105 results on '"Girardin, Marc"'
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2. Impact of Overweight and Obesity on Disease Outcome in the Pediatric Swiss Inflammatory Bowel Disease Cohort
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von Graffenried, Thea, Schoepfer, Alain M., Rossel, Jean-Benoit, Greuter, Thomas, Safroneeva, Ekaterina, Godat, Sébastien, Henchoz, Sarah, Vavricka, Stephan R., Sokollik, Christiane, Spalinger, Johannes, Braegger, Christian P., Nydegger, Andreas, Abdelrahman, Karim, Ademi, Gentiana, Aepli, Patrick, Thomas, Amman, Anderegg, Claudia, Antonino, Anca-Teodora, Archanioti, Eva, Arrigoni, Eviano, de Jong, Diana Bakker, Balsiger, Bruno, Bastürk, Polat, Bauerfeind, Peter, Becocci, Andrea, Belli, Dominique, Bengoa, José M., Biedermann, Luc, Binek, Janek, Blattmann, Mirjam, Boehm, Stephan, Boldanova, Tujana, Borovicka, Jan, Braegger, Christian P., Brand, Stephan, Brügger, Lukas, Brunner, Simon, Bühr, Patrick, Burnand, Bernard, Burk, Sabine, Burri, Emanuel, Buyse, Sophie, Cao, Dahlia-Thao, Carstens, Ove, Criblez, Dominique H., Cunningham, Sophie, D’Angelo, Fabrizia, de Saussure, Philippe, Degen, Lukas, Delarive, Joakim, Doerig, Christopher, Dora, Barbara, Drerup, Susan, Egger, Mara, El-Wafa, Ali, Engelmann, Matthias, Felley, Christian, Fliegner, Markus, Fournier, Nicolas, Fraga, Montserrat, Franc, Yannick, Frei, Pascal, Frei, Remus, Fried, Michael, Froehlich, Florian, Furlano, Raoul Ivano, Garzoni, Luca, Geyer, Martin, Girard, Laurent, Girardin, Marc, Golay, Delphine, Good, Ignaz, Bigler, Ulrike Graf, Gysi, Beat, Haarer, Johannes, Halama, Marcel, Haldemann, Janine, Heer, Pius, Heimgartner, Benjamin, Helbling, Beat, Hengstler, Peter, Herzog, Denise, Hess, Cyrill, Heyland, Klaas, Hinterleitner, Thomas, Hirschi, Claudia, Hruz, Petr, Juillerat, Pascal, Khalid-de Bakker, Carolina, Kayser, Stephan, Keller, Céline, Knellwolf, Christina, Knoblauch, Christoph, Köhler, Henrik, Koller, Rebekka, Krieger, Claudia, Künzler, Patrizia, Kusche, Rachel, Lehmann, Frank Serge, Macpherson, Andrew, Maillard, Michel H., Manz, Michael, Marot, Astrid, Meier, Rémy, Meyenberger, Christa, Meyer, Pamela, Michetti, Pierre, Misselwitz, Benjamin, Mosler, Patrick, Mottet, Christian, Müller, Christoph, Müllhaupt, Beat, Musso, Leilla, Neagu, Michaela, Nichita, Cristina, Niess, Jan, Nydegger, Andreas, Obialo, Nicole, Ollo, Diana, Oropesa, Cassandra, Peter, Ulrich, Peternac, Daniel, Petit, Laetitia Marie, Pittet, Valérie, Pohl, Daniel, Porzner, Marc, Preissler, Claudia, Raschle, Nadia, Rentsch, Ronald, Restellini, Alexandre, Restellini, Sophie, Richterich, Jean-Pierre, Ris, Frederic, Risti, Branislav, Ritz, Marc Alain, Rogler, Gerhard, Röhrich, Nina, Rossel, Jean-Benoît, Rueger, Vanessa, Rusticeanu, Monica, Sagmeister, Markus, Saner, Gaby, Sauter, Bernhard, Sawatzki, Mikael, Scharl, Michael, Schelling, Martin, Schibli, Susanne, Schlauri, Hugo, Schluckebier, Dominique, Schmid, Daniela, Schmid, Sybille, Schnegg, Jean-François, Schoepfer, Alain, Seematter, Vivianne, Seibold, Frank, Seirafi, Mariam, Semadeni, Gian-Marco, Senning, Arne, Sokollik, Christiane, Sommer, Joachim, Spalinger, Johannes, Spangenberger, Holger, Stadler, Philippe, Staub, Peter, Staudenmann, Dominic, Stenz, Volker, Steuerwald, Michael, Straumann, Alex, Stulz, Andreas, Sulz, Michael, Tatu, Aurora, Tempia-Caliera, Michela, Thorens, Joël, Truninger, Kaspar, Tutuian, Radu, Urfer, Patrick, Vavricka, Stephan, Viani, Francesco, Vögtlin, Jürg, Von Känel, Roland, Vouillamoz, Dominique, Vulliamy, Rachel, Wiesel, Paul, Wiest, Reiner, Wöhrle, Stefanie, Zamora, Samuel, Zander, Silvan, Zeitz, Jonas, and Zimmermann, Dorothee
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- 2022
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3. Differences in Outcomes Reported by Patients With Inflammatory Bowel Diseases vs Their Health Care Professionals
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Anderegg, Claudia, Bauerfeind, Peter, Beglinger, Christoph, Begré, Stefan, Belli, Dominique, Bengoa, José M., Biedermann, Luc, Bigler, Beat, Binek, Janek, Blattmann, Mirjam, Boehm, Stephan, Borovicka, Jan, Braegger, Christian P., Brunner, Nora, Bühr, Patrick, Burnand, Bernard, Burri, Emanuel, Buyse, Sophie, Cremer, Matthias, Criblez, Dominique H., de Saussure, Philippe, Degen, Lukas, Delarive, Joakim, Doerig, Christopher, Dora, Barbara, Dorta, Gian, Egger, Mara, Ehmann, Tobias, El-Wafa, Ali, Engelmann, Matthias, Ezri, Jessica, Felley, Christian, Fliegner, Markus, Fournier, Nicolas, Fraga, Montserrat, Frei, Pascal, Frei, Remus, Fried, Michael, Froehlich, Florian, Funk, Christian, Furlano, Raoul Ivano, Gallot-Lavallée, Suzanne, Geyer, Martin, Girardin, Marc, Golay, Delphine, Grandinetti, Tanja, Gysi, Beat, Haack, Horst, Haarer, Johannes, Helbling, Beat, Hengstler, Peter, Herzog, Denise, Hess, Cyrill, Heyland, Klaas, Hinterleitner, Thomas, Hiroz, Philippe, Hirschi, Claudia, Hruz, Petr, Iwata, Rika, Jost, Res, Juillerat, Pascal, Keller, Céline, Knellwolf, Christina, Knoblauch, Christoph, Köhler, Henrik, Koller, Rebekka, Krieger-Grübel, Claudia, Kullak-Ublick, Gerd, Künzler, Patrizia, Landolt, Markus, Lange, Rupprecht, Lehmann, Frank Serge, Macpherson, Andrew, Maerten, Philippe, Maillard, Michel H., Manser, Christine, Manz, Michael, Marbet, Urs, Marx, George, Matter, Christoph, Meier, Rémy, Mendanova, Martina, Michetti, Pierre, Misselwitz, Benjamin, Morell, Bernhard, Mosler, Patrick, Mottet, Christian, Müller, Christoph, Müller, Pascal, Müllhaupt, Beat, Münger-Beyeler, Claudia, Musso, Leilla, Nagy, Andreas, Neagu, Michaela, Nichita, Cristina, Niess, Jan, Nydegger, Andreas, Obialo, Nicole, Oneta, Carl, Oropesa, Cassandra, Peter, Ueli, Peternac, Daniel, Petit, Laetitia Marie, Piccoli-Gfeller, Franziska, Pilz, Julia Beatrice, Pittet, Valérie, Raschle, Nadia, Rentsch, Ronald, Restellini, Sophie, Richterich, Jean-Pierre, Rihs, Sylvia, Ritz, Marc Alain, Roduit, Jocelyn, Rogler, Daniela, Rogler, Gerhard, Rossel, Jean-Benoît, Rueger, Vanessa, Saner, Gaby, Sauter, Bernhard, Sawatzki, Mikael, Schäppi, Michela, Scharl, Michael, Scharl, Sylvie, Schelling, Martin, Schibli, Susanne, Schlauri, Hugo, Uebelhart, Sybille Schmid, Schnegg, Jean-François, Schoepfer, Alain, Seibold, Frank, Seirafi, Mariam, Semadeni, Gian-Marco, Semela, David, Senning, Arne, Sidler, Marc, Sokollik, Christiane, Spalinger, Johannes, Spangenberger, Holger, Stadler, Philippe, Steuerwald, Michael, Straumann, Alex, Straumann-Funk, Bigna, Sulz, Michael, Suter, Alexandra, Thorens, Joël, Tiedemann, Sarah, Tutuian, Radu, Vavricka, Stephan, Viani, Francesco, Vögtlin, Jürg, Von Känel, Roland, Vonlaufen, Alain, Vouillamoz, Dominique, Vulliamy, Rachel, Wermuth, Jürg, Werner, Helene, Wiesel, Paul, Wiest, Reiner, Wylie, Tina, Zeitz, Jonas, Zimmermann, Dorothee, Pittet, Valérie E.H., and Simonson, Thomas
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- 2019
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4. Tele-Promotion Rurale, Rhone-Alpes, Auvergne, France
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Girardin, Marc, primary
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- 2018
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5. Symptoms of Depression and Anxiety Are Independently Associated With Clinical Recurrence of Inflammatory Bowel Disease
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Anderegg, Claudia, Bauerfeind, Peter, Beglinger, Christoph, Begré, Stefan, Belli, Dominique, Bengoa, José M., Biedermann, Luc, Bigler, Beat, Binek, Janek, Blattmann, Mirjam, Boehm, Stephan, Borovicka, Jan, Braegger, Christian P., Brunner, Nora, Bühr, Patrick, Burnand, Bernard, Burri, Emanuel, Buyse, Sophie, Cremer, Matthias, Criblez, Dominique H., de Saussure, Philippe, Degen, Lukas, Delarive, Joakim, Doerig, Christopher, Dora, Barbara, Dorta, Gian, Egger, Mara, Ehmann, Tobias, El-Wafa, Ali, Engelmann, Matthias, Ezri, Jessica, Felley, Christian, Fliegner, Markus, Fournier, Nicolas, Fraga, Montserrat, Frei, Pascal, Frei, Remus, Fried, Michael, Froehlich, Florian, Funk, Christian, Ivano Furlano, Raoul, Gallot-Lavallée, Suzanne, Geyer, Martin, Girardin, Marc, Golay, Delphine, Grandinetti, Tanja, Gysi, Beat, Haack, Horst, Haarer, Johannes, Helbling, Beat, Hengstler, Peter, Herzog, Denise, Hess, Cyrill, Heyland, Klaas, Hinterleitner, Thomas, Hiroz, Philippe, Hirschi, Claudia, Hruz, Petr, Iwata, Rika, Jost, Res, Juillerat, Pascal, Kessler Brondolo, Vera, Knellwolf, Christina, Knoblauch, Christoph, Köhler, Henrik, Koller, Rebekka, Krieger-Grübel, Claudia, Kullak-Ublick, Gerd, Künzler, Patrizia, Landolt, Markus, Lange, Rupprecht, Serge Lehmann, Frank, Macpherson, Andrew, Maerten, Philippe, Maillard, Michel H., Manser, Christine, Manz, Michael, Marbet, Urs, Marx, George, Matter, Christoph, McLin, Valérie, Meier, Rémy, Mendanova, Martina, Meyenberger, Christa, Michetti, Pierre, Misselwitz, Benjamin, Moradpour, Darius, Morell, Bernhard, Mosler, Patrick, Mottet, Christian, Müller, Christoph, Müller, Pascal, Müllhaupt, Beat, Münger-Beyeler, Claudia, Musso, Leilla, Nagy, Andreas, Neagu, Michaela, Nichita, Cristina, Niess, Jan, Noël, Natacha, Nydegger, Andreas, Obialo, Nicole, Oneta, Carl, Oropesa, Cassandra, Peter, Ueli, Peternac, Daniel, Marie Petit, Laetitia, Piccoli-Gfeller, Franziska, Beatrice Pilz, Julia, Pittet, Valérie, Raschle, Nadia, Rentsch, Ronald, Restellini, Sophie, Richterich, Jean-Pierre, Rihs, Sylvia, Alain Ritz, Marc, Roduit, Jocelyn, Rogler, Daniela, Rogler, Gerhard, Rossel, Jean-Benoît, Sagmeister, Markus, Saner, Gaby, Sauter, Bernhard, Sawatzki, Mikael, Schäppi, Michela, Scharl, Michael, Schelling, Martin, Schibli, Susanne, Schlauri, Hugo, Schmid Uebelhart, Sybille, Schnegg, Jean-François, Schoepfer, Alain, Seibold, Frank, Seirafi, Mariam, Semadeni, Gian-Marco, Semela, David, Senning, Arne, Sidler, Marc, Sokollik, Christiane, Spalinger, Johannes, Spangenberger, Holger, Stadler, Philippe, Steuerwald, Michael, Straumann, Alex, Straumann-Funk, Bigna, Sulz, Michael, Thorens, Joël, Tiedemann, Sarah, Tutuian, Radu, Vavricka, Stephan, Viani, Francesco, Vögtlin, Jürg, Von Känel, Roland, Vonlaufen, Alain, Vouillamoz, Dominique, Vulliamy, Rachel, Wermuth, Jürg, Werner, Helene, Wiesel, Paul, Wiest, Reiner, Wylie, Tina, Zeitz, Jonas, Zimmermann, Dorothee, Mikocka-Walus, Antonina, Pittet, Valerie, and von Känel, Roland
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- 2016
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6. The Relevance of Vitamin and Iron Deficiency in Patients with Inflammatory Bowel Diseases in Patients of the Swiss IBD Cohort
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Madanchi, Matiar, Fagagnini, Stefania, Fournier, Nicolas, Biedermann, Luc, Zeitz, Jonas, Battegay, Edouard, Zimmerli, Lukas, Vavricka, Stephan R, Rogler, Gerhard, Scharl, Michael, Anderegg, Claudia, Bauerfeind, Peter, Beglinger, Christoph, Begré, Stefan, Belli, Dominique, Bengoa, José M, Biedermann, Luc, Bigler, Beat, Binek, Janek, Blattmann, Mirjam, Boehm, Stephan, Borovicka, Jan, Braegger, Christian P, Brunner, Nora, Bühr, Patrick, Burnand, Bernard, Burri, Emanuel, Buyse, Sophie, Cremer, Matthias, Criblez, Dominique H, Saussure, Philippe de, Degen, Lukas, Delarive, Joakim, Doerig, Christopher, Dora, Barbara, Dorta, Gian, Egger, Mara, Ehmann, Tobias, El-Wafa, Ali, Engelmann, Matthias, Ezri, Jessica, Felley, Christian, Fliegner, Markus, Fournier, Nicolas, Fraga, Montserrat, Frei, Pascal, Frei, Remus, Fried, Michael, Froehlich, Florian, Funk, Christian, Furlano, Raoul Ivano, Gallot-Lavallée, Suzanne, Geyer, Martin, Girardin, Marc, Golay, Delphine, Grandinetti, Tanja, Gysi, Beat, Haack, Horst, Haarer, Johannes, Helbling, Beat, Hengstler, Peter, Herzog, Denise, Hess, Cyrill, Heyland, Klaas, Hinterleitner, Thomas, Hiroz, Philippe, Hirschi, Claudia, Hruz, Petr, Iwata, Rika, Jost, Res, Juillerat, Pascal, Brondolo, Vera Kessler, Knellwolf, Christina, Knoblauch, Christoph, Köhler, Henrik, Koller, Rebekka, Krieger-Grübel, Claudia, Kullak-Ublick, Gerd, Künzler, Patrizia, Landolt, Markus, Lange, Rupprecht, Lehmann, Frank Serge, Macpherson, Andrew, Maerten, Philippe, Maillard, Michel H, Manser, Christine, Manz, Michael, Marbet, Urs, Marx, George, Matter, Christoph, McLin, Valérie, Meier, Rémy, Mendanova, Martina, Meyenberger, Christa, Michetti, Pierre, Misselwitz, Benjamin, Moradpour, Darius, Morell, Bernhard, Mosler, Patrick, Mottet, Christian, Müller, Christoph, Müller, Pascal, Müllhaupt, Beat, Münger-Beyeler, Claudia, Musso, Leilla, Nagy, Andreas, Neagu, Michaela, Nichita, Cristina, Niess, Jan, Noël, Natacha, Nydegger, Andreas, Obialo, Nicole, Oneta, Carl, Oropesa, Cassandra, Peter, Ueli, Peternac, Daniel, Petit, Laetitia Marie, Piccoli-Gfeller, Franziska, Pilz, Julia Beatrice, Pittet, Valérie, Raschle, Nadia, Rentsch, Ronald, Restellini, Sophie, Richterich, Jean-Pierre, Rihs, Sylvia, Ritz, Marc Alain, Roduit, Jocelyn, Rogler, Daniela, Rogler, Gerhard, Rossel, Jean-Benoît, Sagmeister, Markus, Saner, Gaby, Sauter, Bernhard, Sawatzki, Mikael, Schäppi, Michela, Scharl, Michael, Schelling, Martin, Schibli, Susanne, Schlauri, Hugo, Uebelhart, Sybille Schmid, Schnegg, Jean-François, Schoepfer, Alain, Seibold, Frank, Seirafi, Mariam, Semadeni, Gian-Marco, Semela, David, Senning, Arne, Sidler, Marc, Sokollik, Christiane, Spalinger, Johannes, Spangenberger, Holger, Stadler, Philippe, Steuerwald, Michael, Straumann, Alex, Straumann-Funk, Bigna, Sulz, Michael, Thorens, Joël, Tiedemann, Sarah, Tutuian, Radu, Vavricka, Stephan, Viani, Francesco, Vögtlin, Jürg, Känel, Roland Von, Vonlaufen, Alain, Vouillamoz, Dominique, Vulliamy, Rachel, Wermuth, Jürg, Werner, Helene, Wiesel, Paul, Wiest, Reiner, Wylie, Tina, Zeitz, Jonas, and Zimmermann, Dorothee
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- 2018
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7. Genetic polymorphisms associated with smoking behaviour predict the risk of surgery in patients with Crohnʼs disease
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Lang, B. M., Biedermann, L., van Haaften, W. T., de Vallière, C., Schuurmans, M., Begré, S., Zeitz, J., Scharl, M., Turina, M., Greuter, T., Schreiner, P., Heinrich, H., Kuntzen, T., Vavricka, S. R., Rogler, G., Beerenwinkel, N., Misselwitz, B., Anderegg, Claudia, Bauerfeind, Peter, Beglinger, Christoph, Begré, Stefan, Bengoa, José M., Biedermann, Luc, Bigler, Beat, Binek, Janek, Blattmann, Mirjam, Boehm, Stephan, Borovicka, Jan, Braegger, Christian P., Brunner, Nora, Bühr, Patrick, Burnand, Bernard, Burri, Emanuel, Buyse, Sophie, Cremer, Matthias, Criblez, Dominique H., de Saussure, Philippe, Degen, Lukas, Delarive, Joakim, Doerig, Christopher, Dora, Barbara, Dorta, Gian, Egger, Mara, Ehmann, Tobias, El‐Wafa, Ali, Engelmann, Matthias, Ezri, a, Felley, Christian, Fliegner, Markus, Fournier, Nicolas, Fraga, Montserrat, Frei, Pascal, Frei, Remus, Fried, Michael, Froehlich, Florian, Funk, Christian, Furlano, Raoul Ivano, Gallot‐Lavallée, Suzanne, Geyer, Martin, Girardin, Marc, Golay, Delphine, Grandinetti, Tanja, Gysi, Beat, Haack, Horst, Haarer, Johannes, Helbling, Beat, Hengstler, Peter, Herzog, Denise, Hess, Cyrill, Heyland, Klaas, Hinterleitner, Thomas, Hiroz, Philippe, Hirschi, Claudia, Hruz, Petr, Iwata, Rika, Jost, Res, Juillerat, Pascal, Kessler Brondolo, Vera, Knellwolf, Christina, Knoblauch, Christoph, Köhler, Henrik, Koller, Rebekka, Krieger‐Grübel, Claudia, Kullak‐Ublick, Gerd, Künzler, Patrizia, Landolt, Markus, Lange, Rupprecht, Lehmann, Frank Serge, Macpherson, Andrew, Maerten, Philippe, Maillard, Michel H., Manser, Christine, Manz, Michael, Marbet, Urs, Marx, George, Matter, Christoph, McLin, Valérie, Meier, Rémy, Mendanova, Martina, Meyenberger, Christa, Michetti, Pierre, Misselwitz, Benjamin, Moradpour, Darius, Morell, Bernhard, Mosler, Patrick, Mottet, Christian, Müller, Christoph, Müller, Pascal, Müllhaupt, Beat, Münger‐Beyeler, Claudia, Musso, Leilla, Nagy, Andreas, Neagu, Michaela, Nichita, Cristina, Niess, Jan, Noël, Natacha, Nydegger, Andreas, Obialo, Nicole, Oneta, Carl, Oropesa, Cassandra, Peter, Ueli, Peternac, Daniel, Petit, Laetitia Marie, Piccoli‐Gfeller, Franziska, Pilz, Julia Beatrice, Pittet, Valérie, Raschle, Nadia, Rentsch, Ronald, Restellini, Sophie, Richterich, Jean‐Pierre, Rihs, Sylvia, Ritz, Marc Alain, Roduit, Jocelyn, Rogler, Daniela, Rogler, Gerhard, Rossel, Jean‐Benoît, Sagmeister, Markus, Saner, Gaby, Sauter, Bernhard, Sawatzki, Mikael, Schäppi, Michela, Scharl, Michael, Schelling, Martin, Schibli, Susanne, Schlauri, Hugo, Uebelhart, Sybille Schmid, Schnegg, Jean‐François, Schoepfer, Alain, Seibold, Frank, Seirafi, Mariam, Semadeni, Gian‐Marco, Semela, David, Senning, Arne, Sidler, Marc, Sokollik, Christiane, Spalinger, Johannes, Spangenberger, Holger, Stadler, Philippe, Steuerwald, Michael, Straumann, Alex, Straumann‐Funk, Bigna, Sulz, Michael, Thorens, Joël, Tiedemann, Sarah, Tutuian, Radu, Vavricka, Stephan, Viani, Francesco, Vögtlin, Jürg, Von Känel, Roland, Vonlaufen, Alain, Vouillamoz, Dominique, Vulliamy, Rachel, Wermuth, Jürg, Werner, Helene, Wiesel, Paul, Wiest, Reiner, Wylie, Tina, Zeitz, Jonas, and Zimmermann, Dorothee
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- 2018
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8. Video Capsule Endoscopy in Pediatric Inflammatory Bowel Disease
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Girardin, Marc, Seidman, Ernest G., Mamula, Petar, editor, Markowitz, Jonathan E., editor, and Baldassano, Robert N., editor
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- 2008
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9. Expression and functional analysis of intestinal organic cation/l-carnitine transporter (OCTN) in Crohn's Disease
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Girardin, Marc, Dionne, Serge, Goyette, Philippe, Rioux, John, Bitton, Alain, Elimrani, Ihsan, Charlebois, Patrick, Qureshi, Ijaz, Levy, Emile, and Seidman, Ernest G.
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- 2012
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10. Impact of the early use of immunomodulators or TNF antagonists on bowel damage and surgery in Crohnʼs disease
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Safroneeva, E., Vavricka, S. R., Fournier, N., Pittet, V., Peyrin-Biroulet, L., Straumann, A., Rogler, G., Schoepfer, A. M., Bauerfeind, Peter, Beglinger, Christoph, Begré, Stefan, Bengoa, José, Binek, Janek, Boller, Daniel, Borovicka, Jan, Braegger, Christian, Burnand, Bernard, Camara, Rafael, Criblez, Dominique, de Saussure, Philippe, Degen, Lukas, Delarive, Joakim, Ehmann, Tobias, Engelmann, Matthias, Wafa, Ali El, Felley, Christian, Frei, Alain, Frei, Remus, Fried, Michael, Friedt, Michael, Froehlich, Florian, Gallot-Lavallée, Suzanne, Gerlach, Tilman, Geyer, Martin, Girardin, Marc, Goetze, Oliver, Haack, Horst, Hediger, Serge, Hengstler, Peter, Heyland, Klaas, Janiak, Patrick, Juillerat, Pascal, Brondolo, Vera Kessler, Knoblauch, Christoph, Kullak-Ublick, Gerd A., Maillard, Michel, Manz, Michael, Marbet, Urs, Meier, Rémy, Meyenberger, Christa, Michetti, Pierre, Mottet, Christian, Müller, Christoph, Müllhaupt, Beat, Nicolet, Thierry, Nydegger, Andreas, Pache, Isabelle, Piccoli, Franziska, Pilz, Julia, Rentsch, Ronald, Rey, Jean-Pierre, Rihs, Silvia, Rogler, Daniela, Sagmeister, Markus, Sauter, Bernhard, Schaub, Niklaus, Schibli, Susanne, Seibold, Frank, Spalinger, Johannes, Stadler, Philippe, Steuerwald, Michael, Sul, Michael, Tempia-Caliera, Michela, Thorens, Joël, Vader, John-Paul, Vögtlin, Jürg, Von Känel, Roland, Wachter, Gert, Wermuth, Jürg, and Wiesel, Paul
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- 2015
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11. Systematic analysis of factors associated with progression and regression of ulcerative colitis in 918 patients
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Safroneeva, E., Vavricka, S., Fournier, N., Seibold, F., Mottet, C., Nydegger, A., Ezri, J., Straumann, A., Rogler, G., Schoepfer, A. M., Bauerfeind, Peter, Beglinger, Christoph, Begré, Stefan, Bengoa, José, Binek, Janek, Boller, Daniel, Borovicka, Jan, Braegger, Christian, Burnand, Bernard, Camara, Rafael, Criblez, Dominique, de Saussure, Philippe, Degen, Lukas, Delarive, Joakim, Ehmann, Tobias, Engelmann, Matthias, Wafa, Ali El, Felley, Christian, Frei, Alain, Frei, Pascal, Frei, Remus, Fried, Michael, Froehlich, Florian, Gallot-Lavallée, Suzanne, Gerlach, Tilman, Geyer, Martin, Girardin, Marc, Goetze, Oliver, Haack, Horst, Hediger, Serge, Hengstler, Peter, Heyland, Klaas, Janiak, Patrick, Juillerat, Pascal, Brondolo, Vera Kessler, Knoblauch, Christoph, Kullak-Ublick, Gerd A., Maillard, Michel, Manser, Christine, Marbet, Urs, Manz, Michael, Meier, Rémy, Meyenberger, Christa, Michetti, Pierre, Mottet, Christian, Müller, Christoph, Müllhaupt, Beat, Nicolet, Thierry, Nydegger, Andreas, Piccoli, Franziska, Pilz, Julia, Pittet, Valérie, Rentsch, Ronald, Rey, Jean-Pierre, Rogler, Daniela, Rogler, Gerhard, Sagmeister, Markus, Sauter, Bernhard, Schaub, Niklaus, Schibli, Susanne, Schoepfer, Alain M., Seibold, Frank, Spalinger, Johannes, Stadler, Philippe, Steuerwald, Michael, Straumann, Alex, Sulz, Michael, Thorens, Joël, Vader, John-Paul, Vavricka, Stephan R., Vögtlin, Jürg, Von Känel, Roland, Wachter, Gert, Wermuth, Jürg, and Wiesel, Paul
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- 2015
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12. Symptoms of Depression and Anxiety Are Independently Associated With Clinical Recurrence of Inflammatory Bowel Disease
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Mikocka-Walus, Antonina, Pittet, Valerie, Rossel, Jean-Benoît, von Känel, Roland, Anderegg, Claudia, Bauerfeind, Peter, Beglinger, Christoph, Begré, Stefan, Belli, Dominique, Bengoa, José M., Biedermann, Luc, Bigler, Beat, Binek, Janek, Blattmann, Mirjam, Boehm, Stephan, Borovicka, Jan, Braegger, Christian P., Brunner, Nora, Bühr, Patrick, Burnand, Bernard, Burri, Emanuel, Buyse, Sophie, Cremer, Matthias, Criblez, Dominique H., de Saussure, Philippe, Degen, Lukas, Delarive, Joakim, Doerig, Christopher, Dora, Barbara, Dorta, Gian, Egger, Mara, Ehmann, Tobias, El-Wafa, Ali, Engelmann, Matthias, Ezri, Jessica, Felley, Christian, Fliegner, Markus, Fournier, Nicolas, Fraga, Montserrat, Frei, Pascal, Frei, Remus, Fried, Michael, Froehlich, Florian, Funk, Christian, Ivano Furlano, Raoul, Gallot-Lavallée, Suzanne, Geyer, Martin, Girardin, Marc, Golay, Delphine, Grandinetti, Tanja, Gysi, Beat, Haack, Horst, Haarer, Johannes, Helbling, Beat, Hengstler, Peter, Herzog, Denise, Hess, Cyrill, Heyland, Klaas, Hinterleitner, Thomas, Hiroz, Philippe, Hirschi, Claudia, Hruz, Petr, Iwata, Rika, Jost, Res, Juillerat, Pascal, Kessler Brondolo, Vera, Knellwolf, Christina, Knoblauch, Christoph, Köhler, Henrik, Koller, Rebekka, Krieger-Grübel, Claudia, Kullak-Ublick, Gerd, Künzler, Patrizia, Landolt, Markus, Lange, Rupprecht, Serge Lehmann, Frank, Macpherson, Andrew, Maerten, Philippe, Maillard, Michel H., Manser, Christine, Manz, Michael, Marbet, Urs, Marx, George, Matter, Christoph, McLin, Valérie, Meier, Rémy, Mendanova, Martina, Meyenberger, Christa, Michetti, Pierre, Misselwitz, Benjamin, Moradpour, Darius, Morell, Bernhard, Mosler, Patrick, Mottet, Christian, Müller, Christoph, Müller, Pascal, Müllhaupt, Beat, Münger-Beyeler, Claudia, Musso, Leilla, Nagy, Andreas, Neagu, Michaela, Nichita, Cristina, Niess, Jan, Noël, Natacha, Nydegger, Andreas, Obialo, Nicole, Oneta, Carl, Oropesa, Cassandra, Peter, Ueli, Peternac, Daniel, Marie Petit, Laetitia, Piccoli-Gfeller, Franziska, Beatrice Pilz, Julia, Pittet, Valérie, Raschle, Nadia, Rentsch, Ronald, Restellini, Sophie, Richterich, Jean-Pierre, Rihs, Sylvia, Alain Ritz, Marc, Roduit, Jocelyn, Rogler, Daniela, Rogler, Gerhard, Rossel, Jean-Benoît, Sagmeister, Markus, Saner, Gaby, Sauter, Bernhard, Sawatzki, Mikael, Schäppi, Michela, Scharl, Michael, Schelling, Martin, Schibli, Susanne, Schlauri, Hugo, Schmid Uebelhart, Sybille, Schnegg, Jean-François, Schoepfer, Alain, Seibold, Frank, Seirafi, Mariam, Semadeni, Gian-Marco, Semela, David, Senning, Arne, Sidler, Marc, Sokollik, Christiane, Spalinger, Johannes, Spangenberger, Holger, Stadler, Philippe, Steuerwald, Michael, Straumann, Alex, Straumann-Funk, Bigna, Sulz, Michael, Thorens, Joël, Tiedemann, Sarah, Tutuian, Radu, Vavricka, Stephan, Viani, Francesco, Vögtlin, Jürg, Von Känel, Roland, Vonlaufen, Alain, Vouillamoz, Dominique, Vulliamy, Rachel, Wermuth, Jürg, Werner, Helene, Wiesel, Paul, Wiest, Reiner, Wylie, Tina, Zeitz, Jonas, and Zimmermann, Dorothee
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- 2016
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13. Intolérances alimentaires et supervision de votre étudiant/interne : par où commencer ?
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Rieder, Arabelle Rachel, Junod Perron, Noëlle Astrid, Girardin, Marc, and Audetat Voirol, Marie-Claude
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ddc:610/370 ,ddc:613 - Published
- 2020
14. Effects of anti-TNF therapy and immunomodulators on anxiety and depressive symptoms in patients with inflammatory bowel disease: a 5-year analysis
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Siebenhüner, Alexander R., primary, Rossel, Jean-Benoît, additional, Schreiner, Philipp, additional, Butter, Matthias, additional, Greuter, Thomas, additional, Krupka, Niklas, additional, Jordi, Sebastian B. U., additional, Biedermann, Luc, additional, Rogler, Gerhard, additional, Misselwitz, Benjamin, additional, von Känel, Roland, additional, Abdelrahman, Karim, additional, Ademi, Gentiana, additional, Aepli, Patrick, additional, Thomas, Amman, additional, Anderegg, Claudia, additional, Antonino, Anca-Teodora, additional, Archanioti, Eva, additional, Arrigoni, Eviano, additional, Aslan, Nurullah, additional, Bakker de Jong, Diana, additional, Balsiger, Bruno, additional, Barry, Mamadou-Pathé, additional, Bastürk, Polat, additional, Bauerfeind, Peter, additional, Becocci, Andrea, additional, Bengoa, José M., additional, Binek, Janek, additional, Blattmann, Mirjam, additional, Boehm, Stephan, additional, Boldanova, Tujana, additional, Borovicka, Jan, additional, Braegger, Christian P., additional, Brand, Stephan, additional, Bravo, Francisco, additional, Brügger, Lukas, additional, Brunner, Simon, additional, Bühr, Patrick, additional, Burk, Sabine, additional, Burri, Emanuel, additional, Buyse, Sophie, additional, Cao, Dahlia-Thao, additional, Carstens, Ove, additional, Criblez, Dominique H., additional, D’Angelo, Fabrizia, additional, Saussure, Philippe de, additional, Degen, Lukas, additional, Delarive, Joakim, additional, Doerig, Christopher, additional, Dora, Barbara, additional, Drerup, Susan, additional, Ducrey, Carole, additional, El-Wafa, Ali, additional, Engelmann, Matthias, additional, Erdmann-Voisin, Aude, additional, Felley, Christian, additional, Fliegner, Markus, additional, Fraga, Montserrat, additional, Franc, Yannick, additional, Frei, Pascal, additional, Frei, Remus, additional, Fried, Michael, additional, Froehlich, Florian, additional, Ivano Furlano, Raoul, additional, Garzoni, Luca, additional, Geyer, Martin, additional, Girardin, Marc, additional, Golay, Delphine, additional, Good, Ignaz, additional, Graf Bigler, Ulrike, additional, Godat, Sébastien, additional, Gysi, Beat, additional, Haarer, Johannes, additional, Halama, Marcel, additional, Haldemann, Janine, additional, Heer, Pius, additional, Heimgartner, Benjamin, additional, Helbling, Beat, additional, Hengstler, Peter, additional, Herzog, Denise, additional, Hess, Cyrill, additional, Hessler, Roxane, additional, Heyland, Klaas, additional, Hinterleitner, Thomas, additional, Hirschi, Claudia, additional, Hruz, Petr, additional, Juillerat, Pascal, additional, Kapoglou, Ioannis, additional, Kayser, Stephan, additional, Keller, Céline, additional, Khalid-de Bakker, Carolina, additional, Knellwolf, Christina, additional, Knoblauch, Christoph, additional, Köhler, Henrik, additional, Koller, Rebekka, additional, Krieger, Claudia, additional, Künzler, Patrizia, additional, Kusche, Rachel, additional, Serge Lehmann, Frank, additional, Macpherson, Andrew, additional, Maillard, Michel H., additional, Manz, Michael, additional, Martinho, Maude, additional, Meier, Rémy, additional, Meyenberger, Christa, additional, Meyer, Pamela, additional, Michetti, Pierre, additional, Morell, Bernhard, additional, Mosler, Patrick, additional, Moschouri, Eleni, additional, Mottet, Christian, additional, Müller, Christoph, additional, Müllhaupt, Beat, additional, Musso, Leilla, additional, Neagu, Michaela, additional, Nichita, Cristina, additional, Niess, Jan, additional, Nydegger, Andreas, additional, Obialo, Nicole, additional, Oropesa, Cassandra, additional, Peter, Ulrich, additional, Peternac, Daniel, additional, Marie Petit, Laetitia, additional, Pittet, Valérie, additional, Pohl, Daniel, additional, Porzner, Marc, additional, Preissler, Claudia, additional, Raschle, Nadia, additional, Rentsch, Ronald, additional, Restellini, Sophie, additional, Richterich, Jean-Pierre, additional, Riedmüller, Sandra, additional, Risti, Branislav, additional, Alain Ritz, Marc, additional, Röhrich, Nina, additional, Roth, René, additional, Rueger, Vanessa, additional, Sagmeister, Markus, additional, Saner, Gaby, additional, Sarraj, Riad, additional, Sauter, Bernhard, additional, Sawatzki, Mikael, additional, Scharl, Michael, additional, Scharl, Sylvie, additional, Schelling, Martin, additional, Schibli, Susanne, additional, Schlauri, Hugo, additional, Schluckebier, Dominique, additional, Schmid, Daniela, additional, Schmid, Sybille, additional, Schnegg, Jean-François, additional, Schoepfer, Alain, additional, Seibold, Frank, additional, Seirafi, Mariam, additional, Semadeni, Gian-Marco, additional, Senning, Arne, additional, Sokollik, Christiane, additional, Sommer, Joachim, additional, Spalinger, Johannes, additional, Spangenberger, Holger, additional, Stadler, Philippe, additional, Staub, Peter, additional, Staudenmann, Dominic, additional, Stenz, Volker, additional, Steuerwald, Michael, additional, Straumann, Alex, additional, Stulz, Andreas, additional, Sulz, Michael, additional, Tempia-Caliera, Michela, additional, Thorens, Joël, additional, Truninger, Kaspar, additional, Tutuian, Radu, additional, Urfer, Patrick, additional, Vavricka, Stephan, additional, Viani, Francesco, additional, Vinzens, Fabrizion, additional, Vögtlin, Jürg, additional, Von Känel, Roland, additional, Vouillamoz, Dominique, additional, Vulliamy, Rachel, additional, Vullièmoz, Marianne, additional, Wiesel, Paul, additional, Wiest, Reiner, additional, Wöhrle, Stefanie, additional, Yilmaz, Bahtiyar, additional, Zamora, Samuel, additional, Zander, Silvan, additional, Zeitz, Jonas, additional, and Zimmermann, Dorothee, additional
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- 2021
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15. Cryptococcal Gastroduodenitis: A Rare Location of the Disease
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Girardin, Marc, Greloz, Vincent, and Hadengue, Antoine
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- 2010
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16. High Immunogenicity of the Pneumococcal Conjugated Vaccine in Immunocompromised Adults With Inflammatory Bowel Disease
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Pittet, Laure, Verolet, Charlotte, Michetti, Pierre, Girardin, Marc, Juillerat, Pascal, Mottet, Christian, Maillard, Michel H, Siegrist, Claire-Anne, Posfay Barbe, Klara, and Swiss Inflammatory Bowel Disease Cohort Study Group
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Male ,medicine.medical_treatment ,Pneumococcal Vaccines/administration & dosage/immunology ,Immunomodulation/immunology ,Inflammatory bowel disease ,Pneumococcal Vaccines ,0302 clinical medicine ,Vaccines, Conjugate/administration & dosage/immunology ,610 Medicine & health ,ddc:616 ,ddc:618 ,Immunogenicity ,Vaccination ,Gastroenterology ,Inflammatory Bowel Diseases/drug therapy/immunology ,Immunosuppression ,Middle Aged ,Pneumococcal infections ,Treatment Outcome ,Underlying disease ,030220 oncology & carcinogenesis ,030211 gastroenterology & hepatology ,Female ,Patient Safety ,Immunosuppressive Agents ,Switzerland ,Adult ,Risk Assessment ,Pneumococcal Infections ,Immunomodulation ,03 medical and health sciences ,Immunocompromised Host ,medicine ,Humans ,Vaccination/methods ,Pneumococcal Infections/prevention & control ,Analysis of Variance ,Vaccines, Conjugate ,Hepatology ,business.industry ,medicine.disease ,Inflammatory Bowel Diseases ,digestive system diseases ,Clinical trial ,Multicenter study ,Immunology ,Linear Models ,Immunosuppressive Agents/therapeutic use ,business - Abstract
INTRODUCTION Patients with inflammatory bowel disease (IBD) are predisposed to pneumococcal infections due to their underlying disease and iatrogenic immunosuppression. Vaccination with the 13-valent pneumococcal conjugated vaccine (PCV13) is recommended, but with poor take-up and few data available. We performed an open-label, phase IV, multicenter study to evaluate the safety and immunogenicity of PCV13 in adults with IBD and to analyze the influence of immunomodulating treatments on anti-pneumococcal seroresponses. METHODS We enrolled 306 patients with IBD from March 2014 through February 2016, with the following exclusion criteria: current IBD flare, pregnancy, pneumococcal immunization in the previous 5 years, and influenza immunization in the previous 4 weeks. PCV13 was administered intramuscularly. Serotype-specific vaccine responses were evaluated using an opsonophagocytic assay. Adverse events were monitored by diary cards and standardized phone interviews. RESULTS The median seroprotection rate increased significantly from 43.9% (95% confidence interval [CI], 42.3-45.5) at inclusion to 90.4% (95% CI, 89.5-91.3%; P < 0.001) after vaccination. Patients receiving anti-tumor necrosis factor agents achieved a slightly lower seroprotection rate (from 44.5% [95% CI, 42.3%-46.8%] to 86.6% [95% CI, 84.9%-88.1%]) than patients treated with other types of immunosuppressive regimens (thiopurine, methotrexate, oral corticosteroids; from 44.7% [95% CI, 41.7%-47.7%] to 93.8% [95% CI, 92.1%-95.2%]) or nonimmunosuppressive treatment (5-aminosalicylate, topical corticosteroids, vedolizumab; from 41.3% [95% CI, 37.9%-44.8%] to 95.2% [95% CI, 93.4%-96.6%]). There were no safety issues. DISCUSSION Overall, the administration of PCV13 was highly immunogenic and well tolerated, irrespective of the baseline treatment, and should be encouraged in all adults with IBD.
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- 2019
17. A case of acute loss of vision as the presenting symptom of Crohn's disease
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Girardin, Marc, Waschke, Kevin A, and Seidman, Ernest G
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- 2007
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18. Risk of Vaccine-Preventable Infections in Swiss Adults with Inflammatory Bowel Disease.
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Pittet, Laure F., Verolet, Charlotte M., Michetti, Pierre, Gaillard, Elsa, Girardin, Marc, Juillerat, Pascal, Mottet, Christian, Maillard, Michel H., Siegrist, Claire-Anne, and Posfay-Barbe, Klara M.
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INFLAMMATORY bowel diseases ,CROHN'S disease ,BOOSTER vaccines ,PREVENTIVE medicine ,TICK-borne encephalitis - Abstract
Background: Patients with inflammatory bowel disease (IBD) have a higher risk of infection and are frequently not up to date with their immunizations. Objectives: This study aims to review vaccination status and evaluate whether age, disease type, or treatment regimen could predict the absence of seroprotection against selected vaccine-preventable infection in adults with IBD. Methods: Cross-sectional study using questionnaire, immunization records review, and assessment of tetanus-specific, varicella-specific, and measles-specific immunoglobulin G concentrations. ClinicalTrials.gov: NCT01908283. Results: Among the 306 adults assessed (median age 42.7 years old, 70% with Crohn's disease, 78% receiving immunosuppressive treatment), only 33% had an immunization record available. Absence of seroprotection against tetanus (6%) was associated with increasing age and absence of booster dose; absence of seroprotection against varicella (1%) or measles (3%) was exclusively observed in younger patients with Crohn's disease. There was no statistically significant difference in immunoglobulin concentrations among treatment groups. Although vaccinations are strongly recommended in IBD patients, the frequencies of participants with at least 1 dose of vaccine recorded were low for nearly all antigens: tetanus 94%, diphtheria 87%, pertussis 54%, poliovirus 22%, measles-mumps-rubella 47%, varicella-zoster 0%, Streptococcus pneumoniae 5%, Neisseria meningitidis 12%, hepatitis A 41%, hepatitis B 48%, human papillomavirus 5%, and tick-borne encephalitis 6%. Conclusions: Although many guidelines recommend the vaccination of IBD patients, disease prevention through immunization is still often overlooked, including in Switzerland, increasing their risk of vaccine-preventable diseases. Serological testing should be standardized to monitor patients' protection during follow-up as immunity may wane faster in this population. [ABSTRACT FROM AUTHOR]
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- 2021
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19. Cohort Profile: The Swiss Eosinophilic Esophagitis Cohort Study (SEECS)
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Safroneeva, Ekaterina, Saner, Catherine, Rossel, Jean-Benoît, Golay, Delphine, Pittet, Valérie, Godat, Sébastien, Diem, Stefan, Aepli, Patrick, Sawatzki, Mikael, Borovicka, Jan, Burgmann, Konstantin, Juillerat, Pascal, Netzer, Peter, Sendensky, Alexander, Hruz, Petr, Girardin, Marc, Biedermann, Luc, Greuter, Thomas, Vavricka, Stephan, Michetti, Pierre, Mueller, Christoph, Straumann, Alex, Schoepfer, Alain M, Swiss EoE Cohort Study Group, and University of Zurich
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10219 Clinic for Gastroenterology and Hepatology ,570 Life sciences ,biology ,610 Medicine & health ,360 Social problems & social services - Abstract
Background and Aims The prospective, observational Swiss Eosinophilic Esophagitis Cohort Study (SEECS) was set up in 2015 with the following goals in mind: (1) to provide up-to-date epidemiologic data; (2) to assess the appropriateness of care; (3) to evaluate the psychosocial impact; and (4) to foster translational research projects. Data capture relies on validated instruments to assess disease activity and focuses on epidemiologic variables and biosamples (esophageal biopsies and blood specimens). An annual inclusion of 70 new patients with eosinophilic esophagitis (EoE) or proton pump inhibitor-responsive esophageal eosinophilia (PPI-REE) is intended. We herein describe the SEECS cohort profile. Methods The SEECS includes adult patients (age ≥18 years) with EoE or PPI-REE diagnosed according to published criteria. After inclusion, the patients are typically seen once a year for a clinical and endoscopic/histologic follow-up examination. Data are captured using validated questionnaires. Biosamples from patients with gastroesophageal reflux disease (GERD) and controls with a healthy esophagus are collected as well. Results From January 2016 to July 2017, a total of 111 patients with EoE and 10 patients with PPI-REE were recruited. In addition, esophageal biopsies and blood samples from 11 patients with GERD and 20 controls with a healthy esophagus were collected. The mean age of the patients with EoE and those with PPI-REE was 39.6 ± 12.9 and 44.6 ± 15.6 years, respectively. A male predominance was found among both the patients with EoE (77.5%) and those with PPI-REE (70%). Concomitant allergic disorders were found in 79.3% of the patients with EoE and 90% of the patients with PPI-REE. At inclusion, the EoE patients were treated with the following therapeutic regimens: no therapy (0.9%), PPI (36%), swallowed topical corticosteroids (82.9%), elimination diets (15.3%), and esophageal dilation (19.8%). Conclusions The SEECS is the first national cohort study of patients with EoE or PPI-REE. The SEECS will provide up-to-date epidemiologic data and foster translational research projects.
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- 2018
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20. Differences in Outcomes Reported by Patients With Inflammatory Bowel Diseases vs Their Health Care Professionals
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Pittet, Valérie E.H., primary, Maillard, Michel H., additional, Simonson, Thomas, additional, Fournier, Nicolas, additional, Rogler, Gerhard, additional, Michetti, Pierre, additional, Anderegg, Claudia, additional, Bauerfeind, Peter, additional, Beglinger, Christoph, additional, Begré, Stefan, additional, Belli, Dominique, additional, Bengoa, José M., additional, Biedermann, Luc, additional, Bigler, Beat, additional, Binek, Janek, additional, Blattmann, Mirjam, additional, Boehm, Stephan, additional, Borovicka, Jan, additional, Braegger, Christian P., additional, Brunner, Nora, additional, Bühr, Patrick, additional, Burnand, Bernard, additional, Burri, Emanuel, additional, Buyse, Sophie, additional, Cremer, Matthias, additional, Criblez, Dominique H., additional, de Saussure, Philippe, additional, Degen, Lukas, additional, Delarive, Joakim, additional, Doerig, Christopher, additional, Dora, Barbara, additional, Dorta, Gian, additional, Egger, Mara, additional, Ehmann, Tobias, additional, El-Wafa, Ali, additional, Engelmann, Matthias, additional, Ezri, Jessica, additional, Felley, Christian, additional, Fliegner, Markus, additional, Fraga, Montserrat, additional, Frei, Pascal, additional, Frei, Remus, additional, Fried, Michael, additional, Froehlich, Florian, additional, Funk, Christian, additional, Furlano, Raoul Ivano, additional, Gallot-Lavallée, Suzanne, additional, Geyer, Martin, additional, Girardin, Marc, additional, Golay, Delphine, additional, Grandinetti, Tanja, additional, Gysi, Beat, additional, Haack, Horst, additional, Haarer, Johannes, additional, Helbling, Beat, additional, Hengstler, Peter, additional, Herzog, Denise, additional, Hess, Cyrill, additional, Heyland, Klaas, additional, Hinterleitner, Thomas, additional, Hiroz, Philippe, additional, Hirschi, Claudia, additional, Hruz, Petr, additional, Iwata, Rika, additional, Jost, Res, additional, Juillerat, Pascal, additional, Keller, Céline, additional, Knellwolf, Christina, additional, Knoblauch, Christoph, additional, Köhler, Henrik, additional, Koller, Rebekka, additional, Krieger-Grübel, Claudia, additional, Kullak-Ublick, Gerd, additional, Künzler, Patrizia, additional, Landolt, Markus, additional, Lange, Rupprecht, additional, Lehmann, Frank Serge, additional, Macpherson, Andrew, additional, Maerten, Philippe, additional, Manser, Christine, additional, Manz, Michael, additional, Marbet, Urs, additional, Marx, George, additional, Matter, Christoph, additional, Meier, Rémy, additional, Mendanova, Martina, additional, Misselwitz, Benjamin, additional, Morell, Bernhard, additional, Mosler, Patrick, additional, Mottet, Christian, additional, Müller, Christoph, additional, Müller, Pascal, additional, Müllhaupt, Beat, additional, Münger-Beyeler, Claudia, additional, Musso, Leilla, additional, Nagy, Andreas, additional, Neagu, Michaela, additional, Nichita, Cristina, additional, Niess, Jan, additional, Nydegger, Andreas, additional, Obialo, Nicole, additional, Oneta, Carl, additional, Oropesa, Cassandra, additional, Peter, Ueli, additional, Peternac, Daniel, additional, Petit, Laetitia Marie, additional, Piccoli-Gfeller, Franziska, additional, Pilz, Julia Beatrice, additional, Pittet, Valérie, additional, Raschle, Nadia, additional, Rentsch, Ronald, additional, Restellini, Sophie, additional, Richterich, Jean-Pierre, additional, Rihs, Sylvia, additional, Ritz, Marc Alain, additional, Roduit, Jocelyn, additional, Rogler, Daniela, additional, Rossel, Jean-Benoît, additional, Rueger, Vanessa, additional, Saner, Gaby, additional, Sauter, Bernhard, additional, Sawatzki, Mikael, additional, Schäppi, Michela, additional, Scharl, Michael, additional, Scharl, Sylvie, additional, Schelling, Martin, additional, Schibli, Susanne, additional, Schlauri, Hugo, additional, Uebelhart, Sybille Schmid, additional, Schnegg, Jean-François, additional, Schoepfer, Alain, additional, Seibold, Frank, additional, Seirafi, Mariam, additional, Semadeni, Gian-Marco, additional, Semela, David, additional, Senning, Arne, additional, Sidler, Marc, additional, Sokollik, Christiane, additional, Spalinger, Johannes, additional, Spangenberger, Holger, additional, Stadler, Philippe, additional, Steuerwald, Michael, additional, Straumann, Alex, additional, Straumann-Funk, Bigna, additional, Sulz, Michael, additional, Suter, Alexandra, additional, Thorens, Joël, additional, Tiedemann, Sarah, additional, Tutuian, Radu, additional, Vavricka, Stephan, additional, Viani, Francesco, additional, Vögtlin, Jürg, additional, Von Känel, Roland, additional, Vonlaufen, Alain, additional, Vouillamoz, Dominique, additional, Vulliamy, Rachel, additional, Wermuth, Jürg, additional, Werner, Helene, additional, Wiesel, Paul, additional, Wiest, Reiner, additional, Wylie, Tina, additional, Zeitz, Jonas, additional, and Zimmermann, Dorothee, additional
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- 2019
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21. 48 SMALL INTESTINAL MUCOSAL HEALING ASSESSED BY VIDEO CAPSULE ENDOSCOPY IN CROHN’S DISEASE PATIENTS TREATED WITH ADALIMUMAB: THE SIMCHA STUDY - INTERIM RESULTS
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Verdon, Christine, primary, Reinglas, Jason, additional, Kopylov, Uri, additional, Chao, Che-Yung, additional, Restellini, Sophie, additional, Girardin, Marc, additional, Afif, Waqqas, additional, Lakatos, Peter L., additional, Bessissow, Talat, additional, Bitton, Alain, additional, and Seidman, Ernest G., additional
- Published
- 2019
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22. Uveitis manifestations in patients of the Swiss Inflammatory Bowel Disease Cohort Study
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Biedermann, Luc, primary, Renz, Laura, additional, Fournier, Nicolas, additional, Rossel, Jean-Benoît, additional, Butter, Matthias, additional, Bluemel, Sena, additional, Vavricka, Stephan R., additional, Rogler, Gerhard, additional, Scharl, Michael, additional, Anderegg, Claudia, additional, Bauerfeind, Peter, additional, Beglinger, Christoph, additional, Begré, Stefan, additional, Belli, Dominique, additional, Bengoa, José M., additional, Biedermann, Luc, additional, Bigler, Beat, additional, Binek, Janek, additional, Blattmann, Mirjam, additional, Boehm, Stephan, additional, Borovicka, Jan, additional, Braegger, Christian P., additional, Brunner, Nora, additional, Bühr, Patrick, additional, Burnand, Bernard, additional, Burri, Emanuel, additional, Buyse, Sophie, additional, Cremer, Matthias, additional, Criblez, Dominique H., additional, Saussure, Philippe de, additional, Degen, Lukas, additional, Delarive, Joakim, additional, Doerig, Christopher, additional, Dora, Barbara, additional, Dorta, Gian, additional, Egger, Mara, additional, Ehmann, Tobias, additional, El-Wafa, Ali, additional, Engelmann, Matthias, additional, Ezri, Jessica, additional, Felley, Christian, additional, Fliegner, Markus, additional, Fraga, Montserrat, additional, Frei, Pascal, additional, Frei, Remus, additional, Fried, Michael, additional, Froehlich, Florian, additional, Funk, Christian, additional, Ivano Furlano, Raoul, additional, Gallot-Lavallée, Suzanne, additional, Geyer, Martin, additional, Girardin, Marc, additional, Golay, Delphine, additional, Grandinetti, Tanja, additional, Gysi, Beat, additional, Haack, Horst, additional, Haarer, Johannes, additional, Helbling, Beat, additional, Hengstler, Peter, additional, Herzog, Denise, additional, Hess, Cyrill, additional, Heyland, Klaas, additional, Hinterleitner, Thomas, additional, Hiroz, Philippe, additional, Hirschi, Claudia, additional, Hruz, Petr, additional, Iwata, Rika, additional, Jost, Res, additional, Juillerat, Pascal, additional, Kessler Brondolo, Vera, additional, Knellwolf, Christina, additional, Knoblauch, Christoph, additional, Köhler, Henrik, additional, Koller, Rebekka, additional, Krieger-Grübel, Claudia, additional, Kullak-Ublick, Gerd, additional, Künzler, Patrizia, additional, Landolt, Markus, additional, Lange, Rupprecht, additional, Serge Lehmann, Frank, additional, Macpherson, Andrew, additional, Maerten, Philippe, additional, Maillard, Michel H., additional, Manser, Christine, additional, Manz, Michael, additional, Marbet, Urs, additional, Marx, George, additional, Matter, Christoph, additional, McLin, Valérie, additional, Meier, Rémy, additional, Mendanova, Martina, additional, Meyenberger, Christa, additional, Michetti, Pierre, additional, Misselwitz, Benjamin, additional, Moradpour, Darius, additional, Morell, Bernhard, additional, Mosler, Patrick, additional, Mottet, Christian, additional, Müller, Christoph, additional, Müller, Pascal, additional, Müllhaupt, Beat, additional, Münger-Beyeler, Claudia, additional, Musso, Leilla, additional, Nagy, Andreas, additional, Neagu, Michaela, additional, Nichita, Cristina, additional, Niess, Jan, additional, Noël, Natacha, additional, Nydegger, Andreas, additional, Obialo, Nicole, additional, Oneta, Carl, additional, Oropesa, Cassandra, additional, Peter, Ueli, additional, Peternac, Daniel, additional, Marie Petit, Laetitia, additional, Piccoli-Gfeller, Franziska, additional, Beatrice Pilz, Julia, additional, Pittet, Valérie, additional, Raschle, Nadia, additional, Rentsch, Ronald, additional, Restellini, Sophie, additional, Richterich, Jean-Pierre, additional, Rihs, Sylvia, additional, Alain Ritz, Marc, additional, Roduit, Jocelyn, additional, Rogler, Daniela, additional, Sagmeister, Markus, additional, Saner, Gaby, additional, Sauter, Bernhard, additional, Sawatzki, Mikael, additional, Schäppi, Michela, additional, Schelling, Martin, additional, Schibli, Susanne, additional, Schlauri, Hugo, additional, Schmid Uebelhart, Sybille, additional, Schnegg, Jean-François, additional, Schoepfer, Alain, additional, Seibold, Frank, additional, Seirafi, Mariam, additional, Semadeni, Gian-Marco, additional, Semela, David, additional, Senning, Arne, additional, Sidler, Marc, additional, Sokollik, Christiane, additional, Spalinger, Johannes, additional, Spangenberger, Holger, additional, Stadler, Philippe, additional, Steuerwald, Michael, additional, Straumann, Alex, additional, Straumann-Funk, Bigna, additional, Sulz, Michael, additional, Thorens, Joël, additional, Tiedemann, Sarah, additional, Tutuian, Radu, additional, Vavricka, Stephan, additional, Viani, Francesco, additional, Vögtlin, Jürg, additional, Von Känel, Roland, additional, Vonlaufen, Alain, additional, Vouillamoz, Dominique, additional, Vulliamy, Rachel, additional, Wermuth, Jürg, additional, Werner, Helene, additional, Wiesel, Paul, additional, Wiest, Reiner, additional, Wylie, Tina, additional, Zeitz, Jonas, additional, and Zimmermann, Dorothee, additional
- Published
- 2019
- Full Text
- View/download PDF
23. High prevalence of cholestasis, with increased conjugated bile acids in inflammatory bowel diseases patients
- Author
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Girardin, Marc, primary and Hadengue, Antoine, additional
- Published
- 2018
- Full Text
- View/download PDF
24. Detection of Crohn Disease in Patients with Spondyloarthropathy: The SpACE Capsule Study
- Author
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Kopylov, Uri, primary, Starr, Michael, additional, Watts, Craig, additional, Dionne, Serge, additional, Girardin, Marc, additional, and Seidman, Ernest G., additional
- Published
- 2018
- Full Text
- View/download PDF
25. Information needs and concerns of patients with inflammatory bowel disease: what can we learn from participants in a bilingual clinical cohort?
- Author
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Pittet, Valérie, Vaucher, Carla, Maillard, Michel H, Girardin, Marc, de Saussure, Philippe, Burnand, Bernard, Rogler, Gerhard, Michetti, Pierre, Pittet, Valérie, Vaucher, Carla, Maillard, Michel H, Girardin, Marc, de Saussure, Philippe, Burnand, Bernard, Rogler, Gerhard, and Michetti, Pierre
- Abstract
BACKGROUND Inflammatory Bowel Disease (IBD) patients are confronted with needs and concerns related to their disease. AIM To explore information expectations of patients included in a national bilingual IBD cohort in Switzerland (SIBDC). METHODS This is a mixed-methods study, comprising 1) a semi-narrative survey sent to 1506 patients from the SIBDC and 2) two focus groups conducted with 14 patients to explore and assess the relevance of the survey's findings. Data collected within the framework of the SIBDC was used to characterize survey's responders. RESULTS 728 patients (48%) replied to the survey: 52.5% females, 56% Crohn's disease (CD), 87% secondary/tertiary level educated, 70% full/part-time employed. On average, 47% of patients sought for information, regardless of the disease stage; 27% of them were dissatisfied with information received at the time of first symptoms. During flares, 43% were concerned about drugs and therapies; in remission, 57% had concerns on research and developments; 27% searched for information linked to daily disease management. Information-seeking increased when active disease, for CD with high levels of perceived stress (OR = 2.47; p = 0.003), and for all with higher posttraumatic stress symptoms. The focus groups confirmed a perceived lack of information about general functioning, disease course, treatments and their risks, extra-intestinal symptoms and manifestations. CONCLUSIONS Information remains insufficient for IBD patients. Lack of information in specific domains can potentially cause stress and hinder detection of symptoms. Better information should be considered as a potentially important component in improving patients' outcomes in IBD.
- Published
- 2016
26. Tu1979 Capsule Endoscopy Reveals Small Intestinal Mucosal Crohn's Disease Healing After Treatment With Adalimumab: Preliminary Results of the SIMCHA Study
- Author
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Seidman, Ernest G., primary, Kopylov, Uri, additional, Chao, Che-Yung, additional, Girardin, Marc, additional, and Starr, Michael, additional
- Published
- 2016
- Full Text
- View/download PDF
27. Information Needs and Concerns of Patients with Inflammatory Bowel Disease: What Can We Learn from Participants in a Bilingual Clinical Cohort?
- Author
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Pittet, Valérie, primary, Vaucher, Carla, additional, Maillard, Michel H., additional, Girardin, Marc, additional, de Saussure, Philippe, additional, Burnand, Bernard, additional, Rogler, Gerhard, additional, and Michetti, Pierre, additional
- Published
- 2016
- Full Text
- View/download PDF
28. DOME/GALT type adenocarcimoma of the colon: a case report, literature review and a unified phenotypic categorization
- Author
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Kannuna, Hala, primary, Rubio, Carlos A., additional, Silverio, Patricia Caseiro, additional, Girardin, Marc, additional, Goossens, Nicolas, additional, Rubbia-Brandt, Laura, additional, and Puppa, Giacomo, additional
- Published
- 2015
- Full Text
- View/download PDF
29. Atteintes médicamenteuses du tractus gastro-intestinal: une revue clinico-pathologique
- Author
-
Pusztaszeri, Marc, Girardin, Marc, Hadengue, Antoine, Rubbia-Brandt, Laura, and Genevay-Infante, Muriel
- Subjects
ddc:616 ,Eosinophils ,Gastrointestinal Diseases/*chemically induced/*pathology ,Apoptosis/drug effects ,Gastrointestinal Tract/*drug effects/*pathology ,Colitis/chemically induced/pathology ,Humans ,Duodenal Ulcer/chemically induced/pathology ,ddc:616.07 ,Stomach Ulcer/chemically induced/pathology ,Severity of Illness Index ,Intestinal Mucosa/drug effects/pathology ,Esophagitis/chemically induced/pathology - Abstract
Many drugs are known to have adverse effects on the gastrointestinal tract. The consequences can range from asymptomatic histological lesions in the gastrointestinal mucosa to fatal complications such as haemorrhage or perforation. On the biopsies (or on surgical specimens), there is a limited number of injury pattern that should suggest drug-induced pathology. They are mostly non specific (ex: ulcer). However, some drugs may induce pathognomonic histological lesions. For this reason, the diagnosis of a drug-induced gastrointestinal pathology depends on a clinicopathological correlation and implies a good communication between the pathologist and the clinician. In this review, we focus on the most common and well-described drug-related clinico-pathological conditions of the gastrointestinal tract using an organ and lesion based approach.
- Published
- 2010
30. Monitoring disease activity and progression in Crohn's disease. A Swiss perspective on the IBD ahead 'optimised monitoring' recommendations
- Author
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Sauter, Bernhard, Beglinger, Christoph, Girardin, Marc, Macpherson, Andrew, Michetti, Pierre, Schoepfer, Alain, Seibold, Frank, Vavricka, Stephan R, Rogler, Gerhard, Sauter, Bernhard, Beglinger, Christoph, Girardin, Marc, Macpherson, Andrew, Michetti, Pierre, Schoepfer, Alain, Seibold, Frank, Vavricka, Stephan R, and Rogler, Gerhard
- Abstract
BACKGROUND AND AIMS: The structured IBD Ahead 'Optimised Monitoring' programme was designed to obtain the opinion, insight and advice of gastroenterologists on optimising the monitoring of Crohn's disease activity in four settings: (1) assessment at diagnosis, (2) monitoring in symptomatic patients, (3) monitoring in asymptomatic patients, and (4) the postoperative follow-up. For each of these settings, four monitoring methods were discussed: (a) symptom assessment, (b) endoscopy, (c) laboratory markers, and (d) imaging. Based on literature search and expert opinion compiled during an international consensus meeting, recommendations were given to answer the question 'which diagnostic method, when, and how often'. The International IBD Ahead Expert Panel advised to tailor this guidance to the healthcare system and the special prerequisites of each country. The IBD Ahead Swiss National Steering Committee proposes best-practice recommendations adapted for Switzerland. METHODS: The IBD Ahead Steering Committee identified key questions and provided the Swiss Expert Panel with a structured literature research. The expert panel agreed on a set of statements. During an international expert meeting the consolidated outcome of the national meetings was merged into final statements agreed by the participating International and National Steering Committee members - the IBD Ahead 'Optimized Monitoring' Consensus. RESULTS: A systematic assessment of symptoms, endoscopy findings, and laboratory markers with special emphasis on faecal calprotectin is deemed necessary even in symptom-free patients. The choice of recommended imaging methods is adapted to the specific situation in Switzerland and highlights the importance of ultrasonography and magnetic resonance imaging besides endoscopy. CONCLUSION: The recommendations stress the importance of monitoring disease activity on a regular basis and by objective parameters, such as faecal calprotectin and endoscopy with detailed documenta
- Published
- 2014
31. Use of glasgow-blatchford bleeding score reduces hospital stay duration and costs for patients with low-risk upper GI bleeding
- Author
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Girardin, Marc, additional, Bertolini, David, additional, Ditisheim, Saskia, additional, Frossard, Jean-Louis, additional, Giostra, Emiliano, additional, Goossens, Nicolas, additional, Morard, Isabelle, additional, Nguyen-Tang, Thai, additional, Spahr, Laurent, additional, Vonlaufen, Alain, additional, Hadengue, Antoine, additional, and Dumonceau, Jean-Marc, additional
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- 2014
- Full Text
- View/download PDF
32. Cancer pancréatique en 2014: épidémiologie et dépistage
- Author
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Bochatay, Laurent, primary, Girardin, Marc, additional, Bichard, Philippe, additional, and Frossard, Jean-Louis, additional
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- 2014
- Full Text
- View/download PDF
33. First-line therapies in inflammatory bowel disease
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Girardin, Marc, Manz, Michael, Manser, Christine, Biedermann, Luc, Wanner, Roger, Frei, Pascal, Safroneeva, Ekaterina, Mottet, Christian, Rogler, Gerhard, Schoepfer, Alain M, Girardin, Marc, Manz, Michael, Manser, Christine, Biedermann, Luc, Wanner, Roger, Frei, Pascal, Safroneeva, Ekaterina, Mottet, Christian, Rogler, Gerhard, and Schoepfer, Alain M
- Abstract
BACKGROUND AND AIMS: Medical therapy of inflammatory bowel disease (IBD) is becoming more complex, given the increasing choice of drugs to treat Crohn's disease (CD) and ulcerative colitis (UC). We aimed to summarize the current guidelines for first-line treatments in IBD. METHODS: An extensive literature search with focus on the guidelines of the European Crohn's and Colitis Organisation for the diagnosis and treatment of CD and UC was performed. First-line treatments were defined as the following drug categories: 5-aminosalicylates, budesonide, systemic steroids, azathioprine, 6-mercaptopurine, methotrexate, infliximab, adalimumab and certolizumab pegol. The following drug categories were not included: cyclosporine and tacrolimus (not yet approved by Swissmedic for IBD treatment). RESULTS: Treatment recommendations for the following clinically frequent situations are presented according to disease severity: ileocecal CD, colonic CD, proximal small bowel CD and perianal CD. For UC the following situations are presented: ulcerative proctitis, left-sided colitis and pancolitis. CONCLUSIONS: We provide a summary on the use of first-line therapies for clinically frequent situations in patients with CD and UC.
- Published
- 2012
34. First-Line Therapies in Inflammatory Bowel Disease
- Author
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Girardin, Marc, primary, Manz, Michael, additional, Manser, Christine, additional, Biedermann, Luc, additional, Wanner, Roger, additional, Frei, Pascal, additional, Safroneeva, Ekaterina, additional, Mottet, Christian, additional, Rogler, Gerhard, additional, and Schoepfer, Alain M., additional
- Published
- 2012
- Full Text
- View/download PDF
35. Place des [b]probiotiques[/b] dans le traitement des maladies inflammatoires intestinales
- Author
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Girardin, Marc, primary and Frossard, Jean-Louis, additional
- Published
- 2012
- Full Text
- View/download PDF
36. Primary Aortodigestive Fistula: A Rare and Potentially Lethal Cause of Gastrointestinal Hemorrhage
- Author
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Ditisheim, Saskia, primary, Girardin, Marc, additional, Dumonceau, Jean-Marc, additional, Hadengue, Antoine, additional, and Frossard, Jean Louis, additional
- Published
- 2011
- Full Text
- View/download PDF
37. Indications for the Use of Probiotics in Gastrointestinal Diseases
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Girardin, Marc, primary and Seidman, Ernest G., additional
- Published
- 2011
- Full Text
- View/download PDF
38. Detection of Small Bowel Inflammation Characteristic of Crohnʼs Disease in Spondyloarthropathy by Capsule Endoscopy Compared to Ileocolonoscopy: Preliminary Results of the Space Study
- Author
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Seidman, Ernest, primary, Costea, Florin, additional, Tamaz, Raja, additional, Girardin, Marc, additional, and Starr, Michael, additional
- Published
- 2010
- Full Text
- View/download PDF
39. M1823 Genetic and Functional Analysis of Intestinal Organic Cation/L-Carnitine Transporter (OCTN) in Crohn's Disease
- Author
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Girardin, Marc, primary, Goyette, Philippe, additional, Rioux, John D., additional, Dionne, Serge, additional, Charlebois, Patrick, additional, and Seidman, Ernest G., additional
- Published
- 2010
- Full Text
- View/download PDF
40. Inflammatory Bowel Disease in the Pediatric Population
- Author
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Girardin, Marc, primary and Seidman, Ernest G., additional
- Published
- 2010
- Full Text
- View/download PDF
41. Atteintes [b]médicamenteuses[/b] du tractus gastro-intestinal : une revue clinico-pathologique
- Author
-
Pusztaszeri, Marc, primary, Girardin, Marc, additional, Hadengue, Antoine, additional, Rubbia-Brandt, Laura, additional, and Genevay, Muriel, additional
- Published
- 2010
- Full Text
- View/download PDF
42. Quoi de [b]neuf[/b] pour le traitement de l’hépatite [b]B[/b] ?
- Author
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Negro, Francesco, primary, Bihl, Florian, additional, Alaei, Mahnaz, additional, and Girardin, Marc, additional
- Published
- 2009
- Full Text
- View/download PDF
43. M1190 Expression and Functional Analysis of Intestinal Organic Cation/L-Carnitine Transporter (OCTN) in Crohn's Disease
- Author
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Girardin, Marc, primary, Qureshi, Ijaz A., additional, Dionne, Serge, additional, Battat, Robert, additional, Bitton, Alain, additional, Charlebois, Patrick, additional, Wild, Gary E., additional, Waschke, Kevin A., additional, and Seidman, Ernest G., additional
- Published
- 2008
- Full Text
- View/download PDF
44. Video Capsule Endoscopy in Pediatric Inflammatory Bowel Disease.
- Author
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Mamula, Petar, Markowitz, Jonathan E., Baldassano, Robert N., Girardin, Marc, and Seidman, Ernest G.
- Published
- 2008
- Full Text
- View/download PDF
45. Experimental Study of Velocity Fields in a Human Nasal Fossa by Laser Anemometry
- Author
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Girardin, Marc, Bilgen, Ertugrul, and Arbour, Pierre
- Abstract
Velocity fields were mapped in a model of a human nasal fossa by laser doppler velocimetry, an innovative, quantitative and noninvasive method of optical anemometry, and by computerization. Other pertinent parameters were also calculated. Studies made at different cross sections of the nasal fossa showed the very definite influence not only of shapes and dimensions but also of direction of flow on velocity fields. The turbinates had a streamlining effect on the velocity fields while the liminal valve had a directional effect. Flow was usually greater in the lower half of the fossa and closer to the septum. The flow was generally turbulent. Velocity fields appear to give more information on intranasal aerodynamics than the calculated flow and Reynolds number for the sections studied, and this allows one to at least theorize that there may be an aerodynamic basis to certain pathological conditions of the nasal airway and its adjoining cavities, the paranasal sinuses, and the eustachian tubes.
- Published
- 1983
- Full Text
- View/download PDF
46. First-Line Therapies in Inflammatory Bowel Disease
- Author
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Michael Manz, Pascal Frei, Ekaterina Safroneeva, Christine N. Manser, Roger M. Wanner, Christian Mottet, Marc Girardin, Alain M. Schoepfer, Gerhard Rogler, Luc Biedermann, University of Zurich, and Girardin, Marc
- Subjects
medicine.medical_specialty ,First line ,Anti-Inflammatory Agents ,MEDLINE ,610 Medicine & health ,Disease ,Severity of Illness Index ,Gastroenterology ,Inflammatory bowel disease ,Crohn Disease ,Internal medicine ,Severity of illness ,Humans ,Medicine ,2715 Gastroenterology ,Colitis ,Crohn's disease ,business.industry ,Ileitis ,medicine.disease ,Ulcerative colitis ,digestive system diseases ,10219 Clinic for Gastroenterology and Hepatology ,Practice Guidelines as Topic ,Colitis, Ulcerative ,business - Abstract
Background and Aims: Medical therapy of inflammatory bowel disease (IBD) is becoming more complex, given the increasing choice of drugs to treat Crohn’s disease (CD) and ulcerative colitis (UC). We aimed to summarize the current guidelines for first-line treatments in IBD. Methods: An extensive literature search with focus on the guidelines of the European Crohn’s and Colitis Organisation for the diagnosis and treatment of CD and UC was performed. First-line treatments were defined as the following drug categories: 5-aminosalicylates, budesonide, systemic steroids, azathioprine, 6-mercaptopurine, methotrexate, infliximab, adalimumab and certolizumab pegol. The following drug categories were not included: cyclosporine and tacrolimus (not yet approved by Swissmedic for IBD treatment). Results: Treatment recommendations for the following clinically frequent situations are presented according to disease severity: ileocecal CD, colonic CD, proximal small bowel CD and perianal CD. For UC the following situations are presented: ulcerative proctitis, left-sided colitis and pancolitis. Conclusions: We provide a summary on the use of first-line therapies for clinically frequent situations in patients with CD and UC.
- Published
- 2012
47. Intolérances alimentaires et supervision de votre étudiant/interne : par où commencer ?
- Author
-
Rieder A, Junod Perron N, Girardin M, and Audétat MC
- Subjects
- Humans, Food Intolerance, Internship and Residency, Students, Medical
- Published
- 2020
48. Cohort Profile: The Swiss Eosinophilic Esophagitis Cohort Study (SEECS).
- Author
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Safroneeva E, Saner C, Rossel JB, Golay D, Pittet V, Godat S, Diem S, Aepli P, Sawatzki M, Borovicka J, Burgmann K, Juillerat P, Netzer P, Sendensky A, Hruz P, Girardin M, Biedermann L, Greuter T, Vavricka S, Michetti P, Mueller C, Straumann A, and Schoepfer AM
- Abstract
Background and Aims: The prospective, observational Swiss Eosinophilic Esophagitis Cohort Study (SEECS) was set up in 2015 with the following goals in mind: (1) to provide up-to-date epidemiologic data; (2) to assess the appropriateness of care; (3) to evaluate the psychosocial impact; and (4) to foster translational research projects. Data capture relies on validated instruments to assess disease activity and focuses on epidemiologic variables and biosamples (esophageal biopsies and blood specimens). An annual inclusion of 70 new patients with eosinophilic esophagitis (EoE) or proton pump inhibitor-responsive esophageal eosinophilia (PPI-REE) is intended. We herein describe the SEECS cohort profile., Methods: The SEECS includes adult patients (age ≥18 years) with EoE or PPI-REE diagnosed according to published criteria. After inclusion, the patients are typically seen once a year for a clinical and endoscopic/histologic follow-up examination. Data are captured using validated questionnaires. Biosamples from patients with gastroesophageal reflux disease (GERD) and controls with a healthy esophagus are collected as well., Results: From January 2016 to July 2017, a total of 111 patients with EoE and 10 patients with PPI-REE were recruited. In addition, esophageal biopsies and blood samples from 11 patients with GERD and 20 controls with a healthy esophagus were collected. The mean age of the patients with EoE and those with PPI-REE was 39.6 ± 12.9 and 44.6 ± 15.6 years, respectively. A male predominance was found among both the patients with EoE (77.5%) and those with PPI-REE (70%). Concomitant allergic disorders were found in 79.3% of the patients with EoE and 90% of the patients with PPI-REE. At inclusion, the EoE patients were treated with the following therapeutic regimens: no therapy (0.9%), PPI (36%), swallowed topical corticosteroids (82.9%), elimination diets (15.3%), and esophageal dilation (19.8%)., Conclusions: The SEECS is the first national cohort study of patients with EoE or PPI-REE. The SEECS will provide up-to-date epidemiologic data and foster translational research projects.
- Published
- 2018
- Full Text
- View/download PDF
49. [Pancreatic cancer in 2014: screening and epidemiology].
- Author
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Bochatay L, Girardin M, Bichard P, and Frossard JL
- Subjects
- Biomarkers analysis, CA-19-9 Antigen analysis, Carcinoembryonic Antigen analysis, Diagnostic Imaging, Humans, Pancreatic Neoplasms etiology, Risk Factors, Mass Screening, Pancreatic Neoplasms diagnosis, Pancreatic Neoplasms epidemiology
- Abstract
Pancreatic cancer remains today the cancer with the worst prognosis with 330300 deaths per year worldwide with a cancer prevalence of 211500 cases in 2012. Despite progress made in the understanding of the pathophysiology of this neoplasia, morbidity and mortality have not been modified. Tobacco remains the only modifiable risk factor with an impact on the incidence of pancreatic cancer. Screening programs involving medical imaging and serum markers have so far failed to alter the incidence and prognosis of the disease, even in selected populations with high risk. However, screening programs allowed some high-risk patients to be diagnosed early and therefore have been received care at an asymptomatic stage. The impact on the prognosis has nevertheless not been demonstrated yet.
- Published
- 2014
50. Monitoring disease activity and progression in Crohn's disease. A Swiss perspective on the IBD ahead 'optimised monitoring' recommendations.
- Author
-
Sauter B, Beglinger C, Girardin M, Macpherson A, Michetti P, Schoepfer A, Seibold F, Vavricka SR, and Rogler G
- Subjects
- Disease Progression, Endoscopy, Gastrointestinal, Humans, Crohn Disease diagnosis
- Abstract
Background and Aims: The structured IBD Ahead 'Optimised Monitoring' programme was designed to obtain the opinion, insight and advice of gastroenterologists on optimising the monitoring of Crohn's disease activity in four settings: (1) assessment at diagnosis, (2) monitoring in symptomatic patients, (3) monitoring in asymptomatic patients, and (4) the postoperative follow-up. For each of these settings, four monitoring methods were discussed: (a) symptom assessment, (b) endoscopy, (c) laboratory markers, and (d) imaging. Based on literature search and expert opinion compiled during an international consensus meeting, recommendations were given to answer the question 'which diagnostic method, when, and how often'. The International IBD Ahead Expert Panel advised to tailor this guidance to the healthcare system and the special prerequisites of each country. The IBD Ahead Swiss National Steering Committee proposes best-practice recommendations adapted for Switzerland., Methods: The IBD Ahead Steering Committee identified key questions and provided the Swiss Expert Panel with a structured literature research. The expert panel agreed on a set of statements. During an international expert meeting the consolidated outcome of the national meetings was merged into final statements agreed by the participating International and National Steering Committee members - the IBD Ahead 'Optimized Monitoring' Consensus., Results: A systematic assessment of symptoms, endoscopy findings, and laboratory markers with special emphasis on faecal calprotectin is deemed necessary even in symptom-free patients. The choice of recommended imaging methods is adapted to the specific situation in Switzerland and highlights the importance of ultrasonography and magnetic resonance imaging besides endoscopy., Conclusion: The recommendations stress the importance of monitoring disease activity on a regular basis and by objective parameters, such as faecal calprotectin and endoscopy with detailed documentation of findings. Physicians should not rely on symptoms only and adapt the monitoring schedule and choice of options to individual situations., (© 2014 S. Karger AG, Basel.)
- Published
- 2014
- Full Text
- View/download PDF
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