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Background Tooth sensitivity commonly occurs during and immediately after dental bleaching. The authors conducted a trial to compare tooth sensitivity after in-office bleaching after the use of either a topical dipyrone or placebo gel. Methods A split-mouth, triple-blind, randomized, multicenter clinical trial was conducted among 120 healthy adults having teeth that were shade A2 or darker. The facial tooth surfaces of the right or left sides of the maxillary arch of each patient were randomly assigned to receive either topical dipyrone or placebo gel before 2 in-office bleaching sessions (35% hydrogen peroxide) separated by 2 weeks. Visual analog and numerical rating scales were used to record tooth sensitivity during and up to 48 hours after bleaching. Tooth color change from baseline to 1 month after bleaching was measured with shade guide and spectrophotometer measures. The primary outcome variable was absolute risk of tooth sensitivity. An intention-to-treat analysis was used to analyze data from all patients who were randomly assigned to receive the dipyrone and placebo gels. Results No statically significant difference was found in the absolute risk of tooth sensitivity between the dipyrone and placebo gels (83% and 90%, respectively, P = .09; relative risk, 0.92; 95% confidence interval, 0.8 to 1.0). A whitening effect was observed in both groups with no statistically significant difference ( P > .05) between them. No adverse effects were observed. Conclusion Topical use of dipyrone gel before tooth bleaching, at the levels used in this study, did not reduce the risk or intensity of bleaching-induced tooth sensitivity. Practical Implications Topical application of dipyrone gel does not reduce bleaching-induced tooth sensitivity.

CAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior O clareamento dental é um procedimento para melhorar a estética do sorriso do paciente. O presente estudo teve como objetivo avaliar a eficácia e o impacto na auto percepção estética e nos fatores psicossociais da técnica combinada de clareamento dental em pacientes de diferentes faixas etárias. Este ensaio clínico triplo-cego, paralelo a dois grupos, foi realizado com 56 pacientes saudáveis. Todos os pacientes receberam o mesmo tratamento de clareamento combinado (38% de peróxido de hidrogênio no consultório e 20% de peróxido de carbamida em casa). Foram avaliados, o risco de sensibilidade dentária, mudança de cor utilizando escalas visuais e qualidade de vida relacionada à saúde bucal (OHRQoL) atribuído à estética dentária, utilizando a Escala de Estética Orofacial (OES) e o Questionário de Impacto Psicossocial do Estética Dental (PIDAQ). Como resultado obtivemos que o clareamento de consultório gerou maior sensibilidade e mudança de cor mais efetiva nos pacientes mais jovens. Após a técnica combinada, ambos os grupos de pacientes apresentaram alterações de cor semelhantes e risco de sensibilidade dentária, independentemente da idade. Ambos os grupos tiveram maior nível de satisfação após a técnica de clareamento combinada e os pacientes mais jovens apresentaram maior satisfação do que os mais velhos (p

Tooth sensitivity commonly occurs during and immediately after dental bleaching. The authors conducted a trial to compare tooth sensitivity after in-office bleaching after the use of either a topical dipyrone or placebo gel.A split-mouth, triple-blind, randomized, multicenter clinical trial was conducted among 120 healthy adults having teeth that were shade A2 or darker. The facial tooth surfaces of the right or left sides of the maxillary arch of each patient were randomly assigned to receive either topical dipyrone or placebo gel before 2 in-office bleaching sessions (35% hydrogen peroxide) separated by 2 weeks. Visual analog and numerical rating scales were used to record tooth sensitivity during and up to 48 hours after bleaching. Tooth color change from baseline to 1 month after bleaching was measured with shade guide and spectrophotometer measures. The primary outcome variable was absolute risk of tooth sensitivity. An intention-to-treat analysis was used to analyze data from all patients who were randomly assigned to receive the dipyrone and placebo gels.No statically significant difference was found in the absolute risk of tooth sensitivity between the dipyrone and placebo gels (83% and 90%, respectively, P = .09; relative risk, 0.92; 95% confidence interval, 0.8 to 1.0). A whitening effect was observed in both groups with no statistically significant difference (P.05) between them. No adverse effects were observed.Topical use of dipyrone gel before tooth bleaching, at the levels used in this study, did not reduce the risk or intensity of bleaching-induced tooth sensitivity.Topical application of dipyrone gel does not reduce bleaching-induced tooth sensitivity.