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107 results on '"Figueiras, Francisco"'

1. Key Questions and Recent Research Advances on Harmful Algal Blooms in Eastern Boundary Upwelling Systems

Author

Pitcher, Grant C., Figueiras, Francisco G., Kudela, Raphael M., Moita, Teresa, Reguera, Beatriz, Ruiz-Villareal, Manuel, Caldwell, Martyn M., Series Editor, Díaz, Sandra, Series Editor, Heldmaier, Gerhard, Series Editor, Jackson, Robert B., Series Editor, Lange, Otto L., Series Editor, Levia, Delphis F., Series Editor, Mooney, Harold A., Series Editor, Schulze, Ernst-Detlef, Series Editor, Sommer, Ulrich, Series Editor, Glibert, Patricia M., editor, Berdalet, Elisa, editor, Burford, Michele A., editor, Pitcher, Grant C., editor, and Zhou, Mingjiang, editor

Published
2018
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15. Correction: Kulk et al. Primary Production, an Index of Climate Change in the Ocean: Satellite-Based Estimates over Two Decades. Remote Sens. 2020, 12, 826

Author

Kulk, Gemma, primary, Platt, Trevor, additional, Dingle, James, additional, Jackson, Thomas, additional, Jönsson, Bror F., additional, Bouman, Heather A., additional, Babin, Marcel, additional, Brewin, Robert J. W., additional, Doblin, Martina, additional, Estrada, Marta, additional, Figueiras, Francisco G., additional, Furuya, Ken, additional, González-Benítez, Natalia, additional, Gudfinnsson, Hafsteinn G., additional, Gudmundsson, Kristinn, additional, Huang, Bangqin, additional, Isada, Tomonori, additional, Kovač, Žarko, additional, Lutz, Vivian A., additional, Marañón, Emilio, additional, Raman, Mini, additional, Richardson, Katherine, additional, Rozema, Patrick D., additional, van de Poll, Willem H., additional, Segura, Valeria, additional, Tilstone, Gavin H., additional, Uitz, Julia, additional, van Dongen-Vogels, Virginie, additional, Yoshikawa, Takashi, additional, and Sathyendranath, Shubha, additional

Published
2021
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16. Assessing the effect of oil spills on the dynamics of the microbial plankton community using a NPZD model

Author

Gonzalez Fernandez, Jose, Fernández Suárez, Emilio Manuel, and Gómez Figueiras, Francisco

Subjects
2510.01 Oceanografía Biológica, 2417.05 Biología Marina, NPZD model, Upwelling, fungi, Oil spills, Pollution effects, Aquatic Science, Oceanography, Plankton, Mesocosms
Abstract

15 pages, 11 figures, 3 tables.-- Under a Creative Commons license, A mesocosms approach was used to assess the seasonal variability and the effect of oil spills on the structure and dynamics of marine microbial plankton communities in a coastal upwelling system. To this aim, four experiments were conducted during the main characteristic periods of the seasonal cycle in the Ría de Vigo (NW of Spain): spring phytoplankton bloom, summer stratification, autumn upwelling and winter mixing. In each of these experiments, enclosed communities in control and oiled bags were monitored and key variables and rates were measured during 9 days. Temporal changes in community structure and function were interpreted applying a simple NPZD (Nutrients-Phytoplankton-Zooplankton-Detritus) model in which the strategy was to maintain invariant as many model parameters as possible. The analysis of those parameters that were modified to accurately simulate the time evolution of the microbial communities in the mesocosms, provided important information about the main processes influencing the plankton community structure and dynamics in the bags as well as about the effect of oil. This modelling approach allowed assessing the dynamics of the four communities just varying phytoplankton maximum growth rates, bacterial growth efficiencies, microzooplankton grazing rates and phytoplankton sinking rates. Comparison of parameters in control and oiled bags in each period allowed to infer the negligible effect of oil spills on the structure and dynamics of the microbial plankton communities in this coastal upwelling system, This research was funded by the project IMPRESION (VEM2003-20021) of the Spanish Ministerio de Educación y Ciencia. J. G. was supported by a FPU fellowship of the Spanish Ministerio de Educación y Ciencia. Funding for open access charge: Universidade de Vigo/CISUG

Published
2021

19. Primary Production, an Index of Climate Change in the Ocean:Satellite-Based Estimates over Two Decades [+ correction]

Author

Kulk, Gemma, Platt, Trevor, Dingle, James, Jackson, Thomas, Jönsson, Bror F., Bouman, Heather A., Babin, Marcel, Brewin, Robert J. W., Doblin, Martina, Estrada, Marta, Figueiras, Francisco G., Furuya, Ken, González-benítez, Natalia, Gudfinnsson, Hafsteinn G., Gudmundsson, Kristinn, Huang, Bangqin, Isada, Tomonori, Kovač, Žarko, Lutz, Vivian A., Marañón, Emilio, Raman, Mini, Richardson, Katherine, Rozema, Patrick D., Poll, Willem H. Van De, Segura, Valeria, Tilstone, Gavin H., Uitz, Julia, Dongen-vogels, Virginie Van, Yoshikawa, Takashi, and Sathyendranath, Shubha

Published
2020
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21. Photosynthesis and light regime in the Azores Front region during summer: Are light-saturated computations of primary production sufficient?

Author

Lorenzo, Muisa. M., Figueiras, Francisco G., Tilstone, Gavin H., Arbones, Belen, and Miron, Ivan

Subjects
Oceanography -- Models, Primary productivity (Biology) -- Analysis, Photosynthesis -- Research, Earth sciences
Abstract

Bio-optical variables for primary production (PP) computations were determined at the Azores front (AF) (30-38 degree C N to 20-23 degree W). Modeling primary production in stratified oceans with permanent DCM could be greatly simplified by ignoring the spectral resolution and indicates that further effort should be focused on characterizing and predicting the spatial and temporal variations in chlorophyll-specific maximum photosynthetic rates in these vast oligotrophic oceanic regions.

Published
2004

23. Primary Production, an Index of Climate Change in the Ocean: Satellite-Based Estimates over Two Decades

Author

Kulk, Gemma, primary, Platt, Trevor, additional, Dingle, James, additional, Jackson, Thomas, additional, Jönsson, Bror, additional, Bouman, Heather, additional, Babin, Marcel, additional, Brewin, Robert, additional, Doblin, Martina, additional, Estrada, Marta, additional, Figueiras, Francisco, additional, Furuya, Ken, additional, González-Benítez, Natalia, additional, Gudfinnsson, Hafsteinn, additional, Gudmundsson, Kristinn, additional, Huang, Bangqin, additional, Isada, Tomonori, additional, Kovač, Žarko, additional, Lutz, Vivian, additional, Marañón, Emilio, additional, Raman, Mini, additional, Richardson, Katherine, additional, Rozema, Patrick, additional, Poll, Willem, additional, Segura, Valeria, additional, Tilstone, Gavin, additional, Uitz, Julia, additional, Dongen-Vogels, Virginie, additional, Yoshikawa, Takashi, additional, and Sathyendranath, Shubha, additional

Published
2020
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32. Photosynthesis–irradiance parameters of marine phytoplankton: synthesis of a global data set

Author

Bouman, Heather A., primary, Platt, Trevor, additional, Doblin, Martina, additional, Figueiras, Francisco G., additional, Gudmundsson, Kristinn, additional, Gudfinnsson, Hafsteinn G., additional, Huang, Bangqin, additional, Hickman, Anna, additional, Hiscock, Michael, additional, Jackson, Thomas, additional, Lutz, Vivian A., additional, Mélin, Frédéric, additional, Rey, Francisco, additional, Pepin, Pierre, additional, Segura, Valeria, additional, Tilstone, Gavin H., additional, van Dongen-Vogels, Virginie, additional, and Sathyendranath, Shubha, additional

Published
2018
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35. Diatoms as a paleoproductivity proxy in the NW Iberian coastal upwelling system (NE Atlantic)

Author

Zuniga, Diana, Santos, Celia, Frojan, Maria, Salgueiro, Emilia, Rufino, Marta, De La Granda, Francisco, Figueiras, Francisco G., Castro, Carmen G., Abrantes, Fatima, Zuniga, Diana, Santos, Celia, Frojan, Maria, Salgueiro, Emilia, Rufino, Marta, De La Granda, Francisco, Figueiras, Francisco G., Castro, Carmen G., and Abrantes, Fatima

Abstract

The objective of the current work is to improve our understanding of how water column diatom's abundance and assemblage composition is seasonally transferred from the photic zone to seafloor sediments. To address this, we used a dataset derived from water column, sediment trap and surface sediment samples recovered in the NW Iberian coastal upwelling system. Diatom fluxes (2.2 (+/- 5.6) 10(6) valves m(-2) d(-1)) represented the majority of the siliceous microorganisms sinking out from the photic zone during all studied years and showed seasonal variability. Contrasting results between water column and sediment trap diatom abundances were found during downwelling periods, as shown by the unexpectedly high diatom export signals when diatom- derived primary production achieved their minimum levels. They were principally related to surface sediment remobilization and intense Minho and Douro river discharge that constitute an additional source of particulate matter to the inner continental shelf. In fact, contributions of allochthonous particles to the sinking material were confirmed by the significant increase of both benthic and freshwater diatoms in the sediment trap assemblage. In contrast, we found that most of the living diatom species blooming during highly productive upwelling periods were dissolved during sinking, and only those resistant to dissolution and the Chaetoceros and Leptocylindrus spp. resting spores were susceptible to being exported and buried. Fur-thermore, Chaetoceros spp. dominate during spring-early summer, when persistent northerly winds lead to the upwelling of nutrient-rich waters on the shelf, while Leptocylindrus spp. appear associated with late-summer upwelling relaxation, characterized by water column stratification and nutrient depletion. These findings evidence that the contributions of these diatom genera to the sediment's total marine diatom assemblage should allow for the reconstruction of different past upwelling regimes.

Published
2017
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36. Photosynthesis-irradiance parameters of marine phytoplankton: synthesis of a global data set

Author

Bouman, Heather A., primary, Platt, Trevor, additional, Doblin, Martina, additional, Figueiras, Francisco G., additional, Gudmudsson, Kristinn, additional, Gudfinnsson, Hafsteinn G., additional, Huang, Bangqin, additional, Hickman, Anna, additional, Hiscock, Michael, additional, Jackson, Thomas, additional, Lutz, Vivian A., additional, Mélin, Frédéric, additional, Rey, Francisco, additional, Pepin, Pierre, additional, Segura, Valeria, additional, Tilstone, Gavin H., additional, van Dongen-Vogels, Virginie, additional, and Sathyendranath, Shubha, additional

Published
2017
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38. Response of prokaryotic and eukaryotic community structure to inorganic and organic nutrient additions in a eutrophic coastal ecosystem

Author

G Teixeira Isabel, Barber-Lluch Esther, Arbones Belén, Hernández-Ruiz Marta, Fernandez Suarez Emilio, Sobrino Cristina, Álvarez-Salgado Xosé, Teira Eva, Nieto-Cid Mar, and G Figueiras Francisco

Subjects
Global and Planetary Change, lcsh:QH1-199.5, Ecology, Community structure, eukaryotic diversity, Ocean Engineering, lcsh:General. Including nature conservation, geographical distribution, Aquatic Science, Microcosm Experiment, prokaryotic diversity, Oceanography, Nutrient, ARISA, Coastal ecosystem, Nutrient additions, Environmental science, lcsh:Q, lcsh:Science, Eutrophication, Water Science and Technology
Abstract

Coastal oceans are known to receive increasing inputs of reactive N as a result of the anthropogenic alteration of N cycling at the global scale, which may greatly alter nutrient supply to microbial plankton communities. The influence of nutrient availability (mainly inorganic N and P and/or organic C) on species composition has been widely reported for both eukaryotes and prokaryotes. The Ría de Vigo is a eutrophic embayment located in the coastal system of the NW Iberian Peninsula. Previous studies in the area revealed a highly variable response of microbial plankton to nutrient additions, a strong stimulation of phytoplankton growth after inorganic (N and P) and organic (C and N) nutrient addition and a strong carbon limitation of bacterial activity. To gain understanding on the effect of nutrient inputs on the functioning of this coastal ecosystem, the short-term effects of inorganic N and P (nitrate, ammonium, phosphate) and organic C and N (glucose, amino acids) inputs, added separately as well as jointly, on eukaryotic and prokaryotic community composition were studied in microcosm experiments conducted under contrasting hydrographic conditions. Changes in microbial diversity were analyzed by ARISA (automatic rRNA intergenic spacer analysis) and two sets of primers specific for bacteria and eukaryotes. The results obtained in these experiments showed that changes in microbial communities were clearly determined by the initial microbial assemblage. Changes in prokaryotic and eukaryotic community composition were closely related to changes in metabolic rates. In contrast to previous observations, prominent changes in bacterial community composition occurred only after inorganic and organic nutrient additions, which suggest a C and P co-limitation of bacteria during the sampling periods. Major eukaryotic community composition changes were observed in response to inorganic additions.

Published
2014
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39. Marine Primary Productivity Is Driven by a Selection Effect

Author

Cermeño, Pedro, primary, Chouciño, Paloma, additional, Fernández-Castro, Bieito, additional, Figueiras, Francisco G., additional, Marañón, Emilio, additional, Marrasé, Cèlia, additional, Mouriño-Carballido, Beatriz, additional, Pérez-Lorenzo, María, additional, Rodríguez-Ramos, Tamara, additional, Teixeira, Isabel G., additional, and Vallina, Sergio M., additional

Published
2016
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41. Iberian margins: The Rias

Author

Álvarez-Salgado, Xosé Antón, Borges, Alberto Vieira, Figueiras, Francisco, Chou, Lei, Álvarez-Salgado, Xosé Antón, Borges, Alberto Vieira, Figueiras, Francisco, and Chou, Lei

Abstract

info:eu-repo/semantics/published

Published
2010

43. Diatoms as paleoproductivity proxy in the NW Iberian coastal upwelling system (NE Atlantic).

Author

Zúñiga, Diana, Santos, Celia, Froján, María, Salgueiro, Emilia, Rufino, Marta M., De la Granda, Francisco, Figueiras, Francisco G., Castro, Carmen G., and Abrantes, Fátima

Subjects
DIATOMS, PLANT species, OCEAN bottom, MARINE sediments, PALEOCEANOGRAPHY, GLOBAL warming, WATER temperature
Abstract

The objective of the current work is to better understand how diatoms species determine primary production signal in exported and buried particles. We evaluated how the diatom's abundance and assemblage composition is transferred from the photic zone into the seafloor sediments. A combined analysis of water column, sediment trap and surface sediment samples recovered in the NW Iberian coastal upwelling system was used. Diatom fluxes (2.2 ± 5.6 106 # valves m-2 d-1) represented the majority of the siliceous microorganisms sinking out from the photic zone and showed strong seasonal variability. During downwelling seasons, diatoms export signal was strongly affected by resuspension of bottom sediments and intense Minho and Douro riverine inputs, with benthic and freshwater diatoms (17-24%) becoming relevant in the sediment trap assemblage. Nevertheless, during upwelling productive seasons, the diatoms exported out from surface layer reflected water column diatom assemblage. They were principally represented by Chaetoceros spp. (mean 46 ± 25%) and Leptocylindrus spp. (mean 20 ± 22%) resting spores, demonstrating that both groups are a good sedimentary imprint during highly productive periods. Moreover, our data showed that the sink of Chaetoceros spp. resting spores dominated under persistent upwelling winds, high irradiance levels and cold and nutrient-rich waters. Otherwise, Leptocylindrus spp. spore fluxes were favoured when northerly winds relax, and surface waters warming promotes water column stratification. Further, this finding will provide a proxy of persistent vs. intermittent upwelling conditions, which is of particular relevance in palaeoceanography. [ABSTRACT FROM AUTHOR]

Published
2016
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44. Thermohaline, chemical and biological characterisation of the poleward flowing Portugal coastal counter current off NW Spain

Author

Álvarez-Salgado, Xosé Antón, Figueiras, Francisco, Pérez, F.F., Groom, Steve, Nogueira, Enrique, Borges, Alberto Vieira, Chou, Lei, Castro, C.G., Moncoiffe, Gwenaëlle, Rios, A F, Miller, A.EJ., Frankignoulle, M., Savidge, Graham, Wollast, Roland, Álvarez-Salgado, Xosé Antón, Figueiras, Francisco, Pérez, F.F., Groom, Steve, Nogueira, Enrique, Borges, Alberto Vieira, Chou, Lei, Castro, C.G., Moncoiffe, Gwenaëlle, Rios, A F, Miller, A.EJ., Frankignoulle, M., Savidge, Graham, and Wollast, Roland

Abstract

info:eu-repo/semantics/published

Published
2004

45. The Portugal coastal counter current off NW Spain: New insights on its biogeochemical variability

Author

Álvarez-Salgado, Xosé Antón, Figueiras, Francisco, Pérez, F.F., Groom, Steve, Nogueira, Enrique, Borges, Alberto Vieira, Chou, Lei, Castro, C.G., Moncoiffe, Gwenaëlle, Ríos, Aída, Miller, Axel, Frankignoulle, Michel, Savidge, Graham, Wollast, Roland, Álvarez-Salgado, Xosé Antón, Figueiras, Francisco, Pérez, F.F., Groom, Steve, Nogueira, Enrique, Borges, Alberto Vieira, Chou, Lei, Castro, C.G., Moncoiffe, Gwenaëlle, Ríos, Aída, Miller, Axel, Frankignoulle, Michel, Savidge, Graham, and Wollast, Roland

Abstract

Time series of wind-stress data, AVHRR and SeaWiFS satellite images, and in situ data from seven cruises are used to assemble a coherent picture of the hydrographic variability of the seas off the Northwest Iberian Peninsula from the onset (September-October) to the cessation (February-May) of the Portugal coastal counter current (PCCC). During this period the chemistry and the biology of the shelf, slope and ocean waters between 40° and 43°N have previously been undersampled. Novel information extracted from these observations relate to: 1. The most frequent modes of variability of the alongshore coastal winds, covering event, seasonal and long-term scales; 2. The conspicuous cycling between stratification and homogenisation observed in PCCC waters, which has key implications for the chemistry and biology of these waters; 3. The seasonal evolution of nitrite profiles in PCCC waters in relation to the stratification cycle; 4. The Redfield stoichiometry of the remineralisation of organic matter in Eastern North Atlantic Central Water (ENACW) - the water mass being transported by the PCCC; 5. The separation of coastal (mesotrophic) from PCCC (oligotrophic) planktonic populations by a downwelling front along the shelf, which oscillates to and fro across the shelf as a function of coastal wind intensity and continental runoff; and 6. The photosynthetic responses of the PCCC and coastal plankton populations to the changing stratification and light conditions from the onset to the cessation of the PCCC. © 2003 Elsevier Science Ltd. All rights reserved., SCOPUS: re.j, info:eu-repo/semantics/published

Published
2003

48. Initial Invasive or Conservative Strategy for Stable Coronary Disease

Author

Maron D. J., Hochman J. S., Reynolds H. R., Bangalore S., O'Brien S. M., Boden W. E., Chaitman B. R., Senior R., Lopez-Sendon J., Alexander K. P., Lopes R. D., Shaw L. J., Berger J. S., Newman J. D., Sidhu M. S., Goodman S. G., Ruzyllo W., Gosselin G., Maggioni A. P., White H. D., Bhargava B., Min J. K., John Mancini G. B., Berman D. S., Picard M. H., Kwong R. Y., Ali Z. A., Mark D. B., Spertus J. A., Krishnan M. N., Elghamaz A., Moorthy N., Hueb W. A., Demkow M., Mavromatis K., Bockeria O., Peteiro J., Miller T. D., Szwed H., Doerr R., Keltai M., Selvanayagam J. B., Gabriel Steg P., Held C., Kohsaka S., Mavromichalis S., Kirby R., Jeffries N. O., Harrell F. E., Rockhold F. W., Broderick S., Bruce Ferguson T., Williams D. O., Harrington R. A., Stone G. W., Rosenberg Y, ISCHEMIA Research Group: Joseph Ricci, A Tello Montoliu, A I Robero Aniorte, Abbey Mulder, Abhay A Laddu, Abhinav Goyal, Abhishek Dubey, Abhishek Goyal, Abigail Knighton, Abraham Oomman, Adam J Jaskowiak, Adam Kolodziej, Adam Witkowski, Adnan Hameed, Adriana Anesini, Afshan Hussain, Agne Juceviciene, Agne Urboniene, Agnes Jakal, Agnieszka Szramowska, Ahmad Khairuddin, Ahmed Abdel-Latif, Ahmed Adel, Ahmed Aljzeeri, Ahmed Kamal, Ahmed Talaat, Aimee Mann, Aira Contreras, Ajit Kumar, V K Kumar, Akemi Furukawa, Akshay Bagai, Akvile Smigelskaite, Alain Furber, Alain Rheault, Alaine Melanie Loehr, Alan Rosen, Albert Varga, Albertina Qelaj, Alberto Barioli, Aldo Russo, Alec Moorman, Alejandro Gisbert, Aleksandra Fratczak, Aleksandras Laucevicius, Alena Kuleshova, Alessandro Sionis, Alexander A Sirker, Alexander M Chernyavskiy, Alexandra Craft, Alexandra Vazquez, Alexandre Ciappina Hueb, Alexandre S Colafranseschi, Alexandre Schaan de Quadros, Alexandre Tognon, Ali Alghamdi, Alice Manica Muller, Aline Nogueira Rabaça, Aline Peixoto Deiro, Alison Hallam, Allegra Stone, Allison Schley, Almudena Castro, Alvaro Rabelo Ales, Amanda Germann, Amanda O'Malley, Amar Uxa, Amarachi Ojajuni, Amarino C Oliveira Jr, Amber B Hull, Ambuj Roy, Amer Zarka, Amir Janmohamed, Ammani Brown, Ammy Malinay, Amparo Martinez Monzonis, Amy J Richards, Amy Iskandrian, Amy Ollinger, Ana D Djordjevic-Dikic, Ana Fernández Martínez, Ana Gomes Almeida, Ana Paula Batista, Ana Rita Francisco, Ana S Mladenovic, Ana Santana, Anam Siddiqui, Anastasia M Kuzmina-Krutetskaya, Andras Vertes, Andre S Sousa, Andre Gabriel, André Schmidt, Andrea M Lundeen, Andrea Bartykowszki, Andrea Lorimer, Andrea Mortara, Andrea Pascual, Andreia Coelho, Andreia Rocha, Andrés García-Rincón, Andrew G Howarth, Andrew J Moriarty, Andrew Docherty, Andrew Starovoytov, Andrew Zurick, Andrzej Łabyk, Andrzej Swiatkowski, Andy Lam, Anelise Kawakami, Angela Hoye, Angela Kim, Angelique Smit, Angelo Nobre, Anil V Shah, Anja Ljubez, Anjali Anand, Ankush Sachdeva, Ann Greenberg, Ann Luyten, Ann Ostrander, Anna Di Donato, Anna Cichocka-Radwan, Anna Fojt, Anna Plachcinska, Anna Proietti, Anna Teresinska, Anne Marie Webb, Anne Cartwright, Anne Heath, Anne Mackin, Anong Amaritakomol, Anong Chaiyasri, Anoop Chauhan, Anoop Mathew, Anthony Gemignani, Anto Luigi Andres, Antonia Vega, Antonietta Hansen, Antonino Ginel Iglesias, Antonio Carlos Carvalho, Antonio Di Chiara, Antonio Serra Peñaranda, Antonio Carvalho, Antonio Colombo, Antonio Fiarresga, Anupama Rao, Aquiles Valdespino-Estrada, Araceli Boan, Areef Ishani, Ariel Diaz, Arijit Ghosh, Arintaya Prommintikul, Arline Roberts, Arnold H Seto, Arnold P Good, Arshed Quyyumi, Arthur J Labovitz, Arthur Kerner, Arturo S Campos-Santaolalla, Arunima Misra, Ashok Mukherjee, Ashok Seth, Ashraf Seedhom, Asim N Cheema, Asker Ahmed, Atul Mathur, Atul Verma, Audrey W Leong, Axel Åkerblom, Axelle Fuentes, Aynun Naher, Badhma Valaiyapathi, Baljeet Kaur, Bandula Guruge, Barbara Brzezińska, Barbara Nardi, Bartosz Czarniak, Bebek Singh, Begoña Igual, Bela Merkely, Belen Cid Alvarez, Benjamin J Spooner, Benjamin J W Chow, Benjamin Cheong, Benoy N Shah, Bernard de Bruyne, Bernardas Valecka, Bernhard Jäger, Beth A Archer, Beth Abramson, Beth Jorgenson, Bethany Harvey, Betsy O'Neal, Bev Atkinson, Bev Bozek, Bevin Lang, Bijulal Sasidharan, Bin Yang, Bin Zhang, Binoy Mannekkattukudy Kurian, Bjoern Goebel, Bob Hu, Bogdan A Popescu, Bogdan Crnokrak, Bolin Zhu, Bonnie J Kirby, Brandi D Zimbelman, Brandy Starks, Branko D Beleslin, Brenda Hart, Brian P Shapiro, Brian McCandless, Brianna Wisniewski, Brigham R Smith, Brooks Mirrer, Bruce McManus, Bruce Rutkin, Bruna Edilena Paulino, Bruna Maria Ascoli, Bryn Smith, Byron J Allen, C Michael Gibson, C Noel Bairey Merz, Calin Pop, Cameron Hague, Camila Thais de Ormundo, Candace Gopaul, Candice P Edillo, Carísi A Polanczyk, Carita Krannila, Carla Vicente, Carl-Éric Gagné, Carlo Briguori, Carlos Peña Gil, Carlos Alvarez, Carly Ohmart, Carmen C Beladan, Carmen Ginghina, Carol M Kartje, Caroline Alsweiler, Caroline Brown, Caroline Callison, Caroline Pinheiro, Caroline Rodgers, Caroline Spindler, Carolyn Corbett, Carrie Drum, Casey Riedberger, Catherine Bone, Catherine Fleming, Catherine Gordon, Catherine Jahrsdorfer, Catherine Lemay, Catherine Weick, Cathrine Patten, Cecilia Goletto, Cezary Kepka, Chandini Suvarna, Chang Xu, Chantale Mercure, Charle A Viljoen, Charlene Wiyarand, Charles Jia-Yin Hou, Charles Y Lui, Charles Cannan, Charles Cornet, Charlotte Pirro, Chataroon Rimsukcharoenchai, Chen Wang, Cheng-Ting Tsai, Chen-Yen Chien, Cheryl A Allardyce, Chester M Hedgepeth, Chetan Patel, Chiara Attanasio, Chih-Hsuan Yen, Chi-Ming Chow, Ching Min Er, Ching-Ching Ong, Cholenahally Nanjappa Manjunath, Chris Beck, Chris Buller, Christel Vassaliere, Christian Hamm, Christiano Caldeira, Christie Ballantyne, Christina Björklund, Christine R Hinton, Christine Bergeron, Christine Masson, Christine Roraff, Christine Shelley, Christophe Laure, Christophe Thuaire, Christopher Kinsey, Christopher McFarren, Christopher Spizzieri, Christopher Travill, Chun-Chieh Liu, Chung-Lieh Hung, Chunguang Li, Chun-Ho Yun, Chunli Xia, Ciarra Heard, Cidney Schultz, Clare Venn-Edmonds, Claudia P Hochberg, Claudia Wegmayr, Claudia Cortés, Claudia Escobar, Cláudia Freixo, Claudio T Mesquita, Clemens T Kadalie, Colin Berry, Constance Philander, Corine Thobois, Costantino Costantini, Courtney Page, Craig Atkinson, Craig Barr, Craig Paterson, Cristina Bare, Cynthia Baumann, Cynthia Burman, Dalisa Espinosa, Damien Collison, Dan Deleanu, Dan Elian, Dan Gao, Dana Oliver, Daniel P Vezina, Daniel O'Rourke, Daniele Komar, Danielle Schade, Darrel P Francis, Dastan Malaev, David A Bull, David E Winchester, David P Faxon, David Booth, David Cohen, David DeMets, David Foo, David Schlichting, David Taggart, David Waters, David Wohns, Davis Vo, Dawid Teodorczyk, Dawn Shelstad, Dawn Turnbull, Dayuan Li, Dean Kereiakes, Deborah O'Neill, Deborah Yip, Debra K Johnson, Debra Dees, Deepak L Bhatt, Deepika Gopal, Deepti Kumar, Deirdre Mattina, Deirdre Murphy, Delano R Small, Delsa K Rose, Dengke Jiang, Denis Carl Phaneuf, Denise Braganza, Denise Fine, Derek Cyr, Desiree Tobin, Diana Cukali, Diana Parra, Diane Camara, Diane Minshall Liu, Diego Adrián Vences, Diego Franca de Cunha, Dimitrios Stournaras, Dipti Patel, Dongze Li, Donna Exley, Dorit Grahl, Dragana Stanojevic, Duarte Cacela, Dwayne S G Conway, E Pinar Bermudez, Eapen Punnoose, Edgar L Tay, Edgar Karanjah, Edoardo Verna, Eduardo Hernandez-Rangel, Edward D Nicol, Edward O McFalls, Edward T Martin, Edyta Kaczmarska, Ekaterina I Lubinskaya, Elena A Demchenko, Elena Refoyo Salicio, Eli Feen, Elihú Durán-Cortés, Elisabeth M Janzen, Elise L Hannemann, Elise van Dongen, Elissa Restelli Piloto, Eliza Kaplan, Elizabeta Srbinovska Kostovska, Elizabeth Capasso-Gulve, Elizabeth Congdon, Elizabeth Ferguson, Elizaveta V Zbyshevskaya, Ellen Magedanz, Ellie Fridell, Ellis W Lader, Elvin Kedhi, Emanuela Racca, Emilie Tachot, Emily DeRosa, Encarnación Alonso-Álvarez, Eric Nicollet, Eric Peterson, Erick Alexánderson Rosas, Erick Donato Morales, Erin Orvis, Ermina Moga, Estelle Montpetit, Estevao Figueiredo, Eugene Passamani, Eugenia Nikolsky, Eunice Yeoh, Evgeniy I Kretov, Ewa Szczerba, Ewelina Wojtala, Expedito Eustáquio Ribeiro Silva, F Marin Ortuño, Fabio R Farias, Fabio Fimiani, Fabrizio Rolfo, Fa-Chang Yu, Fadi Hage, Fadi Matar, Fahim Haider Jafary, Fang Feng, Fang Liu, Fatima Ranjbaran, Fatima Rodriguez, Fausto J Pinto, Fauzia Rashid, Federica Ramani, Fei Wang, Fernanda Igansi, Filipa Silva, Filippo Ottani, Fiona Haines, Firas Al Solaiman, Flávia Egydio, Flavio Lyra, Florian Egger, Fran Farquharson, Frances Laube, Francesc Carreras Costa, Francesca de Micco, Francesca Bianchini, Francesca Pezzetta, Francesca Pietrucci, Francesco Orso, Francesco Pisano, Francis Burt, Francisca Patuleia Figueiras, Francisco Fernandez-Aviles, Francois Pierre 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S.G., Ruzyllo W., Gosselin G., Maggioni A.P., White H.D., Bhargava B., Min J.K., John Mancini G.B., Berman D.S., Picard M.H., Kwong R.Y., Ali Z.A., Mark D.B., Spertus J.A., Krishnan M.N., Elghamaz A., Moorthy N., Hueb W.A., Demkow M., Mavromatis K., Bockeria O., Peteiro J., Miller T.D., Szwed H., Doerr R., Keltai M., Selvanayagam J.B., Gabriel Steg P., Held C., Kohsaka S., Mavromichalis S., Kirby R., Jeffries N.O., Harrell F.E., Rockhold F.W., Broderick S., Bruce Ferguson T., Williams D.O., Harrington R.A., Stone G.W., Rosenberg Y, and ISCHEMIA Research Group: Joseph Ricci, A Tello Montoliu, A I Robero Aniorte, Abbey Mulder, Abhay A Laddu, Abhinav Goyal, Abhishek Dubey, Abhishek Goyal, Abigail Knighton, Abraham Oomman, Adam J Jaskowiak, Adam Kolodziej, Adam Witkowski, Adnan Hameed, Adriana Anesini, Afshan Hussain, Agne Juceviciene, Agne Urboniene, Agnes Jakal, Agnieszka Szramowska, Ahmad Khairuddin, Ahmed Abdel-Latif, Ahmed Adel, Ahmed Aljzeeri, Ahmed Kamal, Ahmed Talaat, Aimee Mann, 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Bermudez, Eapen Punnoose, Edgar L Tay, Edgar Karanjah, Edoardo Verna, Eduardo Hernandez-Rangel, Edward D Nicol, Edward O McFalls, Edward T Martin, Edyta Kaczmarska, Ekaterina I Lubinskaya, Elena A Demchenko, Elena Refoyo Salicio, Eli Feen, Elihú Durán-Cortés, Elisabeth M Janzen, Elise L Hannemann, Elise van Dongen, Elissa Restelli Piloto, Eliza Kaplan, Elizabeta Srbinovska Kostovska, Elizabeth Capasso-Gulve, Elizabeth Congdon, Elizabeth Ferguson, Elizaveta V Zbyshevskaya, Ellen Magedanz, Ellie Fridell, Ellis W Lader, Elvin Kedhi, Emanuela Racca, Emilie Tachot, Emily DeRosa, Encarnación Alonso-Álvarez, Eric Nicollet, Eric Peterson, Erick Alexánderson Rosas, Erick Donato Morales, Erin Orvis, Ermina Moga, Estelle Montpetit, Estevao Figueiredo, Eugene Passamani, Eugenia Nikolsky, Eunice Yeoh, Evgeniy I Kretov, Ewa Szczerba, Ewelina Wojtala, Expedito Eustáquio Ribeiro Silva, F Marin Ortuño, Fabio R Farias, Fabio Fimiani, Fabrizio Rolfo, Fa-Chang Yu, Fadi Hage, Fadi Matar, Fahim Haider 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Niedzwiecka, J David Knight, Jacek Kusmierek, Jackie M White, Jackie Chow, Jacob Udell, Jacqueline E Tamis-Holland, Jacqueline Fannon, Jacquelyn A Quin, Jacquelyn Do, Jaekyeong Heo, Jakub Maksym, James E Davies, James H O'Keefe Jr, James J Jang, James Cha, James Harrison, James Hirsch, James Stafford, James Tatoulis, Jamie Rankin, Jan Henzel, Jan Orga, Jana Tancredi, Janaina Oliveira, Jane Burton, Jane Eckstein, Jane Marucci, Janet P Knight, Janet Blount, Janet Halliday, Janetta Kourzenkova, Janitha Raj, Jan-Malte Sinning, Jaqueline Pozzibon, Jaroslaw Drozdz, Jaroslaw Karwowski, Jason D Glover, Jason Loh Kwok, Jason T Call, Jason Linefsky, Jassira Gomes, Jati Anumpa, Javier J Garcia, Javier Courtis, Jay Meisner, K Jayakumar, Jayne Scales, Jean E Denaro, Jean Michel Juliard, Jean Ho, Jeanette K Stansborough, Jean-Michel Juliard, Jeanne Russo, Jeannette J M Schoep, Jeet Thambyrajah, Jeff Leimberger, Jeffery A Breall, Jeffrey A Kohn, Jeffrey C Milliken, Jeffrey Anderson, Jeffrey Blume, 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Natalia S Oliveira, Natalia de Carvalho Maffei, Natalie Spitzer, Natasha C Putnam, Naved Aslam, Neamat Mowafy, Neeraj Pandit, Neeraj Parakh, Nevena Garcevic, Ngaire Meadows, Nhi N Tran, Nicholas Danchin, Nicki Lakeman, Nicola Johnston, Nicolas W Shammas, Nicole Saint Vrestil, Nicole Deming, Nier Zhong, Niket Patel, Nikola N Boskovic, Nikolaos Karogiannis, Nikos Werner, Nina Johnston, Ning Zhang, Ning Zhou, Niree Hindoyan, Nirmal Kumar, Nitika Chadha, Nitish Naik, Nodira Aripova, Noloyiso Mtana, Nona A Eskelson, Noor Syamira Mokhtar, Noppon Taksaudom, Nor Asiah Basri, Nora Marchelletta, Norma Hogg, Nungshi Jungla, Nuno Ferreira, Oksana A Lubyanaya, Olga B Nikolaeva, Olga Cañavate, Olga Sobrino, Olga Walesiak, Olga Walter, Olga Zdończyk, Olivia J Lim, Olivia Anaya, Olivia Mancilla, Olivier Dubourg, Olugbenga Bello, Omar Almousalli, Omar Thompson, Oni Olurinde, Or Harel, Osama Raheem, Oscar Méndiz, Óscar Prada-Delgado, Oz Shapira, P Christian Schulze, Pachara Panpunuan, Pal Maurovich-Horvat, Pallav Garg, Paloma Moraga, Pam Singh, Pamela Julian, Pamela Ouyang, Pamela Sigel, Pamela Woodard, Panpan Zhou, Paola Emanuela Poggio, Paola Smanio, Paolo Calabro, Paramjit Jeetley, Pascal Goube, Patricia K Nguyen, Patricia Alarie, Patricia Arakelian, Patricia Arsenault, Patricia Blaise, Patricia Brito, Patricia Cowper, Patricia Endsley, Patricia Mieses, Patrick B Alexander, Patrick Donnelly, Patrick Wilmot, Patrycja Lebioda, Paul C Gordon, Paul Der Mesropian, Paul Galiwango, Paul Hauptman, Paul Kennedy, Paula Beardsley, Paula García-González, Paulo Cury Rezende, Paulo Ricardo Caramori, Pavel S Kozlov, Pedro Canas Silva, Pedro Gabriel Melo Barros E Silva, Pedro Píccaro de Oliveira, Pedro Carvalho, Pedro Modas, Pedro Rio, Peeyush Jain, Peiyu He, Peter A McCullough, Peter H Stone, Peter M Pollak, Peter Douglass, Peter Henriksen, Peter OKane, Peter Ong, Philip Jones, Philip Rogal, Philippe Généreux, Philippe Menasche, Philippe Rheault, Phoebe Goold, Pierre Gervais, Pierre Michaud, Pilar Calvillo, Ping Chai, Piotr Jakubowski, Piotr Pruszczyk, Piotr Slomka, Piyamitr Sritara, Poay-Huan Loh, Poonam Sonawane, Pouneh Samadi, Pragnesh P Parikh, Prakash Deedwania, Pranav M Patel, Praneeth Polamuri, Pratiksha Sharma, Precilia Vasquez, Preeti Kamath, Prince Thomas, Priyadarshani Arambam, Puja K Mehta, Purvez Grant, Pushpa Naik, Qi Zhong, Qian Zhao, Qiang Zhou, Qianqian Yuan, Qin Yu, Qingxian Li, Qiulan Xie, Qiutang Zeng, R J Vindhya, R James Gerlach, Rachel King, Rada Vučić, Radmila Lyubarova, Radoslaw Pracon, Raewyn Fisher, Rafael Beyar, Rafael Diaz, Rafael Selgas, Raffaele Bugiardini, Raffaele Fanelli, Raisa Kavalakkat, V S Rajalekshmi, Rajat S Barua, Rajeev Menon, Rajesh Gopalan Nair, Rajesh Francis, Rajiv Narang, Rakesh Yadav, Ralph Alan Huston, T Ramakrishnan, Ramesh de Silva, Rami El Mahmoud, Ramiro Carvalho, Ramon de Jesús-Pérez, Ramona Stevens, Ran Leng, Ranjan Kachru, Ranjit Kumar Nath, Raquel Sanchez, Raven R Dwyer, Raven Lee, Ray Wyman, Raymond C Wong, Raymond W Little, Raymundo Ocaranza Sanchez, Rebecca J Wimmer, Rebecca Bariciano, Rebecca Otis, Rebekah R Herrmann, Reem Yunis, Reinette Hampson, Renato Abdala Karam, Renee C Hessian, Renee Kaneshiro, Reshma Ravindran, Reto Andreas Gamma, Reyna Bhandari, Reza Arsanjani, Ricardo L Lopes, Ricardo Mendes Oliveira, Ricardo Costa, Richa Bhatt, Richard F Davies, Richard H J Trimlett, Richard Goldweit, Rik Hermanides, Rine Nakanishi, Rinu R Sidh, Risha Patel, Rita Coram, Rizwan A Siddiqui, Rob S Beanlands, Robert J Hamburger, Robert K Riezebos, Robert M Donnino, Robert Bojar, Robert Chilton, Robert Guyton, Robert Henderson, Robert Kornberg, Robert Leber, Robert Mao, Robert Stenberg, Roberta P Santos, Roberto René Favaloro, Roberto Amati, Rodolfo G S D Lima, Rodrigo J Cerci, Rogerio Tumelero, Rohit Tandon, Roma Tewari, Romalisa Miranda-Peats, Ron Wald, Ronald A Mastouri, Ronald G Morford, Ronald G Schwartz, Ronald P Pedalino, Rongrong Hu, Ronnell A Hansen, Ronny A Cohen, Rory Hachamovitch, Rosa Homem, Rosa Sandonato, Rosane Laimer, Rosann Gans, Roxanne Yost, Roy Mathew, Rubén Baleón-Espinosa, Ruben Ramos, Rubine Gevorgyan, Rui Ferreira, Rui Jing, Ruth Pérez-Fernández, S K Dwivedi, S Ramakrishnan, Saadat Khan, Sabahat Bokhari, Sabu Thomas, Sadath Lubna, Sajeeda Parveen Khan, Sajeev Chakanalil Govindan, Saket Girotra, Saleem Kassam, Sallie Canada, Salvador Cruz-Flores, Samaa Mohamed, Samantha Ly, Sameh El Kaffas, Samia Massalha, Sampoornima Setty, Samuel Nwosu, Sandeep Seth, Sandeep Singh, Sander R Niehe, Sandra M Rivest, Sandra S Zier, Sandra Ahoud, Sandy Carr, Sanjay Ganapathi, Sanjay Shetty, Sanjeev Sharma, Santa Jimenez, Santhosh Satheesh, Santiago A Garcia, Sara Fernandez, Sara Karlsson, Sara Salkind, Sara Temiyasathit, Sarah Medina Rodriguez, Sarah Beaudry, Sarah Hadjih, Sarah Williams, Sarah Zahrani, Sarju Ralhan, Sasa Hinic, Sasko Kedev, Satinder Singh, Satoshi Yasuda, Satvic Cholenahally Manjunath, Sau Lee, Scott M Kaczkowski, Scott Kinlay, Sean W Hayes, Sebastian Sobczak, Senait Asier, Sergey A Sayganov, Seth I Sokol, Shaheen Pandie, Shaiful Azmi Yahaya, Shamir Mehta, Shao-Ping Nie, Sharad Chandra, Sharder Islam, Sharon Tai, Sheetal Rupesh Karwa, Sheri Ussery, Sheromani Bajaj, Sherron C Crook, Shigeyuki Nishimura, Shintaro Nakano, Shirin Heydari, Shiv Kumar Choudhary, Shivali Patel, Shobana Ganesan, Shruti Pandey, Shuyang Zhang, Shweta Hande, Siddharth Gadage, Sik-Yin V Tan, Silvia Zottis Poletti, Silvia Riera, Silvia Valbuena, Simon Walsh, Simona Maspoli, Simone Savaris, Si-Ting Feng, So Yang Cho, Solomon Yakubov, Songlin Zhu, Songtao Wang, Sonia Guerrero, Sonika Gupta, Sonja Salinger Martinovic, Sonya Brons, Sorin Brener, Sothinathan Gurunathan, Souheil Saba, Soundarya Nayak, Sowjanya Reddy, Srinivasa Potluri, Sriram Sudarshan, Srun Kuanprasert, Stacie Van Oosterhout, Stamatios Lerakis, Stanley E Cobos, Stefan C Bertog, Stefan M Simović, Stefan Weikl, Stefano Di Marco, Stefano Provasoli, Stephanie A Tirado, Stephanie C Boer, Stephanie M Lane, Stephanie Ferket, Stephanie Kelly, Stephanie Wasmiller, Stephen H McKellar, Stephen P Hoole, Stephen Fremes, Stephen Preston, Steve Leung, Steven A Fein, Steven J Lindsay, Steven P Sedlis, Steven Giovannone, Steven Michael, Steven Weitz, Stijn van Vugt, Subhash Banerjee, Sudhir Naik, Suellen Hosino, Sukie Desire, Sukit Yamwong, Suku T Thambar, Sulagna Mookherjee, Suman Singh, Sundeep Mishra, Sunil Kumar Verma, Supap Kulthawong, Supatchara Khwakhong, Surendra Naik, Suresh Babu, Surin Woragidpoonpol, Suryaprakash Narayanappa, Susan Derbyshire, Susan Gent, Susan Mathus, Susan Milbrandt, Susan Moore, Susan Regan, Susan Stinson, Susan Webber, Susana Silva, Susanna Stevens, Susanne Gruensfelder, Suthara Aramcharoen, Suvarna Kolhe, Suzana Tavares, Suzanne Arnold, Suzanne Welsh, Svetlana Apostolovic, Swapna Kunhunny, Ta-Chuan Hung, Taissa Zappernick, Tali Sharir, Talita Silva, Tamara Colaiácovo Soares, Tapan Umesh Pillay, Tarun K Mittal, Tatiana Trifonova, Tauane Bello Duarte, Tauqir Huk, Téodora Dutoiu, Terrance Chua, Terry Weyand, Thabitha Charles, Theodoros Kofidis, Theresa McCreary, Thierry Lefevre, Thippeekaa Arumairajah, Thitipong Tepsuwan, Thomas J Mulhearn, Thomas M Meyer, Thomas P Rocco, Thomas R Downes, Thomas Crain, Thomas Haldis, Thomas Mathew, Thomas Redick, Thounaojam Indira Devi, Thuraia Nageh, Tia Cauthren, Tiago Silva, Tiffany Little, Tijana Andric, Tina Harding, Titus Lau, Tiziana Formisano, Tiziano Moccetti, Tomasz Ciurus, Tomasz Mazurek, Tomasz Tarchalski, Toshiyuki Nagai, Tri Tran, Tricia Youn, Trish Tucker, Trudie Milner, Tuhina Bose, Tushar Kotecha, Udo Sechtem, Uma S Valeti, Umberto Cucchini, Umesh Badami, Upendra Kaul, V K Bahl, V S Narain, Valentina Casali, Valeria Godoy, Valerie Robesyn, Vamshi P Priya, Vandana Yadav, Vera McKinney, Veronica De Lenges, Veronica Tinnirello, Vicente Miro, Victor Navarro, Victoria Gumerova, Victoria Hernandez, Vidya Seeratan, Vijay Kumar, Vikentiy Y Kozulin, Viktoria Bulkley, Vilmar Veiga Jr, Vincent Setang, C P Vineeth, Virginai Pubull Nuñez, Virginia Fernández-Figares, Vitor Gomes, Viviana Gabriel, Viviane Dos Santos, Viviane Almeida, Vlad A Iliescu, Vladan Mudrenovic, Vladimir Dzavik, Vojislav L Giga, Walter Enrique Mogrovejo, Wan Xian Chan, Wanda C Marfori, Wanda Parker, Warangkana Mekara, Wassim Nona, Wayne Old, Wayne Pennachi, Weerachai Nawarawong, Wei Chen, Wei Su, Weibing Xing, Wei-Ren Lan, Wenda Crawford, Wendy L Stewart, Wendy Drewes, Wenhua Lin, William B Abernethy, William D Salerno, William F Fearon, William Vergoni, William Weintraub, Winnie C Sia, Wlodzimierz J Musial, Xacobe Flores-Ríos, Xavier Garcia-Moll Marimon, Xi Su, Xiang Ma, Xiangqiong Gu, Xiao Wang, Xiaomei Li, Xiaowei Yao, Xin Fu, Xin Su, Xin Zeng, Xinchun Yang, Xiuhong Li, Xuehua Fang, Xutong Wang, Yaming Geng, Yan Yan, Yanek Pépin-Dubois, Yanfu Wang, Yang Wang, Yanmeng Tian, Yaping Huang, Yechen Han, Yesenia Zambrano, Yi-Hsuan Yang, Ying Tung Sia, Yining Yang, Yitong Ma, Yolayfi Peralta, Yongjian Wu, Yu Kunwu, Yu Zhao, Yudong Peng, Yueh-Hung Lin, Yulan Zhao, Yumei Dong, Yunhai Zhao, Yutthaphan Wannasopha, Yvonne Taul, Zakir Sahul, Zalina Kudzoeva, Zbigniew Kalarus, Zeljko Z Markovic, Zhen Huang, Zheng Ji, Zhenyu Liu, Zhou Yue, Zhulin Zhang, Zhuxi Li, Zile Singh Meharwal, Ziliang Bai, Zixiang Yu, Zohra Huda, Zoltan Davidovits

Subjects
Male, Cardiac Catheterization, Computed Tomography Angiography, medicine.medical_treatment, Myocardial Ischemia, Coronary Disease, Coronary Artery Disease, Kaplan-Meier Estimate, 030204 cardiovascular system & hematology, Coronary Angiography, ISCHEMIA Research Group, law.invention, Angina, Coronary artery disease, 0302 clinical medicine, Randomized controlled trial, law, Cardiovascular Disease, Myocardial Revascularization, 030212 general & internal medicine, Coronary Artery Bypass, 11 Medical and Health Sciences, Cardiac catheterization, General Medicine, Middle Aged, humanities, Cardiovascular Diseases, Cardiology, Female, Human, medicine.medical_specialty, Ischemia, Article, 03 medical and health sciences, Geriatric cardiology, Percutaneous Coronary Intervention, General & Internal Medicine, Internal medicine, medicine, Humans, Angina, Unstable, Aged, business.industry, Coronary Artery Bypa, Percutaneous coronary intervention, Bayes Theorem, medicine.disease, Heart failure, Quality of Life, business
Abstract

BACKGROUND: Among patients with stable coronary disease and moderate or severe ischemia, whether clinical outcomes are better in those who receive an invasive intervention plus medical therapy than in those who receive medical therapy alone is uncertain. METHODS: We randomly assigned 5179 patients with moderate or severe ischemia to an initial invasive strategy (angiography and revascularization when feasible) and medical therapy or to an initial conservative strategy of medical therapy alone and angiography if medical therapy failed. The primary outcome was a composite of death from cardiovascular causes, myocardial infarction, or hospitalization for unstable angina, heart failure, or resuscitated cardiac arrest. A key secondary outcome was death from cardiovascular causes or myocardial infarction. RESULTS: Over a median of 3.2 years, 318 primary outcome events occurred in the invasive-strategy group and 352 occurred in the conservative-strategy group. At 6 months, the cumulative event rate was 5.3% in the invasive-strategy group and 3.4% in the conservative-strategy group (difference, 1.9 percentage points; 95% confidence interval [CI], 0.8 to 3.0); at 5 years, the cumulative event rate was 16.4% and 18.2%, respectively (difference, -1.8 percentage points; 95% CI, -4.7 to 1.0). Results were similar with respect to the key secondary outcome. The incidence of the primary outcome was sensitive to the definition of myocardial infarction; a secondary analysis yielded more procedural myocardial infarctions of uncertain clinical importance. There were 145 deaths in the invasive-strategy group and 144 deaths in the conservative-strategy group (hazard ratio, 1.05; 95% CI, 0.83 to 1.32). CONCLUSIONS: Among patients with stable coronary disease and moderate or severe ischemia, we did not find evidence that an initial invasive strategy, as compared with an initial conservative strategy, reduced the risk of ischemic cardiovascular events or death from any cause over a median of 3.2 years. The trial findings were sensitive to the definition of myocardial infarction that was used. (Funded by the National Heart, Lung, and Blood Institute and others; ISCHEMIA ClinicalTrials.gov number, NCT01471522.).

Published
2020
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49. The response of phytoplankton production to periodic upwelling and relaxation events at the Iberian shelf break: estimates by the 14C method and by satellite remote sensing

Author

Joint, Ian, Groom, Stephen B., Wollast, Roland, Chou, Lei, Tilstone, Gavin H., Figueiras, Francisco G., Loijens, Michèle, and Smyth, Timothy J.

Subjects
*PHYTOPLANKTON, *UPWELLING (Oceanography), *REMOTE sensing
Abstract

The primary productivity of the NW Iberian margin has been determined by a combination of 14C incorporation experiments on natural phytoplankton assemblages and satellite remote sensing with the ocean colour sensor, SeaWiFS. The approach to the field determination of phytoplankton production was Eulerian, involving measurements on a fixed grid of stations covering the region from 41°30′N to 43°00′N and 09°00′W to 10°30′W. Three different laboratories made primary production measurements over a 3-year period. Each group used variations of the 14C method—in situ incubations and two modelling approaches based on P–E parameter derivation. An intercalibration experiment showed acceptable agreement between the three estimates. Measurements by the three groups on eight cruises have been merged to provide estimates of regional productivity. However, the temporal coverage of the data was too limited to provide robust seasonal estimates since few experiments were done in the autumn and winter months.A second approach to the estimation of primary production utilised surface pigment concentrations derived from satellite remote sensing. Two models were used. Firstly, an empirical relationship was found between depth-integrated primary production and surface chlorophyll concentration, which explained 78% of the variance in the production estimates. The second approach used a semi-analytical model which incorporates irradiance and temperature as well as chlorophyll-derived parameters. Both models have been applied to SeaWiFS-derived, surface chlorophyll concentrations to estimate primary production during 1998, 1999 and 2000 for three regions—the shelf, the slope and the open ocean of the region of study. Using the semi-analytical model, the mean primary production for the 3 years is estimated to be 319 g C m−2 year−1 for the shelf, 280 g C m−2 year−1 for the slope and 217 g C m−2 year−1 for the adjacent open ocean. Interannual variation in production on the shelf ranged from 334 g C m−2 year−1 in 1998 to 301 g C m−2 year−1 in 2000. It is estimated that upwelling increased primary production, relative to that in the open ocean, by ∼50%. Satellite-derived estimates of the ratio of new production to primary production were 0.37, 0.28 and 0.40 for the shelf region during the upwelling seasons of 1998, 1999 and 2000. [Copyright &y& Elsevier]

Published
2002
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50. Influencia del cultivo de mejillón en la comunidad de plancton microbiano en la Ría de Vigo

Author

Froján, M., Gómez Figueiras, Francisco, González Castro, Carmen, Roson Porto, Gabriel, Castro, Carmen G., and Figueiras, F. G.

Subjects
2510.01 Oceanografía Biológica, 2510.92 Acuicultura Marina
Abstract

213 páginas, Entre la enorme diversidad de organismos que habitan los ambientes marinos, el plancton microbiano destaca por su profunda influencia en los ciclos biogeoquímicos del océano y por su papel trascendental en la transferencia de materia y energía a través de la red trófica pelágica (Sherr & Sherr 2000). En particular, la estructura de tamaños y composición de la comunidad de plancton microbiano determina la ruta de transferencia de carbono a través del ecosistema. De esta forma, el carbono fijado por los productores primarios puede ser reciclado en las capas superficiales, transferido a niveles tróficos superiores o exportado verticalmente al océano profundo (Legendre & Le Fèvre 1989). A pesar de su importancia, hasta la fecha no existe una caracterización exhaustiva de la comunidad de plancton microbiano en las Rías Baixas, en cuanto estructura de tamaños y modo de nutrición y en función de las condiciones ambientales a escala estacional. Siendo importante esta caracterización en sí misma, lo es todavía más teniendo en cuenta el cultivo intensivo de mejillón existente en la región. El mejillón Mytilus galloprovincialis (Lamarck 1819) se cultiva en Galicia desde hace 70 años. La primera batea se instaló en la Ría de Arosa en el año 1946 y desde entonces, este método de cultivo en suspensión se ha expandido rápidamente por las Rías Gallegas. En la actualidad, hay un total de 3.337 bateas, 478 de ellas en la Ría Vigo, y la producción de mejillón en Galicia se ha estabilizado en torno a las 250.000 toneladas anuales, convirtiéndose en la región más productiva de Europa y una de las más importantes del mundo (Figueiras et al. 2002). De este modo, el sector mejillonero representa un importante motor de desarrollo social y económico para los municipios costeros en los que se desenvuelve esta actividad, generando 9.000 empleos directos y alrededor de 20.000 indirectos (Labarta 2004)., Estudios recientes en las Rías Gallegas han mostrado que el cultivo de mejillón altera significativamente la cadena trófica del ecosistema (Tenore & González 1975, Cabanas et al. 1979, Tenore et al. 1982, Petersen et al. 2008, Maar et al. 2008), a la vez que incrementa las tasas de sedimentación bajo las bateas (Cabanas et al. 1979, Tenore et al. 1982, Alonso-Pérez et al. 2010, Zúñiga et al. 2014). Sin embargo, por el momento se desconoce qué impacto produce el cultivo del mejillón en el conjunto de la comunidad de plancton microbiano. En este contexto, la presente tesis tiene por objeto analizar la influencia del cultivo del mejillón en la estructura de tamaños y composición de la comunidad planctónica microbiana, y los consiguientes efectos sobre la producción primaria, el balance metabólico y la exportación vertical de partículas biogénicas en la Ría de Vigo. La finalidad de esta investigación es aportar nueva información del papel que desempeña el cultivo de mejillón en esta región de afloramiento costero, cara a favorecer la sostenibilidad del ecosistema., A continuación, se formulan los objetivos específicos de esta tesis: 1. Evaluar el efecto de la calidad del contenido orgánico del seston en el comportamiento alimentario de Mytilus galloprovincialis Lmk (Capítulo 2). 2. Analizar el impacto del cultivo del mejillón en la biogeoquímica de la columna de agua en la Ría de Vigo (Capítulo 2). 3. Caracterizar la estructura de tamaños y composición de la comunidad de plancton microbiano en la Ría de Vigo en relación a las condiciones hidrográficas registradas durante 4 periodos estacionales: otoño, invierno, primavera y verano (Capítulo 3). 4. Analizar el impacto del cultivo de mejillón en la estructura y composición de la comunidad de plancton microbiano en la Ría de Vigo en cada periodo estacional (Capítulo 3). 5. Evaluar en qué medida el cultivo de mejillón puede alterar la distribución de tamaños de la producción y modificar el balance metabólico de la Ría de Vigo (Capítulo 4). 6. Evaluar la influencia del cultivo de mejillón en la sedimentación de fitoplancton en la Ría de Vigo (Capítulo 5)., Los trabajos que se recogen en esta memoria fueron financiados por el proyecto RAFTING: ‘Impact of mussel raft culture on the benthic-pelagic coupling in a Galician Ría’ financiado por el Ministerio de Ciencia e Innovación MICINN (CTM2007-61983/MAR, CTM2007-30624-E/MAR).

Published
2016

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