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Your search keyword '"CHAHAL, PRITPAL"' showing total 9 results
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9 results on '"CHAHAL, PRITPAL"'

1. Health-related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross-sectional study

Author

Carter, Naomi, Li, Jialin, Xu, Miao, Li, Li, Fan, Xuelan, Zhu, Shuyan, Chahal, Pritpal, and Chattopadhyay, Kaushik

Subjects
Diabetes Mellitus, Type 2, Quality of Life, China
Abstract

Introduction: The burden of type 2 diabetes (T2DM) in China is increasing, with potential impacts on the health-related quality of life (HRQoL) of those who develop the disease. Context-specific assessment of HRQoL and its associated factors informs the development of contextually appropriate interventions to improve HRQoL. This study aimed to determine the HRQoL and its associated factors in people with T2DM at a tertiary care clinic in Ningbo, China. Methods: A cross-sectional survey was undertaken among 406 people with T2DM in 2020–21. The primary outcome was HRQoL measured using EQ VAS and EQ-5D index from the EQ-5D-3L questionnaire. Multivariable regression analysis was used to determine the factors associated with HRQoL scores. Results: The mean (± standard deviation) EQ VAS score was 68.7 (13.8). Median (interquartile range) EQ-5D index was 1 (0.027). Prevalence of problems in HRQoL domains was as follows: pain/discomfort (15.7%), anxiety/depression (13.3%), mobility (5.4%), self-care (3.5%) and managing usual activities (5.2%). The ≥60 years age group had a mean EQ VAS score 8.7 points higher (95% CI 3.4, 13.9; p 10 years had a mean EQ VAS score 8.6 points lower than those with a duration 10 years was associated with a reduction in the EQ-5D index of 0.029 (−0.041, −0.016; p

Published
2022

3. What are the development priorities for management of type 2 diabetes by general practitioners in Ningbo, China: a qualitative study of patients’ and practitioners’ perspectives

Author

Woolley, Angharad, primary, Li, Li, additional, Solomon, Josie, additional, Li, Jialin, additional, Huang, Kai, additional, Chahal, Punam, additional, Chahal, Priya, additional, Tu, Gloria, additional, Chahal, Pritpal, additional, and Chattopadhyay, Kaushik, additional

Published
2020
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7. Measurement of Blood-Retinal Barrier Function in Central Retinal Vein Occlusion

Author

Chahal, Pritpal S., Fallon, Timothy J., and Kohner, Eva M.

Abstract

• Vitreous fluorophotometry was used to measure blood-retinal barrier permeability to fluorescein in eight patients (mean age, 42.9 years; range, 30 to 55 years) with central retinal vein occlusion (CRVO). Permeability coefficient was derived by fitting a mathematical model to the posterior vitreous fluorescence scan and plasma-free fluorescein concentration curve at 60 minutes after intravenous fluorescein sodium (14 mg · kg-1). A permeability index (PI) was estimated by dividing the area under the vitreous fluorescence scan by the area under the plasma-free fluorescein curve. The permeability coefficient and PI were comparable and highly correlated. Initial mean permeability coefficient was 28.78 × 10-7 cm · S-1 (range, 14.42 × 10-7 to 41.10 × 10-7) and 1.89 × 10-7 cm · s-2 (range, 0.96 × 10-7 to 2.76 × 10-7) in eight affected and seven unaffected eyes, respectively. The permeability coefficient and PI in unaffected eyes did not differ significantly from 18 eyes of ten normal subjects. After three to 12 months, permeability coefficient and PI in affected eyes approached the values in the contralateral eyes of four patients with mild and one patient with moderate CRVO but remained elevated in the remaining patients. The permeability coefficient and PI correlated well with changes in severity of retinal appearances on color photographs and fluorescein angiograms. Vitreous fluorophotometry quantitated changes in blood-retinal barrier permeability in CRVO.

Published
1986
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9. Health-related quality of life of people with type 2 diabetes and its associated factors at a tertiary care clinic in Ningbo, China: A cross-sectional study.

Author

Carter N, Li J, Xu M, Li L, Fan X, Zhu S, Chahal P, and Chattopadhyay K

Subjects
Adolescent, Adult, China epidemiology, Cross-Sectional Studies, Health Status, Humans, Pain, Tertiary Healthcare, Young Adult, Diabetes Mellitus, Type 2 complications, Diabetes Mellitus, Type 2 therapy, Quality of Life psychology
Abstract

Introduction: The burden of type 2 diabetes (T2DM) in China is increasing, with potential impacts on the health-related quality of life (HRQoL) of those who develop the disease. Context-specific assessment of HRQoL and its associated factors informs the development of contextually appropriate interventions to improve HRQoL. This study aimed to determine the HRQoL and its associated factors in people with T2DM at a tertiary care clinic in Ningbo, China., Methods: A cross-sectional survey was undertaken among 406 people with T2DM in 2020-21. The primary outcome was HRQoL measured using EQ VAS and EQ-5D index from the EQ-5D-3L questionnaire. Multivariable regression analysis was used to determine the factors associated with HRQoL scores., Results: The mean (± standard deviation) EQ VAS score was 68.7 (13.8). Median (interquartile range) EQ-5D index was 1 (0.027). Prevalence of problems in HRQoL domains was as follows: pain/discomfort (15.7%), anxiety/depression (13.3%), mobility (5.4%), self-care (3.5%) and managing usual activities (5.2%). The ≥60 years age group had a mean EQ VAS score 8.7 points higher (95% CI 3.4, 13.9; p < .001) than the 18-39 years age group. Those with T2DM >10 years had a mean EQ VAS score 8.6 points lower than those with a duration <1 year (-12.8, -4.4; p = .001). A T2DM duration >10 years was associated with a reduction in the EQ-5D index of 0.029 (-0.041, -0.016; p < .001) compared with a duration <1 year., Conclusions: Depression/anxiety and pain/discomfort are important domains of reduced HRQoL for this population. A longer duration of T2DM is associated with reduced HRQoL scores, including both EQ VAS and EQ-5D index. Increasing age may be counterintuitively associated with an increase in EQ VAS score in this population, potentially reflecting a 'paradox of aging' process. Future work should focus on developing, evaluating and implementing interventions to improve HRQoL in T2DM, such as strategies to manage pain and mental health conditions., (© 2022 The Authors. Endocrinology, Diabetes & Metabolism published by John Wiley & Sons Ltd.)

Published
2022
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