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2. Formal consensus study on surgery to replace the aortic valve in adults aged 18–60 years

Author

Stoica, Serban, Beard, Chloe, Takkenberg, Johanna JM, Mokhles, Mostafa M, Turner, Mark, Pepper, John, Hopewell-Kelly, Noreen, Benedetto, Umberto, Nashef, Samer AM, El-Hamamsy, Ismail, Skillington, Peter, Glauber, Mattia, De Paulis, Ruggero, Tseng, Elaine, Meuris, Bart, Sitges, Marta, Delgado, Victoria, Krane, Markus, Kostolny, Martin, and Pufulete, Maria

Subjects
Biomedical and Clinical Sciences, Cardiovascular Medicine and Haematology, Clinical Sciences, Clinical Research, Cardiovascular, Aging, Transplantation, Heart Disease, Patient Safety, Humans, Adult, Aortic Valve, Heart Valve Prosthesis Implantation, Aortic Valve Stenosis, Autografts, Treatment Outcome, Transplantation, Autologous, Heart Valve Prosthesis, Transcatheter Aortic Valve Replacement, heart valve prosthesis, transcatheter aortic valve replacement, aortic valve insufficiency, aortic valve stenosis, heart valve prosthesis implantation, Cardiorespiratory Medicine and Haematology, Cardiovascular System & Hematology, Cardiovascular medicine and haematology, Clinical sciences
Abstract

ObjectiveThere is uncertainty about surgical procedures for adult patients aged 18-60 years undergoing aortic valve replacement (AVR). Options include conventional AVR (mechanical, mAVR; tissue, tAVR), the pulmonary autograft (Ross) and aortic valve neocuspidisation (Ozaki). Transcatheter treatment may be an option for selected patients. We used formal consensus methodology to make recommendations about the suitability of each procedure.MethodsA working group, supported by a patient advisory group, developed a list of clinical scenarios across seven domains (anatomy, presentation, cardiac/non-cardiac comorbidities, concurrent treatments, lifestyle, preferences). A consensus group of 12 clinicians rated the appropriateness of each surgical procedure for each scenario on a 9-point Likert scale on two separate occasions (before and after a 1-day meeting).ResultsThere was a consensus that each procedure was appropriate (A) or inappropriate (I) for all clinical scenarios as follows: mAVR: total 76% (57% A, 19% I); tAVR: total 68% (68% A, 0% I); Ross: total 66% (39% A, 27% I); Ozaki: total 31% (3% A, 28% I). The remainder of percentages to 100% reflects the degree of uncertainty. There was a consensus that transcatheter aortic valve implantation is appropriate for 5 of 68 (7%) of all clinical scenarios (including frailty, prohibitive surgical risk and very limited life span).ConclusionsEvidence-based expert opinion emerging from a formal consensus process indicates that besides conventional AVR options, there is a high degree of certainty about the suitability of the Ross procedure in patients aged 18-60 years. Future clinical guidelines should include the option of the Ross procedure in aortic prosthetic valve selection.

Published
2023

5. Coronary Physiological Indexes to Evaluate Myocardial Ischemia in Patients With Aortic Stenosis Undergoing Valve Replacement

Author

Minten, Lennert, McCutcheon, Keir, Vanhaverbeke, Maarten, Wouters, Laurine, Bézy, Stéphanie, Lesizza, Pierluigi, Jentjens, Sander, Frederiks, Pascal, Bringmans, Tijs, Voigt, Jens-Uwe, Adriaenssens, Tom, Desmet, Walter, Sinnaeve, Peter, Jacobs, Steven, Verbrugghe, Peter, Meuris, Bart, Janssens, Stefan, Fearon, William F., Bennett, Johan, and Dubois, Christophe

Published
2024
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8. Wall Stress Distributions in Abdominal Aortic Aneurysms Do Not Correlate With Symptoms

Author

Miller, Karol, Mufty, Hozan, Catlin, Alastair, Rogers, Christopher, Saunders, Bradley, Sciarrone, Ross, Fourneau, Inge, Meuris, Bart, Tavner, Angus, Joldes, Grand R., and Wittek, Adam

Subjects
Physics - Medical Physics
Abstract

Abdominal aortic aneurysm (AAA) is a permanent and irreversible dilation of the lower region of the aorta. It is typically an asymptomatic condition that if left untreated can expand to the point of rupture. Mechanically-speaking, rupture of an artery occurs when the local wall stress exceeds the local wall strength. It is therefore understandable that numerous studies have attempted to estimate the AAA wall stress. Recently the Intelligent Systems for Medicine Laboratory (ISML) presented a very efficient method to compute AAA wall stress using geometry from Computed Tomography (CT) images, and median arterial pressure as the applied load. The ISML's method is embedded in the software platform BioPARR - Biomechanics based Prediction of Aneurysm Rupture Risk, freely available from http://bioparr.mech.uwa.edu.au/. The uniqueness of our stress computation approach is three-fold: i) the results are insensitive to unknown patient-specific mechanical properties of arterial wall tissue; ii) the residual stress is accounted for, according to Y.C. Fung's Uniform Stress Hypothesis; and iii) the analysis is automated and quick, making our approach compatible with clinical workflows. In this study we evaluated 19 cases of AAA. A proportion of these were classified as symptomatic. The results of the analysis demonstrate, contrary to the common view, that neither the wall stress magnitude nor the stress distribution correlate with the presence of clinical symptoms., Comment: 13 pages, 5 figures 1 table

Published
2019
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10. Randomized controlled trial between conventional versus sutureless bioprostheses for aortic valve replacement: Impact of mini and full sternotomy access at 1-year follow-up

Author

Fischlein, Theodor, Caporali, Elena, Folliguet, Thierry, Kappert, Utz, Meuris, Bart, Shrestha, Malakh L., Roselli, Eric E., Bonaros, Nikolaos, Fabre, Olivier, Corbi, Pierre, Troise, Giovanni, Andreas, Martin, Pinaud, Frederic, Pfeiffer, Steffen, Kueri, Sami, Tan, Erwin, Voisine, Pierre, Girdauskas, Evaldas, Rega, Filip, García-Puente, Julio, and Lorusso, Roberto

Published
2022
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11. Midterm outcomes with a sutureless aortic bioprosthesis in a prospective multicenter cohort study

Author

Zannis, Kostantinos, Pfeiffer, Steffen, Santarpino, Giuseppe, Shrestha, Malakh, Sarikouch, Samir, Gummert, Jan F., Mohr, Friedrich W., Dohmen, Pascal, Stalder, Mario, Roost, Eva, Filipiak, Krzysztof, Niklewski, Tomasz, Madonna, Francesco, Roques, Xavier, Flameng, Willem J., Laczkovics, Axel M.M., Bechtel, Matthias, Prat, Alain G., Banfi, Carlo, Dapunt, Otto E., Eichstaedt, Harald C., Harringer, Wolfgang, Carstens-Fitz, Ulrike, Spyt, Tom J., Wimmer-Greinecker, Jan Gerhard, Machner, Matthias, Tan, Erwin S.H., Casselman, Filip P.A., Yilmaz, Alaaddin, Sonker, Uday, Bleiziffer, Sabine, Oberwalder, Peter J., Kocher, Alfred A., Seitelberger, Rainald, Treede, Hendrik, Conradi, Leonard, Cocchieri, Riccardo, De Mol, Bas, Roussel, Jean-Christian, Despins, Philippe, Jakob, Heinz G., Wendt, Daniel, Fischlein, Theodor, Meuris, Bart, Folliguet, Thierry, Hakim-Meibodi, Kavous, Misfeld, Martin, Carrel, Thierry, Zembala, Marian, Cerutti, Elisa, Asch, Federico M., and Haverich, Axel

Published
2022
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12. Sutureless Versus Rapid Deployment Aortic Valve Replacement: Results From a Multicenter Registry

Author

Berretta, Paolo, Meuris, Bart, Kappert, Utz, Andreas, Martin, Fiore, Antonio, Solinas, Marco, Misfeld, Martin, Carrel, Thierry P., Villa, Emmanuel, Savini, Carlo, Santarpino, Giuseppe, Teoh, Kevin, Albertini, Alberto, Fischlein, Theodor, Martinelli, Gianluca, Mignosa, Carmelo, Glauber, Mattia, Shrestha, Malak, Laufer, Ghunter, Phan, Kevin, Yan, Tristan, and Di Eusanio, Marco

Published
2022
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15. An interventional sheep model of severe aortic valve stenosis hemodynamics for the evaluation of alterations in coronary physiology and microvascular function

Author

Minten, Lennert, primary, Langenaeken, Tom, additional, McCutcheon, Keir, additional, Bennett, Johan, additional, Van Hecke, Manon, additional, Algoet, Michiel, additional, Bézy, Stéphanie, additional, Duchenne, Jürgen, additional, Puvrez, Alexis, additional, Wouters, Laurine, additional, Voigt, Jens-Uwe, additional, Adriaenssens, Tom, additional, Desmet, Walter, additional, Sinnaeve, Peter, additional, Verbrugghe, Peter, additional, Oosterlinck, Wouter, additional, Claus, Piet, additional, Meuris, Bart, additional, and Dubois, Christophe, additional

Published
2024
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20. Long-term outcome after the Ross procedure in 173 adults with up to 25 years of follow-up.

Author

Hoof, Lucas Van, Rooyackers, Bert, Schuermans, Art, Duponselle, Jolien, Bruaene, Alexander Van De, Meester, Pieter De, Troost, Els, Meuris, Bart, Budts, Werner, Gewillig, Marc, Flameng, Willem, Daenen, Willem, Meyns, Bart, Verbrugghe, Peter, and Rega, Filip

Subjects
AORTIC valve diseases, YOUNG adults, AORTIC valve insufficiency, UNIVERSITY hospitals, REGRESSION analysis
Abstract

OBJECTIVES The potential risk of autograft dilatation and homograft stenosis after the Ross procedure mandates lifelong follow-up. This retrospective cohort study aimed to determine long-term outcome of the Ross procedure, investigating autograft and homograft failure patterns leading to reintervention. METHODS All adults who underwent the Ross procedure between 1991 and 2018 at the University Hospitals Leuven were included, with follow-up data collected retrospectively. Autograft implantation was performed using the full root replacement technique. The primary end-point was long-term survival. Secondary end-points were survival free from any reintervention, autograft or homograft reintervention-free survival, and evolution of autograft diameter, homograft gradient and aortic regurgitation grade over time. RESULTS A total of 173 adult patients (66% male) with a median age of 32 years (range 18–58 years) were included. External support at both the annulus and sinotubular junction was used in 38.7% (67/173). Median follow-up duration was 11.1 years (IQR, 6.4–15.9; 2065 patient-years) with 95% follow-up completeness. There was one (0.6%) perioperative death. Kaplan–Meier estimate for 15-year survival was 91.1% and Ross-related reintervention-free survival was 75.7% (autograft: 83.5%, homograft: 85%). Regression analyses demonstrated progressive neoaortic root dilatation (0.56 mm/year) and increase in homograft gradient (0.72 mmHg/year). CONCLUSIONS The Ross procedure has the potential to offer excellent long-term survival and reintervention-free survival. These long-term data further confirm that the Ross procedure is a suitable option in young adults with aortic valve disease which should be considered on an individual basis. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Early outcomes of aortic valve replacement with Perceval PLUS sutureless valve: results of the prospective multicentric MANTRA study.

Author

Micovic, Slobodan, Nobre, Angelo, Choi, Jae Woong, Solinas, Marco, Shehada, Sharaf-Eldin, Torella, Michele, Baeza, Cristian, Parrino, Eugene, Pollari, Francesco, Troise, Giovanni, Kappert, Utz, Mellert, Friedrich, Je, Hyung Gon, Argano, Vincenzo, Lam, Ka Yan, Rinaldi, Mauro, Gutermann, Herbert, and Meuris, Bart

Subjects
AORTIC valve transplantation, PERCUTANEOUS balloon valvuloplasty, HEART valve prosthesis implantation, FUNCTIONAL status, INTERNATIONAL agencies
Abstract

Background: The aim of this study is to report the preliminary real-word clinical and hemodynamic performance from the MANTRA study in patients undergoing aortic valve replacement with Perceval PLUS sutureless valve. Methods: MANTRA is an ongoing "umbrella" prospective, multi-center, international post-market study to collect real-life safety and performance data on Corcym devices (Corcym S.r.l, Saluggia, Italy). Clinical and echocardiographic outcomes were collected preoperatively, at discharge and at each follow up. KCCQ-12 and EQ-5D-5L quality of life questionnaires were collected preoperatively and at 30-days. Results: A total of 328 patients underwent aortic valve replacement with Perceval PLUS in 29 International institutions. Patients were enrolled from July 2021 to October 2023 and enrollment is still ongoing. Mean age was 71.9 ± 6.4 years, mean EuroSCORE II was 2.9 ± 3.9. Minimally invasive approach was performed in 44.2% (145/328) of patients; concomitant procedures were done in 40.8% (134/328) of cases. Thirty-day mortality was 1.8% (6/328) and no re-interventions were reported. Pacemaker implant was required in 4.0% (13/328) of the patients. The assessment of the functional status demonstrated marked and stable improvement in NYHA class in most patients at 30-day follow-up, with significant increase of KCCQ-12 summary score (from 58.8 ± 23.0 to 71.8 ± 22.1, p < 0.0001) and EQ-5D-5L VAS score (from 64.5 ± 20.4 to 72.6 ± 17.5, p < 0.0001). Mean pressure gradient decreased from 46.2 ± 17.3 mmHg to 10.1 ± 4.7 mmHg at 30-day follow-up. Low or no incidence of moderate-to-severe paravalvular or central leak was reported. Conclusions: Preliminary results demonstrate good clinical outcomes and significant improvement of Quality of Life at 30-days, excellent early hemodynamic performance within patient implanted with Perceval PLUS. Trial Registration: The MANTRA study has been registered in ClinicalTrials.gov (NCT05002543, Initial release 26 July 2021). [ABSTRACT FROM AUTHOR]

Published
2024
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25. Correction to: European registry of type A aortic dissection (ERTAAD) - rationale, design and definition criteria

Author

Biancari, Fausto, Mariscalco, Giovanni, Yusuff, Hakeem, Tsang, Geoffrey, Luthra, Suvitesh, Onorati, Francesco, Francica, Alessandra, Rossetti, Cecilia, Perrotti, Andrea, Chocron, Sidney, Fiore, Antonio, Folliguet, Thierry, Pettinari, Matteo, Dell’Aquila, Angelo M., Demal, Till, Conradi, Lenard, Detter, Christian, Pol, Marek, Ivak, Peter, Schlosser, Filip, Forlani, Stefano, Chetty, Govind, Harky, Amer, Kuduvalli, Manoj, Field, Mark, Vendramin, Igor, Livi, Ugolino, Rinaldi, Mauro, Ferrante, Luisa, Etz, Christian, Noack, Thilo, Mastrobuoni, Stefano, De Kerchove, Laurent, Jormalainen, Mikko, Laga, Steven, Meuris, Bart, Schepens, Marc, Dean, Zein El, Vento, Antti, Raivio, Peter, Borger, Michael, and Juvonen, Tatu

Published
2021
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27. European registry of type A aortic dissection (ERTAAD) - rationale, design and definition criteria

Author

Biancari, Fausto, Mariscalco, Giovanni, Yusuff, Hakeem, Tsang, Geoffrey, Luthra, Suvitesh, Onorati, Francesco, Francica, Alessandra, Rossetti, Cecilia, Perrotti, Andrea, Chocron, Sidney, Fiore, Antonio, Folliguet, Thierry, Pettinari, Matteo, Dell’Aquila, Angelo M., Demal, Till, Conradi, Lenard, Detter, Christian, Pol, Marek, Ivak, Peter, Schlosser, Filip, Forlani, Stefano, Chetty, Govind, Harky, Amer, Kuduvalli, Manoj, Field, Mark, Vendramin, Igor, Livi, Ugolino, Rinaldi, Mauro, Ferrante, Luisa, Etz, Christian, Noack, Thilo, Mastrobuoni, Stefano, De Kerchove, Laurent, Jormalainen, Mikko, Laga, Steven, Meuris, Bart, Schepens, Marc, El Dean, Zein, Vento, Antti, Raivio, Peter, Borger, Michael, and Juvonen, Tatu

Published
2021
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28. AVIATOR: An open international registry to evaluate medical and surgical outcomes of aortic valve insufficiency and ascending aorta aneurysm

Author

Dinges, Christian, Steindl, Johannes, Ziller, Rosina, De Kerchove, Laurent, Benkacem, Taoufik, Coulon, Corinne, Elkhoury, Gebrine, Kaddouri, Fadoua, Vanoverschelde, Jean-Louis, de Meester, Christophe, Pasquet, Agnès, Nijs, Jan, Van Mosselvelde, Veerle, Loeys, Bart, Meuris, Bart, Schepmans, Evi, Van den Bossche, Klaartje, Verbrugghe, Peter, Goossens, Wenke, Gutermann, Herbert, Pettinari, Matteo, El-Hamamsy, Ismail, Lenoir, Marien, Noly, Pierre-Emmanuel, Tousch, Michael, Shah, Pallav, Boodhwani, Munir, Rudez, Igor, Baric, Davor, Unic, Daniel, Varvodic, Josip, Gjorgijevska, Savica, Vojacek, Jan, Zacek, Pavel, Karalko, Mikita, Hlubocky, Jaroslav, Novotny, Robert, Slautin, Andrey, Soliman, Said, Arnaud-Crozat, Eric, Boignard, Aude, Fayad, Georges, Bouchot, Olivier, Albat, Bernard, Leguerrier, Alain, Doguet, Fabien, Fuzellier, Jean-François, Glock, Yves, Jondeau, Guillaume, Fernandez, Guy, Chatel, Didier, Zeitoun, David Messika, Jouan, Jérôme, Di Centa, Isabelle, Obadia, Jean-François, Leprince, Pascal, Houel, Rémi, Bergoend, Eric, Lopez, Stéphane, Berrebi, Alain, Tubach, Florence, Lansac, Emmanuel, Lejeune, Stéphanie, Monin, Jean-Luc, Pousset, Sarah, Mankoubi, Leila, Noghin, Milean, Diakov, Christelle, Czytrom, Daniel, Schäfers, Hans-Joachim, Borger, Michael, Aicher, Diana, Theisohn, Frank, Ferrero, Paolo, Stoica, Serban, Matuszewski, Maciej, Yiu, Patrick, Bashir, Mohamad, Ceresa, Fabrizio, Patane, Francesco, De Paulis, Ruggero, Chirichilli, Ilaria, Masat, Mauro, Antona, Carlo, Contino, Monica, Mangini, Andrea, Romagnoni, Claudia, Grigioni, Francesco, Rosa, Rubina, Okita, Yutaka, Miyairi, Takeshi, Kunihara, Takashi, de Heer, Frederiek, Koolbergen, Dave, Marsman, Mandy, Gökalp, Arjen, Kluin, Jolanda, Bekkers, Jos, Duininck, Liesbeth, Takkenberg, Johanna J.M., Klautz, Robert, Van Brakel, Thomas, Arabkhani, Bardia, Mecozzi, Gianclaudio, Accord, Ryan, Jasinski, Marek, Aminov, Vladislav, Svetkin, Mihail, Kolesar, Adrian, Sabol, František, Toporcer, Tomas, Bibiloni, Ignacio, Rábago, Gregorio, Alvarez-Asiain, Virginia, Melero, Amaia, Sadaba, Rafael, Aramendi, José, Crespo, Alejandro, Porras, Carlos, Evangelista Masip, Arturo, Kelley, Shelagh, Bavaria, Joseph, Milewski, Rita, Moeller, Patrick, Wenger, Isaac, Enriquez-Sarano, Maurice, Alger, Stan, Alger, Aurelie, and Leavitt, Katie

Published
2019
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29. Aortic Valve Surgery in Nonelderly Patients: Insights Gained From AVIATOR

Author

Dinges, Christian, Steindl, Johannes, Ziller, Rosina, Benkacem, Taoufik, Coulon, Corinne, Kaddouri, Fadoua, de Meester, Christophe, Pasquet, Agnès, Nijs, Jan, Van Mossevelde, Veerle, Loeys, Bart, Meuris, Bart, Schepmans, Evi, Van den Bossche, Klaartje, Verbrugghe, Peter, Goossens, Wenke, Gutermann, Herbert, Pettinari, Matteo, Lenoir, Marien, Noly, Pierre-Emmanuel, Tousch, Michael, Shah, Pallav, Boodhwani, Munir, Rudez, Igor, Baric, Davor, Unic, Daniel, Varvodic, Josip, Gjorgijevska, Savica, Vojacek, Jan, Zacek, Pavel, Karalko, Mikita, Hlubocky, Jaroslav, Novotny, Robert, Slautin, Andrey, Soliman, Said, Arnaud-Crozat, Eric, Boignard, Aude, Fayad, Georges, Bouchot, Olivier, Albat, Bernard, Leguerrier, Alain, Doguet, Fabien, Fuzellier, Jean-François, Glock, Yves, Fernandez, Guy, Chatel, Didier, Zeitoun, David Messika, Jouan, Jérôme, Di Centa, Isabelle, Obadia, Jean-François, Leprince, Pascal, Houel, Rémi, Bergoend, Eric, Lopez, Stéphane, Berrebi, Alain, Tubach, Florence, Monin, Jean-Luc, Pousset, Sarah, Mankoubi, Leila, Noghin, Milean, Diakov, Christelle, Czytrom, Daniel, Borger, Michael, Aicher, Diana, Rauch, Svenja, Theisohn, Frank, Ferrero, Paolo, Stoica, Serban, Matuszewski, Maciej, Yiu, Patrick, Bashir, Mohamad, Ceresa, Fabrizio, Patane, Francesco, De Paulis, Ruggero, Chirichilli, Ilaria, Masat, Mauro, Antona, Carlo, Contino, Monica, Mangini, Andrea, Romagnoni, Claudia, Grigioni, Francesco, Rosa, Rubina, Okita, Yutaka, Miyairi, Takeshi, Kunihara, Takashi, Koolbergen, Dave, Bekkers, Jos, Klautz, Robert, Van Brakel, Thomas, Arabkhani, Bardia, Mecozzi, Gianclaudio, Accord, Ryan, Jasinski, Marek, Aminov, Vladislav, Svetkin, Mihail, Kolesar, Adrian, Sabol, František, Toporcer, Tomas, Bibiloni, Ignacio, Rábago, Gregorio, Alvarez-Asiain, Virginia, Melero, Amaia, Sadaba, Rafael, Aramendi, José, Crespo, Alejandro, Porras, Carlos, Masip, Arturo Evangelista, Milewski, Rita, Moeller, Patrick, Wenger, Isaac, Leon, Christine, Marnette, Jean Marc, Doisy, Vincent, Wautot, Fabrice, Bourguignon, Thierry, Cameron, Duke, Chen, Edward, Lansac, Emmanuel, Youssefi, Pouya, de Heer, Frederiek, Bavaria, Joseph, De Kerchove, Laurent, El-Hamamsy, Ismail, Elkhoury, Gebrine, Enriquez-Sarano, Maurice, Jondeau, Laurent de Guillaume, Kluin, Jolanda, Pibarot, Philippe, Schäfers, Hans-Joachim, Vanoverschelde, Jean-Louis, and Takkenberg, Johanna J.M.

Published
2019
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35. Optimal Measurement of Coronary Flow and Microvascular Function in Animals and Humans

Author

Minten, Lennert, primary, Algoet, Michiel, additional, Bennett, Johan, additional, Oosterlinck, Wouter, additional, Meuris, Bart, additional, Langenaeken, Tom, additional, Bézy, Stephanie, additional, Wouters, Laurine, additional, Duchenne, Jürgen, additional, Puvrez, Alexis, additional, De Groote, Senne, additional, Lesizza, Pierluigi, additional, Frederiks, Pascal, additional, De Vos, Laurens, additional, Adriaenssens, Tom, additional, Sinnaeve, Peter, additional, Desmet, Walter, additional, McCutcheon, Keir, additional, and Dubois, Christophe, additional

Published
2023
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40. Cardiac Microvascular Endothelial Cells in Pressure Overload–Induced Heart Disease

Author

Trenson, Sander, Hermans, Hadewich, Craps, Sander, Pokreisz, Peter, de Zeeuw, Pauline, Van Wauwe, Jore, Gillijns, Hilde, Veltman, Denise, Wei, Fangfei, Caluwé, Ellen, Gijsbers, Rik, Baatsen, Pieter, Staessen, Jan A., Ghesquiere, Bart, Carmeliet, Peter, Rega, Filip, Meuris, Bart, Meyns, Bart, Oosterlinck, Wouter, Duchenne, Jürgen, Goetschalckx, Kaatje, Voigt, Jens-Uwe, Herregods, Marie-Christine, Herijgers, Paul, Luttun, Aernout, and Janssens, Stefan

Published
2021
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43. Durability of bioprosthetic aortic valve replacement in patients under the age of 60 years – 1-year follow-up from the prospective INDURE registry

Author

Meuris, Bart, primary, Roussel, Jean-Christian, additional, Borger, Michael A, additional, Siepe, Matthias, additional, Stefano, Pierluigi, additional, Laufer, Günther, additional, Langanay, Thierry, additional, Theron, Alexis, additional, Grabenwöger, Martin, additional, Binder, Konrad, additional, Demers, Philippe, additional, Pessotto, Renzo, additional, van Leeuwen, Wouter, additional, Bourguignon, Thierry, additional, Canovas, Sergio, additional, Mariscalco, Giovanni, additional, Coscioni, Enrico, additional, Dagenais, Francois, additional, Wendler, Olaf, additional, Polvani, Gianluca, additional, Eden, Matthias, additional, Botta, Beate, additional, Bramlage, Peter, additional, and De Paulis, Ruggero, additional

Published
2023
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44. Durability of bioprosthetic aortic valves in patients under the age of 60 years – rationale and design of the international INDURE registry

Author

Meuris, Bart, Borger, Michael A., Bourguignon, Thierry, Siepe, Matthias, Grabenwöger, Martin, Laufer, Günther, Binder, Konrad, Polvani, Gianluca, Stefano, Pierluigi, Coscioni, Enrico, van Leeuwen, Wouter, Demers, Philippe, Dagenais, Francois, Canovas, Sergio, Theron, Alexis, Langanay, Thierry, Roussel, Jean-Christian, Wendler, Olaf, Mariscalco, Giovanni, Pessotto, Renzo, Botta, Beate, Bramlage, Peter, and de Paulis, Ruggero

Published
2020
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48. The rise of new technologies for aortic valve stenosis: A comparison of sutureless and transcatheter aortic valve implantation

Author

D'Onofrio, Augusto, Salizzoni, Stefano, Rubino, Antonino S., Besola, Laura, Filippini, Claudia, Alfieri, Ottavio, Colombo, Antonio, Agrifoglio, Marco, Fischlein, Theodor, Rapetto, Filippo, Tarantini, Giuseppe, Dalèn, Magnus, Gabbieri, Davide, Meuris, Bart, Savini, Carlo, Gatti, Giuseppe, Aiello, Marco Luigi, Biancari, Fausto, Livi, Ugolino, Stefàno, Pier Luigi, Cassese, Mauro, Borrello, Bruno, Rinaldi, Mauro, Mignosa, Carmelo, and Gerosa, Gino

Published
2016
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49. The sutureless aortic valve at 1 year: A large multicenter cohort study

Author

Folliguet, Thierry, Zannis, Kostantinos, Pfeiffer, Steffen, Santarpino, Giuseppe, Shrestha, Malakh, Sarikouch, Samir, Gummert, Jan F., Mohr, Friedrich W., Dohmen, Pascal, Stalder, Mario, Roost, Eva, Filipiak, Krzysztof, Niklewski, Tomasz, Roques, Xavier, Flameng, Willem J., Laczkovics, Axel M.M., Bechtel, Matthias, Prat, Alain G., Banfi, Carlo, Dapunt, Otto E., Eichstaedt, Harald C., Harringer, Wolfgang, Carstens-Fitz, Ulrike, Spyt, Tom J., Wimmer-Greinecker, Jan Gerhard, Machner, Matthias, Tan, Erwin S.H., Casselman, Filip P.A., Yilmaz, Alaaddin, Sonker, Uday, Bleiziffer, Sabine, Oberwalder, Peter J., Kocher, Alfred A., Seitelberger, Rainald, Treede, Hendrik, Conradi, Leonard, Cocchieri, Riccardo, De Mol, Bas, Roussel, Jean-Christian, Despins, Philippe, Jakob, Heinz G., Wendt, Daniel, Fischlein, Theodor, Meuris, Bart, Hakim-Meibodi, Kavous, Misfeld, Martin, Carrel, Thierry, Zembala, Marian, Gaggianesi, Sara, Madonna, Francesco, Laborde, François, Asch, Federico, and Haverich, Axel

Published
2016
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50. Pacemaker after Sutureless and Rapid-Deployment Prostheses: A Progress Report from the SURD-IR.

Author

Pollari, Francesco, Berretta, Paolo, Albertini, Alberto, Carrel, Thierry, Teoh, Kevin, Meuris, Bart, Villa, Emmanuel, Kappert, Utz, Andreas, Martin, Solinas, Marco, Misfeld, Martin, Savini, Carlo, Fiore, Antonio, Shrestha, Malakh, Santarpino, Giuseppe, Martinelli, Gian Luca, Mignosa, Carmelo, Glauber, Mattia, Yan, Tristan, and Fischlein, Theodor

Subjects
AORTIC valve transplantation, AORTIC valve, MITRAL valve, PROSTHETICS, CARDIOPULMONARY bypass, ARTIFICIAL implants, THORACOTOMY
Abstract

Objectives The aim of this study was to investigate the need for postoperative permanent pacemaker implantation (PPI) following sutureless and rapid-deployment aortic valve replacement (SuRD-AVR) in the context of a progress report from a large multicenter international registry (SURD-IR). Methods We retrospectively analyzed 4,166 patients who underwent SuRD-AVR between 2008 and 2019. The primary outcome was the need for PPI before discharge. The study population was analyzed separately according to the implanted prostheses (Su cohort and RD cohort). Each cohort was divided into two groups based on the operation date: an early group ("EG" = 2008–2016) and a late group ("LG" = 2017–2019). Results The rate of PPI decreased significantly in the Su cohort over time (EG = 10.8% vs LG = 6.3%, p < 0.001). In the Su cohort, a decrease in age, risk profile, and incidence of bicuspid aortic valve, increased use of anterior right thoracotomy, reduction of cardiopulmonary bypass time and of associated procedures, and more frequent use of smaller prostheses were observed over time. In the RD cohort, the rate of PPI was stable over time (EG = 8.8% vs LG = 9.3%, p = 0.8). In this cohort, a younger age, lower risk profile, and higher incidence of concomitant septal myectomy were observed over time. Conclusion Our analysis showed a significant decrease in the PPI rate in patients who underwent Su-AVR over time. Patient selection as well as surgical improvements and a more accurate sizing could be correlated with this phenomenon. The RD cohort revealed no significant differences either in patient's characteristics or in PPI rate between the two time periods. [ABSTRACT FROM AUTHOR]

Published
2023
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