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Your search keyword '"Daglioglu, Kenan"' showing total 24 results
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24 results on '"Daglioglu, Kenan"'

7. Does vancomycin powder topically apply to the peripheral nerve cause perineural fibrosis?

Author

Olguner, Semih Kivanc, Celiktas, Mustafa, Erdogan, Kivilcim Eren, Daglioglu, Kenan, Istemen, Ismail, Arslan, Ali, Acik, Vedat, Okten, Ali Ihsan, and Gezercan, Yurdal

Subjects
ANIMAL models in research, VANCOMYCIN, INFLAMMATION, HISTOPATHOLOGY, FIBROSIS
Abstract

Copyright of Pamukkale Medical Journal is the property of Pamukkale Journal of Medicine and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2021
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8. A New Method Involving Percutaneous Application in the Treatment of Deep Venous Insufficiency: An Experimental Study With Internal Compression Therapy in a Porcine Model.

Author

Yasim, Alptekin, Eroglu, Erdinc, Kocarslan, Sezen, Yoldas, Atila, Acipayam, Mehmet, Kocarslan, Aydemir, and Daglioglu, Kenan

Subjects
ANIMAL experimentation, BIOLOGICAL models, COLLAGEN, CONNECTIVE tissues, EXPERIMENTAL design, FEMORAL vein, GENE expression, GENETICS, IMMUNOHISTOCHEMISTRY, MESSENGER RNA, STAINS & staining (Microscopy), SWINE, VENOUS insufficiency, FIBROSIS, COMPRESSION therapy, CONNECTIVE tissue growth factor, DESCRIPTIVE statistics
Abstract

Introduction: To study the efficiency of internal compression therapy (ICT), a new and promising method of treatment for deep venous insufficiency, how that efficiency is achieved, and its potential side-effects, in a porcine model. Material and Methods: The femoral vein diameters of 4 pigs were first measured. ICT was then applied such as to reduce the diameter of these veins by 50%. The femoral vein diameters of 2 pigs were re-measured after 1 month. The femoral vein and its surrounding tissue were excised for immunohistopathological and genetic examination. The same procedures were applied to the remaining 2 pigs 3 months subsequently. Collagen I and IV immunohistochemical staining and Masson's trichrome and Alcian blue histochemical staining were applied during immunohistopathological examination. Collagen I, III, and IV and connective tissue growth factor (CTGF) mRNA expressions were examined for genetic examination. Results: The femoral vein diameters decreased by approximately 50% after ICT application. This decrease persisted after the first and third months. Histopathological examination revealed loose connective tissue around the venous tissue after the operation, particularly in the third month, together with perivascular fibrosis and increased collagen in connective tissue. No difference was observed between regions with and without ICT application in terms of mucinous degeneration, an indicator of tissue injury, during Alcian blue staining. Genetic examination revealed an increase in collagen I and IV and CTGF mRNA expression in perivascular tissue resulting from ICT application. Conclusion: ICT is effective both in terms of creating a durable tissue around the vein and of increasing collagen tissue and stimulating fibrosis, and has no deleterious side-effects on tissue. [ABSTRACT FROM AUTHOR]

Published
2021
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9. The effectiveness of heliox in acute respiratory distress syndrome

Author

Yilmaz, Sema, Daglioglu, Kenan, Yildizdas, Dincer, Bayram, Ibrahim, Gumurdulu, Derya, and Polat, Sait

Subjects
Diagnosis, Care and treatment, Usage, Research, Respiratory distress syndrome -- Diagnosis -- Care and treatment -- Research, Transmission electron microscopes -- Usage
Published
2013

10. Effects of sodium selenite and amiloride on calvarial calcification in closing small cranial defects

Author

Yilmaz, Dervis Mansuri, Haciyakupoglu, Ersin, Haciyakupoglu, Sebahattin, Polat, Sait, Ozgur, Hulya, Sencar, Leman, Daglioglu, Kenan, and Çukurova Üniversitesi

Subjects
pig, amiloride, cranial defect, autogenous fat, sodium selenite
Abstract

WOS: 000286548500031 PubMed ID: 20672896 Object. Fresh autogenous bone graft is the most preferred osteoplastic material, whether the purpose is cosmetic, psychological, or for the protection of the brain. These grafts are not rejected and do not react immunologically. The aim of this study was to evaluate the efficacy of autogenous fat rolled with bone dust derived from the bur hole in closing small cranial defects. Additionally, the authors examined the morphological and biochemical effects of Na selenite and amiloride on calvarial calcification. Methods. The study group consisted of 20 domestic pigs. These animals were randomly divided into 4 groups. A bur hole with a diameter of 10 mm was made at the right parietal region in all animals, and then the periosteum around the bur hole was cauterized following exposure of the dura mater. The dura was coagulated with bipolar cautery. Group 1 (controls): only a bur hole was opened, and it was then closed with a mixture of the bone dust that had been created during the opening of the bur hole and fat tissue that was taken from the animal's neck. Group 2 (amiloride): 1 nmol/g body weight of amiloride was applied subcutaneously within 15 minutes after closure of the bur hole with bone dust and fat, and then amiloride was applied once a day for 4 weeks. Group 3 (Na selenite): 30 nmol/g body weight of Na selenite was applied subcutaneously within 30 minutes after closure of the bur hole with bone dust and fat, and then Na selenite was applied once a day for 4 weeks. Group 4 (amiloride and Na selenite): 1 nmol/g body weight of amiloride was applied subcutaneously at 15 minutes, and 30 nmol/g body weight of Na selenite was applied subcutaneously at 30 minutes after closure of the bur hole with bone dust and fat, and these 2 injections were repeated once a day for 4 weeks. At the end of 4 weeks, the animals were anesthetized to evaluate the closure of the bur hole. Tissue samples were obtained for ultrastructural and biochemical examination. Results. The defect was covered with diffuse connective tissue in the control group. Although multiple capillary vessels were present, the authors did not observe osteogenic differentiation. Histological examination of the second group revealed osteogenic changes. Although new matrix was formed, calcification was not detected. The authors observed fibroblast, collagen fibers, and dense connective tissue filled with capillary in the third group of pigs, which had undergone Na selenite application. Calcification was not detected in this group. Both connective and osteogenic tissue were observed in specimens obtained in the fourth group, which had undergone amiloride and Na selenite application. Conclusions. The authors experimentally evaluated the supplementary osteogenic effects of Na selenite and amiloride by using them separately and together. The findings seem promising as a lead-in to new studies in restoring cranial defects. (DOI: 10.3171/2010.6.JNS091767)

Published
2011

19. Antitumoral Effect of L. inermis in Mice with EAC

Author

Ozaslan, Mehmet, primary, Zumrutdal, Mehmet Emin, additional, Daglioglu, Kenan, additional, Kilic, Ibrahim Halil, additional, Karagoz, Isik Didem, additional, Kalender, M.E., additional, Tuzcu, Muhittin, additional, Colak, Omer, additional, and Cengiz, Beyhan, additional

Published
2009
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21. Rapid diagnosis and genotyping of Leishmania isolates from cutaneous and visceral leishmaniasis by microcapillary cultivation and polymerase chain reaction–restriction fragment length polymorphism of miniexon region

Author

Serin, Mehmet S., primary, Daglioglu, Kenan, additional, Bagirova, Melahat, additional, Allahverdiyev, Adil, additional, Uzun, Soner, additional, Vural, Zeynep, additional, Kayar, Begum, additional, Tezcan, Seda, additional, Yetkin, Mesut, additional, Aslan, Gonul, additional, Emekdas, Gurol, additional, and Koksal, Fatih, additional

Published
2005
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