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2. [Spectrophotometric determination of methaqualone in biologic material].

Author

Kerde C

Subjects
Humans, Methaqualone blood, Methaqualone urine, Methods, Spectrophotometry, Ultraviolet, Methaqualone analysis
Abstract

A rapid and simple spectrophotometric procedure for the determination of 2-methyl-3-o-tolyl-4(3H)-quinazolinone (methaqualone) in biological material is described. After extraction of the specimen with chloroform and washing with 0.5 N sodium hydroxide and 0.5 N sulfuric acid methaqualone is extracted with 5 ml 50% sulfuric acid and read in a spectrophotometer at 234 nm. The procedure is suitable to determine serum levels of methaqualone after a therapeutic dose.

Published
1975

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