218 results on '"Bornancin, Frédéric"'
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2. HDAC6/aggresome processing pathway importance for inflammasome formation is context-dependent
3. Integrating knowledge of protein sequence with protein function for the prediction and validation of new MALT1 substrates
4. Ligandability Assessment of IL-1β by Integrated Hit Identification Approaches
5. Inhibition of MALT1 paracaspase activity improves lesion recovery following spinal cord injury
6. Pharmacological inhibition of MALT1 protease activity suppresses endothelial activation via enhancing MCPIP1 expression
7. An allosteric MALT1 inhibitor is a molecular corrector rescuing function in an immunodeficient patient
8. CARD10 cleavage by MALT1 restricts lung carcinoma growth in vivo
9. A phospho-harmonic orchestra plays the NLRP3 score
10. Imaging Protein Kinase Cα Activation in Cells
11. Supplementary Data from MALT1 Is a Targetable Driver of Epithelial-to-Mesenchymal Transition in Claudin-Low, Triple-Negative Breast Cancer
12. Data from MALT1 Is a Targetable Driver of Epithelial-to-Mesenchymal Transition in Claudin-Low, Triple-Negative Breast Cancer
13. Ways and waves of MALT1 paracaspase activation
14. Structural Determinants of MALT1 Protease Activity
15. Ceramide kinase: The first decade
16. MALT1 Is a Targetable Driver of Epithelial-to-Mesenchymal Transition in Claudin-Low, Triple-Negative Breast Cancer
17. Pharmacological inhibition of IKKβ dampens NLRP3 inflammasome activation after priming in the human myeloid cell line THP-1
18. Subcellular localization of ceramide kinase and ceramide kinase-like protein requires interplay of their Pleckstrin Homology domain-containing N-terminal regions together with C-terminal domains
19. A secondary assay for ceramide kinase inhibitors based on cell growth inhibition by short-chain ceramides
20. Evaluation of protein kinase D auto-phosphorylation as biomarker for NLRP3 inflammasome activation
21. Regulation and Traffic of Ceramide 1-Phosphate Produced by Ceramide Kinase: COMPARATIVE ANALYSIS TO GLUCOSYLCERAMIDE AND SPHINGOMYELIN
22. A conserved cysteine motif essential for ceramide kinase function
23. Classification and Nomenclature of Metacaspases and Paracaspases: No More Confusion with Caspases
24. Sphingosine 1-phosphate phosphatase 2 is induced during inflammatory responses
25. Normal neutrophil functions in sphingosine kinase type 1 and 2 knockout mice
26. Effects of ceramide-1-phosphate on cultured cells: dependence on dodecane in the vehicle
27. Enhanced ceramide-induced apoptosis in ceramide kinase overexpressing cells
28. Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720
29. Discovery of Potent, Highly Selective, and In Vivo Efficacious, Allosteric MALT1 Inhibitors by Iterative Scaffold Morphing
30. Optimization of the In Vivo Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood
31. Stabilizing Inactive Conformations of MALT1 as an Effective Approach to Inhibit Its Protease Activity
32. Pharmacological Inhibition of MALT1 Protease Leads to a Progressive IPEX-Like Pathology
33. Requirement of Mucosa‐Associated Lymphoid Tissue Lymphoma Translocation Protein 1 Protease Activity for Fcγ Receptor–Induced Arthritis, but Not Fcγ Receptor–Mediated Platelet Elimination, in Mice
34. FTY720 Rescue Therapy in the Dark Agouti Rat Model of Experimental Autoimmune Encephalomyelitis: Expression of Central Nervous System Genes and Reversal of Blood-Brain-Barrier Damage
35. Characterization of a ceramide kinase-like protein
36. Basal and induced sphingosine kinase 1 activity in A549 carcinoma cells: function in cell survival and IL-1β and TNF-α induced production of inflammatory mediators
37. The role of sphingosine and ceramide kinases in inflammatory responses
38. Classification and nomenclature of metacaspases and paracaspases: No more confusion with caspases
39. Ceramide kinase targeting and activity determined by its N-terminal pleckstrin homology domain
40. MALT1 activation by TRAF6 needs neither BCL10 nor CARD11
41. A CARD10-Dependent Tonic Signalosome Activates MALT1 Paracaspase and Regulates IL-17/TNF-α–Driven Keratinocyte Inflammation
42. N-aryl-piperidine-4-carboxamides as a novel class of potent inhibitors of MALT1 proteolytic activity
43. Phosphorylation of the Immunomodulatory Drug FTY720 by Sphingosine Kinases
44. Malt1 Protease Deficiency in Mice Disrupts Immune Homeostasis at Environmental Barriers and Drives Systemic T Cell–Mediated Autoimmunity
45. Editorial: CARMA Proteins: Playing a Hand of Four CARDs
46. Ovalbumin-induced plasma interleukin-4 levels are reduced in ceramide kinase-deficient DO11.10 RAG1-/- mice
47. Ligand modulation of [ 35S]GTPγS binding at human α 2A, α 2B and α 2C adrenoceptors
48. Selective MALT1 paracaspase inhibition does not block TNF-α production downstream of TLR4 in myeloid cells
49. The T-cell fingerprint of MALT1 paracaspase revealed by selective inhibition
50. Ways and waves of MALT1 paracaspase activation
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