Search

Your search keyword '"Goikoetxea A"' showing total 3,093 results
Start Over Author "Goikoetxea A" Publication Year Range Last 50 years
3,093 results on '"Goikoetxea A"'

1. Ranking Over Scoring: Towards Reliable and Robust Automated Evaluation of LLM-Generated Medical Explanatory Arguments

Author

De la Iglesia, Iker, Goenaga, Iakes, Ramirez-Romero, Johanna, Villa-Gonzalez, Jose Maria, Goikoetxea, Josu, and Barrena, Ander

Subjects
Computer Science - Computation and Language
Abstract

Evaluating LLM-generated text has become a key challenge, especially in domain-specific contexts like the medical field. This work introduces a novel evaluation methodology for LLM-generated medical explanatory arguments, relying on Proxy Tasks and rankings to closely align results with human evaluation criteria, overcoming the biases typically seen in LLMs used as judges. We demonstrate that the proposed evaluators are robust against adversarial attacks, including the assessment of non-argumentative text. Additionally, the human-crafted arguments needed to train the evaluators are minimized to just one example per Proxy Task. By examining multiple LLM-generated arguments, we establish a methodology for determining whether a Proxy Task is suitable for evaluating LLM-generated medical explanatory arguments, requiring only five examples and two human experts.

Published
2024

4. Clinical characteristics, predisposing factors and outcomes for Enterococcus faecalis versus Enterococcus faecium bloodstream infections: a prospective multicentre cohort study

Author

Scharloo, Fenna, Cogliati Dezza, Francesco, López-Hernández, Inmaculada, Martínez Pérez-Crespo, Pedro María, Goikoetxea Aguirre, Ane Josune, Pérez-Rodríguez, María Teresa, Fernandez-Suarez, Jonathan, León Jiménez, Eva, Morán Rodríguez, Miguel Ángel, Fernández-Natal, Isabel, Reguera Iglesias, José María, Natera Kindelán, Clara, Fariñas Álvares, Maria Carmen, Boix-Palop, Lucía, Lopez-Cortes, Luis Eduardo, and Rodríguez-Baño, Jesús

Published
2024
Full Text
View/download PDF

5. Accelerating Parkinson’s Disease drug development with federated learning approaches

Author

Khanna, Amit, Adams, Jamie, Antoniades, Chrystalina, Bloem, Bastiaan R., Carroll, Camille, Cedarbaum, Jesse, Cosman, Joshua, Dexter, David T., Dockendorf, Marissa F., Edgerton, Jeremy, Gaetano, Laura, Goikoetxea, Erkuden, Hill, Derek, Horak, Fay, Izmailova, Elena S., Kangarloo, Tairmae, Katabi, Dina, Kopil, Catherine, Lindemann, Michael, Mammen, Jennifer, Marek, Kenneth, McFarthing, Kevin, Mirelman, Anat, Muller, Martijn, Pagano, Gennaro, Peterschmitt, M. Judith, Ren, Jie, Rochester, Lynn, Sardar, Sakshi, Siderowf, Andrew, Simuni, Tanya, Stephenson, Diane, Swanson-Fischer, Christine, Wagner, John A., and Jones, Graham B.

Published
2024
Full Text
View/download PDF

6. Differences in clinical outcomes of bloodstream infections caused by Klebsiella aerogenes, Klebsiella pneumoniae and Enterobacter cloacae: a multicentre cohort study

Author

Guedes, Mariana, Gathara, David, López-Hernández, Inmaculada, Pérez-Crespo, Pedro María Martínez, Pérez-Rodríguez, María Teresa, Sousa, Adrian, Plata, Antonio, Reguera-Iglesias, Jose María, Boix-Palop, Lucía, Dietl, Beatriz, Blanco, Juan Sevilla, Castillo, Carlos Armiñanzas, Galán-Sánchez, Fátima, Kindelán, Clara Natera, Jover-Saenz, Alfredo, Aguirre, Josune Goikoetxea, Alemán, Ana Alemán, Ciordia, Teresa Marrodán, del Arco Jiménez, Alfonso, Fernandez-Suarez, Jonathan, Lopez-Cortes, Luis Eduardo, and Rodríguez-Baño, Jesús

Published
2024
Full Text
View/download PDF

7. A Contemporary Picture of Coagulase-Negative Staphylococcal Endocarditis: A Nationwide GAMES Cohort Study

Author

Fernández Sánchez, Fernando, García de Lomas, José M., Rosas, Gabriel, de la Torre Lima, Javier, Bereciartua, Elena, Blanco Vidal, María José, Blanco, Roberto, Boado, María Victoria, Lázaro, Marta Campaña, Crespo, Alejandro, Carrión, Laura Guio, Martínez de Lagos, Mikel Del Álamo, Ugarte, Gorane Euba, Goikoetxea, Ane Josune, Hierro, Marta Ibarrola, Iruretagoyena, José Ramón, Zuazabal, Josu Irurzun, López-Soria, Leire, Montejo, Miguel, Nieto, Javier, Rodrigo, David, Rodríguez, Regino, Vitoria, Yolanda, Voces, Roberto, García López, M<ce:sup loc='post">a</ce:sup> Victoria, Georgieva, Radka Ivanova, Ojeda, Guillermo, Bailón, Isabel Rodríguez, Morales, Josefa Ruiz, Rodríguez, Ignacio Álvarez, Galparsoro, Harkaitz Azkune, Boronat, Elisa Berritu, Odriozola, M<ce:sup loc='post">a</ce:sup> Jesús Bustinduy, Martín, Cristina del Bosque, Echeverría, Tomás, Yarza, Alberto Eizaguirre, Fuentes, Ana, Goenaga, Miguel Ángel, del Río, Muskilda Goyeneche, Bauza, Ángela Granda, Iribarren, José Antonio, Urkola, Xabier Kortajarena, Pérez-Moreiras López, José Ignacio, Jiménez, Ainhoa Rengel, Reviejo, Karlos, Berbejillo, Alberto Sáez, Haza, Elou Sánchez, Alda, Rosa Sebastián, Ruiz, Itziar Solla, Ugartemendia, Irati Unamuno, Anza, Diego Vicente, Villanueva Benito, Iñaki, Arrieta, Mar Zabalo, Carrasco, Rafael, Climent, Vicente, Llamas, Patricio, Merino, Esperanza, Plazas, Joaquín, Reus, Sergio, Alonso, Alicia, Bouzas, Alberto, Castelo, Brais, Cuenca, José, Gutiérrez, Laura, Ramos, Lucía, Mayo, María Rodríguez, Serrano, Joaquín Manuel, Regueiro, Dolores Sousa, Martínez Marcos, Francisco Javier, M, del Mar Alonso, Castro, Beatriz, Melian, Teresa Delgado, Sarabia, Javier Fernández, Rosado, Dácil García, González González, Julia, Lacalzada, Juan, de la Peña, Lissete Lorenzo, Ramírez, Alina Pérez, Arrondo, Pablo Prada, Moreno, Fermín Rodríguez, Ciezar, Antonio Plata, Reguera Iglesias, José M<ce:sup loc='post">a</ce:sup>, Asensi Álvarez, Víctor, Álvarez Cabo, Rubén, Caminal, Luis, de la Hera, Jesús, García, Laura, Iglesias Fraile, Lisardo, León Arguero, Víctor, Bajo, Pilar Mencia, Morales Pérez, Carlos, Rodríguez García, Raquel, Rodríguez Esteban, M<ce:sup loc='post">a</ce:sup> Ángeles, Silva, Jacobo, Almela, Manuel, Ambrosioni, Juan, Azqueta, Manuel, Brunet, Mercè, Bodro, Marta, Cartañá, Ramón, Cuervo, Guillermo, Falces, Carlos, Fernández-Pittol, Mariana J., Fita, Guillermina, Fuster, David, de la Mària, Cristina García, García-Pares, Delia, Hernández-Meneses, Marta, Pérez, Jaume Llopis, Marco, Francesc, Miró, José M., Moreno, Asunción, Nicolás, David, Ninot, Salvador, Quintana, Eduardo, Paré, Carlos, Pereda, Daniel, Pericás, Juan M., Pomar, José L., Ramírez, José, Roque, Mercè, Rovira, Irene, Sandoval, Elena, Sitges, Marta, Soy, Dolors, Téllez, Adrián, Tolosana, José M., Vidal, Bárbara, Vila, Jordi, Adán, Iván, Alonso, David, Alonso, Juan Carlos, Álvarez-Uría, Ana, Bermejo, Javier, Bouza, Emilio, Caballero, Gregorio Cuerpo, Montero, Antonia Delgado, Estévez, Agustín, Fortuny Ribas, Ramón, Gargallo, Esther, García Leoni, M<ce:sup loc='post">a</ce:sup> Eugenia, González Mansilla, Ana, González Moraga, Francisco Javier, González Ramallo, Víctor, Kestler Hernández, Martha, Hualde, Amaia Mari, Machado, Marina, Marín, Mercedes, Martínez-Sellés, Manuel, Melero, Rosa, Muñoz, Patricia, Monzón, Diego, Olmedo, María, Pedraz, Álvaro, Pinilla, Blanca, Pinto, Ángel, Rincón, Cristina, Rodríguez-Abella, Hugo, Rodríguez-Créixems, Marta, Sánchez-Pérez, Eduardo, Segado, Antonio, Toledo, Neera, Valerio, Maricela, Vázquez, Pilar, Moreno, Eduardo Verde, de la Villa, Sofía, Antorrena, Isabel, Loeches, Belén, Moreno, Mar, Ramírez, Ulises, Bastón, Verónica Rial, Romero, María, Rosillo, Sandra, Agüero Balbín, Jesús, Amado Fernández, Cristina, Armiñanzas Castillo, Carlos, Arnaiz de las Revillas, Francisco, Cobo Belaustegui, Manuel, Carmen Fariñas, María, Fariñas-Álvarez, Concepción, Fernández Sampedro, Marta, García, Iván, Garrido, Raquel, González Rico, Claudia, Gutiérrez-Fernández, Laura, Gutiérrez-Cuadra, Manuel, Gutiérrez Díez, José, Pajarón, Marcos, Parra, José Antonio, Alonso, Noelia Ruiz, Teira, Ramón, Zarauza, Jesús, Parra, Jorge Calderón, Cobo, Marta, Domínguez, Fernando, García Pavía, Pablo, Fernández Cruz, Ana, López Azor, Juan Carlos, Ramos-Martínez, Antonio, Romero, Isabel Sánchez, Centella, Tomasa, Cobo, Javier, Gioia, Francesca, Hermida, José Manuel, Moya, José Luis, Martín-Dávila, Pilar, Navas, Enrique, Oliva, Enrique, del Río, Alejandro, Rodríguez-Roda Stuart, Jorge, Ruiz, Soledad, Hidalgo Tenorio, Carmen, Sequera, Sergio, Almendro Delia, Manuel, Araji, Omar, Barquero, José Miguel, Calvo Jambrina, Román, de Cueto, Marina, Gálvez Acebal, Juan, Méndez, Irene, Morales, Isabel, López-Cortés, Luis Eduardo, de Alarcón, Arístides, Gutiérrez-Carretero, Encarnación, Lepe, José Antonio, López-Haldón, José, Luque-Márquez, Rafael, Marín, Guillermo, Ortiz-Carrellán, Antonio, Poyato Borrego, Manuel, Sánchez-Domínguez, Eladio, Alonso, Luis Javier, Azcárate, Pedro, Azcona Gutiérrez, José Manuel, Blanco, José Ramón, Armas, Estíbaliz Corral, García-Álvarez, Lara, Oteo, José Antonio, Barros Membrilla, Antonio, Ginel Iglesias, Antonino, Grillo, Sara, Petracca, Rubén Leta, López-Contreras, Joaquín, Rivera Martínez, María Alba, Álvarez, M., Fernández, A.L., Martínez, Amparo, Prieto, A., Regueiro, Benito, Tijeira, E., Vega, Marino, Aguirre Quiñonero, Amaia, Miñambres, Ángela Alonso, Gainzarain Arana, Juan Carlos, de Alaiza Ortega, Sara González, Morán Rodríguez, Miguel Ángel, Moreno Rodríguez, Anai, Ortiz de Zárate, Zuriñe, Zapirain, José Joaquín Portu, de Adana Arroniz, Ester Sáez, Sorto Sánchez, Daisy Carolina, Antonio, Sánchez-Porto, Alejandro, Úbeda Iglesias, Albert, Laura, Cánovas, Sergio, Vázquez, Elisa García, Torres, Alicia Hernández, Blázquez, Ana, de la Morena Valenzuela, Gonzalo, de Gea, José H., Martínez Toldos, M<ce:sup loc='post">a</ce:sup> Carmen, Escudero, Encarnación Moral, Oliva, M<ce:sup loc='post">a</ce:sup> José, Ortín, Alejandro, Pérez Andreu, Joaquín, Piloto, Avchel Roura, Saura, Daniel, Alonso, Ángel, Aramburu, Javier, Calvo, Felicitas Elena, Tarabini-Castellani, Paola, Heredero Gálvez, Eva, Bellido, Carolina Maicas, Largo Pau, José, Sepúlveda, M<ce:sup loc='post">a</ce:sup> Antonia, Toledano Sierra, Pilar, Zafar Iqbal-Mirza, Sadaf, Alcolea, Eva Cascales, Yañez, Ivan Keituqwa, Navarro Martínez, Julián, Peláez Ballesta, Ana, Moreno Escobar, Eduardo, Peña Monje, Alejandro, Sánchez Cabrera, Valme, Vinuesa García, David, Arrizabalaga Asenjo, María, Cifuentes Luna, Carmen, Núñez Morcillo, Juana, Pérez Seco, M<ce:sup loc='post">a</ce:sup> Cruz, Villoslada Gelabert, Aroa, Aured Guallar, Carmen, Abad, Nuria Fernández, Mangas, Pilar García, Matamala Adell, Marta, Palacián Ruiz, M<ce:sup loc='post">a</ce:sup> Pilar, Porres, Juan Carlos, Vidal, Begoña Alcaraz, Del Amor Espín, María Jesús, Buendía, Francisco, Sánchez, Roberto Jiménez, Mármol, Rosario, Martínez, Francisco, Meseguer, Antonio, Pérez, Beatriz, Risco, Leticia, Saura, Zoser, Silva, Vanina, Villmarín, M<ce:sup loc='post">a</ce:sup> Belén, Ribas Blanco, M<ce:sup loc='post">a</ce:sup> Ángels, de Gopegui Bordes, Enrique Ruiz, Vidal Bonet, Laura, Vives Borràs, Miquel, Bellón Munera, M<ce:sup loc='post">a</ce:sup> Carmen, Escribano Garaizabal, Elena, Tercero Martínez, Antonia, Segura Luque, Juan Carlos, Badía, Cristina, Boix-Palop, Lucía, Xercavins, Mariona, Ibars, Sónia, Fernández- Paniagua, Estefanía Águila, Bosch, Xerach, Gilarranz Luengo, Raúl, Gómez Nebreda, Eloy, Herrera, Ibalia Horcajada, Menduiña Gallego, Irene, Mohamed Ramírez, Karim, Pulido, Imanol, Nelson, Verónica Quevedo, Urso, Stefano, Santiago, Héctor Marrero, de Miguel Martínez, Isabel, Álamo, Elena Pisos, San Román Sánchez, Daniel, Pérez, Jorge Boan, Aguilar Blanco, Eva M., González, Mercedes Catalán, Corres Peiretti, María Angélica, Esteve, Andrea Eixerés, Pérez, Laura Domínguez, de Cossío Tejido, Santiago, Galván Román, Francisco, García Robles, José Antonio, López-Medrano, Francisco, López Gude, M<ce:sup loc='post">a</ce:sup> Jesús, Orellana Miguel, M<ce:sup loc='post">a</ce:sup> Ángeles, Pilkington, Patrick, Ostalaza, Yolanda Revilla, Morales, Juan Ruiz, Solís, Sebastián Ruiz, Collado, Ana Sabín, Sánchez Fernández, Marcos, Rallo, Javier Solera, Martín, Jorge Solís, Escrihuela-Vidal, Francesc, Carratalà, Jordi, Grau, Imma, Ardanuy, Carmen, Berbel, Dámaris, Alegre, Oriol, Mañas Jiménez, María Pilar, Notta Gonzalez, Paula Cecilia, Sbraga, Fabrizio, Blasco, Arnau, Gracia Sánchez, Laura, Sánchez-Rodríguez, Iván, Aldamiz, Gonzalo, Álvarez, Beatriz, Bernal Palacios, Marina, Cabello Úbeda, Alfonso, Fernández Roblas, Ricardo, Hernández, Rafael, Hortigüela Martín, Victoria Andrea, Kallmeyer, Andrea, Kancev, Cristina Landaeta, Martín, Marta, Ruiz, Miguel Morante, Navas Lobato, Miguel Ángel, Pello, Ana María, Prieto, Laura, Mallebrera, Marta Tomás, Varela, Laura, de la Peña Triguero, Mireia, Cerón, Ruth Esther Figueroa, Gómez, Lara Ruiz, Ble, Mireia, Horcajada Gallego, Juan Pablo, Ginel, Antonio José, López, Inmaculada, Mas, Alexandra, Mestres, Antoni, Molina, Lluís, Serrat, Ramón, Ribas, Núria, Sánchez, Francisca, Silverio, Ana, Suárez, Marina, Sorlí, Luisa, Recasens, Lluís, Taurón, Manuel, Fernández Regueras, María, Mantecón Vallejo, María Ángeles, Pérez Rivera, José Ángel, Mata, Nuria Sánchez, Calvo Cano, Antonia, Fajardo Olivares, Miguel, Millán Núñez, María Victoria, Muñoz Sanz, Agustín, Palom-Grau, Clara, Marín Arriaza, Mercedes, González-Ramallo, Víctor, Poyato-Borrego, Manuel, Rodríguez-García, Raquel, Rodríguez-Esteban, M. Ángeles, Fariñas, M. Carmen, González-Rico, Claudia, Ojeda-Burgos, Guillermo, Goikoetxea-Agirre, Ane Josune, Calderón-Parra, Jorge, López-Azor, Juan Carlos, García-Vázquez, Elisa, Quintana, Eduard, García de la Mària, Cristina, and Llopis, Jaume

Published
2025
Full Text
View/download PDF

9. Bridging Natural Language Processing and Psycholinguistics: computationally grounded semantic similarity datasets for Basque and Spanish

Author

Goikoetxea, J., Arantzeta, M., and Martin, I. San

Subjects
Computer Science - Computation and Language
Abstract

We present a computationally-grounded word similarity dataset based on two well-known Natural Language Processing resources; text corpora and knowledge bases. This dataset aims to fulfil a gap in psycholinguistic research by providing a variety of quantifications of semantic similarity in an extensive set of noun pairs controlled by variables that play a significant role in lexical processing. The dataset creation has consisted in three steps, 1) computing four key psycholinguistic features for each noun; concreteness, frequency, semantic and phonological neighbourhood density; 2) pairing nouns across these four variables; 3) for each noun pair, assigning three types of word similarity measurements, computed out of text, Wordnet and hybrid embeddings. The present dataset includes noun pairs' information in Basque and European Spanish, but further work intends to extend it to more languages.

Published
2023

10. Influence of Patient Gender on In‐Hospital Mortality: A Population‐Based Cross‐Sectional Study

Author

Nahikari Vizuete‐Aldave, Maider Ugartemendia‐Yerobi, Beatriz Pereda‐Goikoetxea, Nagore Zinkunegi‐Zubizarreta, Josune Zubeldia‐Etxeberria, Udane Elordi‐Guenaga, Haritz Arrieta, and Ainitze Labaka

Subjects
Nursing, RT1-120
Abstract

ABSTRACT Aim To analyse the association between gender and in‐hospital mortality odds ratios among patients in the Basque Country. Design Cross‐sectional study. Methods Admission data pertaining to the period between 1 January 2016 and 31 December 2018 were gathered for all registered acute care hospitals (both public and private) in the Basque Country. Odds ratios were calculated through binomial logistic regressions to determine the association between gender and mortality in each diagnostic category of the ICD‐10. Results Women had a higher in‐hospital mortality odds ratio for diseases of the circulatory system (OR 1.07 [1.01–1.14], p

Published
2025
Full Text
View/download PDF

11. Uxue Apaolazaren «Manoletinak» (Bihurguneko nasa) ipuineko ekfrasiez: irakurketa proposamen bat

Author

Leire Iruretagoiena Goikoetxea

Subjects
Uxue Apaolaza, ipuingintza, «Manoletinak», ekfrasia, genero ikasketak, Philology. Linguistics, P1-1091
Abstract

Aurrekariek diotenez, Uxue Apaolazak esangarria (ez) denaren ertzak azpimarratu ohi ditu. Ekfrasiaren gaineko azken ikerketen arabera, begiradaren gramatika eta etika da ekfrasia, eta beraz, ikus (ezin) litekeenaren isla. Hipotesi horri tiraka, Uxue Apaolazaren «Manoletinak» (Bihurguneko nasa, 2021, Euskadi Saria) ipuina aztertuko da, hain zuzen ere, bertan aipatzen den Maia Plisetskaiaren koadroa jomugatzat hartuta. Litekeena da Plisetskaiaren irudiaren ekfrasiak lirudiketenak baino esanguratsuagoak izatea eta horiek aztertuz ipuinaren muinari dagozkion irakurketak azaleratzea. Horretarako, ekfrasiaren ikerketetara ez ezik, genero ikasketetara eta harreraren teoriara ere joko da.

Published
2024
Full Text
View/download PDF

12. Energy Efficient All-Electric-Field-Controlled Multiferroic Magnetic Domain-Wall Logic

Author

Li, Xin, Singh, Hanuman, Bao, Yi, Luo, Qiang, Li, Shihao, Chatterjee, Jyotirmoy, Goiriena-Goikoetxea, Maite, Xiao, Zhuyun, Tamura, Nobumichi, Candler, Rob N, You, Long, Bokor, Jeff, and Hong, Jeongmin

Subjects
Information and Computing Sciences, Quantum Physics, Engineering, Physical Sciences, Affordable and Clean Energy, Multiferroic coupling, electric-field-controlled strain, magnetic domain wall, Boolean logic, energyefficient device, energy efficient device, Nanoscience & Nanotechnology
Abstract

Magnetic domain wall (DW)-based logic devices offer numerous opportunities for emerging electronics applications allowing superior performance characteristics such as fast motion, high density, and nonvolatility to process information. However, these devices rely on an external magnetic field, which limits their implementation; this is particularly problematic in large-scale applications. Multiferroic systems consisting of a piezoelectric substrate coupled with ferromagnets provide a potential solution that provides the possibility of controlling magnetization through an electric field via magnetoelastic coupling. Strain-induced magnetization anisotropy tilting can influence the DW motion in a controllable way. We demonstrate a method to perform all-electrical logic operations using such a system. Ferromagnetic coupling between neighboring magnetic domains induced by the electric-field-controlled strain has been exploited to promote noncollinear spin alignment, which is used for realizing essential building blocks, including DW generation, propagation, and pinning, in all implementations of Boolean logic, which will pave the way for scalable memory-in-logic applications.

Published
2023

13. Bridging Natural Language Processing and psycholinguistics: computationally grounded semantic similarity datasets for Basque and Spanish

Author

Josu Goikoetxea, Itziar San Martin, and Miren Arantzeta

Subjects
WordNet, text, psycholinguistic features, word similarity, embeddings, nouns, Language and Literature
Abstract

IntroductionSemantic relations are crucial in various cognitive processes, highlighting the need to understand concept interactions and how such relations are represented in the brain. Psycholinguistics research requires computationally grounded datasets that include word similarity measures controlled for the variables that play a significant role in lexical processing. This work presents a dataset for noun pairs in Basque and European Spanish based on two well-known Natural Language Processing resources: text corpora and knowledge bases.MethodsThe dataset creation consisted of three steps, (1) computing four key psycholinguistic features for each noun; concreteness, frequency, semantic, and phonological neighborhood density; (2) pairing nouns across these four variables; (3) for each noun pair, assigning three types of word similarity measurements, computed out of text, Wordnet and hybrid embeddings.ResultsA dataset of noun pairs in Basque and Spanish involving three types of word similarity measurements, along with four lexical features for each of the nouns in the pair, namely, word frequency, concreteness, and semantic and phonological neighbors. The selection of the nouns for each pair was controlled by the mentioned variables, which play a significant role in lexical processing. The dataset includes three similarity measurements, based on their embedding computation: semantic relatedness from text-based embeddings, pure similarity from Wordnet-based embeddings and both categorical and associative relations from hybrid embeddings.DiscussionThe present work covers an existent gap in Basque and Spanish in terms of the lack of datasets that include both word similarity and detailed lexical properties, which provides a more useful resource for psycholinguistics research in those languages.

Published
2024
Full Text
View/download PDF

14. Responses of several measures to different intensity levels of upper limb exergames in children with neurological diagnoses: a pilot study

Author

Gaizka Goikoetxea-Sotelo and Hubertus J. A. van Hedel

Subjects
intensity measures, neurorehabilitation, movement repetitions, heart rate variability, activity counts, skin conductance, Other systems of medicine, RZ201-999, Medical technology, R855-855.5
Abstract

BackgroundTherapy intensity is among the most critical factors influencing neurorehabilitative outcomes. Because of its simplicity, time spent in therapy is the most commonly used measure of therapy intensity. However, time spent in therapy is only a vague estimate of how hard a patient works during therapy. Several measures have been proposed to better capture the amount of work a patient puts forth during therapy. Still, it has never been analyzed how these measures respond to changes in therapist-selected exercise intensity in children with neurological conditions.ObjectivesTo investigate the response and the reliability of heart rate variability (HRV), skin conductance (SC), activity counts per minute (AC/min), movement repetitions per minute (MOV/min), and perceived exertion to different therapist-tailored intensity levels of upper limb technology-assisted therapy in children with neurological conditions.MethodsIn this pilot cross-sectional study, participants engaged in three personalized, randomized exergame intensity levels (“very easy”, “challenging”, “very difficult”) for eight minutes each. We assessed all measures at each intensity level. The experiment was conducted twice on two consecutive days. We quantified reliability using intra-class correlation coefficients (ICC).ResultsWe included 12 children and adolescents aged 11.92 (±3.03) years. HRV, MOV/min, and perceived exertion could differentiate among the three intensity levels. HRV, MOV/min, perceived exertion, and AC/min showed moderate to excellent (0.62 ≤ ICC ≤ 0.98) test-retest reliability.ConclusionHRV, MOV/min, and perceived exertion show potential for becoming valid and reliable intensity measures for an upper limb robotic rehabilitative setting. However, studies with larger sample sizes and more standardized approaches are needed to understand these measures’ responses better.

Published
2024
Full Text
View/download PDF

15. Isavuconazole Versus Voriconazole as the First-line Therapy for Solid Organ Transplant Recipients With Invasive Aspergillosis: Comparative Analysis of 2 Multicenter Cohort Studies

Author

Fernández-Ruiz, Mario, Gioia, Francesca, Bodro, Marta, Gutiérrez Martín, Isabel, Sabé, Núria, Rodriguez-Álvarez, Regino, Corbella, Laura, López-Viñau, Teresa, Valerio, Maricela, Illaro, Aitziber, Salto-Alejandre, Sonsoles, Cordero, Elisa, Arnaiz de Las Revillas, Francisco, Fariñas, María Carmen, Muñoz, Patricia, Vidal, Elisa, Carratalà, Jordi, Goikoetxea, Josune, Ramos-Martínez, Antonio, Moreno, Asunción, Martín-Dávila, Pilar, Fortún, Jesús, and Aguado, José María

Published
2024
Full Text
View/download PDF

16. Multiplet Effects in the Electronic Correlation of One-Dimensional Magnetic Transition-Metal Oxides on Metals

Author

Goikoetxea, J., Friedrich, C., Bihlmayer, G., Blügel, S., Arnau, A., and Blanco-Rey, M.

Subjects
Condensed Matter - Materials Science, Condensed Matter - Strongly Correlated Electrons
Abstract

We use the constrained random phase approximation (cRPA) method to calculate the Hubbard $U$ parameter in four one-dimensional magnetic transition metal atom oxides of composition XO$_2$ (X = Mn, Fe, Co, Ni) on Ir(100). In addition to the expected screening of the oxide, i.e., a significant reduction of the $U$ value by the presence of the metal substrate, we find a strong dependence on the electronic configuration (multiplet) of the X($d$) orbital. Each particular electronic configuration attained by atom X is dictated by the O ligands, as well as by the charge transfer and hybridization with the Ir(100) substrate. We find that MnO$_2$ and NiO$_2$ chains exhibit two different screening regimes, while the case of CoO$_2$ is somewhere in between. The electronic structure of the MnO$_2$ chain remains almost unchanged upon adsorption. Therefore, in this regime, the additional screening is predominantly generated by the electrons of the neighboring metal surface atoms. The screening strength for NiO$_2$/Ir(100) is found to depend on the Ni($d$) configuration in the adsorbed state. The case of FeO$_2$ shows an exceptional behavior, as it is the only insulating system in the absence of metallic substrate and, thus, it has the largest $U$ value. However, this value is significantly reduced by the two mentioned screening effects after adsorption., Comment: Main paper: 9 pages, 4 figures, 3 tables. Supplemental Material: 15 pages, 8 figures, 6 tables

Published
2022
Full Text
View/download PDF

17. The Role of the Magnetic Anisotropy in Atomic-Spin Sensing of 1D Molecular Chains

Author

Wäckerlin, Christian, Cahlík, Aleš, Goikoetxea, Joseba, Stesovych, Oleksandr, Medvedeva, Daria, Redondo, Jesús, Švec, Martin, Delley, Bernard, Ondráček, Martin, Pinar, Andres, Blanco-Rey, Maria, Kolorenc, Jindrich, Arnau, Andres, and Jelínek, Pavel

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics, Condensed Matter - Strongly Correlated Electrons
Abstract

One-dimensional metal-organic chains often possess a complex magnetic structure susceptible to be modified by a alteration of their chemical composition. The possibility to tune their magnetic properties provides an interesting playground to explore quasiparticle interactions in low-dimensional systems. Despite the great effort invested so far, a detailed understanding of the interactions governing the electronic and magnetic properties of the low-dimensional systems is still incomplete. One of the reasons is the limited ability to characterize their magnetic properties at the atomic scale. Here, we provide a comprehensive study of the magnetic properties of metal-organic one-dimensional (1D) coordination polymers consisting of 2,5-diamino-1,4-benzoquinonediimine ligands coordinated with Co or Cr atoms synthesized in ultra-high vacuum conditions on a Au(111) surface. A combination of an integral X-ray spectroscopy with local-probe inelastic electron tunneling spectroscopy corroborated by multiplet analysis, density functional theory, and inelastic electron tunneling simulations enable us to obtain essential information about their magnetic structure, including the spin magnitude and orientation at the magnetic atoms, as well as the magnetic anisotropy., Comment: 35 pages, 8 Figures, 3 tables

Published
2022
Full Text
View/download PDF

18. Early antibiotic de-escalation in patients with severe infections due to bloodstream infection by enterobacterales: A post hoc analysis of a prospective multicentre cohort

Author

Retamar-Gentil, Pilar, Ferrer, José Bravo, García, Marcos Guzmán, García, David Vinuesa, Gea-Lázaro, Isabel, Natal, Isabel Fernández, Porto, Antonio Sánchez, Pérez-Camacho, Inés, León, Eva, de Lucas, Esperanza Merino, Fariñas, Maria Carmen, Reche, Isabel, Escrihuela-Vidal, Francesc, Palacios-Baena, Zaira R., Agirre, Josune Goikoetxea, Pérez-Rodríguez, María Teresa, Reguera Iglesias, José María, Cuquet Pedragosa, Jordi, Sánchez Gómez, Leticia, Boix-Palop, Lucía, Bahamonde Carrasco, Alberto, Natera-Kindelán, Clara, Fernández-Suárez, Jonathan, Jover-Sáenz, Alfredo, Smithson Amat, Alejandro, del Arco Jiménez, Alfonso, Sánchez Calvo, Juan Manuel, Martín-Aspas, Andrés, Martínez Pérez-Crespo, Pedro María, López-Hernández, Inmaculada, Rodríguez-Baño, Jesús, and López-Cortés, Luis Eduardo

Published
2024
Full Text
View/download PDF

20. The lipopolysaccharide-TLR4 axis regulates hepatic glutaminase 1 expression promoting liver ammonia build-up as steatotic liver disease progresses to steatohepatitis

Author

Mercado-Gómez, Maria, Goikoetxea-Usandizaga, Naroa, Kerbert, Annarein J.C., Gracianteparaluceta, Leire Uraga, Serrano-Maciá, Marina, Lachiondo-Ortega, Sofia, Rodriguez-Agudo, Rubén, Gil-Pitarch, Clàudia, Simón, Jorge, González-Recio, Irene, Fondevila, Marcos F., Santamarina-Ojeda, Pablo, Fraga, Mario F., Nogueiras, Rubén, Heras, Javier de las, Jalan, Rajiv, Martínez-Chantar, María Luz, and Delgado, Teresa C.

Published
2024
Full Text
View/download PDF

24. Mortality impact of further delays in active targeted antibiotic therapy in bacteraemic patients that did not receive initial active empiric treatment: Results from the prospective, multicentre cohort PROBAC

Author

Sandra De la Rosa-Riestra, Pedro María Martínez Pérez-Crespo, María Teresa Pérez Rodríguez, Adrián Sousa, Josune Goikoetxea, José María Reguera Iglesias, Carlos Armiñanzas, Inmaculada López-Hernández, Luis E. López-Cortés, and Jesús Rodríguez-Baño

Subjects
Bacteraemia, Delayed therapy, Targeted therapy, Mortality, Cohort study multicentre study, Infectious and parasitic diseases, RC109-216
Abstract

Objectives: The early initiation of the empirical antibiotic treatment and its impact on mortality in patients with bacteraemia has been extensively studied. However, information on the impact of precocity of the targeted antibiotic treatment is scarce. We aimed to study the impact of further delay in active antibiotic therapy on 30-day mortality among patients with bloodstream infection who had not received appropriate empirical therapy. Design: We worked with PROBAC cohort (prospective and compound by patients from 26 different Spanish hospitals). We selected a total of 1703 patients, who survived to day 2 without having received any active antibiotic therapy against the causative pathogen. Results: The 30-day mortality was 14% (238 patients). The adjusted odds of mortality increased for every day of delay, from 1.53 (95% confidence interval (CI) 1.13-2.08) for day 3 or after to 11.38 (95% CI 7.95-16.38) for day 6 or after. Conclusion: We concluded that among patients who had not received active treatment within the first 2 days of blood culture collection, additional delays in active targeted therapy were associated with increased mortality. These results emphasize the importance of active interventions in the management of patients with bloodstream infections.

Published
2024
Full Text
View/download PDF

25. Bacille Calmette-Guérin vaccination to prevent febrile and respiratory illness in adults (BRACE): secondary outcomes of a randomised controlled phase 3 trialResearch in context

Author

Laure F. Pittet, Nicole L. Messina, Ellie McDonald, Francesca Orsini, Simone Barry, Marc Bonten, John Campbell, Julio Croda, Mariana G. Croda, Margareth Dalcolmo, Kaya Gardiner, Amanda Gwee, Bruno Jardim, Marcus V.G. Lacerda, Michaela Lucas, David J. Lynn, Laurens Manning, Kirsten P. Perrett, Jeffrey J. Post, Cristina Prat-Aymerich, Peter C. Richmond, Jorge L. Rocha, Jesus Rodriguez-Baño, Adilia Warris, Nicholas J. Wood, Andrew Davidson, Nigel Curtis, Tenaya Jamieson, Nicole Messina, Thilanka Morawakage, Susan Perlen, Kirsten Perrett, Laure Pittet, Amber Sastry, Jia Wei Teo, Katherine Lee, Cecilia Moore, Suzanna Vidmar, Rashida Ali, Ross Dunn, Peta Edler, Grace Gell, Casey Goodall, Richard Hall, Ann Krastev, Nathan La, Nick McPhate, Thao Nguyen, Jack Ren, Luke Stevens, Ahmed Alamrousi, Rhian Bonnici, Thanh Dang, Susie Germano, Jenny Hua, Rebecca McElroy, Monica Razmovska, Scott Reddiex, Xiaofang Wang, Jeremy Anderson, Kristy Azzopardi, Vicki Bennett-Wood, Anna Czajko, Nadia Mazarakis, Conor McCafferty, Frances Oppedisano, Belinda Ortika, Casey Pell, Leena Spry, Ryan Toh, Sunitha Velagapudi, Amanda Vlahos, Ashleigh Wee-Hee, Pedro Ramos, Karina De La Cruz, Dinusha Gamage, Anushka Karunanayake, Isabella Mezzetti, Benjamin Ong, Ronita Singh, Enoshini Sooriyarachchi, Suellen Nicholson, Natalie Cain, Rianne Brizuela, Han Huang, Veronica Abruzzo, Morgan Bealing, Patricia Bimboese, Kirsty Bowes, Emma Burrell, Joyce Chan, Jac Cushnahan, Hannah Elborough, Olivia Elkington, Kieran Fahey, Monique Fernandez, Catherine Flynn, Sarah Fowler, Marie Gentile Andrit, Bojana Gladanac, Catherine Hammond, Norine Ma, Sam Macalister, Emmah Milojevic, Jesutofunmi Mojeed, Jill Nguyen, Liz O'Donnell, Nadia Olivier, Isabelle Ooi, Stephanie Reynolds, Lisa Shen, Barb Sherry, Judith Spotswood, Jamie Wedderburn, Angela Younes, Donna Legge, Jason Bell, Jo Cheah, Annie Cobbledick, Kee Lim, Sonja Elia, Lynne Addlem, Anna Bourke, Clare Brophy, Nadine Henare, Narelle Jenkins, Francesca Machingaifa, Skye Miller, Kirsten Mitchell, Sigrid Pitkin, Kate Wall, Paola Villanueva, Nigel Crawford, Wendy Norton, Niki Tan, Thilakavathi Chengodu, Diane Dawson, Victoria Gordon, Tony Korman, Jess O'Bryan, Sophie Agius, Samantha Bannister, Jess Bucholc, Alison Burns, Beatriz Camesella, John Carlin, Marianna Ciaverella, Maxwell Curtis, Stephanie Firth, Christina Guo, Matthew Hannan, Erin Hill, Sri Joshi, Katherine Lieschke, Megan Mathers, Sasha Odoi, Ashleigh Rak, Chris Richards, Leah Steve, Carolyn Stewart, Eva Sudbury, Helen Thomson, Emma Watts, Fiona Williams, Angela Young, Penny Glenn, Andrew Kaynes, Amandine Philippart De Floy, Sandy Buchanan, Thijs Sondag, Ivy Xie, Harriet Edmund, Bridie Byrne, Tom Keeble, Belle Ngien, Fran Noonan, Michelle Wearing-Smith, Alison Clarke, Pemma Davies, Oliver Eastwood, Alric Ellinghaus, Rachid Ghieh, Zahra Hilton, Emma Jennings, Athina Kakkos, Iris Liang, Katie Nicol, Sally O'Callaghan, Helen Osman, Gowri Rajaram, Sophia Ratcliffe, Victoria Rayner, Ashleigh Salmon, Angela Scheppokat, Aimee Stevens, Rebekah Street, Nicholas Toogood, Nicholas Wood, Twinkle Bahaduri, Therese Baulman, Jennifer Byrne, Candace Carter, Mary Corbett, Aiken Dao, Maria Desylva, Andrew Dunn, Evangeline Gardiner, Rosemary Joyce, Rama Kandasamy, Craig Munns, Lisa Pelayo, Ketaki Sharma, Katrina Sterling, Caitlin Uren, Clinton Colaco, Mark Douglas, Kate Hamilton, Adam Bartlett, Brendan McMullan, Pamela Palasanthiran, Phoebe Williams, Justin Beardsley, Nikki Bergant, Renier Lagunday, Kristen Overton, Jeffrey Post, Yasmeen Al-Hindawi, Sarah Barney, Anthony Byrne, Lee Mead, Marshall Plit, David Lynn, Saoirse Benson, Stephen Blake, Rochelle Botten, Tee Yee Chern, Georgina Eden, Liddy Griffith, Jane James, Miriam Lynn, Angela Markow, Domenic Sacca, Natalie Stevens, Steve Wesselingh, Catriona Doran, Alice Sawka, Sue Evans, Louise Goodchild, Christine Heath, Meredith Krieg, Helen Marshall, Mark McMillan, Mary Walker, Peter Richmond, Nelly Amenyogbe, Christina Anthony, Annabelle Arnold, Beth Arrowsmith, Rym Ben-Othman, Sharon Clark, Jemma Dunnill, Nat Eiffler, Krist Ewe, Carolyn Finucane, Lorraine Flynn, Camille Gibson, Lucy Hartnell, Elysia Hollams, Heidi Hutton, Lance Jarvis, Jane Jones, Jan Jones, Karen Jones, Jennifer Kent, Tobias Kollmann, Debbie Lalich, Wenna Lee, Rachel Lim, Sonia McAlister, Fiona McDonald, Andrea Meehan, Asma Minhaj, Lisa Montgomery, Melissa O'Donnell, Jaslyn Ong, Joanne Ong, Kimberley Parkin, Glady Perez, Catherine Power, Shadie Rezazadeh, Holly Richmond, Sally Rogers, Nikki Schultz, Margaret Shave, Patrycja Skut, Lisa Stiglmayer, Alexandra Truelove, Ushma Wadia, Rachael Wallace, Justin Waring, Michelle England, Erin Latkovic, Susan Herrmann, Marcus Lacerda, Paulo Henrique Andrade, Fabiane Bianca Barbosa, Dayanne Barros, Larissa Brasil, Ana Greyce Capella, Ramon Castro, Erlane Costa, Dilcimar de Souza, Maianne Dias, José Dias, Klenilson Ferreira, Paula Figueiredo, Thamires Freitas, Ana Carolina Furtado, Larissa Gama, Vanessa Godinho, Cintia Gouy, Daniele Hinojosa, Tyane Jardim, Joel Junior, Augustto Lima, Bernardo Maia, Adriana Marins, Kelry Mazurega, Tercilene Medeiros, Rosangela Melo, Marinete Moraes, Elizandra Nascimento, Juliana Neves, Maria Gabriela Oliveira, Thais Oliveira, Ingrid Oliveira, Arthur Otsuka, Rayssa Paes, Handerson Pereira, Gabrielle Pereira, Christiane Prado, Evelyn Queiroz, Laleyska Rodrigues, Bebeto Rodrigues, Vanderson Sampaio, Anna Gabriela Santos, Daniel Santos, Tilza Santos, Evelyn Santos, Ariandra Sartim, Ana Beatriz Silva, Juliana Silva, Emanuelle Silva, Mariana Simão, Caroline Soares, Antonny Sousa, Alexandre Trindade, Fernando Val, Adria Vasconcelos, Heline Vasconcelos, Carolinne Abreu, Katya Martinez Almeida, Camila Bitencourt de Andrade, Jhenyfer Thalyta Campos Angelo, Ghislaine Gonçalvez de Araújo Arcanjo, Bianca Maria Silva Menezes Arruda, Wellyngthon Espindola Ayala, Adelita Agripina Refosco Barbosa, Felipe Zampieri Vieira Batista, Fabiani de Morais Batista, Miriam de Jesus Costa, Mariana Garcia Croda, Lais Alves da Cruz, Roberta Carolina Pereira Diogo, Rodrigo Cezar Dutra Escobar, Iara Rodrigues Fernandes, Leticia Ramires Figueiredo, Leandro Galdino Cavalcanti Gonçalves, Sarita Lahdo, Joyce dos Santos Lencina, Guilherme Teodoro de Lima, Bruna Tayara LEOPOLDINA MEIRELES, Debora Quadros Moreira, Lilian Batista Silva Muranaka, Adriely de Oliveira, Karla Regina Warszawski de Oliveira, Matheus Vieira de Oliveira, Roberto Dias de Oliveira, Andrea Antonia Souza de Almeida dos Reis Pereira, Marco Puga, Caroliny Veron Ramos, Thaynara Haynara Souza da Rosa, Karla Lopes dos Santos, Claudinalva Ribeiro dos Santos, Dyenyffer Stéffany Leopoldina dos Santos, Karina Marques Santos, Paulo César Pereira da Silva, Paulo Victor Rocha da Silva, Débora dos Santos Silva, Patricia Vieira da Silva, Bruno Freitas da Rosa Soares, Mariana Gazzoni Sperotto, Mariana Mayumi Tadokoro, Daniel Tsuha, Hugo Miguel Ramos Vieira, Margareth Maria Pretti Dalcolmo, Cíntia Maria Lopes Alves da Paixão, Gabriela Corrêa E Castro, Simone Silva Collopy, Renato da Costa Silva, Samyra Almeida da Silveira, Alda Maria Da-Cruz, Alessandra Maria da Silva Passos de Carvalho, Rita de Cássia Batista, Maria Luciana Silva De Freitas, Aline Gerhardt de Oliveira Ferreira, Ana Paula Conceição de Souza, Paola Cerbino Doblas, Ayla Alcoforado da Silva dos Santos, Vanessa Cristine de Moraes dos Santos, Dayane Alves dos Santos Gomes, Anderson Lage Fortunato, Adriano Gomes-Silva, Monique Pinto Gonçalves, Paulo Leandro Garcia Meireless Junior, Estela Martins da Costa Carvalho, Fernando do Couto Motta, Ligia Maria Olivo de Mendonça, Girlene dos Santos Pandine, Rosa Maria Plácido Pereira, Ivan Ramos Maia, Jorge Luiz da Rocha, João Victor Paiva Romano, Glauce dos Santos, Erica Fernandes da Silva, Marilda Agudo Mendonça Teixeira de Siqueira, Ágatha Cristinne Prudêncio Soares, Sandra Franch Arroyo, Henny Ophorst-den Besten, Anna Boon, Karin M. Brakke, Axel Janssen, Marijke A.H. Koopmans, Toos Lemmens, Titia Leurink, Engelien Septer-Bijleveld, Kimberly Stadhouders, Darren Troeman, Marije van der Waal, Marjoleine van Opdorp, Nicolette van Sluis, Beatrijs Wolters, Jan Kluytmans, Jannie Romme, Wouter van den Bijllaardt, Linda van Mook, M.M.L (Miranda) van Rijen, P.M.G. Filius, Jet Gisolf, Frances Greven, Danique Huijbens, Robert Jan Hassing, R.C. Pon, Lieke Preijers, J.H. van Leusen, Harald Verheij, Wim Boersma, Evelien Brans, Paul Kloeg, Kitty Molenaar-Groot, Nhat Khanh Nguyen, Nienke Paternotte, Anke Rol, Lida Stooper, Helga Dijkstra, Esther Eggenhuizen, Lucas Huijs, Simone Moorlag, Mihai Netea, Eva Pranger, Esther Taks, Jaap ten Oever, Rob ter Heine, Kitty Blauwendraat, Bob Meek, Isil Erkaya, Houda Harbech, Nienke Roescher, Rifka Peeters, Menno te Riele, Carmen Zhou, Esther Calbo, Cristina Badia Marti, Emma Triviño Palomares, Tomás Perez Porcuna, Anabel Barriocanal, Ana Maria Barriocanal, Irma Casas, Jose Dominguez, Maria Esteve, Alicia Lacoma, Irene Latorre, Gemma Molina, Barbara Molina, Antoni Rosell, Sandra Vidal, Lydia Barrera, Natalia Bustos, Ines Portillo Calderón, David Gutierrez Campos, Jose Manuel Carretero, Angel Dominguez Castellano, Renato Compagnone, Encarnacion Ramirez de Arellano, Almudena de la Serna, Maria Dolores del Toro Lopez, Marie-Alix Clement Espindola, Ana Belen Martin Gutierrez, Alvaro Pascual Hernandez, Virginia Palomo Jiménez, Elisa Moreno, Nicolas Navarrete, Teresa Rodriguez Paño, Jesús Rodríguez-Baño, Enriqueta Tristán, Maria Jose Rios Villegas, Atsegiñe Canga Garces, Erika Castro Amo, Raquel Coya Guerrero, Josune Goikoetxea, Leticia Jorge, Cristina Perez, María Carmen Fariñas Álvarez, Manuel Gutierrez Cuadra, Francisco Arnaiz de las Revillas Almajano, Pilar Bohedo Garcia, Teresa Giménez Poderos, Claudia González Rico, Blanca Sanchez, Olga Valero, Noelia Vega, Anna Barnes, Helen Catterick, Tim Cranston, Phoebe Dawe, Emily Fletcher, Liam Fouracre, Alison Gifford, Neil Gow, John Kirkwood, Christopher Martin, Amy McAnew, Marcus Mitchell, Georgina Newman, Abby O'Connell, Jakob Onysk, Lynne Quinn, Shelley Rhodes, Samuel Stone, Lorrie Symons, Harry Tripp, Darcy Watkins, Bethany Whale, Alex Harding, Gemma Lockhart, Kate Sidaway-Lee, Sam Hilton, Sarah Manton, Daniel Webber-Rookes, Rachel Winder, James Moore, Freya Bateman, Michael Gibbons, Bridget Knight, Julie Moss, Sarah Statton, Josephine Studham, Lydia Hall, Will Moyle, and Tamsin Venton

Subjects
Bacille Calmette-Guérin (BCG) vaccine, Immunity, Heterologous, Health personnel, Randomised controlled trial, Primary prevention, Medicine (General), R5-920
Abstract

Summary: Background: Bacille Calmette-Guérin (BCG) vaccination has off-target (non-specific) effects that are associated with protection against unrelated infections and decreased all-cause mortality in infants. We aimed to determine whether BCG vaccination prevents febrile and respiratory infections in adults. Methods: This randomised controlled phase 3 trial was done in 36 healthcare centres in Australia, Brazil, the Netherlands, Spain, and the United Kingdom. Healthcare workers were randomised to receive BCG-Denmark (single 0.1 ml intradermal injection) or no BCG in a 1:1 ratio using a web-based procedure, stratified by stage, site, age, and presence of co-morbidity. The difference in occurrence of febrile or respiratory illness were measured over 12 months (prespecified secondary outcome) using the intention-to-treat (ITT) population. This trial is registered with ClinicalTrials.gov, NCT04327206. Findings: Between March 30, 2020, and April 1, 2021, 6828 healthcare workers were randomised to BCG-Denmark (n = 3417) or control (n = 3411; no intervention or placebo) groups. The 12-month adjusted estimated risk of ≥1 episode of febrile or respiratory illness was 66.8% in the BCG group (95% CI 65.3%–68.2%), compared with 63.4% in the control group (95% CI 61.8%–65.0%), a difference of +3.4 percentage points (95% CI +1.3% to +5.5%; p 0.002). The adjusted estimated risk of a severe episode (defined as being incapacitated for ≥3 consecutive days or hospitalised) was 19.4% in the BCG group (95% CI 18.0%–20.7%), compared with 18.8% in the control group (95% CI 17.4%–20.2%) a difference of +0.6 percentage points (95% CI −1.3% to +2.5%; p 0.6). Both groups had a similar number of episodes of illness, pneumonia, and hospitalisation. There were three deaths, all in the control group. There were no safety concerns following BCG vaccination. Interpretation: In contrast to the beneficial off-target effects reported following neonatal BCG in infants, a small increased risk of symptomatic febrile or respiratory illness was observed in the 12 months following BCG vaccination in adults. There was no evidence of a difference in the risk of severe disease. Funding: Bill & Melinda Gates Foundation, Minderoo Foundation, Sarah and Lachlan Murdoch, the Royal Children's Hospital Foundation, Health Services Union NSW, the Peter Sowerby Foundation, SA Health, the Insurance Advisernet Foundation, the NAB Foundation, the Calvert-Jones Foundation, the Modara Pines Charitable Foundation, the UHG Foundation Pty Ltd, Epworth Healthcare, the National Health and Medical Research Council, the Swiss National Science Foundation and individual donors.

Published
2024
Full Text
View/download PDF

26. Gernikaren ekfrasiak Harkaitz Canoren Belarraren ahoan

Author

Leire Iruretagoiena Goikoetxea

Subjects
Gernika(k), ekfrasia, Belarraren ahoa, intermedialitatea, memoria-ikasketak, Philology. Linguistics, P1-1091
Abstract

Gernikaren ekfrasiak aztertuko dira Canoren Belarraren ahoan, memoria-ikasketak, intermedialitatea eta narratologia oinarri. Euskal literaturaren arlotik Gernikaren islak ikertzean bonbardaketaren errepresentazio historikoek erakarri dute arretarik handiena. Gernikaren irudikapenen analisira koadroaren ekfrasiak gehituz, eraldatzen/anizten ote dira testuen irakurketak? Gernika testuratzen duen euskal literatura garaikideak, aurrekariek diotenez, euskal politikaren erradikalizazioa berrikustea du helburu. Ekfrasiak arakatuz gogoeta gehiago sustatzeko joera ere antzeman da: memorien talka, arte-adierazpenen muga lausoa, artearen funtzio politikoa eta traumari bide emateko gaitasuna...

Published
2024
Full Text
View/download PDF

27. Contemporary use of cefazolin for MSSA infective endocarditis: analysis of a national prospective cohort

Author

Laura Herrera-Hidalgo, Patricia Muñoz, Ana Álvarez-Uría, David Alonso-Menchén, Rafael Luque-Marquez, Encarnación Gutiérrez-Carretero, María Del Carmen Fariñas, Jose Maria Miró, Miguel Angel Goenaga, Luis Eduardo López-Cortés, Basilio Angulo-Lara, Lucia Boix-Palop, Arístides de Alarcón, Fernando Fernández Sánchez, José Mª García de Lomas, Gabriel Rosas, Javier de la Torre Lima, Elena Bereciartua, María José Blanco Vidal, Roberto Blanco, María Victoria Boado, Marta Campaña Lázaro, Alejandro Crespo, Laura Guio Carrión, Mikel Del Álamo Martínez de Lagos, Gorane Euba Ugarte, Ane Josune Goikoetxea, Marta Ibarrola Hierro, José Ramón Iruretagoyena, Josu Irurzun Zuazabal, Leire López-Soria, Miguel Montejo, Javier Nieto, David Rodrigo, Regino Rodríguez, Yolanda Vitoria, Roberto Voces, Mª Victoria García López, Radka Ivanova Georgieva, Guillermo Ojeda, Isabel Rodríguez Bailón, Josefa Ruiz Morales, Ignacio Álvarez Rodríguez, Harkaitz Azkune Galparsoro, Elisa Berritu Boronat, Mª Jesús Bustinduy Odriozola, Cristina del Bosque Martín, Tomás Echeverría, Alberto Eizaguirre Yarza, Ana Fuentes, Miguel Ángel Goenaga, Muskilda Goyeneche del Río, Ángela Granda Bauza, José Antonio Iribarren, Xabier Kortajarena Urkola, José Ignacio Pérez-Moreiras López, Ainhoa Rengel Jiménez, Karlos Reviejo, Alberto Sáez Berbejillo, Elou Sánchez Haza, Rosa Sebastián Alda, Itziar Solla Ruiz, Irati Unamuno Ugartemendia, Diego Vicente Anza, Iñaki Villanueva Benito, Mar Zabalo Arrieta, Rafael Carrasco, Vicente Climent, Patricio Llamas, Esperanza Merino, Joaquín Plazas, Sergio Reus, Alberto Bouzas, Brais Castelo, José Cuenca, Laura Gutiérrez, Lucía Ramos, María Rodríguez Mayo, Joaquín Manuel Serrano, Dolores Sousa Regueiro, Francisco Javier Martínez, Mª del Mar Alonso, Beatriz Castro, Teresa Delgado Melian, Javier Fernández Sarabia, Dácil García Rosado, Julia González González, Juan Lacalzada, Lissete Lorenzo de la Peña, Alina Pérez Ramírez, Pablo Prada Arrondo, Fermín Rodríguez Moreno, Antonio Plata Ciezar, José Mª Reguera Iglesias, Víctor Asensi Álvarez, Carlos Costas, Jesús de la Hera, Jonnathan Fernández Suárez, Lisardo Iglesias Fraile, Víctor León Arguero, José López Menéndez, Pilar Mencia Bajo, Carlos Morales, Alfonso Moreno Torrico, Carmen Palomo, Begoña Paya Martínez, Ángeles Rodríguez Esteban, Raquel Rodríguez García, Mauricio Telenti Asensio, Manuel Almela, Juan Ambrosioni, Manuel Azqueta, Mercè Brunet, Marta Bodro, Ramón Cartañá, Guillermo Cuervo, Carlos Falces, Mariana J Fernández-Pittol, Guillermina Fita, David Fuster, Cristina García de la Mària, Delia García-Pares, Marta Hernández-Meneses, Jaume Llopis Pérez, Francesc Marco, José M. Miró, Asunción Moreno, David Nicolás, Salvador Ninot, Eduardo Quintana, Carlos Paré, Daniel Pereda, Juan M. Pericás, José L. Pomar, José Ramírez, Mercè Roque, Irene Rovira, Elena Sandoval, Marta Sitges, Dolors Soy, Adrián Téllez, José M. Tolosana, Bárbara Vidal, Jordi Vila, Iván Adán, David Alonso, Juan Carlos Alonso, Javier Bermejo, Emilio Bouza, Gregorio Cuerpo Caballero, Antonia Delgado Montero, Agustín Estévez, Ramón Fortuny Ribas, Esther Gargallo, Mª Eugenia García Leoni, Ana González Mansilla, Francisco Javier González Moraga, Víctor González Ramallo, Martha Kestler Hernández, Amaia Mari Hualde, Marina Machado, Mercedes Marín, Manuel Martínez-Sellés, Rosa Melero, Diego Monzón, María Olmedo, Álvaro Pedraz, Blanca Pinilla, Ángel Pinto, Cristina Rincón, Hugo Rodríguez-Abella, Marta Rodríguez-Créixems, Eduardo Sánchez-Pérez, Antonio Segado, Neera Toledo, Maricela Valerio, Pilar Vázquez, Eduardo Verde Moreno, Sofía de la Villa, Isabel Antorrena, Belén Loeches, Mar Moreno, Ulises Ramírez, Verónica Rial Bastón, María Romero, Sandra Rosillo, Jesús Agüero Balbín, Cristina Amado Fernández, Carlos Armiñanzas Castillo, Francisco Arnaiz de las Revillas, Manuel Cobo Belaustegui, María Carmen Fariñas, Concepción Fariñas-Álvarez, Marta Fernández Sampedro, Iván García, Claudia González Rico, Laura Gutiérrez-Fernández, Manuel Gutiérrez-Cuadra, José Gutiérrez Díez, Marcos Pajarón, José Antonio Parra, Ramón Teira, Jesús Zarauza, Jorge Calderón Parra, Marta Cobo, Fernando Domínguez, Pablo García Pavía, Ana Fernández Cruz, Antonio Ramos-Martínez, Isabel Sánchez Romero, Tomasa Centella, José Manuel Hermida, José Luis Moya, Pilar Martín-Dávila, Enrique Navas, Enrique Oliva, Alejandro del Río, Jorge Rodríguez-Roda Stuart, Soledad Ruiz, Carmen Hidalgo Tenorio, Sergio Sequera, Manuel Almendro Delia, Omar Araji, José Miguel Barquero, Román Calvo Jambrina, Marina de Cueto, Juan Gálvez Acebal, Irene Méndez, Isabel Morales, José Antonio Lepe, José López-Haldón, Rafael Luque-Márquez, Guillermo Marín, Antonio Ortiz-Carrellán, Eladio Sánchez-Domínguez, Luis Javier Alonso, Pedro Azcárate, José Manuel Azcona Gutiérrez, José Ramón Blanco, Estíbaliz Corral Armas, Lara García-Álvarez, José Antonio Oteo, Antonio Barros Membrilla, Antonino Ginel Iglesias, Sara Grillo, Rubén Leta Petracca, Joaquín López-Contreras, María Alba Rivera Martínez, M. Álvarez, A.L. Fernández, Amparo Martínez, A. Prieto, Benito Regueiro, E. Tijeira, Marino Vega, Amaia Aguirre Quiñonero, Ángela Alonso Miñambres, Juan Carlos Gainzarain Arana, Sara González de Alaiza Ortega, Miguel Ángel Morán Rodríguez, Anai Moreno Rodríguez, Zuriñe Ortiz de Zárate, José Joaquín Portu Zapirain, Ester Sáez de Adana Arroniz, Daisy Carolina Sorto Sánchez, Sánchez-Porto Antonio, Úbeda Iglesias Alejandro, José Mª Arribas Leal, Elisa García Vázquez, Alicia Hernández Torres, Ana Blázquez, Gonzalo de la Morena Valenzuela, Ángel Alonso, Javier Aramburu, Felicitas Elena Calvo, Paola Tarabini-Castellani, Eva Heredero Gálvez, Carolina Maicas Bellido, José Largo Pau, Mª Antonia Sepúlveda, Pilar Toledano Sierra, Sadaf Zafar Iqbal-Mirza, Eva Cascales Alcolea, Ivan Keituqwa Yañez, Julián Navarro Martínez, Ana Peláez Ballesta, Eduardo Moreno Escobar, Alejandro Peña Monje, Valme Sánchez Cabrera, David Vinuesa García, María Arrizabalaga Asenjo, Carmen Cifuentes Luna, Juana Núñez Morcillo, Mª Cruz Pérez Seco, Aroa Villoslada Gelabert, Carmen Aured Guallar, Nuria Fernández Abad, Pilar García Mangas, Marta Matamala Adell, Mª Pilar Palacián Ruiz, Juan Carlos Porres, Begoña Alcaraz Vidal, María Jesús Del Amor Espín, Francisco Buendía, Roberto Jiménez Sánchez, Rosario Mármol, Francisco Martínez, Antonio Meseguer, Beatriz Pérez, Leticia Risco, Zoser Saura, Vanina Silva, Mª Belén Villmarín, Mª Ángels Ribas Blanco, Enrique Ruiz de Gopegui Bordes, Laura Vidal Bonet, Miquel Vives Borràs, Mª Carmen Bellón Munera, Elena Escribano Garaizabal, Antonia Tercero Martínez, Juan Carlos Segura Luque, Cristina Badía, Lucía Boix Palop, Mariona Xercavins, Sónia Ibars, Xerach Bosch, Eloy Gómez Nebreda, Ibalia Horcajada Herrera, Irene Menduiña Gallego, Imanol Pulido, Héctor Marrero Santiago, Isabel de Miguel Martínez, Elena Pisos Álamo, Daniel San Román Sánchez, Jorge Boan Pérez, Eva Mª Aguilar Blanco, Mercedes Catalán González, María Angélica Corres Peiretti, Andrea Eixerés Esteve, Laura Domínguez Pérez, Santiago de Cossío Tejido, Francisco Galván Román, José Antonio García Robles, Francisco López Medrano, Mª Jesús López Gude, Mª Ángeles Orellana Miguel, Patrick Pilkington, Yolanda Revilla Ostalaza, Juan Ruiz Morales, Sebastián Ruiz Solís, Ana Sabín Collado, Marcos Sánchez Fernández, Javier Solera Rallo, Jorge Solís Martín, Francesc Escrihuela-Vidal, Jordi Carratalà, Inmaculada Grau, Carmen Ardanuy, Dámaris Berbel, José Carlos Sánchez Salado, Oriol Alegre, Alejandro Ruiz Majoral, Fabrizio Sbraga, Arnau Blasco, Laura Gracia Sánchez, Iván Sánchez-Rodríguez, Gonzalo Aldamiz, Beatriz Álvarez, Marina Bernal Palacios, Alfonso Cabello Úbeda, Ricardo Fernández Roblas, Rafael Hernández, Victoria Andrea Hortigüela Martín, Andrea Kallmeyer, Cristina Landaeta Kancev, Marta Martín, Miguel Morante Ruiz, Miguel Ángel Navas Lobato, Ana María Pello, Laura Prieto, Marta Tomás Mallebrera, Laura Varela, Mireia de la Peña Triguero, Ruth Esther Figueroa Cerón, Lara Ruiz Gómez, Mireia Ble, Juan Pablo Horcajada Gallego, Antonio José Ginel, Inmaculada López, Alexandra Mas, Antoni Mestres, Lluís Molina, Ramón Serrat, Núria Ribas, Francisca Sánchez, Ana Silverio, Marina Suárez, Luisa Sorlí, Lluís Recasens, Manuel Taurón, María Fernández Regueras, María Ángeles Mantecón Vallejo, José Ángel Pérez Rivera, Nuria Sánchez Mata, Antonia Calvo Cano, Miguel Fajardo Olivares, María Victoria Millán Núñez, and Agustín Muñoz Sanz

Subjects
Infective endocarditis, Methicillin-susceptible Staphylococcus aureus, Cefazolin, Antistaphylococcal penicillin, Infectious and parasitic diseases, RC109-216
Abstract

Objectives: This study aimed to assess the real use of cefazolin for methicillin-susceptible Staphylococcus aureus (MSSA) infective endocarditis (IE) in the Spanish National Endocarditis Database (GAMES) and to compare it with antistaphylococcal penicillin (ASP). Methods: Prospective cohort study with retrospective analysis of a cohort of MSSA IE treated with cloxacillin and/or cefazolin. Outcomes assessed were relapse; intra-hospital, overall, and endocarditis-related mortality; and adverse events. Risk of renal toxicity with each treatment was evaluated separately. Results: We included 631 IE episodes caused by MSSA treated with cloxacillin and/or cefazolin. Antibiotic treatment was cloxacillin, cefazolin, or both in 537 (85%), 57 (9%), and 37 (6%) episodes, respectively. Patients treated with cefazolin had significantly higher rates of comorbidities (median Charlson Index 7, P

Published
2023
Full Text
View/download PDF

28. Cloxacillin plus fosfomycin versus cloxacillin alone for methicillin-susceptible Staphylococcus aureus bacteremia: a randomized trial

Author

Grillo, Sara, Pujol, Miquel, Miró, Josep M., López-Contreras, Joaquín, Euba, Gorane, Gasch, Oriol, Boix-Palop, Lucia, Garcia-País, Maria José, Pérez-Rodríguez, Maria Teresa, Gomez-Zorrilla, Silvia, Oriol, Isabel, López-Cortés, Luis Eduardo, Pedro-Botet, Maria Luisa, San-Juan, Rafael, Aguado, José María, Gioia, Francesca, Iftimie, Simona, Morata, Laura, Jover-Sáenz, Alfredo, García-Pardo, Graciano, Loeches, Belén, Izquierdo-Cárdenas, Álvaro, Goikoetxea, Ane Josune, Gomila-Grange, Aina, Dietl, Beatriz, Berbel, Damaris, Videla, Sebastian, Hereu, Pilar, Padullés, Ariadna, Pallarès, Natalia, Tebé, Cristian, Cuervo, Guillermo, and Carratalà, Jordi

Published
2023
Full Text
View/download PDF

31. Magnetic state switching in FeGa microstructures

Author

De Jesus, Michael Guevara, Xiao, Zhuyun, Goiriena-Goikoetxea, Maite, Chopdekar, Rajesh V, Panduranga, Mohanchandra K, Shirazi, Paymon, Acosta, Adrian, Chang, Jane P, Bokor, Jeffrey, Carman, Gregory P, Candler, Rob N, and Lynch, Christopher

Subjects
Engineering, FeGa, micromagnetics, magnetostriction, XMCD-PEEM, piezoelectric, microstructures, modelling, Chemical Sciences, Materials, Chemical sciences
Abstract

This work demonstrates that magnetoelectric composite heterostructures can be designed at the length scale of 10 µms that can be switched from a magnetized state to a vortex state, effectively switching the magnetization off, using electric field induced strain. This was accomplished using thin film magnetoelectric heterostructures of Fe81.4Ga18.6 on a single crystal (011) [Pb(Mg1/3Nb2/3)O3]0.68-[PbTiO3]0.32 (PMN-32PT) ferroelectric substrate. The heterostructures were tripped from a multi-domain magnetized state to a flux closure vortex state using voltage induced strain in a piezoelectric substrate. FeGa heterostructures were deposited on a Si-substrate for superconducting quantum interference device magnetometry characterization of the magnetic properties. The magnetoelectric coupling of a FeGa continuous film on PMN-32PT was characterized using a magneto optical Kerr effect magnetometer with bi-axial strain gauges, and magnetic multi-domain heterostructures were imaged using x-ray magnetic circular dichroism - photoemission electron microscopy during the transition to the vortex state. The domain structures were modelled using MuMax3, a micromagnetics code, and compared with observations. The results provide considerable insight into designing magnetoelectric heterostructures that can be switched from an 'on' state to an 'off' state using electric field induced strain.

Published
2022

32. Substrate matters: Surface-polariton enhanced infrared nanospectroscopy of molecular vibrations

Author

Autore, Marta, Mester, Lars, Goikoetxea, Monika, and Hillenbrand, R.

Subjects
Physics - Optics, Physics - Applied Physics
Abstract

Infrared nanospectroscopy based on Fourier transform infrared near-field spectroscopy (nano-FTIR) is an emerging nanoanalytical tool with large application potential for label-free mapping and identification of organic and inorganic materials with nanoscale spatial resolution. However, the detection of thin molecular layers and nanostructures on standard substrates is still challenged by weak signals. Here, we demonstrate a significant enhancement of nano-FTIR signals of a thin organic layer by exploiting polariton-resonant tip-substrate coupling and surface polariton illumination of the probing tip. When the molecular vibration matches the tip-substrate resonance, we achieve up to nearly one order of magnitude signal enhancement on a phonon-polaritonic quartz (c-SiO2) substrate, as compared to nano-FTIR spectra obtained on metal (Au) substrates, and up to two orders of magnitude when compared to the standard infrared spectroscopy substrate CaF2. Our results will be of critical importance for boosting nano-FTIR spectroscopy towards the routine detection of monolayers and single molecules.

Published
2021
Full Text
View/download PDF

34. Specific and off-target immune responses following COVID-19 vaccination with ChAdOx1-S and BNT162b2 vaccines—an exploratory sub-study of the BRACE trial

Author

Curtis, Nigel, Davidson, Andrew, Gardiner, Kaya, Gwee, Amanda, Jamieson, Tenaya, Messina, Nicole, Morawakage, Thilanka, Perlen, Susan, Perrett, Kirsten, Pittet, Laure, Sastry, Amber, Teo, Jia Wei, Orsini, Francesca, Lee, Katherine, Moore, Cecilia, Vidmar, Suzanna, Ali, Rashida, Dunn, Ross, Edler, Peta, Gell, Grace, Goodall, Casey, Hall, Richard, Krastev, Ann, La, Nathan, McDonald, Ellie, McPhate, Nick, Nguyen, Thao, Ren, Jack, Stevens, Luke, Alamrousi, Ahmed, Bonnici, Rhian, Dang, Thanh, Germano, Susie, Hua, Jenny, McElroy, Rebecca, Razmovska, Monica, Reddiex, Scott, Wang, Xiaofang, Anderson, Jeremy, Azzopardi, Kristy, Bennett-Wood, Vicki, Czajko, Anna, Mazarakis, Nadia, McCafferty, Conor, Oppedisano, Frances, Ortika, Belinda, Pell, Casey, Spry, Leena, Toh, Ryan, Velagapudi, Sunitha, Vlahos, Amanda, Wee-Hee, Ashleigh, Ramos, Pedro, De La Cruz, Karina, Gamage, Dinusha, Karunanayake, Anushka, Mezzetti, Isabella, Ong, Benjamin, Singh, Ronita, Sooriyarachchi, Enoshini, Nicholson, Suellen, Cain, Natalie, Brizuela, Rianne, Huang, Han, Abruzzo, Veronica, Bealing, Morgan, Bimboese, Patricia, Bowes, Kirsty, Burrell, Emma, Chan, Joyce, Cushnahan, Jac, Elborough, Hannah, Elkington, Olivia, Fahey, Kieran, Fernandez, Monique, Flynn, Catherine, Fowler, Sarah, Andrit, Marie Gentile, Gladanac, Bojana, Hammond, Catherine, Ma, Norine, Macalister, Sam, Milojevic, Emmah, Mojeed, Jesutofunmi, Nguyen, Jill, O’Donnell, Liz, Olivier, Nadia, Ooi, Isabelle, Reynolds, Stephanie, Shen, Lisa, Sherry, Barb, Spotswood, Judith, Wedderburn, Jamie, Younes, Angela, Legge, Donna, Bell, Jason, Cheah, Jo, Cobbledick, Annie, Lim, Kee, Elia, Sonja, Addlem, Lynne, Bourke, Anna, Brophy, Clare, Henare, Nadine, Jenkins, Narelle, Machingaifa, Francesca, Miller, Skye, Mitchell, Kirsten, Pitkin, Sigrid, Wall, Kate, Villanueva, Paola, Crawford, Nigel, Norton, Wendy, Tan, Niki, Chengodu, Thilakavathi, Dawson, Diane, Gordon, Victoria, Korman, Tony, O’Bryan, Jess, Agius, Sophie, Bannister, Samantha, Bucholc, Jess, Burns, Alison, Camesella, Beatriz, Carlin, John, Ciaverella, Marianna, Curtis, Maxwell, Firth, Stephanie, Guo, Christina, Hannan, Matthew, Hill, Erin, Joshi, Sri, Lieschke, Katherine, Mathers, Megan, Odoi, Sasha, Rak, Ashleigh, Richards, Chris, Steve, Leah, Stewart, Carolyn, Sudbury, Eva, Thomson, Helen, Watts, Emma, Williams, Fiona, Young, Angela, Glenn, Penny, Kaynes, Andrew, De Floy, Amandine Philippart, Buchanan, Sandy, Sondag, Thijs, Xie, Ivy, Edmund, Harriet, Byrne, Bridie, Keeble, Tom, Ngien, Belle, Noonan, Fran, Wearing-Smith, Michelle, Clarke, Alison, Davies, Pemma, Eastwood, Oliver, Ellinghaus, Alric, Ghieh, Rachid, Hilton, Zahra, Jennings, Emma, Kakkos, Athina, Liang, Iris, Nicol, Katie, O’Callaghan, Sally, Osman, Helen, Rajaram, Gowri, Ratcliffe, Sophia, Rayner, Victoria, Salmon, Ashleigh, Scheppokat, Angela, Stevens, Aimee, Street, Rebekah, Toogood, Nicholas, Wood, Nicholas, Bahaduri, Twinkle, Baulman, Therese, Byrne, Jennifer, Carter, Candace, Corbett, Mary, Dao, Aiken, Desylva, Maria, Dunn, Andrew, Gardiner, Evangeline, Joyce, Rosemary, Kandasamy, Rama, Munns, Craig, Pelayo, Lisa, Sharma, Ketaki, Sterling, Katrina, Uren, Caitlin, Colaco, Clinton, Douglas, Mark, Hamilton, Kate, Bartlett, Adam, McMullan, Brendan, Palasanthiran, Pamela, Williams, Phoebe, Beardsley, Justin, Bergant, Nikki, Lagunday, Renier, Overton, Kristen, Post, Jeffrey, Al-Hindawi, Yasmeen, Barney, Sarah, Byrne, Anthony, Mead, Lee, Plit, Marshall, Lynn, David, Benson, Saoirse, Blake, Stephen, Botten, Rochelle, Chern, Tee Yee, Eden, Georgina, Griffith, Liddy, James, Jane, Lynn, Miriam, Markow, Angela, Sacca, Domenic, Stevens, Natalie, Wesselingh, Steve, Doran, Catriona, Barry, Simone, Sawka, Alice, Evans, Sue, Goodchild, Louise, Heath, Christine, Krieg, Meredith, Marshall, Helen, McMillan, Mark, Walker, Mary, Richmond, Peter, Amenyogbe, Nelly, Anthony, Christina, Arnold, Annabelle, Arrowsmith, Beth, Ben-Othman, Rym, Clark, Sharon, Dunnill, Jemma, Eiffler, Nat, Ewe, Krist, Finucane, Carolyn, Flynn, Lorraine, Gibson, Camille, Hartnell, Lucy, Hollams, Elysia, Hutton, Heidi, Jarvis, Lance, Jones, Jane, Jones, Jan, Jones, Karen, Kent, Jennifer, Kollmann, Tobias, Lalich, Debbie, Lee, Wenna, Lim, Rachel, McAlister, Sonia, McDonald, Fiona, Meehan, Andrea, Minhaj, Asma, Montgomery, Lisa, O’Donnell, Melissa, Ong, Jaslyn, Ong, Joanne, Parkin, Kimberley, Perez, Glady, Power, Catherine, Rezazadeh, Shadie, Richmond, Holly, Rogers, Sally, Schultz, Nikki, Shave, Margaret, Skut, Patrycja, Stiglmayer, Lisa, Truelove, Alexandra, Wadia, Ushma, Wallace, Rachael, Waring, Justin, England, Michelle, Latkovic, Erin, Manning, Laurens, Herrmann, Susan, Lucas, Michaela, Lacerda, Marcus, Andrade, Paulo Henrique, Barbosa, Fabiane Bianca, Barros, Dayanne, Brasil, Larissa, Capella, Ana Greyce, Castro, Ramon, Costa, Erlane, de Souza, Dilcimar, Dias, Maianne, Dias, José, Ferreira, Klenilson, Figueiredo, Paula, Freitas, Thamires, Furtado, Ana Carolina, Gama, Larissa, Godinho, Vanessa, Gouy, Cintia, Hinojosa, Daniele, Jardim, Bruno, Jardim, Tyane, Junior, Joel, Lima, Augustto, Maia, Bernardo, Marins, Adriana, Mazurega, Kelry, Medeiros, Tercilene, Melo, Rosangela, Moraes, Marinete, Nascimento, Elizandra, Neves, Juliana, Oliveira, Maria Gabriela, Oliveira, Thais, Oliveira, Ingrid, Otsuka, Arthur, Paes, Rayssa, Pereira, Handerson, Pereira, Gabrielle, Prado, Christiane, Queiroz, Evelyn, Rodrigues, Laleyska, Rodrigues, Bebeto, Sampaio, Vanderson, Santos, Anna Gabriela, Santos, Daniel, Santos, Tilza, Santos, Evelyn, Sartim, Ariandra, Silva, Ana Beatriz, Silva, Juliana, Silva, Emanuelle, Simão, Mariana, Soares, Caroline, Sousa, Antonny, Trindade, Alexandre, Val, Fernando, Vasconcelos, Adria, Vasconcelos, Heline, Croda, Julio, Abreu, Carolinne, Almeida, Katya Martinez, Bitencourt de Andrade, Camila, Campos Angelo, Jhenyfer Thalyta, Gonçalvez de Araújo Arcanjo, Ghislaine, Silva Menezes Arruda, Bianca Maria, Ayala, Wellyngthon Espindola, Refosco Barbosa, Adelita Agripina, Vieira Batista, Felipe Zampieri, de Morais Batista, Fabiani, de Jesus Costa, Miriam, Croda, Mariana Garcia, Alves da Cruz, Lais, Pereira Diogo, Roberta Carolina, Dutra Escobar, Rodrigo Cezar, Fernandes, Iara Rodrigues, Figueiredo, Leticia Ramires, Cavalcanti Gonçalves, Leandro Galdino, Lahdo, Sarita, Lencina, Joyce dos Santos, Teodoro de Lima, Guilherme, Matos, Larissa Santos, Leopoldina Meireles, Bruna Tayara, Moreira, Debora Quadros, Silva Muranaka, Lilian Batista, de Oliveira, Adriely, Warszawski de Oliveira, Karla Regina, Vieira de Oliveira, Matheus, Dias de Oliveira, Roberto, Souza de Almeida dos Reis Pereira, Andrea Antonia, Puga, Marco, Ramos, Caroliny Veron, Souza da Rosa, Thaynara Haynara, Lopes dos Santos, Karla, Ribeiro dos Santos, Claudinalva, Leopoldina dos Santos, Dyenyffer Stéffany, Santos, Karina Marques, Pereira da Silva, Paulo César, Rocha da Silva, Paulo Victor, Silva, Débora dos Santos, Vieira da Silva, Patricia, Freitas da Rosa Soares, Bruno, Sperotto, Mariana Gazzoni, Tadokoro, Mariana Mayumi, Tsuha, Daniel, Ramos Vieira, Hugo Miguel, Pretti Dalcolmo, Margareth Maria, Lopes Alves da Paixão, Cíntia Maria, Corrêa E Castro, Gabriela, Collopy, Simone Silva, da Costa Silva, Renato, Almeida da Silveira, Samyra, Da-Cruz, Alda Maria, Maria da Silva Passos de Carvalho, Alessandra, de Cássia Batista, Rita, Silva De Freitas, Maria Luciana, Gerhardt de Oliveira Ferreira, Aline, Conceição de Souza, Ana Paula, Doblas, Paola Cerbino, Alcoforado da Silva dos Santos, Ayla, Cristine de Moraes dos Santos, Vanessa, Alves dos Santos Gomes, Dayane, Fortunato, Anderson Lage, Gomes-Silva, Adriano, Gonçalves, Monique Pinto, Garcia Meireless Junior, Paulo Leandro, Martins da Costa Carvalho, Estela, Motta, Fernando do Couto, Olivo de Mendonça, Ligia Maria, Pandine, Girlene dos Santos, Plácido Pereira, Rosa Maria, Maia, Ivan Ramos, Luiz da Rocha, Jorge, Paiva Romano, João Victor, Santos, Glauce dos, Fernandes da Silva, Erica, Mendonça Teixeira de Siqueira, Marilda Agudo, Prudêncio Soares, Ágatha Cristinne, Bonten, Marc, Arroyo, Sandra Franch, Besten, Henny Ophorst-den, Boon, Anna, Brakke, Karin M., Janssen, Axel, Koopmans, Marijke A.H., Lemmens, Toos, Leurink, Titia, Prat-Aymerich, Cristina, Septer-Bijleveld, Engelien, Stadhouders, Kimberly, Troeman, Darren, van der Waal, Marije, van Opdorp, Marjoleine, van Sluis, Nicolette, Wolters, Beatrijs, Kluytmans, Jan, Romme, Jannie, van den Bijllaardt, Wouter, van Mook, Linda, Rijen, M.M.L (Miranda) van, Filius, Margreet, Gisolf, Jet, Greven, Frances, Huijbens, Danique, Hassing, Robert Jan, Pon, Roos, Preijers, Lieke, van Leusen, Joke, Verheij, Harald, Boersma, Wim, Brans, Evelien, Kloeg, Paul, Molenaar-Groot, Kitty, Nguyen, Nhat Khanh, Paternotte, Nienke, Rol, Anke, Stooper, Lida, Dijkstra, Helga, Eggenhuizen, Esther, Huijs, Lucas, Moorlag, Simone, Netea, Mihai, Pranger, Eva, Taks, Esther, Oever, Jaap ten, Heine, Rob ter, Blauwendraat, Kitty, Meek, Bob, Erkaya, Isil, Harbech, Houda, Roescher, Nienke, Peeters, Rifka, Riele, Menno te, Zhou, Carmen, Calbo, Esther, Marti, Cristina Badia, Palomares, Emma Triviño, Porcuna, Tomás Perez, Barriocanal, Anabel, Barriocanal, Ana Maria, Casas, Irma, Dominguez, Jose, Esteve, Maria, Lacoma, Alicia, Latorre, Irene, Molina, Gemma, Molina, Barbara, Rosell, Antoni, Vidal, Sandra, Barrera, Lydia, Bustos, Natalia, Calderón, Ines Portillo, Campos, David Gutierrez, Carretero, Jose Manuel, Castellano, Angel Dominguez, Compagnone, Renato, Ramirez de Arellano, Encarnacion, Serna, Almudena de la, Dolores del Toro Lopez, Maria, Clement Espindola, Marie-Alix, Martin Gutierrez, Ana Belen, Hernandez, Alvaro Pascual, Jiménez, Virginia Palomo, Moreno, Elisa, Navarrete, Nicolas, Paño, Teresa Rodriguez, Rodríguez-Baño, Jesús, Tristán, Enriqueta, Rios Villegas, Maria Jose, Garces, Atsegiñe Canga, Amo, Erika Castro, Guerrero, Raquel Coya, Goikoetxea, Josune, Jorge, Leticia, Perez, Cristina, Fariñas Álvarez, María Carmen, Cuadra, Manuel Gutierrez, Arnaiz de las Revillas Almajano, Francisco, Garcia, Pilar Bohedo, Poderos, Teresa Giménez, Rico, Claudia González, Sanchez, Blanca, Valero, Olga, Vega, Noelia, Campbell, John, Barnes, Anna, Catterick, Helen, Cranston, Tim, Dawe, Phoebe, Fletcher, Emily, Fouracre, Liam, Gifford, Alison, Kirkwood, John, Martin, Christopher, McAnew, Amy, Mitchell, Marcus, Newman, Georgina, O’Connell, Abby, Onysk, Jakob, Quinn, Lynne, Rhodes, Shelley, Stone, Samuel, Symons, Lorrie, Tripp, Harry, Warris, Adilia, Watkins, Darcy, Whale, Bethany, Harding, Alex, Lockhart, Gemma, Sidaway-Lee, Kate, Hilton, Sam, Manton, Sarah, Webber-Rookes, Daniel, Winder, Rachel, Moore, James, Bateman, Freya, Gibbons, Michael, Knight, Bridget, Moss, Julie, Statton, Sarah, Studham, Josephine, Hall, Lydia, Moyle, Will, Venton, Tamsin, Messina, Nicole L., Grubor-Bauk, Branka, Lynn, David J., Perrett, Kirsten P., Pittet, Laure F., Rudraraju, Rajeev, Stevens, Natalie E., and Subbarao, Kanta

Published
2024
Full Text
View/download PDF

36. Whole-genome characterisation of Escherichia coli isolates from patients with bacteraemia presenting with sepsis or septic shock in Spain: a multicentre cross-sectional study

Author

Maldonado, Natalia, López-Hernández, Inmaculada, García-Montaner, Andrea, López-Cortés, Luis Eduardo, Pérez-Crespo, Pedro María Martínez, Retamar-Gentil, Pilar, Sousa-Domínguez, Adrián, Goikoetxea, Josune, Pulido-Navazo, Ángeles, Labayru-Echeverría, Cristina, Natera-Kindelán, Clara, Jover-Sáenz, Alfredo, del Arco-Jiménez, Alfonso, Armiñanzas-Castillo, Carlos, Aller, Ana Isabel, Fernández-Suárez, Jonathan, Marrodán-Ciordia, Teresa, Boix-Palop, Lucía, Smithson-Amat, Alejandro, Reguera-Iglesias, José Mª, Galán-Sánchez, Fátima, Bahamonde, Alberto, Sánchez Calvo, Juan Manuel, Gea-Lázaro, Isabel, Pérez-Camacho, Inés, Reyes-Bertos, Armando, Becerril-Carral, Berta, Rodríguez-Baño, Jesús, and Pascual, Álvaro

Published
2024
Full Text
View/download PDF

37. Efficacy and safety of a structured de-escalation from antipseudomonal β-lactams in bloodstream infections due to Enterobacterales (SIMPLIFY): an open-label, multicentre, randomised trial

Author

De Cueto, Marina, Borreguero, Irene, Nieto Aranda, Javier, Sousa Domínguez, Adrián, González-Rico, Claudia, Fariñas, María Carmen, Fernández Ávila, María Luisa, Romero Palacios, Alberto, Guerrero Sánchez, Francisca María, Rúa Gómez, Marta, Bilbao del Olmo, Idoia, Calbo, Esther, Dietl, Beatriz, Ibarguren Pinilla, Maialen, Gómez-Ruiz de Arbulo, Marta, Torres Beceiro, Isabel, Machuca, Isabel, Cano, Ángela, Giner Oncina, Livia, Pinargote Celorio, Héctor, Cendejas, Emilio, Romero Gómez, María, Argüelles Curto, Adrián, Reguero, José María, Díaz-López, María Dolores, Paño, José Ramón, López-Cortés, Luis Eduardo, Delgado-Valverde, Mercedes, Moreno-Mellado, Elisa, Goikoetxea Aguirre, Josune, Guio Carrión, Laura, Blanco Vidal, María José, López Soria, Leyre Mónica, Pérez-Rodríguez, María Teresa, Martínez Lamas, Lucía, Arnaiz de las Revillas, Francisco, Armiñanzas, Carlos, Ruiz de Alegría-Puig, Carlos, Jiménez Aguilar, Patricia, del Carmen Martínez-Rubio, María, Sáez-Bejar, Carmen, de las Cuevas, Carmen, Martín-Aspas, Andrés, Galán, Fátima, Yuste, José Ramón, Leiva-León, José, Bou, Germán, Capón González, Patricia, Boix-Palop, Lucía, Xercavins-Valls, Mariona, Goenaga-Sánchez, Miguel Ángel, Anza, Diego Vicente, Castón, Juan José, Rufián, Manuel Recio, Merino, Esperanza, Rodríguez, Juan Carlos, Loeches, Belén, Cuervo, Guillermo, Guerra Laso, José Manuel, Plata, Antonio, Pérez Cortés, Salvador, López Mato, Pablo, Sierra Monzón, José Luis, Rosso-Fernández, Clara, Bravo-Ferrer, José María, Retamar-Gentil, Pilar, and Rodríguez-Baño, Jesús

Published
2024
Full Text
View/download PDF

38. SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer

Author

Lachiondo-Ortega, Sofia, Rejano-Gordillo, Claudia M., Simon, Jorge, Lopitz-Otsoa, Fernando, C. Delgado, Teresa, Mazan-Mamczarz, Krystyna, Goikoetxea-Usandizaga, Naroa, Zapata-Pavas, L. Estefanía, García-del Río, Ana, Guerra, Pietro, Peña-Sanfélix, Patricia, Hermán-Sánchez, Natalia, Al-Abdulla, Ruba, Fernandez-Rodríguez, Carmen, Azkargorta, Mikel, Velázquez-Cruz, Alejandro, Guyon, Joris, Martín, César, Zalamea, Juan Diego, Egia-Mendikute, Leire, Sanz-Parra, Arantza, Serrano-Maciá, Marina, González-Recio, Irene, Gonzalez-Lopez, Monika, Martínez-Cruz, Luis Alfonso, Pontisso, Patrizia, Aransay, Ana M., Barrio, Rosa, Sutherland, James D., Abrescia, Nicola G.A., Elortza, Félix, Lujambio, Amaia, Banales, Jesus M., Luque, Raúl M., Gahete, Manuel D., Palazón, Asís, Avila, Matias A., G. Marin, Jose J., De, Supriyo, Daubon, Thomas, Díaz-Quintana, Antonio, Díaz-Moreno, Irene, Gorospe, Myriam, Rodríguez, Manuel S., and Martínez-Chantar, María Luz

Published
2024
Full Text
View/download PDF

39. Análisis comparativo de un corpus de videojuegos traducidos por traductores profesionales y voluntarios

Author

Itziar Zorrakin-Goikoetxea

Subjects
Videojuegos, Localización, Traducción audiovisual, Corpus multimodal, Voluntarios, Translating and interpreting, P306-310
Abstract

Un gran número de videojuegos, especialmente los desarrollados por empresas indie, son traducidos por traductores voluntarios sin formación en traducción. Las repercusiones de esta práctica aún no han sido estudiadas en profundidad y este artículo se propone contribuir a ahondar en las diferencias en los videojuegos localizados en función del tipo de proveedor de la traducción. A través de una encuesta a los desarrolladores de 172 videojuegos, se han confirmado datos como el tipo de traductor o el nivel de revisión y, gracias a dichos datos, se ha construido un corpus multimodal de cuatro videojuegos traducidos por profesionales (con mayor o menor nivel de revisión y control de calidad) y dos videojuegos traducidos por voluntarios. Los datos preliminares y el estudio macroestructural del corpus han revelado en qué contexto se localizaron los videojuegos, así como que no se realizaron cambios más allá de la subtitulación y/o doblaje del discurso escrito u oral (no hubo cambios ni en la música de fondo ni en los iconos gráficos, independientemente del tipo de traductor). El estudio microestructural, a su vez, ha destacado diferencias lingüísticas entre los videojuegos, siendo aquellos traducidos por voluntarios los que más errores presentan. En el corpus analizado, el subgrupo de los videojuegos traducidos por voluntarios presenta hasta siete veces más fenómenos perceptibles por el jugador final que el subgrupo traducido por profesionales con un proceso de localización más exhaustivo.

Published
2024
Full Text
View/download PDF

40. Mobile App/Web Platform for Monitoring Food Oral Immunotherapy in Children: Longitudinal Clinical Validation Study

Author

Sergio Sánchez-Fernández, Eva María Lasa, Soledad Terrados, Francisco Javier Sola-Martínez, Sara Martínez-Molina, Marta López de Calle, Paula Cabrera-Freitag, and María José Goikoetxea

Subjects
Pediatrics, RJ1-570
Abstract

BackgroundMilk and egg allergies significantly impact the quality of life, particularly in children. In this regard, food oral immunotherapy (OIT) has emerged as an effective treatment option; however, the occurrence of frequent adverse reactions poses a challenge, necessitating close monitoring during treatment. ObjectiveThis study aims to evaluate the ability of a new mobile/web app called OITcontrol to monitor milk and egg OIT. MethodsPatients undergoing milk or egg OIT were recruited and divided into 2 groups: the active group used the OITcontrol app in conjunction with standard written monitoring methods, whereas the control group relied solely on written diaries. Investigators documented hospital doses, hospital reactions, and administered treatments on the website. Patients recorded their daily allergen home-dose intake, home reactions, and administered treatments using the app. The following variables were compared between both groups: number and severity of hospital and reported home reactions, patient’s adhesion to the OITcontrol app or written diary or both in terms of daily home-dose intake and home reactions recording, and treatment and dose adjustment compliance at home in case of reaction. ResultsSixteen patients were assigned to be monitored using the OITcontrol app along with additional written methods (active group), while 14 patients relied solely on a written paper diary (control group). A similar distribution was observed in terms of sex, age, basal characteristics, allergen treated in OIT, premedication, and sensitization profile. Active patients reported a comparable number of hospital and home reactions compared with the control group. In terms of recording system usage, 13/16 (81%) active patients used the OITcontrol app, while 10/14 (71%) control patients relied on the written diary. Among active patients, 6/16 (38%) used both methods, and 1 active patient used only written methods. However, control patients recorded home reactions more frequently than active patients (P=.009). Among active patients, the app was the preferred method for recording reactions (59/86, 69%), compared with the written diary (15/86, 17%) or both methods (12/86, 14%; P

Published
2024
Full Text
View/download PDF

41. The Wireless Train Communication Network: Roll2Rail vision

Author

García-Loygorri, Juan Moreno, Goikoetxea, Javier, Echeverría, Eneko, Arriola, Aitor, Val, Iñaki, Sand, Stephan, Unterhuber, Paul, and del Río, Francisco

Subjects
Computer Science - Networking and Internet Architecture
Abstract

This paper explains the main results obtained from the research carried out in the work package 2 (WP2) of the Roll2Rail (R2R) project. This project aims to develop key technologies and to remove already identified blocking points for radical innovation in the field of railway vehicles, to increase their operational reliability and to reduce life-cycle costs. This project started in May 2015 and has been funded by the Horizon 2020 program of the European Commission. The goal for WP2 is to research on both technologies and architectures to develop a new wireless Train Communication Network (TCN) within IEC61375 standard series. This TCN is today entirely wired and is used for Train Control and Monitoring System (TCMS) functions (some of them safetyrelated), operator-oriented services and customer-oriented services. This paradigm shift from wired to wireless means a removal of wirings implies, among other benefits, a significant reduction of life cycle costs due to the removal of cables, and the simplification of the train coupling procedure, among others.

Published
2020

42. Rapid infrared spectroscopic nano-imaging with nano-FTIR holography

Author

Schnell, Martin, Goikoetxea, Monika, Amenabar, Iban, Carney, P. Scott, and Hillenbrand, Rainer

Subjects
Physics - Optics
Abstract

Scattering-type scanning near-field optical microscopy (s-SNOM), and its derivate, Fourier transform infrared nanospectroscopy (nano-FTIR) are emerging techniques for infrared (IR) nanoimaging and spectroscopy with applications in diverse fields ranging from nanophotonics, chemical imaging and materials science. However, spectroscopic nanoimaging is still challenged by the limited acquisition rate of current nano-FTIR technology. Here we combine s-SNOM, nano-FTIR and synthetic optical holographic (SOH) to achieve infrared spectroscopic nanoimaging at unprecedented speed (8 spectroscopically resolved images in 20 min), which we demonstrate with a polymer composite sample. Beyond being fast, our method promises to enable nanoimaging in the long IR spectral range, which is covered by IR supercontinuum and synchrotron sources, but not by current quantum cascade laser technology., Comment: 17 pages, 4 figures, plus supplementary information

Published
2020
Full Text
View/download PDF

44. State-of-the-Art in Language Technology and Language-centric Artificial Intelligence

Author

Agerri, Rodrigo, Agirre, Eneko, Aldabe, Itziar, Aranberri, Nora, Arriola, Jose Maria, Atutxa, Aitziber, Azkune, Gorka, Campos, Jon Ander, Casillas, Arantza, Estarrona, Ainara, Farwell, Aritz, Goenaga, Iakes, Goikoetxea, Josu, Gojenola, Koldo, Hernáez, Inma, Iruskieta, Mikel, Labaka, Gorka, Lacalle, Oier Lopez de, Navas, Eva, Oronoz, Maite, Otegi, Arantxa, Pérez, Alicia, Viñaspre, Olatz Perez de, Rigau, German, Salaberria, Ander, Sanchez, Jon, Saratxaga, Ibon, Soroa, Aitor, Sonntag, Daniel, Editor-in-Chief, Rehm, Georg, editor, and Way, Andy, editor

Published
2023
Full Text
View/download PDF

46. Mortality predictors and definition proposal for complicated coagulase-negative Staphylococcus bacteraemia: a multicentre prospective cohort study

Author

Varisco, Benedetta, Martínez Pérez-Crespo, Pedro María, Retamar-Gentil, Pilar, Hernandez, Inmaculada López, Fariñas-Álvarez, Maria Carmen, Fernández-Natal, Isabel, Pérez-Rodríguez, María Teresa, Goikoetxea Aguirre, Ane Josune, Sánchez-Calvo, Juan Manuel, Martín, Luis Buzón, León-Jiménez, Eva, García, David Vinuesa, Reguera-Iglesias, José María, Bahamonde-Carrasco, Alberto, Suárez, Jonathan Fernández, Rodríguez-Baño, Jesús, and López-Cortés, Luis Eduardo

Published
2024
Full Text
View/download PDF

47. Ceftaroline for bloodstream infections caused by methicillin-resistant Staphylococcus aureus: a multicentre retrospective cohort study

Author

Berbel, Damaris, Campany, David, Rio, Lara del, Eworo, Alia, Ferrando, Valeria, García-Tellado, Alex, Grau, Inmaculada, Guerra-Laso, José Manuel, Rodríguez, Sara, Roig-Sanchis, Joan, Sánchez-Martínez, Celia, Viñado, Belén, Urbina, Luciana, Halperin, Ana V., Xercavins, Mariona, Villa, Sofía de la, Escrihuela-Vidal, Francesc, Fernández-Hidalgo, Nuria, Escudero-Sánchez, Rosa, Cabezón, Itxasne, Boix-Palop, Lucía, Díaz-Pollán, Beatriz, Goikoetxea, Ane Josune, García-País, María José, Pérez-Rodríguez, María Teresa, Crespo, Ángela, Buzón-Martín, Luis, Sanz-Peláez, Oscar, Ramos-Merino, Lucía, Silvante, Fiorana, and Muñoz, Patricia

Published
2024
Full Text
View/download PDF

48. Anti-miR-873-5p improves alcohol-related liver disease by enhancing hepatic deacetylation via SIRT1

Author

Rodríguez-Agudo, Rubén, González-Recio, Irene, Serrano-Maciá, Marina, Bravo, Miren, Petrov, Petar, Blaya, Delia, Herranz, Jose María, Mercado-Gómez, María, Rejano-Gordillo, Claudia María, Lachiondo-Ortega, Sofía, Gil-Pitarch, Clàudia, Azkargorta, Mikel, Van Liempd, Sebastiaan Martijn, Martinez-Cruz, Luis Alfonso, Simão, A.L., Elortza, Félix, Martín, César, Nevzorova, Yulia A., Cubero, Francisco Javier, Delgado, Teresa C., Argemi, Josepmaria, Bataller, Ramón, Schoonjans, Kristina, Banales, Jesús M., Castro, Rui E., Sancho-Bru, Pau, Avila, Matías A., Julve, Josep, Jover, Ramiro, Mabe, Jon, Simon, Jorge, Goikoetxea-Usandizaga, Naroa, and Martínez-Chantar, María L.

Published
2024
Full Text
View/download PDF

49. Effectiveness and Safety of Direct-acting Antivirals for Treatment of Adolescents With HCV/HIV Coinfection: Real-world Data From Europe

Author

Malik, Farihah, Crichton, Siobhan, Plotnikova, Yulia, Latysheva, Inga, Samarina, Anna, Pokorska-Śpiewak, Maria, Gomez, Marisa Navarro, Bailey, Heather, Thorne, Claire, Judd, Ali, Turkova, Anna, Collins, Intira Jeannie, Marczyńska, Magdalena, Popielska, Jolanta, Ołdakowska, Agnieszka, Zawadka, Konrad, Pluta, Magdalena, Doroba, Małgorzata, Okhonskaya, Liubov, Rozenberg, Vladimir, Voronin, Evgeny, Plynsky, Alexksey A., José Mellado, María, Escosa, Luis, García Hortelano, Milagros, Sainz, Talía, Grasa, Carlos, Rodríguez, Paula, Rojo, Pablo, Prieto-Tato, Luis, Epalza, Cristina, Tagarro, Alfredo, Domínguez, Sara, Ballesteros, Álvaro, Tomás Ramos, José, Illán, Marta, Berzosa, Arantxa, Guillén, Sara, Soto, Beatriz, Luisa Navarro, María, Saavedra, Jesús, Santos, Mar, Aguilera, David, Santiago, Begoña, Jimenez de Ory, Santiago, Bermejo, Amanda, Penín, María, Martínez, Jorge, Badillo, Katie, Belén Jiménez, Ana, Navas, Adriana, Oñate, Eider, Pocheville, Itziar, Garrote, Elisa, Colino, Elena, Afonso, Olga, Gómez Sirvent, Jorge, Garzón, Mónica, Román, Vicente, Angulo, Raquel, Neth, Olaf, Falcón, Lola, Terol, Pedro, Luis Santos, Juan, Vázquez, Álvaro, Carazo, Begoña, Medina, Antonio, Lendínez, Francisco, Ibáñez, Mercedes, Peromingo, Estrella, Isabel Sánchez, María, Ruiz, Beatriz, Grande, Ana, José Romero, Francisco, Pérez, Carlos, Calle, Laura, Pareja, Marta, Losada, Begoña, Herranz, Mercedes, Bustillo, Matilde, Collado, Pilar, Antonio Couceiro, José, Vila, Leticia, Calviño, Consuelo, Isabel Piqueras, Ana, Oltra, Manuel, Gavilán, César, Montesinos, Elena, Dapena, Marta, Jiménez, Beatriz, Gloria Andrés, Ana, Marugán, Víctor, Ochoa, Carlos, Isabel Menasalvas, Ana, Cervantes, Eloísa, Álvarez, Beatriz, Díez, Cristina, Bernardino, Ignacio, Luisa Montes, María, Valencia, Eulalia, Delgado, Ana, Rubio, Rafael, Pulido, Federico, Bisbal, Otilia, Monereo Alonso, Alfonso, Berenguer, Juan, Díez, Cristina, Aldamiz, Teresa, Tejerina, Francisco, Carlos Bernaldo de Quirós, Juan, Padilla, Belén, Carrillo, Raquel, Montilla, Pedro, Bermúdez, Elena, Valerio, Maricela, Sanz, Jose, Gimeno, Alejandra, Cervero, Miguel, Torres, Rafael, Moreno, Santiago, Jesús Perez, María, del Campo, Santos, Ryan, Pablo, Troya, Jesus, Sanz, Jesus, Losa, Juan, Gomez, Rafael, Górgolas, Miguel, Díaz, Alberto, de la Fuente, Sara, Antonio Iribarren, Jose, Jose Aramburu, Maria, Martinez, Lourdes, Josune Goikoetxea, Ane, Ibarra, Sofia, de la Peña, Mireia, Asensi, Víctor, Hernandez, Michele, Remedios Alemán, María, Pelazas, Ricardo, del Mar Alonso, María, María López, Ana, García, Dácil, Rodriguez, Jehovana, Angel Cardenes, Miguel, Castaño, Manuel A., Orihuela, Francisco, Pérez, Inés, Isabel Mayorga, Mª, Fernando Lopez-Cortes, Luis, Roca, Cristina, Llaves, Silvia, Jose Rios, Maria, Rodriguez, Jesus, Palomo, Virginia, Pasquau, Juan, Garcia, Coral, Hernandez, Jose, Martinez, Clara, Rivero, Antonio, Camacho, Angela, Merino, Dolores, Raffo, Miguel, Corpa, Laura, Martinez, Elisa, Mateos, Fernando, Javier Blanch, Jose, Torralba, Miguel, Arazo, Piedad, Samperiz, Gloria, Miralles, Celia, Ocampo, Antonio, Pousada, Guille, Mena, Alvaro, Montero, Marta, Salavert, Miguel, Jose Galindo, Maria, Pretel, Natalia, Portilla, Joaquín, Portilla, Irene, Gutierrez, Felix, Masia, Mar, Robledano, Cati, Adsuar, Araceli, Hinojosa, Carmen, Monteagudo, Begoña, Bachiller, Pablo, Abadía, Jesica, Galera, Carlos, Albendin, Helena, Fernandez, Marian, and Ramon Blanco, Jose

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results