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1. Serious Games and Gamification: Health Care Workers Experience, Attitudes, and Knowledge.

Author

Katonai, Zoltan, Gupta, Rahul, Heuss, Sabina, Fehr, Thomas, Ebneter, Mark, Maier, Thomas, Meier, Thomas, Bux, Donald, Thackaberry, Jessica, and Schneeberger, Andres

Subjects
Gamification, Medical education, Postgraduate education, Serious games, Humans, Gamification, Pandemics, Video Games, COVID-19, Health Personnel
Abstract

OBJECTIVE: With the rapid advancement of digital technology due to COVID-19, the health care field is embracing the use of digital technologies for learning, which presents an opportunity for teaching methods such as serious games to be developed and improved. Technology offers more options for these educational approaches. The goal of this study was to assess health care workers experiences, attitudes, and knowledge regarding serious games in training. METHODS: The convenience sample consisted of 223 participants from the specialties of internal medicine and psychiatry who responded to questions regarding sociodemographic data, experience, attitudes, and knowledge regarding serious games. This study used an ordinal regression model to analyze the relationship between knowledge, attitudes, and experiences and the idea or wish to implement serious games. RESULTS: The majority of healthcare workers were not familiar with serious games or gamification. The results show gender and age differences regarding familiarity and willingness to use serious games. With increasing age, the respondents preferred conventional and traditional learning methods to playful teaching elements; younger generations were significantly more motivated than older generations when envisioning using elements of serious games in the future. CONCLUSIONS: The COVID-19 pandemic has encouraged the use of new technologies and digitalization. This study describes positive attitudes toward serious games, mainly in younger people working in health care. Serious games present an opportunity to develop new approaches for postgraduate medical teachings and continuing medical education.

Published
2023

2. Surgical site infections after kidney transplantation are independently associated with graft loss

Author

Amico, Patrizia, Aubert, John-David, Banz, Vanessa, Beckmann, Sonja, Beldi, Guido, Berger, Christoph, Berishvili, Ekaterine, Berzigotti, Annalisa, Binet, Isabelle, Bochud, Pierre-Yves, Branca, Sanda, Bucher, Heiner, Catana, Emmanuelle, Cairoli, Anne, Chalandon, Yves, De Geest, Sabina, De Rougemont, Olivier, De Seigneux, Sophie, Dickenmann, Michael, Dreifuss, Joëlle Lynn, Duchosal, Michel, Fehr, Thomas, Ferrari-Lacraz, Sylvie, Garzoni, Christian, Golshayan, Déla, Goossens, Nicolas, Haidar, Fadi, Halter, Jörg, Heim, Dominik, Hess, Christoph, Hillinger, Sven, Hirsch, Hans H., Hirt, Patricia, Hoessly, Linard, Hofbauer, Günther, Huynh-Do, Uyen, Immer, Franz, Koller, Michael, Laesser, Bettina, Lamoth, Frédéric, Lehmann, Roger, Leichtle, Alexander, Manuel, Oriol, Marti, Hans-Peter, Martinelli, Michele, McLin, Valérie, Mellac, Katell, Merçay, Aurélia, Mettler, Karin, Mueller, Nicolas J., Müller-Arndt, Ulrike, Müllhaupt, Beat, Nägeli, Mirjam, Oldani, Graziano, Pascual, Manuel, Passweg, Jakob, Pazeller, Rosemarie, Posfay-Barbe, Klara, Rick, Juliane, Rosselet, Anne, Rossi, Simona, Rothlin, Silvia, Ruschitzka, Frank, Schachtner, Thomas, Schaub, Stefan, Scherrer, Alexandra, Schnyder, Aurelia, Schuurmans, Macé, Schwab, Simon, Sengstag, Thierry, Simonetta, Federico, Stampf, Susanne, Steiger, Jürg, Stirnimann, Guido, Stürzinger, Ueli, Van Delden, Christian, Venetz, Jean-Pierre, Villard, Jean, Vionnet, Julien, Wick, Madeleine, Wilhelm, Markus, Yerly, Patrick, Schreiber, Peter W., Hoessly, Linard D., Boggian, Katia, Neofytos, Dionysios, van Delden, Christian, Egli, Adrian, Hirzel, Cédric, Schmied, Bruno, Guerke, Lorenz, Matter, Maurice, de Rougemont, Olivier, Bonani, Marco, Sidler, Daniel, and Kuster, Stefan P.

Published
2024
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3. BK polyomavirus serotype-specific antibody responses in blood donors and kidney transplant recipients with and without new-onset BK polyomavirus-DNAemia: A Swiss Transplant Cohort Study

Author

Amico, Patrizia, Bachofner, Adrian, Banz, Vanessa, Beckmann, Sonja, Beldi, Guido, Berger, Christoph, Berishvili, Ekaterine, Berzigotti, Annalisa, Binet, Françoise-Isabelle, Bochud, Pierre-Yves, Borner, Petra, Branca, Sanda, Cairoli, Anne, Catana, Emmanuelle, Chalandon, Yves, Compagnon, Philippe, De Geest, Sabina, De Seigneux, Sophie, Dickenmann, Michael, Dreifuss, Joëlle Lynn, Duchosal, Michel, Fehr, Thomas, Ferrari-Lacraz, Sylvie, Flammer, Andreas, Frossard, Jaromil, Golshayan, Dela, Goossens, Nicolas, Haidar, Fadi, Halter, Jürg, Hess, Christoph, Hillinger, Sven, Hirsch, Hans H., Hirt, Patricia, Hoessly, Linard, Hofbauer, Günther, Huynh-Do, Uyen, Immer, Franz, Khanna, Nina, Koller, Michael, Kremer, Andreas, Krueger, Thorsten, Kuhn, Christian, Laesser, Bettina, Lamoth, Frédéric, Lehmann, Roger, Leichtle, Alexander, L'Huillier, Arnaud, Manuel, Oriol, Marti, Hans-Peter, Martinelli, Michele, McLin, Valérie, Mellac, Katell, Merçay, Aurélia, Mettler, Karin, Müller, Nicolas, Müller, Jelena, Müller-Arndt, Ulrike, Nägeli, Mirjam, Neofytos, Dionysios, Nilsson, Jakob, Pascual, Manuel, Pazeller, Rosmarie, Reineke, David, Rick, Juliane, Rössler, Fabian, Rothlin, Silvia, Schachtner, Thomas, Schaub, Stefan, Schneidawind, Dominik, Schuurmans, Macé, Schwab, Simon, Sengstag, Thierry, Sidler, Daniel, Simonetta, Federico, Steiger, Jürg, Stirnimann, Guido, Stürzinger, Ueli, Van Delden, Christian, Venetz, Jean-Pierre, Villard, Jean, Vionnet, Julien, Wehmeier, Caroline, Wilhelm, Markus, Yerly, Patrick, Hillenbrand, Caroline A., Bani, Dorssa Akbari, Follonier, Océane, Kaur, Amandeep, Weissbach, Fabian H., Wernli, Marion, Wilhelm, Maud, Leuzinger, Karoline, Binet, Isabelle, Hirzel, Cédric, and Mueller, Nicolas J.

Published
2024
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4. Reintegration Into the Workforce After Kidney Transplantation Based on Urbanization Status in Switzerland

Author

Amico, Patrizia, Bachofner, Adrian, Banz, Vanessa, Beckmann, Sonja, Beldi, Guido, Berger, Christoph, Berishvili, Ekaterine, Berzigotti, Annalisa, Bochud, Pierre-Yves, Branca, Sanda, Bucher, Heiner, Cairoli, Anne, Catana, Emmanuelle, Chalandon, Yves, De Geest, Sabina, De Seigneux, Sophie, Dickenmann, Michael, Dreifuss, Joëlle Lynn, Duchosal, Michel, Fehr, Thomas, Ferrari-Lacraz, Sylvie, Frossard, Jaromil, Garzoni, Christian, Golshayan, Déla, Goossens, Nicolas, Haidar, Fadi, Halter, Jörg, Heim, Dominik, Hess, Christoph, Hillinger, Sven, Hirsch, Hans, Hirt, Patricia, Hoessly, Linard, Hofbauer, Günther, Huynh-Do, Uyen, Immer, Franz, Koller, Michael, Kremer, Andreas, Krueger, Thorsten, Kuhn, Christian, Laesser, Bettina, Lamoth, Frédéric, Lehmann, Roger, Leichtle, Alexander, Manuel, Oriol, Marti, Hans-Peter, Martinelli, Michele, McLin, Valérie, Mellac, Katell, Merçay, Aurélia, Mettler, Karin, Müller, Nicolas, Müller-Arndt, Ulrike, Müllhaupt, Beat, Nägeli, Mirjam, Oldani, Graziano, Pascual, Manuel, Passweg, Jakob, Pazeller, Rosemarie, Posfay-Barbe, Klara, Reineke, David, Rick, Juliane, Rosselet, Anne, Rossi, Simona, Rössler, Rothlin, Silvia, Ruschitzka, Frank, Schachtner, Thomas, Schaub, Stefan, Scherrer, Alexandra, Schneidawind, Dominik, Schnyder, Aurelia, Schuurmans, Macé, Schwab, Simon, Sengstag, Thierry, Simonetta, Federico, Steiger, Jürg, Stirniman, Guido, Stürzinger, Ueli, Van Delden, Christian, Venetz, Jean-Pierre, Villard, Jean, Vionnet, Julien, Wick, Madeleine, Wilhlem, Markus, Yerly, Patrick, Bocchi, Federica, Müller, Selina, Binet, Isabelle, Golshayan, Dela, Müller, Thomas, Sidler, Daniel, and Storni, Federico

Published
2024
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5. Outcome of Patients Transplanted for C3 Glomerulopathy and Primary Immune Complex-Mediated Membranoproliferative Glomerulonephritis

Author

Amico, Patrizia, Aubert, John-David, Banz, Vanessa, Beckmann, Sonia, Beldi, Guido, Berger, Christoph, Berishvili, Ekaterine, Binet, Isabelle, Bochud, Pierre-Yves, Branca, Sanda, Bucher, Heiner, Catana, Emmanuelle, Chalandon, Yves, De Geest, Sabina, De Seigneux Michael Dickenmann, Sophie, Dreifuss, Joëlle Lynn, Duchosal, Michel, Fehr, Thomas, Ferrari-Lacraz, Sylvie, Garzoni, Christian, Gaudet, Christophe, Golshayan, Déla, Goossens, Nicolas, Halter, Jörg, Heim, Dominik, Hess, Christoph, Hillinger, Sven, Hirsch, Hans H., Hirt, Patricia, Hofbauer, Günther, Huynh-Do, Uyen, Immer, Franz, Koller, Michael, Laager, Mirjam, Laesser, Bettina, Lamoth, Frédéric, Lehmann, Roger, Leichtle, Alexander, Manuel, Oriol, Marti, Hans-Peter, Martinelli, Michele, McLin, Valérie, Mellac, Katell, Mercay, Aurelia, Mettler, Karin, Mueller, Nicolas J., Müller, Antonia, Müller-Arndt, Ulrike, Müllhaupt, Beat, Nägeli, Mirjam, Oldani, Graziano, Pascual, Manuel, Passweg, Jakob, Posfay-Barbe, Klara, Rick, Juliane, Rosselet, Anne, Rossi, Simona, Rothlin, Silvia, Ruschitzka, Frank, Schachtner, Thomas, Schanz, Urs, Schaub, Stefan, Schwab, Simon, Schnyder, Aurelia, Schuurmans, Macé, Sengstag, Thierry, Simonetta, Federico, Steiger, Jürg, Stirniman, Guido, Stürzinger, Ueli, Van Delden, Christian, Venetz, Jean-Pierre, Villard, Jean, Vionnet, Julien, Wick, Madeleine, Wilhlem, Markus, Yerly, Patrick, Halfon, Matthieu, Taffé, Patrick, Bucher, Christian, Haidar, Fadi, Huynh-do, Uyen, Mani, Laila-Yasmin, Wehmeier, Caroline, Fakhouri, Fadi, and Golshayan, Dela

Published
2024
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7. The MELD upgrade exception: a successful strategy to optimize access to liver transplantation for patients with high waiting list mortality

Author

Amico, Patrizia, Axel, Andres, Aubert, John-David, Banz, Vanessa, Sonja, Beckmann, Beldi, Guido, Benden, Christian, Berger, Christoph, Binet, Isabelle, Bochud, Pierre-Yves, Branca, Sanda, Bucher, Heiner, Carrel, Thierry, Catana, Emmanuelle, Chalandon, Yves, de Geest, Sabina, de Rougemont, Olivier, Dickenmann, Michael, Dreifuss, Joëlle L., Duchosal, Michel, Fehr, Thomas, Ferrari-Lacraz, Sylvie, Garzoni, Christian, Soccal, Paola G., Gaudet, Christophe, Giostra, Emiliano, Golshayan, Déla, Hadaya, Karine, Halter, Jörg, Hauri, Dimitri, Heim, Dominik, Hess, Christoph, Hillinger, Sven, Hirsch, Hans, Hirt, Patricia, Hofbauer, Günther, Huynh-Do, Uyen, Immer, Franz, Koller, Michael, Laesser, Bettina, Lang, Brian, Lehmann, Roger, Leichtle, Alexander, Lovis, Christian, Manuel, Oriol, Marti, Hans-Peter, Martin, Pierre Y., Martinelli, Michele, Mellac, Katell, Merçay, Aurélia, Mettler, Karin, Meylan, Pascal, Mueller, Nicolas, Müller, Antonia, Müller, Thomas, Müller-Arndt, Ulrike, Müllhaupt, Beat, Nägeli, Mirjam, Pascual, Manuel, Posfay-Barbe, Klara, Rick, Juliane, Rosselet, Anne, Rossi, Simona, Rothlin, Silvia, Ruschitzka, Frank, Schanz, Urs, Schaub, Stefan, Schnyder, Aurelia, Schuurmans, Macé, Simonetta, Federico, Staufer, Katharina, Stampf, Susanne, Steiger, Jürg, Stirniman, Guido, Stürzinger, Ueli, Toso, Christian, Van Delden, Christian, Venetz, Jean-Pierre, Villard, Jean, Vionnet, Julien, Wick, Madeleine, Wilhlem, Markus, Yerly, Patrick, Dirchwolf, Melisa, Becchetti, Chiara, Gschwend, Sarah G., Dutkowski, Philipp, Beyeler, Franziska, Schropp, Jonas, and Dufour, Jean-François

Published
2022
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10. Historic characteristics and mortality of patients in the Swiss Amyloidosis Registry

Author

Brouwers, Sofie; https://orcid.org/0000-0002-7081-4881, Heimgartner, Raphael, Laptseva, Natallia, Aguzzi, Adriano; https://orcid.org/0000-0002-0344-6708, Ehl, Niklas F, Fehr, Thomas; https://orcid.org/0000-0003-1668-1800, Hitz, Felicitas; https://orcid.org/0000-0001-5653-5117, Jung, Hans H, Kälin, Joel, Manz, Markus G; https://orcid.org/0000-0002-4676-7931, Müllhaupt, Beat; https://orcid.org/0000-0002-9020-8192, Ruschitzka, Frank; https://orcid.org/0000-0001-5972-0596, Seeger, Harald; https://orcid.org/0000-0003-1552-7983, Stussi, Georg; https://orcid.org/0000-0002-1667-0637, Zweier, Markus; https://orcid.org/0000-0001-8290-0413, Flammer, Andreas J; https://orcid.org/0000-0002-1373-0630, Gerber, Bernhard, Schwotzer, Rahel, Brouwers, Sofie; https://orcid.org/0000-0002-7081-4881, Heimgartner, Raphael, Laptseva, Natallia, Aguzzi, Adriano; https://orcid.org/0000-0002-0344-6708, Ehl, Niklas F, Fehr, Thomas; https://orcid.org/0000-0003-1668-1800, Hitz, Felicitas; https://orcid.org/0000-0001-5653-5117, Jung, Hans H, Kälin, Joel, Manz, Markus G; https://orcid.org/0000-0002-4676-7931, Müllhaupt, Beat; https://orcid.org/0000-0002-9020-8192, Ruschitzka, Frank; https://orcid.org/0000-0001-5972-0596, Seeger, Harald; https://orcid.org/0000-0003-1552-7983, Stussi, Georg; https://orcid.org/0000-0002-1667-0637, Zweier, Markus; https://orcid.org/0000-0001-8290-0413, Flammer, Andreas J; https://orcid.org/0000-0002-1373-0630, Gerber, Bernhard, and Schwotzer, Rahel

Abstract

AIMS OF THE STUDY: Systemic amyloidoses are rare protein-folding diseases with heterogeneous, often nonspecific clinical presentations. To better understand systemic amyloidoses and to apply state-of-the-art diagnostic pathways and treatment, the interdisciplinary Amyloidosis Network was founded in 2013 at University Hospital Zurich. In this respect, a registry was implemented to study the characteristics and life expectancy of patients with amyloidosis within the area covered by the network. Patient data were collected retrospectively for the period 2005–2014 and prospectively from 2015 onwards. METHODS: Patients aged 18 years or older diagnosed with any subtype of systemic amyloidosis were eligible for inclusion if they were treated in one of the four referring centres (Zurich, Chur, St Gallen, Bellinzona). Baseline data were captured at the time of diagnosis. Follow-up data were assessed half-yearly for the first two years, then annually. RESULTS: Between January 2005 and March 2020, 247 patients were screened, and 155 patients with confirmed systemic amyloidosis were included in the present analysis. The most common amyloidosis type was light-chain (49.7%, n = 77), followed by transthyretin amyloidosis (40%, n = 62) and amyloid A amyloidosis (5.2%, n = 8). Most patients (61.9%, n = 96) presented with multiorgan involvement. Nevertheless, single organ involvement was seen in all types of amyloidosis, most commonly in amyloid A amyloidosis (75%, n = 6). The median observation time of the surviving patients was calculated by the reverse Kaplan-Meier method and was 3.29 years (95% confidence interval [CI] 2.33–4.87); it was 4.87 years (95% CI 3.14–7.22) in light-chain amyloidosis patients and 1.85 years (95% CI 1.48–3.66) in transthyretin amyloidosis patients, respectively. The 1-, 3- and 5-year survival rates were 87.0% (95% CI 79.4–95.3%), 68.5% (95% CI 57.4–81.7%) and 66.0% (95% CI 54.6–79.9%) respectively for light-chain amyloidosis patients and 91.2% (95% CI 83

Published
2024

11. Clinical and genetic spectra of autosomal dominant tubulointerstitial kidney disease due to mutations in UMOD and MUC1

Author

Olinger, Eric, Hofmann, Patrick, Kidd, Kendrah, Dufour, Inès, Belge, Hendrica, Schaeffer, Céline, Kipp, Anne, Bonny, Olivier, Deltas, Constantinos, Demoulin, Nathalie, Fehr, Thomas, Fuster, Daniel G., Gale, Daniel P., Goffin, Eric, Hodaňová, Kateřina, Huynh-Do, Uyen, Kistler, Andreas, Morelle, Johann, Papagregoriou, Gregory, Pirson, Yves, Sandford, Richard, Sayer, John A., Torra, Roser, Venzin, Christina, Venzin, Reto, Vogt, Bruno, Živná, Martina, Greka, Anna, Dahan, Karin, Rampoldi, Luca, Kmoch, Stanislav, Bleyer, Anthony J., Sr., and Devuyst, Olivier

Published
2020
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13. Historic characteristics and mortality of patients in the Swiss Amyloidosis Registry

Author

Brouwers, Sofie, primary, Heimgartner, Raphael, additional, Laptseva, Natallia, additional, Aguzzi, Adriano, additional, Ehl, Niklas F., additional, Fehr, Thomas, additional, Hitz, Felicitas, additional, Jung, Hans H., additional, Kälin, Joel, additional, Manz, Markus G., additional, Müllhaupt, Beat, additional, Ruschitzka, Frank, additional, Seeger, Harald, additional, Stussi, Georg, additional, Zweier, Markus, additional, Flammer, Andreas J., additional, Gerber, Bernhard, additional, and Schwotzer, Rahel, additional

Published
2024
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19. Selective Bcl-2 inhibition promotes hematopoietic chimerism and allograft tolerance without myelosuppression in nonhuman primates

Author

Sasaki, Hajime, primary, Hirose, Takayuki, additional, Oura, Tetsu, additional, Otsuka, Ryo, additional, Rosales, Ivy, additional, Ma, David, additional, Lassiter, Grace, additional, Karadagi, Ahmad, additional, Tomosugi, Toshihide, additional, Dehnadi, Abbas, additional, Matsunami, Masatoshi, additional, Raju Paul, Susan, additional, Reeves, Patrick M., additional, Hanekamp, Isabel, additional, Schwartz, Samuel, additional, Colvin, Robert B., additional, Lee, Hang, additional, Spitzer, Thomas R., additional, Cosimi, A. Benedict, additional, Cippà, Pietro E., additional, Fehr, Thomas, additional, and Kawai, Tatsuo, additional

Published
2023
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20. Clinical prediction model for prognosis in kidney transplant recipients (KIDMO): study protocol

Author

Schwab, Simon; https://orcid.org/0000-0002-1588-2689, Sidler, Daniel, Haidar, Fadi, Kuhn, Christian, Schaub, Stefan, Koller, Michael, Mellac, Katell, Stürzinger, Ueli, Tischhauser, Bruno, Binet, Isabelle, Golshayan, Déla, Müller, Thomas, Elmer, Andreas, Franscini, Nicola, Krügel, Nathalie, Fehr, Thomas, Immer, Franz, Swisstransplant Kidney Working Group (STAN), Swiss Transplant Cohort Study, Schwab, Simon; https://orcid.org/0000-0002-1588-2689, Sidler, Daniel, Haidar, Fadi, Kuhn, Christian, Schaub, Stefan, Koller, Michael, Mellac, Katell, Stürzinger, Ueli, Tischhauser, Bruno, Binet, Isabelle, Golshayan, Déla, Müller, Thomas, Elmer, Andreas, Franscini, Nicola, Krügel, Nathalie, Fehr, Thomas, Immer, Franz, Swisstransplant Kidney Working Group (STAN), and Swiss Transplant Cohort Study

Abstract

Background: Many potential prognostic factors for predicting kidney transplantation outcomes have been identified. However, in Switzerland, no widely accepted prognostic model or risk score for transplantation outcomes is being routinely used in clinical practice yet. We aim to develop three prediction models for the prognosis of graft survival, quality of life, and graft function following transplantation in Switzerland. Methods: The clinical kidney prediction models (KIDMO) are developed with data from a national multi-center cohort study (Swiss Transplant Cohort Study; STCS) and the Swiss Organ Allocation System (SOAS). The primary outcome is the kidney graft survival (with death of recipient as competing risk); the secondary outcomes are the quality of life (patient-reported health status) at 12 months and estimated glomerular filtration rate (eGFR) slope. Organ donor, transplantation, and recipient-related clinical information will be used as predictors at the time of organ allocation. We will use a Fine & Gray subdistribution model and linear mixed-effects models for the primary and the two secondary outcomes, respectively. Model optimism, calibration, discrimination, and heterogeneity between transplant centres will be assessed using bootstrapping, internal-external cross-validation, and methods from meta-analysis. Discussion: Thorough evaluation of the existing risk scores for the kidney graft survival or patient-reported outcomes has been lacking in the Swiss transplant setting. In order to be useful in clinical practice, a prognostic score needs to be valid, reliable, clinically relevant, and preferably integrated into the decision-making process to improve long-term patient outcomes and support informed decisions for clinicians and their patients. The state-of-the-art methodology by taking into account competing risks and variable selection using expert knowledge is applied to data from a nationwide prospective multi-center cohort study. Ideally, healthca

Published
2023

21. Mammalian Target of Rapamycin Inhibitors and Kidney Function After Thoracic Transplantation: A Systematic Review and Recommendations for Management of Lung Transplant Recipients

Author

Schmucki, Katja, Hofmann, Patrick; https://orcid.org/0000-0002-4586-641X, Fehr, Thomas; https://orcid.org/0000-0003-1668-1800, Inci, Ilhan; https://orcid.org/0000-0003-3937-7705, Kohler, Malcolm; https://orcid.org/0000-0003-1800-8003, Schuurmans, Macé M; https://orcid.org/0000-0001-5404-7566, Schmucki, Katja, Hofmann, Patrick; https://orcid.org/0000-0002-4586-641X, Fehr, Thomas; https://orcid.org/0000-0003-1668-1800, Inci, Ilhan; https://orcid.org/0000-0003-3937-7705, Kohler, Malcolm; https://orcid.org/0000-0003-1800-8003, and Schuurmans, Macé M; https://orcid.org/0000-0001-5404-7566

Abstract

Background: Chronic kidney disease (CKD) after lung transplantation is common and limits the survival of transplant recipients. The calcineurin inhibitors (CNI), cyclosporine A, and tacrolimus being the cornerstone of immunosuppression are key mediators of nephrotoxicity. The mammalian target of rapamycin (mTOR) inhibitors, sirolimus and everolimus, are increasingly used in combination with reduced CNI dosage after lung transplantation. Methods: This systematic review examined the efficacy and safety of mTOR inhibitors after lung transplantation and explored their effect on kidney function. Results: mTOR inhibitors are often introduced to preserve kidney function. Several clinical trials have demonstrated improved kidney function and efficacy of mTOR inhibitors. The potential for kidney function improvement and preservation increases with early initiation of mTOR inhibitors and low target levels for both mTOR inhibitors and CNI. No defined stage of CKD for mTOR inhibitor initiation exists, nor does severe CKD preclude the improvement of kidney function under mTOR inhibitors. Baseline proteinuria may negatively predict the preservation and improvement of kidney function. Discontinuation rates of mTOR inhibitors due to adverse effects increase with higher target levels. Conclusions: More evidence is needed to define the optimal immunosuppressive regimen incorporating mTOR inhibitors after lung transplantation. Not only the indication criteria for the introduction of mTOR inhibitors are needed, but also the best timing, target levels, and possibly discontinuation criteria must be defined more clearly. Current evidence supports the notion of nephroprotective potential under certain conditions.

Published
2023

25. Clinical prediction model for prognosis in kidney transplant recipients (KIDMO)

Author

Schwab, Simon, Sidler, Daniel, Haidar, Fadi, Kuhn, Christian, Schaub, Stefan, Koller, Michael, Mellac, Katell, Stürzinger, Ueli, Tischhauser, Bruno, Binet, Isabelle, Golshayan, Déla, Müller, Thomas, Elmer, Andreas, Franscini, Nicola, Krügel, Nathalie, Fehr, Thomas, and Immer, Franz

Subjects
glomerular filtration rate, quality of life, Prediction model, Medicine and Health Sciences, graft survival, kidney transplantation, prognostic model, risk calculator, prognosis, risk score
Abstract

Background: Many potential prognostic factors for predicting kidney transplantation outcomes have been identified. However, in Switzerland no widely accepted prognostic model or risk score for transplantation outcomes is being routinely used in clinical practice yet. We aim to develop three prediction models for the prognosis of graft survival, quality of life and graft function following transplantation in Switzerland. Methods: The clinical prediction models are developed with data from a national multi-centre cohort study (Swiss Transplant Cohort Study; STCS) and the Swiss Organ Allocation System (SOAS). The primary outcome is kidney graft survival (censored for death of recipient); the secondary outcomes are quality of life (patient-reported health status) at 12-months and estimated glomerular filtration rate (eGFR) slope. Organ donor, transplantation, and recipient-related clinical information will be used as predictors at the time of organ allocation. We will use a Cox model and linear mixed-effects models for the primary and the two secondary out-comes, respectively. Model optimism, calibration, discrimination and heterogeneity between transplant centres will be assessed using bootstrapping, internal-external cross-validation and methods from meta-analysis. Discussion: Thorough evaluation of existing risk scores for kidney graft survival or patient-reported outcomes has been lacking in the Swiss transplant setting. In order to be useful in clinical practice, a prognostic score need to be valid, reliable, clinically relevant and, preferably integrated into the decision-making process to improve long-term patient outcomes and support informed decisions for clinicians and their patients. State-of-the-art methodology and best practice in prediction modelling are applied to data from a nationwide prospective multi-centre cohort study. Ideally, healthcare providers together with patients can predetermine the risk they are willing to accept from a deceased-donor kidney, with graft survival, quality-of-life and graft function estimates available for their consideration. Keywords: Prediction model, prognostic model, prognosis, risk calculator, risk score, kidney transplantation, graft survival, quality of life, glomerular filtration rate

Published
2022
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32. Evolution of body weight parameters up to 3 years after solid organ transplantation: The prospective Swiss Transplant Cohort Study

Author

Beckmann, Sonja, Nikolic, Nataša, Denhaerynck, Kris, Binet, Isabelle, Koller, Michael, Boely, Elsa, De Geest, Sabina, Berben, Lut, Burkhalter, Hanna, Claes, Veerle, Helmy, Remon, Kirsch, Monika, Leppla, Lynn, Mauthner, Oliver, Struker, Marian, Boehler, Annette, Gerull, Sabine, Huynh‐Do, Uyen, Catana, Emmanuelle, Simcox, Amira, Seiler, Annina, Klaghofer, Richard, Künzler‐Heule, Patrizia, Achermann, Rita, Amico, Patrizia, Aubert, John‐David, Banz, Vanessa, Beldi, Guido, Benden, Christian, Berger, Christoph, Bochud, Pierre‐Yves, Bucher, Heiner, Bühler, Leo, Carell, Thierry, Chalandon, Yves, de Rougemont, Olivier, Dickenmann, Michael, Duchosal, Michel, Elkrief, Laure, Fehr, Thomas, Ferrari‐Lacraz, Sylvie, Garzoni, Christian, Soccal, Paola Gasche, Gaudet, Christophe, Giostra, Emiliano, Golshayan, Déla, Hadaya, Karine, Halter, Jörg, Heim, Dominik, Hess, Christoph, Hillinger, Sven, Hirsch, Hans H., Hofbauer, Günther, Immer, Franz, Laesser, Bettina, Lehmann, Roger, Lovis, Christian, Manuel, Oriol, Marti, Hans‐Peter, Martin, Pierre Yves, Meylan, Pascal, Mohacsi, Paul, Morel, Philippe, Mueller, Ulrike, Mueller, Nicolas J, Mueller‐McKenna, Helen, Müller, Antonia, Müller, Thomas, Müllhaupt, Beat, Nadal, David, Pascual, Manuel, Passweg, Jakob, Rick, Juliane, Roosnek, Eddy, Rosselet, Anne, Rothlin, Silvia, Ruschitzka, Frank, Schanz, Urs, Schaub, Stefan, Schnyder, Aurelia, Seiler, Christian, Stampf, Susanne, Steiger, Jürg, Stirnimann, Guido, Toso, Christian, Van Delden, Christian, Venetz, Jean‐Pierre, Villard, Jean, Wick, Madeleine, Wilhelm, Markus, and Yerly, Patrick

Published
2017
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35. The MELD upgrade exception: a successful strategy to optimize access to liver transplantation for patients with high waiting list mortality

Author

Dirchwolf, Melisa, primary, Becchetti, Chiara, additional, Gschwend, Sarah G., additional, Toso, Christian, additional, Dutkowski, Philipp, additional, Immer, Franz, additional, Beyeler, Franziska, additional, Rossi, Simona, additional, Schropp, Jonas, additional, Dufour, Jean-François, additional, Banz, Vanessa, additional, Amico, Patrizia, additional, Axel, Andres, additional, Aubert, John-David, additional, Sonja, Beckmann, additional, Beldi, Guido, additional, Benden, Christian, additional, Berger, Christoph, additional, Binet, Isabelle, additional, Bochud, Pierre-Yves, additional, Branca, Sanda, additional, Bucher, Heiner, additional, Carrel, Thierry, additional, Catana, Emmanuelle, additional, Chalandon, Yves, additional, de Geest, Sabina, additional, de Rougemont, Olivier, additional, Dickenmann, Michael, additional, Dreifuss, Joëlle L., additional, Duchosal, Michel, additional, Fehr, Thomas, additional, Ferrari-Lacraz, Sylvie, additional, Garzoni, Christian, additional, Soccal, Paola G., additional, Gaudet, Christophe, additional, Giostra, Emiliano, additional, Golshayan, Déla, additional, Hadaya, Karine, additional, Halter, Jörg, additional, Hauri, Dimitri, additional, Heim, Dominik, additional, Hess, Christoph, additional, Hillinger, Sven, additional, Hirsch, Hans, additional, Hirt, Patricia, additional, Hofbauer, Günther, additional, Huynh-Do, Uyen, additional, Koller, Michael, additional, Laesser, Bettina, additional, Lang, Brian, additional, Lehmann, Roger, additional, Leichtle, Alexander, additional, Lovis, Christian, additional, Manuel, Oriol, additional, Marti, Hans-Peter, additional, Martin, Pierre Y., additional, Martinelli, Michele, additional, Mellac, Katell, additional, Merçay, Aurélia, additional, Mettler, Karin, additional, Meylan, Pascal, additional, Mueller, Nicolas, additional, Müller, Antonia, additional, Müller, Thomas, additional, Müller-Arndt, Ulrike, additional, Müllhaupt, Beat, additional, Nägeli, Mirjam, additional, Pascual, Manuel, additional, Posfay-Barbe, Klara, additional, Rick, Juliane, additional, Rosselet, Anne, additional, Rothlin, Silvia, additional, Ruschitzka, Frank, additional, Schanz, Urs, additional, Schaub, Stefan, additional, Schnyder, Aurelia, additional, Schuurmans, Macé, additional, Simonetta, Federico, additional, Staufer, Katharina, additional, Stampf, Susanne, additional, Steiger, Jürg, additional, Stirniman, Guido, additional, Stürzinger, Ueli, additional, Van Delden, Christian, additional, Venetz, Jean-Pierre, additional, Villard, Jean, additional, Vionnet, Julien, additional, Wick, Madeleine, additional, Wilhlem, Markus, additional, and Yerly, Patrick, additional

Published
2022
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37. Building Assessment Framework from Whole Building to Components

Author

Andersen, Kamilla Heimar, Melgaard, Simon Pommerencke, Jensen, Rasmus Lund, Fehr, Thomas, Marszal-Pomianowska, Anna, and Heiselberg, Per Kvols

Abstract

Well-functioning buildings are crucial for the occupant's health and comfort and for reducing the CO2 emissions from the building sector. A first step in assessing a well-functioning building is to know the current state of the building by, for example, relevant Key Performance Indicators (KPIs). Choosing suitable KPIs to provide a clear message can be challenging; however, beneficial to convey a message to the building actors. This study proposes a Building Assessment Framework to mitigate the latter, consisting of 1) a flexible and novel KPI tool and 2) a step-bystep KPI assessment methodology applicable to all buildings, systems, subsystems, and components. The KPI tool provides the user with a list of KPIs suited for all building systems, and with a separate backend and frontend, it is an easy tool to use. The KPI assessment methodology will guide the user through 5 steps and propose visualization of the chosen KPIs. The step-bystep KPI assessment methodology consists of 5 steps: 1) identification of the selected building resolution level 2) selection of the KPIs for the resolution level 3 + 4) recognition and crossreferencing of necessary sensors 5) choice of benchmarking for the data. The results from the KPI assessment using historical data from a university building located in Denmark demonstrate that the KPI tool is generic, making it applicable to all levels of a building and its systems. The Building Assessment Framework is flexible; it can be used over short and long periods (instantaneous to several years) and implemented in the building management system. However, it is necessary to be used with historical data, allowing for the real-time performance evaluation of the selected buildings or systems, thereby enabling the users to spot potential abnormal behavior that can lead to faults in the systems., CLIMA 2022 conference, 2022: CLIMA 2022 The 14th REHVA HVAC World Congress

Published
2022
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38. Building Assessment Framework from Whole Building to Components: A Danish Case Study

Author

Heimar Andersen Kamila, Pommerencke Melgaard Simon, Lund Jensen Rasmus, Fehr Thomas, Marszal-Pomianowska Anna, and Kvols Heiselberg Per

Subjects
Key Performance Indicators (KPIs), building systems, building assessment, energy use, rotary heat exchanger, air handling unit (AHU), open historical data
Abstract

Well-functioning buildings are crucial for the occupant's health and comfort and for reducing the CO2 emissions from the building sector. A first step in assessing a well-functioning building is to know the current state of the building by, for example, relevant Key Performance Indicators (KPIs). Choosing suitable KPIs to provide a clear message can be challenging; however, beneficial to convey a message to the building actors. This study proposes a Building Assessment Framework to mitigate the latter, consisting of 1) a flexible and novel KPI tool and 2) a step-bystep KPI assessment methodology applicable to all buildings, systems, subsystems, and components. The KPI tool provides the user with a list of KPIs suited for all building systems, and with a separate backend and frontend, it is an easy tool to use. The KPI assessment methodology will guide the user through 5 steps and propose visualization of the chosen KPIs. The step-bystep KPI assessment methodology consists of 5 steps: 1) identification of the selected building resolution level 2) selection of the KPIs for the resolution level 3 + 4) recognition and crossreferencing of necessary sensors 5) choice of benchmarking for the data. The results from the KPI assessment using historical data from a university building located in Denmark demonstrate that the KPI tool is generic, making it applicable to all levels of a building and its systems. The Building Assessment Framework is flexible; it can be used over short and long periods (instantaneous to several years) and implemented in the building management system. However, it is necessary to be used with historical data, allowing for the real-time performance evaluation of the selected buildings or systems, thereby enabling the users to spot potential abnormal behavior that can lead to faults in the systems.

Published
2022

39. First Testing of Literature-Based Models for Predicting Increase in Body Weight and Adipose Tissue Mass After Kidney Transplantation

Author

Schmid-Mohler, Gabriela; https://orcid.org/0000-0002-2610-636X, Beckmann, Sonja, Zala, Patrizia, Huber, Laura; https://orcid.org/0000-0003-0491-8452, Held, Ulrike, Fehr, Thomas, Wüthrich, Rudolf Peter, Petry, Heidi, Mueller, Thomas F, Schmid-Mohler, Gabriela; https://orcid.org/0000-0002-2610-636X, Beckmann, Sonja, Zala, Patrizia, Huber, Laura; https://orcid.org/0000-0003-0491-8452, Held, Ulrike, Fehr, Thomas, Wüthrich, Rudolf Peter, Petry, Heidi, and Mueller, Thomas F

Abstract

Introduction: Weight gain is a risk factor for poor clinical outcomes following kidney transplantation. Research Question: This study's aim was a first testing of 2 models to identify patients early after kidney transplantation who are at risk for weight gain and increase in adipose tissue mass in the first year after kidney transplantation. Design: The literature-based models were evaluated on longitudinal data of 88, respectively 79 kidney transplant recipients via ordinary and Firth regression, using gains ≥ 5% in weight and adipose tissue mass respectively as primary and secondary endpoints. Results: The models included physical activity, smoking cessation at time of kidney transplantation, self-reported health status, depressive symptomatology, gender, age, education, baseline body mass index and baseline trunk fat as predictors. Area under the curve was 0.797 (95%-CI 0.702 to 0.893) for the weight model and 0.767 (95%-CI 0.656 to 0.878) for the adipose tissue mass model-showing good, respectively fair discriminative ability. For weight gain ≥ 5%, main risk factors were smoking cessation at time of transplantation (OR 16.425, 95%-CI 1.737-155.288) and better self-reported baseline health state (OR 1.068 for each 1-unit increase, 95%-CI 1.012-1.128). For the adipose tissue mass gain ≥ 5%, main risk factor was overweight/obesity (BMI ≥ 25) at baseline (odds ratio 7.659, 95%-CI 1.789-32.789). Conclusions: The models have potential to assess patients' risk for weight or adipose tissue mass gain during the year after transplantation, but further testing is needed before implementation in clinical practice. Keywords: addictive; behavior; cardiovascular disease; clinical outcomes; depression; exercise outcomes; nutrition; performance improvement; quality; quality of life; quantitative methods; regression; research.

Published
2022

40. Successful Induction of Specific Immunological Tolerance by Combined Kidney and Hematopoietic Stem Cell Transplantation in HLA-Identical Siblings

Author

Fehr, Thomas; https://orcid.org/0000-0003-1668-1800, Hübel, Kerstin, de Rougemont, Olivier; https://orcid.org/0000-0001-8295-7911, Abela, Irene; https://orcid.org/0000-0002-5566-8628, Gaspert, Ariana, Güngör, Tayfun; https://orcid.org/0000-0002-3261-1186, Hauri, Mathias, Helmchen, Birgit, Linsenmeier, Claudia, Müller, Thomas; https://orcid.org/0000-0003-2236-2312, Nilsson, Jakob; https://orcid.org/0000-0001-5091-8133, Riesterer, Oliver; https://orcid.org/0000-0002-9508-0546, Scandling, John D, Schanz, Urs, Cippà, Pietro E; https://orcid.org/0000-0002-9507-0057, Fehr, Thomas; https://orcid.org/0000-0003-1668-1800, Hübel, Kerstin, de Rougemont, Olivier; https://orcid.org/0000-0001-8295-7911, Abela, Irene; https://orcid.org/0000-0002-5566-8628, Gaspert, Ariana, Güngör, Tayfun; https://orcid.org/0000-0002-3261-1186, Hauri, Mathias, Helmchen, Birgit, Linsenmeier, Claudia, Müller, Thomas; https://orcid.org/0000-0003-2236-2312, Nilsson, Jakob; https://orcid.org/0000-0001-5091-8133, Riesterer, Oliver; https://orcid.org/0000-0002-9508-0546, Scandling, John D, Schanz, Urs, and Cippà, Pietro E; https://orcid.org/0000-0002-9507-0057

Abstract

Induction of immunological tolerance has been the holy grail of transplantation immunology for decades. The only successful approach to achieve it in patients has been a combined kidney and hematopoietic stem cell transplantation from an HLA-matched or -mismatched living donor. Here, we report the first three patients in Europe included in a clinical trial aiming at the induction of tolerance by mixed lymphohematopoietic chimerism after kidney transplantation. Two female and one male patient were transplanted with a kidney and peripherally mobilized hematopoietic stem cells from their HLA-identical sibling donor. The protocol followed previous studies at Stanford University: kidney transplantation was performed on day 0 including induction with anti-thymocyte globulin followed by conditioning with 10x 1.2 Gy total lymphoid irradiation and the transfusion of CD34+ cells together with a body weight-adjusted dose of donor T cells on day 11. Immunosuppression consisted of cyclosporine A and steroids for 10 days, cyclosporine A and mycophenolate mofetil for 1 month, and then cyclosporine A monotherapy with tapering over 9-20 months. The 3 patients have been off immunosuppression for 4 years, 19 months and 8 months, respectively. No rejection or graft-versus-host disease occurred. Hematological donor chimerism was stable in the first, but slowly declining in the other two patients. A molecular microscope analysis in patient 2 revealed the genetic profile of a normal kidney. No relevant infections were observed, and the quality of life in all three patients is excellent. During the SARS-CoV-2 pandemic, all three patients were vaccinated with the mRNA vaccine BNT162b2 (Comirnaty®), and they showed excellent humoral and in 2 out 3 patients also cellular SARS-CoV-2-specific immunity. Thus, combined kidney and hematopoietic stem cell transplantation is a feasible and successful approach to induce specific immunological tolerance in the setting of HLA-matched sibling living kid

Published
2022

41. Impact of the COVID-19 pandemic on emergency outpatient consultations and admissions of non-COVID-19 patients (ECCO)—A cross-sectional study

Author

Kuo, Yong-Hong, Kuo, Y ( Yong-Hong ), Hangartner, Nina; https://orcid.org/0000-0002-9124-1939, Di Gangi, Stefania, Elbl, Christoph, Senn, Oliver; https://orcid.org/0000-0003-4422-7250, Bisatz, Fadri, Fehr, Thomas, Kuo, Yong-Hong, Kuo, Y ( Yong-Hong ), Hangartner, Nina; https://orcid.org/0000-0002-9124-1939, Di Gangi, Stefania, Elbl, Christoph, Senn, Oliver; https://orcid.org/0000-0003-4422-7250, Bisatz, Fadri, and Fehr, Thomas

Abstract

During the first year of the COVID-19 pandemic, healthcare facilities worldwide struggled to adequately care for the increasing number of COVID-19 patients while maintaining quality of care for all other patients. The aim of this study was to investigate the displacement and underuse of non-COVID-19 patient care in a medical department of a tertiary hospital in Switzerland. In this retrospective cross-sectional study, internal medicine admissions from 2017 to 2020, emergency outpatient visits from 2019 to 2020 and COVID-19 admissions in 2020 were analyzed and compared using a regression model. Internal medicine admissions were also stratified by diagnosis. A questionnaire was used to assess the pandemic experience of local general practitioners, referring hospitals, and nursing homes. The total number of admissions decreased during the 1st and 2nd waves of the pandemic but increased between the two waves. Elective admissions decreased in 2020 compared to pre-pandemic years: they represented 25% of total admissions in 2020 versus 30% of the total admissions during 2017–2019, p <0.001. Admissions for emergency reasons increased: 71% in 2020 versus 65% in 2017–2019, p < 0.001. Emergency outpatient consultations decreased in 2020 compared to 2019, 62.77 (14.70), mean (SD), weekly visits in 2020 versus 74.13 (13.98) in 2019, p<0.001. Most general practitioners and heads of referring hospitals also reported a decrease in consultations, especially during the 1st wave of the pandemic. Mental illnesses, anxiety or burn-out were perceived in both patients and staff in general practices and nursing homes. In conclusion, the COVID-19 pandemic negatively affected the care of non-COVID-19 patients, particularly those with chronic illnesses. A shift of health care resources from non-COVID patients to COVID patients was observed. These findings could help institutions better manage such a situation in the future.

Published
2022

43. BK Polyomavirus‐Specific 9mer CD8 T Cell Responses Correlate With Clearance of BK Viremia in Kidney Transplant Recipients: First Report From the Swiss Transplant Cohort Study

Author

Leboeuf, C., Wilk, S., Achermann, R., Binet, I., Golshayan, D., Hadaya, K., Hirzel, C., Hoffmann, M., Huynh‐Do, U., Koller, M. T., Manuel, O., Mueller, N. J., Mueller, T. F., Schaub, S., van Delden, C., Weissbach, F. H., Hirsch, H. H., Amico, Patrizia, Aubert, John‐David, Banz, Vanessa, Beldi, Guido, Benden, Christian, Berger, Christoph, Bochud, Pierre‐Yves, Bucher, Heiner, Bühler, Leo, Carell, Thierry, Catana, Emmanuelle, Chalandon, Yves, de Geest, Sabina, de Rougemont, Olivier, Dickenmann, Michael, Duchosal, Michel, Elkrief, Laure, Fehr, Thomas, Ferrari‐Lacraz, Sylvie, Garzoni, Christian, Soccal, Paola Gasche, Gaudet, Christophe, Giostra, Emiliano, Halter, Jörg, Heim, Dominik, Hess, Christoph, Hillinger, Sven, Hofbauer, Günther, Immer, Franz, Klaghofer, Richard, Laesser, Bettina, Lehmann, Roger, Lovis, Christian, Marti, Hans‐Peter, Martin, Pierre Yves, Meylan, Pascal, Mohacsi, Paul, Morel, Philippe, Mueller, Ulrike, Mueller‐McKenna, Helen, Müller, Antonia, Müller, Thomas, Müllhaupt, Beat, Nadal, David, Pascual, Manuel, Passweg, Jakob, Rick, Juliane, Roosnek, Eddy, Rosselet, Anne, Rothlin, Silvia, Ruschitzka, Frank, Schanz, Urs, Schnyder, Aurelia, Seiler, Christian, Stampf, Susanne, Steiger, Jürg, Stirnimann, Guido, Toso, Christian, Venetz, Jean‐Pierre, Villard, Jean, Wick, Madeleine, Wilhelm, Markus, and Yerly, Patrick

Published
2017
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45. ExplorinG frailty and mild cognitive impairmEnt in kidney tRansplantation to predict biomedicAl, psychosocial and health cost outcomeS (GERAS): protocol of a nationwide prospective cohort study

Author

Mauthner, Oliver, Claes, Veerle, Walston, Jeremy, Engberg, Sandra, Binet, Isabelle, Dickenmann, Michael, Golshayan, Déla, Hadaya, Karine, Huynh‐Do, Uyen, Calciolari, Stefano, De Geest, Sabina, Berben, Lut, Burkhalter, Hanna, Denhaerynck, Kris, Helmy, Remon, Kirsch, Monika, Leppla, Lynn, Struker, Marian, Boehler, Annette, Gerull, Sabine, Koller, Michael T, Boely, Elsa, Catana, Emmanuelle, Simcox, Amira, Seiler, Annina, Klaghofer, Richard, Künzler‐Heule, Patrizia, Beckmann, Sonja, Achermann, Rita, Amico, Patrizia, Aubert, John‐David, Baumann, Philippe, Beldi, Guido, Benden, Christian, Berger, Christoph, Bochud, Pierre‐Yves, Boely, Elsa, Bucher, Heiner, Bühler, Leo, Carell, Thierry, Catana, Emmanuelle, Chalandon, Yves, de Rougemont, Olivier, Duchosal, Michel, Fehr, Thomas, Ferrari‐Lacraz, Sylvie, Garzoni, Christian, Soccal, Paola Gasche, Giostra, Emiliano, Halter, Jörg, Heim, Dominik, Hess, Christoph, Hillinger, Sven, Hirsch, Hans H., Hofbauer, Günther, Immer, Franz, Klaghofer, Richard, Koller, Michael, Laesser, Bettina, Lehmann, Roger, Lovis, Christian, Manuel, Oriol, Marti, Hans‐Peter, Martin, Pierre Yves, Martinolli, Luca, Meylan, Pascal, Mohacsi, Paul, Morard, Isabelle, Morel, Philippe, Mueller, Ulrike, Mueller, Nicolas J, Mueller‐McKenna, Helen, Müller, Antonia, Müller, Thomas, Müllhaupt, Beat, Nadal, David, Pascual, Manuel, Passweg, Jakob, Ziegler, Chantal Piot, Rick, Juliane, Roosnek, Eddy, Rosselet, Anne, Rothlin, Silvia, Ruschitzka, Frank, Schanz, Urs, Schaub, Stefan, Schnyder, Aurelia, Seiler, Christian, Stampf, Susanne, Steiger, Jürg, Stirnimann, Guido, Toso, Christian, Van Delden, Christian, Venetz, Jean‐Pierre, Villard, Jean, Wick, Madeleine, Wilhelm, Markus, and Yerly, Patrick

Published
2017
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48. Development and description of the SATO KPI Tool

Author

Andersen, Kamilla Heimar, Melgaard, Simon Pommerencke, Marszal-Pomianowska, Anna, Jensen, Rasmus Lund, Fehr, Thomas, and Heiselberg, Per

Subjects
KPI Tool, Key performance indicator (KPI), SATO H2020 project, SDG 12 - Responsible Consumption and Production, SDG 11 - Sustainable Cities and Communities
Abstract

This document describes the development of the SATO KPI Tool in relation to the H2020 SATO Project.

Published
2022

50. Successful Induction of Specific Immunological Tolerance by Combined Kidney and Hematopoietic Stem Cell Transplantation in HLA-Identical Siblings

Author

Fehr, Thomas, primary, Hübel, Kerstin, additional, de Rougemont, Olivier, additional, Abela, Irene, additional, Gaspert, Ariana, additional, Güngör, Tayfun, additional, Hauri, Mathias, additional, Helmchen, Birgit, additional, Linsenmeier, Claudia, additional, Müller, Thomas, additional, Nilsson, Jakob, additional, Riesterer, Oliver, additional, Scandling, John D., additional, Schanz, Urs, additional, and Cippà, Pietro E., additional

Published
2022
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