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Your search keyword '"Pingitore R"' showing total 185 results
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185 results on '"Pingitore R"'

1. Active learning groupwork based online tutorials

Author

Banks, J, Fijn, P, Maillardet, R, Morphett, A, Pingitore, R, Santin Garcia, A, Tran, T, Banks, J, Fijn, P, Maillardet, R, Morphett, A, Pingitore, R, Santin Garcia, A, and Tran, T

Abstract

Pre-COVID, we used ‘whiteboard tutorials’ in most of our large undergraduate mathematics and statistics subjects. Whiteboard tutorials take place in a classroom with whiteboards (or blackboards) around all the walls, and students work together in small groups on mathematical tasks at the boards. The classes are a form of active learning, helping students to develop skills such as group work and communication, and provide a valuable social element to students’ University experience. In this paper, we describe a model for online ‘whiteboard’ tutorials which preserves many of the strengths of the pre-COVID whiteboard tutorial model in an entirely online environment. We discuss some challenges with the model and possible mitigations.

Published
2021

5. Calcium Antagonists for Treatment of Diabetes-Associated Hypertension

Author

Riesen W, Pingitore R, Heinen G, Zanetti-Elshater F, and Beretta-Piccoli C

Subjects
medicine.medical_specialty, Mean arterial pressure, business.industry, Insulin, medicine.medical_treatment, Renal function, Essential hypertension, medicine.disease, Excretion, Endocrinology, Blood pressure, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Amlodipine, business, medicine.drug
Abstract

In hypertensive diabetics a strict blood pressure control may decrease the incidence of cardiovascular and diabetic complications. Long-term experience with the use of calcium antagonists is still limited. The metabolic and renal effects of long-term (8 months) therapy with amlodipine, 5 to 10 mg daily, were studied in 15 hypertensive patients with uncomplicated diabetes mellitus as compared with 15 patients with essential hypertension. After a 4 week placebo phase, the diabetics and essential hypertensive patients did not differ in mean blood pressure (156/93 +/- 16/7 v 150/95 +/- 9/5 mm Hg), body weight, creatinine clearance, microalbumin excretion, and C-peptide and lipid levels, while serum fructosamine was higher in the diabetics. In both groups, amlodipine caused a significant and long-lasting decrease of arterial pressure (8%), but did not modify creatinine clearance, microalbumin excretion, and serum lipid levels. In diabetics indices of diabetic control and the insulin and glucose response to an oral glucose tolerance test were unchanged, whereas in essential hypertension the insulin response to a glucose load was decreased (P = .033). Amlodipine exerts a comparable and long-lasting antihypertensive effect in hypertensive diabetics and patients with essential hypertension. Despite the significant decrease in arterial pressure, there was no change in urinary microalbumin excretion. Lipid metabolism, quality of diabetic control, and the insulin response to a glucose load were not affected unfavorably.

Published
1994

9. Oral Pathology - Third Edition

Author

Artese, L, Camilot, D, Colafranceschi, M, Foschini, Mp, Giardina, E, Leocata, Pietro, Maiorano, E, Maresi, E, Melato, M, Nardi, F, Navone, R, Pich, A, Pingitore, R, Rizzardi, C, Schneider, M, Sidoni, A, Stefani, M, and Tanda, F.

Published
2005

17. NEOANGIOGENESI IN ADENOCARCINOMI DEL COLON

Author

PINUCCIA FAVIANA, Laura Boldrini, Camacci, T., Gisfredi, S., Di Quirico, D., ROBERTO SPISNI, Raffaelli, M., paolo miccoli, Pingitore, R., and Gabriella Fontanini

Published
2001

21. Virtual endoscopy of the middle and inner ear with spiral computed tomography

Author

Emanuele Neri, Caramella, D., Battolla, L., Cosottini, M., Scasso, C. A., Bruschini, P., Pingitore, R., and Bartolozzi, C.

Subjects
User-Computer Interface, Culture Techniques, Ear, Inner, Therapy, Computer-Assisted, Ear, Middle, Humans, Endoscopy, Otologic Surgical Procedures, Tomography, X-Ray Computed, Mastoid
Abstract

To evaluate the inner anatomy of the auditory apparatus by means of virtual endoscopy of spiral computed tomography (CT) data sets.Virtual endoscopy permits simulation of the fiberoptic endoscopy perspective by processing CT or magnetic resonance images.Seven formalin-fixed specimens of human mastoid were scanned with spiral CT with the following protocol: beam collimation 1 mm, pitch ratio 1, reconstruction spacing 0.2 to 0.5 mm, field of view 90 mm. For the generation of endoscopic views of the auditory spaces, the axial images were processed with Navigator software 2.0 running on UltraSparc I workstation.Virtual endoscopy allowed the demonstration of the external auditory canal, the head and handle of the malleus, the stapes and incudostapedial articulation, the corpus, the long process of the incus with its lenticular process and the short limb, the malleoincudal articulation, the rounded promontory, the round and oval windows, and Prussak's space. From inside the basal turn of the cochlea, virtual endoscopy showed the orifices of the fenestrae cochlea and vestibuli, the origin of the lateral and the anterior semicircular canals, and the basal turn of cochlea. The optimal perspectives that allowed demonstration of the anatomical details of the middle and inner ear are described.Virtual endoscopy allows the generation of inner views of the auditory spaces. This new method of image processing can be proposed as an integrative tool of spiral CT imaging.

Published
2000

48. p53 expression in non small cell lung cancer: clinical and biological correlations

Author

Gabriella Fontanini, Bigini D, Vignati S, Macchiarini P, Pepe S, Ca, Angeletti, Pingitore R, and Squartini F

Subjects
Cell Nucleus, Lung Neoplasms, Ploidies, Nuclear Proteins, Middle Aged, Flow Cytometry, Genes, p53, Neoplasm Proteins, Ki-67 Antigen, Antigens, Neoplasm, Carcinoma, Non-Small-Cell Lung, Proliferating Cell Nuclear Antigen, Mutation, Humans, Tumor Suppressor Protein p53
Abstract

p53 is a tumor suppressor gene, located in the short arm of chromosome 17, which encodes for a nuclear protein involved in the control of cellular growth. Mutations in p53 gene are the most common genetic alterations in a several human cancers, including Non Small Cell Lung Cancer (NSCLC). However, up to now, the role of p53 in the tumour's behaviour and its progression has not been completely clear. We performed immunohistochemical staining for mutated p53 using two monoclonal antibodies, PAb1801 and PAb240, in fresh tumour specimens from 103 consecutive patients who underwent surgery for resectable NSCLC. PAb1801 detects both the normal and mutant form of p53, while PAb240 is specific only for the mutant form and recognizes a denaturation-resistant epitope located between aminoacids 156-335. Both antibodies showed a mainly nuclear staining in neoplastic cells but not in surrounding uninvolved lung tissues. 68 out of 100 (68%) and 37 out of 103 (35.9%) of the cases were positive with PAb1801 and with PAb240, respectively. Tumours from patients with hilar-mediastinal lymph node involvement showed a higher p53 expression, detected by PAb1801, than those without nodal metastases (p = 0.04). Moreover, tumours expressing more than 60% of positive cells with both antibodies showed a significant increase of nodal involvement (p = 0.1; p = 0.03). Furthermore, p53 expression was significantly related to post-surgical stage (p Tumor Stage) (p = 0.04). In addition, we did not find any correlation between p53 expression and proliferating activity evaluated by PCNA, Ki-67 and DNA flow cytometric cell cycle. In conclusion, the evaluation of p53 oncogene expression may identify individuals whose resectable NSCLCs have a more aggressive tumour behaviour.

Published
1993

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