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Your search keyword '"Monno, M."' showing total 99 results
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99 results on '"Monno, M."'

29. Process parameters control in water jet peening

Author

Colosimo, B.M., Monno, M., and Semeraro, Q.

Subjects
Metal products -- Product information, Metal products -- Reports, Engineering and manufacturing industries
Abstract

Byline: B.M. Colosimo, M. Monno, Q. Semeraro Recent researches propose the use of Water Jet technology for peening metallic components. Compared with traditional shot peening (SP), water jet peening (WJP) process presents the main advantage of a negligible influence on surface roughness and topography. Nevertheless, the transition from residual stress generation to the beginning of an erosion phenomenon is deeply influenced by an accurate selection of process parameters. Since by now parameter selection is performed by experimental trials, the paper focuses on the analysis of two main parameters the pressure and the traverse rate of the waterjet. The effect of these parameters on residual stress, roughness and erosion is investigated and empirical relationships which can explain these effects are presented.

Published
2003

36. A numerical methodology to identify Process Damping in milling

Author

LEONESIO M, PITTALA' G, BIANCHI G, GOLETTI M, and MONNO M

Abstract

Chatter is a self-excited vibration that can occur during machining operations. This undesirable phenomenon is one of the most common limitations when it comes to improving productivity and part quality. Notwithstanding its importance, chatter stability analysis in metal cutting is an unsolved problem at low cutting speeds due to the Process Damping (PD) phenomenon, were vibrational energy is dissipated through impacts between tool flank and workpiece. Despite the great amount of literature on this issue, some basic claims exploited by the most widespread modelling approaches are weak and unsound. The adopted fomulations are not able to provide a reliable prediction of cutting stability limit without being tuned by adhoc experimental campaigns that usually require a complex set-up and need to be repeated for every combination of tool wear status, machined material and lubrication strategy. Such effort, typically time-consuming and requiring specialized knowledge, is usually incompatible with the industrial context. In the present article, a critical investigation on PD is carried out, analysing PD mechanics by means of FE analysis of cutting. The results lead to a new analytical formulation of PD force, more coeherent with the experiences obntained in material science field, whose generality suffices for a wide range of cases of technological interest. Besides, it is pointed out how the damping force is also influenced by tool-workpiece relative dynamics, so that the sole local mechanics of the contact between tool and workpiece cannot describe completely the real sistuations. Then, the PD model is included in a time domain milling simulation model, enabling a complete functional simulation of cutting taking into account machine-process dynamic interaction and, hence, regenerative chatter occurrence. Thereafter, for a given milling operation, the stability lobes diagram can be computed numerically, in time domain, by scanning a proper grid of spindle speeds and depths of cut; in this way, the effect of the proposed PD model can be evaluated. Finally, the proposed modelling analysis of PD is used to interpret the results of a milling tests campaign in an industrial context.

Published
2010

45. AWJ Machining: Surface Quality as a Constraint

Author

Polini, Wilma, Capello, E, Monno, M, and Semeraro, Q.

Subjects
surface quality, abrasive water jet, metallic matrix composite, abrasive water jet, surface quality, metallic matrix composite
Published
1996

49. Randomized clinical trial of robot-assisted versus laparoscopic Nissen fundoplication.

Author

Monno, M., Pellegrino, L., Giaccone, C., Garrone, C., and Rebecchi, F.

Subjects
*FUNDOPLICATION, *ESOPHAGEAL surgery, *GASTRIC fundus surgery, *MEDICAL robotics, *MEDICAL technology, *MEDICAL experimentation on humans
Abstract

The article presents a randomized study of robot-assisted versus laparoscopic Nissen fundoplication to patients undergoing laparoscopic antireflux surgery. The researchers confirmed that robot-assisted laparoscopic fundoplication was comparable to that of the standard laparoscopic procedure in terms of effects and feasibility. However, they stressed that operation costs are higher because of longer operating time and the utilization of expensive medical equipment.

Published
2006
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50. POFUT1 and PLAGL2 are characteristic markers of mucinous colorectal cancer associated with MUC2 expression.

Author

Monno M, Ogiri M, Seishima R, Suzuki Y, Hattori K, Matsui S, Shigeta K, Okabayashi K, and Kitagawa Y

Subjects
Humans, DNA-Binding Proteins metabolism, Mucin-2 genetics, Mucin-2 metabolism, RNA-Binding Proteins genetics, Transcription Factors genetics, Adenocarcinoma, Adenocarcinoma, Mucinous genetics, Adenocarcinoma, Mucinous metabolism, Adenocarcinoma, Mucinous pathology, Colorectal Neoplasms metabolism
Abstract

Colorectal mucinous adenocarcinoma (MAC) is one of the most lethal histological types of colorectal cancer, and its mechanism of development is not well understood. In this study, we aimed to clarify the molecular characteristics of MAC via in silico analysis using The Cancer Genome Atlas database. The expression of genes on chromosome 20q (Chr20q) was negatively associated with the expression of MUC2, which is a key molecule that can be used to distinguish between MAC and nonmucinous adenocarcinoma (NMAC). This was consistent with a significant difference in copy number alteration of Chr20q between the two histological types. We further identified 475 differentially expressed genes (DEGs) between MAC and NMAC, and some of the Chr20q genes among the DEGs are considered to be pivotal genes used to define MAC. Both in vitro and in vivo analysis showed that simultaneous knockdown of POFUT1 and PLAGL2, both of which are located on Chr20q, promoted MUC2 expression. Moreover, these genes were highly expressed in NMAC but not in MAC according to the results of immunohistological studies using human samples. In conclusion, POFUT1 and PLAGL2 are considered to be important for defining MAC, and these genes are associated with MUC2 expression., (© 2024 The Authors. Cell Biochemistry and Function published by John Wiley & Sons Ltd.)

Published
2024
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