303 results on '"Kolkhir, Pavel"'
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2. The European Network for IgE-Mediated Autoimmunity and Autoallergy (ENIGMA) initiative
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Kolkhir, Pavel, Altrichter, Sabine, Badloe, Fariza Mishaal Saiema, Belasri, Hafsa, Charles, Nicolas, De Vriese, Shauni, Gutermuth, Jan, Huygen, Lisa, Kocatürk, Emek, Kortekaas Krohn, Inge, Muñoz, Melba, Moñino-Romero, Sherezade, Reber, Laurent L., Scheffel, Jörg, Steinert, Carolin, Xiang, Yi-Kui, and Maurer, Marcus
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- 2024
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3. Type 2 chronic inflammatory diseases: targets, therapies and unmet needs
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Kolkhir, Pavel, Akdis, Cezmi A., Akdis, Mübeccel, Bachert, Claus, Bieber, Thomas, Canonica, Giorgio Walter, Guttman-Yassky, Emma, Metz, Martin, Mullol, Joaquim, Palomares, Oscar, Renz, Harald, Ständer, Sonja, Zuberbier, Torsten, and Maurer, Marcus
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- 2023
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4. Emerging Therapeutics in Chronic Urticaria
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Muñoz, Melba, Kocatürk, Emek, Maurer, Marcus, and Kolkhir, Pavel
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- 2024
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5. The Definition, Classification, and History of Urticaria
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Maurer, Marcus, Pereira, Manuel P., and Kolkhir, Pavel
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- 2024
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6. Definition, acronyms, nomenclature, and classification of angioedema (DANCE): AAAAI, ACAAI, ACARE, and APAAACI DANCE consensus
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Reshef, Avner, Buttgereit, Thomas, Betschel, Stephen D., Caballero, Teresa, Farkas, Henriette, Grumach, Anete S., Hide, Michihiro, Jindal, Ankur K., Longhurst, Hilary, Peter, Jonathan, Riedl, Marc A., Zhi, Yuxiang, Aberer, Werner, Abuzakouk, Mohamed, Al Farsi, Tariq, Al Sukaiti, Nashat, Al-Ahmad, Mona, Altrichter, Sabine, Aygören-Pürsün, Emel, Baeza, Maria Luisa, Bara, Noemi Anna, Bauer, Andrea, Bernstein, Jonathan A., Boccon-Gibod, Isabelle, Bonnekoh, Hanna, Bouillet, Laurence, Brzoza, Zenon, Bygum, Anette, Calderon, Oscar, de Albuquerque Campos, Regis, Campos Romero, Freya Helena, Cancian, Mauro, Chong-Neto, Herberto Jose, Christoff, George, Cimbollek, Stefan, Cohn, Danny M., Craig, Timothy, Danilycheva, Inna, Darlenski, Razvigor, Du-Thanh, Aurélie, Ensina, Luis Felipe, Fomina, Daria, Fonacier, Luz, Fukunaga, Atsushi, Gelincik, Asli, Giavina-Bianchi, Pedro, Godse, Kiran, Gompels, Mark, Goncalo, Margarida, Gotua, Maia, Guidos-Fogelbach, Guillermo, Guilarte, Mar, Kasperska-Zajac, Alicja, Katelaris, Constance H., Kinaciyan, Tamar, Kolkhir, Pavel, Kulthanan, Kanokvalai, Kurowski, Marcin, Latysheva, Elena, Lauerma, Antti, Launay, David, Lleonart, Ramon, Lumry, William, Malbran, Alejandro, Ali, Ramzy Mohammed, Nasr, Iman, Nieto-Martinez, Sandra, Parisi, Claudio, Pawankar, Ruby, Piñero-Saavedra, Macarena, Popov, Todor A., Porebski, Grzegorz, Prieto Garcia, Alicia, Pyatilova, Polina, Rudenko, Michael, Sekerel, Bulent Enis, Serpa, Faradiba Sarquis, Sheikh, Farrukh, Siebenhaar, Frank, Soria, Angèle, Staevska, Maria, Staubach, Petra, Stobiecki, Marcin, Thomsen, Simon Francis, Triggiani, Massimo, Valerieva, Anna, Valle, Solange, Van Dinh, Nguyen, Vera Ayala, Carolina Elisa, Zalewska-Janowska, Anna, Zanichelli, Andrea, Magerl, Markus, and Maurer, Marcus
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- 2024
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7. Chronic urticaria: unmet needs, emerging drugs, and new perspectives on personalised treatment
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Zuberbier, Torsten, Ensina, Luis Felipe, Giménez-Arnau, Ana, Grattan, Clive, Kocatürk, Emek, Kulthanan, Kanokvalai, Kolkhir, Pavel, and Maurer, Marcus
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- 2024
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8. Non–Skin Related Symptoms Are Common in Chronic Spontaneous Urticaria and Linked to Active and Uncontrolled Disease: Results From the Chronic Urticaria Registry
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Pyatilova, Polina, Hackler, Yana, Aulenbacher, Felix, Asero, Riccardo, Bauer, Andrea, Bizjak, Mojca, Day, Cascia, Dissemond, Joachim, Du-Thanh, Aurélie, Fomina, Daria, Giménez-Arnau, Ana M., Grattan, Clive, Gregoriou, Stamatis, Hawro, Tomasz, Kasperska-Zajac, Alicja, Khoshkhui, Maryam, Kocatürk, Emek, Kovalkova, Elena, Kulthanan, Kanokvalai, Kuznetsova, Elizaveta, Makris, Michael, Mukhina, Olga, Pesqué, David, Peter, Jonny, Salameh, Pascale, Siebenhaar, Frank, Sikora, Agnieszka, Staubach, Petra, Tuchinda, Papapit, Zamłyński, Mateusz, Weller, Karsten, Maurer, Marcus, and Kolkhir, Pavel
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- 2024
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9. Patient-Reported Outcome Measures in Atopic Dermatitis and Chronic Urticaria Are Underused in Clinical Practice
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Cherrez-Ojeda, Ivan, Bousquet, Jean, Giménez-Arnau, Ana, Godse, Kiran, Krasowska, Dorota, Bartosińska, Joanna, Szczepanik-Kułak, Paulina, Wawrzycki, Bartłomiej, Kolkhir, Pavel, Allenova, Anastasiia, Allenova, Andrey, Tkachenko, Sergey, Teovska Mitrevska, Natasa, Mijakoski, Dragan, Stoleski, Sasho, Kolacinska-Flont, Marta, Kuprys-Lipinska, Izabela, Molinska, Joanna, Kasperska-Zając, Alicja, Zajac, Magdalena, Zamlynski, Mateusz, Mihaltan, Florin, Ulmeanu, Ruxandra, Zalewska-Janowska, Anna, Tomaszewska, Katarzyna, Al-Ahmad, Mona, Al-Nesf, Maryam Ali, Ibrahim, Tayseer, Aqel, Sami, Pesqué, David, Rodríguez-González, Mónica, Wakida-Kuzunoki, Guillermo Hideo, Ramon, German, Ramon, Gonzalo, Neisinger, Sophia, Bonnekoh, Hanna, Rukhadze, Maia, Khoshkhui, Maryam, Fomina, Daria, Larenas-Linnemann, Désirée, Košnik, Mitja, Oztas Kara, Rabia, Caballero López, Chrystopherson Gengyny, Liu, Qiang, Ivancevich, Juan Carlos, Ensina, Luis Felipe, Rosario, Nelson, Kvedariene, Violeta, Ben-Shoshan, Moshe, Criado, Roberta Fachini Jardim, Bauer, Andrea, Cherrez, Annia, Chong-Neto, Herberto, Rojo-Gutierrez, Maria Isabel, Rudenko, Michael, Larco Sousa, José Ignacio, Lesiak, Aleksandra, Matos, Edgar, Muñoz, Nelson, Tinoco, Ivan, Moreno, Jaime, Crespo Shijin, Carolina, Hinostroza Logroño, Romina, Sagñay, Juan, Faytong-Haro, Marco, Robles-Velasco, Karla, Zuberbier, Torsten, and Maurer, Marcus
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- 2024
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10. The diagnostic workup for systemic mastocytosis differs from consensus recommendations: Results of a worldwide survey
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Pyatilova, Polina, Bernstein, Jonathan A., Aulenbacher, Felix, Borges, Mario Sanchez, Dimitrijević, Saša, Hoehn, Gerard, Maurer, Marcus, Kolkhir, Pavel, and Siebenhaar, Frank
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- 2023
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11. Patients With Chronic Spontaneous Urticaria Who Have Wheals, Angioedema, or Both, Differ Demographically, Clinically, and in Response to Treatment—Results From CURE
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Buttgereit, Thomas, Vera, Carolina, Aulenbacher, Felix, Church, Martin K., Hawro, Tomasz, Asero, Riccardo, Bauer, Andrea, Bizjak, Mojca, Bouillet, Laurence, Dissemond, Joachim, Fomina, Daria, Giménez-Arnau, Ana M., Grattan, Clive, Gregoriou, Stamatios, Kulthanan, Kanokvalai, Kasperska-Zajac, Alicja, Kocatürk, Emek, Makris, Michael, Kolkhir, Pavel, Weller, Karsten, Magerl, Markus, and Maurer, Marcus
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- 2023
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12. Urticaria exacerbations and adverse reactions in patients with chronic urticaria receiving COVID-19 vaccination: Results of the UCARE COVAC-CU study
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Kocatürk, Emek, Salameh, Pascale, Sarac, Esra, Vera Ayala, Carolina E., Thomsen, Simon Francis, Zuberbier, Torsten, Ensina, Luis Felipe, Popov, Todor A., van Doorn, Martijn B.A., Giménez-Arnau, Ana Maria, Asero, Riccardo, Criado, Paulo Ricardo, Aarestrup, Fernando M., AbdulHameed Ansari, Zainab, Al Abri, Salma, Al-Ahmad, Mona, Al Hinai, Bushra, Allenova, Anastasiia, Al-Nesf, Maryam, Altrichter, Sabine, Arnaout, Rand, Bartosińska, Joanna, Bauer, Andrea, Bernstein, Jonathan A., Bizjak, Mojca, Bonnekoh, Hanna, Bouillet, Laurence, Brzoza, Zenon, Calvalcanti Dela Bianca Melo, Ana Caroline, Campinhos, Fernanda L., Carne, Emily, Purayil, Saleema Cherichi, Cherrez-Ojeda, Ivan, Chong-Neto, Herberto Jose, Christoff, George, Conlon, Niall, Jardim Criado, Roberta Fachini, Cvenkel, Klara, Damadoglu, Ebru, Danilycheva, Inna, Day, Cascia, de Montjoye, Laurence, Demir, Semra, Ferucci, Silvia Mariel, Fomina, Daria, Fukunaga, Atsushi, Garcia, Elizabeth, Gelincik, Asli, Göbel, Joe Hannah, Godse, Kiran, Gonçalo, Margarida, Gotua, Maia, Grattan, Clive, Gugala, Agata, Guillet, Carole, Kalyoncu, Ali Fuat, Karakaya, Gul, Kasperska-Zając, Alicja, Katelaris, Constance H., Khoshkhui, Maryam, Kleinheinz, Andreas, Kolacinska-Flont, Marta, Kolkhir, Pavel, Košnik, Mitja, Krasowska, Dorota, Kumaran, Muthu Sendhil, Kuprys-Lipinska, Izabela, Kurowski, Marcin, Kuznetsova, Elizaveta V., Larenas-Linnemann, Désirée, Lebedkina, Marina S., Lee, Youngsoo, Makris, Michael, Gómez, René Maximiliano, Nasr, Iman, Neisinger, Sophia, Oda, Yoshiko, Kara, Rabia Öztaş, Palitot, Esther Bastos, Papapostolou, Niki, Salvador Parisi, Claudio Alberto, Pesque, David, Peter, Jonathan, Petkova, Elena, Ridge, Katie, Rudenko, Michael, Rutkowski, Krzysztof, Saini, Sarbjit S., Salman, Andac, Sanchez, Jorge, Şekerel, Bülent, Serdotetskova, Sofia A., Serpa, Faradiba S., Dikicier, Bahar Sevimli, Sidiropoulos, Nikitas, Sikora, Agnieszka, Sørensen, Jennifer Astrup, Soria, Angele, Kucuk, Ozlem Su, Thalappil, Sherin Rahim, Tomaszewska, Katarzyna, Tuncay, Gulseren, Unal, Derya, Valle, Solange, van Lindonk, Esmee, Vestergaard, Christian, Meshkova, Raisa Y., Vitchuk, Aleksandr, Xepapadaki, Paraskevi, Ye, Young-Min, Zalewska-Janowska, Anna, Zamlynski, Mateusz, and Maurer, Marcus
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- 2023
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13. Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019
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Wu, Dongze, Jin, Yingzhao, Xing, Yuhan, Abate, Melsew Dagne, Abbasian, Mohammadreza, Abbasi-Kangevari, Mohsen, Abbasi-Kangevari, Zeinab, Abd-Allah, Foad, Abdelmasseh, Michael, Abdollahifar, Mohammad-Amin, Abdulah, Deldar Morad, Abedi, Aidin, Abedi, Vida, Abidi, Hassan, Aboagye, Richard Gyan, Abolhassani, Hassan, Abuabara, Katrina, Abyadeh, Morteza, Addo, Isaac Yeboah, Adeniji, Kayode Nelson, Adepoju, Abiola Victor, Adesina, Miracle Ayomikun, Sakilah Adnani, Qorinah Estiningtyas, Afarideh, Mohsen, Aghamiri, Shahin, Agodi, Antonella, Agrawal, Anurag, Aguilera Arriagada, Constanza Elizabeth, Ahmad, Aqeel, Ahmad, Danish, Ahmad, Sajjad, Ahmad, Sohail, Ahmadi, Ali, Ahmed, Ali, Ahmed, Ayman, Aithala, Janardhana P., Ajadi, Abdullateef Abiodun, Ajami, Marjan, Akbarzadeh-Khiavi, Mostafa, Alahdab, Fares, AlBataineh, Mohammad T., Alemi, Sharifullah, Saeed Al-Gheethi, Adel Ali, Ali, Liaqat, Alif, Sheikh Mohammad, Almazan, Joseph Uy, Almustanyir, Sami, Alqahtani, Jaber S., Alqasmi, Ibrahim, Khan Altaf, Ihsan Ullah, Alvis-Guzman, Nelson, Alvis-Zakzuk, Nelson J., Al-Worafi, Yaser Mohammed, Aly, Hany, Amani, Reza, Amu, Hubert, Amusa, Ganiyu Adeniyi, Andrei, Catalina Liliana, Ansar, Adnan, Ansariniya, Hossein, Anyasodor, Anayochukwu Edward, Arabloo, Jalal, Arefnezhad, Reza, Arulappan, Judie, Asghari-Jafarabadi, Mohammad, Ashraf, Tahira, Atata, Jamila Abdulhamid, Athari, Seyyed Shamsadin, Atlaw, Daniel, Wahbi Atout, Maha Moh'd, Aujayeb, Avinash, Awan, Asma Tahir, Ayatollahi, Haleh, Azadnajafabad, Sina, Azzam, Ahmed Y., Badawi, Alaa, Badiye, Ashish D., Bagherieh, Sara, Baig, Atif Amin, Bantie, Berihun Bantie, Barchitta, Martina, Bardhan, Mainak, Barker-Collo, Suzanne Lyn, Barone-Adesi, Francesco, Batra, Kavita, Bayileyegn, Nebiyou Simegnew, Behnoush, Amir Hossein, Belgaumi, Uzma Iqbal, Bemanalizadeh, Maryam, Bensenor, Isabela M., Beyene, Kebede A., Bhagavathula, Akshaya Srikanth, Bhardwaj, Pankaj, Bhaskar, Sonu, Bhat, Ajay Nagesh, Bitaraf, Saeid, Bitra, Veera R., Boloor, Archith, Bora, Kaustubh, Botelho, João Silva, Buchbinder, Rachelle, Calina, Daniela, Cámera, Luis Alberto, Carvalho, Andre F., Kai Chan, Jeffrey Shi, Chattu, Vijay Kumar, Abebe, Endeshaw Chekol, Chichagi, Fatemeh, Choi, Sungchul, Chou, Tzu-Chieh, Chu, Dinh-Toi, Coberly, Kaleb, Costa, Vera Marisa, Couto, Rosa A.S., Cruz-Martins, Natália, Dadras, Omid, Dai, Xiaochen, Damiani, Giovanni, Dascalu, Ana Maria, Dashti, Mohsen, Debela, Sisay Abebe, Dellavalle, Robert Paul, Demetriades, Andreas K., Demlash, Alemayehu Anley, Deng, Xinlei, Desai, Hardik Dineshbhai, Desai, Rupak, Rahman Dewan, Syed Masudur, Dey, Sourav, Dharmaratne, Samath Dhamminda, Diaz, Daniel, Dibas, Mahmoud, Dinis-Oliveira, Ricardo Jorge, Diress, Mengistie, Do, Thanh Chi, Doan, Duy Khanh, Dodangeh, Masoud, Dodangeh, Milad, Dongarwar, Deepa, Dube, John, Dziedzic, Arkadiusz Marian, Ed-Dra, Abdelaziz, Edinur, Hisham Atan, Eissazade, Negin, Ekholuenetale, Michael, Ekundayo, Temitope Cyrus, Elemam, Noha Mousaad, Elhadi, Muhammed, Elmehrath, Ahmed O., Abdou Elmeligy, Omar Abdelsadek, Emamverdi, Mehdi, Emeto, Theophilus I., Esayas, Hawi Leul, Eshetu, Habitu Birhan, Etaee, Farshid, Fagbamigbe, Adeniyi Francis, Faghani, Shahriar, Fakhradiyev, Ildar Ravisovich, Fatehizadeh, Ali, Fathi, Mobina, Feizkhah, Alireza, Fekadu, Ginenus, Fereidouni, Mohammad, Fereshtehnejad, Seyed-Mohammad, Fernandes, João C., Ferrara, Pietro, Fetensa, Getahun, Filip, Irina, Fischer, Florian, Foroutan, Behzad, Foroutan, Masoud, Fukumoto, Takeshi, Ganesan, Balasankar, Belete Gemeda, Belete Negese, Ghamari, Seyyed-Hadi, Ghasemi, MohammadReza, Gholamalizadeh, Maryam, Gill, Tiffany K., Gillum, Richard F., Goldust, Mohamad, Golechha, Mahaveer, Goleij, Pouya, Golinelli, Davide, Goudarzi, Houman, Guan, Shi-Yang, Guo, Yang, Gupta, Bhawna, Gupta, Veer Bala, Gupta, Vivek Kumar, Haddadi, Rasool, Hadi, Najah R., Halwani, Rabih, Haque, Shafiul, Hasan, Ikramul, Hashempour, Reza, Hassan, Amr, Hassan, Treska S., Hassanzadeh, Sara, Hassen, Mohammed Bheser, Haubold, Johannes, Hayat, Khezar, Heidari, Golnaz, Heidari, Mohammad, Heidari-Soureshjani, Reza, Herteliu, Claudiu, Hessami, Kamran, Hezam, Kamal, Hiraike, Yuta, Holla, Ramesh, Hosseini, Mohammad-Salar, Huynh, Hong-Han, Hwang, Bing-Fang, Ibitoye, Segun Emmanuel, Ilic, Irena M., Ilic, Milena D., Iranmehr, Arad, Iravanpour, Farideh, Ismail, Nahlah Elkudssiah, Iwagami, Masao, Iwu, Chidozie C.D., Jacob, Louis, Jafarinia, Morteza, Jafarzadeh, Abdollah, Jahankhani, Kasra, Jahrami, Haitham, Jakovljevic, Mihajlo, Jamshidi, Elham, Jani, Chinmay T., Janodia, Manthan Dilipkumar, Jayapal, Sathish Kumar, Jayaram, Shubha, Jeganathan, Jayakumar, Jonas, Jost B., Joseph, Abel, Joseph, Nitin, Joshua, Charity Ehimwenma, Vaishali, K., Kaambwa, Billingsley, Kabir, Ali, Kabir, Zubair, Kadashetti, Vidya, Kaliyadan, Feroze, Kalroozi, Fatemeh, Kamal, Vineet Kumar, Kandel, Amit, Kandel, Himal, Kanungo, Srikanta, Karami, Jafar, Karaye, Ibraheem M., Karimi, Hanie, Kasraei, Hengameh, Kazemian, Sina, Kebede, Sewnet Adem, Keikavoosi-Arani, Leila, Keykhaei, Mohammad, Khader, Yousef Saleh, Khajuria, Himanshu, Khamesipour, Faham, Khan, Ejaz Ahmad, Khan, Imteyaz A., Khan, Maseer, Khan, Md Jobair, Khan, Moien A.B., Khan, Muhammad Arslan, Khatatbeh, Haitham, Khatatbeh, Moawiah Mohammad, Khateri, Sorour, Khayat Kashani, Hamid Reza, Kim, Min Seo, Kisa, Adnan, Kisa, Sezer, Koh, Hyun Yong, Kolkhir, Pavel, Korzh, Oleksii, Kotnis, Ashwin Laxmikant, Koul, Parvaiz A., Koyanagi, Ai, Krishan, Kewal, Kuddus, Mohammed, Kulkarni, Vishnutheertha Vishnutheertha, Kumar, Narinder, Kundu, Satyajit, Kurmi, Om P., La Vecchia, Carlo, Lahariya, Chandrakant, Laksono, Tri, Lám, Judit, Latief, Kamaluddin, Lauriola, Paolo, Lawal, Basira Kankia, Thu Le, Thao Thi, Bich Le, Trang Thi, Lee, Munjae, Lee, Seung Won, Lee, Wei-Chen, Lee, Yo Han, Lenzi, Jacopo, Levi, Miriam, Li, Wei, Ligade, Virendra S., Lim, Stephen S., Liu, Gang, Liu, Xuefeng, Llanaj, Erand, Lo, Chun-Han, Machado, Vanessa Sintra, Maghazachi, Azzam A., Mahmoud, Mansour Adam, Mai, Tuan A., Majeed, Azeem, Sanaye, Pantea Majma, Makram, Omar Mohamed, Rad, Elaheh Malakan, Malhotra, Kashish, Malik, Ahmad Azam, Malik, Iram, Mallhi, Tauqeer Hussain, Malta, Deborah Carvalho, Mansournia, Mohammad Ali, Mantovani, Lorenzo Giovanni, Martorell, Miquel, Masoudi, Sahar, Masoumi, Seyedeh Zahra, Mathangasinghe, Yasith, Mathews, Elezebeth, Mathioudakis, Alexander G., Maugeri, Andrea, Mayeli, Mahsa, Carabeo Medina, John Robert, Meles, Gebrekiros Gebremichael, Mendes, José João, Menezes, Ritesh G., Mestrovic, Tomislav, Michalek, Irmina Maria, Micheletti Gomide Nogueira de Sá, Ana Carolina, Mihretie, Ephrem Tesfaye, Nhat Minh, Le Huu, Mirfakhraie, Reza, Mirrakhimov, Erkin M., Misganaw, Awoke, Mohamadkhani, Ashraf, Mohamed, Nouh Saad, Mohammadi, Faezeh, Mohammadi, Soheil, Mohammed, Salahuddin, Mohammed, Shafiu, Mohan, Syam, Mohseni, Anita, Mokdad, Ali H., Momtazmanesh, Sara, Monasta, Lorenzo, Moni, Mohammad Ali, Moniruzzaman, Md, Moradi, Yousef, Morovatdar, Negar, Mostafavi, Ebrahim, Mousavi, Parsa, Mukoro, George Duke, Mulita, Admir, Mulu, Getaneh Baye, Murillo-Zamora, Efrén, Musaigwa, Fungai, Mustafa, Ghulam, Muthu, Sathish, Nainu, Firzan, Nangia, Vinay, Swamy, Sreenivas Narasimha, Natto, Zuhair S., Navaraj, Perumalsamy, Nayak, Biswa Prakash, Nazri-Panjaki, Athare, Negash, Hadush, Nematollahi, Mohammad Hadi, Nguyen, Dang H., Hien Nguyen, Hau Thi, Nguyen, Hien Quang, Nguyen, Phat Tuan, Nguyen, Van Thanh, Niazi, Robina Khan, Nikolouzakis, Taxiarchis Konstantinos, Nnyanzi, Lawrence Achilles, Noreen, Mamoona, Nzoputam, Chimezie Igwegbe, Nzoputam, Ogochukwu Janet, Oancea, Bogdan, Oh, In-Hwan, Okati-Aliabad, Hassan, Okonji, Osaretin Christabel, Okwute, Patrick Godwin, Olagunju, Andrew T., Olatubi, Matthew Idowu, Olufadewa, Isaac Iyinoluwa, Ordak, Michal, Otstavnov, Nikita, Owolabi, Mayowa O., Mahesh, P.A., Padubidri, Jagadish Rao, Pak, Anton, Pakzad, Reza, Palladino, Raffaele, Pana, Adrian, Pantazopoulos, Ioannis, Papadopoulou, Paraskevi, Pardhan, Shahina, Parthasarathi, Ashwaghosha, Pashaei, Ava, Patel, Jay, Pathan, Aslam Ramjan, Patil, Shankargouda, Paudel, Uttam, Pawar, Shrikant, Pedersini, Paolo, Pensato, Umberto, Pereira, David M., Pereira, Jeevan, Pereira, Maria Odete, Pereira, Renato B., Peres, Mario F.P., Perianayagam, Arokiasamy, Perna, Simone, Petcu, Ionela-Roxana, Pezeshki, Parmida Sadat, Pham, Hoang Tran, Philip, Anil K., Piradov, Michael A., Podder, Indrashis, Podder, Vivek, Poddighe, Dimitri, Sady Prates, Elton Junio, Qattea, Ibrahim, Radfar, Amir, Raee, Pourya, Rafiei, Alireza, Raggi, Alberto, Rahim, Fakher, Rahimi, Mehran, Rahimifard, Mahban, Rahimi-Movaghar, Vafa, Rahman, Md Obaidur, Ur Rahman, Mohammad Hifz, Rahman, Mosiur, Rahman, Muhammad Aziz, Rahmani, Amir Masoud, Rahmani, Mohamed, Rahmani, Shayan, Rahmanian, Vahid, Ramasubramani, Premkumar, Rancic, Nemanja, Rao, Indu Ramachandra, Rashedi, Sina, Rashid, Ahmed Mustafa, Ravikumar, Nakul, Rawaf, Salman, Mohamed Redwan, Elrashdy Moustafa, Rezaei, Nazila, Rezaei, Negar, Rezaei, Nima, Rezaeian, Mohsen, Ribeiro, Daniela, Rodrigues, Mónica, Buendia Rodriguez, Jefferson Antonio, Roever, Leonardo, Romero-Rodríguez, Esperanza, Saad, Aly M.A., Saddik, Basema, Sadeghian, Saeid, Saeed, Umar, Safary, Azam, Safdarian, Mahdi, Safi, Sher Zaman, Saghazadeh, Amene, Sagoe, Dominic, Sharif-Askari, Fatemeh Saheb, Sharif-Askari, Narjes Saheb, Sahebkar, Amirhossein, Sahoo, Harihar, Sahraian, Mohammad Ali, Sajid, Mirza Rizwan, Sakhamuri, Sateesh, Sakshaug, Joseph W., Saleh, Mohamed A., Salehi, Leili, Salehi, Sana, Farrokhi, Amir Salek, Samadzadeh, Sara, Samargandy, Saad, Samieefar, Noosha, Samy, Abdallah M., Sanadgol, Nima, Sanjeev, Rama Krishna, Sawhney, Monika, Saya, Ganesh Kumar, Schuermans, Art, Senthilkumaran, Subramanian, Sepanlou, Sadaf G., Sethi, Yashendra, Shafie, Mahan, Shah, Humaira, Shahid, Izza, Shahid, Samiah, Shaikh, Masood Ali, Sharfaei, Sadaf, Sharma, Manoj, Shayan, Maryam, Shehata, Hatem Samir, Sheikh, Aziz, Shetty, Jeevan K., Shin, Jae Il, Shirkoohi, Reza, Shitaye, Nebiyu Aniley, Shivakumar, K.M., Shivarov, Velizar, Shobeiri, Parnian, Siabani, Soraya, Sibhat, Migbar Mekonnen, Siddig, Emmanuel Edwar, Simpson, Colin R., Sinaei, Ehsan, Singh, Harpreet, Singh, Inderbir, Singh, Jasvinder A., Singh, Paramdeep, Singh, Surjit, Siraj, Md Shahjahan, Al Mamun Sohag, Abdullah, Solanki, Ranjan, Solikhah, Solikhah, Solomon, Yonatan, Soltani-Zangbar, Mohammad Sadegh, Sun, Jing, Szeto, Mindy D., Tabarés-Seisdedos, Rafael, Tabatabaei, Seyyed Mohammad, Tabish, Mohammad, Taheri, Ensiyeh, Tahvildari, Azin, Talaat, Iman M., Lukenze Tamuzi, Jacques J.L., Tan, Ker-Kan, Tat, Nathan Y., Oliaee, Razieh Tavakoli, Tavasol, Arian, Temsah, Mohamad-Hani, Thangaraju, Pugazhenthan, Tharwat, Samar, Tibebu, Nigusie Selomon, Vera Ticoalu, Jansje Henny, Tillawi, Tala, Tiruye, Tenaw Yimer, Tiyuri, Amir, Tovani-Palone, Marcos Roberto, Tripathi, Manjari, Tsegay, Guesh Mebrahtom, Tualeka, Abdul Rohim, Ty, Sree Sudha, Ubah, Chukwudi S., Ullah, Saif, Ullah, Sana, Umair, Muhammad, Umakanthan, Srikanth, Upadhyay, Era, Vahabi, Seyed Mohammad, Vaithinathan, Asokan Govindaraj, Tahbaz, Sahel Valadan, Valizadeh, Rohollah, Varthya, Shoban Babu, Vasankari, Tommi Juhani, Venketasubramanian, Narayanaswamy, Verras, Georgios-Ioannis, Villafañe, Jorge Hugo, Vlassov, Vasily, Vo, Danh Cao, Waheed, Yasir, Waris, Abdul, Welegebrial, Brhane Gebrehiwot, Westerman, Ronny, Wickramasinghe, Dakshitha Praneeth, Wickramasinghe, Nuwan Darshana, Willekens, Barbara, Woldegeorgis, Beshada Zerfu, Woldemariam, Melat, Xiao, Hong, Yada, Dereje Y., Yahya, Galal, Yang, Lin, Yazdanpanah, Fereshteh, Yon, Dong Keon, Yonemoto, Naohiro, You, Yuyi, Zahir, Mazyar, Zaidi, Syed Saoud, Zangiabadian, Moein, Zare, Iman, Zeineddine, Mohammad A., Zemedikun, Dawit T., Zeru, Naod Gebrekrstos, Zhang, Chen, Zhao, Hanqing, Zhong, Chenwen, Zielińska, Magdalena, Zoladl, Mohammad, Zumla, Alimuddin, Guo, Cui, and Tam, Lai-shan
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- 2023
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14. Global disparities in availability of epinephrine auto-injectors
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Tanno, Luciana Kase, Worm, Margitta, Ebisawa, Motohiro, Ansotegui, Ignacio J., Senna, Gianenrico, Fineman, Stanley, Geller, Mario, Gonzalez-Estrada, Alexei, Campbell, Dianne E., Leung, Agnes, Muraro, Antonella, Levin, Michael, Ortega Martell, Jose Antonio, Caminati, Marco, Kolkhir, Pavel, Le Pham, Duy, Darlenski, Razvigor, Esteban-Gorgojo, Ignacio, Rial, Manuel, Filipovic, Ivana, Chiarella, Sergio E., Cuervo-Pardo, Lyda, Kwong, Christina, Pozo-Beltran, Cezar Fireth, Trinh, Tu HK., Greenberger, Paul A., Turner, Paul J., Thong, Bernard Yu-Hor, Martin, Bryan, and Cardona, Victoria
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- 2023
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15. Urticarial Vasculitis Differs From Chronic Spontaneous Urticaria in Time to Diagnosis, Clinical Presentation, and Need for Anti-Inflammatory Treatment: An International Prospective UCARE Study
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Bonnekoh, Hanna, Jelden-Thurm, Jannis, Allenova, Anastasiia, Chen, Yudi, Cherrez-Ojeda, Ivan, Danilycheva, Inna, Dorofeeva, Irina, Jardim Criado, Roberta Fachini, Criado, Paulo Ricardo, Gelincik Akkor, Asli, Hawro, Tomasz, Kocatürk, Emek, Khoshkhui, Maryam, Metz, Martin, Nasr, Iman, Steć, Michał, Zhao, Zuotao, Aulenbacher, Felix, Salameh, Pascale, Altrichter, Sabine, Gonçalo, Margarida, Gimenez-Arnau, Ana, Maurer, Marcus, Krause, Karoline, and Kolkhir, Pavel
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- 2023
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16. Positive Basophil Tests Are Linked to High Disease Activity and Other Features of Autoimmune Chronic Spontaneous Urticaria: A Systematic Review
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Moñino-Romero, Sherezade, Hackler, Yana, Okas, Tiia-Linda, Grekowitz, Eva Maria, Fluhr, Joachim W., Hultsch, Vincent, Kiefer, Lea Alice, Pyatilova, Polina, Terhorst-Molawi, Dorothea, Xiang, Yi-Kui, Siebenhaar, Frank, Maurer, Marcus, and Kolkhir, Pavel
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- 2023
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17. Most Patients With Autoimmune Chronic Spontaneous Urticaria Also Have Autoallergic Urticaria, but Not ViceVersa
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Xiang, Yi-Kui, Kolkhir, Pavel, Scheffel, Jörg, Sauer, Merle, Vera, Carolina, Frischbutter, Stefan, Krause, Karoline, Siebenhaar, Frank, Metz, Martin, Maurer, Marcus, and Altrichter, Sabine
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- 2023
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18. Chronic urticaria and the pathogenic role of mast cells
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Elieh-Ali-Komi, Daniel, Metz, Martin, Kolkhir, Pavel, Kocatürk, Emek, Scheffel, Jörg, Frischbutter, Stefan, Terhorst-Molawi, Dorothea, Fox, Lena, and Maurer, Marcus
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- 2023
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19. Global burden of chronic respiratory diseases and risk factors, 1990–2019: an update from the Global Burden of Disease Study 2019
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Momtazmanesh, Sara, Moghaddam, Sahar Saeedi, Ghamari, Seyyed-Hadi, Rad, Elaheh Malakan, Rezaei, Negar, Shobeiri, Parnian, Aali, Amirali, Abbasi-Kangevari, Mohsen, Abbasi-Kangevari, Zeinab, Abdelmasseh, Michael, Abdoun, Meriem, Abdulah, Deldar Morad, Md Abdullah, Abu Yousuf, Abedi, Aidin, Abolhassani, Hassan, Abrehdari-Tafreshi, Zahra, Achappa, Basavaprabhu, Adane Adane, Denberu Eshetie, Adane, Tigist Demssew, Addo, Isaac Yeboah, Adnan, Mohammad, Sakilah Adnani, Qorinah Estiningtyas, Ahmad, Sajjad, Ahmadi, Ali, Ahmadi, Keivan, Ahmed, Ali, Ahmed, Ayman, Rashid, Tarik Ahmed, Al Hamad, Hanadi, Alahdab, Fares, Alemayehu, Astawus, Alif, Sheikh Mohammad, Aljunid, Syed Mohamed, Almustanyir, Sami, Altirkawi, Khalid A., Alvis-Guzman, Nelson, Dehkordi, Javad Aminian, Amir-Behghadami, Mehrdad, Ancuceanu, Robert, Andrei, Catalina Liliana, Andrei, Tudorel, Antony, Catherine M., Anyasodor, Anayochukwu Edward, Arabloo, Jalal, Arulappan, Judie, Ashraf, Tahira, Athari, Seyyed Shamsadin, Attia, Engi F., Ayele, Meshesha Tsegazeab, Azadnajafabad, Sina, Babu, Abraham Samuel, Bagherieh, Sara, Baltatu, Ovidiu Constantin, Banach, Maciej, Bardhan, Mainak, Barone-Adesi, Francesco, Barrow, Amadou, Basu, Saurav, Bayileyegn, Nebiyou Simegnew, Bensenor, Isabela M., Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhat, Ajay Nagesh, Bhattacharyya, Krittika, Bouaoud, Souad, Braithwaite, Dejana, Brauer, Michael, Butt, Muhammad Hammad, Butt, Zahid A., Calina, Daniela, Cámera, Luis Alberto, Chanie, Gashaw Sisay, Charalampous, Periklis, Chattu, Vijay Kumar, Chimed-Ochir, Odgerel, Chu, Dinh-Toi, Cohen, Aaron J., Cruz-Martins, Natália, Dadras, Omid, Darwesh, Aso Mohammad, Das, Saswati, Debela, Sisay Abebe, Delgado-Ortiz, Laura, Dereje, Diriba, Dianatinasab, Mostafa, Diao, Nancy, Diaz, Daniel, Digesa, Lankamo Ena, Dirirsa, Gebisa, Doku, Paul Narh, Dongarwar, Deepa, Douiri, Abdel, Dsouza, Haneil Larson, Eini, Ebrahim, Ekholuenetale, Michael, Ekundayo, Temitope Cyrus, Mustafa Elagali, Ahmed Elabbas, Elhadi, Muhammed, Enyew, Daniel Berhanie, Erkhembayar, Ryenchindorj, Etaee, Farshid, Fagbamigbe, Adeniyi Francis, Faro, Andre, Fatehizadeh, Ali, Fekadu, Ginenus, Filip, Irina, Fischer, Florian, Foroutan, Masoud, Franklin, Richard Charles, Gaal, Peter Andras, Gaihre, Santosh, Gaipov, Abduzhappar, Gebrehiwot, Mesfin, Gerema, Urge, Getachew, Motuma Erena, Getachew, Tamiru, Ghafourifard, Mansour, Ghanbari, Reza, Ghashghaee, Ahmad, Gholami, Ali, Gil, Artyom Urievich, Golechha, Mahaveer, Goleij, Pouya, Golinelli, Davide, Guadie, Habtamu Alganeh, Gupta, Bhawna, Gupta, Sapna, Gupta, Veer Bala, Gupta, Vivek Kumar, Hadei, Mostafa, Halwani, Rabih, Hanif, Asif, Hargono, Arief, Harorani, Mehdi, Hartono, Risky Kusuma, Hasani, Hamidreza, Hashi, Abdiwahab, Hay, Simon I., Heidari, Mohammad, Hellemons, Merel E., Herteliu, Claudiu, Holla, Ramesh, Horita, Nobuyuki, Hoseini, Mohammad, Hosseinzadeh, Mehdi, Huang, Junjie, Hussain, Salman, Hwang, Bing-Fang, Iavicoli, Ivo, Ibitoye, Segun Emmanuel, Ibrahim, Sufyan, Ilesanmi, Olayinka Stephen, Ilic, Irena M., Ilic, Milena D., Immurana, Mustapha, Ismail, Nahlah Elkudssiah, Merin J, Linda, Jakovljevic, Mihajlo, Jamshidi, Elham, Janodia, Manthan Dilipkumar, Javaheri, Tahereh, Jayapal, Sathish Kumar, Jayaram, Shubha, Jha, Ravi Prakash, Johnson, Olatunji, Joo, Tamas, Joseph, Nitin, Jozwiak, Jacek Jerzy, K, Vaishali, Kaambwa, Billingsley, Kabir, Zubair, Kalankesh, Laleh R., Kalhor, Rohollah, Kandel, Himal, Karanth, Shama D., Karaye, Ibraheem M., Kassa, Bekalu Getnet, Kassie, Gizat M., Keikavoosi-Arani, Leila, Keykhaei, Mohammad, Khajuria, Himanshu, Khan, Imteyaz A., Khan, Moien A.B., Khan, Yusra H., Khreis, Haneen, Kim, Min Seo, Kisa, Adnan, Kisa, Sezer, Knibbs, Luke D., Kolkhir, Pavel, Komaki, Somayeh, Kompani, Farzad, Koohestani, Hamid Reza, Koolivand, Ali, Korzh, Oleksii, Koyanagi, Ai, Krishan, Kewal, Krohn, Kris J., Kumar, Naveen, Kumar, Nithin, Kurmi, Om P., Kuttikkattu, Ambily, La Vecchia, Carlo, Lám, Judit, Lan, Qing, Lasrado, Savita, Latief, Kamaluddin, Lauriola, Paolo, Lee, Sang-woong, Lee, Yo Han, Legesse, Samson Mideksa, Lenzi, Jacopo, Li, Ming-Chieh, Lin, Ro-Ting, Liu, Gang, Liu, Wei, Lo, Chun-Han, Lorenzovici, László, Lu, Yifei, Mahalingam, Soundarya, Mahmoudi, Elham, Mahotra, Narayan B., Malekpour, Mohammad-Reza, Malik, Ahmad Azam, Mallhi, Tauqeer Hussain, Malta, Deborah Carvalho, Mansouri, Borhan, Mathews, Elezebeth, Maulud, Sazan Qadir, Mechili, Enkeleint A., Nasab, Entezar Mehrabi, Menezes, Ritesh G., Mengistu, Dechasa Adare, Mentis, Alexios-Fotios, Meshkat, Mahboobeh, Mestrovic, Tomislav, Micheletti Gomide Nogueira de Sá, Ana Carolina, Mirrakhimov, Erkin M., Misganaw, Awoke, Mithra, Prasanna, Moghadasi, Javad, Mohammadi, Esmaeil, Mohammadi, Mokhtar, Mohammadshahi, Marita, Mohammed, Shafiu, Mohan, Syam, Moka, Nagabhishek, Monasta, Lorenzo, Moni, Mohammad Ali, Moniruzzaman, Md, Montazeri, Fateme, Moradi, Maryam, Mostafavi, Ebrahim, Mpundu-Kaambwa, Christine, Murillo-Zamora, Efrén, Murray, Christopher J.L., Nair, Tapas Sadasivan, Nangia, Vinay, Swamy, Sreenivas Narasimha, Narayana, Aparna Ichalangod, Natto, Zuhair S., Nayak, Biswa Prakash, Negash, Wogene Wogene, Nena, Evangelia, Kandel, Sandhya Neupane, Niazi, Robina Khan, Nogueira de Sá, Antonio Tolentino, Nowroozi, Ali, Nzoputam, Chimezie Igwegbe, Nzoputam, Ogochukwu Janet, Oancea, Bogdan, Obaidur, Rahman Md, Odukoya, Oluwakemi Ololade, Okati-Aliabad, Hassan, Okekunle, Akinkunmi Paul, Okonji, Osaretin Christabel, Olagunju, Andrew T., Bali, Ahmed Omar, Ostojic, Sergej M., A, Mahesh P., Padron-Monedero, Alicia, Padubidri, Jagadish Rao, Pahlevan Fallahy, Mohammad Taha, Palicz, Tamás, Pana, Adrian, Park, Eun-Kee, Patel, Jay, Paudel, Rajan, Paudel, Uttam, Pedersini, Paolo, Pereira, Marcos, Pereira, Renato B., Petcu, Ionela-Roxana, Pirestani, Majid, Postma, Maarten J., Prashant, Akila, Rabiee, Mohammad, Radfar, Amir, Rafiei, Sima, Rahim, Fakher, Ur Rahman, Mohammad Hifz, Rahman, Mosiur, Rahman, Muhammad Aziz, Rahmani, Amir Masoud, Rahmani, Shayan, Rahmanian, Vahid, Rajput, Prashant, Rana, Juwel, Rao, Chythra R., Rao, Sowmya J., Rashedi, Sina, Rashidi, Mohammad-Mahdi, Ratan, Zubair Ahmed, Rawaf, David Laith, Rawaf, Salman, Rawal, Lal, Rawassizadeh, Reza, Razeghinia, Mohammad Sadegh, Mohamed Redwan, Elrashdy Moustafa, Rezaei, Maryam, Rezaei, Nazila, Rezaei, Nima, Rezaeian, Mohsen, Rodrigues, Mónica, Buendia Rodriguez, Jefferson Antonio, Roever, Leonardo, Rojas-Rueda, David, Rudd, Kristina E., Saad, Aly M.A., Sabour, Siamak, Saddik, Basema, Sadeghi, Erfan, Sadeghi, Masoumeh, Saeed, Umar, Sahebazzamani, Maryam, Sahebkar, Amirhossein, Sahoo, Harihar, Sajid, Mirza Rizwan, Sakhamuri, Sateesh, Salehi, Sana, Samy, Abdallah M., Santric-Milicevic, Milena M., Sao Jose, Bruno Piassi, Sathian, Brijesh, Satpathy, Maheswar, Saya, Ganesh Kumar, Senthilkumaran, Subramanian, Seylani, Allen, Shahabi, Saeed, Shaikh, Masood Ali, Shanawaz, Mohd, Shannawaz, Mohammed, Sheikhi, Rahim Ali, Shekhar, Shashank, Sibhat, Migbar Mekonnen, Simpson, Colin R., Singh, Jasvinder A., Singh, Paramdeep, Singh, Surjit, Skryabin, Valentin Yurievich, Skryabina, Anna Aleksandrovna, Soltani-Zangbar, Mohammad Sadegh, Song, Suhang, Soyiri, Ireneous N., Steiropoulos, Paschalis, Stockfelt, Leo, Sun, Jing, Takahashi, Ken, Talaat, Iman M., Tan, Ker-Kan, Tat, Nathan Y., Tat, Vivian Y., Taye, Birhan Tsegaw, Thangaraju, Pugazhenthan, Thapar, Rekha, Thienemann, Friedrich, Tiyuri, Amir, Ngoc Tran, Mai Thi, Tripathy, Jaya Prasad, Car, Lorainne Tudor, Tusa, Biruk Shalmeno, Ullah, Irfan, Ullah, Sana, Vacante, Marco, Valdez, Pascual R., Valizadeh, Rohollah, van Boven, Job F.M., Vasankari, Tommi Juhani, Vaziri, Siavash, Violante, Francesco S., Vo, Bay, Wang, Ning, Wei, Melissa Y., Westerman, Ronny, Wickramasinghe, Nuwan Darshana, Xu, Suowen, Xu, Xiaoyue, Yadav, Lalit, Yismaw, Yazachew, Yon, Dong Keon, Yonemoto, Naohiro, Yu, Chuanhua, Yu, Yong, Yunusa, Ismaeel, Zahir, Mazyar, Zangiabadian, Moein, Zareshahrabadi, Zahra, Zarrintan, Armin, Zastrozhin, Mikhail Sergeevich, Zegeye, Zelalem Banjaw, Zhang, Yunquan, Naghavi, Mohsen, Larijani, Bagher, and Farzadfar, Farshad
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- 2023
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20. The Benefit of Complete Response to Treatment in Patients With Chronic Spontaneous Urticaria—CURE Results
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Kolkhir, Pavel, Laires, Pedro A., Salameh, Pascale, Asero, Riccardo, Bizjak, Mojca, Košnik, Mitja, Dissemond, Joachim, van Doorn, Martijn, Hawro, Tomasz, Kasperska-Zajac, Alicja, Zajac, Magdalena, Kocatürk, Emek, Peter, Jonny, Parisi, Claudio A.S., Ritchie, Carla A., Kulthanan, Kanokvalai, Tuchinda, Papapit, Fomina, Daria, Kovalkova, Elena, Khoshkhui, Maryam, Kouzegaran, Samaneh, Papapostolou, Niki, Du-Thanh, Aurélie, Kamegashira, Akiko, Meshkova, Raisa, Vitchuk, Alexander, Bauer, Andrea, Grattan, Clive, Staubach, Petra, Bouillet, Laurence, Giménez-Arnau, Ana M., Maurer, Marcus, and Weller, Karsten
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- 2023
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21. In Urticarial Vasculitis, Long Disease Duration, High Symptom Burden, and High Need for Therapy Are Linked to Low Patient-Reported Quality of Life
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Bonnekoh, Hanna, Jelden-Thurm, Jannis, Butze, Monique, Krause, Karoline, Maurer, Marcus, and Kolkhir, Pavel
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- 2022
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22. The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019
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Tran, Khanh Bao, Lang, Justin J, Compton, Kelly, Xu, Rixing, Acheson, Alistair R, Henrikson, Hannah Jacqueline, Kocarnik, Jonathan M, Penberthy, Louise, Aali, Amirali, Abbas, Qamar, Abbasi, Behzad, Abbasi-Kangevari, Mohsen, Abbasi-Kangevari, Zeinab, Abbastabar, Hedayat, Abdelmasseh, Michael, Abd-Elsalam, Sherief, Abdelwahab, Ahmed Abdelwahab, Abdoli, Gholamreza, Abdulkadir, Hanan Abdulkadir, Abedi, Aidin, Abegaz, Kedir Hussein, Abidi, Hassan, Aboagye, Richard Gyan, Abolhassani, Hassan, Absalan, Abdorrahim, Abtew, Yonas Derso, Abubaker Ali, Hiwa, Abu-Gharbieh, Eman, Achappa, Basavaprabhu, Acuna, Juan Manuel, Addison, Daniel, Addo, Isaac Yeboah, Adegboye, Oyelola A, Adesina, Miracle Ayomikun, Adnan, Mohammad, Adnani, Qorinah Estiningtyas Sakilah, Advani, Shailesh M, Afrin, Sumia, Afzal, Muhammad Sohail, Aggarwal, Manik, Ahinkorah, Bright Opoku, Ahmad, Araz Ramazan, Ahmad, Rizwan, Ahmad, Sajjad, Ahmad, Sohail, Ahmadi, Sepideh, Ahmed, Haroon, Ahmed, Luai A, Ahmed, Muktar Beshir, Ahmed Rashid, Tarik, Aiman, Wajeeha, Ajami, Marjan, Akalu, Gizachew Taddesse, Akbarzadeh-Khiavi, Mostafa, Aklilu, Addis, Akonde, Maxwell, Akunna, Chisom Joyqueenet, Al Hamad, Hanadi, Alahdab, Fares, Alanezi, Fahad Mashhour, Alanzi, Turki M, Alessy, Saleh Ali, Algammal, Abdelazeem M, Al-Hanawi, Mohammed Khaled, Alhassan, Robert Kaba, Ali, Beriwan Abdulqadir, Ali, Liaqat, Ali, Syed Shujait, Alimohamadi, Yousef, Alipour, Vahid, Aljunid, Syed Mohamed, Alkhayyat, Motasem, Al-Maweri, Sadeq Ali Ali, Almustanyir, Sami, Alonso, Nivaldo, Alqalyoobi, Shehabaldin, Al-Raddadi, Rajaa M, Al-Rifai, Rami H Hani, Al-Sabah, Salman Khalifah, Al-Tammemi, Ala'a B, Altawalah, Haya, Alvis-Guzman, Nelson, Amare, Firehiwot, Ameyaw, Edward Kwabena, Aminian Dehkordi, Javad Javad, Amirzade-Iranaq, Mohammad Hosein, Amu, Hubert, Amusa, Ganiyu Adeniyi, Ancuceanu, Robert, Anderson, Jason A, Animut, Yaregal Animut, Anoushiravani, Amir, Anoushirvani, Ali Arash, Ansari-Moghaddam, Alireza, Ansha, Mustafa Geleto, Antony, Benny, Antwi, Maxwell Hubert, Anwar, Sumadi Lukman, Anwer, Razique, Anyasodor, Anayochukwu Edward, Arabloo, Jalal, Arab-Zozani, Morteza, Aremu, Olatunde, Argaw, Ayele Mamo, Ariffin, Hany, Aripov, Timur, Arshad, Muhammad, Artaman, Al, Arulappan, Judie, Aruleba, Raphael Taiwo, Aryannejad, Armin, Asaad, Malke, Asemahagn, Mulusew A, Asemi, Zatollah, Asghari-Jafarabadi, Mohammad, Ashraf, Tahira, Assadi, Reza, Athar, Mohammad, Athari, Seyyed Shamsadin, Atout, Maha Moh'd Wahbi, Attia, Sameh, Aujayeb, Avinash, Ausloos, Marcel, Avila-Burgos, Leticia, Awedew, Atalel Fentahun, Awoke, Mamaru Ayenew, Awoke, Tewachew, Ayala Quintanilla, Beatriz Paulina, Ayana, Tegegn Mulatu, Ayen, Solomon Shitu, Azadi, Davood, Azadnajafabad, Sina, Azami-Aghdash, Saber, Azanaw, Melkalem Mamuye, Azangou-Khyavy, Mohammadreza, Azari Jafari, Amirhossein, Azizi, Hosein, Azzam, Ahmed Y Y, Babajani, Amirhesam, Badar, Muhammad, Badiye, Ashish D, Baghcheghi, Nayereh, Bagheri, Nader, Bagherieh, Sara, Bahadory, Saeed, Baig, Atif Amin, Baker, Jennifer L, Bakhtiari, Ahad, Bakshi, Ravleen Kaur, Banach, Maciej, Banerjee, Indrajit, Bardhan, Mainak, Barone-Adesi, Francesco, Barra, Fabio, Barrow, Amadou, Bashir, Nasir Z, Bashiri, Azadeh, Basu, Saurav, Batiha, Abdul-Monim Mohammad, Begum, Aeysha, Bekele, Alehegn Bekele, Belay, Alemayehu Sayih, Belete, Melaku Ashagrie, Belgaumi, Uzma Iqbal, Bell, Arielle Wilder, Belo, Luis, Benzian, Habib, Berhie, Alemshet Yirga, Bermudez, Amiel Nazer C, Bernabe, Eduardo, Bhagavathula, Akshaya Srikanth, Bhala, Neeraj, Bhandari, Bharti Bhandari, Bhardwaj, Nikha, Bhardwaj, Pankaj, Bhattacharyya, Krittika, Bhojaraja, Vijayalakshmi S, Bhuyan, Soumitra S, Bibi, Sadia, Bilchut, Awraris Hailu, Bintoro, Bagas Suryo, Biondi, Antonio, Birega, Mesfin Geremaw Birega, Birhan, Habitu Eshetu, Bjørge, Tone, Blyuss, Oleg, Bodicha, Belay Boda Abule, Bolla, Srinivasa Rao, Boloor, Archith, Bosetti, Cristina, Braithwaite, Dejana, Brauer, Michael, Brenner, Hermann, Briko, Andrey Nikolaevich, Briko, Nikolay 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- 2022
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23. Understanding human mast cells: lesson from therapies for allergic and non-allergic diseases
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Kolkhir, Pavel, Elieh-Ali-Komi, Daniel, Metz, Martin, Siebenhaar, Frank, and Maurer, Marcus
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- 2022
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24. Urticaria
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Kolkhir, Pavel, Giménez-Arnau, Ana M., Kulthanan, Kanokvalai, Peter, Jonny, Metz, Martin, and Maurer, Marcus
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- 2022
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25. An EU task force to assess the burden of rare diseases
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Kolkhir, Pavel, Grad, Diana Alecsandra, Charalampous, Periklis, Oliveira, Claudia Cruz, Mechili, Enkeleint A., Unim, Brigid, Pearce, David A., Maurer, Marcus, Devleesschauwer, Brecht, and Haagsma, Juanita
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- 2023
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26. Chronic Spontaneous Urticaria: A Review.
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Kolkhir, Pavel, Bonnekoh, Hanna, Metz, Martin, and Maurer, Marcus
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URTICARIA , *AUTOIMMUNE thyroiditis , *SKIN diseases , *SYMPTOMS , *OFF-label use (Drugs) , *METABOLIC syndrome - Abstract
Importance: Chronic spontaneous urticaria affects approximately 1% of the general population worldwide, including approximately 3 million people in the US, impairs patients' quality of life, and is associated with multiple comorbidities. Observations: Chronic spontaneous urticaria affects patients of any age but is most common in females aged 30 to 50 years. Diagnosis is based on clinical presentation, ie, spontaneously recurring wheals, angioedema, or both. Chronic spontaneous urticaria persists for more than 1 year in most patients (1 or repeated episodes) and may present with comorbidities including chronic inducible urticaria (>10%), autoimmune thyroiditis (approximately 20%), metabolic syndrome (6%-20%), and anxiety (10%-31%) and depression (7%-29%). Known autoimmune endotypes (subtypes of urticaria defined by distinct pathogenesis) of chronic spontaneous urticaria are mediated by mast cell–activating IgE and/or IgG autoantibodies (>50%). Approximately 40% of patients with chronic spontaneous urticaria have a Dermatology Life Quality Index of more than 10, corresponding to a very large or extremely large negative effect on quality of life. Second-generation H1 antihistamines are first-line treatment; partial or complete response, defined as a reduction in urticaria symptoms of greater than 50%, is observed in approximately 40% of patients. The 2022 international urticaria guideline recommends the monoclonal anti-IgE antibody omalizumab as second-line treatment for antihistamine-refractory chronic spontaneous urticaria. However, at least 30% of patients have an insufficient response to omalizumab, especially those with IgG-mediated autoimmune urticaria. Cyclosporine, used off-label, can improve symptoms in approximately 54% to 73% of patients, especially those with autoimmune chronic spontaneous urticaria and nonresponse to omalizumab, but has adverse effects such as kidney dysfunction and hypertension. Conclusions and Relevance: Chronic spontaneous urticaria is an inflammatory skin disease associated with medical and psychiatric comorbidities and impaired quality of life. Second-generation H1 antihistamines are first-line treatment, omalizumab is second-line treatment, and cyclosporine is third-line treatment for chronic spontaneous urticaria. This narrative review summarizes current evidence on the epidemiology, pathophysiology, diagnosis, and treatment of chronic spontaneous urticaria. [ABSTRACT FROM AUTHOR]
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- 2024
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27. A systematic review of studies that estimated the burden of chronic non-communicable rare diseases using disability-adjusted life years.
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Oliveira, Claudia Cruz, Charalampous, Periklis, Delaye, Julien, Grad, Diana Alecsandra, Kolkhir, Pavel, Mechili, Enkeleint A., Unim, Brigid, Devleesschauwer, Brecht, and Haagsma, Juanita A.
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NEUROLOGICAL disorders ,OCCUPATIONAL diseases ,DATA harmonization ,RARE diseases ,GREY literature ,MEDLINE - Abstract
Background: Initiatives aiming to assess the impact of rare diseases on population health might be hampered due to the complexity of disability-adjusted life years (DALYs) estimation. This study aimed to give insight into the epidemiological data sources and methodological approaches used in studies that estimated DALYs for chronic non-communicable rare diseases (CNCRD), and compare its results. Methods: A literature strategy was developed for peer-review search in Embase and Medline, and also performed on grey literature databases and population health and/or rare disease-focused websites. We included studies that determined the burden of CNCRD listed on the Orphanet's and/or the Genetic and Rare Diseases information center (GARD) websites. We excluded communicable and occupational diseases, rare cancers, and cost-effectiveness/benefit studies. Two researchers independently screened the identified records and extracted data from the final included studies. We used the Guidelines for Accurate and Transparent Health Estimates Reporting (GATHER) statement to assess the quality of reporting of the included studies. The data synthesis depicted the studies' characteristics, their distribution by geographic coverage and the group of disease(s) they focused on, the methods and data input sources used and estimated DALY per case. Results: In total, 533 titles were screened, and 18 studies were included. These studies covered 19 different CNCRDs, of which most fell in the disease category "Diseases of the nervous system". Diverse methodological approaches and data input sources were observed among burden of CNCRD studies. A wide range of DALY per case was observed across the different studies and diseases included. Conclusions: A low number of burden of CNCRD studies was observed and most estimates resulted from multi-country studies, underlining the importance of international cooperation to further CNCRD research. This study revealed a lack of epidemiological data and harmonization of methods which hampers comparisons across burden of CNCRD studies. [ABSTRACT FROM AUTHOR]
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- 2024
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28. Disease modification in chronic spontaneous urticaria.
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Maurer, Marcus, Kolkhir, Pavel, Pereira, Manuel P., Siebenhaar, Frank, Witte‐Händel, Ellen, Bergmann, Karl‐Christian, Bonnekoh, Hanna, Buttgereit, Thomas, Fluhr, Joachim W., Frischbutter, Stefan, Grekowitz, Eva Maria, Herzog, Leonie, Kiefer, Lea Alice, Krause, Karoline, Magerl, Markus, Muñoz, Melba, Neisinger, Sophia, Nojarov, Nicole, Prins, Samantha, and Pyatilova, Polina
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BRUTON tyrosine kinase , *DISEASE remission , *MAST cells , *GUT microbiome , *DISEASE progression , *URTICARIA - Abstract
Chronic spontaneous urticaria (CSU) is a debilitating, inflammatory skin condition characterized by infiltrating immune cells. Available treatments are limited to improving the signs and symptoms. There is an unmet need to develop therapies that target disease‐driving pathways upstream of mast cell activation to inhibit or delay the progression of CSU and associated comorbidities. Here, we aim to define disease modification due to a treatment intervention and criteria that disease‐modifying treatments (DMTs) must meet in CSU. We have defined disease modification in CSU as a favorable treatment‐induced change in the underlying pathophysiology and, therefore, the disease course, which is clinically beneficial and enduring. A DMT must fulfil the following criteria: (1) prevents or delays the progression of CSU, (2) induces long‐term, therapy‐free clinical remission, which is the sustained absence of CSU signs and symptoms without the need for treatment, and (3) affects the underlying mechanism of CSU, as demonstrated by an effect on disease‐driving signals and/or a biomarker. DMTs in CSU should slow disease progression, achieve long‐lasting disease remission, target disease‐driving mechanisms, reduce mast cell‐activating IgE autoantibodies, target cytokine profile polarization, and normalize the gut microbiome and barrier. Treating CSU at the immune system level could provide valuable alternatives to pharmacotherapy in CSU management. Specific DMTs in CSU are yet to be developed, but some show potential benefits, such as inhibitors of Bruton's Tyrosine Kinase, IL‐4 and IL‐13. Future therapies could prevent CSU signs and symptoms, achieve long‐term clinical benefits after discontinuing treatment, and prevent associated concomitant disorders. [ABSTRACT FROM AUTHOR]
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- 2024
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29. Chronic Spontaneous Urticaria and Comorbidities
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Kolkhir, Pavel, Maurer, Marcus, Zuberbier, Torsten, editor, Grattan, Clive, editor, and Maurer, Marcus, editor
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- 2021
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30. Usage prevalence of angioedema patient-reported outcome measures: results from the UCARE and ACARE PROMUSE study
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Cherrez-Ojeda, Ivan, primary, Bousquet, Jean, additional, Giménez-Arnau, Ana, additional, Godse, Kiran, additional, Krasowska, Dorota, additional, Bartosińska, Joanna, additional, Szczepanik-Kułak, Paulina, additional, Wawrzycki, Bartłomiej, additional, Kolkhir, Pavel, additional, Allenova, Anastasiia, additional, Allenov, Andrey, additional, Tkachenko, Sergey, additional, Teovska Mitrevska, Natasa, additional, Mijakoski, Dragan, additional, Stoleski, Sasho, additional, Kolacinska-Flont, Marta, additional, Kuprys-Lipinska, Izabela, additional, Molinska, Joanna, additional, Kasperska-Zając, Alicja, additional, Zajac, Magdalena, additional, Zamlynski, Mateusz, additional, Mihaltan, Florin, additional, Ulmeanu, Ruxandra, additional, Zalewska-Janowska, Anna, additional, Tomaszewska, Katarzyna, additional, Al-Ahmad, Mona, additional, Al-Nesf, Maryam Ali, additional, Ibrahim, Tayseer, additional, Aqel, Sami, additional, Pesqué, David, additional, Rodríguez-González, Mónica, additional, Wakida-Kuzunoki, Guillermo Hideo, additional, Ramon, German D., additional, Ramon, Gonzalo N., additional, Neisinger, Sophia, additional, Bonnekoh, Hanna, additional, Rukhadze, Maia, additional, Khoshkhui, Maryam, additional, Fomina, Daria, additional, Larenas-Linnemann, Désirée, additional, Košnik, Mitja, additional, Oztas Kara, Rabia, additional, Caballero López, Chrystopherson Gengyny, additional, Liu, Qiang, additional, Ivancevich, Juan Carlos, additional, Ensina, Luis Felipe, additional, Rosario, Nelson, additional, Kvedariene, Violeta, additional, Ben-Shoshan, Moshe, additional, Criado, Roberta Fachini Jardim, additional, Bauer, Andrea, additional, Cherrez, Annia, additional, Cherrez, Sofia, additional, Chong-Neto, Herberto, additional, Rojo-Gutierrez, Maria Isabel, additional, Rudenko, Michael, additional, Larco Sousa, José Ignacio, additional, Lesiak, Aleksandra, additional, Matos, Edgar, additional, Tinoco, Ivan, additional, Crespo Shijin, Carolina, additional, Hinostroza Logroño, Romina, additional, Sagñay, Juan C., additional, Faytong-Haro, Marco, additional, Robles-Velasco, Karla, additional, Zuberbier, Torsten, additional, and Maurer, Marcus, additional
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- 2024
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31. Non-Skin-Related Symptoms are Common in Chronic Spontaneous Urticaria and Linked to Active and Uncontrolled Disease: Results from CURE
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Pyatilova, Polina, primary, Hackler, Yana, additional, Aulenbacher, Felix, additional, Asero, Riccardo, additional, Bauer, Andrea, additional, Bizjak, Mojca, additional, Day, Cascia, additional, Dissemond, Joachim, additional, Du-Thanh, Aurélie, additional, Fomina, Daria, additional, Giménez-Arnau, Ana M., additional, Grattan, Clive, additional, Gregoriou, Stamatis, additional, Hawro, Tomasz, additional, Kasperska-Zajac, Alicja, additional, Khoshkhui, Maryam, additional, Kocatürk, Emek, additional, Kovalkova, Elena, additional, Kulthanan, Kanokvalai, additional, Kuznetsova, Elizaveta, additional, Makris, Michael, additional, Mukhina, Olga, additional, Pesqué, David, additional, Peter, Jonny, additional, Salameh, Pascale, additional, Siebenhaar, Frank, additional, Sikora, Agnieszka, additional, Staubach, Petra, additional, Tuchinda, Papapit, additional, Zamłyński, Mateusz, additional, Weller, Karsten, additional, Maurer, Marcus, additional, and Kolkhir, Pavel, additional
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- 2024
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32. Autoimmune Chronic Spontaneous Urticaria Detection with IgG Anti-TPO and Total IgE
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Kolkhir, Pavel, Kovalkova, Elena, Chernov, Anton, Danilycheva, Inna, Krause, Karoline, Sauer, Merle, Shulzhenko, Andrey, Fomina, Daria, and Maurer, Marcus
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- 2021
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33. The Diagnostic Workup in Chronic Spontaneous Urticaria—What to Test and Why
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Metz, Martin, Altrichter, Sabine, Buttgereit, Thomas, Fluhr, Joachim W., Fok, Jie Shen, Hawro, Tomasz, Jiao, Qingqing, Kolkhir, Pavel, Krause, Karoline, Magerl, Markus, Pyatilova, Polina, Siebenhaar, Frank, Su, Huichun, Terhorst-Molawi, Dorothea, Weller, Karsten, Xiang, Yi-Kui, and Maurer, Marcus
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- 2021
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34. Chronic Urticaria
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Kolkhir, Pavel, primary, Muñoz, Melba, additional, Terhorst-Molawi, Dorothea, additional, Church, Martin K., additional, and Maurer, Marcus, additional
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- 2022
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35. The Pharmacology of Antihistamines
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Church, Martin K., primary, Frischbutter, Stefan, additional, Kolkhir, Pavel, additional, and Maurer, Marcus, additional
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- 2022
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36. The role of eosinophils in chronic spontaneous urticaria
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Altrichter, Sabine, Frischbutter, Stefan, Fok, Jie Shen, Kolkhir, Pavel, Jiao, Qingqing, Skov, Per Stahl, Metz, Martin, Church, Martin K., and Maurer, Marcus
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- 2020
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37. Management of urticarial vasculitis: A worldwide physician perspective
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Kolkhir, Pavel, Bonnekoh, Hanna, Kocatürk, Emek, Hide, Michihiro, Metz, Martin, Sánchez-Borges, Mario, Krause, Karoline, and Maurer, Marcus
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- 2020
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38. Eosinopenia, in Chronic Spontaneous Urticaria, Is Associated with High Disease Activity, Autoimmunity, and Poor Response to Treatment
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Kolkhir, Pavel, Church, Martin K., Altrichter, Sabine, Skov, Per Stahl, Hawro, Tomasz, Frischbutter, Stefan, Metz, Martin, and Maurer, Marcus
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- 2020
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39. How to Treat Patients with Chronic Spontaneous Urticaria with Omalizumab: Questions and Answers
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Türk, Murat, Carneiro-Leão, Leonor, Kolkhir, Pavel, Bonnekoh, Hanna, Buttgereit, Thomas, and Maurer, Marcus
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- 2020
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40. Enhancing Angioedema Patient Care: Unveiling Underutilization and Barriers in the Implementation of Patient-Reported Outcome Measurements
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Ojeda, Ivan Cherrez, primary, Maurer, Marcus, additional, Bousquet, Jean, additional, Gimenez-Arnau, Ana, additional, Godse, Kiran, additional, Krasowska, Dorota, additional, Robles-Velasco, Karla, additional, Kolkhir, Pavel, additional, Tkachenko, Sergey, additional, Mitrevska, Natasa Teovska, additional, Kolacinska-Flont, Marta, additional, Kuprys-Lipinska, Izabela, additional, Molinska, Joanna, additional, Kasperska-Zajac, Alicja, additional, Zajac, Magdalena, additional, Zamlynski, Mateusz, additional, Mihaltan, Florin, additional, Zalewska-Janowska, Anna, additional, Tomaszewska, Katarzyna, additional, Al-Ahmad, Mona, additional, Al-Nesf, Maryam Ali, additional, Ibrahim, Tayseer, additional, Pesqué, David, additional, Rodriguez-Gonzalez, Monica, additional, Wakida-Kuzunoki, Guillermo Hideo, additional, Ramon, German, additional, Ramon, Gonzalo, additional, Neisinger, Sophia, additional, Bonnekoh, Hanna, additional, Rukhadze, Maia, additional, Ulmeanu, Ruxandra, additional, Khoshkhui, Maryam, additional, Faytong-Haro, Marco, additional, Fomina, Daria, additional, Rudenko, Michael, additional, Ben-shoshan, Moshe, additional, Linnemann, Desiree Larenas, additional, Kvedariene, Violeta, additional, Košnik, Mitja, additional, Zuberbier, Torsten, additional, Kara, Rabia Oztas, additional, Caballero López, Chrystopherson Gengyny, additional, Criado, Roberta, additional, Liu, Qiang, additional, and Rosario, Nelson, additional
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- 2024
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41. Treatment of urticarial vasculitis: A systematic review
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Kolkhir, Pavel, Grakhova, Maria, Bonnekoh, Hanna, Krause, Karoline, and Maurer, Marcus
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- 2019
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42. In the skin lesions of patients with mycosis fungoides, the number of MRGPRX2-expressing cells is increased and correlates with mast cell numbers
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Hu, Man, primary, Pyatilova, Polina, additional, Altrichter, Sabine, additional, Sheng, Caibin, additional, Liu, Nian, additional, Terhorst-Molawi, Dorothea, additional, Lohse, Katharina, additional, Ginter, Katharina, additional, Puhl, Viktoria, additional, Maurer, Marcus, additional, Metz, Martin, additional, and Kolkhir, Pavel, additional
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- 2023
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43. Differential diagnosis between urticarial vasculitis and chronic spontaneous urticaria: An international Delphi survey
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Krause, Karoline, primary, Bonnekoh, Hanna, additional, Jelden‐Thurm, Jannis, additional, Asero, Riccardo, additional, Gimenez‐Arnau, Ana Maria, additional, Cardoso, José C., additional, Grattan, Clive, additional, Kocatürk, Emek, additional, Lippert, Undine, additional, Maurer, Marcus, additional, Metz, Martin, additional, Staubach, Petra, additional, Goncalo, Margarida, additional, and Kolkhir, Pavel, additional
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- 2023
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44. Mentoring as the cornerstone of continued education in Allergy and Clinical Immunology: 10th anniversary of the EAACI mentorship program
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Giovannini, Mattia, primary, Beken, Burcin, additional, Agache, Ioana, additional, Akdis, Cezmi A., additional, Carvalho, Daniela, additional, Chivato, Tomas, additional, Comberiati, Pasquale, additional, De las Vecillas, Leticia, additional, Eguiluz‐Gracia, Ibon, additional, Heffler, Enrico, additional, Jutel, Marek, additional, Eyice Karabacak, Deniz, additional, Kolkhir, Pavel, additional, Moya, Beatriz, additional, Ollert, Markus, additional, O'Neil, Serena, additional, Santos, Alexandra F., additional, Schwarze, Jurgen, additional, Skevaki, Chrysanthi, additional, Sokolowska, Milena, additional, Tsilochristou, Olympia, additional, van Wijk, Roy Gerth, additional, del Giacco, Stefano, additional, and Riggioni, Carmen, additional
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- 2023
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45. Management of chronic spontaneous urticaria: a worldwide perspective
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Kolkhir, Pavel, Pogorelov, Dmitry, Darlenski, Razvigor, Caminati, Marco, Tanno, Luciana Kase, Le Pham, Duy, Gonzalez-Estrada, Alexei, Antolín-Amérigo, Darío, Dimov, Ves, Weller, Karsten, Sánchez-Borges, Mario, Ansotegui, Ignacio, and Maurer, Marcus
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- 2018
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46. Mast cell silencing: A novel therapeutic approach for urticaria and other mast cell‐mediated diseases
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Metz, Martin, primary, Kolkhir, Pavel, additional, Altrichter, Sabine, additional, Siebenhaar, Frank, additional, Levi‐Schaffer, Francesca, additional, Youngblood, Bradford A., additional, Church, Martin K., additional, and Maurer, Marcus, additional
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- 2023
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47. The Crucial Role of IgE as a Predictor of Treatment Response to Omalizumab in Chronic Spontaneous Urticaria
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Maurer, Marcus, primary, Kolkhir, Pavel, additional, Moñino-Romero, Sherezade, additional, and Metz, Martin, additional
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- 2023
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48. How Infection and Vaccination Are Linked to Acute and Chronic Urticaria: A Special Focus on COVID-19
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Kocatürk, Emek, primary, Muñoz, Melba, additional, Elieh-Ali-Komi, Daniel, additional, Criado, Paulo Ricardo, additional, Peter, Jonny, additional, Kolkhir, Pavel, additional, Can, Pelin, additional, Wedi, Bettina, additional, Rudenko, Michael, additional, Gotua, Maia, additional, Ensina, Luis Felipe, additional, Grattan, Clive, additional, and Maurer, Marcus, additional
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- 2023
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49. In chronic spontaneous urticaria soluble FcεRI is elevated and linked to atopy and chronic inducible urticaria
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Moñino‐Romero, Sherezade, primary, Kolkhir, Pavel, additional, Szépfalusi, Zsolt, additional, Schoepke, Nicole, additional, Metz, Martin, additional, Asero, Riccardo, additional, Ferrer, Marta, additional, Gimenez‐Arnau, Ana, additional, Grattan, Clive E. H., additional, Jakob, Thilo, additional, Konstantinou, George N., additional, Raap, Ulrike, additional, Staubach, Petra, additional, Zhang, Ke, additional, Bindslev‐Jensen, Carsten, additional, Daschner, Alvaro, additional, Kinaciyan, Tamar, additional, Makris, Michael, additional, Marrouche, Nadine, additional, Schmid‐Grendelmeier, Peter, additional, Sussman, Gordon, additional, Toubi, Elias, additional, Maurer, Marcus, additional, and Altrichter, Sabine, additional
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- 2023
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50. Mast cell silencing: A novel therapeutic approach for urticaria and other mast cell‐mediated diseases.
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Metz, Martin, Kolkhir, Pavel, Altrichter, Sabine, Siebenhaar, Frank, Levi‐Schaffer, Francesca, Youngblood, Bradford A., Church, Martin K., and Maurer, Marcus
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MAST cells , *THERAPEUTICS , *URTICARIA , *MONOCLONAL antibodies , *CELLULAR signal transduction , *TRYPTASE - Abstract
Chronic urticaria (CU) is a mast cell (MC)‐dependent disease with limited therapeutic options. Current management strategies are directed at inhibiting IgE‐mediated activation of MCs and antagonizing effects of released mediators. Due to the complexity and heterogeneity of CU and other MC diseases and mechanisms of MC activation—including multiple activating receptors and ligands, diverse signaling pathways, and a menagerie of mediators—strategies of MC depletion or MC silencing (i.e., inhibition of MC activation via binding of inhibitory receptors) have been developed to overcome limitations of singularly targeted agents. MC silencers, such as agonist monoclonal antibodies that engage inhibitory receptors (e.g., sialic acid‐binding immunoglobulin‐like lectin8 ‐[Siglec‐8] [lirentelimab/AK002], Siglec‐6 [AK006], and CD200R [LY3454738]), have reached preclinical and clinical stages of development. In this review, we (1) describe the role of MCs in the pathogenesis of CU, highlighting similarities with other MC diseases in disease mechanisms and response to treatment; (2) explore current therapeutic strategies, categorized by nonspecific immunosuppression, targeted inhibition of MC activation or mediators, and targeted modulation of MC activity; and (3) introduce the concept of MC silencing as an emerging strategy that could selectively block activation of MCs without eliciting or exacerbating on‐ or off‐target, immunosuppressive adverse effects. [ABSTRACT FROM AUTHOR]
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- 2024
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