Search

Your search keyword '"Dorans, Kirsten S."' showing total 47 results
Start Over Author "Dorans, Kirsten S." Publication Year Range Last 50 years
47 results on '"Dorans, Kirsten S."'

9. Social, Behavioral, and Metabolic Risk Factors and Racial Disparities in Cardiovascular Disease Mortality in U.S. Adults

Author

He, Jiang, primary, Bundy, Joshua D., additional, Geng, Siyi, additional, Tian, Ling, additional, He, Hua, additional, Li, Xingyan, additional, Ferdinand, Keith C., additional, Anderson, Amanda H., additional, Dorans, Kirsten S., additional, Vasan, Ramachandran S., additional, Mills, Katherine T., additional, and Chen, Jing, additional

Published
2023
Full Text
View/download PDF

12. Effects of a Low-Carbohydrate Dietary Intervention on Hemoglobin A1c

Author

Dorans, Kirsten S., primary, Bazzano, Lydia A., additional, Qi, Lu, additional, He, Hua, additional, Chen, Jing, additional, Appel, Lawrence J., additional, Chen, Chung-Shiuan, additional, Hsieh, Ming-Hui, additional, Hu, Frank B., additional, Mills, Katherine T., additional, Nguyen, Bernadette T., additional, O’Brien, Matthew J., additional, Samet, Jonathan M., additional, Uwaifo, Gabriel I., additional, and He, Jiang, additional

Published
2022
Full Text
View/download PDF

15. Associations of Anxiety during the COVID-19 Pandemic with Patient Characteristics and Behaviors in CKD Patients: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study

Author

Dorans, Kirsten S., primary, Wright Nunes, Julie A., additional, Schaubel, Douglas E., additional, Sha, Daohang, additional, Schrauben, Sarah J., additional, Nelson, Robert G., additional, Rao, Panduranga S., additional, Cohen, Debbie L., additional, Appel, Lawrence J., additional, Lash, James P., additional, Rahman, Mahboob, additional, and Feldman, Harold I., additional

Published
2022
Full Text
View/download PDF

16. 550-P: A Randomized Trial of Low-Carbohydrate Diet on Hemoglobin A1c among Individuals with Elevated Hemoglobin A1c

Author

DORANS, KIRSTEN S., primary, BAZZANO, LYDIA A., additional, QI, LU, additional, HE, HUA, additional, CHEN, JING, additional, APPEL, LAWRENCE J., additional, HU, FRANK, additional, SAMET, JONATHAN, additional, MILLS, KATHERINE T., additional, O'BRIEN, MATTHEW J., additional, UWAIFO, GABRIEL I., additional, and HE, JIANG, additional

Published
2022
Full Text
View/download PDF

22. Low-carbohydrate Dietary Pattern on Glycemic Outcomes Trial (ADEPT) among Individuals with Elevated Hemoglobin A1c: Study Protocol for a Randomized Controlled Trial

Author

Dorans, Kirsten S., primary, Bazzano, Lydia A., additional, Qi, Lu, additional, He, Hua, additional, Appel, Lawrence J., additional, Samet, Jonathan M., additional, Chen, Jing, additional, Mills, Katherine T., additional, Nguyen, Bernadette T., additional, O'Brien, Matthew J., additional, Uwaifo, Gabriel I., additional, and He, Jiang, additional

Published
2020
Full Text
View/download PDF

25. Change in ankle–brachial index and mortality among individuals with chronic kidney disease: findings from the Chronic Renal Insufficiency Cohort Study.

Author

Dorans, Kirsten S, He, Hua, Chen, Jing, Dobre, Mirela, Go, Alan S, Hamm, L Lee, Jaar, Bernard G, Mehta, Rupal C, Rahman, Mahboob, Ricardo, Ana C, Rosas, Sylvia E, Srivastava, Anand, He, Jiang, and Investigators, the CRIC Study

Subjects
*CHRONIC kidney failure, *ANKLE brachial index, *LEG amputation, *COHORT analysis, *PERIPHERAL vascular diseases
Abstract

Background Patients with chronic kidney disease (CKD) have an increased risk of peripheral arterial disease (PAD). The ankle–brachial index (ABI), a noninvasive measure of PAD, is a predictor of adverse events among individuals with CKD. In general populations, changes in ABI have been associated with mortality, but this association is not well understood among patients with CKD. Methods We conducted a prospective study of 2920 participants in the Chronic Renal Insufficiency Cohort Study without lower extremity revascularization or amputation at baseline and with at least one follow-up ABI measurement (taken at annual visits) during the first 4 years of follow-up. The ABI was obtained by the standard protocol. Results In Cox proportional hazard regression analyses, we found a U-shaped association of average annual change in ABI with all-cause mortality. After adjusting for baseline ABI and other covariates, compared with participants with an average annual change in ABI of 0–<0.02, individuals with an average annual change in ABI <−0.04 or ≥0.04 had multivariable-adjusted hazard ratios (HRs) of 1.81 [95% confidence interval (CI) 1.34–2.44) and 1.42 (95% CI 1.12–1.82) for all-cause mortality, respectively. Compared with the cumulative average ABI of 1.0–<1.4, multivariable-adjusted HRs for those with a cumulative average ABI of <0.9, 0.9–<1.0 and ≥1.4 were 1.93 (95% CI 1.42–2.61), 1.20 (0.90–1.62) and 1.31 (0.94–1.82), respectively. Conclusions This study indicates both larger decreases and increases in average annual changes in ABI (>0.04/year) were associated with higher mortality risk. Monitoring changes in ABI over time may facilitate risk stratification for mortality among individuals with CKD. [ABSTRACT FROM AUTHOR]

Published
2021
Full Text
View/download PDF

26. IS THIS A PORTRAIT OF JOHN GRAUNT? AN ART HISTORY MYSTERY

Author

Murray, Eleanor J, primary, Farland, Leslie V, additional, Caniglia, Ellen C, additional, Dorans, Kirsten S, additional, DuPre, Natalie C, additional, Hughes, Katherine C, additional, Kim, Iris Y, additional, Pernar, Claire H, additional, Tanz, Lauren J, additional, and Zack, Rachel M, additional

Published
2019
Full Text
View/download PDF

27. IS THIS A PORTRAIT OF JOHN GRAUNT? AN ART HISTORY MYSTERY.

Author

Murray, Eleanor J, Farland, Leslie V, Caniglia, Ellen C, Dorans, Kirsten S, DuPre, Natalie C, Hughes, Katherine C, Kim, Iris Y, Pernar, Claire H, Tanz, Lauren J, and Zack, Rachel M

Subjects
ART history, PUBLIC health, DIARY (Literary form)
Abstract

In the article, the authors examine whether the mid-1650 portrait titled "Unknown Man" is a portrait of Englishman John Graunt, who worked on the environmental and societal factors of mortality and morbidity. Also cited are Graunt's book "Natural and Political Observations Made on the Bills of Mortality," the efforts by John Graunt Society members to find a photograph of Graunt, and a brief history of the "Unknown Man" portrait.

Published
2020
Full Text
View/download PDF

29. Residential proximity to major roadways, fine particulate matter, and adiposity: The framingham heart study

Author

Li, Wenyuan, Dorans, Kirsten S., Wilker, Elissa H., Rice, Mary B., Schwartz, Joel, Coull, Brent A., Koutrakis, Petros, Gold, Diane R., Fox, Caroline S., and Mittleman, Murray A.

Subjects
Adult, Male, Air Pollutants, Subcutaneous Fat, Environmental Exposure, Intra-Abdominal Fat, Middle Aged, Article, Logistic Models, Linear Models, Humans, Female, Particulate Matter, Obesity, Vehicle Emissions, Adiposity, Environmental Monitoring
Abstract

Higher traffic-related air pollution has been associated with higher body mass index (BMI) among children. However, few studies have assessed the associations among adults.Participants (N = 2,372) from the Framingham Offspring and Third Generation cohorts who underwent multidetector-computed tomography scans (2002-2005) were included. Residential-based proximity to the nearest major roadway and 1-year average levels of fine particulate matter (PMParticipants who lived 60 m from a major roadway had 0.37 kg/mLiving closer to a major roadway was associated with higher overall and abdominal adiposity.

Published
2016

30. Abstract P066: Shot-term Exposure to Ambient Air Pollution and Circulating Biomarkers of Systemic Inflammation: The Framingham Heart Study

Author

Li, Wenyuan, primary, Wilker, Elissa H, additional, Dorans, Kirsten S, additional, Rice, Mary B, additional, Ljungman, Petter L, additional, Schwartz, Joel, additional, Coull, Brent A, additional, Koutrakis, Petros, additional, Gold, Diane R, additional, Benjamin, Emelia J, additional, Vasan, Ramachandran S, additional, and Mittleman, Murray A, additional

Published
2017
Full Text
View/download PDF

31. Residential proximity to major roads, exposure to fine particulate matter and aortic calcium: the Framingham Heart Study, a cohort study

Author

Dorans, Kirsten S, primary, Wilker, Elissa H, additional, Li, Wenyuan, additional, Rice, Mary B, additional, Ljungman, Petter L, additional, Schwartz, Joel, additional, Coull, Brent A, additional, Kloog, Itai, additional, Koutrakis, Petros, additional, D'Agostino, Ralph B, additional, Massaro, Joseph M, additional, Hoffmann, Udo, additional, O'Donnell, Christopher J, additional, and Mittleman, Murray A, additional

Published
2017
Full Text
View/download PDF

32. Chocolate intake and incidence of heart failure : Findings from the Cohort of Swedish Men.

Author

Steinhaus, Daniel A, Mostofsky, Elizabeth, Levitan, Emily B, Dorans, Kirsten S, Håkansson, Niclas, Wolk, Alicja, Mittleman, Murray A, Steinhaus, Daniel A, Mostofsky, Elizabeth, Levitan, Emily B, Dorans, Kirsten S, Håkansson, Niclas, Wolk, Alicja, and Mittleman, Murray A

Abstract

The objective of this study was to evaluate the association of chocolate consumption and heart failure (HF) in a large population of Swedish men. METHODS: We conducted a prospective cohort study of 31,917 men 45-79 years old with no history of myocardial infarction, diabetes, or HF at baseline who were participants in the population-based Cohort of Swedish Men study. Chocolate consumption was assessed through a self-administrated food frequency questionnaire. Participants were followed for HF hospitalization or mortality from January 1, 1998, to December 31, 2011, using record linkage to the Swedish inpatient and cause-of-death registries. RESULTS: During 14 years of follow-up, 2,157 men were hospitalized (n=1,901) or died from incident HF (n=256). Compared with subjects who reported no chocolate intake, the multivariable-adjusted rate ratio of HF was 0.88 (95% CI 0.78-0.99) for those consuming 1-3 servings per month, 0.83 (95% CI 0.72-0.94) for those consuming 1-2 servings per week, 0.82 (95% CI 0.68-0.99) for those consuming 3-6 servings per week, and 1.10 (95% CI 0.84-1.45) for those consuming ≥1 serving per day (P for quadratic trend=.001). CONCLUSIONS: In this large prospective cohort study, there was a J-shaped relationship between chocolate consumption and HF incidence. Moderate chocolate consumption was associated with a lower rate of HF hospitalization or death, but the protective association was not observed among individuals consuming ≥1 serving per day. Journal Subject Codes: Etiology: Epidemiology, Heart failure: Congestive.

Published
2017
Full Text
View/download PDF

34. Residential Proximity to Major Roads, Exposure to Fine Particulate Matter, and Coronary Artery Calcium

Author

Dorans, Kirsten S., primary, Wilker, Elissa H., additional, Li, Wenyuan, additional, Rice, Mary B., additional, Ljungman, Petter L., additional, Schwartz, Joel, additional, Coull, Brent A., additional, Kloog, Itai, additional, Koutrakis, Petros, additional, D’Agostino, Ralph B., additional, Massaro, Joseph M., additional, Hoffmann, Udo, additional, O’Donnell, Christopher J., additional, and Mittleman, Murray A., additional

Published
2016
Full Text
View/download PDF

35. Short‐Term Exposure to Air Pollution and Biomarkers of Oxidative Stress: The Framingham Heart Study

Author

Li, Wenyuan, primary, Wilker, Elissa H., additional, Dorans, Kirsten S., additional, Rice, Mary B., additional, Schwartz, Joel, additional, Coull, Brent A., additional, Koutrakis, Petros, additional, Gold, Diane R., additional, Keaney, John F., additional, Lin, Honghuang, additional, Vasan, Ramachandran S., additional, Benjamin, Emelia J., additional, and Mittleman, Murray A., additional

Published
2016
Full Text
View/download PDF

36. Abstract P065: Exposure to Traffic and Fine Particulate Matter and Aortic Calcium in the Framingham Offspring and Third Generation Cohorts

Author

Dorans, Kirsten S, primary, Wilker, Elissa H, additional, Li, Wenyuan, additional, Rice, Mary B, additional, Ljungman, Petter L, additional, Schwartz, Joel, additional, Coull, Brent A, additional, Buring, Julie E, additional, Kloog, Itai, additional, Koutrakis, Petros, additional, D’Agostino, Ralph B, additional, Massaro, Joseph M, additional, Hoffmann, Udo, additional, O’Donnell, Christopher J, additional, and Mittleman, Murray A, additional

Published
2016
Full Text
View/download PDF

37. Alcohol and Incident Heart Failure Among Middle-Aged and Elderly Men Cohort of Swedish Men

Author

Dorans, Kirsten S., Mostofsky, Elizabeth, Levitan, Emily B., Hakansson, Niclas, Wolk, Alicja, Mittleman, Murray A., Dorans, Kirsten S., Mostofsky, Elizabeth, Levitan, Emily B., Hakansson, Niclas, Wolk, Alicja, and Mittleman, Murray A.

Abstract

Background Compared with no alcohol consumption, heavy alcohol intake is associated with a higher rate of heart failure (HF) whereas light-to-moderate intake may be associated with a lower rate. However, several prior studies did not exclude former drinkers, who may have changed alcohol consumption in response to diagnosis. This study aimed to investigate the association between alcohol intake and incident HF. Methods and Results We conducted a prospective cohort study of 33 760 men aged 45 to 79 years with no HF, diabetes mellitus, or myocardial infarction at baseline participating in the Cohort of Swedish Men Study. We excluded former drinkers. At baseline, participants completed a food frequency questionnaire and reported other characteristics. HF was defined as hospitalization for or death from HF, ascertained by Swedish inpatient and cause-of-death records from January 1, 1998, through December 31, 2011. We constructed Cox proportional hazards models to estimate multivariable-adjusted incidence rate ratios. During follow-up, 2916 men were hospitalized for (n=2139) or died (n=777) of incident HF. There was a U-shaped relationship between total alcohol intake and incident HF (P=0.0004). There was a nadir at light-to-moderate alcohol intake: consuming 7 to <14 standard drinks per week was associated with a 19% lower multivariable-adjusted rate of HF compared with never drinking (incidence rate ratio, 0.81; 95% confidence interval, 0.69-0.96). Conclusions In this cohort of Swedish men, there was a U-shaped relationship between alcohol consumption and HF incidence, with a nadir at light-to-moderate intake. Heavy intake did not seem protective.

Published
2015
Full Text
View/download PDF

39. Residential Proximity toMajor Roadways, Fine ParticulateMatter, and Hepatic Steatosis: The FraminghamHeart Study.

Author

Wenyuan Li, Dorans, Kirsten S., Wilker, Elissa H., Rice, Mary B., Long, Michelle T., Schwartz, Joel, Coull, Brent A., Koutrakis, Petros, Gold, Diane R., Fox, Caroline S., and Mittleman, Murray A.

Subjects
*AIR pollution, *COMPUTED tomography, *CONFIDENCE intervals, *FATTY liver, *POPULATION geography, *REGRESSION analysis, *PARTICULATE matter, *ODDS ratio
Abstract

We examined associations between ambient air pollution and hepatic steatosis among 2,513 participants from the Framingham (Massachusetts) Offspring Study and Third Generation Cohort who underwent a computed tomography scan (2002-2005), after excluding men who reported >21 drinks/week and women who reported >14 drinks/week. We calculated each participant's residential-based distance to a major roadway and used a spatiotemporal model to estimate the annual mean concentrations of fine particulate matter. Liver attenuation was measured by computed tomography, and liver-to-phantom ratio (LPR) was calculated. Lower values of LPR represent more liver fat. We estimated differences in continuous LPR using linear regression models and prevalence ratios for presence of hepatic steatosis (LPR ≤ 0.33) using generalized linear models, adjusting for demographics, individual and area-level measures of socioeconomic position, and clinical and lifestyle factors. Participants who lived 58 m (25th percentile) from major roadways had lower LPR (β = -0.003, 95% confidence interval: -0.006, -0.001) and higher prevalence of hepatic steatosis (prevalence ratio = 1.16, 95% confidence interval: 1.05, 1.28) than those who lived 416 m (75th percentile) away. The 2003 annual average fine particulate matter concentration was not associated with liver-fat measurements. Our findings suggest that living closer to major roadways was associated with more liver fat. [ABSTRACT FROM AUTHOR]

Published
2017
Full Text
View/download PDF

44. Residential proximity to major roads, exposure to fine particulate matter and aortic calcium: the Framingham Heart Study, a cohort study

Author

Dorans, Kirsten S, Wilker, Elissa H, Li, Wenyuan, Rice, Mary B, Ljungman, Petter L, Schwartz, Joel, Coull, Brent A, Kloog, Itai, Koutrakis, Petros, D'Agostino, Ralph B, Massaro, Joseph M, Hoffmann, Udo, O'Donnell, Christopher J, and Mittleman, Murray A

Subjects
EPIDEMIOLOGY, PUBLIC HEALTH
Abstract

Objectives: Traffic and ambient air pollution exposure are positively associated with cardiovascular disease, potentially through atherosclerosis promotion. Few studies have assessed associations of these exposures with thoracic aortic calcium Agatston score (TAC) or abdominal aortic calcium Agatston score (AAC), systemic atherosclerosis correlates. We assessed whether living close to a major road and residential fine particulate matter (PM2.5) exposure were associated with TAC and AAC in a Northeastern US cohort. Design: Cohort study. Setting: Framingham Offspring and Third Generation participants residing in the Northeastern USA. Participants and outcome measures Among 3506 participants, mean age was 55.8 years; 50% female. TAC was measured from 2002 to 2005 and AAC up to two times (2002–2005; 2008–2011) among participants from the Framingham Offspring or Third Generation cohorts. We first assessed associations with detectable TAC (logistic regression) and AAC (generalised estimating equation regression, logit link). As aortic calcium scores were right skewed, we used linear regression models and mixed-effects models to assess associations with natural log-transformed TAC and AAC, respectively, among participants with detectable aortic calcium. We also assessed associations with AAC progression. Models were adjusted for demographic variables, socioeconomic position indicators and time. Results: There were no consistent associations of major roadway proximity or PM2.5 with the presence or extent of TAC or AAC, or with AAC progression. Some estimates were in the opposite direction than expected. Conclusions: In this cohort from a region with relatively low levels of and variation in PM2.5, there were no strong associations of proximity to a major road or PM2.5 with the presence or extent of aortic calcification, or with AAC progression.

Published
2017
Full Text
View/download PDF

45. Abstract 10248: Change in Ankle Brachial Index and Subsequent Risk of Heart Failure and Atrial Fibrillation in Patients With Chronic Kidney Disease

Author

Dorans, Kirsten S, Chen, Jing, Anderson, Amanda H, Mills, Katherine T, Bansal, Nisha, Go, Alan S, Jaar, Bernard G, Kansal, Mayank M, Mehta, Rupal C, Rahman, Mahboob, Rao, Panduranga, Rincon-Choles, Hernan, Rosas, Sylvia E, Weir, Matthew R, and He, Jiang

Abstract

Introduction:Both low and high ankle brachial index (ABI) are associated with cardiovascular disease (CVD) in the general population and among patients with chronic kidney disease (CKD). In small studies of individuals with hemodialysis, decrease in ABI over time has been associated with increased risk of CVD. Given that ABI is a simple, inexpensive, and noninvasive measure of subclinical peripheral arterial disease (PAD) and that individuals with CKD are at increased risk of PAD, heart failure (HF) and atrial fibrillation (AF), it is important to better understand how changes in ABI over time are related to risk of HF and AF in this population.Methods:We carried out a prospective study of 2973 participants with CKD in the Chronic Renal Insufficiency Cohort (CRIC) Study without clinical PAD at baseline. Participants had ABI measured at baseline and second CRIC visit, up to a total of 12 ABI measurements (median 8) at annual study visits. ABI was obtained by standard protocol. Cox proportional hazards regression was used to study the association of annual average change in ABI with risk of HF and AF. The shapes of the relationship of average change in ABI per year with multivariable-adjusted hazards of each outcome were assessed using restricted cubic splines; these shapes were used to choose average annual change in ABI cut-points.Results:We found a U-shaped association of average annual change in ABI with HF (pfor non-linearity = 0.04) and a linear association of average annual change in ABI with AF (pfor linear association = 0.01). Compared with participants with average annual change in ABI of 0 to <0.02, individuals with average annual change in ABI <-0.02, -0.02 to <0, or ?0.02 had multivariable-adjusted hazard ratios (95% CI) of 1.75 (1.25, 2.46), 1.29 (0.98, 1.69), and 1.46 (1.13, 1.88) for HF and 1.39 (0.94, 2.05), 1.24 (0.92, 1.67), and 1.80 (1.40, 2.32) for AF, respectively.Conclusions:This study indicates that higher average annual changes in ABI (positive or negative) were associated with higher risk of HF and that positive average annual changes in ABI were associated with higher risk of AF. These findings suggest that monitoring changes in ABI over time may facilitate risk stratification for subsequent HF and AF among individuals with CKD.

Published
2019
Full Text
View/download PDF

47. trans-Bis(2-amino­phen­yl)diazene.

Author

Bohle, D. Scott, Dorans, Kirsten S., and Fotie, Jean

Subjects
*AZO compounds, *CRYSTALLOGRAPHY, *CHEMICAL bonds, *MOLECULAR structure, *NITROGEN, *ISOMERISM
Abstract

The title compound, C12H12N4, is a trans-azobenzene which crystallizes with an inversion center at the midpoint of the N=N bond. [ABSTRACT FROM AUTHOR]

Published
2007
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results