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476 results on '"Boucekine, Mohamed"'

3. Prevalence and factors associated with high-risk gastric contents in women admitted to the maternity unit for childbirth: a prospective multicentre cohort study

Author

Bouvet, Lionel, Fabre, Juliette, Roussin, Charlotte, Nadal, Camille, Dezavelle, Sylvain, Vial, Florence, Le Gouez, Agnès, Soued, Mickael, Keita, Hawa, Zein, Waed, Desgranges, François-Pierrick, Thuet, Vincent, Boucekine, Mohamed, Duclos, Gary, Leone, Marc, and Zieleskiewicz, Laurent

Published
2024
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7. Health mediation does not reduce the readmission rate of frequent users of emergency departments living in precarious conditions: what lessons can be learned from this randomised controlled trial?

Author

Rotily, Michel, primary, Persico, Nicolas, additional, Lamouroux, Aurore, additional, Rojas-Vergara, Ana Cristina, additional, Loundou, Anderson, additional, Boucekine, Mohamed, additional, Apostolidis, Themistoklis, additional, Odena, Sophie, additional, Chischportich, Celia, additional, and Auquier, Pascal, additional

Published
2024
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12. Ultra-lung-protective ventilation and biotrauma in severe ARDS patients on veno-venous extracorporeal membrane oxygenation: a randomized controlled study

Author

Guervilly, Christophe, Fournier, Théotime, Chommeloux, Juliette, Arnaud, Laurent, Pinglis, Camille, Baumstarck, Karine, Boucekine, Mohamed, Valera, Sabine, Sanz, Celine, Adda, Mélanie, Bobot, Mickaël, Daviet, Florence, Gragueb-Chatti, Ines, Forel, Jean-Marie, Roch, Antoine, Hraiech, Sami, Dignat-George, Françoise, Schmidt, Matthieu, Lacroix, Romaric, and Papazian, Laurent

Published
2022
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13. Surgical site infection in severe trauma patients in intensive care: epidemiology and risk factors.

Author

Savio, Lucie, Simeone, Pierre, Baron, Sophie, Antonini, François, Bruder, Nicolas, Boussen, Salah, Zieleskiewicz, Laurent, Blondel, Benjamin, Prost, Solène, Baucher, Guillaume, Lebaron, Marie, Florant, Thibault, Boucekine, Mohamed, Leone, Marc, and Velly, Lionel

Subjects
ANTIBIOTICS, RISK assessment, PEARSON correlation (Statistics), PATIENTS, PREDICTION models, T-test (Statistics), RECEIVER operating characteristic curves, FISHER exact test, MULTIPLE regression analysis, EMERGENCY medical services, DESCRIPTIVE statistics, MULTIVARIATE analysis, EVALUATION of medical care, RETROSPECTIVE studies, SYMPTOMS, LONGITUDINAL method, BONE fractures, INTENSIVE care units, RESEARCH, HYPERLACTATEMIA, CREATINE, STATISTICS, SURGICAL site infections, LENGTH of stay in hospitals, MEDICAL screening, SURVIVAL analysis (Biometry), DATA analysis software, COMPARATIVE studies, MIXED infections, GRAM-positive bacteria, BIOMARKERS, DISEASE risk factors
Abstract

Background: Severe trauma is the leading cause of disability and mortality in the patients under 35 years of age. Surgical site infections (SSI) represent a significant complication in this patient population. However, they are often inadequately investigated, potentially impacting the quality of patient outcomes. The aim of this study was to investigate the epidemiology of SSI and risk factors in severe trauma patients. Methods: We conducted a multicenter retrospective cohort study screening the severe trauma patients (STP) admitted to two intensive care units of an academic institution in Marseille between years2018 and 2019. Those who underwent orthopedic or spinal surgery within 5 days after admission were included and classified into two groups according to the occurrence of SSI (defined by the Centers for Disease Control (CDC) international diagnostic criteria) or not. Our secondary goal was to evaluate STP survival at 48 months, risk factors for SSI and microbiological features of SSI. Results: Forty-seven (23%) out of 207 STP developed an SSI. Mortality at 48-months did not differ between SSI and non-SSI patients (12.7% vs. 10.0%; p = 0.59). The fractures of 22 (47%) severe trauma patients with SSI were classified as Cauchoix 3 grade and 18 (38%) SSI were associated with the need for external fixators. Thirty (64%) severe trauma patients with SSI had polymicrobial infection, including 34 (72%) due to Gram-positive cocci. Empirical antibiotic therapy was effective in 31 (66%) cases. Multivariate analysis revealed that risk factors such as low hemoglobin, arterial oxygenation levels, hyperlactatemia, high serum creatinine and glycemia, and Cauchoix 3 grade on the day of surgery were associated with SSI in severe trauma patients. The generated predictive model showed a good prognosis performance with an AUC of 0.80 [0.73–0.88] and a high NPV of 95.9 [88.6–98.5] %. Conclusions: Our study found a high rate of SSI in severe trauma patients, although SSI was not associated with 48-month mortality. Several modifiable risk factors for SSI may be effectively managed through enhanced perioperative monitoring and the implementation of a patient blood management strategy. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Compliance with Early Long-Term Prophylaxis Guidelines for Severe Hemophilia A

Author

Aouba, Achille, Harroche, Annie, Legrand, Faezeh, Rothschild, Chantal, Torchet, Marie-Françoise, d’Oiron, Roseline, Lambert, Thierry, Laurian, Yves, Rafowicz, Anne, Biernat, Jennifer, Goudemand, Jenny, Parquet, Armelle, Tintillier, Véronique, Wibaut, Bénédicte, Assollant, Anne Durin, Meunier, Sandrine, Négrier, Claude, Castet, Sabine, Guérin, Viviane, Huguenin, Yohann, Micheau, Marguerite, Ryman, Anne, Chambost, Hérve, Falaise, Céline, Claeyssens, Ségolène, Thiercelin-Legrand, Marie Françoise, Fiks-Sigaud, Marianne, Fouassier, Marc, Fressinaud, Edith, Trossaert, Marc, Voisin, Sophie, Faradji, Albert, Lutz, Patrick, Briquel, Marie Elisabeth, Frotscher, Birgit, Fimbel, Béatrice, Gruel, Yves, Guerois, Claude, Regina, Sandra, Valentin, Jean Baptiste, Biron Andreani, Christine, Codine, Philippe, Donadio, Daniel, Navarro, Robert, Rospide, Paola, Schved, Jean-François, Berger, Claire, Collet, Bénédicte, Derlon, Annie Borel, Gautier, Philippe, Bayart, Sophie, Guillet, Ben⊚ıt, Borg, JeanneYvonne, Dumesnil, Cécile, Normand, Charline, Schneider, Pascale, Tron, Philippe, Vannier, Jean-Pierre, Dutrillaux, Fabienne, Volot, Fabienne, Gembara, Piotr, Marques-Verdier, Alain, Adjaoud, Dalila, Barro, Claire, Pernod, Gilles, Polack, Ben⊚ıt, Pouzol, Patricia, Ounnoughene, Nadra, Paugy, Patricia, Robert, Valérie, Stieltjes, Natalie, Bastenaire, Brigitte, de Raucourt, Emmanuelle, Peynet, Jocelyne, Li-Thiao-Te, Valérie, Pautard, Brigitte, Behar, Catherine, Gorde, Stéphanie, Munzer, Martine, Gay, Valérie, Benz Lemoine, Elisabeth, Macchi, Laurent, De Lumley, Lionel, Gaillard, Solange, Oudot, Caroline, Deville, Anne, Monpoux, Fabrice, Bertrand, Marie Anne, Pan-Petesch, Brigitte, Hassoun, Abel, Coatmelec, Brigitte, Beurrier, Philippe, Damay, Michèle, Moreau, Philippe, Pouille-Lievin, Odile, Schoepfer, Caroline, Tarral, Eliane, Bianchin, Monique, Nguyen, Joël, Pincemaille, Olivier, Peter, Marie-Odile, Saultier, Paul, Guillaume, Yves, Demiguel, Virginie, Borel-Derlon, Annie, Vinciguerra, Christine, Boucekine, Mohamed, Baumstarck, Karine, Calvez, Thierry, and Chambost, Hervé

Published
2021
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19. Impact of Graft Function on Health Status and Quality of Life in Very Long-Term Survivors Who Received an HSCT for Inborn Errors of Immunity, a Prospective Study of the CEREDIH

Author

Petit, Audrey, Neven, Bénédicte, Min, Victoria, Mahlaoui, Nizar, Moshous, Despina, Castelle, Martin, Allouche, Maya, Stérin, Arthur, Visentin, Sandrine, Saultier, Paul, Boucekine, Mohamed, Shawket, Alaa Mustafa, Picard, Capucine, Auquier, Pascal, Michel, Gérard, Fischer, Alain, and Barlogis, Vincent

Published
2023
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21. Quality of life of siblings of adolescents with severe haemophilia (FRATHEMO): An ancillary study to the TRANSHEMO project.

Author

Nguyen, Ngoc Anh Thu, Auquier, Pascal, Beltran Anzola, Any, Harroche, Annie, Huguenin, Yoann, Hochart, Audrey, Meunier, Sandrine, Frotscher, Birgit, Nguyen, Philippe, Schneider, Pascale, Berger, Claire, Lebreton, Aurélien, Vanderbecken, Stéphane, De Raucourt, Emmanuelle, D'Oiron, Roseline, Oudot‐Challard, Caroline, Baumstarck, Karine, Boucekine, Mohamed, Tabélé, Clémence, and Rosso‐Delsemme, Natacha

Subjects
QUALITY of life, HEMOPHILIA, SIBLINGS, TRANSITION to adulthood, TEENAGERS
Abstract

This article discusses a study conducted to assess the quality of life (QoL) of siblings of adolescents with severe haemophilia. The study found that the QoL of these siblings was not significantly different from that of the affected adolescents, and it was actually higher than that of the age- and sex-matched French general population. The study also identified several determinants of QoL, including age, gender, anxiety symptoms, coping strategies, prosocial behavior, and emotional intelligence. The findings suggest that siblings of individuals with haemophilia generally have good QoL, but there is a need to address potential psychological distress and behavioral problems. The study was conducted with the participation of various medical professionals, researchers, and representatives from the French Association for People with Hemophilia. The data used in the study was provided by the FranceCoag registry. The study was funded by grants from Bayer Consumer Care AG and the University Hospital of Marseille. The authors declare no conflicts of interest. The data from the study is not publicly available due to privacy and ethical restrictions. The study was approved by the Ethical Research Committees and conducted in accordance with applicable privacy requirements and ethical principles. [Extracted from the article]

Published
2024
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22. Gastric peroral endoscopic myotomy versus botulinum toxin injection for the treatment of refractory gastroparesis: results of a double-blind randomized controlled study.

Author

Gonzalez, Jean-Michel, Mion, François, Pioche, Mathieu, Garbay, Victor, Baumstarck, Karine, Boucekine, Mohamed, Debourdeau, Antoine, Rivory, Jérôme, Barthet, Marc, and Vitton, Véronique

Subjects
BOTULINUM toxin, BOTULINUM A toxins, GASTROPARESIS, MYOTOMY, GASTRIC emptying, PYLORUS
Abstract

Introduction Gastric peroral endoscopic myotomy (G-POEM) is a promising technique for treating refractory gastroparesis. We present the first double-blind randomized study comparing the clinical efficacy of G-POEM versus pyloric botulinum toxin injection (BTI). Methods This randomized study, conducted in two expert centers, enrolled patients with refractory gastroparesis, medically managed for >6 months and confirmed by gastric emptying scintigraphy (GES), into two groups, G-POEM versus BTI, with follow-up of 1 year. The primary end point was the 3-month clinical efficacy, defined as a >1-point decrease in the mean Gastroparesis Cardinal Symptom Index (GCSI) score. Secondary end points were: 1-year efficacy, GES evolution, adverse events, and quality of life. Results 40 patients (22 women; mean age 48.1 [SD 17.4]), with mean symptom duration of 5.8 (SD 5.7) years, were randomized. Etiologies included idiopathic (n=18), diabetes (n=11), postoperative (n=6), and mixed (n=4). G-POEM showed a higher 3-month clinical success than BTI (65% vs. 40%, respectively; P =0.10), along with non-significantly higher 1-year clinical success (60% vs. 40%, respectively) on intention-to-treat analysis. The GCSI decreased in both groups at 3 months and 1 year. Only three minor adverse events occurred in the G-POEM group. The GES improvement rate was 72% in the G-POEM group versus 50% in the BTI group (non-significant). Conclusion G-POEM seems to have a higher clinically relevant success rate than BTI, but this was not statistically demonstrated. This study confirms the interest in treatments targeting the pylorus, either mechanically or chemically, for managing refractory gastroparesis. [ABSTRACT FROM AUTHOR]

Published
2024
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27. Comparative study of lung ultrasound and chest computed tomography scan in the assessment of severity of confirmed COVID-19 pneumonia

Author

Zieleskiewicz, Laurent, Markarian, Thibaut, Lopez, Alexandre, Taguet, Chloé, Mohammedi, Neyla, Boucekine, Mohamed, and Baumstarck, Karine

Subjects
Bacterial pneumonia -- Health aspects -- Comparative analysis -- Usage, Pneumonia -- Health aspects -- Comparative analysis -- Usage, Oximetry -- Usage -- Comparative analysis -- Health aspects, CT imaging -- Usage -- Health aspects -- Comparative analysis, Severe acute respiratory syndrome -- Usage -- Health aspects -- Comparative analysis, Coronaviruses -- Health aspects -- Usage -- Comparative analysis, Diagnostic imaging -- Health aspects -- Comparative analysis -- Usage, Health care industry
Abstract

Purpose The relationship between lung ultrasound (LUS) and chest computed tomography (CT) scans in patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia is not clearly defined. The primary objective of our study was to assess the performance of LUS in determining severity of SARS-CoV-2 pneumonia compared with chest CT scan. Secondary objectives were to test the association between LUS score and location of the patient, use of mechanical ventilation, and the pulse oximetry (SpO.sub.2)/fractional inspired oxygen (FiO.sub.2) ratio. Methods A multicentre observational study was performed between 15 March and 20 April 2020. Patients in the Emergency Department (ED) or Intensive Care Unit (ICU) with acute dyspnoea who were PCR positive for SARS-CoV-2, and who had LUS and chest CT performed within a 24-h period, were included. Results One hundred patients were included. LUS score was significantly associated with pneumonia severity assessed by chest CT and clinical features. The AUC of the ROC curve of the relationship of LUS versus chest CT for the assessment of severe SARS-CoV-2 pneumonia was 0.78 (CI 95% 0.68-0.87; p < 0.0001). A high LUS score was associated with the use of mechanical ventilation, and with a SpO.sub.2/FiO.sub.2 ratio below 357. Conclusion In known SARS-CoV-2 pneumonia patients, the LUS score was predictive of pneumonia severity as assessed by a chest CT scan and clinical features. Within the limitations inherent to our study design, LUS can be used to assess SARS-CoV-2 pneumonia severity., Author(s): Laurent Zieleskiewicz [sup.1] [sup.2], Thibaut Markarian [sup.3], Alexandre Lopez [sup.1], Chloé Taguet [sup.3], Neyla Mohammedi [sup.1], Mohamed Boucekine [sup.4], Karine Baumstarck [sup.4], Guillaume Besch [sup.5], Gautier Mathon [sup.6], Gary [...]

Published
2020
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35. P1672: OCCUPATIONAL INTEGRATION OF ADULTS WITH SEVERE HAEMOPHILIA (INTHEMO): A STUDY BASED ON THE FRANCECOAG REGISTRY

Author

Nguyen, Ngoc Anh Thu, primary, Auquier, Pascal, additional, Anzola, Any Beltran, additional, D’oiron, Roseline, additional, Lambert, Thierry, additional, Falaise, Céline, additional, Biron, Christine, additional, Lienhart, Anne, additional, Goudemand, Jenny, additional, Rauch, Antoine, additional, Wibaut, Bénédicte, additional, Castet, Sabine Marie, additional, Desprez, Dominique, additional, Harroche, Annie, additional, Stieltjes, Natalie, additional, Borel-Derlon, Annie, additional, Trossaërt, Marc, additional, Celli, Amandine, additional, Guillet, Benoît, additional, Bayart, Sophie, additional, Bertrand, Marie-Anne, additional, Fournel, Alexandra, additional, Mourey, Guillaume, additional, Gay, Valérie, additional, Chamouni, Pierre, additional, Raucourt, Emmanuelle DE, additional, Frotscher, Birgit, additional, Martin, Michèle, additional, Puyade, Mathieu, additional, Tardy, Brigitte, additional, Vanderbecken, Stéphane, additional, Genre-Volot, Fabienne, additional, Nguyen, Philippe, additional, Polack, Benoît, additional, Oudot-Challard, Caroline, additional, Girault, Stéphane, additional, Voyer, Annelise, additional, Lebreton, Aurélien, additional, Hassoun, Abel, additional, Moreau, Philippe, additional, Rohrlich, Pierre-Simon, additional, Baumstarck, Karine, additional, Boucekine, Mohamed, additional, Milien, Vanessa, additional, Rosso, Natacha, additional, Tabele, Clemence, additional, Viprey, Marie, additional, Giraud, Nicolas, additional, Sannie, Thomas, additional, Chambost, Hervé, additional, and Resseguier, Noémie, additional

Published
2023
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38. Hippocampal Sparing During Craniospinal Irradiation: What Did We Learn About the Incidence of Perihippocampus Metastases?

Author

Padovani, Laetitia, Chapon, Frédérique, André, Nicolas, Boucekine, Mohamed, Geoffray, Anne, Bourdeau, Franck, Masliah-Planchon, Julien, Claude, Line, Huchet, Aymeri, Laprie, Anne, Supiot, Stephane, Coche-Dequéant, Bernard, Kerr, Christine, Alapetite, Claire, Leseur, Julie, Nguyen, Tandat, Chapet, Sophie, Bernier, Valerie, Bondiau, Pierre-Yves, Noel, Georges, Habrand, Jean Louis, Bolle, Stephanie, Doz, François, Dufour, Christelle, Muracciole, Xavier, and Carrie, Christian

Published
2018
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39. Tailored multicomponent program for discomfort reduction in critically ill patients may decrease post-traumatic stress disorder in general ICU survivors at 1 year

Author

Kalfon, Pierre, Alessandrini, Marine, Boucekine, Mohamed, Renoult, Stéphanie, Geantot, Marie-Agnès, Deparis-Dusautois, Stéphanie, and Berric, Audrey

Subjects
Medical research -- Comparative analysis, Medicine, Experimental -- Comparative analysis, Post-traumatic stress disorder -- Comparative analysis, Health care industry
Abstract

Purpose Reducing discomfort in the intensive care unit (ICU) should have a positive effect on long-term outcomes. This study assessed whether a tailored multicomponent program for discomfort reduction was effective in reducing post-traumatic stress disorder (PTSD) symptoms at 1 year in general ICU survivors. Methods This study is a prospective observational comparative effectiveness cohort study involving 30 ICUs. It was an extension of the IPREA3 study, a cluster-randomized controlled trial designed to assess the efficacy of a tailored multicomponent program to reduce discomfort in critically ill patients. The program included assessment of ICU-related self-perceived discomforts, immediate and monthly feedback to the healthcare team, and site-specific tailored interventions. The exposure was the implementation of this program. The eligible patients were exposed versus unexposed general adult ICU survivors. The prevalence of substantial PTSD symptoms at 1 year was assessed based on the Impact of Event Scale-Revised (IES-R). Results Of the 1537 ICU survivors included in the study, 475 unexposed patients and 344 exposed patients had follow-up data at 1 year: 57 (12.0%) and 21 (6.1%) presented with PTSD at 1 year, respectively (p = 0.004). Considering the clustering and after adjusting for age, gender, McCabe classification, and ICU-related self-perceived overall discomfort score, exposed patients were significantly less likely than unexposed patients to have substantial PTSD symptoms at 1 year (p = 0.015). Conclusions Implementation of a tailored multicomponent program in the ICU that has proved to be effective for reducing self-perceived discomfort in general adult ICU survivors also reduced the prevalence of substantial PTSD symptoms at 1 year. Trial registration ClinicalTrials.gov identifier NCT02762409., Author(s): Pierre Kalfon [sup.1] [sup.2], Marine Alessandrini [sup.2], Mohamed Boucekine [sup.2], Stéphanie Renoult [sup.3], Marie-Agnès Geantot [sup.4], Stéphanie Deparis-Dusautois [sup.5], Audrey Berric [sup.6], Olivier Collange [sup.7], Bernard Floccard [sup.8], Olivier [...]

Published
2019
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43. Validation study of the Medication Adherence Rating Scale. Results from the FACE-SZ national dataset

Author

Fond, Guillaume, Boyer, Laurent, Boucekine, Mohamed, Aden, Latif A., Schürhoff, Franck, Tessier, Arnaud, Andrianarisoa, Meja, Berna, Fabrice, Brunel, Lore, Capdevielle, Delphine, Chereau, Isabelle, Mallet, Jasmina, Denizot, Hélène, Dorey, Jean Michel, Dubertret, Caroline, Dubreucq, Julien, Faget, Catherine, Gabayet, Franck, Rey, Romain, Richieri, Raphaelle, Passerieux, Christine, Schandrin, Aurélie, Urbach, Mathieu, Vidailhet, Pierre, Llorca, Pierre Michel, and Misdrahi, David

Published
2017
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