25 results on '"Koray Erten"'
Search Results
2. Association between Gene Polymorphism of Manganese Superoxide Dismutase and Prostate Cancer Risk
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Ahmet Aydin, Ljubica Suturkova, Onur Erdem, Koray Erten, Ahmet Sayal, Aleksandar Dimovski, Yasar Ozgok, Cemal Akay, Nadica Matevska, Ayşe Eken, and Zorica Arsova-Sarafinovska
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chemistry.chemical_classification ,Reactive oxygen species ,medicine.medical_specialty ,Antioxidant ,business.industry ,Health, Toxicology and Mutagenesis ,medicine.medical_treatment ,General Medicine ,Disease ,Mitochondrion ,Toxicology ,medicine.disease ,Biochemistry ,Prostate cancer ,Endocrinology ,chemistry ,Internal medicine ,Immunology ,Genotype ,medicine ,Molecular Medicine ,Gene polymorphism ,Allele ,business ,Molecular Biology - Abstract
Manganese superoxide dismutase (MnSOD) is the most effective antioxidant enzyme in mitochondria and protects cells from reactive oxygen species-induced oxidative damage. The aim of this study was to investigate the association between MnSOD Ala-9 Val gene polymorphism and prostate cancer (PCa) risk in Turkish men with prostate cancer. 33 patients with PCa and 81 control individuals were included in the study. We observed an association between MnSOD Ala/Ala frequency and a higher PCa risk. In addition, we found that the increased risk of early-onset PCa (under age of 65) in the men homozygous for Ala allele was higher than the men homozygous for Val allele. However, we determined that MnSOD Ala-9 Val genotype was not associated with the aggressiveness of the disease. The results of our study suggest that MnSOD Ala/Ala genotype may influence on early-onset of PCa patients, but no effect on subsequent development of the disease in Turkish men. However, our study has a limitation that is small numbers of individuals for cases and controls. Therefore, the presented study limited our statistical power to fully investigate the gene polymorphism on cancer risk.
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- 2013
3. Association ofGPX1polymorphism, GPX activity and prostate cancer risk
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Onur Erdem, Ahmet Aydin, Aleksandar Dimovski, Cemal Akay, Yasar Ozgok, Ayşe Eken, Zorica Arsova-Sarafinovska, Nadica Matevska, Ljubica Suturkova, Ahmet Sayal, and Koray Erten
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Male ,Turkish population ,GPX1 ,Erythrocytes ,Antioxidant ,Genotype ,Health, Toxicology and Mutagenesis ,medicine.medical_treatment ,Disease ,Biology ,Toxicology ,medicine.disease_cause ,Prostate cancer ,Glutathione Peroxidase GPX1 ,Gene Frequency ,Risk Factors ,medicine ,Humans ,Aged ,Glutathione Peroxidase ,Polymorphism, Genetic ,Prostatic Neoplasms ,General Medicine ,Middle Aged ,Prostate-Specific Antigen ,medicine.disease ,Case-Control Studies ,Immunology ,Cancer research ,Oxidative stress ,Biomedical sciences - Abstract
Prostate cancer is the second most common cancer in men worldwide. Although the aetiology of this disease remains largely unclear, several lines of evidence suggest that oxidative stress plays a role in prostate carcinogenesis. The antioxidant enzyme glutathione peroxidase 1 (GPX1) is part of the enzymatic antioxidant defence, preventing oxidative damage to DNA, proteins and lipids by detoxifying hydrogen and lipid peroxides that may contribute to prostate cancer development. Some studies indicate an association between GPX1 Pro198Leu polymorphism and an increased risk of cancer. The purpose of the present study was to determine the possible association of GPX1 Pro198Leu polymorphism and erythrocyte GPX activity with the risk of developing prostate cancer and to clarify whether erythrocyte GPX activity levels were correlated with the GPX1 Pro198Leu genotype in the Turkish population. The GPX1 Pro198Leu genotype was determined in 33 prostate cancer patients and 91 control individuals. As evident from our results, there was no difference between genotype and/or allele frequencies in prostate cancer patients and controls. No significant difference was found in GPX1 genotype or allele frequency between aggressive and non-aggressive prostate cancer patients. It can be suggested with these findings that individual susceptibility of prostate cancer may be modulated by GPX1 polymorphism, but it needs further studies.
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- 2011
4. Isolated relapse of a lymphoblastic leukemia T cell precursor in the epididymis
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Turgay Ebiloglu, Engin Kaya, Giray Ergin, İbrahim Yaşar Özgök, Emin Ozan Akay, Oral Nevruz, Koray Erten, and Mehmet Salih Deveci
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Pathology ,medicine.medical_specialty ,business.industry ,Urology ,Lymphoblastic Leukemia ,T cell ,medicine.disease ,Epididymis ,Sperm ,Asymptomatic ,Lymphoma ,Leukemia ,medicine.anatomical_structure ,hemic and lymphatic diseases ,Epididymectomy ,Medicine ,medicine.symptom ,business ,Urooncology - Abstract
A 41-year-old man who had otherwise asymptomatic right scrotal swelling presented to our urology clinic. He had been diagnosed with T cell precursor lymphoblastic leukemia/lymphoma 2 years previously. On examination, his right epididymis was enlarged. A regular, homogeneous, slightly hypoechoic solid mass was observed at the right caput epididymis. This testicular mass measured approximately 7×11×12 mm. Leukemia and lymphoma appear in a variety of locations throughout the body, but an isolated relapse involving the epididymis is rare. Epididymectomy was performed which naturally removed the patient's right-sided sperm duct system. Especially in the younger age group epididymal masses can lead to fertility problems.
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- 2014
5. Rapid and Simple Determination of Plasma and Erythrocyte MDA Levels in Prostate Cancer Patients by a Validated HPLC Method
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Ahmet Aydin, Yasar Ozgok, Ahmet Sayal, Koray Erten, Ayşe Eken, Zorica Arsova-Sarafinovska, Aleksandar Dimovski, Ayhan Savaser, and Onur Erdem
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medicine.medical_specialty ,Chromatography ,Clinical Biochemistry ,Urology ,Pharmaceutical Science ,Hyperplasia ,Malondialdehyde ,medicine.disease ,Biochemistry ,High-performance liquid chromatography ,Analytical Chemistry ,Lipid peroxidation ,Red blood cell ,chemistry.chemical_compound ,Prostate cancer ,medicine.anatomical_structure ,chemistry ,Blood plasma ,medicine ,skin and connective tissue diseases ,Quantitative analysis (chemistry) - Abstract
We undertook the present study to develop a validated HPLC method for the determination of malondialdehyde (MDA) levels and to use this method for determination of MDA levels in patients with prostate cancer and benign prostatic hyperplasia. MDA levels were estimated in the erythrocyte and plasma sample of the 25 non-metastatic prostate cancer patients, 36 benign prostatic hyperplasia (BPH) patients and 24 age- and sex-matched healthy subjects (controls) in HP Chromatographic systems consisting of a Model Agilent 1100 Series. We report a very rapid and simple isocratic reversed-phase HPLC separation of MDA in normal human plasma and erythrocytes without previous purification of the NMA-TBA complex. All validation parameters were performed in our methods. Using this methods we have found elevated MDA in the plasma and erythrocyte of the prostate cancer group as compared to controls and BPH group. We have improved and validated an analytical HPLC method for determination of MDA in plasma and erythrocyte, which is simple to perform and having high sensitivity, specificity and substantial improvement in column life. This method has been successfully applied to determination of MDA levels in prostate cancer patients and offers an oportunity to further characterize the role of oxidative injury in the pathogenesis of this disease specifically.
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- 2007
6. Comparing Two Local Anesthesia Techniques for Extracorporeal Shock Wave Lithotripsy
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Mete Kilciler, Yasar Ozgok, Selahattin Bedir, Koray Erten, Erkan Demir, and Çukurova Üniversitesi
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Adult ,Male ,medicine.medical_specialty ,Lidocaine ,medicine.drug_class ,Visual analogue scale ,Urology ,medicine.medical_treatment ,Lithotripsy ,Prilocaine ,medicine ,Humans ,Local anesthesia ,Prospective Studies ,Lidocaine, Prilocaine Drug Combination ,Aged ,Local anesthetic ,business.industry ,Muscle relaxant ,Middle Aged ,Extracorporeal shock wave lithotripsy ,Anesthetics, Combined ,Surgery ,Anesthesia ,Female ,business ,Anesthesia, Local ,medicine.drug - Abstract
Objectives To evaluate the efficacy of a eutectic mixture of local anesthetics (EMLA) cream compared with dimethyl sulfoxide (DMSO) with lidocaine during extracorporeal shock wave lithotripsy (ESWL) in a prospective randomized study. Methods Of 167 patients, 85 received 10 g of EMLA cream (EMLA group) and 82 received 10 g of 40% DMSO (DMSO group) with an amount of lidocaine equal to that in the lidocaine gel, applied to the skin of the flank at the area of entry of the shock wave marked by the urologist. A second-generation lithotriptor Siemens Lithostar was used. The degree of pain was rated by the patients using a 10-point visual analog scale. Results In 80 patients in the EMLA group (94%), the entire procedure was performed with no, minor, or tolerable pain after the application of EMLA cream (pain score 5.2 ± 1.3). In 5 EMLA patients (6%), EWSL was interrupted because of intolerable pain. Of the 82 DMSO patients, 80 (98%) underwent the entire procedure with no, minor, or tolerable pain after the application of DMSO with lidocaine (pain score 3.7 ± 1.1). In 2 DMSO patients (2%), EWSL was interrupted because of intolerable pain. The pain scores were significantly lower for the DMSO group than for the EMLA group ( P = 0.011). Conclusions Our findings have indicated that the pain scores were significantly lower for the DMSO group than for the EMLA group. In addition to the local anesthetic effect of DMSO, diuretic, anti-inflammatory, muscle relaxant, and hydroxyl radical scavenger effects can be important for patients undergoing ESWL. These effects should be evaluated with new studies of patients undergoing ESWL.
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- 2007
7. Clinical Significance of Platelet Count in Patients with Renal Cell Carcinoma
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Yasar Ozgok, Hidayet Coban, Mete Kilciler, Selahattin Bedir, Koray Erten, and Fikret Erdemir
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Adult ,Male ,Pathology ,medicine.medical_specialty ,Urology ,medicine.medical_treatment ,urologic and male genital diseases ,Nephrectomy ,Gastroenterology ,Renal cell carcinoma ,Internal medicine ,medicine ,Carcinoma ,Humans ,Platelet ,Clinical significance ,Carcinoma, Renal Cell ,Survival analysis ,Aged ,Retrospective Studies ,Thrombocytosis ,Platelet Count ,business.industry ,Retrospective cohort study ,Middle Aged ,Prognosis ,medicine.disease ,Survival Analysis ,Kidney Neoplasms ,female genital diseases and pregnancy complications ,Female ,business - Abstract
Introduction: During the last decades numerous prognostic factors have been studied for predicting survival of renal cell carcinoma (RCC). Platelet count has previously been reported to correlate with prognosis in RCC. The aim of the this study was to evaluate the significance of thrombocytosis in determining prognosis in patients with localized RCC who underwent radical nephrectomy. Patients and Methods: The study included 118 consecutive patients. Patients were divided into a normal platelet count group (group 1) and a thrombocytosis group (group 2) according to the preoperative platelet count. Thrombocytosis was defined as a platelet count greater than 400,000/µl. The data about stage distribution, grade, tumor size, histological subtype, hemoglobin level, Body Mass Index (BMI), age, ECOG score, gender, and survival rate of tumors between these two groups were compared. Survival estimates were compared with the Kaplan-Meier method and multivariate analysis was performed using a Cox model. Results: The mean age of the patients was 61.4 years (range 30–78), and the mean follow-up period was 52.7 ± 19.6 months (range 9–96). Thrombocytosis was present in 23 patients (19.49%). Fourteen (60.86%) of 23 patients with thrombocytosis died of disease progression. Patients with thrombocytosis had a worse prognosis than patients without thrombocytosis (p = 0.001). Thrombocytosis was noted in 8 (10.81%) of 74 patients with stage pT1-pT2 disease and in 15 (34.09%) of 44 patients with stage pT3-pT4 disease (p = 0.004). In univariate analysis, platelet count was correlated with T stage, hemoglobin level, lymph node positivity, ECOG score, and tumor size. Controlling for established prognostic indicators of pathologic stage, tumor size, platelet count, and lymph positivity using Cox’s regression test, the difference in survival between the groups remained significant (p < 0.05). Conclusion: The platelet count can be considered a useful prognostic factor in patients with RCC who undergo radical nephrectomy.
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- 2007
8. Spontaneous Ureteral Stent Fragmentation: A Case Report and Review of the Literature
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Oguz Guven, Hasret Topac, Mete Kilciler, Selahattin Bedir, Koray Erten, Fikret Erdemir, and Hidayet Coban
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Male ,Medicine(all) ,medicine.medical_specialty ,kidney ,lcsh:R5-920 ,Stone formation ,business.industry ,medicine.medical_treatment ,Stent ,General Medicine ,Ureteral stents ,Middle Aged ,Surgery ,fragmentation ,medicine ,Humans ,Stents ,Radiology ,Fragmentation (cell biology) ,business ,ureteral stent ,lcsh:Medicine (General) ,Ureteral Obstruction - Abstract
Ureteral stents have been widely used for more than two decades with different indications. Due to the widespread usage of ureteral stents, the number of possible complications of ureteral stents has increased, including stent migration, encrustation, stone formation, and fragmentation. Among these complications, ureteral stent fragmentation is rare. Herein, we present a case of spontaneous ureteral stent fragmentation and review the relevant literature.
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- 2006
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9. Oxidative stress and antioxidant status in non-metastatic prostate cancer and benign prostatic hyperplasia
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Aleksandar Dimovski, Ayşe Eken, Zorica Arsova-Sarafinovska, Koray Erten, Ahmet Sayal, Ahmet Aydin, Onur Erdem, and Yasar Ozgok
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Male ,medicine.medical_specialty ,Erythrocytes ,Clinical Biochemistry ,Prostatic Hyperplasia ,medicine.disease_cause ,Thiobarbituric Acid Reactive Substances ,Antioxidants ,Superoxide dismutase ,Lipid peroxidation ,Prostate cancer ,chemistry.chemical_compound ,Internal medicine ,medicine ,TBARS ,Humans ,Aged ,Aged, 80 and over ,chemistry.chemical_classification ,Glutathione Peroxidase ,biology ,Superoxide Dismutase ,Chemistry ,Glutathione peroxidase ,Health sciences ,Prostatic Neoplasms ,Cancer ,General Medicine ,Middle Aged ,Hyperplasia ,Catalase ,medicine.disease ,Biological sciences ,Oxidative Stress ,Zinc ,Endocrinology ,Clinical medicine ,biology.protein ,Lipid Peroxidation ,Copper ,Oxidative stress - Abstract
Objectives: We undertook the present study to investigate the possible alteration of oxidant/antioxidant status in the circulation of patients with prostate cancer and benign prostatic hyperplasia. Design and methods: Thiobarbituric acid reactive substances (TBARS), the enzyme activities of superoxide dismutase (SOD), glutathione peroxidase (GPX), catalase (CAT) and copper (Cu) and zinc (Zn) levels were estimated in the erythrocytes of 25 non-metastatic prostate cancer patients, 36 benign prostatic hyperplasia (BPH) patients and 24 age- and sex-matched healthy subjects (controls). Results: TBARS concentrations were significantly increased, while erythrocyte GPX and SOD activities were significantly decreased in the prostate cancer group versus controls (P < 0.001) and BPH group (P < 0.05). Zn levels were lowered in prostate cancer patients versus controls (P < 0.01) with no significant changes between BPH and cancer groups. Similarly, lipid peroxidation was increased (P < 0.05) with decreased SOD activity and Zn level (P < 0.05) in BPH versus controls. Conclusion: These results reveal an alteration in the lipid peroxidation index, with concomitant changes in the antioxidant defense system in prostate cancer patients compared to BPH patients. We hypothesize that an altered prooxidant–antioxidant balance may lead to an increase in oxidative damage and consequently may play an important role in prostate carcinogenesis. Keywords: Prostate cancer; Oxidative stress; Lipid peroxidation; Antioxidant enzymes
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- 2006
10. Condylomata acuminata of external urethral meatus causing infravesical obstruction
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Mete Kilciler, Fikret Erdemir, Hidayet Coban, Yasar Ozgok, Selahattin Bedir, Koray Erten, and Onder Ors
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Adult ,Male ,medicine.medical_specialty ,Urethral Obstruction ,medicine.diagnostic_test ,business.industry ,Urinary retention ,Urology ,Physical examination ,Alphapapillomavirus ,Condyloma Acuminatum ,Surgery ,Lesion ,medicine.anatomical_structure ,Urethra ,Condylomata Acuminata ,Nephrology ,Frenulum ,medicine ,Humans ,medicine.symptom ,Radical Local Excision ,Glans ,business - Abstract
Condyloma acuminata is one of the most common virally transmitted diseases. The most common sites for condyloma in males are the balanopreputial sulcus, frenulum and the glans' mucosa. Condylomata in the urethra is rarely seen occur and most often situated in the distal part of the urethra. A 24-year-male admitted to our clinic with complaint of papillary lesion at the urethral meatus and urinary retention. Physical examination revealed that multiple papillary lesions along the anterior urethra until 1 cm distance from the urethral meatus. Under the clinical diagnosis of condyloma acuminata, he was treated conservatively with radical local excision of the lesion and condyloma acuminatum was verified by histopathological examination. Four months after surgery, there has been no local or remote recurrence.
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- 2007
11. Contents Vol. 79, 2007
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Carmen Pérez Romero, María del Puerto López del Amo González, Hamed Jalaeian, Zahran Budair, D.T. Consigliere, Yi Jun Shen, Isao Hara, Erkan Demir, Atsushi Takenaka, A. Blandino, Selahattin Bedir, P. Monardo, Hüseyin Aydemir, Yao Zhu, Takashi Tominaga, Selami Albayrak, Masato Fujisawa, Francesca Vichi, Erik Kouba, Toshifumi Kurahashi, Vedat Köksal, Francis Vacherot, Héctor Pastor-Navarro, Hideaki Miyake, Omer F. Karakas, Julio Escribano-Martínez, María J. Donate-Moreno, Yutaka Matsuyama, Manuel Atienzar-Tobarra, Toshiyuki Un-no, Kimio Fujita, Ali Thwaini, Miguel Segura-Martín, Xu Dong Yao, A.L. Morton, Mehdi Salehipour, T. Tony Cai, Iqbal S. Shergill, Yasuo Ohashi, Makoto Fujime, G. Bellinghieri, P.A. McArdle, Riccardo Bartoletti, H.H. Lim, J. Slade Hubbard, Kerem Inanoglu, D. Santoro, Selcuk Sahin, Bo Dai, Luca Cindolo, Volkan Tugcu, Francisco Sánchez-Sánchez, Eric Wallen, Fatih Zorluoglu, Onder Canguven, Cemal Göktaş, Hai Liang Zhang, Koray Erten, A. Magistro, José M. Giménez-Bachs, Ibrahim Hernández-Millán, K.K. Bhomi, Seijiro Honma, Mete Kilciler, Abdolaziz Khezri, Shi Lin Zhang, Clara Bermúdez-Tamayo, Shunsuke Nobata, Antonio Costanzi, Umberto Farina, Nader Tanideh, Stéphane Terry, F. Ciolino, Ahmet Fuat Peker, Antonio S. Salinas-Sánchez, H.Y. Tiong, Z. Hotiana, Ahmet Namık Kiper, Mohsen Kroup, Valiallah Azizi, Ding Wei Ye, Raj S. Pruthi, Fumitaka Shimizu, C.J. Adams, Wen Zhang, Alexandre de la Taille, José Jesús Martín Martín, Gianluca Giubilei, Seiichiro Ozono, Ali Ihsan Tasci, B. Cagla Ozbakis Akkurt, R.J.T. Alexander, Yılmaz Ordekci, V. Savica, Cenk Kilic, Ahmad Monabbati, Monica Cantile, Juan G. Lorenzo-Romero, Sadık Görür, Manit Arya, B. Vissamsetti, Hiroshi Sudoko, Yasar Candan, and Shinsuke Hayami
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Traditional medicine ,business.industry ,Urology ,Medicine ,business - Published
- 2007
12. Pain Scores and Early Complications of Transrectal Ultrasonography-Guided Prostate Biopsy: Effect of Patient Position
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Cenk Kilic, Mete Kilciler, Ahmet Fuat Peker, Erkan Demir, Selahattin Bedir, and Koray Erten
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Male ,medicine.medical_specialty ,Time Factors ,Prostate biopsy ,Urology ,Posture ,Pain ,urologic and male genital diseases ,Risk Assessment ,Prostate cancer ,Reference Values ,medicine ,Humans ,Prospective Studies ,Ultrasound, High-Intensity Focused, Transrectal ,Aged ,Hematuria ,Pain Measurement ,Probability ,Ultrasonography ,Pain score ,medicine.diagnostic_test ,business.industry ,Biopsy, Needle ,Prostatic Neoplasms ,Middle Aged ,medicine.disease ,Lithotomy position ,Position (obstetrics) ,Transrectal ultrasonography ,Radiology ,business ,Follow-Up Studies - Abstract
Background: The aim of the study was to evaluate the pain scores and complications of transrectal ultrasonography (TRUS)-guided prostate biopsy and to compare lithotomy position (LP) versus left lateral decubitis position (LLDP). Methods: A total of 340 patients were referred for TRUS-guided biopsy. In group 1 (n = 170), biopsies were performed in LP (n = 170), and in group 2 (n = 170) biopsies were performed in LLDP (n = 170). In 68 patients, biopsies were repeated. We constituted two additional groups: in group 3 (n = 33) patients underwent biopsies in LP and LLDP, respectively, and in group 4 (n = 35) patients underwent biopsies in LLDP and LP, respectively. Pain score, infection rates, hematospermia, hematuria, rectal bleeding, and serious complications were compared between group 1 and group 2. Pain scores were compared between the four groups. Results: There were no differences between group 1 and group 2 for age, prostate volume, prostate-specific antigen level, biopsy time, hematuria, infection, hematospermia, and rectal bleeding. Pain scores were lower in group 2 than in group 1. Also, for LLDP, pain scores were lower in group 3 and group 4. Conclusion: The effect of position on pain scores in TRUS biopsy patients has not been previously described. Our study indicates that pain scale values are lower in LLDP than in LP.
- Published
- 2007
13. Contents Vol. 75, 2005
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Michael Alschibaja, F. Pinto, Wen-Chi Chen, Ömür Ataoğlu, Ayhan Verit, Jörg Massmann, Angelo Porreca, Ali Unsal, Giampaolo Delicato, Ming-Tsung Lai, Giulio Nicita, Destito A, Tahsin Turunc, Pierre Mongiat-Artus, John P. Gearhart, Muzaffer Eroğlu, Maria Cristina Paoletti, Aylin Kanli, Alessandro D'Addessi, N.S. Johal, Pranjal R Modi, Michele Marzocco, S.N. Jayasena, Francois Desgrandchamps, E. Crucitta, L. Apthorp, Fuu-Jen Tsai, Mete Kilciler, I.M. Tavolini, R.O. Plail, Chung-Hsiung Huang, S. Corvin, Hale Maral Kir, Mustafa Cengiz, Chih-Ming Lu, Eugenio Di Grazia, Rajiv Yadav, Anis Aribogan, Chao-I Wu, Marco Racioppi, Stéphane Milcent, Wolfgang Sturm, Meng-Chu Chung, Fikret Erdemir, Surendra B. Kolla, Dominic Frimberger, Yasar Ozgok, M. Zucchetti, C. Kouriefs, L. Managadze, Zaza Mezvrishvili, Roger Paul, Maria Teresa Filocamo, Oguz Acar, Gagan Gautam, Meltem Ozlen Dillioglugil, Rajiv Goel, D.M.R. Gunawardena, Markus A. Kuczyk, Ersin Çimentepe, V. De Marco, Koray Erten, Armin Funk, M. Derya Balbay, Sharad Dodia, Monish Aron, Jean Marc Duclos, Ercan Yeni, Ashok K. Hemal, Hasan Bakırtaş, Lei Wan, M. V. C. De Silva, Ying-Chin Ko, Donata Villari, Selahattin Bedir, Dario Nicolosi, Aristotelis G. Anastasiadis, Dogan Unal, Rudolf Hartung, F. Longo, Atilla Aridogan, J.T.N. Ariyasinghe, Pierre Teillac, Nazario Foschi, Mathias Wegner, Hsi-Chin Wu, Paul Meria, L. Marini, Hacı Kahya Ozdogan, P. Bassi, S.A.S. Gunawardena, Sule Akin, F. Dal Moro, E. Dattolo, Arnulf Stenzl, Narmada P. Gupta, Vincenzo Li Marzi, Onder Ors, Huey-Yi Chen, Ozdal Dillioglugil, Mehmet Doğan Gülkaç, and Hidayet Coban
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Traditional medicine ,business.industry ,Urology ,Medicine ,business - Published
- 2005
14. Association between gene polymorphism of manganese superoxide dismutase and prostate cancer risk
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Ayşe, Eken, Onur, Erdem, Zorica, Arsova-Sarafinovska, Cemal, Akay, Ahmet, Sayal, Nadica, Matevska, Ljubica, Suturkova, Koray, Erten, Yaşar, Ozgök, Aleksandar, Dimovski, and Ahmet, Aydin
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Aged, 80 and over ,Male ,Genotype ,Turkey ,Risk Factors ,Superoxide Dismutase ,Age Factors ,Humans ,Prostatic Neoplasms ,Middle Aged ,Polymorphism, Single Nucleotide ,Genetic Association Studies ,Aged - Abstract
Manganese superoxide dismutase (MnSOD) is the most effective antioxidant enzyme in mitochondria and protects cells from reactive oxygen species-induced oxidative damage. The aim of this study was to investigate the association between MnSOD Ala-9 Val gene polymorphism and prostate cancer (PCa) risk in Turkish men with prostate cancer. 33 patients with PCa and 81 control individuals were included in the study. We observed an association between MnSOD Ala/Ala frequency and a higher PCa risk. In addition, we found that the increased risk of early-onset PCa (under age of 65) in the men homozygous for Ala allele was higher than the men homozygous for Val allele. However, we determined that MnSOD Ala-9 Val genotype was not associated with the aggressiveness of the disease. The results of our study suggest that MnSOD Ala/Ala genotype may influence on early-onset of PCa patients, but no effect on subsequent development of the disease in Turkish men. However, our study has a limitation that is small numbers of individuals for cases and controls. Therefore, the presented study limited our statistical power to fully investigate the gene polymorphism on cancer risk.
- Published
- 2012
15. Evaluation of Plasma Nitrite/Nitrate Levels in Prostate Cancer, Benign Prostatic Hyperplasia Patients and Healthy Individuals
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Ayhan Savaser, Ahmet Aydin, Onur Erdem, Koray Erten, Aleksandar Dimovski, Yasar Ozgok, Ayşe Eken, Zorica Arsova-Sarafinovska, and Ahmet Sayal
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PCA3 ,medicine.medical_specialty ,business.industry ,Urology ,General Medicine ,Hyperplasia ,Toxicology ,medicine.disease ,chemistry.chemical_compound ,Prostate cancer ,chemistry ,Nitrate ,Healthy individuals ,medicine ,Nitrite ,business - Published
- 2008
16. Luminal suture thread as a guide for anastomosis: a new vasovasostomy technique
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Mete Kilciler, Lütfü Tahmaz, Ahmet Fuat Peker, Koray Erten, Selahattin Bedir, and Erkan Demir
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Infertility ,Adult ,Male ,medicine.medical_specialty ,medicine.diagnostic_test ,Sutures ,business.industry ,medicine.medical_treatment ,Vasovasostomy ,Anastomosis, Surgical ,Vasectomy ,Obstetrics and Gynecology ,Vasectomy reversal ,Semen analysis ,Anastomosis ,medicine.disease ,Sperm ,Surgery ,Reproductive Medicine ,medicine ,Humans ,business ,Prolene - Abstract
Objective To use a new vasovasostomy technique for reversal of vasectomy. Design Case report. Setting Clinical and academic research environment. Patient A patient who had undergone vasectomy. Intervention We used 4/0 prolene as a guide during anastomosis for reversal of vasectomy. Main Outcome Measure Semen analysis. Result(s) Three months after the operation, the spermiogram showed the sperm count, the percentage of normal morphologic sperm, progressive motility, and vitality as 9 million/L, 70%, 33%, and 60%, respectively. Six months later, the spermiogram was repeated and the following results were obtained: the sperm count, the percentage of normal morphologic sperm, progressive motility, and vitality as 14 million/L, 65%, 40%, and 65%, respectively. Conclusion(s) This new technique is cost-effective, easy, cheap, and less time-consuming, and has a high success rate.
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- 2006
17. Using two ipsilateral double j ureteral stents for extrinsic ureteral obstruction due to colon carcinoma
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Onder Ors, Selahattin Bedir, Fikret Erdemir, Yasar Ozgok, Mete Kilciler, Koray Erten, and Hidayet Coban
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Adult ,Male ,medicine.medical_specialty ,Urology ,medicine.medical_treatment ,urologic and male genital diseases ,Prosthesis Design ,Extrinsic ureteral obstruction ,Functional Laterality ,Prosthesis Implantation ,Ureter ,Colon carcinoma ,medicine ,Humans ,urogenital system ,business.industry ,Carcinoma ,Stent ,Urography ,Ureteral stents ,Cystoscopy ,equipment and supplies ,female genital diseases and pregnancy complications ,Surgery ,surgical procedures, operative ,medicine.anatomical_structure ,Colonic Neoplasms ,Stents ,business ,Follow-Up Studies ,Ureteral Obstruction - Abstract
Although double J (DJ) ureteral stents are widely used in extrinsic ureteral obstruction, there are few studies using ipsilateral two DJ stents in the same ureter. We report using ipsilateral two ureteral DJ stents in the same ureter in a patient with extrinsic ureteral obstruction due to colon carcinoma.
- Published
- 2005
18. Subject Index Vol. 79, 2007
- Author
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K.K. Bhomi, Bo Dai, A. Blandino, Cemal Göktaş, Francesca Vichi, F. Ciolino, Francis Vacherot, Manit Arya, Valiallah Azizi, Ali Thwaini, A.L. Morton, Omer F. Karakas, Mehdi Salehipour, P.A. McArdle, Riccardo Bartoletti, J. Slade Hubbard, Isao Hara, Ding Wei Ye, Volkan Tugcu, Iqbal S. Shergill, Kerem Inanoglu, Erkan Demir, Selcuk Sahin, Selahattin Bedir, Antonio S. Salinas-Sánchez, Sadık Görür, D. Santoro, Masato Fujisawa, José M. Giménez-Bachs, Erik Kouba, Carmen Pérez Romero, Toshifumi Kurahashi, Yasar Candan, Shunsuke Nobata, Z. Hotiana, Ahmet Namık Kiper, G. Bellinghieri, Shi Lin Zhang, H.H. Lim, Seiichiro Ozono, María J. Donate-Moreno, Selami Albayrak, Shinsuke Hayami, Yutaka Matsuyama, Luca Cindolo, Vedat Köksal, Miguel Segura-Martín, Ali Ihsan Tasci, María del Puerto López del Amo González, Francisco Sánchez-Sánchez, Hideaki Miyake, Umberto Farina, Yi Jun Shen, Onder Canguven, Yılmaz Ordekci, Clara Bermúdez-Tamayo, Héctor Pastor-Navarro, Mohsen Kroup, B. Cagla Ozbakis Akkurt, Toshiyuki Un-no, Kimio Fujita, Atsushi Takenaka, Fatih Zorluoglu, R.J.T. Alexander, Ibrahim Hernández-Millán, Takashi Tominaga, Raj S. Pruthi, Gianluca Giubilei, Abdolaziz Khezri, José Jesús Martín Martín, Monica Cantile, Nader Tanideh, V. Savica, C.J. Adams, Eric Wallen, Hai Liang Zhang, Koray Erten, Cenk Kilic, Xu Dong Yao, Ahmad Monabbati, Seijiro Honma, Stéphane Terry, Hamed Jalaeian, Zahran Budair, Hüseyin Aydemir, Yao Zhu, Yasuo Ohashi, Makoto Fujime, Alexandre de la Taille, Manuel Atienzar-Tobarra, Fumitaka Shimizu, D.T. Consigliere, Julio Escribano-Martínez, Wen Zhang, A. Magistro, Mete Kilciler, Antonio Costanzi, Ahmet Fuat Peker, H.Y. Tiong, P. Monardo, Juan G. Lorenzo-Romero, B. Vissamsetti, Hiroshi Sudoko, and T. Tony Cai
- Subjects
Index (economics) ,business.industry ,Urology ,Statistics ,Medicine ,Subject (documents) ,business - Published
- 2007
19. 266: The Effect of Prostate Volume on Complications after Radical Retropubic Prostatectomy
- Author
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Yasar Ozgok, Hidayet Coban, Mete Kilciler, Ahmet Fuat Peker, Fikret Erdemir, Koray Erten, and Selahattin Bedir
- Subjects
medicine.medical_specialty ,medicine.anatomical_structure ,business.industry ,Prostate ,Urology ,medicine.medical_treatment ,Medicine ,business ,Radical retropubic prostatectomy ,Volume (compression) - Published
- 2006
20. Subject Index Vol. 75, 2005
- Author
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Giulio Nicita, Huey-Yi Chen, N.S. Johal, Selahattin Bedir, Dario Nicolosi, Ming-Tsung Lai, M. V. C. De Silva, Francois Desgrandchamps, Ying-Chin Ko, Dogan Unal, I.M. Tavolini, F. Pinto, Aristotelis G. Anastasiadis, Wen-Chi Chen, Ömür Ataoğlu, Gagan Gautam, Pranjal R Modi, Angelo Porreca, Rudolf Hartung, Vincenzo Li Marzi, Mete Kilciler, Eugenio Di Grazia, John P. Gearhart, Rajiv Goel, Destito A, Chao-I Wu, E. Crucitta, Tahsin Turunc, P. Bassi, Koray Erten, Chung-Hsiung Huang, Onder Ors, L. Managadze, Zaza Mezvrishvili, Sharad Dodia, S.N. Jayasena, Muzaffer Eroğlu, Maria Teresa Filocamo, Jean Marc Duclos, R.O. Plail, F. Dal Moro, Roger Paul, S. Corvin, Alessandro D'Addessi, Anis Aribogan, Fuu-Jen Tsai, Chih-Ming Lu, Hasan Bakırtaş, E. Dattolo, Oguz Acar, Arnulf Stenzl, Narmada P. Gupta, J.T.N. Ariyasinghe, Yasar Ozgok, Marco Racioppi, Michael Alschibaja, L. Marini, Sule Akin, S.A.S. Gunawardena, Aylin Kanli, Giampaolo Delicato, Wolfgang Sturm, C. Kouriefs, Markus A. Kuczyk, M. Derya Balbay, Mehmet Doğan Gülkaç, Hidayet Coban, Ercan Yeni, Ashok K. Hemal, Pierre Teillac, Nazario Foschi, Ayhan Verit, Jörg Massmann, Mathias Wegner, Hsi-Chin Wu, Paul Meria, Mustafa Cengiz, Meng-Chu Chung, Fikret Erdemir, Surendra B. Kolla, Dominic Frimberger, Monish Aron, Meltem Ozlen Dillioglugil, Hale Maral Kir, Stéphane Milcent, Pierre Mongiat-Artus, Ozdal Dillioglugil, Maria Cristina Paoletti, Michele Marzocco, L. Apthorp, D.M.R. Gunawardena, Ersin Çimentepe, V. De Marco, Ali Unsal, M. Zucchetti, Rajiv Yadav, Lei Wan, Donata Villari, F. Longo, Atilla Aridogan, Hacı Kahya Ozdogan, and Armin Funk
- Subjects
Index (economics) ,business.industry ,Urology ,Statistics ,Medicine ,Subject (documents) ,business - Published
- 2005
21. Glutathione peroxidase 1 (GPX1) genetic polymorphism, erythrocyte GPX activity, and prostate cancer risk
- Author
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Yasar Ozgok, Aleksandar Dimovski, Ayhan Savaser, Onur Erdem, Ayşe Eken, Zorica Arsova-Sarafinovska, Koray Erten, Ahmet Sayal, and Ahmet Aydin
- Subjects
Prostate cancer risk ,GPX1 ,Immunology ,Cancer research ,General Medicine ,Biology ,Toxicology - Published
- 2009
22. Evaluation of plasma 8-OHdG levels in prostate cancer, benign prostatic hyperplasia patients and healthy individuals
- Author
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Ahmet Aydin, Ahmet Sayal, Onur Erdem, Ayhan Savaser, Koray Erten, Yasar Ozgok, Aleksandar Dimovski, Ayşe Eken, and Zorica Arsova-Sarafinovska
- Subjects
PCA3 ,Oncology ,medicine.medical_specialty ,business.industry ,Urology ,General Medicine ,Hyperplasia ,Toxicology ,medicine.disease ,Prostate cancer ,Internal medicine ,Healthy individuals ,medicine ,business - Published
- 2008
23. 1265: Comparing Two Local Anesthesia Techniques for Extracorporeal Shock Wave Lithotripsy
- Author
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Erkan Demir, Mete Kilciler, Selahattin Bedir, Koray Erten, and Yasar Ozgok
- Subjects
Urology - Published
- 2007
24. Pain Scores and Local Anesthesia for Transrectal Ultrasound-Guided Prostate Biopsy in Patients with Anorectal Pathologies.
- Author
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Erkan Demir, Mete Kilicer, Selahattin Bedir, Guldem Kilciler, Koray Erten, and Yasar Ozgok
- Subjects
DIMETHYL sulfoxide ,LIDOCAINE ,ULTRASONIC imaging ,PATIENTS - Abstract
Purpose The aim of the present randomized study was to evaluate the efficacy of lidocaine gel compared with dimethylsulfoxide (DMSO) with lidocaine for transrectal ultrasonography (TRUS)-guided prostate biopsy in patients with anorectal pathologies.Patients and Methods Sixty-two patients were randomly divided into two equal groups. Group 1 was given 10 mL of 2 lidocaine gel intrarectally 10 minutes before the biopsy. Group 2 was given 10 mL of intrarectal 40 DMSO with an amount of lidocaine equal to that in the lidocaine gel 10 minutes before the procedure. The degree of pain was rated by patients using a 10-point visual analog scale.Results The pain scores for probe insertion were significantly lower for group 2 (3.15 ± 1.41) than for group 1 (4.58 ± 160) (P 0.01). No significant differences were found between the pain scores of the two groups for biopsy-needle insertion (P 0.62).Conclusions Dimethylsulfoxide with lidocaine instilled into the rectum is a simple, safe, rapid-acting, and effective method of anesthesia delivery before TRUS-guided prostate biopsy in patients with anorectal pathologies. [ABSTRACT FROM AUTHOR]
- Published
- 2007
- Full Text
- View/download PDF
25. Penile Fracture in A Patient With Spinal Cord Injury: A Case Report.
- Author
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GÜZelkÜÇÜK, Ümüt, Duman, İltekin, Koray ERTEN, Bilge YILMAZ, and Tan, Arif Kenan
- Subjects
PENIS diseases ,SPINAL cord injuries ,DIAGNOSIS - Published
- 2013
- Full Text
- View/download PDF
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