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2. Review article: test and treat or test and scope for Helicobacter pylori infection. Any change in gastric cancer prevention?

Author

Mc Loughlin RM, Sebastian SS, O'Connor HJ, Buckley M, and O'Morain CA

Subjects
Helicobacter Infections genetics, Helicobacter Infections prevention & control, Mass Screening methods, Stomach Neoplasms genetics, Stomach Neoplasms microbiology, Helicobacter Infections complications, Helicobacter pylori genetics, Stomach Neoplasms prevention & control
Abstract

A 'test and treat' strategy is advocated for patients with dyspepsia under the age of 45 years, with endoscopy reserved for those with alarm symptoms or aged over 45 years. One of the consequences of this strategy will be a reduction in population infection rates of Helicobacter pylori. It is now clear that H. pylori is one of the prime initiators of gastric cancer with up to 70% of gastric cancers attributable to H. pylori. What remains unclear is if H. pylori reduction will lead to a reduction in gastric cancer.

Published
2003
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