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Your search keyword '"Besnard, S."' showing total 266 results
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266 results on '"Besnard, S."'

1. FDG-PET/CT findings in systemic mastocytosis: a French multicentre study

Author

Djelbani-Ahmed, S., Chandesris, M. O., Mekinian, A., Canioni, D., Brouzes, C., Hanssens, K., Pop, G., Durieu, I., Durupt, S., Grosbois, B., Besnard, S., Tournilhac, O., Beyne-Rauzy, O., Agapé, P., Delmer, A., Ranta, D., Jeandel, P. Y., Georgin-Lavialle, S., Frenzel, L., Damaj, G., Eder, V., Lortholary, O., Hermine, O., Fain, O., and Soussan, M.

Published
2015
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3. Environment-sensitivity functions for gross primary productivity in light use efficiency models

Author

Bao, S, Wutzler, T, Koirala, S, Cuntz, M, Ibrom, A, Besnard, S, Walther, S, Šigut, L, Moreno, A, Weber, U, Wohlfahrt, G, Cleverly, J, Migliavacca, M, Woodgate, W, Merbold, L, Veenendaal, E, Carvalhais, N, Bao, S, Wutzler, T, Koirala, S, Cuntz, M, Ibrom, A, Besnard, S, Walther, S, Šigut, L, Moreno, A, Weber, U, Wohlfahrt, G, Cleverly, J, Migliavacca, M, Woodgate, W, Merbold, L, Veenendaal, E, and Carvalhais, N

Abstract

The sensitivity of photosynthesis to environmental changes is essential for understanding carbon cycle responses to global climate change and for the development of modeling approaches that explains its spatial and temporal variability. We collected a large variety of published sensitivity functions of gross primary productivity (GPP) to different forcing variables to assess the response of GPP to environmental factors. These include the responses of GPP to temperature; vapor pressure deficit, some of which include the response to atmospheric CO2 concentrations; soil water availability (W); light intensity; and cloudiness. These functions were combined in a full factorial light use efficiency (LUE) model structure, leading to a collection of 5600 distinct LUE models. Each model was optimized against daily GPP and evapotranspiration fluxes from 196 FLUXNET sites and ranked across sites based on a bootstrap approach. The GPP sensitivity to each environmental factor, including CO2 fertilization, was shown to be significant, and that none of the previously published model structures performed as well as the best model selected. From daily and weekly to monthly scales, the best model's median Nash-Sutcliffe model efficiency across sites was 0.73, 0.79 and 0.82, respectively, but poorer at annual scales (0.23), emphasizing the common limitation of current models in describing the interannual variability of GPP. Although the best global model did not match the local best model at each site, the selection was robust across ecosystem types. The contribution of light saturation and cloudiness to GPP was observed across all biomes (from 23% to 43%). Temperature and W dominates GPP and LUE but responses of GPP to temperature and W are lagged in cold and arid ecosystems, respectively. The findings of this study provide a foundation towards more robust LUE-based estimates of global GPP and may provide a benchmark for other empirical GPP products.

Published
2022

11. Les recommandations nationales françaises de prise en charge du cancer du sein infiltrant: Onze questions cliniques d’actualité sur le bilan initial, la radiothérapie et les traitements systémiques

Author

Giard, S., Cutuli, B., Antoine, M., Barreau, B., Besnard, S., Bonneterre, J., Campone, M., Ceugnard, L., Classe, J. M., Cohen, M., Dohoullou, N., Fourquet, A., Guinebretière, J. M., Hennequin, C., Leblanc-Onfroy, M., Levy, L., Mazeau-Woynar, V., Mouret Reynier, M. A., Rousseau, C., and Verdoni, L.

Published
2013
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23. Morphological and functional correlates of vestibular synaptic deafferentation and repair in a mouse model of acute onset vertigo

Author

Cassel, R., primary, Bordiga, P., additional, Carcaud, J., additional, Simon, F., additional, Beraneck, M., additional, Le Gall, A., additional, Benoit, A., additional, Bouet, V., additional, Philoxene, B., additional, Besnard, S., additional, Watabe, I., additional, Pericat, D., additional, Hautefort, C., additional, Assie, A., additional, Tonetto, A., additional, Dyhrfjeld-Johnsen, J., additional, Llorens, J., additional, Tighilet, B., additional, and Chabbert, C., additional

Published
2019
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31. Intérêt du dosage de l’immunoglobuline monoclonale complète lors du diagnostic ou du suivi des patients présentant un myélome à immunoglobuline complète : l’électrophorèse des protéines sériques et l’immonofixation ne seraient-elles pas suffisantes ? [Heavy/light chain specific immunoglobulin ratios provides no additional information than serum proteins electrophoresis and immunofixation for the diagnosis and the follow-up of intact immunoglobulin multiple myeloma patients]

Author

Beaumont-Epinette, M. -P., Moreau, Caroline, Besnard, S., Latute, F., Collet, N., Sebillot, M., Grosbois, B., Bendavid, C., Guenet, L., Decaux, O, CHU Pontchaillou [Rennes], Foie, métabolismes et cancer, Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), Institut de Génétique et Développement de Rennes (IGDR), Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Centre National de la Recherche Scientifique (CNRS)-Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES), Université de Rennes (UR)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique ), and Université de Rennes (UR)-Centre National de la Recherche Scientifique (CNRS)-Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )

Subjects
Immunofixation, Surveillance, Monitoring, Serum protein electrophoresis, [SDV]Life Sciences [q-bio], Serum immunofixationés, Rechute, Myélome multiple, Diagnosis, Diagnostic, Relapse, Électrophorèse des protéines sériques, Multiple Myeloma, ComputingMilieux_MISCELLANEOUS
Abstract

International audience

Published
2015

38. Heavy/light chain specific immunoglobulin ratios provides no additional information than serum proteins electrophoresis and immunofixation for the diagnosis and the follow-up of intact immunoglobulin multiple myeloma patients

Author

Beaumont-Epinette, M.-P., primary, Moreau, C., additional, Besnard, S., additional, Latute, F., additional, Collet, N., additional, Sebillot, M., additional, Grosbois, B., additional, Bendavid, C., additional, Guenet, L., additional, and Decaux, O., additional

Published
2015
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40. Sympathetic B antagonist prevents bone mineral density decrease induced by labyrinthectomy

Author

Pierre Denise, Besnard, S., Vignaux, G., Sabatier, J. P., Edy, E., Hitier, M., and Levasseur, R.

Subjects
Sympathetic Nervous System, Adrenergic beta-Antagonists, Propranolol, Rats, Disease Models, Animal, Absorptiometry, Photon, Bone Density, Animals, Female, Femur, Vestibule, Labyrinth, Bone Resorption, Rats, Wistar, Follow-Up Studies
Abstract

We previously showed that bilateral vestibular lesion in rats induces a bone loss in weight bearing bones. To determine whether this effect is mediated by the sympathetic nervous system (SNS), bone mineral density (BMD) was measured in 4 groups of 10 female Wistar rats: bilateral labyrinthectomy (Bilab), Bilab with propranolol treatment, sham operated with or withoutpropranolol. In untreated rats, 30 days after lesion Bilab animals showed a reduced BMD in distal femoral metaphysis comparatively to intact rats (p0.001). In treated rats, there was no difference in BMD 30 days after lesion. This protective effect of propranolol against bone loss suggests that the vestibular system influence on bone remodeling is mediated by SNS. If this hypothesis is correct, this could have important consequences in devising countermeasures to spaceflight induced bone loss.

Published
2010

41. Integrative function of single neurons in the human subthalamic nucleus during checking behavior

Author

Burbaud, P., Welter, M. -L, Goillandeau, M., Clair, A. -L, Sauleau, P., Simonetta-Moreau, M., Chabardes, S., Besnard, S., Magnie-Mauro, H., Coste, J., Luc Mallet, Institut des Maladies Neurodégénératives [Bordeaux] (IMN), Université de Bordeaux (UB)-Centre National de la Recherche Scientifique (CNRS), Institut du Cerveau et de la Moëlle Epinière = Brain and Spine Institute (ICM), Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), Comportement et noyaux gris centraux = Behavior and Basal Ganglia [Rennes], Université de Rennes (UR)-Université européenne de Bretagne - European University of Brittany (UEB)-CHU Pontchaillou [Rennes]-Institut des Neurosciences Cliniques de Rennes = Institute of Clinical Neurosciences of Rennes (INCR), Imagerie cérébrale et handicaps neurologiques (ICHN), Institut des sciences du cerveau de Toulouse. (ISCT), Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Université de Toulouse (UT)-Université Toulouse III - Paul Sabatier (UT3), Université de Toulouse (UT)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse - Jean Jaurès (UT2J), Université de Toulouse (UT)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Grenoble Institut des Neurosciences (GIN), Université Joseph Fourier - Grenoble 1 (UJF)-Institut National de la Santé et de la Recherche Médicale (INSERM), Neurophysiologie Clinique, Centre hospitalier universitaire de Poitiers (CHU Poitiers), Laboratoire de psychologie cognitive et sociale (LPCS), Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA), Institut Pascal (IP), SIGMA Clermont (SIGMA Clermont)-Université Clermont Auvergne [2017-2020] (UCA [2017-2020])-Centre National de la Recherche Scientifique (CNRS), Service de Neurochirurgie [CHU Clermont-Ferrand], CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Clermont-Ferrand, Institut du Cerveau = Paris Brain Institute (ICM), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS), International Parkinson and Movement Disorder Society, Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Université européenne de Bretagne - European University of Brittany (UEB)-CHU Pontchaillou [Rennes]-Institut des Neurosciences Cliniques de Rennes (INCR), Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Toulouse - Jean Jaurès (UT2J)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Nice Sophia Antipolis (... - 2019) (UNS), Service de Neurochirurgie [Clermont-Ferrand], CHU Clermont-Ferrand-CHU Gabriel Montpied [Clermont-Ferrand], CHU Clermont-Ferrand, Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

Subjects
nervous system, [SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology, [SDV.MHEP.PSM]Life Sciences [q-bio]/Human health and pathology/Psychiatrics and mental health, clinical electrophysiology, [SDV.MHEP.CHI]Life Sciences [q-bio]/Human health and pathology/Surgery
Abstract

International audience; Objective: To study the role of the subthalamic nucleus (STN) in the processing of cognitive information during checking behaviour in patients with obsessive compulsive behaviour (OCD). Background: Human behavior depends on complex interactions between cognition and emotion. How does the brain combine these two dimensions to make a decision and elaborate a goal-directed action remains unclear. One hypothesis is that such an integrative process might occur owing to the convergence of information through the basal ganglia. Recently, the associative and limbic STN have been proposed as potential targets for deep brain stimulation in patients with medically-resistant form of OCD1. We took the opportunity of the last study to investigate the role of STN neurons in the processing of cognitive information.Methods: We used an instrumental task (CT), adapted from a matching to sample-task, that specifically offered the opportunity to verify once one subject has made a choice2. Single unit neuronal activity was recorded in the STN whereas patients with obsessive compulsive disorders (OCD) performed the CT. Results: Among 125 single neurons recorded during task performance, 45 (36%) were task-related. Modifications of activity were observed in relation with: visual information during the study phase (28%), the choice phase (22%), or the checking phase (20%), movement execution during the choice phase (37%), or the checking phase (35%) and during the evaluation phase at the end of the task (56%). We found that STN neurons frequently responded in a polymodal manner to cognitive, premotor and emotional events. Moreover, discharge frequency was influenced by checking behavior.Conclusions: These results suggest that STN neurons process multiple sources of information in accordance with the model of information convergence within the basal ganglia. They also demonstrate that the STN play a part in the physiology of doubt, a critical feature of OCD pathophysiology.

Published
2009

42. Effet des TCSL sur la circulation de l'eau

Author

Michot, Didier, Hallaire, V., Besnard, S., Sol Agro et hydrosystème Spatialisation (SAS), Institut National de la Recherche Agronomique (INRA)-AGROCAMPUS OUEST, AGROCAMPUS OUEST, and Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut National de la Recherche Agronomique (INRA)

Subjects
[SDV.SA.AGRO]Life Sciences [q-bio]/Agricultural sciences/Agronomy
Abstract

Effet des TCSL sur la circulation de l'eau

Published
2009

46. Computational Models of Argument : Proceedings of COMMA 2008

Author

Ph. Besnard, S. Doutre, A. Hunter and Ph. Besnard, S. Doutre, A. Hunter

Subjects
Reasoning--Computer simulation--Congresses, Artificial intelligence--Computer simulation--Congresses
Abstract

Focuses on the aim to develop software tools to assist users in constructing and evaluating arguments and counterarguments and/or to develop automated systems for constructing and evaluating arguments and counterarguments. This book includes articles, which provide a snapshot of research questions in the area of computational models of argument.

Published
2008

49. Maladie d’Erdheim-Chester : étude monocentrique de 96 patients

Author

Haroche, J., primary, Cohen-Aubart, F., additional, Arnaud, L., additional, Hervier, B., additional, Saadoun, D., additional, Costedoat-Chalumeau, N., additional, Besnard, S., additional, Ly, K.-H., additional, Pavic, M., additional, Baudet, A., additional, Raffray, L., additional, and Amoura, Z., additional

Published
2013
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