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Objectives: The coronavirus disease-2019 (COVID-19) mortality risk in males is twice as high compared to females. The literature lacks data regarding how the cardiological parameters influence the mortality rate imbalance between genders in the setting of COVID-19. This study aims to investigate how cardiological parameters vary between genders in COVID-19 disease—a potential explanation for the increased mortality rate in males in the setting of COVID-19. Materials and Methods: We included 458 adult patients with a confirmed diagnosis of COVID-19 disease. Demographics, comorbidities, laboratory findings, and electrocardiogram parameters were compared between males and females. Results: Of 458, a total of 63 (14.2%) patients died, and 82 (17.9%) were followed up in the intensive care unit during the hospitalization. Although the median age between males and females looked like to be similar, the mortality rate was significantly higher among males (44% vs 9.5%, p=0.006). High-sensitive troponin T, presentative of myocardial injury, was considerably higher in dead patients than survivors (p

Objective: It has been shown that the presence of fragmented QRS (fQRS) is associated with poor prognosis in many cardiovascular diseases and in patients with hypertrophic cardiomyopathy (HCM). However, no study has shown an association with the absolute risk score of sudden cardiac death. The aim of this study was to determine the relationship between QRS and the predicted risk score of sudden cardiac death at 5 years (HCM Risk-SCD) in HCM patients. Methods: In total, 115 consecutive HCM patients were included in this prospective observational study. The patients were divided into two groups according to the presence [fQRS(+) group (n= 65)] or absence [fQRS(-) group (n= 50)] of fQRS on a 12-lead electrocardiogram (ECG). Results: The HCM Risk-SCD (%) HCM Risk-SCD (>6%) values and some echocardiographic parameters, including ventricular extrasystole, ventricular tachycardia, cardiopulmonary resuscitation, implantable cardioverter defibrillator implantation, appropriate shock, and heart failure at the time of admission, were significantly higher in the fQRS(+) group than in the fQRS(-) group (all p4 was identified as an effective cut-off point in fQRS for HCM. An HCM Risk-SCD value of >4 yielded a sensitivity of 77% and a specificity of 76%. Conclusion: fQRS is determined to be an independent high-risk indicator of HCM Risk-SCD. It seems to be associated with increased ventricular arrhythmias and some echocardiographic parameters.