701 results on '"Metzger, Joseph M."'
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2. Molecular homing and retention of muscle membrane stabilizing copolymers by non-invasive optical imaging in vivo
3. The road to physiological maturation of stem cell-derived cardiac muscle runs through the sarcomere
4. Sarcomere dynamics revealed by a myofilament integrated FRET-based biosensor in live skeletal muscle fibers
5. Sarcomere integrated biosensor detects myofilament-activating ligands in real time during twitch contractions in live cardiac muscle
6. Social stress is lethal in the mdx model of Duchenne muscular dystrophy
7. Inducing positive inotropy in human iPSC-derived cardiac muscle by gene editing-based activation of the cardiac α-myosin heavy chain
8. Cardiac myocyte intrinsic contractility and calcium handling deficits underlie heart organ dysfunction in murine cancer cachexia
9. Original article - Cytoplasmic nucleic acid-based XNAs directly enhance live cardiac cell function by a Ca2+ cycling-independent mechanism via the sarcomere
10. Cardiac Muscle Membrane Stabilization in Myocardial Reperfusion Injury
11. Molecular Mechanism of Sarcomeric Cardiomyopathies
12. Abstract P1022: Synthetic Copolymer-Based Membrane Stabilizers Confer Protection To Dystrophin-Deficient Striated Muscle In Vitro And In Vivo
13. Duchenne muscular dystrophy: disease mechanism and therapeutic strategies
14. Melanin-Concentrating Hormone 1 Receptor-Deficient Mice are Lean, Hyperactive, and Hyperphagic and Have Altered Metabolism
15. Investigations of an inducible intact dystrophin gene excision system in cardiac and skeletal muscle in vivo
16. Gene Transfer of Calcium-Binding Proteins into Adult Cardiac Myocytes
17. Parvalbumin Gene Transfer Corrects Diastolic Dysfunction in Diseased Cardiac Myocytes
18. Thin Filament Protein Dynamics in Fully Differentiated Adult Cardiac Myocytes: Toward A Model of Sarcomere Maintenance
19. Ca2+ Regulation of the Cardiac Thin Filament
20. Growth and Muscle Defects in Mice Lacking Adult Myosin Heavy Chain Genes
21. Slow Skeletal Troponin I Gene Transfer, Expression, and Myofilament Incorporation Enhances Adult Cardiac Myocyte Contractile Function
22. Gene Transfer into Mouse Embryonic Stem Cell-Derived Cardiac Myocytes Mediated by Recombinant Adenovirus
23. Intracoronary Poloxamer 188 Prevents Reperfusion Injury in a Porcine Model of ST-Segment Elevation Myocardial Infarction
24. Microtubule-Mediated Misregulation of Junctophilin-2 Underlies T-Tubule Disruptions and Calcium Mishandling in mdx Mice
25. Bundled postconditioning therapies improve hemodynamics and neurologic recovery after 17 min of untreated cardiac arrest
26. Cardiac Sarcomere Signaling in Health and Disease
27. Additional file 1 of Rapid restitution of contractile dysfunction by synthetic copolymers in dystrophin-deficient single live skeletal muscle fibers
28. Innovations in Twenty-First Century Cardiovascular Medicine
29. Differential effects of S100 proteins A2 and A6 on cardiac Ca2 + cycling and contractile performance
30. Uncoupling of increased cellular oxidative stress and myocardial ischemia reperfusion injury by directed sarcolemma stabilization
31. Duchenne muscular dystrophy: disease mechanism and therapeutic strategies.
32. Muscle membrane integrity in Duchenne muscular dystrophy: recent advances in copolymer-based muscle membrane stabilizers
33. Abstract P2069: In Vivo Investigation Of The Mechanisms Regulating Truncated Dystrophin Protein Turnover In The Heart
34. Abstract P1063: Investigation Of Synthetic Membrane-stabilizing Copolymers To Dystrophin-deficient Skeletal Muscle Fibers
35. Abstract P2038: Synthetic Membrane Stabilizers Reduce Serum Ck And Immune Cell Infiltrate In Neonatal Mdx Skeletal Muscle Prior To Overt Muscle Necrosis Onset In Vivo
36. Abstract P1057: Implementing A Novel FRET-Based Myofilament Activation Biosensor To Interrogate Dynamic Cardiac Sarcomere Performance With Small Molecule And Genetic Manipulations During A Physiological Twitch
37. Gene Transfer of Troponin I Isoforms, Mutants, and Chimeras
38. Maintaining the Fully Differentiated Cardiac Sarcomere
39. The design and synthesis of potent, selective benzodiazepine sulfonamide bombesin receptor subtype 3 (BRS-3) agonists with an increased barrier of atropisomerization
40. KCNQ Potassium Channel Mutations Cause Cardiac Arrhythmias in Drosophila That Mimic the Effects of Aging
41. Regulation of Energy Homeostasis by Bombesin Receptor Subtype-3: Selective Receptor Agonists for the Treatment of Obesity
42. Abstract 123: Study Of The Role Of Myosin-binding Protein C In The Structure-function Of Intact Cardiac Muscles Through The Use Of A Sarcomere Activation Biosensor
43. Cardiac Consequences to Skeletal Muscle-Centric Therapeutics for Duchenne Muscular Dystrophy
44. Transition in Cardiac Contractile Sensitivity to Calcium during the in vitro Differentiation of Mouse Embryonic Stem Cells
45. Chemical, Biochemical, Pharmacokinetic, and Biological Properties of L-680, 833: A Potent, Orally Active Monocyclic β-Lactam Inhibitor of Human Polymorphonuclear Leukocyte Elastase
46. Noncanonical EF-hand motif strategically delays [Ca.sup.2+] buffering to enhance cardiac performance
47. Oxidative stress pathogenically remodels the cardiac myocyte cytoskeleton via structural alterations to the microtubule lattice
48. Characterization of a novel and selective cannabinoid CB 1 receptor inverse agonist, Imidazole 24b, in rodents
49. Body temperature as a mouse pharmacodynamic response to bombesin receptor subtype-3 agonists and other potential obesity treatments
50. Chronic administration of membrane sealant prevents severe cardiac injury and ventricular dilatation in dystrophic dogs
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