1. To determine the significance and role of hematological parameters among type 2 diabetes mellitus-comparative cross sectional study.
- Author
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Kishore, Jugnu, Kumar, Pramit, Sinha, Navin Kumar, and Kumar, Uday
- Subjects
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MEAN platelet volume , *TYPE 2 diabetes , *NEUTROPHIL lymphocyte ratio , *GLYCEMIC control , *PLATELET count , *LYMPHOCYTE count - Abstract
Background: Hematological parameters such as hemoglobin, white blood count (WBC), Mean Platelet volume, hematocrit (HCT), MCV, MCH, MCHC, RBC counts, neutrophil to lymphocyte ratio (NLR), and platelet/lymphocyte ratio (PLR) play significant role in progression of Diabetes mellitus. Aims: Purpose of this study is to evaluate hematological parameters in diabetic patients and compare it with the non diabetic healthy controls. Materials and Methods: One hundred twenty patients with type 2 diabetes mellitus and similar number of age matched healthy individuals served as the control group. Hematological parameters such as hemoglobin, mean platelet volume (MPV), glycosylated haemoglobin (HbA1c), hematocrit (Hct), neutrophil and lymphocyte count, NLR, platelets, platelet/lymphocyte ratio (PLR), and LMR were analysed in both the groups and compared. Results: One hundred twenty diabetic patients and same number of age matched healthy controls were enrolled. Majority of the cases (25%) and controls (26.3%) were 41-50 years age group, predominantly male 56.3% cases and 55% were control. BMI was significantly higher among diabetic cases as compared to control. Among hematological parameters: hemoglobin, RBCs count, MCV, MCH, MCHC and HCT were significantly lower whereas RDW, were significantly higher among diabetic patients as compared to control. WBC count, lymphocytes, neutrophils counts and NLR were significantly higher in the diabetic patients, however, no significant differences were observed in platelet counts between patients and controls Conclusions: Hematologic parameters were significantly altered in diabetes mellitus patients can be utilized as cost-effective predictors of diabetic microvascular complications [ABSTRACT FROM AUTHOR]
- Published
- 2024