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2. Frailty and Cognitive Function in Middle-Aged and Older Adults With Congenital Heart Disease

Author

Sasikumar, Navaneetha, Enomoto, Junko, Mizuno, Yoshiko, Leong, Ming Chern, Binto Sabran, Izzatun Nafsi, Ladak, Laila Akbar, Hasan, Babar, Siddiqui, Ayat, Moon, Ju Ryoung, Huh, June, Yang, Hsiao-Ling, Wang, Jou-Kou, Lu, Chun-Wei, Demir, Fatma, Öden, Tuğba, Tefera, Endale, Mwita, Julius, Ambassa, Jean-Claude, Mvondo, Charles, Fanka, Marcel, Yadeta, Dejuma, Alemayehu, Mulualem, Leye, Mohamed, Gueye, Khadija, Gabriel, Harald, Svhneider, Matthias, Seeliger, Selina, Budts, Werner, Van De Bruaene, Alexander, Moons, Philip, Goossens, Eva, Van Bulck, Liesbet, Rassart, Jessica, Luyckx, Koen, De Hosson, Michele, De Backer, Julie, Kaneva, Anna, Markova, Mila, Lykkeberg, Birgitte, Biyai, Miriam, Ladouceur, Magalie, Boubrit, Anissa, Thambo, Jean-Benoît, Ruissel, Amandine, Jore, Cecile, Amedro, Pascal, Abassi, Hamouda, Soltani, Sonia, Bredy, Charlene, Giannakoulas, George, Kosmidis, Diamantis, Ntiloudi, Despina, Callus, Edward, Pagliuca, Silvana, Bertoldo, Enrico Giuseppe, Fiolo, Valentina, Caruana, Maryanne, Swain, Justine, Grech, Neil, Xuereb, Rachel, Craus, Sarah, Bonello, Maria, Borg, Darren, Farrugia, Paul, Cardona, Joanne, Estensen, Mette-Elise, Andresen, Brith, Eriksen, Katrine, Areias, Maria Emília, Miranda, Joana, Areias, José Carlos, Cruz, Cristina, Macedo, Filipe, Ribeiro Nunes, Filipa Manuela, Barbosa de Bessa, Ana Maria, Espírito Santo, Sara Mafalda, Brito, Paula, Pereira, Marisa, Teixeira, Sofia, Marques, Brenda, Marques, Ana Raquel, Johansson, Bengt, Sandberg, Camilla, Cronesten, Helena, Dellborg, Mikael, Mandalenakis, Zacharias, Mattson, Eva, Christersson, Christina, Robertsson, Louise, Hlebowicz, Joanna, Ternrud, Linda, Thomet, Corina, Ruperti, Javier, Bouchardy, Judith, Brand, Fanny, Rutz, Tobias, Blanche, Coralie, van Melle, Joost P., Boer, Anna, Constantine, Andrew, Gatzoulis, Michael A., Dimopoulos, Konstantinos, Coats, Louise, McParlin, Debbie, Khairy, Paul, Proietti, Anna, Roy, Veronique, Windram, Jonathan, Jandura, Deborah, Jameson, Susan, Major, Melissa, Mahadevan, Vaikom Subremanian, Nguyen, Thomas, Sarwary, Shabir, Saidi, Arwa, Breault, Leah, Colon, Dalia Lopez, Cedars, Ari, Kutty, Shelby, Ko, Jong, Valente, Anne Marie, Brainard, Sarah, Reichman, Jeffrey, Zaidi, Ali, Amlani, Amrin, Jackson, Jamie, Swenski, Taylor, Neville, Steven, Kovacs, Adrienne, McGrath, Lidija, Taunton, Marshall, Kim, Yuli, Carducci, Jessica, Bashey, Saffy, Alday, Luis, Lousararian, Marina, Maisuls, Héctor, Quinteros, Marisa, Lucero, Mónica, Ortiz, Lucia, Amaral, Fernando, Schmidt, Andre, Manso, Paulo Henrique, Pavão, Rafael Brolio, Reyes, Fernando Baraona, Arancibia, M. Francisca, Araujo, John Jairo, Súarez, Alberto Hernadez, Menahem, Samuel, Wijayarathne, Pasangi Madhuka, Daelman, Bo, Kovacs, Adrienne H., Schmidt, André, and de Hosson, Michèle

Published
2024
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5. Anxiety and Depression in Adults With Congenital Heart Disease

Author

Kovacs, Adrienne H., Luyckx, Koen, Thomet, Corina, Budts, Werner, Enomoto, Junko, Sluman, Maayke A., Lu, Chun-Wei, Jackson, Jamie L., Khairy, Paul, Cook, Stephen C., Chidambarathanu, Shanthi, Alday, Luis, Estensen, Mette-Elise, Dellborg, Mikael, Berghammer, Malin, Johansson, Bengt, Mackie, Andrew S., Menahem, Samuel, Caruana, Maryanne, Veldtman, Gruschen, Soufi, Alexandra, Jameson, Susan M., Callus, Edward, Kutty, Shelby, Oechslin, Erwin, Van Bulck, Liesbet, and Moons, Philip

Published
2024
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13. Transcatheter Intervention for Coarctation of the Aorta: A Nordic Population-Based Registry With Long-Term Follow-Up

Author

Eriksson, Peter, Pihkala, Jaana, Jensen, Annette S., Dohlen, Gaute, Liuba, Petru, Wahlander, Hakan, Sjoberg, Gunnar, Hlebowicz, Joanna, Furenas, Eva, Leirgul, Elisabeth, Settergren, Magnus, Vithessonthi, Kanyalak, Nielsen, Niels-Erik, Christersson, Christina, Sondergaard, Lars, Sinisalo, Juha, Nielsen-Kudsk, Jens Erik, Dellborg, Mikael, and Larsen, Signe H.

Published
2023
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15. Long-Term Outcomes After Atrial Switch Operation for Transposition of the Great Arteries

Author

Broberg, Craig S., van Dissel, Alexandra C., Minnier, Jessica, Aboulhosn, Jamil, Kauling, Robert M., Ginde, Salil, Krieger, Eric V., Rodriguez, Fred, III, Gupta, Tripti, Shah, Sangeeta, John, Anitha S., Cotts, Timothy, Kay, W. Aaron, Kuo, Marissa, Dwight, Cindy, Woods, Patricia, Nicolarsen, Jeremy, Sarubbi, Berardo, Fusco, Flavia, Antonova, Petra, Fernandes, Susan, Grewal, Jasmine, Cramer, Jonathan, Khairy, Paul, Gallego, Pastora, O’Donnell, Clare, Hannah, Jane, Dellborg, Mikael, Rodriguez-Monserrate, Carla P., Muhll, Isabelle Vonder, Pylypchuk, Stephen, Magalski, Anthony, Han, Frank, Lubert, Adam M., Kay, Joseph, Yeung, Elizabeth, Roos-Hesselink, Jolien, Baker, David, Celermajer, David S., Burchill, Luke J., Wilson, William M., Wong, Joshua, Kutty, Shelby, and Opotowsky, Alexander R.

Published
2022
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17. Heart failure in patients with congenital heart disease after a cancer diagnosis.

Author

Karazisi, Christina, Dellborg, Mikael, Mellgren, Karin, Giang, Kok Wai, Skoglund, Kristofer, Eriksson, Peter, and Mandalenakis, Zacharias

Subjects
HEART failure patients, CARDIAC patients, CONGENITAL heart disease, CANCER patients, HEART failure
Abstract

Aims: Individuals with congenital heart disease (CHD) are at an increased risk for cancer. As cancer survival rates improve, the prevalence of late side effects, such as heart failure (HF), is becoming more evident. This study aims to evaluate the risk of developing HF following a cancer diagnosis in patients with CHD, compared with those without CHD and with CHD patients who do not have cancer. Methods: CHD patients (n = 69 799) and randomly selected non‐CHD controls (n = 650 406), born in Sweden between 1952 and 2017, were identified from the Swedish National Health Registers and Total Population Register (excluding those with syndromes and transplant recipients). CHD patients who developed cancer (n = 1309) were propensity score‐matched with non‐CHD patients who developed cancer (n = 9425), resulting in a cohort of 1232 CHD patients with cancer and 2602 non‐CHD controls with cancer (after exclusion of individuals with HF prior to cancer diagnosis). In a separate analysis, CHD patients with cancer were propensity score‐matched with CHD patients without cancer (n = 68 490). A total of 1233 CHD patients with cancer and 2257 CHD patients without cancer were included in the study. Results: Among CHD patients with cancer, 73 (5.9%) developed HF during a mean follow‐up time of 8.5 ± 8.7. Comparatively, in the propensity‐matched control population, 29 (1.1%) non‐CHD cancer patients (mean follow‐up time of 7.3 ± 7.5) and 101 (4.5%) CHD patients without cancer (mean follow‐up time of 9.9 ± 9.2) developed HF. CHD patients exhibited a significantly higher risk of HF post‐cancer diagnosis compared with the non‐CHD control group [hazard ratio (HR) 4.39, 95% confidence interval (CI) 2.83–6.81], after adjusting for age at cancer diagnosis and comorbidities. In the analysis between CHD patients with cancer and those without cancer, the results indicated a significantly higher risk of developing HF in CHD patients with cancer (HR 1.53, 95% CI 1.13–2.07). Conclusions: CHD patients face a more than four‐fold increased risk of developing HF after a cancer diagnosis compared with cancer patients without CHD. Among CHD patients, the risk of HF is only modestly higher for those with cancer than for those without cancer. This suggests that the increased HF risk in CHD patients with cancer, relative to non‐CHD cancer patients, may be more attributable to CHD itself than to cancer treatment‐related side effects. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Prognostic Significance of Hemodynamics in Patients With Transposition of the Great Arteries and Systemic Right Ventricle.

Author

Aldweib, Nael, Deghani, Payam, Broberg, Craig S., van Dissel, Alexandra, Altibi, Ahmad, Wong, Joshua, Baker, David, Gindi, Salil, Khairy, Paul, Opotowsky, Alexander R., Shah, Sangeeta, Magalski, Anthony, Cramer, Jonathan, Kauling, Robert M., Dellborg, Mikael, Krieger, Eric V., Yeung, Elizabeth, Roos-Hesselink, Jolien, Aboulhosn, Jamil, and Nicolarsen, Jeremy

Abstract

BACKGROUND: Patients with transposition of the great arteries (TGA) and systemic right ventricle often confront significant adverse cardiac events. The prognostic significance of invasive hemodynamic parameters in this context remains uncertain. Our hypothesis is that the aortic pulsatility index and hemodynamic profiling utilizing invasive measures provide prognostic insights for patients with TGA and a systemic right ventricle. METHODS: This retrospective multicenter cohort study encompasses adults with TGA and a systemic right ventricle who underwent cardiac catheterization. Data collection, spanning from 1994 to 2020, encompasses clinical and hemodynamic parameters, including measured and calculated values such as pulmonary capillary wedge pressure, aortic pulsatility index, and cardiac index. Pulmonary capillary wedge pressure and cardiac index values were used to establish 4 distinct hemodynamic profiles. A pulmonary capillary wedge pressure of ≥15 mm Hg indicated congestion, termed wet, while a cardiac index <2.2 L/min per m2 signified inadequate perfusion, labeled cold. The primary outcome comprised a composite of all-cause death, heart transplantation, or the requirement for mechanical circulatory support. RESULTS: Of 1721 patients with TGA, 242 individuals with available invasive hemodynamic data were included. The median follow-up duration after cardiac catheterization was 11.4 (interquartile range, 7.5–15.9) years, with a mean age of 38.5±10.8 years at the time of cardiac catheterization. Among hemodynamic parameters, an aortic pulsatility index <1.5 emerged as a robust predictor of the primary outcome, with adjusted hazard ratios of 5.90 (95% CI, 3.01–11.62; P<0.001). Among the identified 4 hemodynamic profiles, the cold/wet profile was associated with the highest risk for the primary outcome, with an adjusted hazard ratio of 3.83 (95% CI, 1.63–9.02; P<0.001). CONCLUSIONS: A low aortic pulsatility index (<1.5) and the cold/wet hemodynamic profile are linked with an elevated risk of adverse long-term cardiac outcomes in patients with TGA and systemic right ventricle. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Corrigendum to “Risk of cancer in young and older patients with congenital heart disease and the excess risk of cancer by syndromes, organ transplantation and cardiac surgery: Swedish health registry study (1930–2017)” [The Lancet Regional Health–Europe 18 (2022) 100407]

Author

Karazisi, Christina, primary, Dellborg, Mikael, additional, Mellgren, Karin, additional, Giang, Kok Wai, additional, Skoglund, Kristofer, additional, Eriksson, Peter, additional, and Mandalenakis, Zacharias, additional

Published
2024
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24. Quality of life in Maltese adults with congenital heart disease: a second look

Author

Caruana, Maryanne, primary, Moons, Philip, additional, Kovacs, Adrienne H., additional, Luyckx, Koen, additional, Thomet, Corina, additional, Budts, Werner, additional, Sluman, Maayke, additional, Eriksen, Katrine, additional, Dellborg, Mikael, additional, Berghammer, Malin, additional, Johansson, Bengt, additional, Soufi, Alexandra, additional, Callus, Edward, additional, Grech, Victor, additional, and Apers, Silke, additional

Published
2024
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25. Time to childbirth and assisted reproductive treatment in women with congenital heart disease

Author

Jonsson, Sara, primary, Sundström-Poromaa, Inger, additional, Johansson, Bengt, additional, Alenius Dahlqvist, Jenny, additional, Christersson, Christina, additional, Dellborg, Mikael, additional, Trzebiatowska-Krzynska, Alexandra, additional, Sörensson, Peder, additional, Thilén, Ulf, additional, Wikström, Anna-Karin, additional, and Bay, Annika, additional

Published
2024
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27. Pain in adults with congenital heart disease - An international perspective

Author

Leibold, Allison, Eichler, Erin, Chung, Sukyung, Moons, Philip, Kovacs, Adrienne H., Luyckx, Koen, Apers, Silke, Thomet, Corina, Budts, Werner, Enomoto, Junko, Sluman, Maayke A., Wang, Jou-Kou, Jackson, Jamie L., Khairy, Paul, Cook, Stephen C., Chidambarathanu, Shanthi, Alday, Luis, Oechslin, Erwin, Eriksen, Katrine, Dellborg, Mikael, Berghammer, Malin, Johansson, Bengt, Mackie, Andrew S., Menahem, Samuel, Caruana, Maryanne, Veldtman, Gruschen, Soufi, Alexandra, White, Kamila, Callus, Edward, Kutty, Shelby, and Fernandes, Susan M.

Published
2021
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31. Atrial arrhythmias and patient-reported outcomes in adults with congenital heart disease: An international study

Author

Casteigt, Benjamin, Samuel, Michelle, Laplante, Laurence, Shohoudi, Azadeh, Apers, Silke, Kovacs, Adrienne H., Luyckx, Koen, Thomet, Corina, Budts, Werner, Enomoto, Junko, Sluman, Maayke A., Lu, Chun-Wei, Jackson, Jamie L., Cook, Stephen C., Chidambarathanu, Shanthi, Alday, Luis, Eriksen, Katrine, Dellborg, Mikael, Berghammer, Malin, Johansson, Bengt, Mackie, Andrew S., Menahem, Samuel, Caruana, Maryanne, Veldtman, Gruschen, Soufi, Alexandra, Fernandes, Susan M., White, Kamila, Callus, Edward, Kutty, Shelby, Brouillette, Judith, Moons, Philip, and Khairy, Paul

Published
2021
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32. Patient-Reported Outcomes in Adults With Congenital Heart Disease Following Hospitalization (from APPROACH-IS)

Author

Moons, Philip, Luyckx, Koen, Thomet, Corina, Budts, Werner, Enomoto, Junko, Sluman, Maayke A., Wang, Jou-Kou, Jackson, Jamie L., Khairy, Paul, Cook, Stephen C., Chidambarathanu, Shanthi, Alday, Luis, Oechslin, Erwin, Eriksen, Katrine, Dellborg, Mikael, Berghammer, Malin, Johansson, Bengt, Mackie, Andrew S., Menahem, Samuel, Caruana, Maryanne, Veldtman, Gruschen, Soufi, Alexandra, Fernandes, Susan M., White, Kamila, Callus, Edward, Kutty, Shelby, Apers, Silke, and Kovacs, Adrienne H.

Published
2021
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33. Physical Functioning, Mental Health, and Quality of Life in Different Congenital Heart Defects: Comparative Analysis in 3538 Patients From 15 Countries

Author

Moons, Philip, Luyckx, Koen, Thomet, Corina, Budts, Werner, Enomoto, Junko, Sluman, Maayke A., Lu, Chun-Wei, Jackson, Jamie L., Khairy, Paul, Cook, Stephen C., Chidambarathanu, Shanthi, Alday, Luis, Eriksen, Katrine, Dellborg, Mikael, Berghammer, Malin, Johansson, Bengt, Mackie, Andrew S., Menahem, Samuel, Caruana, Maryanne, Veldtman, Gruschen, Soufi, Alexandra, Fernandes, Susan M., White, Kamila, Callus, Edward, Kutty, Shelby, Ombelet, Fouke, Apers, Silke, and Kovacs, Adrienne H.

Published
2021
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34. Breastfeeding in primiparous women with congenital heart disease : a register study

Author

Holstad, Ylva, Johansson, Bengt, Lindqvist, Maria, Westergren, Agneta, Sundström Poromaa, Inger, Christersson, Christina, Dellborg, Mikael, Trzebiatowska-Krzynska, Aleksandra, Sörensson, Peder, Thilen, Ulf, Wikström, Anna-Karin, Bay, Annika, Holstad, Ylva, Johansson, Bengt, Lindqvist, Maria, Westergren, Agneta, Sundström Poromaa, Inger, Christersson, Christina, Dellborg, Mikael, Trzebiatowska-Krzynska, Aleksandra, Sörensson, Peder, Thilen, Ulf, Wikström, Anna-Karin, and Bay, Annika

Abstract

Background The number of pregnant women with congenital heart disease (CHD) is rising, and the disease poses increased risks of cardiovascular and obstetric complications during pregnancy, potentially impacting breastfeeding success. This study aimed to investigate breastfeeding in primiparous women with CHD compared to primiparous women without CHD, and to examine potential hindering factors for breastfeeding in women with CHD. Methods The data were gathered between 2014 and 2019 and obtained by merging the Swedish Congenital Heart Disease Register (SWEDCON) with the Swedish Pregnancy Register. Primiparous women ≥ 18 years of age with CHD (n = 578) were matched by age and municipality to 3049 women without CHD, giving birth after 22 gestational weeks. Multivariable logistic regression analysis was used to identify factors associated with non-breastfeeding in women with CHD. Results Fewer women with CHD breastfed than women without CHD two days (94% vs. 97%, p = 0.001) and four weeks after birth (84% vs. 89%, p = 0.006). When all women were analysed, having CHD was associated with non-breastfeeding at both two days and four weeks after birth. For women with CHD, body mass index (BMI) ≥ 30 (OR 3.1; 95% CI 1.4, 7.3), preterm birth (OR 6.4; 95% CI 2.1, 19.0), self-reported history of psychiatric illness (OR 2.4; 95% CI 1.2, 5.1), small for gestational age (OR 4.2; 95% CI 1.4, 12.2), and New York Heart Association Stages of Heart Failure class II − III (OR 6.0; 95% CI 1.4, 26.7) were associated with non-breastfeeding two days after birth. Four weeks after birth, factors associated with non-breastfeeding were BMI ≥ 30 (OR 4.3; 95% CI 2.1, 9.0), self-reported history of psychiatric illness (OR 2.2; 95% CI 1.2, 4.2), and preterm birth (OR 8.9; 95% CI 2.8, 27.9). Conclusions The study shows that most women with CHD breastfeed, however, at a slightly lower proportion compared to women without CHD. In addition, factors related to the heart disease were not associated with non

Published
2024
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35. Time to childbirth and assisted reproductive treatment in women with congenital heart disease

Author

Jonsson, Sara, Sundström Poromaa, Inger, Johansson, Bengt, Alenius Dahlqvist, Jenny, Christersson, Christina, Dellborg, Mikael, Trzebiatowska-Krzynska, Alexandra, Sörensson, Peder, Thilen, Ulf, Wikström, Anna-Karin, Bay, Annika, Jonsson, Sara, Sundström Poromaa, Inger, Johansson, Bengt, Alenius Dahlqvist, Jenny, Christersson, Christina, Dellborg, Mikael, Trzebiatowska-Krzynska, Alexandra, Sörensson, Peder, Thilen, Ulf, Wikström, Anna-Karin, and Bay, Annika

Abstract

Objective To investigate the time to first childbirth and to compare the prevalence of assisted reproductive treatment (ART) in women with congenital heart disease (CHD) compared with women without CHD. Methods All women in the national register for CHD who had a registered first childbirth in the Swedish Pregnancy Register between 2014 and 2019 were identified. These individuals (cases) were matched by birth year and municipality to women without CHD (controls) in a 1:5 ratio. The time from the 18th birthday to the first childbirth and the prevalence of ART was compared between cases and controls. Results 830 first childbirths in cases were identified and compared with 4137 controls. Cases were slightly older at the time for first childbirth (28.9 vs 28.5 years, p=0.04) and ART was more common (6.1% vs 4.0%, p<0.01) compared with controls. There were no differences in ART when stratifying for the complexity of CHD. For all women, higher age was associated with ART treatment (OR 1.24, 95% CI 1.20 to 1.28). Conclusions Women with and without CHD who gave birth to a first child did so at similar ages. ART was more common in women with CHD, but disease severity did not influence the need for ART. Age was an important risk factor for ART also in women with CHD and should be considered in consultations with these patients.

Published
2024
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36. Symptoms during pregnancy in primiparous women with congenital heart disease

Author

Bay, Annika, Berghammer, Malin, Burström, Åsa, Holstad, Ylva, Christersson, Christina, Dellborg, Mikael, Trzebiatowska-Krzynska, Aleksandra, Sörensson, Peder, Thilén, Ulf, Johansson, Bengt, Bay, Annika, Berghammer, Malin, Burström, Åsa, Holstad, Ylva, Christersson, Christina, Dellborg, Mikael, Trzebiatowska-Krzynska, Aleksandra, Sörensson, Peder, Thilén, Ulf, and Johansson, Bengt

Abstract

Background: As more women with congenital heart disease (CHD) are reaching childbearing age, it becomes more common for their symptoms to be evaluated during pregnancy. However, pregnancy-related symptoms are similar to those caused by heart disease. This study investigated the prevalence of factors associated with symptoms during pregnancy in women with CHD. Methods: The national birth register was searched for primiparous women with CHD who were registered in the national quality register for patients with CHD. Results: Symptoms during the third trimester were reported in 104 of 465 evaluated women. The most common symptom was palpitations followed by dyspnea. Factors associated with symptoms were tested in a univariable model; higher NYHA classification (>1) (OR 11.3, 95%CI 5.5–23.2), low physical activity (≤3 h/week) (OR 2.1 95%CI 1.3–3.6) and educational level ≤ 12 years (OR 1.9 95%CI 1.2–3.0) were associated with having symptoms. In multivariable analysis, low physical activity level (OR 2.4 95%CI 1.2–5.0) and higher NYHA class (OR 11.3 95%CI 5.0–25.6) remained associated with symptoms during pregnancy. There were no cases with new onset of impaired systemic ventricular function during pregnancy. Conclusion: Symptoms during pregnancy are common in women with CHD but are often already present before pregnancy. Because ordinary symptoms during pregnancy often overlap with symptoms of heart disease, it is important to know if symptoms were present before pregnancy and if they became worse during pregnancy. These results should be included in pre-pregnancy counselling and considered in the monitoring during pregnancy.

Published
2024
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37. Self-rated health in primiparous women with congenital heart disease before, during and after pregnancy : A register study

Author

Holstad, Ylva, Johansson, Bengt, Lindqvist, Maria, Westergren, Agneta, Sundström Poromaa, Inger, Christersson, Christina, Dellborg, Mikael, Trzebiatowska-Krzynska, Aleksandra, Sörensson, Peder, Thilén, Ulf, Wikström, Anna-Karin, Bay, Annika, Holstad, Ylva, Johansson, Bengt, Lindqvist, Maria, Westergren, Agneta, Sundström Poromaa, Inger, Christersson, Christina, Dellborg, Mikael, Trzebiatowska-Krzynska, Aleksandra, Sörensson, Peder, Thilén, Ulf, Wikström, Anna-Karin, and Bay, Annika

Abstract

Background. Poor maternal self-rated health in healthy women is associated with adverse neonatal outcomes, but knowledge about self-rated health in pregnant women with congenital heart disease (CHD) is sparse. This study, therefore, investigated self-rated health before, during, and after pregnancy in women with CHD and factors associated with poor self-rated health. Methods. The Swedish national registers for CHD and pregnancy were merged and searched for primiparous women with data on self-rated health; 600 primiparous women with CHD and 3062 women in matched controls. Analysis was performed using descriptive statistics, chi-square test and logistic regression. Results. Women with CHD equally often rated their health as poor as the controls before (15.5% vs. 15.8%, p = .88), during (29.8% vs. 26.8% p = .13), and after pregnancy (18.8% vs. 17.6% p = .46). None of the factors related to heart disease were associated with poor self-rated health. Instead, factors associated with poor self-rated health during pregnancy in women with CHD were ≤12 years of education (OR 1.7, 95%CI 1.2–2.4) and self-reported history of psychiatric illness (OR 12.6, 95%CI 1.4–3.4). After pregnancy, solely self-reported history of psychiatric illness (OR 5.2, 95%CI 1.1–3.0) was associated with poor self-rated health. Conclusion. Women with CHD reported poor self-rated health comparable to controls before, during, and after pregnancy, and factors related to heart disease were not associated with poor self-rated health. Knowledge about self-rated health may guide professionals in reproductive counselling for women with CHD. Further research is required on how pregnancy affects self-rated health for the group in a long-term perspective.

Published
2024
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39. Implantable cardioverter-defibrillators and patient-reported outcomes in adults with congenital heart disease: An international study

Author

Lévesque, Valérie, Laplante, Laurence, Shohoudi, Azadeh, Apers, Silke, Kovacs, Adrienne H., Luyckx, Koen, Thomet, Corina, Budts, Werner, Enomoto, Junko, Sluman, Maayke A., Lu, Chun-Wei, Jackson, Jamie L., Cook, Stephen C., Chidambarathanu, Shanthi, Alday, Luis, Eriksen, Katrine, Dellborg, Mikael, Berghammer, Malin, Johansson, Bengt, Mackie, Andrew S., Menahem, Samuel, Caruana, Maryanne, Veldtman, Gruschen, Soufi, Alexandra, Fernandes, Susan M., White, Kamila, Callus, Edward, Kutty, Shelby, Brouillette, Judith, Casteigt, Benjamin, Moons, Philip, and Khairy, Paul

Published
2020
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41. Self-rated health in primiparous women with congenital heart disease before, during and after pregnancy – A register study

Author

Holstad, Ylva, primary, Johansson, Bengt, additional, Lindqvist, Maria, additional, Westergren, Agneta, additional, Sundström Poromaa, Inger, additional, Christersson, Christina, additional, Dellborg, Mikael, additional, Trzebiatowska-Krzynska, Aleksandra, additional, Sörensson, Peder, additional, Thilén, Ulf, additional, Wikström, Anna-Karin, additional, and Bay, Annika, additional

Published
2023
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42. Adult congenital heart disease training in Europe: current status, disparities and potential solutions

Author

McMahon, Colin J, primary, Voges, Inga, additional, Jenkins, Petra, additional, Brida, Margarita, additional, van der Bosch, Annemien E, additional, Dellborg, Mikael, additional, Heying, Ruth, additional, Stein, Jörg I, additional, Georgiev, Borislav, additional, Mesihovic-Dinarevic, Senka, additional, Prokšelj, Katja, additional, Oskarsson, Gylfi, additional, Frogoudaki, Alexandra, additional, Karagöz, Tevfik, additional, Jossif, Antonis, additional, Doros, Gabriela, additional, Nielsen, Dorte, additional, Jalanko, Mikko, additional, Sanchez Perez, Inmaculada, additional, Alvares, Sílvia, additional, Estensen, Mette-Elise, additional, Petropoulos, Andreas, additional, Tagen, Raili, additional, Gumbienė, Lina, additional, Michel-Behnke, Ina, additional, Olejnik, Peter, additional, Clift, Paul F, additional, Sendzikaite, Skaiste, additional, Albert-Brotons, Dimpna C, additional, Rhodes, Mark, additional, Pitkänen, Olli, additional, Bassareo, Pier Paolo, additional, Gatzoulis, Michael A, additional, Walsh, Kevin, additional, Milanesi, Ornella, additional, Ladouceur, Magalie, additional, Chessa, Massimo, additional, and Budts, Werner, additional

Published
2023
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43. Prevalence and Effects of Cigarette Smoking, Cannabis Consumption, and Co-use in Adults From 15 Countries With Congenital Heart Disease

Author

Moons, Philip, Luyckx, Koen, Kovacs, Adrienne H., Holbein, Christina E., Thomet, Corina, Budts, Werner, Enomoto, Junko, Sluman, Maayke A., Yang, Hsiao-Ling, Jackson, Jamie L., Khairy, Paul, Cook, Stephen C., Chidambarathanu, Shanthi, Alday, Luis, Eriksen, Katrine, Dellborg, Mikael, Berghammer, Malin, Johansson, Bengt, Mackie, Andrew S., Menahem, Samuel, Caruana, Maryanne, Veldtman, Gruschen, Soufi, Alexandra, Fernandes, Susan M., White, Kamila, Callus, Edward, Kutty, Shelby, and Apers, Silke

Published
2019
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44. Differential impact of physical activity type on depression in adults with congenital heart disease: A multi-center international study

Author

Ko, Jong Mi, White, Kamila S., Kovacs, Adrienne H., Tecson, Kristen M., Apers, Silke, Luyckx, Koen, Thomet, Corina, Budts, Werner, Enomoto, Junko, Sluman, Maayke A., Wang, Jou-Kou, Jackson, Jamie L., Khairy, Paul, Cook, Stephen C., Chidambarathanu, Shanthi, Alday, Luis, Eriksen, Katrine, Dellborg, Mikael, Berghammer, Malin, Johansson, Bengt, Mackie, Andrew S., Menahem, Samuel, Caruana, Maryanne, Veldtman, Gruschen, Soufi, Alexandra, Fernandes, Susan M., Callus, Edward, Kutty, Shelby, Moons, Philip, and Cedars, Ari M.

Published
2019
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45. Perceived Health Mediates Effects of Physical Activity on Quality of Life in Patients With a Fontan Circulation

Author

Holbein, Christina E., Veldtman, Gruschen R., Moons, Philip, Kovacs, Adrienne H., Luyckx, Koen, Apers, Silke, Chidambarathanu, Shanti, Soufi, Alexandra, Eriksen, Katrine, Jackson, Jamie L., Enomoto, Junko, Fernandes, Susan M., Johansson, Bengt, Alday, Luis, Dellborg, Mikael, Berghammer, Malin, Menahem, Samuel, Caruana, Maryanne, Kutty, Shelby, Mackie, Andrew S., Thomet, Corina, Budts, Werner, White, Kamila, Sluman, Maayke A., Callus, Edward, Cook, Stephen C., Khairy, Paul, and Cedars, Ari

Published
2019
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47. Geographical variation and predictors of physical activity level in adults with congenital heart disease

Author

Larsson, Lena, Johansson, Bengt, Sandberg, Camilla, Apers, Silke, Kovacs, Adrienne H., Luyckx, Koen, Thomet, Corina, Budts, Werner, Enomoto, Junko, Sluman, Maayke A., Wang, Jou-Kou, Jackson, Jamie L., Khairy, Paul, Cook, Stephen C., Alday, Luis, Eriksen, Katrine, Dellborg, Mikael, Berghammer, Malin, Rempel, Gwen, Menahem, Samuel, Caruana, Maryanne, Tomlin, Martha, Soufi, Alexandra, Fernandes, Susan M., White, Kamila, Callus, Edward, Kutty, Shelby, and Moons, Philip

Published
2019
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48. Religion and spirituality as predictors of patient-reported outcomes in adults with congenital heart disease around the globe

Author

Moons, Philip, Luyckx, Koen, Dezutter, Jessie, Kovacs, Adrienne H., Thomet, Corina, Budts, Werner, Enomoto, Junko, Sluman, Maayke A., Yang, Hsiao-Ling, Jackson, Jamie L., Khairy, Paul, Subramanyan, Raghavan, Alday, Luis, Eriksen, Katrine, Dellborg, Mikael, Berghammer, Malin, Johansson, Bengt, Mackie, Andrew S., Menahem, Samuel, Caruana, Maryanne, Veldtman, Gruschen, Soufi, Alexandra, Fernandes, Susan M., White, Kamila, Callus, Edward, Kutty, Shelby, and Apers, Silke

Published
2019
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49. Breastfeeding in primiparous women with congenital heart disease − a register study.

Author

Holstad, Ylva, Johansson, Bengt, Lindqvist, Maria, Westergren, Agneta, Poromaa, Inger Sundström, Christersson, Christina, Dellborg, Mikael, Trzebiatowska-Krzynska, Aleksandra, Sörensson, Peder, Thilén, Ulf, Wikström, Anna-Karin, and Bay, Annika

Subjects
CONGENITAL heart disease, BREASTFEEDING, RESEARCH funding, PUERPERIUM, LOGISTIC regression analysis, MULTIVARIATE analysis, DESCRIPTIVE statistics, ODDS ratio, WOMEN'S health, CONFIDENCE intervals, DATA analysis software
Abstract

Background: The number of pregnant women with congenital heart disease (CHD) is rising, and the disease poses increased risks of cardiovascular and obstetric complications during pregnancy, potentially impacting breastfeeding success. This study aimed to investigate breastfeeding in primiparous women with CHD compared to primiparous women without CHD, and to examine potential hindering factors for breastfeeding in women with CHD. Methods: The data were gathered between 2014 and 2019 and obtained by merging the Swedish Congenital Heart Disease Register (SWEDCON) with the Swedish Pregnancy Register. Primiparous women ≥ 18 years of age with CHD (n = 578) were matched by age and municipality to 3049 women without CHD, giving birth after 22 gestational weeks. Multivariable logistic regression analysis was used to identify factors associated with non-breastfeeding in women with CHD. Results: Fewer women with CHD breastfed than women without CHD two days (94% vs. 97%, p = 0.001) and four weeks after birth (84% vs. 89%, p = 0.006). When all women were analysed, having CHD was associated with non-breastfeeding at both two days and four weeks after birth. For women with CHD, body mass index (BMI) ≥ 30 (OR 3.1; 95% CI 1.4, 7.3), preterm birth (OR 6.4; 95% CI 2.1, 19.0), self-reported history of psychiatric illness (OR 2.4; 95% CI 1.2, 5.1), small for gestational age (OR 4.2; 95% CI 1.4, 12.2), and New York Heart Association Stages of Heart Failure class II − III (OR 6.0; 95% CI 1.4, 26.7) were associated with non-breastfeeding two days after birth. Four weeks after birth, factors associated with non-breastfeeding were BMI ≥ 30 (OR 4.3; 95% CI 2.1, 9.0), self-reported history of psychiatric illness (OR 2.2; 95% CI 1.2, 4.2), and preterm birth (OR 8.9; 95% CI 2.8, 27.9). Conclusions: The study shows that most women with CHD breastfeed, however, at a slightly lower proportion compared to women without CHD. In addition, factors related to the heart disease were not associated with non-breastfeeding four weeks after birth. Since preterm birth, BMI ≥ 30, and psychiatric illness are associated with non-breastfeeding, healthcare professionals should provide greater support to women with CHD having these conditions. [ABSTRACT FROM AUTHOR]

Published
2024
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