234 results on '"McClenaghan, Neville H."'
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2. NKCC transport mediates the insulinotropic effects of taurine and other small neutral amino acids
3. Short-term CFTR inhibition reduces islet area in C57BL/6 mice
4. Taurine rescues pancreatic β‐cell stress by stimulating α‐cell transdifferentiation
5. Nutrient Regulation of Insulin Secretion and β-Cell Functional Integrity
6. Islet-intrinsic effects of CFTR mutation
7. Pseudoislet formation enhances gene expression, insulin secretion and cytoprotective mechanisms of clonal human insulin-secreting 1.1B4 cells
8. Evaluation of the role of N-methyl-D-aspartate (NMDA) receptors in insulin secreting beta-cells
9. Differential molecular and cellular responses of GLP-1 secreting L-cells and pancreatic alpha cells to glucotoxicity and lipotoxicity
10. Deleterious Effects of Supplementation with Dehydroepiandrosterone Sulphate or Dexamethasone on Rat Insulin-Secreting Cells Under In Vitro Culture Condition
11. Correction to: Islet-intrinsic effects of CFTR mutation
12. Effects of lipotoxicity on a novel insulin-secreting human pancreatic β-cell line, 1.1B4
13. Engineering cultured insulin-secreting pancreatic B-cell lines
14. Acute and long-term effects of metformin on the function and insulin secretory responsiveness of clonal β-cells
15. Physiological regulation of the pancreatic β-cell: functional insights for understanding and therapy of diabetes
16. Investigation of the effects of sulfonylurea exposure on pancreatic beta cell metabolism
17. A stable analogue of glucose-dependent insulinotropic polypeptide, GIP(LysPAL16), enhances functional differentiation of mouse embryonic stem cells into cells expressing islet-specific genes and hormones
18. Determining the relationship between dietary carbohydrate intake and insulin resistance
19. Alterations of insulin secretion following long-term manipulation of ATP-sensitive potassium channels by diazoxide and nateglinide
20. Chronic exposure to tolbutamide and glibenclamide impairs insulin secretion but not transcription of K ATP channel components
21. Chronic exposure to tolbutamide and glibenclamide impairs insulin secretion but not transcription of KATP channel components
22. ATP-Sensitive Potassium Channels and Efaroxan-Induced Insulin Release in the Electrofusion-Derived BRIN-BD11 β-Cell Line
23. Cystic Fibrosis–Related Diabetes: Pathophysiology and Therapeutic Challenges
24. Glycation of Insulin in the Islets of Langerhans of Normal and Diabetic Animals
25. Characterization of a Novel Glucose-Responsive Insulin-Secreting Cell Line, BRIN-BD11, Produced by Electrofusion
26. Stimulation of insulin secretion in clonal BRIN-BD11 cells by the imidazoline derivatives KU14r and RX801080
27. Desensitization of sulphonylurea- and nutrient-induced insulin secretion following prolonged treatment with glibenclamide
28. Molecular Mechanisms of Toxicity and Cell Damage by Chemicals in a Human Pancreatic Beta Cell Line, 1.1B4
29. Improved antioxidative defence protects insulin-producing cells against homocysteine toxicity
30. Implanting 1.1B4 human β-cell pseudoislets improves glycaemic control in diabetic severe combined immune deficient mice
31. Stem Cell-Based Approaches for the Treatment of Diabetes
32. ATP-Sensitive Potassium Channels and Efaroxan-Induced Insulin Release in the Electrofusion-Derived BRIN-BD 11 [Beta]-Cell Line
33. Responses of GLP1-secreting L-cells to cytotoxicity resemble pancreatic β-cells but not α-cells
34. Mechanisms of toxicity by proinflammatory cytokines in a novel human pancreatic beta cell line, 1.1B4
35. Cellular responses of novel human pancreatic β-cell line, 1.1B4 to hyperglycemia
36. Physiological concentrations of interleukin-6 directly promote insulin secretion, signal transduction, nitric oxide release, and redox status in a clonal pancreatic β-cell line and mouse islets
37. Configuration of electrofusion-derived human insulin-secreting cell line as pseudoislets enhances functionality and therapeutic utility
38. l-Arginine is essential for pancreatic β-cell functional integrity, metabolism and defense from inflammatory challenge
39. Development and Functional Characterization of Insulin-releasing Human Pancreatic Beta Cell Lines Produced by Electrofusion
40. Role of islet structure and cellular interactions in the control of insulin secretion
41. Comparison of Insulin Release From MIN6 Pseudoislets and Pancreatic Islets of Langerhans Reveals Importance of Homotypic Cell Interactions
42. The role of glucagon- and somatostatin-secreting cells in the regulation of insulin release and beta-cell function in heterotypic pseudoislets
43. Cell-to-cell communication and cellular environment alter the somatostatin status of delta cells
44. Overexpression of the malate–aspartate NADH shuttle member Aralar1 in the clonal β-cell line BRIN-BD11 enhances amino-acid-stimulated insulin secretion and cell metabolism
45. Toll-like receptor agonist induced changes in clonal rat BRIN-BD11 β-cell insulin secretion and signal transduction
46. Prolonged L-alanine exposure induces changes in metabolism, Ca2+ handling and desensitization of insulin secretion in clonal pancreatic β-cells
47. Pro-inflammatory cytokines increase glucose, alanine and triacylglycerol utilization but inhibit insulin secretion in a clonal pancreatic β-cell line
48. Major metabolic homocysteine-derivative, homocysteine thiolactone, exerts changes in pancreatic β-cell glucose-sensing, cellular signal transduction and integrity
49. Homocysteine-Induced Impairment of Insulin Secretion From Clonal Pancreatic BRIN-BD11 β-Cells Is Not Prevented by Catalase
50. Prolonged exposure to homocysteine results in diminished but reversible pancreatic β‐cell responsiveness to insulinotropic agents
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