185 results on '"Eggleston, Ian M."'
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2. Tripodal BODIPY‐Tagged and Functional Molecular Probes: Synthesis, Computational Investigations and Explorations by Multiphoton Fluorescence Lifetime Imaging Microscopy.
3. Biofilm-specific uptake of a 4-pyridone-based iron chelator by Pseudomonas aeruginosa
4. An intestinal paracellular pathway biased toward positively-charged macromolecules
5. Mechanistic studies of a cell-permeant peptide designed to enhance myosin light chain phosphorylation in polarized intestinal epithelia
6. Peptide-Targeted Photosensitisers: Synthesis and Applications in Photobiology
7. Chemical approaches for the enhancement of 5-aminolevulinic acid-based photodynamic therapy and photodiagnosis
8. Enhanced paracellular transport of insulin can be achieved via transient induction of myosin light chain phosphorylation
9. (Digital Presentation) Peptide Targeting of Photosensitisers for Photodynamic Therapy and Drug Delivery Applications
10. Photochemical internalisation of a macromolecular protein toxin using a cell penetrating peptide-photosensitiser conjugate
11. Daylight-PDT: everything under the sun
12. Effective photoinactivation of Gram-positive and Gram-negative bacterial strains using an HIV-1 Tat peptide—porphyrin conjugate
13. SPPS of the Natural Product Chitinase Inhibitor Argifin: Library Generation and Biological Evaluation
14. Synthesis and Structure-based Dissection of Cyclic Peptide Chitinase Inhibitors: New Leads for Antifungal and Anti-Inflammatory Drugs
15. The cancer chemopreventive actions of phytochemicals derived from glucosinolates
16. Structural insights into the mechanism and inhibition of eukaryotic O‐GlcNAc hydrolysis
17. Codelivery of a cytotoxin and photosensitiser via a liposomal nanocarrier: a novel strategy for light-triggered cytosolic release† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8nr04048f
18. Efficient synthesis of 1,3,7-substituted xanthines by a safety-catch protection strategy
19. Structural Investigations, Cellular Imaging, and Radiolabeling of Neutral, Polycationic, and Polyanionic Functional Metalloporphyrin Conjugates
20. Time-dependent inhibitors of trypanothione reductase: Analogues of the spermidine alkaloid lunarine and related natural products
21. Peptide Targeting of Photosensitisers for Photodynamic Therapy and Drug Delivery
22. 1-Cyano-2,3-epithiopropane is a novel plant-derived chemopreventive agent which induces cytoprotective genes that afford resistance against the genotoxic α,β-unsaturated aldehyde acrolein
23. Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents
24. An efficient synthesis of 5-aminolaevulinic acid (ALA)-containing peptides for use in photodynamic therapy
25. Specificity of the trypanothione-dependent Leishmania major glyoxalase I: structure and biochemical comparison with the human enzyme
26. Benzofuranyl 3,5-bis-Polyamine derivatives as time-Dependent inhibitors of trypanothione reductase
27. Development of a peptide-based fluorescent probe for biological heme monitoring
28. Cyclo-(L-histidylglycyl-L-prolylglycyl-L-prolylglycine)
29. Solid-phase synthesis of cyclic peptide chitinase inhibitors: SAR of the argifin scaffold† †Electronic supplementary information (ESI) available: ES-MS data for compounds 10a and 10b. See DOI: 10.1039/b815077j Click here for additional data file
30. Endolysosomal targeting of a clinical chlorin photosensitiser for light-triggered delivery of nano-sized medicines
31. Abstract B38: Photochemical internalisation for the local delivery of chemotherapy in prostate cancer
32. The Use of Dipeptide Derivatives of 5-Aminolaevulinic Acid Promotes Their Entry to Tumor Cells and Improves Tumor Selectivity of Photodynamic Therapy
33. A fluorescent Arg–Gly–Asp (RGD) peptide–naphthalenediimide (NDI) conjugate for imaging integrin αvβ3in vitro
34. Bioactive components in foods
35. Fluorescence Lifetime Imaging and FRET‐Induced Intracellular Redistribution of Tat‐Conjugated Quantum Dot Nanoparticles through Interaction with a Phthalocyanine Photosensitiser
36. Quantitative determination of 5-aminolaevulinic acid and its esters in cell lysates by HPLC-fluorescence
37. Human YKL-39 is a pseudo-chitinase with retained chitooligosaccharide-binding properties
38. Analyzing Airway Inflammation with Chemical Biology: Dissection of Acidic Mammalian Chitinase Function with a Selective Drug-like Inhibitor
39. Bisdionin C—A Rationally Designed, Submicromolar Inhibitor of Family 18 Chitinases
40. Natural Product–Guided Discovery of a Fungal Chitinase Inhibitor
41. ChemInform Abstract: Regiocontrolled Synthesis of the Macrocyclic Polyamine Alkaloid (.+-.)-Lunarine, a Time-Dependent Inhibitor of Trypanothione Reductase.
42. Novel prodrug approach to photodynamic therapy: Fmoc solid-phase synthesis of a cell permeable peptide incorporating 5-aminolaevulinic acid
43. Improved Peptide Prodrugs of 5-ALA for PDT: Rationalization of Cellular Accumulation and Protoporphyrin IX Production by Direct Determination of Cellular Prodrug Uptake and Prodrug Metabolization
44. Solid-phase synthesis of cyclic peptide chitinase inhibitors: SAR of the argifin scaffold
45. ChemInform Abstract: Convenient Preparation of N-Maleoyl Amino Acid Succinimido Esters Using N-Trifluoroacetoxysuccinimide.
46. 5-Aminolaevulinic acid peptide prodrugs enhance photosensitization for photodynamic therapy
47. ChemInform Abstract: Efficient Synthesis of 1,3,7‐Substituted Xanthines by a Safety‐Catch Protection Strategy.
48. Structure-Based Dissection of the Natural Product Cyclopentapeptide Chitinase Inhibitor Argifin
49. Convenient Preparation ofN‐Maleoyl Amino Acid Succinimido Esters usingN‐Trifluoroacetoxysuccinimide
50. First Synthesis of Argadin: A Nanomolar Inhibitor of Family-18 Chitinases
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