1,724 results on '"Hengstler, Jan G."'
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2. Commentary of the SKLM to the EFSA opinion on risk assessment of N-nitrosamines in food
3. Role of albumin in the metabolism and excretion of ochratoxin A
4. Acetaminophen overdose causes a breach of the blood–bile barrier in mice but not in rats
5. Integrated data from intravital imaging and HPLC–MS/MS analysis reveal large interspecies differences in AFB1 metabolism in mice and rats
6. Correction: Commentary of the SKLM to the EFSA opinion on risk assessment of N-nitrosamines in food
7. Basal MET phosphorylation is an indicator of hepatocyte dysregulation in liver disease
8. Basic concepts of mixture toxicity and relevance for risk evaluation and regulation
9. PFASs–restriction proposal commentary on ECHA’s Annex XV restriction report, proposal for a restriction, March 2023
10. Comparative metabolism of aflatoxin B1 in mouse, rat and human primary hepatocytes using HPLC–MS/MS
11. Guidance for statistical design and analysis of toxicological dose–response experiments, based on a comprehensive literature review
12. Transcriptome-based prediction of drugs, inhibiting cardiomyogenesis in human induced pluripotent stem cells
13. Alterations in the hepatocyte epigenetic landscape in steatosis
14. Inhibiting the glycerophosphodiesterase EDI3 in ER-HER2+ breast cancer cells resistant to HER2-targeted therapy reduces viability and tumour growth
15. Proteome analysis of monocytes implicates altered mitochondrial biology in adults reporting adverse childhood experiences
16. G × E interactions as a basis for toxicological uncertainty
17. PBTK modeling of the pyrrolizidine alkaloid retrorsine to predict liver toxicity in mouse and rat
18. The impact of physical fitness, social life, and cognitive functions on work ability in middle-aged and older adults
19. Inhibition of the renal apical sodium dependent bile acid transporter prevents cholemic nephropathy in mice with obstructive cholestasis
20. Induction of steatosis in primary human hepatocytes recapitulates key pathophysiological aspects of metabolic dysfunction-associated steatotic liver disease
21. Model predicts fundamental role of biomechanical control of cell cycle progression during liver regeneration after partial hepatectomy
22. Tolerance of repeated toxic injuries of murine livers is associated with steatosis and inflammation
23. Classification of hepatotoxicity of compounds based on cytotoxicity assays is improved by additional interpretable summaries of high-dimensional gene expression data
24. Risk assessment of parabens in a transcriptomics-based in vitro test
25. Ricin: an ancient toxicant, but still an evergreen
26. Sublethal necroptosis signaling promotes inflammation and liver cancer
27. Genome-wide Association Study of Bladder Cancer Reveals New Biological and Translational Insights
28. Inhibition of cytochrome P450 enhances the nephro- and hepatotoxicity of ochratoxin A
29. Colchicine overdose impairs the capacity of Kupffer cells to clear foreign particles and endotoxins
30. Hypoalbuminemia affects the spatio-temporal tissue distribution of ochratoxin A in liver and kidneys: consequences for organ toxicity
31. Stimulation of de novo glutathione synthesis by nitrofurantoin for enhanced resilience of hepatocytes
32. Chronic stress is associated with specific path integration deficits
33. Evaluation of the genotoxic potential of acrylamide: Arguments for the derivation of a tolerable daily intake (TDI value)
34. Digital twin demonstrates significance of biomechanical growth control in liver regeneration after partial hepatectomy
35. Stellungnahme zu Acetaldehyd als Aromastoff: Aspekte der Risikobewertung
36. OS-088-YI Selective ablation of Caspase 8 in hepatocytes ameliorates development of metabolic dysfunction-associated steatohepatitis following hepatocyte-specific JNK deletion
37. LBP-017 Liver-kidney crosstalk: the influence of hepatic oxalate release on kidney gluconeogenesis
38. Salivary nitrate/nitrite and acetaldehyde in humans: potential combination effects in the upper gastrointestinal tract and possible consequences for the in vivo formation of N-nitroso compounds—a hypothesis
39. Recent research on Novichok
40. Identification of an FXR-modulated liver-intestine hybrid state in iPSC-derived hepatocyte-like cells
41. In memoriam Thomas Gebel
42. Long-term prognostic significance of HER2-low and HER2-zero in node-negative breast cancer
43. In vitro/in silico prediction of drug induced steatosis in relation to oral doses and blood concentrations by the Nile Red assay
44. td2pLL: An intuitive time-dose-response model for cytotoxicity data with varying exposure durations
45. Importance of Xenobiotic Metabolism: Mechanistic Considerations Relevant for Regulation
46. Do Carcinogens Have a Threshold Dose? The Pros and Cons
47. Automated Detection of Portal Fields and Central Veins in Whole-Slide Images of Liver Tissue
48. Correction: In memoriam Thomas Gebel
49. Enigmatic mechanism of the N-vinylpyrrolidone hepatocarcinogenicity in the rat
50. Identification of Ppar γ -modulated miRNA hubs that target the fibrotic tumor microenvironment
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