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Super-refractory status epilepticus (SRSE) represents a neurological emergency that is characterized by a lack of response to the third line of antiepileptic treatment, including intravenous general anesthetics. It is a medical challenge with high morbidity and mortality. Electroconvulsive therapy (ECT) has been recommended as a nonpharmacologic option of treatment after other alternatives are unsuccessful. Its effect on the cessation of SRSE has been minimally investigated. The objective of this article is to analyze the effect of ECT on SRSE. For this purpose, a multidisciplinary team created a protocol based on clinical guidelines similar to those described previously by Ray et al. (2017). ECT was applied to six patients with SRSE after the failure of antiepileptic treatment and pharmacologic coma.The objective of each ECT session was to elicit a motor seizure for at least 20 s. SRSE was resolved in all patients after several days of treatment, including ECT as a therapy, without relevant adverse effects. Thus, ECT is an effective and feasible option in the treatment of SRSE, and its place in the algorithm in treatment should be studied due to the uncommon adverse effects and the noninvasive character of the therapy.

The relationship between multiple sclerosis (MS) and females is a crucial aspect in the development of the disease, with the ovarian hormonal cycle being a sensitive stage, especially in females with relapsing-remitting multiple sclerosis. The objectives of the study are to identify moderating variables that modify satisfaction with physical activity practice throughout the menstrual cycle (MC) in females in or out of their MC, during high-intensity interval training (HIIT) and strength training sessions and to compare the acute effects of different types of physical activity sessions in females with and without MS. This protocol is the methodology used in the EMMA Study, a randomised, single-blind crossover trial study conducted in females with MS who were matched 1:1, based on age, lifestyle factors and country of residence, with females without MS, to analyse the effect of physical activity practice on satisfaction, functionality, fatigue and inflammatory profile through their MC. Participants will visit the facilities approximately 10 times (4 preliminary familiarisation visits and 6 visits to carry out a physical activity session in each phase of the MC) for 3–4 months. A total sample of 30 females (15 females without MS and 15 with MS) is necessary for the study. The evaluation will comprise clinical, nutritional and psychological interviews, including different variables. It is hypothesised during the luteal phase, females with MS are expected to exhibit different acute responses to HIIT and strength training sessions as compared with females without the disease. Before starting the study, all participants will read and sign an informed consent form. Trial registration number: This research protocol is registered with ClinicalTrials.gov to ensure transparency and accessibility of study information (NCT06105463). The university’s ethics committee number for this study is UALBIO2022/048.

Aim: to describe the perception of 201 nurses, regarding patient safety in their centers, to determine the strengths and areas of improvement in Health District of Almería. Methodology: The Medical O ce Survey on Patient Safety Culture questionnaire (MOSPSC) was used translated, adapted and assessed for Spanish primary healthcare pro esionals in Primary Care. Using the statistic program SPSS was calculated the mean and 95% con dence interval of each of the questionnaire dimensions. Results: A positive perception was found in the SP for almost all of the questionnaire dimensions, with the exception of “error communication”, “patient care follow-up”, “clear communication” and “work load and work rhythm”. One of the strengths of the nurses is “team work”. Conclusions: the results have also highlighted the “information exchange with other healthcare departments”; on the other hand, among those areas to be improved we nd “clear communication and error communication”. The results of these questionnaires may assist in evaluating the importance of patient safety in the organizations, in order to create dialogue on the errors and create a climate of learning and a desire to improve in healthcare professionals, with positive repercussions on the quality of care o ered to users., Objetivo: describir la percepción que tienen 201 enfermeros en relación a la Seguridad del Paciente (SP) en sus centros, valorar cuáles son los puntos fuertes y las áreas de mejora en los Distritos Sanitarios de la provincia de Almería. Metodología: Se ha utilizado el cuestionario denominado MOSPSC (Medical Office Survey on Patient Safety Culture), traducido, adaptado y validado para profesionales españoles de Atención Primaria. A través del programa estadístico SPSS, se calculó la media y el intervalo de confianza al 95% de cada una de las dimensiones del cuestionario. Resultados: se observa una percepción positiva de la SP en casi todas las dimensiones, a excepción de la “Comunicación sobre el error”, el “Seguimiento de la atención a los pacientes”, la “Comunicación franca” y el “Ritmo y Carga de trabajo”. Uno de los puntos fuertes de los enfermeros es el “trabajo en equipo”. Conclusiones: Los resultados de esta investigación también han destacado “el intercambio de información con otros equipos”; en cambio, entre las áreas de mejora que deberían tenerse en cuenta se halla, “la Comunicación franca y sobre el error”. Estos resultados deberían ayudar a evaluar la importancia de la SP en las organizaciones, para dialogar sobre los errores y crear un clima de aprendizaje y deseo de mejora en los profesionales que repercuta en la calidad de la atención ofrecida a los usuarios.