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Your search keyword '"Dimitropoulos, I"' showing total 22 results
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22 results on '"Dimitropoulos, I"'

1. Flares from plasmoids and current sheets around Sgr A*

Author

Dimitropoulos, I., Nathanail, A., Petropoulou, M., Contopoulos, I., and Fromm, C. M.

Subjects
Astrophysics - High Energy Astrophysical Phenomena
Abstract

The supermassive black hole Sgr A* at the center of our galaxy produces repeating near-infrared flares that are observed by ground and space based instruments. This activity has been simulated in the past with Magnetically Arrested Disk (MAD) models which include stable jet formations. The present study uses a different approach in that it considers a Standard and Normal Evolution (SANE) multi-loop model that lacks a stable jet structure. The main objective of this research is to identify regions that contain current sheets and high magnetic turbulence, and to subsequently generate a 2.2 micron light curve generated from non-thermal particles. Additionally, we investigate the properties of the flares, in particular, their evolution during flare events, and the similarity of flare characteristics between the generated and observed light curves. 2D GRMHD simulation data from a SANE multi-loop model is employed, and thermal radiation is introduced to generate a 230 GHz light curve. Physical variables are calibrated to align with the 230 GHz observations. Current sheets are identified by analyzing toroidal currents, magnetization, plasma beta, density, and dimensionless temperatures. The evolution of current sheets during flare events is studied, and higher-energy non-thermal light curves are calculated, focusing on the 2.2 micron near-infrared range. We obtain promising 2.2 micron light curves whose flare duration and spectral index behavior align well with observations. Our findings support the association of flares with particle acceleration and nonthermal emission in current sheet plasmoid chains and in the boundary of the disk inside the funnel above and below the central black hole., Comment: 12 pages, 15 figures, submitted to Astronomy & Astrophysics

Published
2024

2. A global study of $^9$Be + p at 2.72 A MeV

Author

Soukeras, V., Sgouros, O., Pakou, A., Cappuzzello, F., Casal, J., Agodi, C., Brischetto, G. A., Calabrese, S., Carbone, D., Cavallaro, M., Ciraldo, I., Dimitropoulos, I., Koulouris, S., La Fauci, L., Martel, I., Rodríguez-Gallardo, M., Sánchez-Benítez, A. M., Souliotis, G., Spatafora, A., and Torresi, D.

Subjects
Nuclear Experiment
Abstract

Background: In our recent experiment, $^9$Be+p at 5.67A MeV, the breakup decay rates to the 3 configurations, $\alpha$+$\alpha$+n, $^8$Be$^*$+n and $^5$He+$^4$He of $^9$Be, were observed and quantified, in a full kinematics approach. Unfolding step by step the accessibility to the above configurations, it will require similar studies at lower and higher energies as well as the interpretation of the data in a theoretical framework. Purpose: Investigate the breakup decay rate of $^9$Be+p at 2.72A MeV, where the $\alpha$+$\alpha$+n configuration is mainly accessible. Compare and interpret data at 2.72A MeV and 5.67A MeV into a 4-body CDCC formalism; Point out and discuss couplings to continuum. Methods: Our experimental method includes an exclusive breakup measurement in a full kinematic approach of $^9$Be incident on a proton target at 2.72A MeV, together with elastic scattering and other reaction channels measurements under the same experimental conditions. The interpretation of the data at 2.72A MeV and 5.67A MeV is considered in a 4-body CDCC approach, using the Transformed Harmonic Oscillator method for the 3-body projectile. Results: An elastic scattering angular distribution at 2.72A MeV is measured, which compares very well with CDCC calculations, indicating a strong coupling to continuum. At the same energy, the measured breakup and total reaction cross sections present good agreement with the calculated values. Further on, the elastic scattering and breakup cross section data at 5.67A MeV are found in very good agreement with the CDCC calculations. The present results support further our 3-body model for the structure of $^9$Be, validating relevant radiative reaction rates obtained previously., Comment: 10 pages, 11 figures

Published
2021
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3. Momentum Distributions of Projectile Fragments from Heavy-ion Peripheral Collisions at 15 MeV/nucleon with Emphasis on Trans-Projectile Isotopes

Author

Koulouris, S., Souliotis, G. A., Dimitropoulos, I., Fasoula, O., Palli, K., Veselsky, M., and Bonasera, A.

Subjects
Nuclear Experiment, Nuclear Theory
Abstract

This paper presents our recent efforts to study the momentum distributions as well as the production of neutron-rich rare isotopes with heavy-ion beams in the energy region of 15 MeV/nucleon. Experimental cross sections of neutron-rich nuclides from collisions of a 86 Kr (15 MeV/nucleon) beam with 64 Ni and 58 Ni targets are presented. Experimental data were obtained from the previous work of our group with the MARS mass spectrometer at the Cyclotron Institute of Texas A&M University. On that note, detailed calculations of yields and momentum distributions of neutron-rich projectile-like fragments are presented for the interaction of 86 Kr with 64 Ni and compared with the aforementioned experimental data. The calculations were based on a two-step general approach: the dynamical stage of the primary interaction was described with the phenomenological deep-inelastic transfer model (DIT) and the microscopic constrained molecular dynamics model (CoMD); the deexcitation stage of the excited projectile fragments was described with the statistical binary-decay model GEMINI. The experimental data show an enhancement in the production of neutron-rich isotopes close to the projectile, and interestingly of heavier than the projectile neutron-rich nuclei. The behaviour of the data is relative to the predictions of the CoMD/GEMINI calculation. The study of the momentum distributions offers a novel route to study the reaction mechanism that dominates the production of the fragments of interest in peripheral heavy-ion collisions at intermediate energies. In the future, we plan to analyze experimental data that were obtained from the MAGNEX spectometer at the INFN-LNS in Catania, Italy.

Published
2021

5. Microscopic dynamical description of multinucleon transfer in 40Ar induced peripheral collisions at 15 MeV/nucleon

Author

Palli K., Souliotis G. A., Depastas T., Dimitropoulos I., Fasoula O., Koulouris S., Veselsky M., Yennello S. J., and Bonasera A.

Subjects
Physics, QC1-999
Abstract

This paper deals with heavy-ion peripheral reactions in the Fermi energy region for the production of neutron-rich isotopes. Experimental data of projectile fragments from the reactions of an 40Ar beam at 15 MeV/nucleon with 64Ni and 58Ni targets, collected with the MARS spectrometer at the Cyclotron Institute of Texas A&M University, are considered. Momentum distributions, which provide valuable information on the reaction mechanisms, are extracted and compared with two types of calculations: These are, the Deep Inelastic Transfer (DIT) model and the microscopic Constrained Molecular Dynamics model (CoMD). For the latter, the parameters of the original code were systematically varied in order to achieve an overall satisfactory description of the experimental data. Our results will be discussed.

Published
2021
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6. Routine Tracheal Intubation and Meconium Suctioning in Non-Vigorous Neonates with Meconium-Stained Amniotic Fluid: A Systematic Review and Meta-Analysis

Author

Dikou, M. Xanthos, T. Dimitropoulos, I. Iliodromiti, Z. Sokou, R. Kafalidis, G. Boutsikou, T. Iacovidou, N.

Abstract

The aim of this systematic review and meta-analysis is the comparison of endotracheal intubation and suctioning to immediate resuscitation without intubation of non-vigorous infants > 34 weeks’ gestation delivered through meconium-stained amniotic fluid (MSAF). Randomized, non-randomized clinical trials and observational studies were included. Data sources were PubMed/Medline and Cochrane Central Registry of Controlled Trials, from 2012 to 2021. Inclusion criteria were non-vigorous infants born through MSAF with gestational age > 34 weeks and sample size ≥ 5. We calculated overall relative risks (RR) and mean differences (MD) with a 95% confidence interval (CI) to determine the impact of endotracheal suction (ETS) in non-vigorous infants born through MSAF. The outcomes presented are the incidence of neonatal mortality, meconium aspiration syndrome (MAS), transient tachypnea, need for positive pressure ventilation, respiratory support, persistent pulmonary hypertension treatment, neonatal infection, ischemic encephalopathy, admission to neonatal intensive care unit (NICU) and the duration of hospitalization between ETS and non-ETS group. Six studies with a total sample of 1026 patients fulfilled the inclusion criteria. Statistically non-significant difference was observed in RR between two groups with regards to mortality (1.22, 95% CI 0.73–2.04), occurrence of MAS (1.08, 95% CI 0.76–1.53) and other outcomes, and MD in hospitalization duration. There is no sufficient evidence to suggest initiating endotracheal suction soon after birth in non-vigorous meconium-stained infants as routine. © 2022 by the authors. Licensee MDPI, Basel, Switzerland.

Published
2022

7. The effect of treatment with recombinant human growth hormone (rhGH) on linear growth and adult height in children with idiopathic short stature (ISS): A systematic review and meta-analysis

Author

Paltoglou, G. Dimitropoulos, I. Kourlaba, G. Charmandari, E.

Abstract

Objectives: Idiopathic short stature (ISS) is a recognized, albeit a controversial indication for treatment with recombinant human growth hormone (rhGH). The objective of the present study was to conduct a systematic review of the literature and meta-analyses of selected studies about the use of rhGH in children with ISS on linear growth and adult height (AH). Methods: A systematic literature search was conducted to identify relevant studies published till February 28, 2017 in the following databases: Medline (PubMed), Scopus and Cochrane Central Registry of Controlled Trials. After exclusion of duplicate studies, 3,609 studies were initially identified. Of those, 3,497 studies were excluded during the process of assessing the title and/or the abstract. The remaining 112 studies were evaluated further by assessing the full text; 21 of them fulfilled all the criteria in order to be included in the current meta-analysis. Results: Children who received rhGH had significantly higher height increment at the end of the first year, an effect that persisted in the second year of treatment and achieved significantly higher AH than the control group. The difference between the two groups was equal to 5.3 cm (95% CI: 3.4–7 cm) for male and 4.7 cm (95% CI: 3.1–6.3 cm) for female patients. Conclusion: In children with ISS, treatment with rhGH improves short-term linear growth and increases AH compared with control subjects. However, the final decision should be made on an individual basis, following detailed diagnostic evaluation and careful consideration of both risks and benefits of rhGH administration. © 2020 De Gruyter. All rights reserved.

Published
2020

8. Global study of Be 9 + p at 2.72A MeV GLOBAL STUDY of BE 9 +p at 2.72A MEV V. SOUKERAS et al

Author

Soukeras, V. Sgouros, O. Pakou, A. Cappuzzello, F. Casal, J. Agodi, C. Brischetto, G.A. Calabrese, S. Carbone, D. Cavallaro, M. Ciraldo, I. Dimitropoulos, I. Koulouris, S. La Fauci, L. Martel, I. Rodríguez-Gallardo, M. Sánchez-Benítez, A.M. Souliotis, G. Spatafora, A. Torresi, D.

Subjects
Nuclear Experiment
Abstract

Background: In our recent experiment, Be9+p at 5.67A MeV, the breakup decay rates to the three configurations, α+α+n, Be∗8+n and He5+He4 of Be9, were observed and quantified in the proton recoil spectra, in a full kinematics approach. Unfolding step by step the accessibility to the above configurations, it will require similar experiments at lower or/and higher energies. It will also require the interpretation of the data in a theoretical framework. Three-body models for the structure of Be9 have been developed and applied to reactions with heavy targets. Further research on lighter targets is required for the best establishment of the model. Such models are relevant for the calculation of the corresponding radiative capture reaction rate, α(α,γ)Be9 followed by Be9(α,n)C12. The last is essential for the r-process abundance predictions. Purpose: Investigate the breakup decay rate of Be9+p at 2.72A MeV, where the direct configuration α+α+n is mainly accessible. Compare and interpret data at this low energy and at the higher energy of 5.67A MeV into a four-body continuum discretized coupled-channel formalism. Point out and discuss couplings to continuum. Methods: Our experimental method includes an exclusive breakup measurement in a full kinematic approach of Be9 incident on a proton target at 24.5 MeV (2.72A MeV). Complementary the elastic scattering is measured and other reaction channels are evaluated from previous measurements under the same experimental conditions. The interpretation of present data at 2.72A MeV and previous data at 5.67A MeV, are considered in a four-body continuum discretized coupled channel (CDCC) approach, using the transformed harmonic oscillator method for the three-body projectile. Results: An elastic scattering angular distribution at 2.72A MeV is measured, which compares very well with CDCC calculations, indicating a strong coupling to continuum. At the same energy, the breakup and total reaction cross sections are measured as σbreak=2.5±1mb and σtot=510±L90mb, in good agreement with the calculated values of 3.7 and 433 mb, respectively. Further on, into the same theoretical framework, the elastic scattering and breakup cross section data at 5.67A MeV are found in very good agreement with the CDCC calculations. Conclusions: It was confirmed in a global experimental framework that four-body CDCC calculations can describe very well the data even at low energies. Coupling to continuum is very strong despite the small measured breakup cross section. Moreover, the present results support further our three-body model for the structure of Be9, validating relevant radiative reaction rates obtained previously. © 2020 American Physical Society.

Published
2020

10. Global study of Be9 + p at 2.72A MeV

Author

Soukeras, V., primary, Sgouros, O., additional, Pakou, A., additional, Cappuzzello, F., additional, Casal, J., additional, Agodi, C., additional, Brischetto, G. A., additional, Calabrese, S., additional, Carbone, D., additional, Cavallaro, M., additional, Ciraldo, I., additional, Dimitropoulos, I., additional, Koulouris, S., additional, La Fauci, L., additional, Martel, I., additional, Rodríguez-Gallardo, M., additional, Sánchez-Benítez, A. M., additional, Souliotis, G., additional, Spatafora, A., additional, and Torresi, D., additional

Published
2020
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11. Microscopic dynamical description of multinucleon transfer in 40Ar induced peripheral collisions at 15 MeV/nucleon.

Author

Palli, K., Souliotis, G. A., Depastas, T., Dimitropoulos, I., Fasoula, O., Koulouris, S., Veselsky, M., Yennello, S. J., and Bonasera, A.

Subjects
COLLISIONS (Nuclear physics), HEAVY ions, MOMENTUM distributions, DEEP inelastic collisions, SPECTROMETERS
Abstract

This paper deals with heavy-ion peripheral reactions in the Fermi energy region for the production of neutron-rich isotopes. Experimental data of projectile fragments from the reactions of an 40Ar beam at 15 MeV/nucleon with 64Ni and 58Ni targets, collected with the MARS spectrometer at the Cyclotron Institute of Texas A&M University, are considered. Momentum distributions, which provide valuable information on the reaction mechanisms, are extracted and compared with two types of calculations: These are, the Deep Inelastic Transfer (DIT) model and the microscopic Constrained Molecular Dynamics model (CoMD). For the latter, the parameters of the original code were systematically varied in order to achieve an overall satisfactory description of the experimental data. Our results will be discussed. [ABSTRACT FROM AUTHOR]

Published
2021
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12. Promoting Undergraduate Surgical Education: Current Evidence and Students’ Views on ESMSC International Wet Lab Course

Author

Sideris, M. Papalois, A. Theodoraki, K. Dimitropoulos, I. Johnson, E.O. Georgopoulou, E.-M. Staikoglou, N. Paparoidamis, G. Pantelidis, P. Tsagkaraki, I. Karamaroudis, S. Potoupnis, M.E. Tsiridis, E. Dedeilias, P. Papagrigoriadis, S. Papalois, V. Zografos, G. Triantafyllou, A. Tsoulfas, G.

Subjects
education
Abstract

Background: Undergraduate Surgical Education is becoming an essential element in the training of the future generation of safe and efficient surgeons. Essential Skills in the Management of Surgical Cases (ESMSC), is an international, joint applied surgical science and simulation-based learning wet lab course. Methods: We performed a review of the existing literature on the topic of undergraduate surgical education. Following that, we analyzed the feedback questionnaire received 480 from 2 recent series of ESMSC courses (May 2015, n = 49 and November 2015, n = 40), in order to evaluate European Union students' (UK, Germany, Greece) views on the ESMSC course, as well as on the undergraduate surgical education. Results Using a 10 point graded scale, the overall ESMSC concept was positively evaluated, with a mean score of 9.41 ± 0.72 (range: 8–10) and 8.94 ± 1.1 (range: 7–10). The majority of delegates from both series [9.86 ± 0.43 (range: 8–10) and 9.58 ± 0.91 (range: 6–10), respectively] believed that ESMSC should be incorporated in the undergraduate surgical curriculum. Comparison of responses from the UK to the Greek Medical Student, as well as the findings from the third and fourth year versus the fifth and sixth year Medical Students, revealed no statistically significant differences pertaining to any of the questions (p > 0.05). Conclusions: Current evidence in the literature supports the enhancement of surgical education through the systematic use of various modalities that provide Simulation-Based Training (SBT) hands-on experience, starting from the early undergraduate level. The findings of the present study are in agreement with these previous reports. Copyright © 2017 Taylor & Francis Group, LLC.

Published
2017

13. Effects of once-weekly exenatide on cardiovascular outcomes in type 2 diabetes

Author

Holman, Rr, Bethel, Ma, Mentz, Rj, Thompson, Vp, Lokhnygina, Y, Buse, Jb, Chan, Jc, Choi, J, Gustavson, Sm, Iqbal, N, Maggioni, Ap, Marso, Sp, Öhman, P, Pagidipati, Nj, Poulter, N, Ramachandran, A, Zinman, B, Hernandez, Af, EXSCEL Study Group, : Califf RM, Patel, R, George, J, Sourij, H, Wong, Yw, Hannan, K, Sellers, Ma, Gottlieb, P, Lavender, P, Leloudis, D, Meadows, Y, Larson, D, Anderson, H, Elkins, M, Stone, A, Tisch, A, Perkins, L, Sanders, K, Campbell, C, Kennedy, I, Heal, P, Masterson, M, Darbyshire, J, Mumtaz, L, Athwal, R, Ferch, A, Batra, P, Durborow, L, Vincent, J, Woodall, A, Flanagan, T, Katona, B, Reicher, B, Pozzi, E, Oulhaj, A, Coleman, R, Rouleau, Jl, Pocock, Sj, Gorelick, F, Mcmurray, J, Riddle, M, Gagel, R, Collier, T, Markovic, T, Kong, Aps, Hian, Sk, Scott, R, Panelo, A, Yoon, Kh, Sheu, W, Sritara, P, Linong, J, Pan, C, Yong, H, Schernthaner, G, Mathieu, C, Tankova, T, Widimsky, P, Hanefeld, M, Keltai, M, Wainstein, J, del Prato, S, Pirags, V, Jakuboniene, N, Kooy, A, Dziemidok, P, Veresiu, Ia, Dreval, Av, Murin, J, Torello, Al, Sattar, N, Parkhomenko, O, Omar, M, Diaz, R, Lopes, R, Lanas, F, Urina Triana, M, Leiva-Pons, Jl, Aguliera, D, Bergenstal, R, Goodman, S, Yale, Jf, Caterson, I, Weng, J, Hu, D, Junbo, G, Zannad, F, Anoop, M, Ambrish, M, Gallegos, Ja, Green, Jb, Akerblom, A, Alexander, K, Al-Khatib, S, Armaganijan, L, Barros, P, Batit, M, Bernacki, G, Bernandez, S, Bloomfield, G, Clausen, E, De Souza Brito, F, Devore, A, Dombrowski, K, Eapen, Z, Gellad, Z, George, D, Guimaraes, P, Halim, S, Harrison, R, Hawes, J, Hess, C, Hyland, K, Jackson, L, Jones, S, Jordan, D, Katz, M, Kong, D, Koshizaka, M, Lakey, W, Leblanc, T, Leonardi, S, Luo, N, Mahaffey, K, Mandawat, A, Mehta, R, Melloni, C, Morse, M, Pagidpati, N, Patel, C, Patel, K, Pokorney, S, Posvic, T, Rao, M, Roe, M, Shah, B, Tillmann, H, Truffa, A, Zazula, A, Zeitler, E, Sicer, M, Ulla, Mr, Maffei, L, Klyver, Mi, Calella, P, Alvarisqueta, A, De La Fuente RL, Aizenberg, D, Roque, F, Cruciani, A, Frechtel, G, Gelersztein, E, Villarino, A, Mallagray, M, Nardone, L, Zaidman, C, Novaretto, L, Bartolacci, I, de Salvo, M, Delcourt, C, Crimmins, D, Jackson, R, O’Neal, D, Colman, P, Jeffries, W, Mah, Pm, Wittert, G, Proietto, J, Amerena, J, Marks, S, Tan, R, Colquhoun, D, Pieber, T, Drexel, H, Prager, R, Schnack, C, Hoppichler, F, Fasching, P, Francesconi, C, Luger, A, Schoenherr, Hr, Ebenbichler, C, Paulweber, B, Shernthaner, G, Verhaegen, A, Vanuytsel, J, Thissen, Jp, e Silva P, Barros, Gonzaga, C, Borges, J, Hissa, M, Rea, R, Rossi, P, Chacra, A, Eliaschewitz, F, Garbelini, B, Felicio, J, Rassi, N, Rossi, F, Nunes dos Santos, M, e Farias F, Bandeira, Lisboa, H, e Forti A, Costa, Saraiva, Jk, Kovacheva, S, Levterov, G, Sheinkova, G, Ilieva, E, Lyubenova, L, Damyanova, V, Gushterova, V, Mincheva, L, Illiev, D, Ivanov, V, Bobeva, R, Nikitov, Z, Shumkova, R, Lefterov, In, Zaharieva, S, Videva, V, Yakov, A, Cheung, S, Elliott, T, Mehta, P, Ross, S, Sigal, R, Woo, V, Jaffer, S, Kuritsky, R, Bell, A, Dumas, R, Gosselin, G, Robitaille, Y, Greenspoon, A, Lochnan, H, Tytus, R, Leiter, L, Pandey, A, Punthakee, Z, Dube, F, Sigalas, J, Pearce, M, Woodford, T, Paul, P, Bourgeois, R, Conway, R, Mazza, G, Hatheway, R, Misterski, J, Raffo, C, Olivares, C, Godoy, J, Potthoff, S, Santibañez, C, Larenas Yanez GJ, Gu, W, Shen, F, Ma, J, Guo, X, Li, Q, Du, Y, Hu, J, Ji, L, Li, Y, Deng, H, Feng, Y, Liu, L, Mu, Y, Ma, C, Qu, S, Wang, J, Wang, Y, Yuan, Z, Zhang, L, Zhou, S, Yang, T, Dong, Y, Liu, D, Coronel Arroyo, J, Perez Amador, G, Botero Lopes, R, Jaramilo, C, Orozco Linares, A, Cure Cure CA, Hernandez Triana, E, Molina de Salazar DI, Marin, Cr, Jaramilo Gomez CJ, Kellinerova, I, Adamkova, V, Krami, P, Brychta, T, Havelkova, J, Pantikova, K, Schoper, F, Pohl, W, Schumm-Draeger, Pm, Julius, U, Tschöpe, D, Hamann, A, Seissler, J, Schellong, S, Rose, L, Becker, B, Linn, T, Oerter, Em, Strotmann, Hj, Mölle, A, Pfutzner, A, Forst, T, Schäufele, T, Mugge, A, Lehrke, M, Meyer-Pannwitt, U, Mehling, H, Simon-Wagner, I, Schenkenberger, I, Busch, K, Hermes, S, Milek, K, Landers, B, Grueneberg, M, Braun, M, Nothroff, J, Kamke, W, Hergdt, G, Duengen, Hd, Kleinertz, K, Kuesters, D, Boenninghoff, Ah, Appel, Kf, Schaefer, A, Bieler, T, Ozaki, R, Luk, Aoy, Chu, Dw, Cheung-Wong, Mm, Siu, Dc, Yan, Bpy, Kung, K, Wong, Sys, Tsang, Cc, Yeung, Vt, Cheung, Bm, Tse, Hf, Hodi, G, Nagy, K, Lippai, J, Takacs, J, Fulop, T, Gaal, Z, Pauker, Z, Foldesi, I, Simon, J, Oroszan, T, Futo, L, Bezzegh, K, Nagy, A, Vandorfi, G, Kiss, J, Kesmarki, N, Kis, E, Papp, A, Kovacs, A, Szakal, I, Palinkas, A, Czegany, Z, Voros, P, Reiber, I, Kerenyi, Z, Dezso, E, Wittman, I, Penzes, J, Ples, Z, Taller, A, Farago, K, Kis, Jt, Zilahi, Z, Molnar, M, Barkai, L, Mileder, M, Szentpeteri, I, Peterfai, E, Lovasz, O, Mosenzon, O, Minuchin, O, Jaffe, A, Vishlitsky, V, Shimon, I, Bashkin, A, Stern, N, Elias, N, Bental, T, Butnaru, A, Lewis, B, Adawi, F, Nseir, W, Klainman, E, Herskovits, T, Cignarelli, M, Rotella, Cm, Ambrosio, G, Pozzilli, P, Genovese, S, Cavarape, A, Salvioni, A, Sokolova, J, Strautina, I, Teterovska, D, Stalte, V, Pastare, S, Leitane, I, Lagzdina, L, Andersone, I, Eglite, R, Stelmane, I, Levinger, A, Barsiene, L, Sulskiene, M, Varanauskiene, E, Danyte, E, Urbanaviciene, E, Urbanavicius, V, Zabuliene, L, Juskiene, R, Velaviciene, A, Kakariekiene, V, Augusteniene, A, Velickiene, D, Lasiene, J, Dauksiene, D, Caponis, J, Tan, At, Ramanathan, L, Hassan, Mra, Tan, F, Ong, Tk, Foo, Sh, Ghani, Ra, Cheah, Wk, Sanchez Mijangos JH, Cabrera Jardines, R, Barrientos Perez, M, Sauque Reyna, L, Alcocer Gamba MA, Villeda Espinosa, E, Tamez Perez HE, De La Garza Hernandez NE, Lopes, Sm, Ramirez Diaz SP, Reyes Sanchez, R, Márquez-Rodriguez, E, Köse, V, Voors-Pette, C, Oldenburg-Ligtenberg, Pc, van Kempen WW, Cox, K, Hoogendyk, J, Swinkels-Diepenmaat, L, Rojas-Lingan, G, Kentgens, S, Schipperen, S, de Valk HW, Swart, H, van Bemmel, B, Hoogslag, Pam, Diamant, M, Serné, Eh, Hamer, A, Wilson, S, Fisher, N, Dixon, P, Chaudhri, O, Crawford, V, Quinn, D, Nirmalaraj, K, Dunn, P, Gillies, J, Cutfield, R, Krebs, J, Helm, C, Kerr, J, Pryke, J, Ebo, G, Denopol, M, Ang, E, Uy, N, Jimeno, C, Mirasoi, R, Paz Pacheco, E, Custodio, M, Nicodemus, N Jr, Catindig, Ea, Magno, M, Tirador, L, Cylkowska, B, Stasinksa, T, Silwinska, T, Sroka, M, Piepiorka, M, Korzeniak, R, Mirecka, H, Zaluska, R, Pupek-Musialik, D, Homenda, W, Grabowska, A, Okopien, B, Niegowska, J, Pogorzelska, H, Mikolajczyk-Swatko, A, Sikorski, M, Sowinski, D, Tahk, Sj, Kim, Yn, Nam, Cw, Rim, Sj, Kim, Cj, Choi, Km, Lee, Ik, Kim, Ij, Namgung, J, Moon, Kw, Kim, Ks, Oh, Bh, Lee, Wy, Choi, Sh, Kim, Es, Moon, S, Mindrescu, Nm, Aron, G, Graur, M, Hancu, N, Mlitaru, C, Nafornita, V, Szilagyi, I, Popa, Ar, Angelescu, Lm, Negrisanu, Gd, Zaharie, Dg, Culman, Mi, Vacaru, G, Munteanu, M, Constantinescu, S, Tivadar, S, Dreval, A, Barbarash, O, Strongin, L, Dogadin, S, Suplotova, L, Izmozherova, N, Marasaev, V, Khokhlov, A, Repin, A, Turova, E, Bondar, I, Samoylova, Y, Sherenkov, A, Smolenskaya, O, Zrahevskiy, K, Koshelskaya, O, Obrezan, A, Dzupina, A, Stevlik, J, Buganova, I, Pella, D, Vinanska, D, Jascur, J, Micko, K, Sosovec, D, Philippiova, A, Olexa, P, Fedacko, J, Selecky, J, Nicolau, J, Mediavilla Garcia, J, Botella Serrano, M, Lecube, A, Arguelles, I, Sabán, J, Gómez Cerezo, F, Soto, A, Bellido, D, Sucunza Alfonso, N, Vendrell Ortega, J, Alvarez, L, Garcia Puig, J, Angustias Quesada, M, Contreras Gilbert, J, Almeida, Ca, Tinahones, Fj, Garcia Ortiz, L, Gómez Marcos MA, Aomar, I, Fernández Balsells, M, Distiller, L, Padayachee, T, Badat, A, Ebrahim, I, Naiker, P, Ranjith, N, Kelfkens, Y, Makan, H, Mogashoa, S, Fulat, M, Carim-Ganey, N, Coetzee, K, Govender, T, Nortje, H, Wilhase, A, Seedat, S, Gani, M, Ellis, G, Rheeder, P, Wing, J, Blignaut, S, Kaplan, H, Lottering, H, Pillai, P, Louw, C, Coetzer, T, Sheu, Whh, Chen, Jf, Yang, Cy, Tseng, St, Wang, Cy, Lai, Wt, Hung, Yj, Hsieh, Ic, Su, Sl, Pei, D, Benjasuratwong, Y, Purewal, T, Milward, A, Dimitropoulos, I, Kumar, S, Barber, T, Wiles, P, Dang, C, Adler, A, Philip, S, Bellary, S, Price, D, Oelbaum, R, Heller, S, Sathayapalan, T, Clark, J, Leese, G, Simpson, H, Kilvert, A, Dawson, A, Hall, T, Takhar, A, Bundy, C, Harvey, P, Maxwell, S, Asamoah-Owusu, Nj, Mcknight, J, Chatterjee, S, Calvert, J, Wright, A, Macrury, S, Macfarlane, D, Johnson, A, Litchfield, J, Field, B, Koval, O, Larin, O, Levchenko, O, Martynyuk, L, Maslyanko, V, Rudyk, I, Suprun, Y, Tseluyko, V, Botsyurko, V, Vatutin, M, Fushtey, I, Grishyna, O, Kuskalo, P, Panina, S, Pererva, L, Prysupa, L, Teliatnikova, Z, Sokolova, L, Vlasenko, M, Berenfus, V, Gyrina, O, Kopytsya, M, Vizir, V, Vayda, M, Shanik, M, Headapohl, D, Pahl, J, Aronoff, S, Bartkowiak, A Jr, Chang, A, Gaudiani, L, Kayne, D, Look, M, Patel, N, Moran, J, Stout, E, Tsao, J, Struble, R, Fishman, N, Rodbard, H, Lucas, K, Dugano-Daphnis, P, Merrick, B, Nadar, V, Severa, L, Sorli, C, Chang, M, Reed, J III, Grunberger, G, Bain, C, Bestermann, W Jr, Morawski, E, White, J, Azizad, M, Ukwade, P, Anekwe, A, Jimenez, A, Weiss, D, Green, S, Overcash, J, Eaton, C, Roseman, H, Soler, N, Mikell, F, Manos, P, Levinson, L, Claxton, E Jr, Weiss, R, Argoud, G, Bickel, L, Wilson, J, Short, B, Webster, B, Mcneill, R, Schnall, A, Force, R, Phillips, L, Bybee, K, Forker, A, Denham, D, Vonderhaar, T, Pullman, J, Kruger, D, Whitehouse, F, Wysham, C, Baron, M, Kravitz, A, Dushkin, H, Manning, Mb, Wine, A, Jaffrani, N, Chadha, C, Sperl-Hillen, J, Busch, R, Estevez, R, Robbins, D, Rassouli, N, Garvey, T, Oparil, S, Eckel, R, Mcdermott, M, Rasouli, N, Mcgill, J, Corder, C, Klonoff, D, Mills, R, Earl, J, Kessel, J, Cuddihy, R, Zimmerman, R, Dayamani, P, Oral, E, Zimering, M, Marks, J, Farnsworth, K, Sugimoto, D, Toth, P, Bhargava, A, Mcguire, D, Rohatgi, A, Davies, M, Peden, E, Wyne, K, Alfonso, L, Seyoum, B, Akpunonu, B, Feinglos, M, Reaven, P, Soule, J, Luttrell, L, Schactman, B, Canadas, R, Boggs, B, Abbott, L, Herring, C, Roberts, L, Hage-Korban, E, Schubart, U, Taylon, A, Tannenbaum, A, Kingsley, J, Lenhard, J, Biscoveanu, M, Cohen, J, Donovan, D, Laferrere, B, Thompson, N, Wade, T, Detweiler, R, Henson, B, White, A, Cavale, A, Ravi, C, Thomas, A, Goodman, H, Kalen, V, Fox, D, Dauber, I, Rizvi, S, Marcus, A, Mulford, M, Higgins, A, Chane, M, Bland, V, Osunkoya, A, Suresh, D, Khan, S, Anastasi, L, Bajaj, M, Eisen, H, Mudaliar, Sr, Powell, S, Carr, K, Tripathy, D, Azad, N, Wakefield, P, Acheatel, R, Bressler, P, Dean, J, El Shahawy, M, Gilbert, J, Haque, I, Humiston, D, Ison, R, Karounos, D, Lillestol, M, Ferrier, N, Labroo, A, Vo, A, D’Agostino, R, Dulin, M, Mcwilliams, A, Hargrove, J, Blumberg, E, Jackson, B, Staniloae, C, Salacata, A, Hidalgo, H Jr, Nicol, P, Digiovanna, M, Soufer, J, Mahabadi, V, Akinboboye, O, Arauz-Pacheco, C, Neutel, J, Dungan, K, Benson, M, Powell, T, Gandy, W, Rovner, S, Berk, M, Khan, A, Ledesma, G, Madu, I, Erickson, B, Radbill, M, Graves, M, Kaczmarek, G, Giep, S, Baldauf, C, Golden, G, Lesh, K, Davis, C, Godbole, N, Kirby, W, Razzaque, N, Bhatt, B, Wilson, M., Internal medicine, ACS - Diabetes & metabolism, and ACS - Microcirculation

Subjects
Male, medicine.medical_specialty, EXSCEL Study Group, Injections, Subcutaneous, 030209 endocrinology & metabolism, Type 2 diabetes, Kaplan-Meier Estimate, 030204 cardiovascular system & hematology, Placebo, Article, Drug Administration Schedule, GLP1-agonists, 03 medical and health sciences, 0302 clinical medicine, Double-Blind Method, Interquartile range, Internal medicine, Diabetes mellitus, General & Internal Medicine, medicine, Humans, Hypoglycemic Agents, Least-Squares Analysis, Aged, Glycated Hemoglobin, business.industry, Venoms, Semaglutide, Incidence, Type 2 diabetes, GLP1-agonists, exenatide, cardiovascular effects, General Medicine, 11 Medical And Health Sciences, Middle Aged, medicine.disease, Surgery, Albiglutide, Editorial, Diabetes Mellitus, Type 2, Cardiovascular Diseases, Exenatide, Dulaglutide, Female, business, Peptides, cardiovascular effects, medicine.drug
Abstract

BACKGROUND: The cardiovascular effects of adding once-weekly treatment with exenatide to usual care in patients with type 2 diabetes are unknown. METHODS: We randomly assigned patients with type 2 diabetes, with or without previous cardiovascular disease, to receive subcutaneous injections of extended-release exenatide at a dose of 2 mg or matching placebo once weekly. The primary composite outcome was the first occurrence of death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke. The coprimary hypotheses were that exenatide, administered once weekly, would be noninferior to placebo with respect to safety and superior to placebo with respect to efficacy. RESULTS: In all, 14,752 patients (of whom 10,782 [73.1%] had previous cardiovascular disease) were followed for a median of 3.2 years (interquartile range, 2.2 to 4.4). A primary composite outcome event occurred in 839 of 7356 patients (11.4%; 3.7 events per 100 person-years) in the exenatide group and in 905 of 7396 patients (12.2%; 4.0 events per 100 person-years) in the placebo group (hazard ratio, 0.91; 95% confidence interval [CI], 0.83 to 1.00), with the intention-to-treat analysis indicating that exenatide, administered once weekly, was noninferior to placebo with respect to safety (P

Published
2017
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14. Evaluating the educational environment of an international animal model-based wet lab course for undergraduate students

Author

Sideris, M.C. Papalois, A.E. Athanasiou, T. Dimitropoulos, I. Theodoraki, K. Dos Santos, F.S. Paparoidamis, G. Staikoglou, N. Pissas, D. Whitfield, P.C. Rampotas, A. Papagrigoriadis, S. Papalois, V. Zografos, G. Tsoulfas, G.

Subjects
education
Abstract

Background Essential Skills in the management of Surgical Cases – ESMSC is an International Combined Applied Surgical Science and Wet Lab course aimed at the undergraduate level. ESMSC combines interactive basic science workshops and case-based learning, with basic surgical training modules (BST) on Ex Vivo and In Vivo swine model. In Vivo Dissections include more advanced modules i.e. Abdominal Anatomy Dissections and Cardiac Transplant. Aim To evaluate the educational environment of a novel course, as well as to compare Medical students' perceptions across various groups. Materials and Methods 83 Delegates from King's College London (KCL) and several Hellenic Medical Schools attended the ESMSC course. The DREEM inventory was distributed upon completion of the modules. Results The mean overall score for DREEM inventory was 148.05/200(99–196, SD = 17.90). Cronbach's Alpha value was 0.818, indicating good internal consistency of the data. Year 3/4 Students have a significantly positive “Perception of Learning”, when compared to Year 5/6 (36.43 vs. 33.75, p = 0.017). KCL Students have a more positive view of the course compared to their Greek counterparts (155.19 vs. 145.62/200, p = 0.034). No statistical significant difference was noted when comparing male vs. female students (p > 0.05). Conclusions Students seem to positively rate the ESMSC educational environment. Junior as well as KCL students appear to be more enthusiastic. Further research should focus on the optimal strategy for early involvement and motivation of various students' groups in BST. © 2016 The Author(s)

Published
2016

15. Routine Tracheal Intubation and Meconium Suctioning in Non-Vigorous Neonates with Meconium-Stained Amniotic Fluid: A Systematic Review and Meta-Analysis.

Author

Dikou M, Xanthos T, Dimitropoulos I, Iliodromiti Z, Sokou R, Kafalidis G, Boutsikou T, and Iacovidou N

Abstract

The aim of this systematic review and meta-analysis is the comparison of endotracheal intubation and suctioning to immediate resuscitation without intubation of non-vigorous infants > 34 weeks’ gestation delivered through meconium-stained amniotic fluid (MSAF). Randomized, non-randomized clinical trials and observational studies were included. Data sources were PubMed/Medline and Cochrane Central Registry of Controlled Trials, from 2012 to 2021. Inclusion criteria were non-vigorous infants born through MSAF with gestational age > 34 weeks and sample size ≥ 5. We calculated overall relative risks (RR) and mean differences (MD) with a 95% confidence interval (CI) to determine the impact of endotracheal suction (ETS) in non-vigorous infants born through MSAF. The outcomes presented are the incidence of neonatal mortality, meconium aspiration syndrome (MAS), transient tachypnea, need for positive pressure ventilation, respiratory support, persistent pulmonary hypertension treatment, neonatal infection, ischemic encephalopathy, admission to neonatal intensive care unit (NICU) and the duration of hospitalization between ETS and non-ETS group. Six studies with a total sample of 1026 patients fulfilled the inclusion criteria. Statistically non-significant difference was observed in RR between two groups with regards to mortality (1.22, 95% CI 0.73−2.04), occurrence of MAS (1.08, 95% CI 0.76−1.53) and other outcomes, and MD in hospitalization duration. There is no sufficient evidence to suggest initiating endotracheal suction soon after birth in non-vigorous meconium-stained infants as routine.

Published
2022
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16. Pituitary haemorrhage and infarction: the spectrum of disease.

Author

Iqbal F, Adams W, Dimitropoulos I, Muquit S, and Flanagan D

Abstract

Background: Pituitary apoplexy is an acute syndrome of haemorrhage or infarction into the pituitary. The condition is relatively well-described. Less well-described is sub-acute presentation of the same condition., Objective: To compare the clinical presentation and natural history of subacute pituitary haemorrhage/infarction with pituitary apoplexy (acute)., Method: Retrospective analysis of a consecutive cohort of 55 patients (33 with pituitary apoplexy, 22 with subacute disease) presenting to University Hospital Plymouth between 1994 and 2019. Comparison of the clinical, endocrinological and radiological features at presentation. Comparison of clinical treatment and subsequent outcomes for the two groups., Results: There were no significant differences in predisposing factors for the two groups. Acute headache was more frequent in the acute group. Chronic headache was common in both groups prior to presentation. Low sodium was more common at presentation in the acute group (11/26 vs 2/19 P = 0.02) otherwise there were no differences in endocrine deficit at presentation. A significant proportion showed an improvement in endocrine function at follow up (acute 8/31, subacute 5/21 P = 1.0). MRI characteristics were variable at presentation and follow up in both groups. Ring enhancement with contrast was more frequent in acute (14/20 vs 3/11 P = 0.03). This appearance resolved at follow up in the majority., Conclusions: Pituitary apoplexy has a characteristic and dramatic presentation. Subacute pituitary haemorrhage/infarction shows similar natural history and outcome. These conditions would appear to represent a spectrum of the same condition.

Published
2021
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17. The effect of treatment with recombinant human growth hormone (rhGH) on linear growth and adult height in children with idiopathic short stature (ISS): a systematic review and meta-analysis.

Author

Paltoglou G, Dimitropoulos I, Kourlaba G, and Charmandari E

Subjects
Dwarfism pathology, Growth Disorders pathology, Humans, Body Height drug effects, Dwarfism drug therapy, Growth Disorders drug therapy, Human Growth Hormone administration & dosage, Recombinant Proteins administration & dosage
Abstract

Objectives: Idiopathic short stature (ISS) is a recognized, albeit a controversial indication for treatment with recombinant human growth hormone (rhGH).The objective of the present study was to conduct a systematic review of the literature and meta-analyses of selected studies about the use of rhGH in children with ISS on linear growth and adult height (AH)., Methods: A systematic literature search was conducted to identify relevant studies published till February 28, 2017 in the following databases: Medline (PubMed), Scopus and Cochrane Central Registry of Controlled Trials. After exclusion of duplicate studies, 3,609 studies were initially identified. Of those, 3,497 studies were excluded during the process of assessing the title and/or the abstract. The remaining 112 studies were evaluated further by assessing the full text; 21 of them fulfilled all the criteria in order to be included in the current meta-analysis., Results: Children who received rhGH had significantly higher height increment at the end of the first year, an effect that persisted in the second year of treatment and achieved significantly higher AH than the control group. The difference between the two groups was equal to 5.3 cm (95% CI: 3.4-7 cm) for male and 4.7 cm (95% CI: 3.1-6.3 cm) for female patients., Conclusion: In children with ISS, treatment with rhGH improves short-term linear growth and increases AH compared with control subjects. However, the final decision should be made on an individual basis, following detailed diagnostic evaluation and careful consideration of both risks and benefits of rhGH administration., (© 2020 Walter de Gruyter GmbH, Berlin/Boston.)

Published
2020
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18. Utility of systematic TSHR gene testing in adults with hyperthyroidism lacking overt autoimmunity and diffuse uptake on thyroid scintigraphy.

Author

Patel KA, Knight B, Aziz A, Babiker T, Tamar A, Findlay J, Cox S, Dimitropoulos I, Tysoe C, Panicker V, and Vaidya B

Subjects
Adult, Cross-Sectional Studies, Diagnosis, Differential, Genetic Testing, Germ-Line Mutation, Graves Disease diagnosis, Humans, Hyperthyroidism diagnosis, Hyperthyroidism diagnostic imaging, Hyperthyroidism genetics, Radionuclide Imaging methods, United Kingdom, DNA Mutational Analysis, Hyperthyroidism congenital, Receptors, Thyrotropin genetics, Thyroid Gland diagnostic imaging
Abstract

Objective: Patients with hyperthyroidism lacking autoimmune features but showing diffuse uptake on thyroid scintigram can have either Graves' disease or germline activating TSH receptor (TSHR) mutation. It is important to identify patients with activating TSHR mutation due to treatment implication, but the overlapping clinical features with Graves' disease make it difficult to discriminate these two conditions without genetic testing. Our study aimed to assess the potential of systematic TSHR mutation screening in adults with hyperthyroidism, showing diffuse uptake on thyroid scintigraphy but absence of TSH receptor antibodies (TRAb) and clinical signs of autoimmunity., Design: A cross-sectional study of Caucasian adults with hyperthyroidism, managed at three endocrine centres in the South West, UK, from January 2006 to April 2017., Methods: We recruited 78 adult Caucasian patients with hyperthyroidism showing diffuse uptake on 99m Tc-pertechnetate thyroid scintigraphy but without TRAb and other autoimmune clinical features of Graves' disease (such as thyroid-associated ophthalmopathy or dermopathy). Genomic DNA of these patients was analysed for variants in the TSHR gene., Results: Genetic analysis identified 11 patients with four variants in TSHR [p.(Glu34Lys), p.(Asp36His), p.(Pro52Thr) and p.(Ile334Thr)]. None of these variants were pathogenic according to the American College of Medical Genetics and Genomics guideline., Conclusions: Activating TSHR mutations are a rare cause of nonautoimmune adult hyperthyroidism. Our study does not support the routine genetic testing in adult patients with hyperthyroidism showing diffuse uptake on scintigraphy but negative TRAb and lacking extrathyroidal manifestations of Graves' disease., (© 2018 The Authors. Clinical Endocrinology Published by John Wiley & Sons Ltd.)

Published
2019
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19. Promoting Undergraduate Surgical Education: Current Evidence and Students' Views on ESMSC International Wet Lab Course.

Author

Sideris M, Papalois A, Theodoraki K, Dimitropoulos I, Johnson EO, Georgopoulou EM, Staikoglou N, Paparoidamis G, Pantelidis P, Tsagkaraki I, Karamaroudis S, Potoupnis ME, Tsiridis E, Dedeilias P, Papagrigoriadis S, Papalois V, Zografos G, Triantafyllou A, and Tsoulfas G

Subjects
Adult, Female, Germany, Greece, Humans, Male, Surveys and Questionnaires, United Kingdom, Young Adult, Curriculum, Education, Medical, Undergraduate methods, General Surgery education, Simulation Training
Abstract

Background: Undergraduate Surgical Education is becoming an essential element in the training of the future generation of safe and efficient surgeons. Essential Skills in the Management of Surgical Cases (ESMSC), is an international, joint applied surgical science and simulation-based learning wet lab course., Methods: We performed a review of the existing literature on the topic of undergraduate surgical education. Following that, we analyzed the feedback questionnaire received 480 from 2 recent series of ESMSC courses (May 2015, n = 49 and November 2015, n = 40), in order to evaluate European Union students' (UK, Germany, Greece) views on the ESMSC course, as well as on the undergraduate surgical education. Results Using a 10 point graded scale, the overall ESMSC concept was positively evaluated, with a mean score of 9.41 ± 0.72 (range: 8-10) and 8.94 ± 1.1 (range: 7-10). The majority of delegates from both series [9.86 ± 0.43 (range: 8-10) and 9.58 ± 0.91 (range: 6-10), respectively] believed that ESMSC should be incorporated in the undergraduate surgical curriculum. Comparison of responses from the UK to the Greek Medical Student, as well as the findings from the third and fourth year versus the fifth and sixth year Medical Students, revealed no statistically significant differences pertaining to any of the questions (p > 0.05)., Conclusions: Current evidence in the literature supports the enhancement of surgical education through the systematic use of various modalities that provide Simulation-Based Training (SBT) hands-on experience, starting from the early undergraduate level. The findings of the present study are in agreement with these previous reports.

Published
2017
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20. Liquorice-induced apparent mineralocorticoid excess presenting in the emergency department.

Author

Gallacher SD, Tsokolas G, and Dimitropoulos I

Subjects
Aged, Diagnosis, Differential, Female, Glycyrrhizic Acid, Humans, Hypertension etiology, Hypokalemia etiology, Potassium blood, Glycyrrhiza, Mineralocorticoid Excess Syndrome, Apparent blood, Mineralocorticoid Excess Syndrome, Apparent diagnosis, Mineralocorticoid Excess Syndrome, Apparent physiopathology
Abstract

A 65-year-old woman with a background of myalgic encephalitis, who was taking alternative medicines and dietary supplements, presented with hypokalaemia and hypertension. After a thorough history it became apparent that this was most likely secondary to regular consumption of liquorice tea. The patient was advised to discontinue drinking this tea and was discharged. Follow-up showed normalising blood pressure and hypokalaemia, with a normal aldosterone:renin ratio., (© Royal College of Physicians 2017. All rights reserved.)

Published
2017
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21. Evaluating the educational environment of an international animal model-based wet lab course for undergraduate students.

Author

Sideris MC, Papalois AE, Athanasiou T, Dimitropoulos I, Theodoraki K, Dos Santos FS, Paparoidamis G, Staikoglou N, Pissas D, Whitfield PC, Rampotas A, Papagrigoriadis S, Papalois V, Zografos G, and Tsoulfas G

Abstract

Background: Essential Skills in the management of Surgical Cases - ESMSC is an International Combined Applied Surgical Science and Wet Lab course aimed at the undergraduate level. ESMSC combines interactive basic science workshops and case-based learning, with basic surgical training modules (BST) on Ex Vivo and In Vivo swine model. In Vivo Dissections include more advanced modules i.e. Abdominal Anatomy Dissections and Cardiac Transplant., Aim: To evaluate the educational environment of a novel course, as well as to compare Medical students' perceptions across various groups., Materials and Methods: 83 Delegates from King's College London (KCL) and several Hellenic Medical Schools attended the ESMSC course. The DREEM inventory was distributed upon completion of the modules., Results: The mean overall score for DREEM inventory was 148.05/200(99-196, SD = 17.90). Cronbach's Alpha value was 0.818, indicating good internal consistency of the data. Year 3/4 Students have a significantly positive "Perception of Learning", when compared to Year 5/6 (36.43 vs. 33.75, p = 0.017). KCL Students have a more positive view of the course compared to their Greek counterparts (155.19 vs. 145.62/200, p = 0.034). No statistical significant difference was noted when comparing male vs. female students (p > 0.05)., Conclusions: Students seem to positively rate the ESMSC educational environment. Junior as well as KCL students appear to be more enthusiastic. Further research should focus on the optimal strategy for early involvement and motivation of various students' groups in BST.

Published
2016
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