Search

Your search keyword '"Bottillo, Grazia"' showing total 13 results
Start Over Author "Bottillo, Grazia" Publication Year Range Last 50 years
13 results on '"Bottillo, Grazia"'

2. Contributors

Author

Alfonso, Amparo, primary, Álvarez-Rivera, Gerardo, additional, Barceló, Damia, additional, Berardinelli, Diletta, additional, Berretta, Paolo, additional, Bobály, Balázs, additional, Botana, Ana M., additional, Botana, Luis M., additional, Bottillo, Grazia, additional, Briganti, Stefania, additional, Brunelli, C., additional, Calderón, Carlos, additional, Camera, Emanuela, additional, Čelić, Mira, additional, Chankvetadze, Bezhan, additional, Cifuentes, Alejandro, additional, D’Amato, Maura, additional, Dal Bosco, Chiara, additional, de Alda, Miren Lopez, additional, Di Trana, Annagiulia, additional, Domínguez-Hernández, Cristopher, additional, Donato, Paola, additional, Dugo, Paola, additional, Eylem, Cemil Can, additional, Fan, Yuchen, additional, Farré, Marinella, additional, Garrido Frenich, Antonia, additional, Gentili, Alessandra, additional, Gieroba, Barbara, additional, Gika, Helen, additional, González-Jartín, Jesús M., additional, González-Sálamo, Javier, additional, Goyon, Alexandre, additional, Hamase, Kenji, additional, Hanna-Brown, M., additional, Hartonen, Kari, additional, Hernández-Borges, Javier, additional, Herrero, Miguel, additional, Hradski, J., additional, Iadarola, Paolo, additional, Ibáñez, Elena, additional, Ishii, Chiharu, additional, Jiménez-Skrzypek, Gabriel, additional, Jóźwiak, Krzysztof, additional, Kataoka, Hiroyuki, additional, Koçak, Engin, additional, Koga, Reiko, additional, Kozak, Radoslaw P., additional, Lämmerhofer, Michael, additional, Lestremau, F., additional, Li, Shaoping, additional, López-Ruiz, Rosalía, additional, Maiellaro, Miriam, additional, Mandrioli, Roberto, additional, Marazuela, M.D., additional, Marín-Sáez, Jesús, additional, Matys, Joanna, additional, Mercolini, Laura, additional, Michalke, Bernhard, additional, Mondello, Luigi, additional, Montanari, Eva, additional, Nemutlu, Emirhan, additional, Nischwitz, Volker, additional, Ottaviani, Monica, additional, Parshintsev, Jevgeni, additional, Peluso, Paola, additional, Perez, Sandra, additional, Petrovic, Mira, additional, Plumb, Robert S, additional, Poole, Colin F., additional, Protti, Michele, additional, Qin, You, additional, Riekkola, Marja-Liisa, additional, Romero-González, Roberto, additional, Royle, Louise, additional, Sánchez-Martínez, José David, additional, Sciuto, Lorenzo, additional, Socas-Rodríguez, Bárbara, additional, Szucs, R., additional, Theodoridis, Georgios, additional, Tini, Anastasio, additional, Todoroki, Kenichiro, additional, Valdés, Alberto, additional, Vieytes, Mercedes R., additional, Viglio, Simona, additional, Wilson, Ian D, additional, Zhang, Kelly, additional, and Zhao, Jing, additional

Published
2023
Full Text
View/download PDF

5. Exploring sexual function in adrenal insufficiency: findings from the Dual RElease hydrocortisone versus conventionAl glucocorticoid replaceMent therapy in hypocortisolism (DREAM) trial

Author

Hasenmajer, Valeria, primary, De Alcubierre, Dario, additional, Ferrari, Davide, additional, Minnetti, Marianna, additional, Bonaventura, Ilaria, additional, Pofi, Riccardo, additional, Simeoli, Chiara, additional, Tomaselli, Alessandra, additional, Sciarra, Francesca, additional, Bottillo, Grazia, additional, Angelini, Francesco, additional, Cozzolino, Alessia, additional, Venneri, Mary Anna, additional, Jannini, Emmanuele A., additional, Gianfrilli, Daniele, additional, Pivonello, Rosario, additional, and Isidori, Andrea M., additional

Published
2024
Full Text
View/download PDF

6. Biosignatures of defective sebaceous gland activity in sebum‐rich and sebum‐poor skin areas in adult atopic dermatitis

Author

Cavallo, Alessia, primary, Camera, Emanuela, additional, Bottillo, Grazia, additional, Maiellaro, Miriam, additional, Truglio, Mauro, additional, Marini, Federico, additional, Chavagnac‐Bonneville, Marlène, additional, Fauger, Aurélie, additional, Perrier, Eric, additional, Pigliacelli, Flavia, additional, Picardo, Mauro, additional, Cristaudo, Antonio, additional, and Mariano, Maria, additional

Published
2024
Full Text
View/download PDF

8. JAK/STAT Inhibition Normalizes Lipid Composition in 3D Human Epidermal Equivalents Challenged with Th2 Cytokines.

Author

Flori, Enrica, Cavallo, Alessia, Mosca, Sarah, Kovacs, Daniela, Cota, Carlo, Zaccarini, Marco, Di Nardo, Anna, Bottillo, Grazia, Maiellaro, Miriam, Camera, Emanuela, and Cardinali, Giorgia

Subjects
METABOLIC regulation, CYTOKINES, LIPID metabolism, LIPIDS, FILAGGRIN, CARBONIC anhydrase
Abstract

Derangement of the epidermal barrier lipids and dysregulated immune responses are key pathogenic features of atopic dermatitis (AD). The Th2-type cytokines interleukin IL-4 and IL-13 play a prominent role in AD by activating the Janus Kinase/Signal Transduction and Activator of Transcription (JAK/STAT) intracellular signaling axis. This study aimed to investigate the role of JAK/STAT in the lipid perturbations induced by Th2 signaling in 3D epidermal equivalents. Tofacitinib, a low-molecular-mass JAK inhibitor, was used to screen for JAK/STAT-mediated deregulation of lipid metabolism. Th2 cytokines decreased the expression of elongases 1, 3, and 4 and serine-palmitoyl-transferase and increased that of sphingolipid delta(4)-desaturase and carbonic anhydrase 2. Th2 cytokines inhibited the synthesis of palmitoleic acid and caused depletion of triglycerides, in association with altered phosphatidylcholine profiles and fatty acid (FA) metabolism. Overall, the ceramide profiles were minimally affected. Except for most sphingolipids and very-long-chain FAs, the effects of Th2 on lipid pathways were reversed by co-treatment with tofacitinib. An increase in the mRNA levels of CPT1A and ACAT1, reduced by tofacitinib, suggests that Th2 cytokines promote FA beta-oxidation. In conclusion, pharmacological inhibition of JAK/STAT activation prevents the lipid disruption caused by the halted homeostasis of FA metabolism. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

11. Evidence of defective fattyacidome and aminoacidome in sebaceous and non sebaceous skin surface in atopic dermatitis.

Author

Camera, Emanuela, primary, Cavallo, Alessia, additional, Mariano, Maria, additional, Bottillo, Grazia, additional, Maiellaro, Miriam, additional, Chavagnac-Bonneville, Marlène, additional, Fauger, Aurélie, additional, Perrier, Eric, additional, Pigliacelli, Flavia, additional, Truglio, Mauro, additional, Picardo, Mauro, additional, and Cristaudo, Antonio, additional

Published
2022
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results