33 results on '"Neofytou, Marios"'
Search Results
2. The role of tele-ophthalmology in diabetic retinopathy screening
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Kalogeropoulos, Dimitrios, Kalogeropoulos, Chris, Stefaniotou, Maria, and Neofytou, Marios
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- 2020
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3. The Role of Hysteroembryoscopy in the Management of Spontaneous and Repeated Pregnancy Loss
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Tanos, Vasilios, Georgiou, Demetra, Neofytou, Marios, Meridis, Eleftherios, Paschopoulos, Minas, Tinelli, Andrea, editor, Alonso Pacheco, Luis, editor, and Haimovich, Sergio, editor
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- 2018
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4. Enhancing Healthcare Accessibility: A Teleconsultation Mobile Application for Patient-Centric Care in Cyprus
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Canciu, Ionut Cristian, primary, Pattichis, Constantinos S., additional, Christodoulou, Marios, additional, Agroti, Louiza, additional, Papaioannou, Maria, additional, Neocleous, Andreas, additional, Savva, Panayiotis, additional, Yiasemi, Constantinos, additional, Neofytou, Marios, additional, Panayides, Andreas, additional, Antoniou, Zinonas, additional, and Constantinou, Ioannis, additional
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- 2023
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5. Haemostasis in Minimal Invasive Gynaecological Surgery Energies: Technical Aspects, Safety and Efficacy
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Tanos, Vasilios, Neofytou, Marios, Pattichis, Constantinos, Magjarevic, Ratko, Editor-in-chief, Ładyżyński, Piotr, Series editor, Ibrahim, Fatimah, Series editor, Lacković, Igor, Series editor, Rock, Emilio Sacristan, Series editor, Kyriacou, Efthyvoulos, editor, Christofides, Stelios, editor, and Pattichis, Constantinos S., editor
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- 2016
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6. The International Patient Summary: Proposal for a National Implementation for Cyprus
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Neocleous, Andreas, primary, Papaioannou, Maria, additional, Savva, Panayiotis, additional, Miguel, Francisco, additional, Panayides, Andreas, additional, Antoniou, Zinonas, additional, Neofytou, Marios, additional, Schiza, Eirini C., additional, Neokleous, Kleanthis, additional, Constantinou, Ioannis, additional, Panos, George, additional, Schizas, Christos N., additional, and Pattichis, Constantinos S., additional
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- 2022
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7. Computer-Aided Diagnosis by Tissue Image Analysis as an Optical Biopsy in Hysteroscopy
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Tanos, Vasilios, primary, Neofytou, Marios, additional, Tanos, Panayiotis, additional, Pattichis, Constantinos S., additional, and Pattichis, Marios S., additional
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- 2022
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8. Classification and Data Mining for Hysteroscopy Imaging in Gynaecology
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Neofytou, Marios, Loizou, A., Tanos, V., Pattichis, M. S., Pattichis, C. S., Magjarevic, R., editor, Nagel, J. H., editor, Vander Sloten, Jos, editor, Verdonck, Pascal, editor, Nyssen, Marc, editor, and Haueisen, Jens, editor
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- 2009
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9. The Role of Hysteroembryoscopy in the Management of Spontaneous and Repeated Pregnancy Loss
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Tanos, Vasilios, primary, Georgiou, Demetra, additional, Neofytou, Marios, additional, Meridis, Eleftherios, additional, and Paschopoulos, Minas, additional
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- 2017
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10. Systems and methods for processing errors in digital beamforming receivers
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Athanasiadis, Pavlos, Doris, Kostas, Neofytou, Marios, Radulov, Georgi I., Athanasiadis, Pavlos, Doris, Kostas, Neofytou, Marios, and Radulov, Georgi I.
- Abstract
An apparatus, such as a radar system that conducts beamforming operations, includes a plurality of analog-to-digital-converters (ADCs) and an error correction system coupled to the ADCs. Based upon an assessment of a plurality of errors associated with the ADCs by the error correction system, the error correction system programs sampling operations for the ADCs. The error correction system includes an error correction unit that identifies the plurality of errors associated with a plurality of sub-ADCs of the ADCs, a selection unit coupled to the error correction unit that sorts the errors associated with the plurality of sub-ADCs, and a programming unit coupled to the selection unit that reconfigures the sorted errors to generate a sequence of sampling operations for the plurality of sub-ADCs. Using, for example, a barrel shifter function, the sorted errors are reconfigured by the programming unit such that a summation of elements in each column in a matrix in which the sorted errors are stored are within a predefined value.
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- 2022
11. Systems and methods for calibration of in-phase/quadrature (I/Q) modulators
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Neofytou, Marios, Doris, Kostas, Ganzerli, Marcello, Radulov, Georgi I., Athanasiadis, Pavlos, Neofytou, Marios, Doris, Kostas, Ganzerli, Marcello, Radulov, Georgi I., and Athanasiadis, Pavlos
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A wireless transceiver system includes a transmitter and a receiver. The transmitter includes a digital processor and a self-correction modulator coupled to the digital processor, wherein based upon a calibration correction assessment of an in-phase (I) signal and a quadrature (Q) signal received from the digital processor, the self-correction modulator generates a calibrated modulated signal. The self-correction modulator includes a core modulator and a calibration correction unit. The calibration correction unit is configured to correct an output of the core modulator based upon the calibration correction assessment. The calibration correction unit includes a calibration processing unit and a calibration modulator, wherein the calibration processing unit provides correction quantities that are used to program the calibration modulator to provide the self-corrected modulated signal.
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- 2022
12. eHealth4U: A DEMO of a Prototype National Electronic Health Record for Cyprus.
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NEOCLEOUS, Andreas, PAPAIOANNOU, Maria, SAVVA, Panayiotis, MIGUEL, Francisco, YIASEMI, Constantinos, PANAYIDES, Andreas, ANTONIOU, Zinonas, NEOFYTOU, Marios, MICHAEL, Christos, MELIOS, Panayiotis, CONSTANTINOU, Ioannis, CÂNCIU, Ionuț–Cristian, ADAMIDES, Giorgos, CHRISTODOULOU, Marios, and PATTICHIS, Constantinos
- Abstract
In this paper we present a demonstration of a prototype national Electronic Health Record platform for Cyprus. This prototype is developed using the HL7 FHIR interoperability standard in combination with terminologies widely adopted by the clinical community such as the SNOMED CT and the LOINC. The system is organized in such a way to be user-friendly for its users, being the doctors and the citizens. The health-related data of this EHR are separated into three main sections, being the “Medical History”, the “Clinical Examination” and the “Laboratory results”. Business requirements include the Patient Summary as defined by the guidelines of the eHealth network and the International Patient Summary which are used as the base for all the sections of our EHR, together with additional medical information and functionality such as the organization of medical teams or the history of medical visits and episodes of care. From the doctor’s point of view, one can search for patients who have granted the doctor with a consent and read or add/edit their EHR data by initiating a new visit as defined in the Cyprus National Law for eHealth. At the same time, doctors can organize their medical teams by managing the locations of each team and the members that belong to each team. [ABSTRACT FROM AUTHOR]
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- 2023
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13. MYeHealthAppCY: A Healthcare Mobile Application in Cyprus.
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AGROTI, Louiza, CANCIU, Ionut-Cristian, CHRISTODOULOU, Marios, PAPAIOANNOU, Maria, NEOCLEOUS, Andreas, SAVVA, Panayiotis, YIASEMI, Constantinos, SOLOMOU, Theodoros, PANAYIDES, Andreas, ANTONIOU, Zinonas, NEOFYTOU, Marios, CONSTANTINOU, Ioannis, and PATTICHIS, Constantinos S.
- Abstract
This paper presents MYeHealthAppCY, an mHealth solution designed to provide patients and healthcare providers in Cyprus with access to medical data. The application includes features such as an at-a-glance view of patient summary, comprehensive prescription management, teleconsultation, and the ability to store and access European Digital COVID Certificates (EUDCC). The application is an integral part of the eHealth4U platform targeting to implement a prototype EHR platform for national use. The application developed is based on FHIR and follows a strict adherence to widely used coding standards. The application was evaluated receiving satisfactory scores; however, significant work is still needed to deploy the application in production. [ABSTRACT FROM AUTHOR]
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- 2023
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14. Haemostasis in Minimal Invasive Gynaecological Surgery Energies: Technical Aspects, Safety and Efficacy
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Tanos, Vasilios, primary, Neofytou, Marios, additional, and Pattichis, Constantinos, additional
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- 2016
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15. Is Computer-Assisted Tissue Image Analysis the Future in Minimally Invasive Surgery? A Review on the Current Status of Its Applications
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Tanos, Vasilios, primary, Neofytou, Marios, additional, Soliman, Ahmed Samy Abdulhady, additional, Tanos, Panayiotis, additional, and Pattichis, Constantinos S., additional
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- 2021
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16. Quantitative Analysis of Hysteroscopy Imaging in Gynecological Cancer
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Neofytou, Marios, primary, Pattichis, Constantinos, additional, Tanos, Vasilios, additional, Pattichis, Marios, additional, and Kyriacou, Eftyvoulos, additional
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- 2009
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17. A novel analysis of the beam squinting in wideband phased array digital I/Q transmitters
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Manev, Veselin, primary, Neofytou, Marios, additional, Radulov, Georgi, additional, and Doris, Kostas, additional
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- 2020
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18. Computer-Aided Diagnosis in Hysteroscopic Imaging
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Neofytou, Marios S., Tanos, Vasilios, Constantinou, Ioannis P., Kyriacou, Efthyvoulos C., Pattichis, Marios S., Pattichis, Constantinos S., Pattichis, Constantinos S. [0000-0003-1271-8151], Pattichis, Marios S. [0000-0002-1574-1827], and Kyriacou, Efthyvoulos C. [0000-0002-4589-519X]
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Computer science ,Computer-aided hysteroscopy ,Diseases ,CAD ,HSL and HSV ,User-Computer Interface ,Probabilistic neural network ,Endometrial cancer ,Health Information Management ,Image texture ,middle aged ,Computer vision ,Texture features ,receiver operating characteristic ,Classification (of information) ,Classification rates ,Textures ,Middle Aged ,Classification ,Computer Science Applications ,Computer aided diagnosis ,female ,Female ,Neural networks ,Biotechnology ,Feature extraction ,computer interface ,Hysteroscopy ,Computer-aided diagnostic (CAD) ,Probabilistic neural networks ,Image Interpretation, Computer-Assisted ,Humans ,human ,procedures ,Electrical and Electronic Engineering ,Gray level differences ,Support vector machines ,uterus ,business.industry ,Uterus ,Endoscopy ,computer assisted diagnosis ,Pattern recognition ,Endometrial Neoplasms ,Support vector machine ,Support vector machine (SVMs) ,ROC Curve ,Computer-aided diagnosis ,Computer aided diagnostics ,RGB color model ,pathology ,Artificial intelligence ,business - Abstract
The paper presents the development of a computeraided diagnostic (CAD) system for the early detection of endometrial cancer. The proposed CAD system supports reproducibility through texture feature standardization, standardized multifeature selection, and provides physicians with comparative distributions of the extracted texture features. The CAD system was validated using 516 regions of interest (ROIs) extracted from 52 subjects. The ROIs were equally distributed among normal and abnormal cases. To support reproducibility, the RGB images were first gamma corrected and then converted into HSV and YCrCb. From each channel of the gamma-corrected YCrCb, HSV, and RGB color systems, we extracted the following texture features: 1) statistical features (SFs), 2) spatial gray-level dependence matrices (SGLDM), and 3) gray-level difference statistics (GLDS). The texture features were then used as inputs with support vector machines (SVMs) and the probabilistic neural network (PNN) classifiers. After accounting for multiple comparisons, texture features extracted from abnormal ROIs were found to be significantly different than texture features extracted from normal ROIs. Compared to texture features extracted from normal ROIs, abnormal ROIs were characterized by lower image intensity, while variance, entropy, and contrast gave higher values. In terms of ROI classification, the best results were achieved by using SF and GLDS features with an SVM classifier. For this combination, the proposed CAD system achieved an 81% correct classification rate. 2168-2194 © 2014 IEEE. 19 3 1129 1136 Cited By :2
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- 2015
19. A standardised protocol for texture feature analysis of endoscopic images in gynaecological cancer
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Pattichis Marios S, Pattichis Constantinos S, Tanos Vasilis, Neofytou Marios S, Kyriacou Efthyvoulos C, and Koutsouris Dimitris D
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Medical technology ,R855-855.5 - Abstract
Abstract Background In the development of tissue classification methods, classifiers rely on significant differences between texture features extracted from normal and abnormal regions. Yet, significant differences can arise due to variations in the image acquisition method. For endoscopic imaging of the endometrium, we propose a standardized image acquisition protocol to eliminate significant statistical differences due to variations in: (i) the distance from the tissue (panoramic vs close up), (ii) difference in viewing angles and (iii) color correction. Methods We investigate texture feature variability for a variety of targets encountered in clinical endoscopy. All images were captured at clinically optimum illumination and focus using 720 × 576 pixels and 24 bits color for: (i) a variety of testing targets from a color palette with a known color distribution, (ii) different viewing angles, (iv) two different distances from a calf endometrial and from a chicken cavity. Also, human images from the endometrium were captured and analysed. For texture feature analysis, three different sets were considered: (i) Statistical Features (SF), (ii) Spatial Gray Level Dependence Matrices (SGLDM), and (iii) Gray Level Difference Statistics (GLDS). All images were gamma corrected and the extracted texture feature values were compared against the texture feature values extracted from the uncorrected images. Statistical tests were applied to compare images from different viewing conditions so as to determine any significant differences. Results For the proposed acquisition procedure, results indicate that there is no significant difference in texture features between the panoramic and close up views and between angles. For a calibrated target image, gamma correction provided an acquired image that was a significantly better approximation to the original target image. In turn, this implies that the texture features extracted from the corrected images provided for better approximations to the original images. Within the proposed protocol, for human ROIs, we have found that there is a large number of texture features that showed significant differences between normal and abnormal endometrium. Conclusion This study provides a standardized protocol for avoiding any significant texture feature differences that may arise due to variability in the acquisition procedure or the lack of color correction. After applying the protocol, we have found that significant differences in texture features will only be due to the fact that the features were extracted from different types of tissue (normal vs abnormal).
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- 2007
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20. Electronic Health Record Application Support Service Enablers
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Neofytou, Marios S., Neokleous, Kleanthis C., Aristodemou, Andrie, Constantinou, Ioannis P., Antoniou, Zinonas C., Schiza, Eirini C., Pattichis, Constantinos S., Schizas, Christos N., Schizas, Christos N. [0000-0001-6548-4980], Pattichis, Constantinos S. [0000-0003-1271-8151], Schiza, Eirini C. [0000-0002-3593-6605], and Antoniou, Zinonas C. [0000-0002-5148-5197]
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Engineering ,Service (systems architecture) ,Internet ,Knowledge management ,business.industry ,Interoperability ,Context (language use) ,computer.file_format ,Clinical Document Architecture ,Telemedicine ,World Wide Web ,Radiology Information Systems ,Software deployment ,Health care ,eHealth ,Electronic Health Records ,The Internet ,business ,computer ,Software - Abstract
There is a huge need for open source software solutions in the healthcare domain, given the flexibility, interoperability and resource savings characteristics they offer. In this context, this paper presents the development of three open source libraries - Specific Enablers (SEs) for eHealth applications that were developed under the European project titled 'Future Internet Social and Technological Alignment Research' (FI-STAR) funded under the 'Future Internet Public Private Partnership' (FI-PPP) program. The three SEs developed under the Electronic Health Record Application Support Service Enablers (EHR-EN) correspond to: a) an Electronic Health Record enabler (EHR SE), b) a patient summary enabler based on the EU project 'European patient Summary Open Source services' (epSOS SE) supporting patient mobility and the offering of interoperable services, and c) a Picture Archiving and Communications System (PACS) enabler (PACS SE) based on the dcm4che open source system for the support of medical imaging functionality. The EHR SE follows the HL7 Clinical Document Architecture (CDA) V2.0 and supports the Integrating the Healthcare Enterprise (IHE) profiles (recently awarded in Connectathon 2015). These three FI-STAR platform enablers are designed to facilitate the deployment of innovative applications and value added services in the health care sector. They can be downloaded from the FI-STAR cataloque website. Work in progress focuses in the validation and evaluation scenarios for the proving and demonstration of the usability, applicability and adaptability of the proposed enablers. © 2015 IEEE. 2015-November 1401 1404 Sponsors: Conference code: 116805 Cited By :1
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- 2015
21. A comparison of color correction algorithms for endoscopic cameras
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Constantinou, Ioannis P., Neofytou, Marios S., Tanos, Vasilios, Pattichis, Marios S., Christodoulou, Chris C., Pattichis, Constantinos S., Pattichis, Constantinos S. [0000-0003-1271-8151], Christodoulou, Chris C. [0000-0001-9398-5256], and Pattichis, Marios S. [0000-0002-1574-1827]
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Polynomial ,Mean squared error ,Computer science ,business.industry ,Color correction ,ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION ,Color tissue ,Tissue characterization ,Correction algorithm ,Computer-aided diagnosis ,Gamma correction ,Computer vision ,Artificial intelligence ,business ,Algorithm - Abstract
Quantitative color tissue analysis in endoscopy examinations requires color standardization procedures to be applied, so as to enable compatibility among computer aided diagnosis application from different endoscopy labs. The objective of this study was to examine the usefulness of different color correction algorithms (thus facilitating color standardization), evaluated on four different endoscopy cameras. The following five color correction algorithms were investigated: two gamma correction based algorithms (the classical and a modified one), and three (2nd, 3rd, and 4th order) polynomial based correction algorithms. The above algorithms were applied to four different endoscopy cameras: (a) Circon, (b) Karl-Stortz, (c) Olympus, and (d) Snowden-Pencer. The color correction algorithms and the endoscopic cameras evaluation, was carried out using the testing color palette (24 colors of known digital values) provided by the Edmund Industrial Optics Company. In summary, we have that: (a) the modified gamma correction algorithm gave significantly smaller mean square error compared to the other four algorithms, and (b) the smallest mean square error was obtained for the Circon camera. Future work will focus on evaluating the proposed color correction algorithm in different endoscopy clinics and compare their tissue characterization results. © 2013 IEEE. Sponsors: Institute of Electrical and Electronic Engineers (IEEE) Artificial Intelligence Foundation (BAIF) Conference code: 102484
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- 2013
22. A Web services-based exergaming platform for senior citizens: The long lasting memories project approach to e-health care
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Bamidis, Panagiotis D., Konstantinidis, E. I., Billis, A., Frantzidis, C., Tsolaki, M., Hlauschek, W., Kyriacou, Efthyvoulos C., Neofytou, Marios S., Pattichis, Constantinos S., Pattichis, Constantinos S. [0000-0003-1271-8151], and Kyriacou, Efthyvoulos C. [0000-0002-4589-519X]
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User interfaces ,Engineering ,Telemedicine ,Training schemes ,computer.software_genre ,Rendering (computer graphics) ,memory ,Memory ,Health care ,Humans ,human ,Innovation ,Training sessions ,Web services ,Aged ,E-health services ,Internet ,Multimedia ,business.industry ,article ,Web service architecture ,Modular design ,Senior citizens ,E-health care ,Active ageing ,aged ,Physical training ,Project approach ,Long lasting ,The Internet ,telemedicine ,User interface ,Web service ,business ,computer - Abstract
This piece of research describes an innovative e-health service that supports the cognitive and physical training of senior citizens and promotes their active ageing. The approach is adopted by the Long Lasting Memories (LLM) project, elements of which are discussed herein in the light of the functionalities provided to the users and the therapists. The aim of this work is to describe those technical elements that demonstrate the unique and integrative character of the LLM service, which is based on a modular Web service architecture, rendering the system available in different settings like the homes of seniors. The underlying database as well as the remote user interface empower therapists to set personalized training schemes, to view the progress of training sessions, as well as, adding new games and exercises into the system, thereby increasing the services sustainability and marketability. © 2011 IEEE. 2505 2509 Conference code: 87843 Cited By :20
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- 2011
23. A simplified 2D real time navigation system for hysteroscopy imaging
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Herakleous, I., Constantinos, I. P., Michael, E., Neofytou, Marios S., Pattichis, Constantinos S., Tanos, Vasilios, and Pattichis, Constantinos S. [0000-0003-1271-8151]
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Position sensors ,Quantitative image analysis ,Computer science ,Diseases ,Hysteroscopy ,Navigation systems ,Pathophysiology ,Endometrial Cancer ,Measurement errors ,medicine ,Computer vision ,Real-time navigation ,Tissue ,medicine.diagnostic_test ,business.industry ,Hysteroscopy Imaging ,Navigation system ,Real time systems ,Endoscopy ,Navigation ,Key (cryptography) ,Artificial intelligence ,business ,Position sensor ,Real time navigation - Abstract
In this paper, a simplified 2D navigation system for hysteroscopy imaging was introduced. This system was evaluated in virtual endometrium models, and the position sensor measurement errors were very small and acceptable by the physician. The 2D navigation system, combined with quantitative image analysis will help the physician in gaining a better understanding of the pathophysiology of the tissue under investigation. Key words: Endometrial Cancer, Navigation, Hysteroscopy Imaging. © 2011 ACM. 578 347 352 Sponsors: Technical University of Sofia Inst. Inf. Commun. Technol. - BAS (IOIACTBB) Technical University of Varna (TECHUVB) Fed. Sci. Eng. Unions - Bulgaria (FOSEUB) Lifelong Learning Programme - ETN TRICE Conference code: 86480 Cited By :1
- Published
- 2011
24. Color multiscale texture classification of hysteroscopy images of the endometrium
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Neofytou, Marios S., Tanos, Vasilios, Pattichis, Marios S., Kyriacou, Efthyvoulos C., Pattichis, Constantinos S., Schizas, Christos N., Schizas, Christos N. [0000-0001-6548-4980], Pattichis, Constantinos S. [0000-0003-1271-8151], Pattichis, Marios S. [0000-0002-1574-1827], and Kyriacou, Efthyvoulos C. [0000-0002-4589-519X]
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Chromium ,Svm models ,System-based ,Security of data ,Color ,Gray levels ,Statistical features ,Probabilistic neural networks ,Endometrium ,Different scale ,Feature sets ,Texture features ,Multi-scale ,Neural network classifiers ,Gynaecological cancer ,Support vector machines ,Computer aided design ,Computer aided analysis ,Early detections ,Endoscopy ,Textures ,Color systems ,Statistical learning ,Regions of interests ,Texture analysis ,Cad systems ,Texture classifications ,Computer-aided diagnostics ,RGB images ,Color multiscale analysis ,Hysteroscopy imaging ,Diagnostic performance ,Neural networks ,Multiscale texture analysis - Abstract
The objective of this study was to investigate the diagnostic performance of a Computer Aided Diagnostic (CAD) system based on color multiscale texture analysis for the classification of hysteroscopy images of the endometrium, in support of the early detection of gynaecological cancer. A total of 416 Regions of Interest (ROIs) of the endometrium were extracted (208 normal and 208 abnormal) from 45 subjects. RGB images were gamma corrected and were converted to the YCrCb color system. The following texture features were extracted from the Y, Cr and Cb channels: (i) Statistical Features (SF), (ii) Spatial Gray Level Dependence Matrices (SGLDM), and (iii) Gray Level Difference Statistics (GLDS). The Probabilistic Neural Network (PNN), statistical learning and the Support Vector Machine (SVM) neural network classifiers were also applied for the investigation of classifying normal and abnormal ROIs in different scales. Results showed that the highest percentage of correct classification (%CC) score was 79% and was achieved for the SVM models trained with the SF and GLDS features for the lxl scale. This %CC was higher by only 2% when compared with the CAD system developed, based on the SF and GLDS feature sets computed from the Y channel only. Further increase in scale from 2×2 to 9×9, dropped the %CC in the region of 60% for the SF, SGLDM, and GLDS, feature sets, and their combinations. Concluding, a CAD system based on texture analysis and SVM models can be used to classify normal and abnormal endometrium tissue in difficult cases of gynaecological cancer. The proposed system has to be investigated with more cases before it is applied in clinical practise. © 2008 IEEE. 1226 1229 Conference code: 75336 Cited By :1
- Published
- 2008
25. Color based texture--classification of hysteroscopy images of the endometrium
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Neofytou, Marios S., Tanos, Vasilios, Pattichis, Marios S., Pattichis, Constantinos S., Kyriacou, Efthyvoulos C., Pavlopoulos, Sotirios A., Pattichis, Constantinos S. [0000-0003-1271-8151], Pattichis, Marios S. [0000-0002-1574-1827], and Kyriacou, Efthyvoulos C. [0000-0002-4589-519X]
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Wilcoxon signed-rank test ,Image classification ,Feature extraction ,Color ,HSL and HSV ,Hysteroscopy ,Grayscale ,Sensitivity and Specificity ,Pattern Recognition, Automated ,Endometrium ,Image texture ,Artificial Intelligence ,Image Interpretation, Computer-Assisted ,Humans ,Computer vision ,Mathematics ,Gynaecological cancer ,Support vector machines ,Contextual image classification ,business.industry ,Reproducibility of Results ,Textures ,Pattern recognition ,Regions of Interest (ROI) ,Image Enhancement ,Statistical learning ,Endometrial Neoplasms ,Support vector machine ,Hysteroscopy images ,RGB color model ,Colorimetry ,Female ,Artificial intelligence ,business ,Neural networks ,Algorithms - Abstract
The objective of this study was to develop a CAD system for the classification of hysteroscopy images of the endometrium based on color texture analysis for the early detection of gynaecological cancer. A total of 416 Regions of Interest (ROIs) of the endometrium were extracted (208 normal and 208 abnormal) from 40 subjects. RGB images were gamma corrected and were converted to the HSV and YCrCb color systems. The following texture features were extracted for each channel of the RGB, HSV, and YCrCb systems: (1) Statistical Features, (ii) Spatial Gray Level Dependence Matrices and (iii) Gray Level Difference Statistics. The PNN statistical learning and SVM neural network classifiers were also investigated for classifying normal and abnormal ROIs. Results show that there is significant difference (using the Wilcoxon Rank Sum Test at a=0.05) between the texture features of normal and abnormal ROIs of the endometrium. Abnormal ROIs had higher gray scale median, variance, entropy and contrast and lower gray scale median and homogeneity values when compared to the normal ROIs. The highest percentage of correct classifications score was 79% and was achieved for the SVM models trained with the SF and GLDS features for differentiating between normal and abnormal ROIs. Concluding, a CAD system based on texture analysis and SVM models can be used to classify normal and abnormal endometrium tissue. Further work is needed to validate the system in more cases and organs. © 2007 IEEE. 864 867 Sponsors: ACIES, Research Promotion and Management Consulting EOARD, European Office of Aerospace R and D Grand Lyon NSF, National Science Foundation Philips Research Europe Philips Research North America Conference code: 70818 Cited By :6
- Published
- 2007
26. A standardised protocol for texture feature analysis of endoscopic images in gynaecological cancer
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Neofytou, Marios S., Tanos, Vasilios, Pattichis, Marios S., Pattichis, Constantinos S., Kyriacou, Efthyvoulos C., Koutsouris, Demetrios Dionysios, Pattichis, Constantinos S. [0000-0003-1271-8151], Pattichis, Marios S. [0000-0002-1574-1827], and Kyriacou, Efthyvoulos C. [0000-0002-4589-519X]
- Subjects
Statistical methods ,Computer science ,Tissue classification methods ,Gynaecological cancer ,Pattern Recognition, Automated ,Image analysis ,darkness ,image quality ,Computer vision ,animal ,statistical significance ,Microscopy, Video ,Radiological and Ultrasound Technology ,Color correction ,illumination ,article ,Approximation theory ,Discriminant Analysis ,standard ,artifact ,methodology ,Signal Processing, Computer-Assisted ,General Medicine ,Darkness ,Reference Standards ,Laboratory Techniques and Procedures ,endometrium tumor ,automated pattern recognition ,female ,lcsh:R855-855.5 ,Calibration ,microscopy ,Feature extraction ,Female ,gynecologic cancer ,image subtraction ,Artifacts ,Biomedical engineering ,lcsh:Medical technology ,chicken ,Biomedical Engineering ,Color ,Spatial Gray Level Dependence Matrices ,color discrimination ,Texture (music) ,Biomaterials ,statistical analysis ,process optimization ,diagnosis, measurement and analysis ,Image acquisition ,Humans ,Animals ,Radiology, Nuclear Medicine and imaging ,controlled study ,human ,image enhancement ,endoscopy ,Gray Level Difference Statistics ,Texture feature analysis ,Texture feature ,signal processing ,reproducibility ,Protocol (science) ,standardization ,algorithm ,Tissue ,business.industry ,Clinical Laboratory Techniques ,Research ,videorecording ,Reproducibility of Results ,Endoscopy ,Linear discriminant analysis ,Image Enhancement ,calibration ,discriminant analysis ,Endometrial Neoplasms ,color ,endometrium cancer ,cattle ,Subtraction Technique ,Classification methods ,Optical correlation ,Cattle ,pathology ,Artificial intelligence ,business ,clinical protocol ,Chickens - Abstract
Background: In the development of tissue classification methods, classifiers rely on significant differences between texture features extracted from normal and abnormal regions. Yet, significant differences can arise due to variations in the image acquisition method. For endoscopic imaging of the endometrium, we propose a standardized image acquisition protocol to eliminate significant statistical differences due to variations in: (i) the distance from the tissue (panoramic vs close up), (ii) difference in viewing angles and (iii) color correction. Methods: We investigate texture feature variability for a variety of targets encountered in clinical endoscopy. All images were captured at clinically optimum illumination and focus using 720 × 576 pixels and 24 bits color for: (i) a variety of testing targets from a color palette with a known color distribution, (ii) different viewing angles, (iv) two different distances from a calf endometrial and from a chicken cavity. Also, human images from the endometrium were captured and analysed. For texture feature analysis, three different sets were considered: (i) Statistical Features (SF), (ii) Spatial Gray Level Dependence Matrices (SGLDM), and (iii) Gray Level Difference Statistics (GLDS). All images were gamma corrected and the extracted texture feature values were compared against the texture feature values extracted from the uncorrected images. Statistical tests were applied to compare images from different viewing conditions so as to determine any significant differences. Results: For the proposed acquisition procedure, results indicate that there is no significant difference in texture features between the panoramic and close up views and between angles. For a calibrated target image, gamma correction provided an acquired image that was a significantly better approximation to the original target image. In turn, this implies that the texture features extracted from the corrected images provided for better approximations to the original images. Within the proposed protocol, for human ROIs, we have found that there is a large number of texture features that showed significant differences between normal and abnormal endometrium. Conclusion: This study provides a standardized protocol for avoiding any significant texture feature differences that may arise due to variability in the acquisition procedure or the lack of color correction. After applying the protocol, we have found that significant differences in texture features will only be due to the fact that the features were extracted from different types of tissue (normal vs abnormal). © 2007 Neofytou et al licensee BioMed Central Ltd. 6 Tradenames: IP4.1 RGB video camera, Circon Manufacturers: Circon Cited By :10
- Published
- 2007
27. Texture-based classification of hysteroscopy images of the endometrium
- Author
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Neofytou, Marios S., Pattichis, Marios S., Pattichis, Constantinos S., Tanos, Vasilios, Kyriacou, Efthyvoulos C., Koutsouris, Demetrios Dionysios, Pattichis, Constantinos S. [0000-0003-1271-8151], Pattichis, Marios S. [0000-0002-1574-1827], and Kyriacou, Efthyvoulos C. [0000-0002-4589-519X]
- Subjects
Statistical methods ,Computer science ,Feature extraction ,Biomedical Engineering ,Video Recording ,Hysteroscopy ,Endometrium ,Grayscale ,Image analysis ,histology ,Probabilistic neural network ,Image texture ,biomedical engineering ,Image Interpretation, Computer-Assisted ,medicine ,Humans ,Computer vision ,human ,Diagnosis, Computer-Assisted ,hysteroscopy ,Support vector machines ,Contextual image classification ,business.industry ,videorecording ,article ,Pattern recognition ,methodology ,computer assisted diagnosis ,Endometrial Neoplasms ,Support vector machine ,endometrium tumor ,medicine.anatomical_structure ,female ,Oncology ,Texture analysis ,Texture based classification ,statistics ,Gynecology ,Hysteroscopy images ,Female ,pathology ,Artificial intelligence ,business ,Neural networks - Abstract
The objective of this study was to classify hysteroscopy images of the endometrium based on texture analysis for the early detection of gynaecological cancer. A total of 418 Regions of Interest (ROIs) were extracted (209 normal and 209 abnormal) from 40 subjects. Images were gamma corrected and were converted to gray scale. The following texture features were extracted: (i) Statistical Features, (ii) Spatial Gray Level Dependence Matrices (SGLDM), and (iii) Gray level difference statistics (GLDS). The PNN and SVM neural network classifiers were also investigated for classifying normal and abnormal ROIs. Results show that there is significant difference (using Wilcoxon Rank Sum Test at a=0.05) between the texture features of normal and abnormal ROIs for both the gamma corrected and uncorrected images. Abnormal ROIs had lower gray scale median and homogeneity values, and higher entropy and contrast values when compared to the normal ROIs. The highest percentage of correct classifications score was 77% and was achieved for the SVM models trained with the SF and GLDS features. Concluding, texture features provide useful information differentiating between normal and abnormal ROIs of the endometrium. © 2006 IEEE. 3005 3008 Conference code: 69200 Cited By :6
- Published
- 2006
28. An adaptive multiscale AM-FM texture analysis system with application to hysteroscopy imaging
- Author
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Constantinou, Ioannis, primary, Pattichis, Marios, additional, Tanos, Vasilis, additional, Neofytou, Marios, additional, and Pattichis, Constantinos, additional
- Published
- 2012
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29. A simplified 2D real time navigation system for hysteroscopy imaging
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Herakleous, Ioanna, primary, Constantinos, Ioannis P., additional, Michael, Elena, additional, Neofytou, Marios S., additional, Pattichis, Constantinos S., additional, and Tanos, Vasillis, additional
- Published
- 2011
- Full Text
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30. A standardised protocol for texture feature analysis of endoscopic images in gynaecological cancer
- Author
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Neofytou, Marios S, primary, Tanos, Vasilis, additional, Pattichis, Marios S, additional, Pattichis, Constantinos S, additional, Kyriacou, Efthyvoulos C, additional, and Koutsouris, Dimitris D, additional
- Published
- 2007
- Full Text
- View/download PDF
31. A simplified 2D real time navigation system for hysteroscopy imaging.
- Author
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Herakleous, Ioanna, Constantinos, Ioannis P., Michael, Elena, Neofytou, Marios S., Pattichis, Constantinos S., and Tanos, Vasillis
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- 2011
- Full Text
- View/download PDF
32. A Prototype of the National EHR system for Cyprus .
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Papaioannou M, Neocleous A, Savva P, Miguel F, Panayides A, Antoniou Z, Neofytou M, Schiza EC, Neokleous K, Constantinou I, Panos G, Pattichis CS, and Schizas CN
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- Cyprus, Software, Electronic Health Records, Telemedicine
- Abstract
The aim of this paper is to present Cyprus' initiative for the design and the implementation of the prototype of the integrated electronic health record at a national level that will establish the foundations of the country's broader eHealth ecosystem. The latter, requires an interdisciplinary approach and scientific collaboration among various fields, including medicine, information and communication technologies, management, and finance, among others. The objective, is to design the system architecture, specify the requirements in terms of clinical content as well as the hardware infrastructure, but also implement European and national legislation with respect to privacy and security that govern sensitive medical data manipulation. The present study summarizes the outcomes of the 1
st phase of this initiative, which comprises of the healthcare as well as the administrative requirements, user stories, data-flows and associated functionality. Moreover, leveraging the HL7 Fast Healthcare Interoperability Resources (FHIR) standard we highlight the concluded interoperability framework that allows genuine cross-system communication and defines third-party systems connectivity.Clinical Relevance- This work is strongly correlated with medicine since it describes the system requirements and the architecture of a national integrated electronic health records system.- Published
- 2021
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33. A Web services-based exergaming platform for senior citizens: the Long Lasting Memories project approach to e-health care.
- Author
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Bamidis PD, Konstantinidis EI, Billis A, Frantzidis C, Tsolaki M, Hlauschek W, Kyriacou E, Neofytou M, and Pattichis CS
- Subjects
- Aged, Humans, Internet, Memory, Telemedicine
- Abstract
This piece of research describes an innovative e-health service that supports the cognitive and physical training of senior citizens and promotes their active ageing. The approach is adopted by the Long Lasting Memories (LLM) project, elements of which are discussed herein in the light of the functionalities provided to the users and the therapists. The aim of this work is to describe those technical elements that demonstrate the unique and integrative character of the LLM service, which is based on a modular Web service architecture, rendering the system available in different settings like the homes of seniors. The underlying database as well as the remote user interface empower therapists to set personalized training schemes, to view the progress of training sessions, as well as, adding new games and exercises into the system, thereby increasing the services sustainability and marketability.
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- 2011
- Full Text
- View/download PDF
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