430 results on '"Economides, Aris N"'
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2. Converging evidence from exome sequencing and common variants implicates target genes for osteoporosis
3. Odd skipped-related 1 controls the pro-regenerative response of fibro-adipogenic progenitors
4. Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity
5. Antibodies to sclerostin or G-CSF receptor partially eliminate bone or marrow adipocyte loss, respectively, following vertical sleeve gastrectomy
6. Regulation of sensorimotor gating via Disc1/Huntingtin-mediated Bdnf transport in the cortico-striatal circuit
7. Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes
8. Comparative Transcriptomics Identifies Novel Genes and Pathways Involved in Post-Traumatic Osteoarthritis Development and Progression.
9. SOST/Sclerostin Improves Posttraumatic Osteoarthritis and Inhibits MMP2/3 Expression After Injury
10. Global molecular changes in a tibial compression induced ACL rupture model of post‐traumatic osteoarthritis
11. Wnt co-receptors Lrp5 and Lrp6 differentially mediate Wnt3a signaling in osteoblasts
12. Noncoding RNA processing by DIS3 regulates chromosomal architecture and somatic hypermutation in B cells
13. Activin A does not drive post-traumatic heterotopic ossification
14. Lysosomal degradation of ACVR1-Activin complexes negatively regulates signaling of Activins and Bone Morphogenetic Proteins
15. How Activin A Became a Therapeutic Target in Fibrodysplasia Ossificans Progressiva
16. Sostdc1 deficiency accelerates fracture healing by promoting the expansion of periosteal mesenchymal stem cells.
17. Sclerostin antibody treatment improves fracture outcomes in a Type I diabetic mouse model
18. Structural characterization of an activin class ternary receptor complex reveals a third paradigm for receptor specificity
19. Anti-ACVRI antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressive (FOP) by activating FOP-mutant ACVR1
20. THU402 New Heterotopic Ossification Lesions In Patients With Fibrodysplasia Ossificans Progressiva Measured By PET/CT vs CT Only
21. OR29-06 Flare-Ups In Patients With Fibrodysplasia Ossificans Progressiva Reduced By Garetosmab Treatment: LUMINA-1 Data
22. Skeletal phenotype amelioration in Mucopolysaccharidosis VI requires intervention at the earliest stages of postnatal development
23. Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP
24. Sost and its paralog Sostdc1 coordinate digit number in a Gli3-dependent manner.
25. Induction of the Hajdu-Cheney Syndrome Mutation in CD19 B Cells in Mice Alters B-Cell Allocation but Not Skeletal Homeostasis
26. The obligatory role of Activin A in the formation of heterotopic bone in Fibrodysplasia Ossificans Progressiva
27. Resistance to Diet-Induced Obesity in Mice Globally Overexpressing OGH/GPB5
28. Activin E–ACVR1C cross talk controls energy storage via suppression of adipose lipolysis in mice
29. Human Disease-Causing NOG Missense Mutations: Effects on Noggin Secretion, Dimer Formation, and Bone Morphogenetic Protein Binding
30. Sostdc1 deficiency accelerates fracture healing by promoting the expansion of periosteal mesenchymal stem cells
31. Sclerostin antibody treatment improves fracture outcomes in a Type I diabetic mouse model
32. Garetosmab, an inhibitor of activin A, reduces heterotopic ossification and flare-ups in adults with fibrodysplasia ossificans progressiva: a randomized, double-blind, placebo-controlled phase 2 trial
33. TMPRSS6 Inhibition with a Monoclonal Antibody Improves Red Blood Cell Health and Reduces Hepatic Iron Loading in Mouse Models of Iron Overload Diseases
34. Inhibition of leukemia cell engraftment and disease progression in mice by osteoblasts
35. Dissection of bone morphogenetic protein signaling using genome-engineering tools
36. Odd skipped-related 1 controls the pro-regenerative response of Fibro-Adipogenic Progenitors
37. Conditionals by inversion provide a universal method for the generation of conditional alleles
38. Targeted deletion of Sost distal enhancer increases bone formation and bone mass
39. Liver-specific AAV gene therapy corrects lipid storage in LAL-D model mice but does not prevent lipid accumulation in acquired fatty liver model mice
40. Connective tissue growth factor acts within both endothelial cells and β cells to promote proliferation of developing β cells
41. Angiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor
42. Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region
43. Cell type-selective targeted delivery of a recombinant lysosomal enzyme for enzyme therapies
44. A lymphatic defect causes ocular hypertension and glaucoma in mice
45. Neural Induction by the Secreted Polypeptide Noggin
46. ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1
47. Garetosmab Reduces Flare-ups in Patients With Fibrodysplasia Ossificans Progressiva
48. Loss of the BMP antagonist USAG-1 ameliorates disease in a mouse model of the progressive hereditary kidney disease Alport syndrome
49. Saracatinib is an efficacious clinical candidate for fibrodysplasia ossificans progressiva
50. Anti-GDF11Treatment of β-Thalassemia Intermedia Mice Does Not Improve Erythropoiesis
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