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Your search keyword '"Lever, A.F."' showing total 167 results
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167 results on '"Lever, A.F."'

1. Body concentration of caesium-137 in patients from Western Isles of Scotland

Author

Isles, C.G., Robertson, I., Macleod, J.A.J., Preston, T., East, B.W., Hole, D.J., and Lever, A.F.

Subjects
Measurement, Radioisotopes -- Measurement, Radioactive pollution -- Scotland -- Measurement, Isotopes -- Measurement, Cesium -- Measurement
Abstract

Introduction Whole body concentrations of caesium-137 are closely related to dietary intake of the isotope, [1] which has a physical half life of 30 years but a biological half life [...]

Published
1991

2. Incidence of and mortality from cancer in hypertensive patients

Author

Hole, D.J., Hawthorne, V.M., Isles, C.G., McGhee, Sarah M., Robertson, J.W.K., Gillis, C.R., Wapshaw, Jean A., and Lever, A.F.

Subjects
Risk factors, Health aspects, Cancer -- Risk factors, Atenolol -- Health aspects
Abstract

Objectives--To assess incidence of and mortality from cancer in hypertensive patients taking atenolol, comparing the findings with two control populations and with hypertensive patients taking other drugs. Design--Retrospective analysis of [...]

Published
1993

4. INTER-RELATIONSHIPS BETWEEN PLASMA ANGIOTENSIN II, ARTERIAL PRESSURE, ALDOSTERONE AND EXCHANGEABLE SODIUM IN NORMOTENSIVE AND HYPERTENSIVE MAN

Author

BEEVERS, D.G., primary, BROWN, J.J., additional, CUESTA, V., additional, DAVIES, D.L., additional, FRASER, R., additional, LEBEL, M., additional, LEVER, A.F., additional, MORTON, J.J., additional, OELKERS, W., additional, ROBERTSON, J.I.S., additional, SCHALEKAMP, M.A., additional, and TREE, M., additional

Published
1976
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5. Specific Inhibitors of Renin

Author

Szelke, M., primary, Hallett, A., additional, Jones, D.M., additional, Sueiras, J., additional, Atrash, B., additional, Leckie, B., additional, Tree, M., additional, and Lever, A.F., additional

Published
1983
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10. Sodium and potassium in essential hypertension.

Author

Lever, A.F., Beretta-Piccoli, C., Brown, J.J., Davies, D.L., Fraser, R., and Robertson, J.I.S.

Subjects
*ELECTROLYTES, *HYPERTENSION, *PATIENTS, *PRECANCEROUS conditions
Abstract

Examines the arterial pressure and body content of electrolytes in patients with essential hypertension. Enumeration of hypotheses proposed to explain the mechanisms related to electrolytes and arterial pressure; Development of renal lesions as a consequence of the hypertension; Characterization of the lesions.

Published
1981
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11. CORRESPONDENCE.

Author

Robinson, Jean, Murphy, Elaine, Misra, S.P., Dwivedi, M., Worrell, John, Midgley, A.K., Galea, M.H., Price, J.S., Shaper, A.G., Phillips, A.N., Pocock, S.J., Joffe, Michael, Isles, C.G., Hole, D.J., Gillis, C.R., Hawthorne, V.M., Lever, A.F., and Streetly, Alison

Subjects
MEDICAL research, ULTRASONIC imaging, CYCLING
Abstract

Presents several correspondence on medical research. Improvement on the investigation of complaints; Importance of ultrasonography on the patency of the cystic ducts; Hazards of long distance cycling.

Published
1989

14. Enalapril in the treatment of hypertension with renal artery stenosis.

Author

Hodsman, G.P., Brown, J.J., Cumming, A.M.M., Davies, D.L., East, B.W., Lever, A.F., Morton, J.J., Murray, G.D., Robertson, I., and Robertson, J.I.S.

Subjects
THERAPEUTICS, HYPERTENSION, RENAL artery, RENIN, CHEMICAL inhibitors
Abstract

Examines the inhibition of enalapril in the treatment of hypertension with renal artery stenosis. Relation of blood pressure to the pretreatment plasma concentrations of active renin and angiotensin II; Rise in active renin during long term treatment; Reduction in exchangeable sodium by enalapril.

Published
1983
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15. CORRESPONDENCE.

Author

Niswander, Kenneth R., Grant, Adrian, O'Brien, Niall, Whalley, L.J., Campbell, W. David, Wren, D.R., Corder, Allan, Atkinson, A.B., Cumming, Alison M.M., Lever, A.F., Morton, J.J., Brown, J.J., Fraser, R., Leckie, Brenda, Robertson, J.I.S., Thiery, Michel, Goethals, Anita, and Philip, Alistair G.S.

Subjects
MEDICINE, GENETICS of Alzheimer's disease, RESPIRATORY distress syndrome
Abstract

Presents several letters concerning medicine. Genetic aspects of Alzheimer's disease; Advances in respiratory distress syndrome; Ethical issues in in-vitro fertilization; Pharmacological treatment for intractable sneezing.

Published
1982

16. Captopril in renovascular hypertension: long-term use in predicting surgical outcome.

Author

Atkinson, A.B., Brown, J.J., Cumming, A.M.M., Fraser, R., Lever, A.F., Leckie, B.J., Morton, J.J., and Robertson, J.I.S.

Subjects
CAPTOPRIL, RENOVASCULAR hypertension, DRUG efficacy, THERAPEUTICS
Abstract

Examines the effectiveness of captopril for the treatment of renovascular hypertension. Decrease of plasma angiotensin II and aldosterone concentrations; Increase in circulation of renin and angiotensin I; Function of renin-angiotensin system in the pathogenesis of revovascular hypertension.

Published
1982
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17. Hypokalaemia in Alcoholics

Author

Dominiczak, A.F., Semple, P.F., Fraser, R., Lever, A.F., and Wallace, A.M.

Abstract

Hyponatraemia has been described in beer drinkers and hypokalaemia resulting from increased levels of aldosterone is well recognised in patients with cirrhosis and ascites. We have encountered episodes of hypokalaemia in alcoholics accompanied by normal or increased serum concentrations of sodium. Despite a resemblance to syndromes of mineralocorticoid excess, increased levels of aldosterone and other mineralocorticoids were not found.

Published
1989
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18. HYPONATRÆMIC HYPERTENSIVE SYNDROME WITH RENAL-ARTERY OCCLUSION CORRECTED BY CAPTOPRIL

Author

Atkinson, A.B., Davies, D.L., Leckie, B., Morton, J.J., Brown, J.J., Fraser, R., Lever, A.F., and Robertson, J.I.S.

Abstract

Malignant hypertension with severe hyponatræmia, hypokalæmia, depletion of sodium and potassium, and elevated blood levels of renin, angiotensin I, angiotensin II, aldosterone, and arginine vasopressin developed in a woman with renal-artery occlusion. Plasma angiotensin II was disproportionately high in relation to exchangeable sodium. Captopril, by inhibiting conversion of angiotensin I to angiotensin II, further elevated the blood levels of renin and angiotensin I but corrected all other abnormalities. Unilateral nephrectomy was subsequently curative.

Published
1979
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21. Enalapril in Treatment of Hypertension with Renal Artery Stenosis

Author

Hodsman, G.P., Brown, J.J., Cumming, A.M.M., Davies, D.L., East, B.W., Lever, A.F., Morton, J.J., Murray, G.D., and Robertson, J.I.S.

Abstract

The converting enzyme inhibitor enalapril, in single daily doses of 10 to 40 mg, was given to 20 hypertensive patients with renal artery stenosis. The decrease in blood pressure six hours after the first dose of enalapril was significantly related to the pretreatment plasma concentrations of active renin and angiotensin II, and to the concurrent decrease in angiotensin II. Blood pressure decreased further with continued treatment; the long-term decrease was not significantly related to pretreatment plasma renin or angiotensin II levels. At three months, 24 hours after the last dose of enalapril, blood pressure, plasma angiotensin II, and converting enzyme activity remained low, and active renin and angiotensin I high; six hours after dosing, angiotensin II had, however, decreased further. The increase in active renin during long-term treatment was proportionately greater than the increase in angiotensin I; this probably reflects the diminution in renin substrate that occurs with converting enzyme inhibition. Long-term enalapril treatment increased renin secretion by more than 10-fold, and renal venous and peripheral plasma renin concentration by more than 20-fold; however, the mean renal venous renin ratio was not changed. Enalapril caused a reduction in effective renal plasma flow via the affected kidney but a marked and consistent increase on the contralateral side, where renal vascular resistance decreased. The overall increase in effective renal plasma flow was significantly related to the decrease in angiotensin II. Overall glomerular filtration rate was lowered, and serum. creatinine and urea increased. Enalapril alone caused a longterm reduction in exchangeable sodium, with slight but distinct increases in serum potassium. In five patients with bilateral renal artery lesions, enalapril given alone for three months did not cause renal function to deteriorate. Enalapril was well tolerated and provided effective long-term control of hypertension; only two of the 20 patients studied required concomitant diuretic treatment.

Published
1984
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22. Malignant hypertension in women of childbearing age and its relation to the contraceptive pill.

Author

Lim, K.G., Isles, C.G., Hodsman, G.P., Lever, A.F., and Robertson, J.W.K.

Subjects
ORAL contraceptives, HYPERTENSION
Abstract

Examines the occurrence of malignant phase hypertension as a complication of the contraceptive pill in Glasgow, Scotland. Measurement of the blood pressure of women taking contraceptives; Analysis of the renal failures among users and non-users of the pill; Prognosis of non-users.

Published
1987
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23. Reconstructive surgery versus nephrectomy in renal artery stenosis: comparison of effects on total and divided renal function and on blood pressure.

Author

Mackay, A., Brown, J.J., Lever, A.F., and Robertson, J.I.S.

Subjects
PLASTIC surgery, RENAL artery
Abstract

Examines the effects of reconstructive surgery and nephrectomy on patient with renal artery disease. Comparison between the effect of the two techniques; Impact of the surgery on the renal function and blood pressure; Methodology of surgical management on patient.

Published
1980
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24. Excess smoking in malignant-phase hypertension.

Author

Isles, C., Brown, J.J., Cumming, A.M.M., Lever, A.F., McAreavey, D., Robertson, J.I.S., Hawthrone, V.M., Stewart, G.M., Robertson, J.W.K., and Wapshaw, J.

Subjects
SMOKING, HYPERTENSION
Abstract

Compares the smoking habits of patients with malignant-phase and non-malignant hypertension in Great Britain. Significance on excess of smokers; Proportions of smokers in each group; Occurrence of renal failure in malignant-phase hypertension patients.

Published
1979
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25. Converting-enzyme inhibitor enalapril (MK421) in treatment of hypertension with renal artery stenosis.

Author

Hodsman, G.P., Brown, J.J., Davies, D.L., Fraser, R., Lever, A.F., Morton, J.J., Murray, G.D., and Robertson, J.I.S.

Subjects
ENZYME inhibitors, HYPERTENSION, ARTERIAL stenosis
Abstract

Examines the converting-enzyme inhibitor enalapril for the treatment of hypertension with renal artery stenosis. Indication of good blood-pressure control during the long term treatment of enalapril maleate; Absence of changes of body sodium and potassium values; Efficacy and acceptability of enalapril in the medical management of hypertension.

Published
1982
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32. INACTIVE RENIN IN HUMAN PLASMA

Author

Leckie, B., primary, Brown, J.J., additional, Lever, A.F., additional, Mcconnell, A., additional, Morton, J.J., additional, Robertson, J.I.S., additional, and Tree, M., additional

Published
1976
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34. CAPTOPRIL OR FRUSEMIDE IN DRUG-RESISTANT HYPERTENSION?

Author

Kristensen, BentØ., primary, Skov, Jesper, additional, Atkinson, A.B., additional, Brown, J.J., additional, Lever, A.F., additional, Robertson, J.I.S., additional, White, N.J., additional, Rajagopalan, B., additional, Yahaya, H., additional, and Ledingeam, J.G.G., additional

Published
1980
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36. LABETALOL IN HYPERTENSION

Author

Brown, J.J., primary, Lever, A.F., additional, Cumming, A.M.M., additional, Robertson, J.I.S., additional, Richards, D.A., additional, Harris, D.M., additional, and Jack, D., additional

Published
1977
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37. SALT AND HYPERTENSION

Author

Brown, J.J., primary, Lever, A.F., additional, Robertson, J.I.S., additional, Semple, P.F., additional, Bing, R.F., additional, Heagerty, A.M., additional, Swales, J.D., additional, Thurston, H., additional, Ledingham, J.G.G., additional, Laragh, J.H., additional, Hansson, L., additional, Nicholls, M.G., additional, and Espiner, E.A., additional

Published
1984
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47. Measurements of 137Caesium Levels in Residents of Western Scotland

Author

Isles, C.G., primary, Robertson, I., additional, Brown, J.J., additional, Cumming, A.M.M., additional, East, B.W., additional, Gault, J., additional, Harvey, I., additional, Lever, A.F., additional, McLeod, J., additional, Preston, T., additional, Robertson, J.I.S., additional, and Semple, P.F., additional

Published
1983
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48. The adrenal cortex and hypertension: Some observations on a possible role for mineralocorticoids other than aldosterone

Author

Fraser, R., primary, Brown, J.J., additional, Brown, W.C., additional, Ferriss, J.B., additional, Kennedy, A., additional, Lever, A.F., additional, Mason, P.A., additional, Morton, J.J., additional, Nicholls, M.G., additional, Ramsay, L.E., additional, Robertson, J.I.S., additional, Schalekamp, M.A.D., additional, and Wilson, A., additional

Published
1976
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