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Darier disease is considered a hereditary acantholytic dermatosis that is inherited in an autosomal dominant manner and usually manifests in the first or second decade of life. We describe a 62-year-old man with an acquired variant of Darier disease after a recent diagnosis of metastatic prostate cancer. We discuss and postulate a novel mechanism for this unusual presentation.

Topical steroids are the mainstay of treatment in atopic dermatitis, but 60–80 per cent patients or carers have an aversion to using them due to the potential side-effects. Here, the authors discuss topical steroid phobia and the importance of communication in its management.

A 64 year old woman was referred to dermatology with a two year history of tense painful blisters, limited …