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Your search keyword '"Liang, Yuelong"' showing total 190 results
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190 results on '"Liang, Yuelong"'

7. An ingestible, battery-free, tissue-adhering robotic interface for non-invasive and chronic electrostimulation of the gut.

Author

Nan, Kewang, Wong, Kiwan, Li, Dengfeng, Ying, Binbin, McRae, James C., Feig, Vivian R., Wang, Shubing, Du, Ningjie, Liang, Yuelong, Mao, Qijiang, Zhou, Enjie, Chen, Yonglin, Sang, Lei, Yao, Kuanming, Zhou, Jingkun, Li, Jian, Jenkins, Joshua, Ishida, Keiko, Kuosmanen, Johannes, and Mohammed Madani, Wiam Abdalla

Subjects
ELECTRONIC equipment, ELECTRIC stimulation, COUPLINGS (Gearing), GHRELIN, CLINICAL medicine
Abstract

Ingestible electronics have the capacity to transform our ability to effectively diagnose and potentially treat a broad set of conditions. Current applications could be significantly enhanced by addressing poor electrode-tissue contact, lack of navigation, short dwell time, and limited battery life. Here we report the development of an ingestible, battery-free, and tissue-adhering robotic interface (IngRI) for non-invasive and chronic electrostimulation of the gut, which addresses challenges associated with contact, navigation, retention, and powering (C-N-R-P) faced by existing ingestibles. We show that near-field inductive coupling operating near 13.56 MHz was sufficient to power and modulate the IngRI to deliver therapeutically relevant electrostimulation, which can be further enhanced by a bio-inspired, hydrogel-enabled adhesive interface. In swine models, we demonstrated the electrical interaction of IngRI with the gastric mucosa by recording conductive signaling from the subcutaneous space. We further observed changes in plasma ghrelin levels, the "hunger hormone," while IngRI was activated in vivo, demonstrating its clinical potential in regulating appetite and treating other endocrine conditions. The results of this study suggest that concepts inspired by soft and wireless skin-interfacing electronic devices can be applied to ingestible electronics with potential clinical applications for evaluating and treating gastrointestinal conditions. Existing ingestible electronics suffer from poor tissue contact, short dwell time, and limited battery life. Here, the authors report an ingestible, battery- free, and tissue-adhering robotic interface for non-invasive and chronic electrostimulation of the gut. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Global Trends in Research of Antimicrobial Peptides for the Treatment of Drug-Resistant Bacteria from 1995 to 2021: A Bibliometric Analysis

Author

Liang,Yuelong, Huang,Zhengze, Shen,Xuqiu, Zhang,Yiyin, Chai,Yihan, Jiang,Kexin, Chen,Qi, Zhao,Feng, Liang,Yuelong, Huang,Zhengze, Shen,Xuqiu, Zhang,Yiyin, Chai,Yihan, Jiang,Kexin, Chen,Qi, and Zhao,Feng

Abstract

Yuelong Liang,1,* Zhengze Huang,1,* Xuqiu Shen,1,* Yiyin Zhang,1 Yihan Chai,1 Kexin Jiang,1 Qi Chen,2 Feng Zhao3 1Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People’s Republic of China; 2Department of General Surgery, Hangzhou Fuyang Hospital of Traditional Chinese Medicine, Hangzhou, Zhejiang, People’s Republic of China; 3Department of Clinical Laboratory, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yuelong Liang; Feng Zhao, Email yuelongliang@zju.edu.cn; fengzhao3901@zju.edu.cnBackground: Antimicrobial peptides (AMPs) can act on the bacterial cell membrane to play an antibacterial role in types of drug-resistant bacteria. Therefore, AMPs have attracted more and more attention in the treatment of drug-resistant bacteria.Methods: Bibliometric analysis was employed to sort out the development and trends in the research of AMPs in the treatment of drug-resistant bacteria and map the knowledge structure for scholars.Results: Since 2010, the publications and citations in this field have exploded, indicating a growing global interest in the field of AMPs for the treatment of drug-resistant bacteria. And as major countries in this field, China and the USA had conducted very in-depth exchanges and cooperation, which had injected a steady stream of impetus into this field. Both old and new scholars have made efforts, and related fields have developed rapidly, especially in the synthesis and improvement of novel AMPs. In recent years, research directions in the field of AMPs for the treatment of drug-resistant bacteria gradually focused on the practical application, optimization of drug delivery mode, optimization of synthesis mode, screening of new AMPs and other fields, indicating that the relevant research results of AMPs for the

Published
2023

26. Cancer and COVID-19 Susceptibility and Severity: A Two-Sample Mendelian Randomization and Bioinformatic Analysis

Author

Zhang, Yiyin, primary, Mao, Qijiang, additional, Li, Yirun, additional, Cheng, Jiaxi, additional, Xia, Qiming, additional, Chen, Guoqiao, additional, Chen, Peng, additional, Jin, Shengxi, additional, Li, Duguang, additional, Zhong, Cheng, additional, Yang, Jing, additional, Fan, Xiaoxiao, additional, Liang, Yuelong, additional, and Lin, Hui, additional

Published
2022
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29. Clinically Available Optical Imaging Technologies in Endoscopic Lesion Detection: Current Status and Future Perspective

Author

He, Zhongyu, Wang, Peng, Liang, Yuelong, Fu, Zuoming, and Ye, Xuesong

Subjects
Article Subject
Abstract

Endoscopic optical imaging technologies for the detection and evaluation of dysplasia and early cancer have made great strides in recent decades. With the capacity of in vivo early detection of subtle lesions, they allow modern endoscopists to provide accurate and effective optical diagnosis in real time. This review mainly analyzes the current status of clinically available endoscopic optical imaging techniques, with emphasis on the latest updates of existing techniques. We summarize current coverage of these technologies in major hospital departments such as gastroenterology, urology, gynecology, otolaryngology, pneumology, and laparoscopic surgery. In order to promote a broader understanding, we further cover the underlying principles of these technologies and analyze their performance. Moreover, we provide a brief overview of future perspectives in related technologies, such as computer-assisted diagnosis (CAD) algorithms dealing with exploring endoscopic video data. We believe all these efforts will benefit the healthcare of the community, help endoscopists improve the accuracy of diagnosis, and relieve patients’ suffering.

Published
2021
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35. A tumor-suppressive circular RNA mediates uncanonical integrin degradation by the proteasome in liver cancer

Author

Shi, Liang, primary, Liu, Boqiang, additional, Shen, Dan-dan, additional, Yan, Peijian, additional, Zhang, Yanan, additional, Tian, Yuanshi, additional, Hou, Lidan, additional, Jiang, Guangyi, additional, Zhu, Yinxin, additional, Liang, Yuelong, additional, Liang, Xiao, additional, Shen, Bo, additional, Yu, Hong, additional, Zhang, Yan, additional, Wang, Yifan, additional, Guo, Xing, additional, and Cai, Xiujun, additional

Published
2021
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43. Experimental study of colonic anastomosis with a degradable stent in a porcine model

Author

Wang, YiFan, Cai, XiuJun, Cai, HuanJie, Liang, YueLong, Huang, DiYu, and Liang, Xiao

Subjects
Stent (Surgery), Health
Abstract

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.amjsurg.2009.05.044 Byline: YiFan Wang, XiuJun Cai, HuanJie Cai, YueLong Liang, DiYu Huang, Xiao Liang Keywords: Colonic anastomosis; Degradable stent; Colonic surgery; Intestinal anastomosis Abstract: Intestinal anastomosis is a major technical component of gastrointestinal procedures. We have developed a new procedure of colonic anastomosis with a degradable stent. This article evaluates this procedure. Author Affiliation: Department of General Surgery, Sir Run Run Shaw Hospital, College of Medicine, The Institute of Minimally Invasive Surgery, Zhejiang University, No 3, East Qinchun Rd., Hangzhou, People's Republic of China 310016 Article History: Received 27 February 2009; Revised 29 April 2009 Article Note: (footnote) Supported by the Hi-tech Research and Development Program of China (863 Program; No2007AA02Z446); and the Major Program of Science and Technology Department of Zhejiang Province (No. 2006C23090).

Published
2010

45. Enhanced recovery care versus traditional care after laparoscopic liver resections: a randomized controlled trial

Author

Liang, Xiao, primary, Ying, Hanning, additional, Wang, Hongwei, additional, Xu, Hongxia, additional, Liu, Minjun, additional, Zhou, Haiyan, additional, Ge, Huiqing, additional, Jiang, Wenbin, additional, Feng, Lijun, additional, Liu, Hui, additional, Zhang, Yingchun, additional, Mao, Zhiying, additional, Li, Jianhua, additional, Shen, Bo, additional, Liang, Yuelong, additional, and Cai, Xiujun, additional

Published
2017
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46. Liver cirrhosis grading Child-Pugh class B: a Goliath to challenge in laparoscopic liver resection?—prior experience and matched comparisons

Author

Cai, Xiujun, Liang, Xiao, Yu, Tunan, Liang, Yuelong, Jing, Renan, Jiang, Wenbing, Li, Jianbo, and Ying, Hanning

Subjects
Original Article
Abstract

Laparoscopic hepatectomy (LH) is highly difficult in the background of liver cirrhosis. In this case series, we aimed to summarize our prior experience of LH in liver cirrhosis grading Child-Pugh class B.In the LH database of Sir Run Run Shaw Hospital in Zhejiang, China, patients who were pathologically diagnosed with cirrhosis and graded as Child-Pugh class B or C were reviewed.Five patients grading Child B were included. There was no Child C case in our LH database. For included cases, median blood loss (BL) was 800 (range, 240-1,000) mL, median operative time was 135 (range, 80-170) minutes, and median length of hospital stay was 9 (range, 7-15) days. Forty percent (2/5) of patients was converted to open. The postoperative complication (PC) rate was 20.0% (1/5). When these Child B cases were compared with Child A cases undergoing LH, there was no statistical significance in BL, complication rate, operative time, open rate and hospital stay (HS) (P0.05). This finding was confirmed by two ways of matched comparisons (a 1:2 comparison based on age and gender, and a 1:1 propensity score matching).Although relevant literatures had suggested feasibility of LH in cirrhotic cases grading Child A, this study was the first one to discuss the value of LH in Child B cases. Our prior experience showed that in selected patients, LH in Child B patients had the potential to be as safe as in Child A cases. The efficacy of LH in Child C patients needs further exploration.

Published
2015

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