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Your search keyword '"Franki Speleman"' showing total 241 results

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241 results on '"Franki Speleman"'

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1. A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models

2. Long noncoding RNA expression profiling in cancer: Challenges and opportunities

3. A g316a polymorphism in the ornithine decarboxylase gene promoter modulates mycn‐driven childhood neuroblastoma

4. RRM2 is a target for synthetic lethal interactions with replication stress checkpoint addiction in high-risk neuroblastoma

5. Comprehensive benchmarking of single cell RNA sequencing technologies for characterizing cellular perturbation

6. Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development

7. Large-scale circular RNA deregulation in T-ALL: Unlocking unique ectopic expression of molecular subtypes

8. TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

9. A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia through polyA+ and total RNA sequencing

10. Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice

11. Cell of origin dictates aggression and stem cell number in acute lymphoblastic leukemia

12. Epigenetic regulation of neuroblastoma development

13. Abstract 2481: Time-resolved transcriptome analysis of murine TH-MYCN driven neuroblastoma identifies MEIS2 as early initiating factor and novel core gene regulatory circuitry constituent

14. Shallow Whole Genome Sequencing on Circulating Cell-Free DNA Allows Reliable Noninvasive Copy-Number Profiling in Neuroblastoma Patients

15. Comprehensive miRNA expression profiling in human T-cell acute lymphoblastic leukemia by small RNA-sequencing

16. Long non-coding RNAs in leukemia

17. Glutathione biosynthesis is upregulated at the initiation of MYCN-driven neuroblastoma tumorigenesis

18. PRL3 enhances T cell acute lymphoblastic leukemia growth through suppressing T cell signaling pathways and apoptosis

19. In silico discovery of a FOXM1 driven embryonal signaling pathway in therapy resistant neuroblastoma tumors

20. Purification of high-quality RNA from a small number of fluorescence activated cell sorted zebrafish cells for RNA sequencing purposes

21. Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients

22. PS920 PHF6 LOSS DRIVES IL7R ONCOGENE ADDICTION IN TLX1 DRIVEN T-ALL

23. Network Modeling of microRNA-mRNA Interactions in Neuroblastoma Tumorigenesis Identifies miR-204 as a Direct Inhibitor of MYCN

24. T-ALL and thymocytes: a message of noncoding RNAs

25. Early and late effects of pharmacological ALK inhibition on the neuroblastoma transcriptome

26. Targeting tachykinin receptors in neuroblastoma

27. Epigenetics in T-cell acute lymphoblastic leukemia

28. The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia

29. A nanobody modulates the p53 transcriptional program without perturbing its functional architecture

30. miR-542-3p exerts tumor suppressive functions in neuroblastoma by downregulating Survivin

31. The epigenetic landscape of T-cell acute lymphoblastic leukemia

32. RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer

33. Lack of association betweenMDM2promoter SNP309 and clinical outcome in patients with neuroblastoma

34. ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia

35. Abstract 3696: PHF6loss drives IL7R oncogene addiction in TLX1 driven T-ALL

36. Hyperdiploidy with 58-66 chromosomes in childhood B-acute lymphoblastic leukemia is highly curable: 58951 CLG-EORTC results

37. Novel TAL1 targets beyond protein-coding genes: identification of TAL1-regulated microRNAs in T-cell acute lymphoblastic leukemia

38. RT-qPCR gene expression analysis in zebrafish

39. DNA methylation profiling of primary neuroblastoma tumors using methyl-CpG-binding domain sequencing

40. Segmental chromosomal alterations have prognostic impact in neuroblastoma: a report from the INRG project

41. Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas

42. Copy number defects of G1-Cell cycle genes in neuroblastoma are frequent and correlate with high expression of E2F target genes and a poor prognosis

43. Neuroblastoma epigenetics: From candidate gene approaches to genome-wide screenings

44. Isolation of disseminated neuroblastoma cells from bone marrow aspirates for pretreatment risk assessment by array comparative genomic hybridization

45. A cooperative microRNA-tumor suppressor gene network in acute T-cell lymphoblastic leukemia (T-ALL)

46. Functional Analysis of the p53 Pathway in Neuroblastoma Cells Using the Small-Molecule MDM2 Antagonist Nutlin-3

47. PHF6 mutations in adult acute myeloid leukemia

48. NOTCH1 and FBXW7 mutations have a favorable impact on early response to treatment, but not on outcome, in children with T-cell acute lymphoblastic leukemia (T-ALL) treated on EORTC trials 58881 and 58951

49. Prognostic Impact of Gene Expression–Based Classification for Neuroblastoma

50. Chromosomal and MicroRNA Expression Patterns Reveal Biologically Distinct Subgroups of 11q− Neuroblastoma

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