsi penggunaan register yang meliputi; 1) fungsi instrumental; 2)fungsi regulasitoris; dan 3) fungsi representasional. Kata Kunc i: register, pandemi Covid-19, media masa online Abstract This study aims to describe the phenomena of language use during the co-19 pandemic invarious registers of various fields of online media. This study uses descriptive qualitativeresearch methods with a sociolinguistic review. Data in the form of words and sentencescontained in various online media texts. Data sources were obtained from online media bothlocal and national mass media. Data validity using tirianggulasi theory, related to registertheory. The technique used is listen, note and screenshot. The data analysis technique used isthe intralingual and extralingual equivalent method. Based on the results of the analysis that has been done, it is found the data in the form and function of registers in the online massmedia during the co-19 pandemic. These forms include, 1) lingual unit register forms; 2)open environment register; 3) closed environment register; 4) registers based on social mediavariants; and 5) changes in terms. As well as the function of using registers which include;1) instrumental function; 2) regulatory function; and 3) representational functions. Keywords : registers, covid-19 pandemic, online media

The results of comparison of personal dosimeters included in the State Fund of Metrology of Russian Federation are presented.

Настоящая статья является третьей из цикла статей, посвященных корректировке кодекса ИМО по остойчивости в части ограничений продольной качки. В ней рассмотрены подходы к ограничениям по погоде из условий, возникающих при продольной качке для судов различных типов и предложены критерии оценки этих явлений на нерегулярном волнении разной интенсивности. На основании выполненных систематических расчетов продольной качки на нерегулярном волнении получены зависимости вероятности слеминга и оголения винта от скорости и интенсивности волнения для транспортных судов. Полученные формулы позволяют оценить указанные показатели мореходности. При этом ставится цель расширения нормативной базы для обоснованного назначения эксплуатационных ограничений по погоде и району плавания судов при совершенствовании Правил Российского Морского Регист­ра Судоходства на основе общего подхода к нормированию мореходности, со­гласующегося с методикой разработки новой Международной конвенции о гру­зовой марке 2000. Предлагаемый подход к определению дополнительных критериев мореходности для оценки эксплуатационных ограничений судов по погоде из условий мореходности может быть использован на практике для совершенст­вования нормативных требований Регистра. This article is the third in a series of articles devoted to the adjustment of the IMO stability code in terms of pitching limitations. It considers approaches to weather restrictions based on the conditions arising during pitching for ships of various types and proposes criteria for assessing these phenomena on irregular waves of different intensities. Based on the performed systematic calculations of pitching on irregular waves, the dependences of the probability of slamming and propeller bareness on the speed and intensity of waves for transport vessels were obtained. The formulas obtained make it possible to evaluate the indicated seaworthiness indicators. At the same time, the goal is to expand the regulatory framework for the justified assignment of operational restrictions on the weather and the area of navigation of ships while improving the Rules of the Russian Maritime Register of Shipping on the basis of a general approach to the regulation of seaworthiness, consistent with the methodology for the development of a new International Convention on Load Mark 2000 The proposed approach to the definition of additional seaworthiness criteria for assessing the operational limitations of ships by weather based on seaworthiness conditions can be used in practice to improve the regulatory requirements of the Register.

The service process is the key phase in any queue system applied to business and industry operations. The service process in shops is defined as the payment process at the cash register. The service process consists of two elements or sub-processes: the waiting in the queue to the cash register as well as the payment processing (scanning the goods, giving receipts to customers, etc). Analysis of burstiness as the indicator of the service process has been well-established. Against this background on burstiness as the indicator of the service process, burstiness is also defined as a factor that influences the service process. However, burstiness as a factor in the service process has not attracted a lot of research attention. The aim of this paper is to analyse burstiness as a factor in the service process underpinning the elaboration of scenarios of the service process for the queue management purposes. The present work mostly employs theoretical methods: scientific literature analysis, synthesis, modelling, comparison, and systematization. The theoretical research results in the outline of the conceptual framework for exploring the impact of burstiness on the service process. The key concepts have been identified, namely binary customer behaviour, buyers’ burstiness, bottlenecks’ emergence at the server, and queue management. The logical chain of the development has been emphasized: binary customer behaviour → buyers’ burstiness → bottlenecks’ emergence at the check-out station or cash register (server) → queue management. The presented logical chain allows finding out that buyers’ burstiness leads to the queue appearance in the service process. In turn, queue appearance requires queue management measures. Hence, buyers’ burstiness influences on the decisions in regard to queue management within the service process. Further on, two functions of buyers’ burstiness are defined: the indicators of the service process, and the factor that influences the service process. This bi-modal role of buyers’ burstiness in the service process highlights the complex nature of the queue management. Five scenarios of the service process will allow using a combination of queue management measures in each scenario or even between scenarios. The findings of the comparative study propose the structure of the service process as the unity of the waiting in the queue to the cash register and the payment processing at the cash register, i.e. scanning of the goods and the payment. The present research has some limitations. Further research tends to validate the model of five scenarios of the service process for the queue management purposes. Comparative studies on buyers’ burstiness in the service process will be continued, too.

It is shown that a gold-plated device mounted on a tenor saxophone, forming a small bridge between the mouthpiece and the S-bow, can change two characteristics of the radiated sound: (1) the radiated acoustic energy of the harmonics with emission maxima around 1500–3000 Hz, which is slightly reduced for tones played in the lower register of the saxophone, (2) the frequency jitter of all tones in the regular and upper register of the saxophone show a two-fold increase. Through simulated phase-shifted superimpositions of the recorded waves, it is shown that the cancellation of acoustic energy due to antiphase superimposition is significantly reduced in recordings with the bridge. Simulations with artificially generated acoustic waves confirm that acoustic waves with a certain systematic jitter show less cancelling of the acoustic energy under a phase-shifted superimposition, compared to acoustic waves with no frequency jitter, thus, being beneficial for live performances in small halls with minimal acoustic optimization. The data further indicate that the occasionally hearable “rumble” of a wind instrument orchestra with instruments showing slight differences in the frequency of the harmonics might be reduced (or avoided), if the radiated acoustic waves have a systematic jitter of a certain magnitude.

BackgroundClozapine is associated with increased risk of myocarditis. However, many common side-effects of clozapine overlap with the clinical manifestations of myocarditis. As a result, there is uncertainty about which signs, symptoms and investigations are important in distinguishing myocarditis from benign adverse effects of clozapine. Clarity on this issue is important, since missing a diagnosis of myocarditis or discontinuing clozapine unnecessarily may both have devastating consequences.AimsTo examine the clinical characteristics of clozapine-induced myocarditis and to identify which signs and symptoms distinguish true myocarditis from other clozapine adverse effects.MethodA retrospective analysis of the record database for 247 621 patients was performed. A natural language processing algorithm identified the instances of patients in which myocarditis was suspected. The anonymised case notes for the patients of each suspected instance were then manually examined, and those whose instances were ambiguous were referred for an independent assessment by up to three cardiologists. Patients with suspected instances were classified as having confirmed myocarditis, myocarditis ruled out or undetermined.ResultsOf 254 instances in 228 patients with suspected myocarditis, 11.4% (n = 29 instances) were confirmed as probable myocarditis. Troponin and C-reactive protein (CRP) had excellent diagnostic value (area under the curve 0.975 and 0.896, respectively), whereas tachycardia was of little diagnostic value. All confirmed instances occurred within 42 days of clozapine initiation.ConclusionsSuspicion of myocarditis can lead to unnecessary discontinuation of clozapine. The ‘critical period’ for myocarditis emergence is the first 6 weeks, and clinical signs including tachycardia are of low specificity. Elevated CRP and troponin are the best markers for the need for further evaluation.

The Italian National Statistical Institute (Istat) is currently engaged in a modernization programme that foresees a significant revision of the methods traditionally used for the production of official statistics. The main concept behind this transformation is the use of the Integrated System Statistical Registers, created by a massive integration of administrative archives and survey data. In this article, we focus on how to measure the accuracy of register estimates of a population total from measurements calculated at the unit level. We propose the global mean squared error (GMSE) as a statistical quantity suitable for measuring accuracy in the context of the production of official statistics. It can be defined to explicitly consider the main sources of uncertainty that may affect registers. The article suggests a feasible calculation strategy for the GMSE that allows National Statistical Institutes to build algorithms that can promptly be applied for each user request, thus improving the relevance, transparency and confidence of official statistics. Through a simulation study, we verified the efficacy of the proposed strategy.

The article describes the impact of the introduction of digital technologies on changes in the training of teaching staff, as well as the ability to manage the professional development trajectory of teaching staff through obtaining operational data on their competence profile using the software product 1C:Register of personnel. The basic requirements for the functionality and capabilities of automated information systems, with the help of which human resources management should be carried out, are analyzed and systematized. The results of using the software product, including the example of the implemented project in the executive authorities, in the framework of which the curator of the project was the 1С company, and the developer of the project was the Omega company, are given. The practical results of the implementation of the software product are reflected, related to the objectivity and reliability of data on the staff, with data on the amount of remuneration of employees of government bodies, sectoral departments and their subordinate institutions. The features of the functioning of information tools presented in the article allow you to manage access to the personnel management system, increase the productivity of personnel services and reduce the costs of organizing their work. It also becomes possible to manage the talent pool based on objective data on the development of competencies and updating the professional development trajectory of employees.