479 results on '"Kamada, Haruhiko"'
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2. Development of a 1:1-binding biparatopic anti-TNFR2 antagonist by reducing signaling activity through epitope selection
3. Bivalent structure of a TNFR2-selective and agonistic TNF-α mutein Fc-fusion protein enhances the expansion activity of regulatory T cells
4. Synthesis of multivalent fatty acid-conjugated antisense oligonucleotides: Cell internalization, physical properties, and in vitro and in vivo activities
5. COVID-19 cynomolgus macaque model reflecting human COVID-19 pathological conditions
6. Synthesis and physical and biological properties of 1,3-diaza-2-oxophenoxazine-conjugated oligonucleotides
7. Discovery of anti-SARS-CoV-2 S2 protein antibody CV804 with broad-spectrum reactivity with various beta coronaviruses and analysis of its pharmacological properties in vitro and in vivo.
8. Identification of biomarkers of chronic kidney disease among kidney-derived proteins
9. Discovery of anti-SARS-CoV-2 S2 protein antibody CV804 with broad-spectrum reactivity with various beta coronaviruses and analysis of its pharmacological properties in vitro and in vivo
10. ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury
11. Production of IgG1-based bispecific antibody without extra cysteine residue via intein-mediated protein trans-splicing
12. Identification of a novel target of sulforaphane: Sulforaphane binds to acyl-protein thioesterase 2 (APT2) and attenuates its palmitoylation
13. An immunocytokine consisting of a TNFR2 agonist and TNFR2 scFv enhances the expansion of regulatory T cells through TNFR2 clustering
14. Anti-PD-1 antibodies recognizing the membrane-proximal region are agonists that can stimulate immunosuppressive activity of PD-1
15. Development of a 1:1-binding biparatopic anti-TNFR2 antagonist by reducing signaling activity through epitope selection
16. A Proximity‐Induced Fluorogenic Reaction Triggered by Antibody–Antigen Interactions with Adjacent Epitopes
17. Anti–PD-1 antibodies recognizing the membrane-proximal region are PD-1 agonists that can down-regulate inflammatory diseases
18. Identification of New Candidates as Mucosal Vaccine Adjuvant in TNF Family Cytokines
19. Anti-inflammatory Effects of a Novel TNFR1-Selective Antagonistic TNF Mutant on Established Murine Collagen-Induced Arthritis
20. Ephrin receptor A10 is a promising drug target potentially useful for breast cancers including triple negative breast cancers
21. A Proximity‐Induced Fluorogenic Reaction Triggered by Antibody–Antigen Interactions with Adjacent Epitopes.
22. Antibodies against adenovirus fiber and penton base proteins inhibit adenovirus vector-mediated transduction in the liver following systemic administration
23. Additional file 1 of Identification of biomarkers of chronic kidney disease among kidney-derived proteins
24. Systemic distribution, nuclear entry and cytotoxicity of amorphous nanosilica following topical application
25. Fine tuning of receptor-selectivity for tumor necrosis factor-α using a phage display system with one-step competitive panning
26. Development of an antibody proteomics system using a phage antibody library for efficient screening of biomarker proteins
27. Acute phase proteins as biomarkers for predicting the exposure and toxicity of nanomaterials
28. Therapeutic effect of PEGylated TNFR1-selective antagonistic mutant TNF in experimental autoimmune encephalomyelitis mice
29. Establishment of SARS-CoV-2 respiratory tract infection model in CAG promoter-driven hACE2 transgenic mice
30. Therapeutic effects of angiotensin converting enzyme 2 (ACE2) enzyme activity on acute lung injury in COVID-19
31. Size and surface modification of amorphous silica particles determine their effects on the activity of human CYP3A4 in vitro
32. Intestinal absorption and biological effects of orally administered amorphous silica particles
33. Evaluation of silica nanoparticle binding to major human blood proteins
34. In vivo biotinylation of the vasculature in B-cell lymphoma identifies BST-2 as a target for antibody-based therapy
35. Potential adjuvant effect of intranasal urban aerosols in mice through induction of dendritic cell maturation
36. Highly susceptible SARS-CoV-2 model in CAG promoter–driven hACE2-transgenic mice
37. Identification and evaluation of metastasis-related proteins, oxysterol binding protein-like 5 and calumenin, in lung tumors
38. The augmentation of intracellular delivery of peptide therapeutics by artificial protein transduction domains
39. The treatment of established murine collagen-induced arthritis with a TNFR1-selective antagonistic mutant TNF
40. The use of a mutant TNF-α as a vaccine adjuvant for the induction of mucosal immune responses
41. ACE2-like carboxypeptidase B38-CAP protects from SARS-CoV-2-induced lung injury
42. Production of IgG1-based bispecific antibody without extra cysteine residue via intein-mediated protein trans-splicing.
43. Hemopexin as biomarkers for analyzing the biological responses associated with exposure to silica nanoparticles
44. Effect of surface properties of silica nanoparticles on their cytotoxicity and cellular distribution in murine macrophages
45. Promotion of allergic immune responses by intranasally-administrated nanosilica particles in mice
46. Effect of amorphous silica nanoparticles on in vitro RANKL-induced osteoclast differentiation in murine macrophages
47. The therapeutic effect of TNFR1-selective antagonistic mutant TNF-α in murine hepatitis models
48. Carbon Nanotubes Elicit DNA Damage and Inflammatory Response Relative to Their Size and Shape
49. Characterization of a TNFR2-Selective Agonistic TNF-α Mutant and Its Derivatives as an Optimal Regulatory T Cell Expander
50. Suppression of SARS-CoV-2-induced lung injury by ACE2-like carboxypeptidase B38-CAP in COVID-19 mouse model
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